Georg Seifert, Sarah B Blakeslee, Gabriele Calaminus, Farid I Kandil, Andrea Barth, Toralf Bernig, Carl Friedrich Classen, Selim Corbacioglu, Jürgen Föll, Sven Gottschling, Bernd Gruhn, Claudia Vom Hoff-Heise, Holger N Lode, David Martin, Michaela Nathrath, Felix Neunhoeffer, Arnulf Pekrun, Beate Wulff, Tycho Zuzak, Günter Henze, Alfred Längler
BACKGROUND: Integrative medicine is used frequently alongside chemotherapy treatment in pediatric oncology, but little is known about the influence on toxicity. This German, multi-center, open-label, randomized controlled trial assessed the effects of complementary treatments on toxicity related to intensive-phase chemotherapy treatment in children aged 1-18 with the primary outcome of the toxicity sum score. Secondary outcomes were chemotherapy-related toxicity, overall and event-free survival after 5 years in study patients...
June 13, 2022: BMC Cancer