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American Stroke Association

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https://www.readbyqxmd.com/read/29459394/hyperintense-vessels-collateralization-and-functional-outcome-in-patients-with-stroke-receiving-endovascular-treatment
#1
Alexander H Nave, Anna Kufner, Philipp Bücke, Eberhard Siebert, Stefan Kliesch, Ulrike Grittner, Hansjörg Bäzner, Thomas Liebig, Matthias Endres, Jochen B Fiebach, Christian H Nolte, Martin Ebinger, Hans Henkes
BACKGROUND AND PURPOSE: Fluid-attenuated inversion recovery hyperintense vessels (FHV) are frequently observed on magnetic resonance imaging in acute stroke patients with proximal vessel occlusion. Whether FHV can serve as a surrogate for the collateral status and predict functional outcome of patients is still a matter of debate. METHODS: Acute ischemic stroke patients with M1-middle cerebral artery occlusion who received magnetic resonance imaging before endovascular treatment in 3 hospitals in Germany between January 2007 and June 2016 were eligible...
February 19, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29459390/first-pass-effect-a-new-measure-for-stroke-thrombectomy-devices
#2
Osama O Zaidat, Alicia C Castonguay, Italo Linfante, Rishi Gupta, Coleman O Martin, William E Holloway, Nils Mueller-Kronast, Joey D English, Guilherme Dabus, Tim W Malisch, Franklin A Marden, Hormozd Bozorgchami, Andrew Xavier, Ansaar T Rai, Michael T Froehler, Aamir Badruddin, Thanh N Nguyen, M Asif Taqi, Michael G Abraham, Albert J Yoo, Vallabh Janardhan, Hashem Shaltoni, Roberta Novakovic, Alex Abou-Chebl, Peng R Chen, Gavin W Britz, Chung-Huan J Sun, Vibhav Bansal, Ritesh Kaushal, Ashish Nanda, Raul G Nogueira
BACKGROUND AND PURPOSE: In acute ischemic stroke, fast and complete recanalization of the occluded vessel is associated with improved outcomes. We describe a novel measure for newer generation devices: the first pass effect (FPE). FPE is defined as achieving a complete recanalization with a single thrombectomy device pass. METHODS: The North American Solitaire Acute Stroke Registry database was used to identify a FPE subgroup. Their baseline features and clinical outcomes were compared with non-FPE patients...
February 19, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29455158/american-heart-association-s-life-s-simple-7-at-middle-age-and-prognosis-after-myocardial-infarction-in-later-life
#3
Yejin Mok, Yingying Sang, Shoshana H Ballew, Casey M Rebholz, Wayne D Rosamond, Gerardo Heiss, Aaron R Folsom, Josef Coresh, Kunihiro Matsushita
BACKGROUND: The American Heart Association recommends focusing on 7 health factors (Life's Simple 7) for primordial prevention of cardiovascular health. However, whether greater adherence to Life's Simple 7 in midlife improves prognosis after myocardial infarction (MI) in later life is unknown. METHODS AND RESULTS: In 1277 participants who developed MI during the ARIC (Atherosclerosis Risk in Communities) Study follow-up, a 14-point score of Life's Simple 7 was constructed according to the status (2 points for ideal, 1 point for intermediate, and 0 points for poor) of each of 7 factors (smoking, adiposity, physical activity, diet, total cholesterol, blood pressure, and fasting glucose) at baseline (1987-1989)...
February 17, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29444987/cardiovascular-risk-prediction-functions-underestimate-risk-in-hiv-infection
#4
Virginia A Triant, Jeremiah Perez, Susan Regan, Joseph M Massaro, James B Meigs, Steven K Grinspoon, Ralph B D'Agostino
Background -Cardiovascular disease (CVD) risk is elevated in HIV-infected individuals, with contributions from both traditional and non-traditional risk factors. The accuracy of established CVD risk prediction functions in HIV is uncertain. We sought to assess the performance of three established CVD risk prediction functions in a longitudinal cohort of HIV-infected men. Methods -Framingham Heart Study (Framingham) functions for hard coronary heart disease (Framingham CHD) and atherosclerotic CVD (Framingham ASCVD) and the American College of Cardiology/American Heart Association (ACC/AHA ASCVD) function were applied to the Partners HIV cohort...
February 14, 2018: Circulation
https://www.readbyqxmd.com/read/29437116/cardiovascular-disease-and-breast-cancer-where-these-entities-intersect-a-scientific-statement-from-the-american-heart-association
#5
REVIEW
Laxmi S Mehta, Karol E Watson, Ana Barac, Theresa M Beckie, Vera Bittner, Salvador Cruz-Flores, Susan Dent, Lavanya Kondapalli, Bonnie Ky, Tochukwu Okwuosa, Ileana L Piña, Annabelle Santos Volgman
Cardiovascular disease (CVD) remains the leading cause of mortality in women, yet many people perceive breast cancer to be the number one threat to women's health. CVD and breast cancer have several overlapping risk factors, such as obesity and smoking. Additionally, current breast cancer treatments can have a negative impact on cardiovascular health (eg, left ventricular dysfunction, accelerated CVD), and for women with pre-existing CVD, this might influence cancer treatment decisions by both the patient and the provider...
February 1, 2018: Circulation
https://www.readbyqxmd.com/read/29427767/an-assessment-of-the-relationship-of-physical-activity-obesity-and-chronic-diseases-conditions-between-active-obese-and-sedentary-normal-weight-american-women-in-a-national-sample
#6
J R Pharr, C A Coughenour, T J Bungum
OBJECTIVE: Obesity and physical inactivity are associated with increased rates of chronic diseases and conditions. However, the 'fit but fat' theory posits that cardiopulmonary fitness (or physical activity) can mitigate risks to health associated with obesity. The purpose of this study was to compare chronic diseases and conditions of highly active/obese women with inactive/normal weight women. STUDY DESIGN: This was a cross-sectional study of the 2015 Behavioral Risk Factor Surveillance System data...
February 7, 2018: Public Health
https://www.readbyqxmd.com/read/29427203/cardiovascular-disease-incidence-in-adolescent-and-young-adult-cancer-survivors-a-retrospective-cohort-study
#7
Theresa H M Keegan, Lawrence H Kushi, Qian Li, Ann Brunson, X Chawla, Helen K Chew, Marcio Malogolowkin, Ted Wun
PURPOSE: Few population-based studies have focused on cardiovascular disease (CVD) risk in adolescent and young adult (AYA; 15-39 years) cancer survivors and none have considered whether CVD risk differs by sociodemographic factors. METHODS: Analyses focused on 79,176 AYA patients diagnosed with 14 first primary cancers in 1996-2012 and surviving > 2 years after diagnosis with follow-up through 2014. Data were obtained from the California Cancer Registry and State hospital discharge data...
February 9, 2018: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29416330/nanomedical-studies-of-the-restoration-of-nitric-oxide-peroxynitrite-balance-in-dysfunctional-endothelium-by-1-25-dihydroxy-vitamin-d3-clinical-implications-for-cardiovascular-diseases
#8
Alamzeb Khan, Hazem Dawoud, Tadeusz Malinski
Background: Clinical studies indicate that vitamin D3 improves circulation and may have beneficial effects in hypertension. This study uses nanomedical systems to investigate the role of 1,25-dihydroxy vitamin D3 in the preservation/restoration of endothelial function in an angiotensin II (Ang II) cellular model of hypertension. Methods: 1,25-dihydroxy vitamin D3-stimulated nitric oxide (NO) and peroxynitrite (ONOO-) concentrations were measured in situ with nanosensors (200-300 mm diameter with a detection limit of 1 nM) in human umbilical vein endothelial cells of African American (AA) and Caucasian American (CA) donors exposed to Ang II...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29409152/is-rheumatoid-arthritis-a-cardiovascular-risk-equivalent-to-diabetes
#9
Jeffrey R Curtis, Shuo Yang, Jasvinder A Singh, Fenglong Xie, Lang Chen, Huifeng Yun, Paul Muntner, Shia T Kent, Emily B Levitan, Monika M Safford, Kenneth G Saag, Jie Zhang
BACKGROUND/PURPOSE: The 2013 American College of Cardiology/American Heart Association (ACC/AHA) cholesterol treatment guidelines recommend statins for patients with diabetes aged 40-75 years due to their elevated cardiovascular disease (CVD) risk. We compared the incidence of hospitalized acute myocardial infarction (MI), stroke, and coronary revascularization according to whether patients had diabetes, rheumatoid arthritis (RA), both or neither. METHODS: Using 2006 to 2010 private and public health plan claims, we identified 4 mutually exclusive retrospective cohorts age>40: patients with 1) RA and diabetes; 2) RA only; 3) diabetes only; 4) neither condition...
February 6, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29395765/emergency-medicine-considerations-in-atrial-fibrillation
#10
REVIEW
Brit Long, Jennifer Robertson, Alex Koyfman, Kurian Maliel, Justin R Warix
BACKGROUND: Atrial fibrillation (AF) is an abnormal heart rhythm which may lead to stroke, heart failure, and death. Emergency physicians play a role in diagnosing AF, managing symptoms, and lessening complications from this dysrhythmia. OBJECTIVE: This review evaluates recent literature and addresses ED considerations in the management of AF. DISCUSSION: Emergency physicians should first assess patient clinical stability and evaluate and treat reversible causes...
January 30, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29395420/patient-characteristics-and-in-hospital-outcomes-of-emergency-carotid-endarterectomy-and-carotid-stenting-after-stroke-in-evolution
#11
Christoph Knappich, Andreas Kuehnl, Pavlos Tsantilas, Sofie Schmid, Thorben Breitkreuz, Michael Kallmayer, Alexander Zimmermann, Hans-Henning Eckstein
OBJECTIVE: The objective of this study was to describe characteristics and in-hospital outcomes of patients treated with carotid endarterectomy (CEA) and carotid artery stenting (CAS) for stroke in evolution (SIE) under routine conditions in Germany. METHODS: This secondary data analysis is based on the German statutory quality assurance database for carotid revascularization procedures. Patients with SIE who had undergone CEA or CAS were included. The primary outcome was any new stroke or all-cause death until hospital discharge...
January 27, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29392680/power-of-peer-support-to-change-health-behavior-to-reduce-risks-for-heart-disease-and-stroke-for-african-american-men-in-a-faith-based-community
#12
Sohye Lee, Erica Schorr, Niloufar Niakosari Hadidi, Robin Kelley, Diane Treat-Jacobson, Ruth Lindquist
INTRODUCTION: Peer support has powerful potential to improve outcomes in a program of health behavior change; yet, how peer support is perceived by participants, its role, and how it contributes to intervention efficacy is not known, especially among African Americans. The purpose of this study was to identify the subjectively perceived experience and potential contributions of peer support to the outcomes of a peer group behavioral intervention designed to change health behavior to reduce risks for heart disease and stroke in African American men in a faith-based community...
February 1, 2018: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29386200/heart-disease-and-stroke-statistics-2018-update-a-report-from-the-american-heart-association
#13
REVIEW
Emelia J Benjamin, Salim S Virani, Clifton W Callaway, Alexander R Chang, Susan Cheng, Stephanie E Chiuve, Mary Cushman, Francesca N Delling, Rajat Deo, Sarah D de Ferranti, Jane F Ferguson, Myriam Fornage, Cathleen Gillespie, Carmen R Isasi, Monik C Jiménez, Lori Chaffin Jordan, Suzanne E Judd, Daniel Lackland, Judith H Lichtman, Lynda Lisabeth, Simin Liu, Chris T Longenecker, Pamela L Lutsey, David B Matchar, Kunihiro Matsushita, Michael E Mussolino, Khurram Nasir, Martin O'Flaherty, Latha P Palaniappan, Dilip K Pandey, Mathew J Reeves, Matthew D Ritchey, Carlos J Rodriguez, Gregory A Roth, Wayne D Rosamond, Uchechukwu K A Sampson, Gary M Satou, Svati H Shah, Nicole L Spartano, David L Tirschwell, Connie W Tsao, Jenifer H Voeks, Joshua Z Willey, John T Wilkins, Jason Hy Wu, Heather M Alger, Sally S Wong, Paul Muntner
No abstract text is available yet for this article.
January 31, 2018: Circulation
https://www.readbyqxmd.com/read/29375010/aggressive-systolic-blood-pressure-control-in-older-subjects-benefits-and-risks
#14
Steven G Chrysant
Systolic hypertension, especially isolated systolic hypertension (ISH) is very common in older subjects aged ≥ 65 years and is a major risk factor for cardiovascular disease (CVD), strokes, heart failure (HF) and chronic kidney disease (CKD). It is also, directly and linearly related with these complications irrespective of sex, or ethnicity, but it is worse with the advancement of age. Effective control of systolic blood pressure (SBP), is associated with significant reduction in the incidence of these complications...
February 1, 2018: Postgraduate Medicine
https://www.readbyqxmd.com/read/29374642/hemiparesis-in-spontaneous-spinal-epidural-haematoma-a-potential-stroke-imitator
#15
Ravish Patel, Aravind Kumar, Kazuya Nishizawa, Naresh Kumar
Spontaneous spinal epidural haematoma (SSEH) is a rare condition that requires urgent surgical intervention in order to prevent permanent neurological deficit. SSEH commonly presents as a paraparesis or tetraparesis. SSEH presenting as a hemiparesis is less common and in such situations, it can be mistaken for a cerebrovascular accident (CVA). Thrombolytic or anticoagulant treatment for CVA can potentially worsen the neurological deficit. We report one such case of SSEH misdiagnosed as a CVA. Treatment with tissue plasminogen activator led to worsening of his condition...
January 26, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29373602/apixaban-5-and-2-5-mg-twice-daily-versus-warfarin-for-stroke-prevention-in-nonvalvular-atrial-fibrillation-patients-comparative-effectiveness-and-safety-evaluated-using-a-propensity-score-matched-approach
#16
Xiaoyan Li, Allison Keshishian, Melissa Hamilton, Ruslan Horblyuk, Kiran Gupta, Xuemei Luo, Jack Mardekian, Keith Friend, Anagha Nadkarni, Xianying Pan, Gregory Y H Lip, Steve Deitelzweig
Prior real-world studies have shown that apixaban is associated with a reduced risk of stroke/systemic embolism (stroke/SE) and major bleeding versus warfarin. However, few studies evaluated the effectiveness and safety of apixaban according to its dosage, and most studies contained limited numbers of patients prescribed 2.5 mg twice-daily (BID) apixaban. Using pooled data from 4 American claims database sources, baseline characteristics and outcomes for patients prescribed 5 mg BID and 2.5 mg BID apixaban versus warfarin were compared...
2018: PloS One
https://www.readbyqxmd.com/read/29373032/tissue-level-diet-and-sex-by-diet-interactions-reveal-unique-metabolite-and-clustering-profiles-using-untargeted-liquid-chromatography-mass-spectrometry-on-adipose-skeletal-muscle-and-liver-tissue-in-c57bl6-j-mice
#17
Ann Wells, William T Barrington, Stephen Dearth, Amanda May, David W Threadgill, Shawn R Campagna, Brynn H Voy
Dietary intervention is commonly used for weight loss or to improve health, as diet-induced obesity increases risk of developing type 2 diabetes, hypertension, cardiovascular disease, stroke, osteoarthritis, and certain cancers. Various dietary patterns are associated with effects on health, yet little is known about the effects of diet at the tissue level. Using untargeted metabolomics, this study aimed to identify changes in water-soluble metabolites in C57BL/6J males and females, fed one of five diets (Japanese, ketogenic, Mediterranean, American, and standard mouse chow) for seven months...
January 26, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29371220/ethnic-differences-in-prevalence-of-post-stroke-depression
#18
Liming Dong, Brisa N Sánchez, Lesli E Skolarus, Lewis B Morgenstern, Lynda D Lisabeth
BACKGROUND: Little is known about ethnic differences in poststroke depression (PSD) in the United States. This study aims to estimate the prevalence of PSD at 90 days after first-ever stroke and to examine ethnic differences in the prevalence between Mexican Americans (MAs) and non-Hispanic whites (NHWs). METHODS AND RESULTS: Stroke cases from 2011 to 2015 were identified from the BASIC project (Brain Attack Surveillance in Corpus Christi)-a population-based stroke surveillance study in south Texas...
February 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29370183/oral-anticoagulant-re-initiation-following-intracerebral-hemorrhage-in-non-valvular-atrial-fibrillation-global-survey-of-the-practices-of-neurologists-neurosurgeons-and-thrombosis-experts
#19
Yan Xu, Ashkan Shoamanesh, Sam Schulman, Dar Dowlatshahi, Rustam Al-Shahi Salman, Ioana Doina Moldovan, Philip Stephen Wells, Fahad AlKherayf
BACKGROUND: While oral anticoagulants (OACs) are highly effective for ischemic stroke prevention in atrial fibrillation, intracerebral hemorrhage (ICH) remains the most feared complication of OAC. Clinical controversy remains regarding OAC resumption and its timing for ICH survivors with atrial fibrillation because the balance between risks and benefits has not been investigated in randomized trials. AIMS/HYPOTHESIS: To survey the practice of stroke neurologists, thrombosis experts and neurosurgeons on OAC re-initiation following OAC-associated ICH...
2018: PloS One
https://www.readbyqxmd.com/read/29367334/2018-guidelines-for-the-early-management-of-patients-with-acute-ischemic-stroke-a-guideline-for-healthcare-professionals-from-the-american-heart-association-american-stroke-association
#20
REVIEW
William J Powers, Alejandro A Rabinstein, Teri Ackerson, Opeolu M Adeoye, Nicholas C Bambakidis, Kyra Becker, José Biller, Michael Brown, Bart M Demaerschalk, Brian Hoh, Edward C Jauch, Chelsea S Kidwell, Thabele M Leslie-Mazwi, Bruce Ovbiagele, Phillip A Scott, Kevin N Sheth, Andrew M Southerland, Deborah V Summers, David L Tirschwell
BACKGROUND AND PURPOSE: The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations for clinicians caring for adult patients with acute arterial ischemic stroke in a single document. The intended audiences are prehospital care providers, physicians, allied health professionals, and hospital administrators. These guidelines supersede the 2013 guidelines and subsequent updates. METHODS: Members of the writing group were appointed by the American Heart Association Stroke Council's Scientific Statements Oversight Committee, representing various areas of medical expertise...
January 24, 2018: Stroke; a Journal of Cerebral Circulation
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