Marta Klak, Michał Wszoła, Andrzej Berman, Anna Filip, Anna Kosowska, Joanna Olkowska-Truchanowicz, Michał Rachalewski, Grzegorz Tymicki, Tomasz Bryniarski, Marta Kołodziejska, Tomasz Dobrzański, Dominika Ujazdowska, Jarosław Wejman, Izabela Uhrynowska-Tyszkiewicz, Artur Kamiński
Recently, tissue engineering, including 3D bioprinting of the pancreas, has acquired clinical significance and has become an outstanding potential method of customized treatment for type 1 diabetes mellitus. The study aimed to evaluate the function of 3D-bioprinted pancreatic petals with pancreatic islets in the murine model. A total of 60 NOD-SCID (Nonobese diabetic/severe combined immunodeficiency) mice were used in the study and divided into three groups: control group; IsletTx (porcine islets transplanted under the renal capsule); and 3D bioprint (3D-bioprinted pancreatic petals with islets transplanted under the skin, on dorsal muscles)...
July 14, 2023: Journal of Functional Biomaterials