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Malignant effusion

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https://www.readbyqxmd.com/read/29682436/metastatic-sternal-osteosarcoma-a-rare-tumor
#1
Muhammad Masab, Ena Arora, Sorab Gupta, Hafsa Farooq, Vishal Jindal, Shorabh Sharma
Osteosarcoma is the most common primary malignant tumor of the long bones. However, primary osteosarcoma of the chest wall, particularly the sternum, is an extremely rare occurrence. We report a 36-year-old male presenting with a hard, immobile, palpable, anterior chest wall mass. A computed tomographic (CT) scan showed a large destructive anterior mediastinal mass involving the manubrium and sternum with multiple bilateral calcified lung masses, pleural effusions and partially calcified aortopulmonary, right hilar and subcarinal lymphadenopathy...
February 19, 2018: Curēus
https://www.readbyqxmd.com/read/29682355/a-patient-presenting-with-cardiac-tamponade-and-the-challenges-of-finding-its-cause-a-cardiac-angiosarcoma
#2
Roshanak Habibi, Negar Faramarzi, Alvaro J Altamirano, Shahriar Dadkhah
Primary malignancies of the heart are so rare that most of the available data come from case reports or large single-center-based studies, with the overall incidence of 0.02% in the United States. Diagnosis in case of an isolated pericardial effusion as presentation is challenging, and determining that an angiosarcoma is even more challenging. Here, we presented a rare case of pericardial angiosarcoma which presented to us with tamponade. The patient eventually was diagnosed through pericardiectomy. A multimodality approach was attempted to treat the cancer...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29681837/unusual-case-of-vogt-koyanagi-harada-disease-associated-with-sapho-syndrome-a-case-report
#3
Miyuki Hasegawa, Akira Fukutomi, Akiko Jinno, Kyoko Fujita, Motohiro Kamei
A 66-year-old Japanese woman who was diagnosed with synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome presented with bilateral blurred vision 4 months prior to visiting our hospital. She had visited a local ophthalmology clinic first. She was diagnosed with conjunctivitis and was prescribed antibacterial eye drops. The symptoms persisted in spite of treatment. She was then referred to our hospital. At her initial visit, the visual acuities were 0.6 in both eyes. A slit-lamp examination revealed bilateral shallow anterior chamber, and intraocular pressures of 18 mm Hg in the right eye and 16 mm Hg in the left eye...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29673407/hypercalcemia-as-a-rare-presentation-of-angioimmunoblastic-t-cell-lymphoma-a-case-report
#4
Sana Chams, Inaya Hajj Hussein, Skye El Sayegh, Nour Chams, Khalid Zakaria
BACKGROUND: Angioimmunoblastic T cell lymphoma is a rare malignancy, accounting for only 2% of all non-Hodgkin lymphomas, first described in the 1970s and subsequently accepted as a distinct entity in the current World Health Organization classification. Due to the paucity of this disease, there is still no identifiable etiology, no consistent risk factors, and the pathogenesis remains unclear. CASE PRESENTATION: An 83-year-old Caucasian man presented to an emergency department with palpitations and was found to have atrial fibrillation...
April 20, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29673113/evaluation-of-photoshop-based-image-analysis-in-cytologic-diagnosis-of-pleural-fluid-in-comparison-with-conventional-modalities
#5
Amir Hossein Jafarian, Aida Tasbandi, Nema Mohamadian Roshan
BACKGROUND: The aim of this study is to investigate and compare the results of digital image analysis in pleural effusion cytology samples with conventional modalities. MATERIALS AND METHODS: In this cross-sectional study, 53 pleural fluid cytology smears from Qaem hospital pathology department, located in Mashhad, Iran were investigated. Prior to digital analysis, all specimens were evaluated by two pathologists and categorized into three groups as: benign, suspicious, and malignant...
April 19, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29669524/pressurized-intraperitoneal-aerosol-chemotherapy-pipac-for-the-treatment-of-malignant-mesothelioma
#6
Urs Giger-Pabst, Cédric Demtröder, Thomas A Falkenstein, Mehdi Ouaissi, Thorsten O Götze, Günther A Rezniczek, Clemens B Tempfer
BACKGROUND: Patients with recurrent malignant epithelioid mesothelioma (MM) after surgery and standard chemotherapy with cisplatin and pemetrexed have limited treatment options. METHODS: We performed a retrospective cohort study of patients with recurrent MM undergoing Pressurized IntraPeritoneal/Thoracal Aerosol Chemotherapy (PIPAC/PITAC) with doxorubicin 1.5 mg/m2 and cisplatin 7.5 mg/m2 . Data were retrospectively collected in a prospective registry of patients undergoing PIPAC/PITAC...
April 18, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29669178/the-utility-of-multiparametric-flow-cytometry-in-the-detection-of-primary-effusion-lymphoma-pel
#7
Jacobo Galán, Isaac Martin, Itziar Carmona, José María Rodriguez-Barbero, Esperanza Cuadrado, Luis García-Alonso, José Antonio García-Vela
Primary effusion lymphoma (PEL) is a rare B cell lymphoproliferative disorder that arises predominantly in body cavities causing malignant effusions.The incidence of PEL is very low, accounting for approximately 4% of all HIV-associated non-Hodgkin lymphomas. PEL has also been described in elderly patients and after solid-organ transplantation. It is associated in all cases with human herpesvirus 8 (HHV8). We describe a case of PEL in a 88-year-old HIV-negative woman who presented with progressive dyspnea and moderate right-sided pleural effusion without significate lymphadenopathies or other effusions...
April 18, 2018: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/29656754/malignant-cells-from-pleural-fluids-in-malignant-mesothelioma-patients-reveal-novel-mutations
#8
Sophie Sneddon, Ian Dick, Y C Gary Lee, A W Bill Musk, Ann-Marie Patch, John V Pearson, Nicola Waddell, Richard J N Allcock, Robert A Holt, Bruce W S Robinson, Jenette Creaney
OBJECTIVES: Malignant mesothelioma (MM) is an asbestos related tumour affecting cells of serosal cavities. More than 70% of MM patients develop pleural effusions which contain tumour cells, representing a readily accessible source of malignant cells for genetic analysis. Although common somatic mutations and losses have been identified in solid MM tumours, the characterization of tumour cells within pleural effusions could provide novel insights but is little studied. MATERIALS AND METHODS: DNA and RNA were extracted from cells from short term cultures of 27 human MM pleural effusion samples...
May 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29651368/synchronous-pulmonary-neoplasms-a-chance-occurrence-or-is-there-more-than-meets-the-eye
#9
Uroosa Ibrahim, Amina Saqib, Manisha Pant, Gwenalyn Garcia, Marcel Odaimi
Primary bronchus-associated lymphoid tissue (BALT) lymphoma comprises 5% of non-Hodgkin's lymphoma (NHL) and usually has an indolent course. Synchronous primary lung cancers with BALT lymphoma are seldom seen in patients with adenocarcinoma of the lung. Synchronous squamous cell carcinoma (SCC) and BALT lymphoma is an extremely rare occurrence. We report an unusual case of stage 4 BALT lymphoma requiring treatment that revealed an underlying ipsilateral mass causing a diagnostic dilemma. An 84-year-old female with a history of systemic lupus erythematosus, deep vein thrombosis, and thrombotic microangiopathy presented to the hospital with cough and dyspnea on exertion...
February 6, 2018: Curēus
https://www.readbyqxmd.com/read/29649989/evaluation-of-efficacy-and-safety-for-brucea-javanica-oil-emulsion-in-the-control-of-the-malignant-pleural-effusions-via-thoracic-perfusion
#10
Dai Fuhong, Gao Xiang, Li Haiying, Wang Jiangye, Gao Xueming, Chai Wenxiao
BACKGROUND: Brucea javanica oil emulsion (BJOE) is traditional Chinese medicine with implicated anti-tumor activity, which has been used for treating lung cancer in China. The aim of this investigation was to evaluate the effects and safety of intrapleural injection of BJOE in treating malignant pleural effusion (MPE). METHODS: The randomised controlled trials (RCTs) on the effects and safety of BJOE in treating MPE were searched from electronic medical database including MEDLINE, SCI, EMBASE, Cochrance Library and CNKI...
April 12, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29643915/prognostic-significance-of-blood-serum-and-ascites-parameters-in-patients-with-malignant-peritoneal-mesothelioma-or-peritoneal-carcinomatosis
#11
Shan-Shan Su, Guo-Qi Zheng, Wen-Jie Yin, Yu-Fei Liang, Ying-Ying Liu, Hui Song, Ning-Ning Sun, Yu-Xin Yang
To determine effects of the biochemical and cytological properties of blood, serum, and ascites on survival of patients with malignant peritoneal effusion (MPeE), including malignant peritoneal mesothelioma (MPeM) and peritoneal carcinomatosis (PC), we conducted a retrospective study of patients with MPeE and healthy controls. Potential prognostic factors were identified as follows: age, sex, blood neutrophil-to-lymphocyte ratio (NLR), serum parameters, ascites parameters, serum-ascites albumin gradient, and the ascites-serum LDH ratio...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29643653/utility-of-cytospin-and-cell-block-technology-in-evaluation-of-body-fluids-and-urine-samples-a-comparative-study
#12
Irmeen Qamar, Suhailur Rehman, Ghazala Mehdi, Veena Maheshwari, Hena A Ansari, Sunanda Chauhan
Background: Cytologic examination of body fluids commonly involves the use of direct or sediment smears, cytocentrifuge preparations, membrane filter preparations, or cell block sections. Cytospin and cell block techniques are extremely useful in improving cell yield of thin serous effusions and urine samples, and ensure high diagnostic efficacy. Materials and Methods: We studied cytospin preparations and cell block sections prepared from 180 samples of body fluids and urine samples to compare the relative efficiency of cell retrieval, preservation of cell morphology, ease of application of special stains, and diagnostic efficacy...
April 2018: Journal of Cytology
https://www.readbyqxmd.com/read/29629920/pleural-effusions-in-hematologic-malignancies-and-their-management-with-indwelling-pleural-catheters
#13
Erik Vakil, Carlos A Jimenez, Saadia A Faiz
PURPOSE OF REVIEW: Pleural effusions in patients with hematologic malignancy may represent malignant pleural effusion (MPE) or occur secondary to infection, treatment effects, and other common causes. The impact of MPE on prognosis in this cohort remains unclear. Indwelling pleural catheters (IPCs) are routinely placed for palliation of recurrent symptomatic MPEs, but perceived concerns over infection and bleeding may limit their use in patients with hematologic malignancies. However, recent evidence suggests IPCs are both well tolerated and effective in this cohort...
April 6, 2018: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/29629675/the-current-aetiology-of-malignant-pleural-effusion-in-the-western-cape-province-south-africa
#14
C F N Koegelenberg, S M Bennji, E Boer, P T Schubert, J A Shaw, B W Allwood, E M Irusen
BACKGROUND: Malignant pleural effusion (MPE) represents a very common cause of pleural exudates, and is one of the most challenging pleural disorders to manage. This could be attributed to the paucity of high-quality experimental evidence, and inconsistent practice worldwide. South Africa (SA) currently has no data regarding the aetiology of MPE. OBJECTIVES: To identify the most common malignancies causing MPE in a population served by a large tertiary hospital in SA, and specifically the relative contribution of mesothelioma...
March 28, 2018: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29628470/a-rare-case-of-rush-progression-of-purulent-pericarditis-by-escherichia-coli-in-a-patient-with-malignant-lymphoma
#15
Shunpei Horii, Hirotaka Yada, Kei Ito, Ayumu Osaki, Atsushi Sato, Toyokazu Kimura, Risako Yasuda, Takumi Toya, Takayuki Namba, Nobuyuki Masaki, Takeshi Adachi
Purulent pericarditis is a rare disease in the antibiotic era. The common pathogens of purulent pericarditis are gram-positive species such as Staphylococcus aureus. Streptococcus pneumoniae, Salmonella, Haemophilus, fungal pathogens/tuberculosis can also result in purulent pericarditis. We report an old male case of purulent pericarditis by Escherichia coli. He came to our hospital suffering from leg edema for 3 months. Echocardiography revealed the large amount of pericardial effusion, and he was admitted to test the cause of pericardial effusion without high fever, tachycardia, and shock vital signs...
April 6, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29628402/diagnostic-yield-of-semi-rigid-thoracoscopy-in-the-molecular-characterization-of-pulmonary-malignant-pleural-effusions
#16
Maribel Botana-Rial, Cecilia Mouronte-Roibás, Ana González-Piñeiro, Alberto Fernández-Villar
No abstract text is available yet for this article.
April 5, 2018: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/29624885/procedure-related-tumour-seeding-in-lung-cancer-with-malignant-pleural-effusion-radiological-features-and-outcomes
#17
Kamonwon Cattapan, Wiwatana Tanomkiat, Sarayut L Geater, Nantaka Kiranantawat
INTRODUCTION: Pleural procedures are performed to prove the diagnosis of pleural effusion. This study was to assess the incidence and outcome of pleural procedure-related tumour seeding in lung cancer with malignant pleural effusion, and to review the characteristics of the implanted tumours on computed tomography (CT) images. METHODS: From January 2008 to December 2010, 165 patients with the diagnosis of lung cancer with malignant pleural effusion, who underwent at least one pleural procedure and had follow-up CT, were included...
April 6, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29622690/-malignant-pleural-effusion-with-abdominal-gossypiboma
#18
Tao Fan, Wei Wang, Xiaobo Guo, Qing Geng
No abstract text is available yet for this article.
April 5, 2018: Thorax
https://www.readbyqxmd.com/read/29620164/rapid-point-of-care-testing-for-epidermal-growth-factor-receptor-gene-mutations-in-patients-with-lung-cancer-using-cell-free-dna-from-cytology-specimen-supernatants
#19
Shiho Asaka, Akihiko Yoshizawa, Kazusa Saito, Yukihiro Kobayashi, Hiroshi Yamamoto, Tatsuya Negishi, Rie Nakata, Kazuyuki Matsuda, Akemi Yamaguchi, Takayuki Honda
Epidermal growth factor receptor (EGFR) mutations are associated with responses to EGFR tyrosine kinase inhibitors (EGFR-TKIs) in non-small-cell lung cancer (NSCLC). Our previous study revealed a rapid point-of-care system for detecting EGFR mutations. This system analyzes cell pellets from cytology specimens using droplet-polymerase chain reaction (d-PCR), and has a reaction time of 10 min. The present study aimed to validate the performance of the EGFR d-PCR assay using cell-free DNA (cfDNA) from supernatants obtained from cytology specimens...
March 27, 2018: International Journal of Oncology
https://www.readbyqxmd.com/read/29618325/chylopericardium-in-a-child-with-iga-nephropathy-a-case-report
#20
Yu-Lin Kang, Yun Cui, Ying Wu, Shen Hao, Xin-Yu Kuang, Yu-Cai Zhang, Wen-Yan Huang, Guang-Hua Zhu
BACKGROUND: Chylopericardium effusion is characterized by the accumulation of milky effusion in the pericardium. It is often idiopathic but it can be secondary to trauma, chest radiation, tuberculosis and malignancy. If cardiac tamponade ensues, it becomes life-threatening. Herein we describe chylopericardium tamponade in a child with IgA nephropathy. To the best of our knowledge, this is the first reported case of chylopericardium tamponade in IgA nephropathy. CASE PRESENTATION: A 6 years old boy with IgA nephropathy presented with dyspnea, orthopnea, pretibial pitting edema, ascites and fever...
April 5, 2018: BMC Pediatrics
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