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https://www.readbyqxmd.com/read/28439813/simultaneous-heavy-metal-removal-and-anthracene-biodegradation-by-the-oleaginous-bacteria-rhodococcus-opacus
#1
Lalit Goswami, N Arul Manikandan, Kannan Pakshirajan, G Pugazhenthi
This study investigated simultaneous heavy metals removal and anthracene biodegradation by Rhodococcus opacus at different initial anthracene concentrations in the range 50-200 mg L(-1). The heavy metals tested were Fe(III), Cu(II), Zn(II), Cd(II), Ni(II), and Pb(II) at 10 mg L(-1) initial concentration: The organism was found to be well capable of removing the heavy metals along with high anthracene biodegradation efficiency. However, anthracene biodegradation rate by the organism was reduced due to these heavy metals...
May 2017: 3 Biotech
https://www.readbyqxmd.com/read/28433612/use-of-enteroscopy-for-the-detection-of-malignant-and-pre-malignant-lesions-of-the-small-bowel-in-complicated-celiac-disease-a-meta-analysis
#2
REVIEW
Luca Elli, Giovanni Casazza, Martina Locatelli, Federica Branchi, Francesca Ferretti, Dario Conte, Mirella Fraquelli
BACKGROUND AND AIMS: Enteroscopy (wireless, wired) is the reference standard for small-bowel (SB) diseases and it has been applied to detect SB malignancies in complicated celiac disease (CD) with heterogeneous results. The aim of this meta-analysis is to obtain a diagnostic yield (DY) by pooling the data of studies that investigated the use of enteroscopy to detect SB adverse events in CD. METHODS: We performed an online search for studies estimating the DY of wireless and wired enteroscopy in predicting the presence of SB pre-malignant and/or malignant lesions...
April 19, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28431391/serum-levels-of-lead-mercury-and-cadmium-in-relation-to-coronary-artery-disease-in-the-elderly-a-cross-sectional-study
#3
Sedigheh Asgary, Ahmad Movahedian, Mahtab Keshvari, Mahsa Taleghani, Amirhossein Sahebkar, Nizal Sarrafzadegan
BACKGROUND: There is a continuing attempt to identify novel factors that can predict the risk of cardiovascular disease beyond the established coronary risk factors. It has been suggested that serum levels of lead, mercury and cadmium are associated with the risk of coronary artery disease (CAD). In the present study, we aimed to evaluate serum concentrations of lead (s-Pb), mercury (s-Hg) and cadmium (s-Cd) in patients with CAD in comparison with those of healthy individuals. The correlation between serum levels of these heavy metals and lipid profile parameters was also investigated...
March 29, 2017: Chemosphere
https://www.readbyqxmd.com/read/28420202/cereal-consumption-among-subjects-with-celiac-disease-a-snapshot-for-nutritional-considerations
#4
Francesco Valitutti, Donatella Iorfida, Caterina Anania, Chiara Maria Trovato, Monica Montuori, Salvatore Cucchiara, Carlo Catassi
BACKGROUND: To our knowledge no study has focused on the pattern of cereal-based products (CBP) consumption among people with celiac disease (CD). Our study aimed at evaluating the dietary intake of CBP among patients with CD and comparing it with a control population. METHODS: Eighty-two volunteers with CD and 77 non-CD volunteers enrolled throughout Italy were asked to register their consumption of CBP on specific diaries for three days. RESULTS: CD patients' median three-day intake of biscuits and crackers was higher compared to controls (65...
April 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28412702/case-control-study-on-dactylitis-enthesitis-and-anterior-uveitis-in-spondyloarthritis-associated-with-inflammatory-bowel-diseases-role-of-coexistent-psoriasis
#5
Fabrizio Cantini, Laura Niccoli, Carlotta Nannini, Emanuele Cassarà, Olga Kaloudi, Fernando Rizzello, Paolo Gionchetti
OBJECTIVE: To evaluate the frequency of dactylitis, enthesitis, and anterior uveitis (AU) in spondyloarthritis (SpA) associated with inflammatory bowel disease (IBD-SpA) compared with other SpA, and to assess the role of associated psoriasis in the occurrence of dactylitis and enthesitis. METHODS: In a 12-month case-control study, the frequency of dactylitis and enthesitis in 29 patients with ulcerative colitis (UC) and 59 with Crohn disease (CD) who satisfied the Spondyloarthritis international Society criteria for axial or peripheral SpA was compared with 176 controls, including 97 (55...
April 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28398922/characterization-of-cardiac-dysfunction-by-echocardiography-in-early-severe-acute-pancreatitis
#6
Ragesh Babu Thandassery, Nikhil Choudhary, Ajay Bahl, Rakesh Kochhar
OBJECTIVE: Persistent organ failure is a feature of severe acute pancreatitis (SAP) and the leading cause of death. Although usually defined by hypotension, cardiovascular dysfunction (CD) in early SAP has not been well characterized. We aim to characterize CD in patients with SAP and hypotension and determine its impact on clinical outcome. METHODS: Patients with SAP and hypotension were studied to define the frequency, nature, and prognostic significance of CD characterized by echocardiography and classified as systolic, diastolic, or combined dysfunction...
May 2017: Pancreas
https://www.readbyqxmd.com/read/28395264/polycyclic-aromatic-hydrocarbons-and-their-derivatives-nitro-pahs-oxygenated-pahs-and-azaarenes-in-pm2-5-from-southern-european-cities
#7
Célia A Alves, Ana M Vicente, Danilo Custódio, Mário Cerqueira, Teresa Nunes, Casimiro Pio, Franco Lucarelli, Giulia Calzolai, Silvia Nava, Evangelia Diapouli, Konstantinos Eleftheriadis, Xavier Querol, Benjamin A Musa Bandowe
Atmospheric particulate matter (PM2.5) samples were collected over two one month periods during winter and summer in three Southern European cities (Oporto - traffic site, Florence - urban background, Athens - suburban). Concentrations of 27 polycyclic aromatic hydrocarbons (PAHs), 15 nitro-PAHs (NPAHs), 15 oxygenated-PAHs (OPAHs) and 4 azaarenes (AZAs) were determined. On average, the winter-summer concentrations of ΣPAHs were 16.3-5.60, 7.75-3.02 and 3.44-0.658ngm(-3) in Oporto, Florence and Athens, respectively...
April 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28365517/host-guest-kinetic-interactions-between-hp-%C3%AE-cyclodextrin-and-drugs-for-prediction-of-bitter-taste-masking
#8
Zhen Guo, Fei Wu, Vikramjeet Singh, Tao Guo, Xiaohong Ren, Xianzhen Yin, Qun Shao, Peter York, Laurence H Patterson, Jiwen Zhang
Cyclodextrins (CD) are widely used bitter taste masking agents, for which the binding equilibrium constant (K) for the drug-CD complex is a conventional parameter for quantitating the taste masking effects. However, some exceptions have been reported to the expected relationship between K and bitterness reduction and the relationship between kinetic parameters of a drug-CD interaction, including association rate constant (Ka) and disassociation rate constant (Kd), and taste masking remains unexplored. In this study, based upon a database of kinetic parameters of drugs-HP-β-CD generated by Surface Plasmon Resonance Imaging for 485 drugs, the host-guest kinetic interactions between drugs and HP-β-CD for prediction of taste masking effects have been investigated...
June 5, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28359357/hmgb1-as-a-new-biomarker-of-celiac-disease-in-children-a%C3%A2-multicenter-study
#9
Sara Manti, Caterina Cuppari, Lucia Tardino, Giuseppe Parisi, Massimo Spina, Carmelo Salpietro, Salvatore Leonardi
OBJECTIVE: Despite the availability of specific sierology and point-of-care tests, the phenotypic heterogeneity and the symptoms fluctuation as well as the "open-window" existing among the late and silent forms cause often a delayed celiac disease (CD) diagnosis. Recently, it has been reported that high mobility group box 1 (HMGB1) mediates inflammation and gastrointestinal barrier failure. The aim of this study was to detect serum HMGB1 levels at CD diagnosis and to evaluate the relationship between serum HMGB1 levels and clinical and histologic phenotypes...
May 2017: Nutrition
https://www.readbyqxmd.com/read/28356986/hypoxia-regulates-cd44-expression-via-hypoxia-inducible-factor-1%C3%AE-in-human-gastric-cancer-cells
#10
Gai Liang, Shuang Li, Wei Du, Qinghua Ke, Jun Cai, Jiyuan Yang
Hypoxia induces proliferation and invasion in cancer cells via hypoxia-inducible factor (HIF)-1α. The cell adhesion molecule cluster of differentiation (CD) 44 has been associated with increased cell invasion and metastasis. Whether hypoxia regulates the expression of CD44 in gastric cancer cells remains to be established. In the current study, the effects of hypoxia on HIF-1α and CD44 expression levels in human gastric cell lines SGC-7901 and BGC-823 were evaluated. The cells were cultured in 1% O2 for 1 week and then treated with 20 nM rapamycin for 72 h...
February 2017: Oncology Letters
https://www.readbyqxmd.com/read/28342080/heavy-metals-bioconcentration-from-soil-to-vegetables-and-appraisal-of-health-risk-in-koka-and-wonji-farms-ethiopia
#11
Temesgen Eliku, Seyoum Leta
Heavy metal accumulation in agricultural crops has grown a major concern globally as a result of a significant health impact on human. The quantification of heavy metals (Cd, Pb, Cr, Zn, Cu, and Ni) in the soil and vegetables at two sites (Koka and Wonji Gefersa) was done using flame atomic absorption spectrophotometer. The mean concentrations of heavy metals in vegetable fields' soil samples obtained from Koka were higher for Pb, Cr, Zn, Cu, and Ni. The overall results of soil samples ranged 0.52-0.93, 13...
March 24, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28340712/a-double-mediator-based-whole-cell-electrochemical-biosensor-for-acute-biotoxicity-assessment-of-wastewater
#12
Guanyue Gao, Deyu Fang, Yuan Yu, Liangzhuan Wu, Yu Wang, Jinfang Zhi
This work investigates the feasibility and sensitivity of a double-mediator based whole cell electrochemical biosensor to detect the acute biotoxicity of wastewater. The lipophilic mediator menadione was used to mediate the intracellular metabolic activities whereas hydrophilic potassium ferricyanide was employed as extracellular electron acceptor to transport the electron from the menadiol to anode. A chitosan hydrogel polymer film with boron-doped nanocrystalline diamond (BND) particles was electrodeposited onto a glassy carbon (GC) electrode to immobilize Saccharomyces cerevisiae cells and the mediators...
May 15, 2017: Talanta
https://www.readbyqxmd.com/read/28335292/a-tunable-photoluminescent-composite-of-cellulose-nanofibrils-and-cds-quantum-dots
#13
Qinwen Wang, Aimin Tang, Yuan Liu, Zhiqiang Fang, Shiyu Fu
The preparation of fluorescent nanocomposite materials with tunable emission wavelengths by combining cellulose nanofibrils (CNFs) with inorganic nanoparticles is important for promoting CNFs applications. A CNF/CdS nanocomposite was prepared via in situ compositing at room temperature on oxidized CNFs with CdS quantum dots. By controlling the -COOH/Cd(2+) ratio on the CNF, the feeding time of Na₂S and the ultrasonic maturing time, the size of the CdS quantum dots on the CNF surface could be adjusted so that to obtain the CNF/CdS nanocomposite material with different fluorescent colors...
September 7, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28319859/use-of-clay-to-remediate-cadmium-contaminated-soil-under-different-water-management-regimes
#14
Jianrui Li, Yingming Xu
We examined in situ remediation of sepiolite on cadmium-polluted soils with diverse water regimes, and several variables including brown rice Cd, exchangeable Cd, pH, and available Fe/P. pH, available Fe/P in soils increased gradually during continuous flooding, which contributed to Cd absorption on colloids. In control group (untreated soils), compared to conventional irrigation, brown rice Cd in continuous flooding reduced by 37.9%, and that in wetting irrigation increased by 31.0% (p<0.05). In contrast to corresponding controls, brown rice Cd in sepiolite treated soils reduced by 44...
March 17, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28315037/incidence-of-and-risk-factors-for-free-bowel-perforation-in-patients-with-crohn-s-disease
#15
Jong Wook Kim, Ho-Su Lee, Byong Duk Ye, Suk-Kyun Yang, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kyung-Jo Kim, Jeong-Sik Byeon, Seung-Jae Myung, Yong Sik Yoon, Chang Sik Yu, Jin-Ho Kim
BACKGROUND: Incidence of and risk factors for intestinal free perforation (FP) in patients with Crohn's disease (CD) are not established. AIM: To establish rate of and risk factors for FP in a large cohort of CD patients. METHODS: Medical records of CD patients who visited Asan Medical Center from June 1989 to December 2012 were reviewed. After matching the FP patients to controls (1:4) by gender, year, and age at CD diagnosis, and disease location, their clinical characteristics were compared using conditional logistic regression analysis...
March 17, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28302320/platelet-reactivity-and-mean-platelet-volume-as-risk-markers-of-thrombogenesis-in-atrial-fibrillation
#16
Marcin Makowski, Ireneusz Smorag, Joanna Makowska, Andrzej Bissinger, Tomasz Grycewicz, Jarek Paśnik, Michal Kidawa, Andrzej Lubiński, Marzenna Zielińska, Zbigniew Baj
Atrial fibrillation (AF) is associated with increased risk of thromboembolic complications. One of the markers of the increased risk of hypercoagulable state is platelet hyperreactivity. The aim of the study was to assess impact of arrhythmia on platelet reactivity. METHODS: The study included 36 (mean age 48,3; range 21-60) male patients with lone atrial fibrillation, with exclusion of concomitant diseases known to trigger hypercoagulable state. The AF patients underwent cardioversion to restore sinus rhythm and were subsequently under observation for 1month...
May 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28292671/heavy-metal-bioaccumulation-in-two-passerines-with-differing-migration-strategies
#17
Zoë Cooper, Robert Bringolf, Robert Cooper, Kathy Loftis, Albert L Bryan, James A Martin
Various anthropogenic activities have resulted in concentration of heavy metals and contamination of surrounding environments. Historically, heavy metal contamination at the Savannah River Site (SRS) in South Carolina has resulted from accidental releases of stored waste generated from nuclear weapon production in the early 1950s. Songbirds inhabiting and using resources from these areas have the potential to bioaccumulate metals but there is limited information on metal concentration levels in areas suspected of contamination as well as uncontaminated sites...
March 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28281165/effectiveness-and-safety-of-ct-p13-biosimilar-infliximab-in-patients-with-inflammatory-bowel-disease-in-real-life-at-6%C3%A2-months
#18
F Argüelles-Arias, M F Guerra Veloz, R Perea Amarillo, A Vilches-Arenas, L Castro Laria, B Maldonado Pérez, D Chaaro, A Benítez Roldán, V Merino, G Ramírez, A Caunedo Álvarez, M Romero Gómez
BACKGROUND: CT-P13 is a biosimilar of Remicade(®), an agent approved in some countries for use in inflammatory bowel disease (IBD). Controlled clinical trials have demonstrated the efficacy and safety of CT-P13 in rheumatic diseases, but not in IBD. AIMS: To assess the effectiveness and safety of CT-P13 in IBD patients in real clinical practice. METHODS: This is a prospective observational study in patients with moderate to severe Crohn's disease or ulcerative colitis treated with CT-P13...
May 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28271723/interaction-of-iron-nanoparticles-with-nervous-system-an-invitro-study
#19
Gelare Hajsalimi, Saba Taheri, Farshad Shahi, Leila Pishkar, Farnoosh Attar, Hosein Ahmadi, Mojtaba Falahati
Nanoparticles (NPs) are one of interesting and widely studying issues mainly because of their particular physico-chemical features and broad applications in the field of biomedical sciences, such as diagnosis and drug delivery. In this study, the interaction of iron nanoparticles (Fe-NPs) with Tau protein and PC12 cell, as potential nervous system models, was investigated with a range of techniques including dynamic light scattering (DLS), intrinsic fluorescence spectroscopy, circular dichroism (CD), [(3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazolium-bromid] (MTT) assay, and acridine orange/ethidium bromide (AO/EB) dual staining method...
March 8, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28265826/intestinal-inflammation-does-not-predict-nonalcoholic-fatty-liver-disease-severity-in-inflammatory-bowel-disease-patients
#20
Rotonya M Carr, Arpan Patel, Hillary Bownik, Amanke Oranu, Caroline Kerner, Amy Praestgaard, Kimberly A Forde, K Rajender Reddy, Gary R Lichtenstein
BACKGROUND AND AIM: Nonalcoholic fatty liver disease (NAFLD) is a common cause of hepatic steatosis in patients with inflammatory bowel disease (IBD). Both metabolic syndrome (MetS) and intestinal inflammation are implicated in NAFLD pathogenesis. METHODS: We performed a retrospective cohort study of patients with IBD and NAFLD seen in our health system from January 1997 to December 2011 to examine associations between IBD severity and phenotype; MetS; and NAFLD fibrosis as estimated by the NAFLD Fibrosis Score (NFS)...
May 2017: Digestive Diseases and Sciences
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