keyword
https://read.qxmd.com/read/38502734/cardiac-magnetic-resonance-to-predict-cardiac-mass-malignancy-the-cmr-mass-score
#21
JOURNAL ARTICLE
Pasquale Paolisso, Luca Bergamaschi, Francesco Angeli, Marta Belmonte, Alberto Foà, Lisa Canton, Damiano Fedele, Matteo Armillotta, Angelo Sansonetti, Francesca Bodega, Sara Amicone, Nicole Suma, Emanuele Gallinoro, Domenico Attinà, Fabio Niro, Paola Rucci, Elisa Gherbesi, Stefano Carugo, Saima Musthaq, Andrea Baggiano, Anna Giulia Pavon, Marco Guglielmo, Edoardo Conte, Daniele Andreini, Gianluca Pontone, Luigi Lovato, Carmine Pizzi
BACKGROUND: Multimodality imaging is currently suggested for the noninvasive diagnosis of cardiac masses. The identification of cardiac masses' malignant nature is essential to guide proper treatment. We aimed to develop a cardiac magnetic resonance (CMR)-derived model including mass localization, morphology, and tissue characterization to predict malignancy (with histology as gold standard), to compare its accuracy versus the diagnostic echocardiographic mass score, and to evaluate its prognostic ability...
March 2024: Circulation. Cardiovascular Imaging
https://read.qxmd.com/read/38497197/a-nomogram-to-predict-lung-cancer-in-pulmonary-lesions-for-tuberculosis-infection-patients
#22
JOURNAL ARTICLE
Zhi Xia, Xueyao Rong, Qiong Chen, Min Fang, Jian Xiao
Similar clinical features make the differential diagnosis difficult, particularly between lung cancer and pulmonary tuberculosis (TB), without pathological evidence for patients with concomitant TB infection. Our study aimed to build a nomogram to predict malignant pulmonary lesions applicable to clinical practice. We retrospectively analyzed clinical characteristics, imaging features, and laboratory indicators of TB infection patients diagnosed with lung cancer or active pulmonary TB at Xiangya Hospital of Central South University...
March 13, 2024: Monaldi Archives for Chest Disease
https://read.qxmd.com/read/38496208/isolated-malignant-pleural-effusion-in-a-child-unusual-presentation-of-acute-leukemia
#23
Srinija Garlapati, Sampada Tambolkar, Sarita Verma, Nakul V Pathak, Manojkumar G Patil
Pleural effusion in the pediatric population is an abnormal pathology characterized by the accumulation of fluids between the parietal and visceral pleura. The etiology of this excessive fluid accumulation can be attributed to both infectious and non-infectious factors. Notably, Streptococcus pneumoniae stands out as the predominant infectious agent responsible for this condition. Non-infectious causative factors encompass hematolymphoid malignancies, congestive heart failure, hemothorax, hypoalbuminemia, and iatrogenic causes...
February 2024: Curēus
https://read.qxmd.com/read/38486345/drug-induced-chylothorax-as-a-rare-pleural-complication-in-dasatinib-therapy-for-chronic-myeloid-leukaemia
#24
JOURNAL ARTICLE
Isaac Ks Ng, Mamta Ruparel, Esther Hl Chan, Kay Leong Khoo
Chylothorax is a lymphatic chylous pleural effusion typically associated with traumatic (iatrogenic, non-iatrogenic) and non-traumatic (infections, malignancy, lymphatic disorders) aetiologies. Drug-induced chylothorax is uncommon and mostly reported in association with BCR-ABL tyrosine kinase inhibitor therapy.
March 14, 2024: Journal of the Royal College of Physicians of Edinburgh
https://read.qxmd.com/read/38482464/high-throughput-and-simultaneous-inertial-separation-of-tumor-cells-and-clusters-from-malignant-effusions-using-spiral-contraction-expansion-channels
#25
JOURNAL ARTICLE
Zhixian Zhu, Hui Ren, Dan Wu, Zhonghua Ni, Nan Xiang
Tumor cell clusters are regarded as critical factors in cancer pathophysiology, and increasing evidence of their higher treatment resistance and metastasis compared to single tumor cells has been obtained. However, existing cell separation methods that are designed for single tumor cells cannot be used to simultaneously purify tumor cell clusters. To address this problem, we demonstrated a microfluidic approach for the high-throughput, continuous-flow ternary separation of single tumor cells, tumor cell clusters, and WBCs from clinical pleural or abdominal effusions by coupling slanted spiral channels and periodic contraction-expansion arrays...
2024: Microsystems & Nanoengineering
https://read.qxmd.com/read/38481129/purulent-pericarditis-caused-by-methicillin-sensitive-staphylococcus-aureus-bacteriuria
#26
JOURNAL ARTICLE
Lorraine Mascarenhas, Dzhalal Agakishiev, Morgan Freeman, Scott Hubers
BACKGROUND: Purulent pericarditis (PP)- a purulent infection involving the pericardial space-requires a high index of suspicion for diagnosis as it often lacks characteristic signs of pericarditis and carries a mortality rate as high as 40% even with treatment. Common risk factors include immunosuppression, diabetes mellitus, thoracic surgery, malignancy, and uremia. Most reported cases of PP occur in individuals with predisposing risk factors, such as immunosuppression, and result from more commonly observed preceding infections, such as pneumonia, osteomyelitis, and meningitis...
March 13, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38475858/immune-modulation-in-malignant-pleural-effusion-from-microenvironment-to-therapeutic-implications
#27
REVIEW
Shan Ge, Yuwei Zhao, Jun Liang, Zhongning He, Kai Li, Guanghui Zhang, Baojin Hua, Honggang Zheng, Qiujun Guo, Runzhi Qi, Zhan Shi
Immune microenvironment and immunotherapy have become the focus and frontier of tumor research, and the immune checkpoint inhibitors has provided novel strategies for tumor treatment. Malignant pleural effusion (MPE) is a common end-stage manifestation of lung cancer, malignant pleural mesothelioma and other thoracic malignancies, which is invasive and often accompanied by poor prognosis, affecting the quality of life of affected patients. Currently, clinical therapy for MPE is limited to pleural puncture, pleural fixation, catheter drainage, and other palliative therapies...
March 12, 2024: Cancer Cell International
https://read.qxmd.com/read/38475834/pleural-epithelioid-hemangioendothelioma-in-a-39-year-old-female-a-case-report
#28
JOURNAL ARTICLE
Parviz Mardani, Reza Shahriarirad, Mohammad Nekooeian, Mohammad Hossein Anbardar, Bizhan Ziaian, Hooman Kamran, Nazanin Ayare, Masoud Vafabin, Damoun Fouladi
BACKGROUND: Epithelioid hemangioendothelioma (EHE) is a rare malignancy of vascular origin which can be primarily be seen in various tissues. EHE originating from the pleura is an even more uncommon subtype which may mimic mesothelioma and pleural carcinomatosis. The prognosis of pleural EHE is poor and there is no consensus on the optimal therapeutic approach. CASE PRESENTATION: A 39-year-old middle-eastern female presented with progressive dyspnea and left shoulder discomfort...
March 12, 2024: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/38469399/diagnostic-analysis-of-pleural-fluid-cell-blocks-using-relevant-immunohistochemical-markers-in-clinically-suspicious-cases-of-malignancy
#29
JOURNAL ARTICLE
Jules Kurian Mathew, Gopalan Nair Rajan, Abhilash Kudilipparambil Kunju
OBJECTIVE: Thoracocentesis is a less invasive and expensive procedure than pleural biopsy, enabling sample collection for cytological evaluation. Cell blocks prepared from these samples provide histopathological diagnoses; further, immunohistochemistry (IHC) can be performed for subtyping malignancies, guiding the clinician in choosing the appropriate treatment modality for the patient. We aimed to determine the various histological subtypes of malignancies using cell block IHC and compare the cell block and conventional cytology methods for diagnosing malignant pleural effusion...
2024: CytoJournal
https://read.qxmd.com/read/38469240/unveiling-the-mystery-a-rare-case-of-localized-malignant-pericardial-mesothelioma-case-report
#30
Yan Zhang, Mingjie Pang
Primary malignant pericardial mesothelioma (PMPM) is a rare pericardial malignant tumor. Most manifestations of PMPM are localized or diffuse masses surrounding the heart. The prognosis of diffuse PMPM is poor due to the difficulty of surgical resection. Although the edge of localized PMPM is clear and can be easily resected, the diagnosis of this disease is difficult. Timely diagnosis and proper treatment are key to a good prognosis. Here, we report a patient with localized PMPM and describe the method for the diagnosis of this disease...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38465648/cardiovascular-management-of-patients-undergoing-hematopoietic-stem-cell-transplantation-from-pretransplantation-to-survivorship-a-scientific-statement-from-the-american-heart-association
#31
REVIEW
Salim S Hayek, Vlad G Zaha, Carmel Bogle, Anita Deswal, Amelia Langston, Seth Rotz, Alexi Vasbinder, Eric Yang, Tochukwu Okwuosa
Hematopoietic stem cell transplantation can cure various disorders but poses cardiovascular risks, especially for elderly patients and those with cardiovascular diseases. Cardiovascular evaluations are crucial in pretransplantation assessments, but guidelines are lacking. This American Heart Association scientific statement summarizes the data on transplantation-related complications and provides guidance for the cardiovascular management throughout transplantation. Hematopoietic stem cell transplantation consists of 4 phases: pretransplantation workup, conditioning therapy and infusion, immediate posttransplantation period, and long-term survivorship...
March 11, 2024: Circulation
https://read.qxmd.com/read/38463870/development-of-machine-learning-based-malignant-pericardial-effusion-related-model-in-breast-cancer-implications-for-clinical-significance-tumor-immune-and-drug-therapy
#32
JOURNAL ARTICLE
Wendi Zhan, Haihong Hu, Bo Hao, Hongxia Zhu, Ting Yan, Jingdi Zhang, Siyu Wang, Saiyang Liu, Taolan Zhang
BACKGROUND: Malignant pericardial effusion (MPE) is a common complication of advanced breast cancer (BRCA) and plays an important role in BRCA. This study is aims to construct a prognostic model based on MPE-related genes for predicting the prognosis of breast cancer. METHODS: The BRCA samples are analyzed based on the expression of MPE-related genes by using an unsupervised cluster analysis method. This study processes the data by least absolute shrinkage and selection operator and multivariate Cox analysis, and uses machine learning algorithms to construct BRCA prognostic model and develop web tool...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38463096/medical-thoracoscopy-with-cryobiopsy-as-diagnostic-tool-for-pleural-metastatic-in-cutaneous-squamous-cell-carcinoma-a-rare-case-report
#33
Jimmy Tanamas, Melissa Angela Chionardes, Thomas Handoyo, Fathur Nur Kholis, Farida, Banteng Hanang Wibisono, Agus Suryanto, Eric Daniel Tenda, Gurmeet Singh, Eko Adhi Pangarsa, Bambang Satoto, Faiza Rizky Septarina, Dik Puspasari
INTRODUCTION: Distance metastasis of cutaneous squamous cell carcinoma (cSCC) to pleural is rarely reported, and meets difficulties in diagnosing due to quality of pleural biopsy sample. This case presented a novel technique by using cryobiopsy to obtain adequate sample and was first conducted in our hospital. CASE PRESENTATION: A 62-years-old man admitted to hospital with dyspnoea due to massive right pleural effusion. Lung multi-sliced computed tomography showed right lung pleural effusion with compression atelectasis as well as collapse of medial lobe and upper lobe, multiple solitary nodules on mediastinal, costal antero-posterior and right diaphragm pleural part...
March 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38455606/double-fatal-consequences-of-distance-metastasis-in-nasopharyngeal-carcinoma-after-a-completed-chemoradiation-in-pregnancy-a-case-report
#34
JOURNAL ARTICLE
Niken A Utami, Liza Muknisa
Distant metastasis in nasopharyngeal carcinoma (NPC) patients is one of the reasons for the decreased life expectancy with the most common metastasis spreads are to the bone, liver, and lung. Hepatoma is the most frequent liver malignancy and is one of the highest causes of cancer death worldwide and this can be as a result of NPC metastasis. The aim of this case report was to present a patient with hepatoma in pregnancy as a result of NPC metastasis. A 34-year-old pregnant female at 24-25 weeks of gestation presented with a chief complaint of heartburn and unbearable pain radiating to the back...
December 2023: Narra J
https://read.qxmd.com/read/38452642/a-primary-pleural-hydatid-cyst-was-discovered-months-after-an-undiagnosed-pneumothorax-a-diagnostic-and-therapeutic-dilemma-in-a-rare-case-report-from-syria
#35
Hamdah Hanifa, Turki Al-Shaher, Mamoun Jaber, Jaafar Alatm, Khayry Al-Shami, Salem Algomaa Alhadid
INTRODUCTION: Primary pleural hydatid cysts (PPHCs) are a rare clinical condition caused by the larval stage of the parasite Echinococcus granulosus. They occur in <1 % of all hydatid cysts in the body and can cause serious complications such as pneumothorax, pleural effusion, and mediastinal shift. PRESENTATION OF CASE: We report a rare case of a 28-year-old female who was initially misdiagnosed and ignored her pneumothorax for several months, resulting in progressive dyspnea and chest pain...
March 5, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38451563/scores-for-diagnosing-the-malignant-etiology-of-pericardial-effusion-a-valuable-initial-aid-in-the-investigation
#36
EDITORIAL
Wolney de Andrade Martins
No abstract text is available yet for this article.
2024: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/38449961/anaplastic-carcinoma-arising-from-a-mural-nodule-in-benign-mucinous-cystadenoma
#37
Natalia M Barron-Cervantes, Alejandro Martinez-Esteban, Fabiola M Nuccio-Giordano, Regina Faes-Petersen, Alejandro D G Gidi, Eduardo Villegas-Tovar
Giant abdominopelvic tumors continue to present a diagnostic and therapeutic challenge for all surgeons despite all the advances in the world of imaging. Particularly, one of the most important challenges is to determine its probable origin for adequate surgical planning. Even though mostly all of these tumors are benign ovarian tumors, extraordinarily, malignant mural nodules may develop from the wall of these benign tumors, carrying an invariable unfavorable prognosis for the patient. This case highlights the importance of a correct diagnostic approach using ultrasound and abdominal computed tomography scans and confirming the diagnosis through a histopathologic examination...
February 2024: Curēus
https://read.qxmd.com/read/38441189/cytomorphology-of-metastatic-malignant-peripheral-nerve-sheath-tumour-present-in-pleural-fluid-case-study-and-literature-review
#38
Yun-Cui Pan, Yi Xu, Qian Wang, Zhi-Hong Xian, Shu-Hui Zhang
The cytomorphology of MPNST in effusion specimens is rarely described. In this paper, the detailed cytopathological and immunohistochemical characteristics of metastatic MPNST has been described in pleural effusion. Patients' medical history and the judicious utilization of ancillary studies contribute to ensure precise cytological diagnoses. The cytomorphology of malignant peripheral nerve sheath tumour (MPNST) in effusion specimens can be diagnostically challenging. The author presents detailed cytopathological and immunohistochemical characteristics of a case of metastatic MPNST in pleural effusion...
March 5, 2024: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://read.qxmd.com/read/38440043/cardiac-tamponade-and-primary-biliary-cholangitis-an-unusual-presentation-and-a-rare-association-of-systemic-lupus-erythematosus
#39
Ana Carvoeiro, Rita Mota, Patrícia Sobrosa, Alexandra Esteves
Systemic lupus erythematosus (SLE) is a disease known for its multiple manifestations, including numerous cardiac complications. While pericardial effusions are common in patients with SLE, cardiac tamponade is rare, and it is even rarer as an initial and isolated clinical manifestation of SLE. We describe a case of a young adult woman who presented with a four-week history of shortness of breath, orthopnea, and paroxysmal nocturnal dyspnea. Chest radiography revealed a significant increase in the cardiothoracic index, and transthoracic echocardiography confirmed a life-threatening cardiac tamponade that necessitated emergency pericardiocentesis and high-dose corticosteroids...
February 2024: Curēus
https://read.qxmd.com/read/38435931/desmoplastic-small-round-cell-tumors-presented-with-st-segment-elevation-myocardial-infarction-and-cardiac-tamponade-in-a-young-adult-female-a-case-report
#40
Kensuke Takaoka, Ashwin Venkataraman, Clarke Morihara, Arvin Tan, Witina Techasatian
Desmoplastic small round cell tumors (DSRCT) are very rare and aggressive diseases typically present with abdominal or retroperitoneal masses. We present a case of a young female who presented with ST-segment elevation myocardial infarction and cardiac tamponade and who was found to have DSRCT. The patient was coded at the emergency department. Left heart catheterization showed normal coronary arteries, and pericardiocentesis removed 1,260 mL of bloody pericardial effusions. The patient was stabilized, and a positron emission tomography scan revealed left intrahilar, hilar, and cardiophrenic masses with associated hypermetabolic right hilar, left hilar, subcarinal, costophrenic, aortopulmonary, paratracheal, and mediastinal lymphadenopathy...
January 2024: Curēus
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