keyword
https://read.qxmd.com/read/38507481/longitudinal-intravital-imaging-of-mouse-placenta
#1
JOURNAL ARTICLE
Xiaoyi Zhu, Qiang Huang, Laiming Jiang, Van-Tu Nguyen, Tri Vu, Garth Devlin, Jabbar Shaima, Xiaobei Wang, Yong Chen, Lijun Ma, Kun Xiang, Ergang Wang, Qiangzhou Rong, Qifa Zhou, Yubin Kang, Aravind Asokan, Liping Feng, Shiao-Wen D Hsu, Xiling Shen, Junjie Yao
Studying placental functions is crucial for understanding pregnancy complications. However, imaging placenta is challenging due to its depth, volume, and motion distortions. In this study, we have developed an implantable placenta window in mice that enables high-resolution photoacoustic and fluorescence imaging of placental development throughout the pregnancy. The placenta window exhibits excellent transparency for light and sound. By combining the placenta window with ultrafast functional photoacoustic microscopy, we were able to investigate the placental development during the entire mouse pregnancy, providing unprecedented spatiotemporal details...
March 22, 2024: Science Advances
https://read.qxmd.com/read/38498256/concurrent-spontaneous-coronary-dissection-and-reversible-cerebral-vasoconstriction-syndrome-during-postnatal-care
#2
JOURNAL ARTICLE
Sang Gon Yoon, Yeo-Jeong Song, Yun-Seok Song, Jino Park, Seunghwan Kim, Dong-Kie Kim, Ki-Hun Kim, Doo-Il Kim, Hyun Kuk Kim, Dong Ah Lee
BACKGROUND: Pregnancy-associated spontaneous coronary artery dissection (SCAD) and reversible cerebral vasoconstriction syndrome (RCVS) are rare conditions that may occur during pregnancy and the postpartum period. The coexistence of both diseases may pose a risk to patients, potentially resulting in a variety of complications and clinical manifestations. This is considered the first case of a patient who successfully recovered from a critical condition in the postpartum period, with contemporaneous SCAD and RCVS...
March 18, 2024: Egyptian Heart Journal: EHJ
https://read.qxmd.com/read/38487376/neo-adjuvant-methotrexate-to-aid-minimally-invasive-surgery-in-cervical-ectopic-pregnancy-a-case-report
#3
Matteo Di Carlofelice, Danica Vress
Cervical ectopic pregnancies account for <1% of ectopic pregnancies. Early diagnosis may reduce the morbidity and mortality associated with treatment. A 43-year-old woman, gravida 4 para 2, presented at 5 + 6 weeks of gestation of pregnancy via in vitro fertilisation with painless vaginal bleeding. Her initial serum β-hCG level was 51,495 mIU/mL. Ultrasound showed a live ectopic pregnancy within the upper cervical canal with no sliding sign. Surgery was avoided initially due to risk of haemorrhage...
March 2024: Case Reports in Women's Health
https://read.qxmd.com/read/38460826/cardiovascular-and-obstetric-outcomes-among-delivering-patients-with-marfan-or-loeys-dietz-syndrome-a-retrospective-analysis-by-hospital-delivery-setting
#4
JOURNAL ARTICLE
Dr Anna R Whelan, Dr Margaret M Thorsen, Ms Gretchen Maccarrick, Dr Melissa L Russo
BACKGROUND: Pregnancy is a high-risk time for patients with Marfan syndrome (MFS) or Loeys-Dietz (LDS) syndrome due to risk for cardiovascular complications including risk of aortic dissection. Little is known about differences in obstetric and cardiac outcomes based on delivery hospital setting (academic/academic-affiliated versus community medical centers). OBJECTIVE: This study aimed to evaluate obstetric and cardiac outcomes of patients with MFS or LDS based on delivery hospital setting...
March 7, 2024: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/38445487/compression-only-or-standard-cardiopulmonary-resuscitation-for-trained-laypersons-in-out-of-hospital-cardiac-arrest-a-nationwide-randomized-trial-in-sweden
#5
JOURNAL ARTICLE
Gabriel Riva, Erik Boberg, Mattias Ringh, Martin Jonsson, Andreas Claesson, Anette Nord, Sten Rubertsson, Hans Blomberg, Per Nordberg, Sune Forsberg, Mårten Rosenqvist, Leif Svensson, Cecilia Andréll, Johan Herlitz, Jacob Hollenberg
BACKGROUND: The ongoing TANGO2 (Telephone Assisted CPR. AN evaluation of efficacy amonGst cOmpression only and standard CPR) trial is designed to evaluate whether compression-only cardiopulmonary resuscitation (CPR) by trained laypersons is noninferior to standard CPR in adult out-of-hospital cardiac arrest. This pilot study assesses feasibility, safety, and intermediate clinical outcomes as part of the larger TANGO2 survival trial. METHODS: Emergency medical dispatch calls of suspected out-of-hospital cardiac arrest were screened for inclusion at 18 dispatch centers in Sweden between January 1, 2017, and March 12, 2020...
March 6, 2024: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/38373497/-maternal-mortality-due-to-venous-thromboembolism-in-france-2016-2018
#6
JOURNAL ARTICLE
Marie Jonard, Mathias Rossignol, Coralie Chiesa-Dubruille
Pregnancy and the postpartum period represent a thromboembolic risk situation, with pulmonary embolism (PE) remaining one of the leading causes of direct maternal deaths in developed countries. Between 2016 and 2018 in France, twenty maternal deaths were caused by venous thromboembolic complications (VTE), yielding a Maternal Mortality Ratio (MMR) of 0.9 per 100,000 live births (95% CI 0.6-1.3), with no change compared to the periods 2013-2015 or 2010-2012. Among these 20 deaths, 1 death was related to cerebral thrombophlebitis, and the remaining 19 were due to PE...
February 17, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38373488/-maternal-deaths-and-management-by-emergency-departments-in-france-2016-2018
#7
JOURNAL ARTICLE
Mathias Rossignol, Eric Verspyck, Marie Jonard
In France, 272 maternal deaths occurred during the period 2016-2018, of which 131 were initially treated by healthcare professionals not specialized in obstetric. Fifty-six files were excluded because they did not concern emergency services or because there was insufficient data to allow analysis. Seventy-five cases of maternal deaths initially treated by emergency services (in-hospital emergency department (ED) or emergency medical ambulance (SAMU)) were analyzed. Fifty-six cases were treated by the SAMU and 22 by an ED (both in 3 cases)...
February 17, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38355477/intravenous-lipid-emulsion-for-local-anaesthetic-systemic-toxicity-in-pregnant-women-a-scoping-review
#8
REVIEW
Makoto Tsuji, Masafumi Nii, Marie Furuta, Shinji Baba, Takahide Maenaka, Shigetaka Matsunaga, Hiroaki Tanaka, Atsushi Sakurai
BACKGROUND: Local anaesthetic systemic toxicity (LAST) is a rare but life-threatening complication that can occur after local anaesthetic administration. Various clinical guidelines recommend an intravenous lipid emulsion as a treatment for local anaesthetic-induced cardiac arrest. However, its therapeutic application in pregnant patients has not yet been established. This scoping review aims to systematically identify and map the evidence on the efficacy and safety of intravenous lipid emulsion for treating LAST during pregnancy...
February 14, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38264914/2024-heart-disease-and-stroke-statistics-a-report-of-us-and-global-data-from-the-american-heart-association
#9
REVIEW
Seth S Martin, Aaron W Aday, Zaid I Almarzooq, Cheryl A M Anderson, Pankaj Arora, Christy L Avery, Carissa M Baker-Smith, Bethany Barone Gibbs, Andrea Z Beaton, Amelia K Boehme, Yvonne Commodore-Mensah, Maria E Currie, Mitchell S V Elkind, Kelly R Evenson, Giuliano Generoso, Debra G Heard, Swapnil Hiremath, Michelle C Johansen, Rizwan Kalani, Dhruv S Kazi, Darae Ko, Junxiu Liu, Jared W Magnani, Erin D Michos, Michael E Mussolino, Sankar D Navaneethan, Nisha I Parikh, Sarah M Perman, Remy Poudel, Mary Rezk-Hanna, Gregory A Roth, Nilay S Shah, Marie-Pierre St-Onge, Evan L Thacker, Connie W Tsao, Sarah M Urbut, Harriette G C Van Spall, Jenifer H Voeks, Nae-Yuh Wang, Nathan D Wong, Sally S Wong, Kristine Yaffe, Latha P Palaniappan
BACKGROUND: The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, and obesity) and health factors (cholesterol, blood pressure, glucose control, and metabolic syndrome) that contribute to cardiovascular health. The AHA Heart Disease and Stroke Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, brain health, complications of pregnancy, kidney disease, congenital heart disease, rhythm disorders, sudden cardiac arrest, subclinical atherosclerosis, coronary heart disease, cardiomyopathy, heart failure, valvular disease, venous thromboembolism, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs)...
January 24, 2024: Circulation
https://read.qxmd.com/read/38249261/early-versus-late-initiation-of-hydrocortisone-in-patients-with-septic-shock-a-prospective-study
#10
JOURNAL ARTICLE
Moath Alsulami, Lamees Alrojaie, Abubker Omaer
Introduction The optimal timing of corticosteroid initiation in septic shock patients is debatable. The Surviving Sepsis Campaign Guidelines recommended adding hydrocortisone to septic shock patients who require a vasopressor with a dose of norepinephrine ≥ 0.25 mcg/kg/min for at least four hours. Nevertheless, the best time to initiate hydrocortisone remains uncertain. Objective Assessing the impact of early (≤3 hours) versus late (>3 hours) initiation of hydrocortisone in septic patients...
December 2023: Curēus
https://read.qxmd.com/read/38214064/preventing-maternal-cardiac-arrest-how-do-we-reach-the-next-level-of-safety-in-obstetric-anaesthesia
#11
EDITORIAL
D T Monks, P M Singh, A Palanisamy
No abstract text is available yet for this article.
January 12, 2024: Anaesthesia
https://read.qxmd.com/read/38187217/massive-hemoptysis-in-pregnancy-treated-by-ecmo-combined-with-electronic-bronchoscopy-a-case-report
#12
Keyu Li, Long Wen, Haibo Zhou, Zhiguo Zhou
BACKGROUND: Massive hemoptysis during pregnancy is very rare. Dieulafoy's disease is one of the causes of massive hemoptysis. There are few reports of ECMO use to treat massive hemoptysis during pregnancy. FINDINGS: We report for the first time a patient with Dieulafoy's disease diagnosed at 29 weeks of pregnancy. The patient's hemoptysis occurred rapidly with large volumes. The bleeding amount reached 500 ml within half an hour, with the development of asphyxia and respiratory and cardiac arrest due to a blood clot blocking the airway...
January 15, 2024: Heliyon
https://read.qxmd.com/read/38184536/maternal-near-miss-as-a-predictor-of-adverse-perinatal-outcomes-findings-from-a-prospective-cohort-study-in-southwestern-uganda
#13
JOURNAL ARTICLE
Mark Jjuuko, Henry Mark Lugobe, Richard Migisha, David Collins Agaba, Leevan Tibaijuka, Musa Kayondo, Joseph Ngonzi, Paul Kato Kalyebara, Hamson Kanyesigye
BACKGROUND: Despite efforts, Uganda has not met the World Health Organization target of < 12 newborn deaths per 1,000 live births. Severe maternal morbidity or 'near miss' is a major contributor to adverse perinatal outcomes, particularly in low-resource settings. However, the specific impact of maternal near miss on perinatal outcomes in Uganda remains insufficiently investigated. We examined the association between maternal near miss and adverse perinatal outcomes at Mbarara Regional Referral Hospital (MRRH) in southwestern Uganda...
January 6, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38155718/clinical-application-of-single-nucleotide-polymorphism-microarray-analysis-in-pregnancy-loss-in-northwest-china
#14
JOURNAL ARTICLE
ShuYuan Xue, LiXia Wang, Jie Wei, YuTong Liu, GuiFeng Ding, PengGao Dai
Background: Spontaneous abortion is the most common complication of early pregnancy. In this study, we aim to investigate the clinical application value of genetic diagnosis using single nucleotide polymorphism (SNP) microarray analysis on the products of conception and to characterize the types of genetic abnormalities and their prevalence in pregnancy loss in Northwest China. Methods: Over 48 months, we selected 652 products of conception, which included chorionic villi, fetal tissues, germ cell samples, amniotic fluid samples, cord blood samples, and a cardiac blood sample...
2023: Frontiers in Genetics
https://read.qxmd.com/read/38094734/intrapartum-management-in-maternal-brugada-syndrome
#15
Helena Y Hong, Gina F Milone, Jaber J Hanhan, Brittany File, Afshan B Hameed
Brugada syndrome is a genetic cardiac disease associated with increased risk of ventricular tachyarrhythmia and sudden cardiac arrest. Labor and delivery in this population poses management challenges of labor induction, analgesia, postpartum hemorrhage, and arrhythmic events. This case report describes a multidisciplinary approach to intrapartum management in maternal Brugada syndrome.
December 6, 2023: JACC. Case reports
https://read.qxmd.com/read/38094732/successful-pregnancy-after-cardiac-arrest-in-a-woman-with-severe-coronary%C3%A2-vasospasm
#16
Thara S Ali, Ashley K Russell, Yuliya Paulenka, Emily R Baker, Leigh C Hickerson, Cynthia C Taub, Kerrilynn C Hennessey
A 37-year-old gravida 5, para 3 woman presented with an unplanned pregnancy 6 weeks after experiencing a cardiac arrest caused by ventricular fibrillation from coronary vasospasm. She opted to continue the pregnancy with medical management despite ongoing chest pain and delivered a healthy female infant via vaginal delivery at 37 weeks.
December 6, 2023: JACC. Case reports
https://read.qxmd.com/read/38086577/uterine-rupture-of-an-unscarred-gravid-uterus-at-term-attributed-to-adenomyosis
#17
JOURNAL ARTICLE
Lucy Phillips, Heather Brown, Anthony Williams
Uterine rupture is a rare obstetric emergency that is typically associated with the presence of scar tissue such as in the case of previous caesarean section. In this case report, a primigravid patient presented to the hospital in cardiac arrest with massive haemoperitoneum secondary to a posterior uterine rupture. The histological specimen was found to have diffuse adenomyosis at the site of rupture. On review of the literature, there is insufficient evidence to suggest we as clinicians should alter the antenatal care for patients with known adenomyosis; however, this case highlights how we should have a high index of suspicion for those presenting with signs and symptoms of uterine rupture with known adenomyosis in the absence of other risk factors...
December 12, 2023: BMJ Case Reports
https://read.qxmd.com/read/38047601/extracorporeal-cardiopulmonary-resuscitation-for-amniotic-fluid-embolism-review-and-case-report
#18
REVIEW
Courtney Stanley Sundin, Laura Gomez, Brian Chapman
Amniotic fluid embolism (AFE) is a rare, sudden, and catastrophic complication of pregnancy that can result in cardiopulmonary arrest, potentially leading to death. The pathophysiology of an AFE includes an inflammatory and coagulopathic response due to fetal materials entering maternal circulation with the hallmark triad of symptoms: acute respiratory distress, cardiovascular collapse, and coagulopathy. Management of AFE should include high-quality cardiopulmonary resuscitation, immediate delivery of the fetus if applicable, early intubation to provide adequate oxygenation and ventilation, fluid volume resuscitation, and ongoing evaluation of coagulopathy...
January 2024: MCN. the American Journal of Maternal Child Nursing
https://read.qxmd.com/read/37948872/peripartum-cardiomyopathy-delivery-hospitalization-and-postpartum-readmission-trends-risk-factors-and-outcomes
#19
JOURNAL ARTICLE
Hooman Azad, Timothy Wen, Natalie A Bello, Whitney A Booker, Stephanie Purisch, Mary E D'Alton, Alexander M Friedman
OBJECTIVE: To evaluate risk for peripartum cardiomyopathy during delivery and postpartum hospitalizations, and analyze associated trends, risk factors, and clinical outcomes. METHODS: The 2010-2020 Nationwide Readmissions Database was used for this retrospective cohort study. Delivery hospitalizations along with postpartum readmissions occurring within five months of delivery discharge were analyzed. Risk factors associated with peripartum cardiomyopathy were analyzed with unadjusted and adjusted logistic regression models with odds ratios as measures of effect...
November 8, 2023: Pregnancy Hypertension
https://read.qxmd.com/read/37923244/characterization-of-cardiac-arrhythmias-and-maternal-fetal-outcomes-in-pregnant-women-a-prospective-cohort-study
#20
JOURNAL ARTICLE
Edison Muñoz-Ortiz, Andrés Felipe Miranda-Arboleda, Yesid Alberto Saavedra-González, Jairo Alfonso Gándara-Ricardo, Jesús Velásquez-Penagos, Natalia Giraldo-Ardila, Magnolia Zapata-Montoya, Erica Holguín-Gonzalez, Francisco Villegas-García, Juan Manuel Senior-Sanchez
INTRODUCTION AND OBJECTIVES: Cardiovascular disease is a common cause of morbidity and mortality in pregnant women. Arrhythmias are common complications during pregnancy; however, the data are limited. Our goal was to characterize the epidemiology, clinical presentation, and impact of cardiac arrhythmias on maternal-fetal outcomes. METHODS: A prospective cohort study from the Colombian Registry of Pregnancy and Cardiovascular Disease was carried out from 2016 to 2019...
November 3, 2023: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
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