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https://www.readbyqxmd.com/read/28720403/gradenigo-s-syndrome-a-case-of-a-common-infection-with-uncommon-consequences
#1
Matthew Vitale, Misra Amrit, Rajan Arora, Julie Lata
Acute otitis media is a common diagnosis encountered by emergency medicine providers. With appropriate antibiotic treatment, patients with otitis media, in general, have minimal long-term sequela from their underlying infection (Limb et al., 2017 [1]). However, untreated cases can develop life-threatening complications that require prompt intervention. We report a case of an 8-year-old that developed Gradenigo's syndrome, a condition characterized by the triad of otitis media, facial pain in the distribution of the trigeminal nerve, and abducens nerve palsy (Yeung and Lustig, 2016; Janjua et al...
July 5, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28715517/ethical-considerations-for-nutrition-counseling-about-processed-food-reply
#2
Robert H Lustig
No abstract text is available yet for this article.
July 17, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28710265/francisella-like-endosymbionts-and-rickettsia-species-in-local-and-imported-hyalomma-ticks
#3
Tal Azagi, Eyal Klement, Gidon Perlman, Yaniv Lustig, Kosta Y Mumcuoglu, Dmitry Apanaskevich, Yuval Gottlieb
Hyalomma ticks (Acari: Ixodidae) are hosts for Francisella like endosymbionts (FLE) and may serve as vectors of zoonotic disease agents. This study was aimed to provide initial characterization of the interaction between Hyalomma and FLE and to determine the prevalence of pathogenic Rickettsia in these ticks. Hyalomma marginatum, H. rufipes, H. dromedarii, H. aegyptium and H. excavatum ticks, identified morphologically and molecularly, were collected from different hosts and locations, representing the genus distribution in Israel, as well as from migratory birds...
July 14, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28706270/comprehensive-multi-dimensional-mri-for-the-simultaneous-assessment-of-cardiopulmonary-anatomy-and-physiology
#4
Joseph Y Cheng, Tao Zhang, Marcus T Alley, Martin Uecker, Michael Lustig, John M Pauly, Shreyas S Vasanawala
Diagnostic testing often assesses the cardiovascular or respiratory systems in isolation, ignoring the major pathophysiologic interactions between the systems in many diseases. When both systems are assessed currently, multiple modalities are utilized in costly fashion with burdensome logistics and decreased accessibility. Thus, we have developed a new acquisition and reconstruction paradigm using the flexibility of MRI to enable a comprehensive exam from a single 5-15 min scan. We constructed a compressive-sensing approach to pseudo-randomly acquire highly subsampled, multi-dimensionally-encoded and time-stamped data from which we reconstruct volumetric cardiac and respiratory motion phases, contrast-agent dynamics, and blood flow velocity fields...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28681719/an-outbreak-of-dengue-virus-denv-type-2-cosmopolitan-genotype-in-israeli-travellers-returning-from-the-seychelles-april-2017
#5
Yaniv Lustig, Dana Wolf, Ora Halutz, Eli Schwartz
Dengue virus infection was diagnosed in six Israeli travellers returning from the Seychelles in April 2017. Phylogenetic analysis identified identical sequences belonging to the Cosmopolitan genotype of dengue virus type 2 in all samples sequenced, thus providing evidence for a probable dengue type 2 outbreak in the Seychelles. This report further demonstrates the role of travellers as sentinels for arboviral infections, especially in countries with limited diagnostic capabilities.
June 29, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28629943/arthroscopically-assisted-fixation-is-a-reliable-option-for-patellar-fractures-a-literature-review
#6
REVIEW
Simone Cerciello, Mark Cote, Sébastien Lustig, Felix Dyrna, Leo Pauzenberger, Philippe Neyret, Augustus D Mazzocca
BACKGROUND: Proper reduction and stable fixation of articular fractures is essential for an early recovery and to avoid late complications. Arthroscopically assisted techniques for minimally invasive fixation have been introduced to reduce local morbidity and improve anatomic reduction of the fragments. However up to date no clear indications for surgery have been given. In addition, the precise rates of functional outcomes and complications are controversial. The hypothesis was the systematic analysis of the available literature would provide precise indications, outcomes and complications of arthroscopically assisted techniques for patellar fracture fixation...
June 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28628400/west-nile-virus-seroprevalence-in-animals-in-palestine-and-israel
#7
Kifaya Azmi, Sharon Tirosh-Levy, Mu'taz Manasrah, Rotem Mizrahi, Abed Nasereddin, Amer Al-Jawabreh, Suheir Ereqat, Ziad Abdeen, Yaniv Lustig, Boris Gelman, Gili Schvartz, Amir Steinman
West Nile virus (WNV) epidemiological situation in Israel and Palestine, due to their unique location, draws attention following to the global spread of West Nile fever (WNF). Although much information is available from Israel on clinical cases and prevalence of WNV, clinical cases are rarely reported in Palestine, and prevalence is not known. The objectives of this study were to determine WNV seroprevalence in various domestic animals in Palestine and to reevaluate current seroprevalence, force of infection, and risk factors for WNV exposure in horses in Israel...
June 19, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28625523/induction-treatment-and-prevention-of-eczema-vaccinatum-in-atopic-dermatitis-mouse-models
#8
Hagit Achdout, Shlomo Lustig, Tomer Israely, Noam Erez, Boaz Politi, Hadas Tamir, Ofir Israeli, Trevor Waner, Sharon Melamed, Nir Paran
Eczema vaccinatum is a severe and occasionally lethal complication of smallpox vaccine, characterized by systemic viral dissemination, distant from the initial inoculation site of the vaccine. A major risk factor for eczema vaccinatum is a background of atopic dermatitis, a chronic, common allergic, relapsing disorder, manifested by dry and inflamed skin, itchy rash, Th2 biased immune response and hypersensitivity to various antigens. Unlike the severe manifestations of eczema vaccinatum in humans, current models present only mild symptoms that limits examination of potential therapeutics for eczema vaccinatum...
June 20, 2017: Vaccine
https://www.readbyqxmd.com/read/28622360/the-seroprevalence-of-west-nile-virus-in-israel-a-nationwide-cross-sectional-study
#9
Ravit Bassal, Tamy Shohat, Zalman Kaufman, Batya Mannasse, Eilat Shinar, Doron Amichay, Mira Barak, Anat Ben-Dor, Adina Bar Haim, Daniel Cohen, Ella Mendelson, Yaniv Lustig
West Nile Virus (WNV) is endemic in Israel, affecting yearly 40-160 individuals. Israel is located on a central migratory path between Africa and Eurasia and most West Nile Fever (WNF) cases reported in recent years were among residents of the coastal plain. The aim of the study was to evaluate the seroprevalence of WNV among the Israeli population and to assess correlates for WNV infection. A cross-sectional nationwide serologic survey was conducted using 3,145 serum samples collected by the national Israeli serum bank during 2011-2014, representing all age and population groups in Israel...
2017: PloS One
https://www.readbyqxmd.com/read/28579536/effects-of-dietary-fructose-restriction-on-liver-fat-de-novo-lipogenesis-and-insulin-kinetics-in-children-with-obesity
#10
Jean-Marc Schwarz, Susan M Noworolski, Ayca Erkin-Cakmak, Natalie J Korn, Michael J Wen, Viva W Tai, Grace M Jones, Sergiu P Palii, Moises Velasco-Alin, Karen Pan, Bruce W Patterson, Alejandro Gugliucci, Robert H Lustig, Kathleen Mulligan
BACKGROUND & AIMS: Consumption of sugar is associated with obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease, and cardiovascular disease. The conversion of fructose to fat in liver (de novo lipogenesis, DNL) may be a modifiable pathogenetic pathway. We determined the effect of 9 days of isocaloric fructose restriction on DNL, liver fat, visceral fat (VAT), subcutaneous fat, and insulin kinetics in obese Latino and African American children with habitual high sugar consumption (fructose intake more than 50 g/day)...
June 1, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28575907/correction-of-tibial-valgus-deformity
#11
Simone Cerciello, Sebastien Lustig, Elvire Servien, Cecile Batailler, Philippe Neyret
No abstract text is available yet for this article.
June 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/28557445/discovery-of-the-soluble-guanylate-cyclase-stimulator-vericiguat-bay-1021189-for-the-treatment-of-chronic-heart-failure
#12
Markus Follmann, Jens Ackerstaff, Gorden Redlich, Frank Wunder, Dieter Lang, Armin Kern, Peter Fey, Nils Griebenow, Walter Kroh, Eva-Maria Becker-Pelster, Axel Kretschmer, Volker Geiss, Volkhart Li, Alexander Straub, Joachim Mittendorf, Rolf Jautelat, Hartmut Schirok, Karl-Heinz Schlemmer, Klemens Lustig, Michael Gerisch, Andreas Knorr, Hanna Tinel, Thomas Mondritzki, Hubert Trübel, Peter Sandner, Johannes-Peter Stasch
The first-in-class soluble guanylate cyclase (sGC) stimulator riociguat was recently introduced as a novel treatment option for pulmonary hypertension. Despite its outstanding pharmacological profile, application of riociguat in other cardiovascular indications is limited by its short half-life, necessitating a three times daily dosing regimen. In our efforts to further optimize the compound class, we have uncovered interesting structure-activity relationships and were able to decrease oxidative metabolism significantly...
June 12, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28556180/multiple-coil-k-space-interpolation-enhances-resolution-in-single-shot-spatiotemporal-mri
#13
Gilad Liberman, Eddy Solomon, Michael Lustig, Lucio Frydman
PURPOSE: Spatio-temporal encoding (SPEN) experiments can deliver single-scan MR images without folding complications and with robustness to chemical shift and susceptibility artifacts. Further resolution improvements are shown to arise by relying on multiple receivers, to interpolate the sampled data along the low-bandwidth dimension. The ensuing multiple-sensor interpolation is akin to recently introduced SPEN interleaving procedures, albeit without requiring multiple shots. METHODS: By casting SPEN's spatial rasterization in k-space, it becomes evident that local k-data interpolations enabled by multiple receivers are akin to real-space interleaving of SPEN images...
May 28, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28555707/components-and-indicators-of-frailty-measures-a-literature-review
#14
B Xie, J L Larson, R Gonzalez, S J Pressler, C Lustig, C Arslanian-Engoren
BACKGROUND: Frailty is a debilitating condition in older adults that is associated with increased risks for adverse outcomes. However, the issue of quantifying frailty remains elusive. There is a lack of consistency in the frailty components and the corresponding indicators used to quantify these components. OBJECTIVE: 1) to describe the components of frailty and examine the existing measures of frailty; and 2) to identify current gaps in knowledge of frailty measures...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/28530330/-the-sherlock-system-clinical-and-logistic-pharmaceutical-services
#15
Roni Leibowitz, Shahar Aflalo, Ornit Cohen, Ahuva Lustig
BACKGROUND: The drug inventory in the hospital consumes a large part of the hospital's budget. Classic drug management is based on weekly visits of the pharmacist in the departments, writing an order and dispensing it. This method is wasteful in terms of sending a bulk of drugs that will not necessarily be utilized, and it is also inefficient in terms of human resources. The unit-dose method, which is more advanced, is based on filling out individual prescriptions for each of the inpatients in the department...
August 2016: Harefuah
https://www.readbyqxmd.com/read/28487165/west-nile-virus-outbreak-in-israel-in-2015-phylogenetic-and-geographic-characterization-in-humans-and-mosquitoes
#16
Yaniv Lustig, Zalman Kaufman, Batya Mannasse, Ravit Koren, Shiri Katz-Likvornik, Laor Orshan, Aharona Glatman-Freedman, Ella Mendelson
OBJECTIVES: West Nile Virus (WNV) is endemic in Israel and was responsible for several outbreaks in the past 16 years. The aim of the present study was to investigate the spatial distribution of WNV acute infections from an outbreak which occurred in 2015 in Israel and report the molecular and geographic characterization of WNV isolates from human cases and mosquito pools obtained during this outbreak. METHODS: Using a geographical layer comprising 51 continuous areas of Israel, the number of WNV infection cases per 100,000 people in each area and the locations of WNV-infected mosquitoes in 2015 were analyzed...
May 6, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28475039/correction-intracellular-growth-of-mycobacterium-tuberculosis-after-macrophage-cell-death-leads-to-serial-killing-of-host-cells
#17
Deeqa Mahamed, Mikael Boulle, Yashica Ganga, Chanelle Mc Arthur, Steven Skroch, Lance Oom, Oana Catinas, Kelly Pillay, Myshnee Naicker, Sanisha Rampersad, Colisile Mathonsi, Jessica Hunter, Emily B Wong, Moosa Suleman, Gopalkrishna Sreejit, Alexander S Pym, Gila Lustig, Alex Sigal
No abstract text is available yet for this article.
May 5, 2017: ELife
https://www.readbyqxmd.com/read/28462954/metal-organic-frameworks-functional-luminescent-and-photonic-materials-for-sensing-applications
#18
REVIEW
William P Lustig, Soumya Mukherjee, Nathan D Rudd, Aamod V Desai, Jing Li, Sujit K Ghosh
Metal-organic frameworks (MOFs) or porous coordination polymers (PCPs) are open, crystalline supramolecular coordination architectures with porous facets. These chemically tailorable framework materials are the subject of intense and expansive research, and are particularly relevant in the fields of sensory materials and device engineering. As the subfield of MOF-based sensing has developed, many diverse chemical functionalities have been carefully and rationally implanted into the coordination nanospace of MOF materials...
June 6, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28450978/beyond-low-rank-sparse-multi-scale-low-rank-matrix-decomposition
#19
Frank Ong, Michael Lustig
We present a natural generalization of the recent low rank + sparse matrix decomposition and consider the decomposition of matrices into components of multiple scales. Such decomposition is well motivated in practice as data matrices often exhibit local correlations in multiple scales. Concretely, we propose a multi-scale low rank modeling that represents a data matrix as a sum of block-wise low rank matrices with increasing scales of block sizes. We then consider the inverse problem of decomposing the data matrix into its multi-scale low rank components and approach the problem via a convex formulation...
June 2016: IEEE Journal of Selected Topics in Signal Processing
https://www.readbyqxmd.com/read/28446371/beware-of-the-toilet-the-risk-for-a-deep-tissue-injury-during-toilet-sitting
#20
Maayan Lustig, Ayelet Levy, Kara Kopplin, Zehava Ovadia-Blechman, Amit Gefen
A pressure injury (PrI) compromises quality of life and can be life-threatening. The fundamental cause of PrIs is sustained deformations in weight-bearing soft tissues, e.g., during prolonged sitting on inadequate surfaces such as a toilet seat. In nursing homes and geriatric facilities, patients need assistance using the restroom, and patients being left on the toilet for tens-of-minutes is a real-world scenario, unfortunately. Nevertheless, there are no published studies regarding sustained tissue loads during toilet sitting and their effects on tissue physiology...
April 23, 2017: Journal of Tissue Viability
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