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https://www.readbyqxmd.com/read/28530330/-the-sherlock-system-clinical-and-logistic-pharmaceutical-services
#1
Roni Leibowitz, Shahar Aflalo, Ornit Cohen, Ahuva Lustig
BACKGROUND: The drug inventory in the hospital consumes a large part of the hospital's budget. Classic drug management is based on weekly visits of the pharmacist in the departments, writing an order and dispensing it. This method is wasteful in terms of sending a bulk of drugs that will not necessarily be utilized, and it is also inefficient in terms of human resources. The unit-dose method, which is more advanced, is based on filling out individual prescriptions for each of the inpatients in the department...
August 2016: Harefuah
https://www.readbyqxmd.com/read/28487165/west-nile-virus-outbreak-in-israel-in-2015-phylogenetic-and-geographic-characterization-in-humans-and-mosquitoes
#2
Yaniv Lustig, Zalman Kaufman, Batya Mannasse, Ravit Koren, Shiri Katz-Likvornik, Laor Orshan, Aharona Glatman-Freedman, Ella Mendelson
OBJECTIVES: West Nile Virus (WNV) is endemic in Israel and was responsible for several outbreaks in the past 16 years. The aim of the present study was to investigate the spatial distribution of WNV acute infections from an outbreak which occurred in 2015 in Israel and report the molecular and geographic characterization of WNV isolates from human cases and mosquito pools obtained during this outbreak. METHODS: Using a geographical layer comprising 51 continuous areas of Israel, the number of WNV infection cases per 100,000 people in each area and the locations of WNV-infected mosquitoes in 2015 were analyzed...
May 6, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28475039/correction-intracellular-growth-of-mycobacterium-tuberculosis-after-macrophage-cell-death-leads-to-serial-killing-of-host-cells
#3
Deeqa Mahamed, Mikael Boulle, Yashica Ganga, Chanelle Mc Arthur, Steven Skroch, Lance Oom, Oana Catinas, Kelly Pillay, Myshnee Naicker, Sanisha Rampersad, Colisile Mathonsi, Jessica Hunter, Emily B Wong, Moosa Suleman, Gopalkrishna Sreejit, Alexander S Pym, Gila Lustig, Alex Sigal
No abstract text is available yet for this article.
May 5, 2017: ELife
https://www.readbyqxmd.com/read/28462954/metal-organic-frameworks-functional-luminescent-and-photonic-materials-for-sensing-applications
#4
REVIEW
William P Lustig, Soumya Mukherjee, Nathan D Rudd, Aamod V Desai, Jing Li, Sujit K Ghosh
Metal-organic frameworks (MOFs) or porous coordination polymers (PCPs) are open, crystalline supramolecular coordination architectures with porous facets. These chemically tailorable framework materials are the subject of intense and expansive research, and are particularly relevant in the fields of sensory materials and device engineering. As the subfield of MOF-based sensing has developed, many diverse chemical functionalities have been carefully and rationally implanted into the coordination nanospace of MOF materials...
May 2, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28450978/beyond-low-rank-sparse-multi-scale-low-rank-matrix-decomposition
#5
Frank Ong, Michael Lustig
We present a natural generalization of the recent low rank + sparse matrix decomposition and consider the decomposition of matrices into components of multiple scales. Such decomposition is well motivated in practice as data matrices often exhibit local correlations in multiple scales. Concretely, we propose a multi-scale low rank modeling that represents a data matrix as a sum of block-wise low rank matrices with increasing scales of block sizes. We then consider the inverse problem of decomposing the data matrix into its multi-scale low rank components and approach the problem via a convex formulation...
June 2016: IEEE Journal of Selected Topics in Signal Processing
https://www.readbyqxmd.com/read/28446371/beware-of-the-toilet-the-risk-for-a-deep-tissue-injury-during-toilet-sitting
#6
Maayan Lustig, Ayelet Levy, Kara Kopplin, Zehava Ovadia-Blechman, Amit Gefen
A pressure injury (PrI) compromises quality of life and can be life-threatening. The fundamental cause of PrIs is sustained deformations in weight-bearing soft tissues, e.g., during prolonged sitting on inadequate surfaces such as a toilet seat. In nursing homes and geriatric facilities, patients need assistance using the restroom, and patients being left on the toilet for tens-of-minutes is a real-world scenario, unfortunately. Nevertheless, there are no published studies regarding sustained tissue loads during toilet sitting and their effects on tissue physiology...
April 23, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28426902/hepatic-steatosis-after-pediatric-liver-transplant
#7
Emily R Perito, Tabitha Vase, Rageshree Ramachandran, Andrew Phelps, Kuang-Yu Jen, Robert H Lustig, Vickie A Feldstein, Philip Rosenthal
RATIONALE: Hepatic steatosis develops after liver transplant in 30% of adults, and non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in non-transplanted children. However, post-transplant steatosis has been minimally studied in pediatric liver transplant recipients. We explored the prevalence, persistence, and association with chronic liver damage of hepatic steatosis in these children. RESULTS: In this single-center study of pediatric patients transplanted 1988-2015 (n=318), 31% of those with any post-transplant biopsy (n=271) had ≥1 biopsy with steatosis...
April 20, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28402779/mechanisms-pathophysiology-and-management-of-obesity
#8
LETTER
Florian L Stigler, Robert H Lustig, Janet I Ma
No abstract text is available yet for this article.
April 13, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28396931/does-low-constraint-mobile-bearing-knee-prosthesis-give-satisfactory-results-for-severe-coronal-deformities-a-five-to-twelve-year-follow-up-study
#9
Jaroslaw Czekaj, Camdon Fary, Thierry Gaillard, Sebastien Lustig
PURPOSE: Severe varus and valgus knee deformities traditionally are replaced with constrained implants, with a number of disadvantages. We present our results in this challenging group using a low constraint deep-dish mobile bearing implant design. METHODS: One hundred fifty-four patients (170 arthroplasties) who underwent primary TKA using a deep-dish, mobile bearing posterior-stabilized implant for severe varus (HKA < 170°) or valgus (HKA > 190°) deformity between 2004 and 2009 were evaluated at a mean of 6...
April 11, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28381608/sensitivity-and-kinetics-of-a-ns1-based-zika-virus-elisa-in-zika-infected-travelers-from-israel-czech-republic-italy-belgium-germany-and-chile
#10
Yaniv Lustig, Hana Zelena, Giulietta Venturi, Marjan Van Esbroeck, Camilla Rothe, Cecilia Perret, Ravit Koren, Shiri Katz-Likvornik, Ella Mendelson, Eli Schwartz
Serological diagnosis of Zika Virus is challenging due to high cross-reactivity of Zika virus with other flavivirus antibodies. Recently, a Zika-NS1 based ELISA was developed and shown to be highly specific for Zika antibodies detection; however, sensitivity was evaluated for only a small number of confirmed Zika infected patients. In this study we measured the sensitivity and kinetics of Zika IgM and IgG antibodies by the Zika-NS1 based ELISA in 105 samples from 63 returning-travelers infected by Zika virus (proven by PCR or neutralization assay) from Israel, Czech-Republic, Italy, Belgium, Germany and Chile...
April 5, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28321477/total-knee-arthroplasty-after-varus-distal-femoral-osteotomy-vs-native-knee-similar-results-in-a-case-control-study
#11
Romain Gaillard, Timothy Lording, Sebastien Lustig, Elvire Servien, Philippe Neyret
PURPOSE: The aim of this study was to investigate the results of total knee arthroplasty (TKA) performed after varus distal femoral osteotomy (VrDFO), in comparison to a control group of TKAs performed as the primary intervention for arthrosis. Main hypothesis was that the medium term results for the two groups would be similar. METHODS: All TKAs performed after VrDFO were extracted from a single centre, prospective database of 4046 arthroplasties. A case-control study was performed with a control group comprising two TKAs performed as the primary intervention for each TKA after VrDFO, and matched for sex, age at intervention, body mass index, the type of arthrosis and the type of implant...
March 20, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28320361/estimates-of-hospitalization-attributable-to-influenza-and-rsv-in-the-us-during-1997-2009-by-age-and-risk-status
#12
Gonçalo Matias, Robert Taylor, François Haguinet, Cynthia Schuck-Paim, Roger Lustig, Vivek Shinde
BACKGROUND: Estimates of influenza and respiratory syncytial virus (RSV) burden must be periodically updated to inform public health strategies. We estimated seasonal influenza- and RSV-attributable hospitalizations in the US from 1997 to 2009 according to age and risk status (NCT01599390). METHODS: Multiple linear regression modelling was used to attribute hospitalizations to influenza or RSV using virological surveillance and hospitalization data. Hospitalization data were obtained from the US Nationwide Inpatient Sample and virology data were obtained from FluView (Centers for Disease Control and Prevention)...
March 21, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28280753/mouse-auditory-brainstem-response-testing
#13
Omar Akil, A E Oursler, Kevin Fan, Lawrence R Lustig
The auditory brainstem response (ABR) test provides information about the inner ear (cochlea) and the central pathways for hearing. The ABR reflects the electrical responses of both the cochlear ganglion neurons and the nuclei of the central auditory pathway to sound stimulation (Zhou et al., 2006; Burkard et al., 2007). The ABR contains 5 identifiable wave forms, labeled as I-V. Wave I represents the summated response from the spiral ganglion and auditory nerve while waves II-V represent responses from the ascending auditory pathway...
March 20, 2016: Bio-protocol
https://www.readbyqxmd.com/read/28260693/genomic-deletion-of-git2-induces-a-premature-age-related-thymic-dysfunction-and-systemic-immune-system-disruption
#14
Sana Siddiqui, Ana Lustig, Arnell Carter, Mathavi Sankar, Caitlin M Daimon, Richard T Premont, Harmonie Etienne, Jaana van Gastel, Abdelkrim Azmi, Jonathan Janssens, Kevin G Becker, Yongqing Zhang, William Wood, Elin Lehrmann, James G Martin, Bronwen Martin, Dennis D Taub, Stuart Maudsley
Recent research has proposed that GIT2 (G protein-coupled receptor kinase interacting protein 2) acts as an integrator of the aging process through regulation of 'neurometabolic' integrity. One of the commonly accepted hallmarks of the aging process is thymic involution. At a relatively young age, 12 months old, GIT2(-/-) mice present a prematurely distorted thymic structure and dysfunction compared to age-matched 12 month-old wild-type control (C57BL/6) mice. Disruption of thymic structure in GIT2(-/-) (GIT2KO) mice was associated with a significant reduction in the expression of the cortical thymic marker, Troma-I (cytokeratin 8)...
March 4, 2017: Aging
https://www.readbyqxmd.com/read/28253080/distinct-frontoparietal-networks-underlying-attentional-effort-and-cognitive-control
#15
Anne S Berry, Martin Sarter, Cindy Lustig
We investigated the brain activity patterns associated with stabilizing performance during challenges to attention. Our findings revealed distinct patterns of frontoparietal activity and functional connectivity associated with increased attentional effort versus preserved performance during challenged attention. Participants performed a visual signal detection task with and without presentation of a perceptual-attention challenge (changing background). The challenge condition increased activation in frontoparietal regions including right mid-dorsal/dorsolateral pFC (RPFC), approximating Brodmann's area 9, and superior parietal cortex...
March 2, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28213703/proximal-tibial-bony-and-meniscal-slopes-are-higher-in-acl-injured-subjects-than-controls-a-comparative-mri-study
#16
Ashraf Elmansori, Timothy Lording, Raphaël Dumas, Khalifa Elmajri, Philippe Neyret, Sébastien Lustig
PURPOSE: Increased tibial slope is reported as a risk factor of non-contact anterior cruciate ligament (ACL) injury, but the effect of the soft tissues on slope remains unclear. The primary aims of this study were to compare the tibial bony and soft tissue slopes between patients with and without ACL injury, and to investigate the relationship between the meniscal slopes (MS) and the tibial bony slope. Our hypothesis was that the menisci would correct the inclination of the bony tibial slope towards the horizontal...
February 17, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28167688/implant-associated-esbl-klebsiella-pneumonia-producing-small-colony-variant-bone-and-joint-infection-in-a-healthy-40-year-old-man
#17
Cécile Ronde-Oustau, Sébastien Lustig, Céline Dupieux, Tristan Ferry
No abstract text is available yet for this article.
February 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28167350/thalamic-cholinergic-innervation-makes-a-specific-bottom-up-contribution-to-signal-detection-evidence-from-parkinson-s-disease-patients-with-defined-cholinergic-losses
#18
Kamin Kim, Martijn L T M Müller, Nicolaas I Bohnen, Martin Sarter, Cindy Lustig
Successful behavior depends on the ability to detect and respond to relevant cues, especially under challenging conditions. This essential component of attention has been hypothesized to be mediated by multiple neuromodulator systems, but the contributions of individual systems (e.g., cholinergic, dopaminergic) have remained unclear. The present study addresses this issue by leveraging individual variation in regionally-specific cholinergic denervation in Parkinson's disease (PD) patients, while controlling for variation in dopaminergic denervation...
April 1, 2017: NeuroImage
https://www.readbyqxmd.com/read/28162663/-421-a-novel-non-opioid-conesnail-peptide-based-analgesic-as-a-therapeutic-alternative-for-the-treatment-of-chronic-pain
#19
J Mercado, M Xu, K Norton, D Peckham, J Posakony, E Tarcha, J Bartron, M Brown, K Lustig, L Manelli, C Ghelardini, B Cheppudira, M Fowler, S Christensen, J McIntosh, S Iadonato
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28160060/does-a-third-condyle-tka-restore-normal-gait-kinematics-in-varus-knees-in-vivo-knee-kinematic-analysis
#20
Dafina Bytyqi, Bujar Shabani, Laurence Cheze, Philippe Neyret, Sebastien Lustig
INTRODUCTION: Patients with knee osteoarthritis tend to modify spatial and temporal parameters during walking to reduce the pain. Total knee arthroplasty (TKA) is considered the gold standard treatment for end-stage knee osteoarthritis. However, reduced physical function of the knee is partly, but apparently not fully, remedied by surgery. The purpose of this study was to investigate the in vivo, three dimensional knee kinematics during gait at the patients with knee osteoarthritis and the influence of "third condyle" psoterior stabilized (PS) total knee arthroplasty on restoration of normal kinematics...
February 3, 2017: Archives of Orthopaedic and Trauma Surgery
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