keyword
MENU ▼
Read by QxMD icon Read
search

stem cells, acupuncture,

keyword
https://www.readbyqxmd.com/read/29111577/applications-of-acupuncture-therapy-in-modulating-plasticity-of-central-nervous-system
#1
REVIEW
Ling-Yong Xiao, Xue-Rui Wang, Ye Yang, Jing-Wen Yang, Yan Cao, Si-Ming Ma, Tian-Ran Li, Cun-Zhi Liu
OBJECTIVE: Acupuncture is widely applied for treatment of various neurological disorders. This manuscript will review the preclinical evidence of acupuncture in mediating neural plasticity, the mechanisms involved. MATERIALS AND METHODS: We searched acupuncture, plasticity, and other potential related words at the following sites: PubMed, EMBASE, Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), and VIP information data base. The following keywords were used: acupuncture, electroacupuncture, plasticity, neural plasticity, neuroplasticity, neurogenesis, neuroblast, stem cell, progenitor cell, BrdU, synapse, synapse structure, synaptogenesis, axon, axon regeneration, synaptic plasticity, LTP, LTD, neurotrophin, neurotrophic factor, BDNF, GDNF, VEGF, bFGF, EGF, NT-3, NT-4, NT-5, p75NTR, neurotransmitter, acetylcholine, norepinephrine, noradrenaline, dopamine, monamine...
November 7, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28920142/acupuncture-for-reduction-of-symptom-burden-in-multiple-myeloma-patients-undergoing-autologous-hematopoietic-stem-cell-transplantation-a-randomized-sham-controlled-trial
#2
Gary Deng, Sergio Giralt, David J Chung, Heather Landau, Jonathan Siman, Benjamin Search, Marci Coleton, Emily Vertosick, Nathan Shapiro, Christine Chien, Xin S Wang, Barrie Cassileth, Jun J Mao
PURPOSE: Hematopoietic stem cell transplantation (HCT) is potentially curative for a number of hematologic malignancies, but is associated with high symptom burden. We conducted a randomized sham-controlled trial (RCT) to evaluate efficacy and safety of acupuncture as an integrative treatment for managing common symptoms during HCT. METHODS: Adult patients with multiple myeloma undergoing high-dose melphalan followed by autologous HCT (AHCT) were randomized to receive either true or sham acupuncture once daily for 5 days starting the day after chemotherapy...
September 17, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28807156/metabolic-factors-and-adult-neurogenesis-impacts-of-chinese-herbal-medicine-on-brain-repair-in-neurological-diseases
#3
Chong Gao, Jiangang Shen
Adult neurogenesis plays the important roles in animal cognitive and emotional behaviors. Abnormal proliferation and differentiation of neural stem cells (NSCs) usually associate with the neural dysfunctions induced by different brain disorders. Therefore, targeting neurogenic factors could be a promoting strategy for neural regeneration and brain repair. Importantly, epidemiological studies suggest metabolism disorders like diabetes and obesity significantly increase the risk of neurological and psychiatric diseases...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/28627669/recovery-of-spinal-cord-injury-following-electroacupuncture-in-rats-through-enhancement-of-wnt-%C3%AE-catenin-signaling
#4
Junfeng Zhang, Shisheng Li, Yaochi Wu
Electroacupuncture (EA) has been demonstrated to promote the functional recovery of neurons following spinal cord injury (SCI); however, the mechanisms underlying its effects have yet to be elucidated. The Wnt/β-catenin signaling pathway has been implicated in the regulation of the balance between growth, proliferation and differentiation of neural precursor cells. The present study aimed to investigate the effects of EA therapy on Wnt/β‑catenin‑regulated gene expression and neuronal recovery in rats with SCI...
August 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28507480/electro-acupuncture-promotes-the-proliferation-of-neural-stem-cells-and-the-survival-of-neurons-by-downregulating-mir-449a-in-rat-with-spinal-cord-injury
#5
Yi Zhu, Yaochi Wu, Rong Zhang
The aim of this study is to investigate the mechanism of electro-acupuncture (EA) on the recovery of injured spinal cord. Rats were randomly divided into normal control, sham-operated, SCI, SCI+EA group and T10 segment spinal cord injury (SCI) rat model was established by the modified Allen's method. After 7 days, the mRNA and protein expression of Nestin, neuron specific nuclear protein (NeuN) and calcitonin gene related peptide (CGRP) were detected by real time RT-PCR, Western blot and immunohistochemistry respectively...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28461125/modulation-of-neurogenesis-via-neurotrophic-factors-in-acupuncture-treatments-for-neurological-diseases
#6
REVIEW
Hwa Kyoung Shin, Sae-Won Lee, Byung Tae Choi
Acupuncture is one of the main healing arts in Oriental medicine. It has long been used in East Asian countries, including Korea and China, and is thought to be an effective alternative treatment for various neurological diseases. The therapeutic effects of acupuncture come from inserting a needle at specific acupoints on the body surface, with subsequent delivery of stimulation via manual rotation or electric pulses (electroacupuncture, EA). In various neurological disease models, peripheral nerve stimulation using acupuncture or EA may have protective effects on neural tissues by increasing expression of neurotrophic factors (NTFs), such as brain-derived neurotrophic factor and glial-derived neurotrophic factor, in the central nervous system, especially the brain...
October 1, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28299842/electroacupuncture-promotes-central-nervous-system-dependent-release-of-mesenchymal-stem-cells
#7
Tatiana E Salazar, Matthew R Richardson, Eleni Beli, Matthew S Ripsch, John George, Youngsook Kim, Yaqian Duan, Leni Moldovan, Yuanqing Yan, Ashay Bhatwadekar, Vaishnavi Jadhav, Jared A Smith, Susan McGorray, Alicia L Bertone, Dmitri O Traktuev, Keith L March, Luis M Colon-Perez, Keith G Avin, Emily Sims, Julie A Mund, Jamie Case, Xiaolin Deng, Min Su Kim, Bruce McDavitt, Michael E Boulton, Jeffrey Thinschmidt, Sergio Li Calzi, Stephanie D Fitz, Robyn K Fuchs, Stuart J Warden, Todd McKinley, Anantha Shekhar, Marcelo Febo, Phillip L Johnson, Lung-Ji Chang, Zhanguo Gao, Mikhail G Kolonin, Song Lai, Jingfeng Ma, Xinzhong Dong, Fletcher A White, Huisheng Xie, Mervin C Yoder, Maria B Grant
Electroacupuncture (EA) performed in rats and humans using limb acupuncture sites, LI-4 and LI-11, and GV-14 and GV-20 (humans) and Bai-hui (rats) increased functional connectivity between the anterior hypothalamus and the amygdala and mobilized mesenchymal stem cells (MSCs) into the systemic circulation. In human subjects, the source of the MSC was found to be primarily adipose tissue, whereas in rodents the tissue sources were considered more heterogeneous. Pharmacological disinhibition of rat hypothalamus enhanced sympathetic nervous system (SNS) activation and similarly resulted in a release of MSC into the circulation...
May 2017: Stem Cells
https://www.readbyqxmd.com/read/28068836/electro-acupuncture-modulates-l1-adhesion-molecule-expression-after-mouse-spinal-cord-injury
#8
Zhe Wei, Yan Wang, Weijiang Zhao, Melitta Schachner
Spinal cord injury is a devastating neurological disease in desperate need of a cure. We have previously shown that overexpression of the adhesion molecule L1 contributes to locomotor recovery after injury and were therefore interested in how electro-acupuncture would influence the expression of this molecule. Here, we investigated the effects of electro-acupuncture at "Jiaji" points (EX-B2), newly established by us, in young adult mice to determine whether improved recovery via electro-acupuncture could be due to enhanced L1 expression...
2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28033308/effects-of-polysaccharide-of-gastrodia-elata-blume-and-electro-acupuncture-on-expressions-of-brain-derived-neurotrophic-factor-and-stem-cell-factor-protein-in-caudate-putamen-of-focal-cerebral-ischemia-rats
#9
Huai-Bin Li, Feng Wu, Hua-Chun Miao, Ke-Ren Xiong
BACKGROUND The aim of this study was to explore the neural protective effect of polysaccharide of Gastrodia elata Blume (PGB) and electro-acupuncture (EA) on focal cerebral ischemia rats. MATERIAL AND METHODS A total of 40 Sprague-Dawley rats were randomly divided into 5 groups (normal group, model group, PGB group, EA group and PGB+EA group). The model was prepared by middle cerebral artery occlusion (MCAO). Two week after modeling, rats were given PGB, EA, or a combination of the 2 in continuous treatment for 2 successive weeks...
December 23, 2016: Medical Science Monitor Basic Research
https://www.readbyqxmd.com/read/28010831/technical-challenges-in-current-primo-vascular-system-research-and-potential-solutions
#10
REVIEW
Kyung A Kang, Claudio Maldonado, Vitaly Vodyanoy
Since Bonghan Kim's discovery of the Bonghan system (BHS) in the 1960s, numerous reports have suggested that the system is fundamental for maintaining mammalian life. The BHS is a circulatory system independent of the blood or the lymphatic system, forms an extensive network throughout the entire mammalian body, has been reported to be the acupuncture meridian, stores distinct types of stem cells, and appears to have some roles in cancer metastasis. Despite Kim's first report having been published as early as 1962, research progress has been rather slow mainly because the system is very small and translucent, making it optically difficult to distinguish it from the hemoglobin-rich surrounding tissues...
December 2016: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/27822341/model-acupuncture-point-bone-marrow-derived-stromal-stem-cells-are-moved-by-a-weak-electromagnetic-field
#11
Artem N Emelyanov, Marina V Borisova, Vera V Kiryanova
AIM: To show the existence of a structural formative role of magnetic fields (MFs) with respect to biological objects by using our proposed model of an acupoint. METHODS: We introduced a magnetised 10-100 μT metal rod (needle) into culture dishes with a negatively charged working surface and observed during 24 h how cells were arranged by MFs and by electrical fields (EFs) when attached. Rat and human bone marrow-derived stromal stem cells (rBMSCs and hBMSCs), human nonadherent mononuclear blood cells, NCTCs and A172 cells, and Escherichia coli (E...
October 26, 2016: World Journal of Stem Cells
https://www.readbyqxmd.com/read/27634622/where-have-the-organizers-gone-the-growth-control-system-as-a-foundation-of-physiology
#12
REVIEW
Zhimin Li, Charles Shang
A model of growth control system suggests that the organizers in embryogenesis continue to exist and partially retain their function after embryogenesis. The organizers are the macroscopic singular points of the morphogen gradient and bioelectric fields. They have higher metabolic rate, higher density of gap junctions and stem cells than the surrounding tissue. The growth control model predicts that the organizers are likely to exist at the extreme points of surface or interface curvature of the body. Changes in bioelectric field at organizers precede the morphological and anatomical changes in morphogenesis and pathogenesis...
January 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/27558235/acupuncture-improves-cerebral-microenvironment-in-mice-with-alzheimer-s-disease-treated-with-hippocampal-neural-stem-cells
#13
Lan Zhao, Chunlei Zhou, Li Li, Jianwei Liu, Huiyan Shi, Bohong Kan, Zhen Li, Yunzhu Li, Jingxian Han, Jianchun Yu
Transplantation with neural stem cells (NSCs) is a promising clinical therapy for Alzheimer's disease (AD). However, the final fate of grafted NSCs is mainly determined by the host microenvironment. Therefore, this study investigated the role of Sanjiao acupuncture in the NSCs-treated hippocampus of a mouse model, senescence-accelerated mouse prone 8 (SAMP8) using Western blot, real-time fluorescent PCR, and immunofluorescence techniques. Meanwhile, we developed a co-culture model of hippocampal tissue specimens and NSCs in vitro, to observe the effects of acupuncture on survival, proliferation and differentiation of grafted NSCs using flow cytometry...
September 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/27526157/chronological-review-on-scientific-findings-of-bonghan-system-and-primo-vascular-system
#14
Kyung A Kang
In 1962, Bonghan Kim in North Korea published a report on a new vascular system in mammals, which he claimed as the acupuncture meridian. He soon named it the Bonghan System. Between 1962 and 1965, he published five reports, with detailed descriptions on the system. Kim also described the self-regenerating nature of a unique cell type Sanals in the system and these cells are now confirmed to be a type of stem cells. According to his findings, the system appears to have vital roles in maintaining mammalian lives...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27313641/acupuncture-induces-the-proliferation-and-differentiation-of-endogenous-neural-stem-cells-in-rats-with-traumatic-brain-injury
#15
Shuting Jiang, Weihao Chen, Yimin Zhang, Yujuan Zhang, Ailian Chen, Qiufu Dai, Shujun Lin, Hanyu Lin
Purpose. To investigate whether acupuncture induced the proliferation and differentiation of endogenous neural stem cells (NSCs) in a rat model of traumatic brain injury (TBI). Methods. 104 Sprague-Dawley rats were randomly divided into normal, model, and acupuncture groups. Each group was subdivided into three-day (3 d), seven-day (7 d), and fourteen-day (14 d) groups. The rat TBI model was established using Feeney's freefall epidural impact method. The rats in the acupuncture group were treated at acupoints (Baihui, Shuigou, Fengfu, Yamen, and bilateral Hegu)...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27212921/electroacupuncture-at-baihui-du20-acupoint-up-regulates-mrna-expression-of-neurod-molecules-in-the-brains-of-newborn-rats-suffering-in-utero-fetal-distress
#16
Lu Chen, Yan Liu, Qiao-Mei Lin, Lan Xue, Wei Wang, Jian-Wen Xu
NeuroD plays a key regulatory effect on differentiation of neural stem cells into mature neurons in the brain. Thus, we assumed that electroacupuncture at Baihui (DU20) acupoint in newborn rats exposed to in utero fetal distress would influence expression of NeuroD. Electroacupuncture at Baihui was performed for 20 minutes on 3-day-old (Day 3) newborn Sprague-Dawley rats exposed to in utero fetal distress; electroacupuncture parameters consisted of sparse and dense waves at a frequency of 2-10 Hz. Real-time fluorescent quantitative PCR results demonstrated that mRNA expression of NeuroD, a molecule that indicates NeuroD, increased with prolonged time in brains of newborn rats, and peaked on Day 22...
April 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/27141629/-development-of-researches-on-scalp-acupuncture-for-ischemic-stroke
#17
REVIEW
Liang Tian, Jin-hai Wang, Run-jie Sun, Xing-hua Zhang, Bo Yuan, Xiao-zheng Du
Ischemic stroke is one of the commonly met diseases in clinical practice nowadays. Acupuncture therapy is widly used in the treatment of sequela of ischemic stroke in China and its mechanisms have been extensively studied in recen years. In the present paper, the authors focus on the development of studies on the mechanism of scalp acupuncture therapy in the treatment of ischemic stroke. Results indicate that scalp acupuncture intervention can 1) improve cerebral blood circulation to promote regional energy metabolism, 2) up-regulate expression of glial cell-line derived neurotrophic factor (GDNF), etc...
February 2016: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/27082109/electro-acupuncture-promotes-endogenous-multipotential-mesenchymal-stem-cell-mobilization-into-the-peripheral-blood
#18
Lizhen Liu, Qin Yu, Kaimin Hu, Binsheng Wang, Yiran Zhang, Yulin Xu, Shan Fu, Xiaohong Yu, He Huang
BACKGROUND/AIMS: Mobilization of endogenous stem cells is an appealing strategy for cell therapy However, there is little evidence for reproducible, effective methods of mesenchymal stem cell (MSC) mobilization. In the present study, we investigated the mobilizing effect of electro-acupuncture (EA) on endogenous MSCs. METHODS: Normal adult rats were randomly divided into six groups, namely, EA for 14 days (EA14d), sham EA14d, EA21d, sham EA21d and matched control groups...
2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/26909229/faecal-incontinence-current-knowledges-and-perspectives
#19
REVIEW
Alban Benezech, Michel Bouvier, Véronique Vitton
Faecal incontinence (FI) is a disabling and frequent symptom since its prevalence can vary between 5% and 15% of the general population. It has a particular negative impact on quality of life. Many tools are currently available for the treatment of FI, from conservative measures to invasive surgical treatments. The conservative treatment may be dietetic measures, various pharmacological agents, anorectal rehabilitation, posterior tibial nerve stimulation, and transanal irrigation. If needed, patients may have miniinvasive approaches such as sacral nerve modulation or antegrade irrigation...
February 15, 2016: World Journal of Gastrointestinal Pathophysiology
https://www.readbyqxmd.com/read/26564465/-effect-of-basic-fibroblast-growth-factor-and-transforming-growth-factor-%C3%AE-1-combined-with-bone-marrow-mesenchymal-stem-cells-on-the-repair-of-degenerated-intervertebral-discs-in-rat-models
#20
Chao Jiang, Da-peng Li, Zhi-jian Zhang, Hao-ming Shu, Lang Hu, Zheng-nan Li, Yong-hui Huang
OBJECTIVE: To evaluate the effects of the combination of basic fibroblast growth factor (bFGF), transforming growth factor-Β1 (TGF-Β1), bone marrow mesenchymal stem cells (BMSCs), and temperature-responsive chitosan hydrogel (TCH) gel on the repair of degenerative intervertebral disc in rat models. METHODS: Rat models of intervertebral disc degeneration were established by acupuncture. The degenerative effects were observed under magnetic resonance imaging (MRI)...
August 2015: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
keyword
keyword
84703
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"