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S M Schellong, H Riess, M Spannagl, H Omran, M Schwarzbach, F Langer, W Gogarten, P Bramlage, R M Bauersachs
Approximately 30% of patients receiving oral anticoagulation using vitamin K antagonists (VKA) require surgery within 2 years. In this context, a clinical decision on the need and the mode of a peri-interventional bridging with heparin is needed. While a few years ago, bridging was almost considered a standard of care, recent study results triggered a discussion on which patients will need bridging at all. Revisiting the currently available recommendations and study results the conclusion can be drawn that the indications for bridging with heparin must nowadays be taken more narrowly and considering the individual patient risk of bleeding and thromboembolism...
June 20, 2018: Der Anaesthesist
A M Attallah, D Omran, M S Marie, M A Abdelrazek, A Salama, R El Essawey, L Mobarak, S Maklad, A Omar
BACKGROUND: A single nucleotide polymorphism (SNP) in the interleukin 28B (IL28B) gene may alter the trajectory of hepatitis C virus (HCV) chronic infection. Several studies have sought to determine a link between the IL28B rs12979860 SNP and the development of HCV-related hepatocellular carcinoma (HCC), but with variable results, consensus is awaited. We hypothesised that IL28B rs12979860 SNP is linked to HCC in patients with HCV type 4. METHODS: IL28B genotyping of 300 patients with HCV related fibrosis (n=100), cirrhosis (n=100) and HCC (n=100) was carried out and the results were analyzed to determine the association between the IL28B genotype and clinical outcome...
June 19, 2018: British Journal of Biomedical Science
Ahmed M Maged, Ameer Elsherief, Hany Hassan, Doaa Salaheldin, Khaled A Omran, Maged Almohamady, Sherif Dahab, Radwa Fahmy, Ahmed AbdelHak, Amira Y Shoab, Rehab Lotfy, Yossra S Lasheen, Hala Nabil, Sahar M Y Elbaradie
OBJECTIVE: To assess the relation between maternal, fetal and neonatal outcomes and different forms of hypertensive disorders associating pregnancy in women needed intensive care units (ICU) admission. METHODS: A prospective case control study conducted on 1238 women admitted to hypertensive intensive care unit at three university hospitals. They were classified into four groups. Group I included 472 women with severe preeclampsia (PE), Group II included 243 women with eclampsia (E); Group III included 396 women diagnosed with E associated with HELLP syndrome and Group IV included 127 women diagnosed as HELLP syndrome...
June 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
Abir Bouaoun, Latifa Ben Omrane, Mohamed Mogaadi, Wièm Douira Khomsi, Asma Zidi, Azza Hammou
The purpose of this study was to assess and analyze the radiation doses during head pediatric CT from different CT units within six Tunisian hospitals representing different geographic regions in order to optimize the dose given and minimize the radiology risk to this category of patients and towards the derivation of national diagnostic reference levels. Patient data and exposure parameters were collected for four age groups (<1, 1-5, 5-10 and 10-15 y). Clinical protocols and exposure settings were analyzed...
April 18, 2018: Radiation Protection Dosimetry
Abdelfattah M Attallah, Dalia Omran, Mohamed M Omran, Mohamed A Abdelrazek, Rania Zayed, Riham El Essawey, Sameh Saif, Azza Farid, Mohamed Hassany, Ayman Yosry, Ashraf Omar
INTRODUCTION AND AIM: The correlation between interleukin-28B (IL-28B) polymorphisms and chronic hepatitis C (CHC) progression is debatable. Here, we aimed to evaluate the relation between IL-28B C/T genotypes and the development of cirrhotic liver. Extracellular matrix (ECM) proteins, FibroScan and model for end-stage liver disease (MELD) were used to substantiate the severity of liver disease. MATERIAL AND METHODS: IL-28B rs12979860, liver stiffness and ECM proteins were assessed in 272 CHC patients...
July 2018: Annals of Hepatology
Sonia Mejri, Yassine Mabrouk, Omrane Belhadj, Mouldi Saidi
PURPOSE: Broomrape produces serious damage to many legume crops and particularly becomes a limiting factor for faba bean (Vicia faba L.) production in the Mediterranean basin. Currently, several traditional methods of control have been developed, but none has proved to be effective for this parasite. However, breeding for resistance to this pest remains as one of the most feasible and environmentally friendly methods for managing broomrape, but the mechanisms governing the interaction between the parasite and the host are not yet well understood...
June 12, 2018: International Journal of Radiation Biology
Saeid Mahdavi Omran, Maryam Rezaei Dastjerdi, Maryam Zuashkiani, Vahid Moqarabzadeh, Mojtaba Taghizadeh-Armaki
Background: Candida -associated denture stomatitis (CADS) is a common fungal infection in people who wear dentures. The main objective of this study was to make molecular identification of causative agents of CADS and in vitro antifungal susceptibility testing (AFST) in the Iranian patients with denture stomatitis. Methods: A total of 134 Candida spp. were obtained from patients with denture stomatitis. The Candida spp. were identified using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) involving the universal internal transcribed spacer (ITS1 and ITS4) primers, which were subjected to digestion with MspI and BlnI restriction enzymes...
2018: BioMed Research International
Rania S Nageeb, Alaa A Omran, Ghada S Nageeb, Manal A Yousef, Yassir A A Mohammad, Amal Fawzy
Background: Multiple sclerosis (MS) and systemic lupus erythematosus (SLE) are chronic autoimmune mediated diseases with strong genetic and environmental components. The aim of this study is to evaluate the association of STAT4 gene polymorphism with multiple sclerosis (MS) and juvenile onset systemic lupus erythematosus (JO-SLE) and its relation to disease severity. Methods: Group 1 consisted of 40 MS patients while group 2 included 40 JO-SLE patients. Forty healthy volunteers (controls) were included in this study...
2018: The Egyptian journal of neurology, psychiatry and neurosurgery
Layla Salih Al-Omran, Stuart Harrad
To test the hypothesis that assessments of human exposure to PBDEs and NBFRs (PBEB, EH-TBB, BEH-TEBP, BTBPE and DBDPE) via dust ingestion should take into account spatial and temporal variability in dust contamination; 238 dust samples were collected from nine different rooms within three homes in Birmingham UK. In each room, three different dust samples were taken at monthly intervals for nine months, one sample from elevated surfaces and two samples from two different floor areas. Substantial within-room and within-home spatial variability in BFR concentrations was apparent between two floor areas and between different rooms due to the varying distances of sampled surfaces from potential BFR sources...
February 2018: Chemosphere
Reilly P Musselman, Sean Bennett, Wenbin Li, Muhammad Mamdani, Tara Gomes, Carl van Walraven, Robin Boushey, Omar Al-Obeed, Mohammed Al-Omran, Rebecca C Auer
BACKGROUND: Recent studies have demonstrated an association between beta-blocker exposure and improved survival in multiple cancer types. We sought to investigate the effects of beta-blockers at the time of index surgery for breast, lung, and colorectal cancer. MATERIALS AND METHODS: Using linked data from a provincial cancer registry, we conducted a retrospective matched cohort study comparing disease-specific and overall survival between patients over age 64 exposed and not exposed to beta-blockers before and after index surgical resection for breast, lung and colorectal cancer between April 1st, 2002 and December 31st, 2010...
May 17, 2018: European Journal of Surgical Oncology
Ashwak M F Abu-Taleb, Randa S Abdelattef, Amina A Abdel-Hady, Farida H Omran, Lobna A El-Korashi, Hoda Abdel-Aziz El-Hady, Ahmed M El-Gebaly
H. pylori infection causes peptic ulcer, chronic gastritis, mucosa-associated lymphoid tissue lymphoma, and gastric carcinoma. It has several virulence factors such as cytotoxin-associated gene A( cagA ) and the induced by contact with epithelium antigen ( iceA ). We aimed to explore the relationship between cagA and iceA of H. pylori and gastrointestinal diseases. One hundred and eighteen patients who attended Gastrointestinal Endoscopy Unit at Zagazig University Hospitals, Egypt, were included in this study...
2018: International Journal of Microbiology
Muzammil H Syed, Mohamad A Hussain, Zeyad Khoshhal, Konrad Salata, Beidaa Altuwaijri, Bertha Hughes, Norah Alsaif, Charles de Mestral, Subodh Verma, Mohammed Al-Omran
BACKGROUND: Rates of hospital readmission following surgery can serve as a marker for quality of care. The aim of this study was to establish the rates and causes of readmission and emergency department visits after vascular surgery and to understand how these patients are managed. METHODS: We conducted a prospective observational cohort study including all inpatients who underwent major vascular surgery between September 2015 and June 2016 at a tertiary vascular care centre in Toronto...
June 1, 2018: Canadian Journal of Surgery. Journal Canadien de Chirurgie
Zohreh Zal, Arash Ghasemi, Shima Azizi, Hossein Asgarian-Omran, Azadeh Montazeri, Seyed Jalal Hosseinimehr
BACKGROUND: Ionizing radiation induces DNA damage on normal cell results in apoptosis and cell deaths. OBJECTIVES: The radioprotective effects of cerium oxide nanoparticles (CNPs) on genotoxicity, apoptosis and necrosis induced by ionizing radiation (IR) in human normal lymphocytes as highly radiosensitive cells were investigated. MATERIALS AND METHODS: Lymphocytes were pretreated with CNPs at different concentrations and were exposure to IR...
May 27, 2018: Current Radiopharmaceuticals
Ahmed Maged, Mohamed Nagy, Ahmed Elhalwagy, Hoda Abd-ElAAl, Maged Almohamady, Aly Abdelhafez, Ahmed AlSawaf, Khalid Omran, Hala Nabil, Radwa Fahmy, Heba Wageih
Objectives to compare the interrupted subcuticular skin closure with continuous one in obese women undergoing cesarean delivery.
May 27, 2018: Journal of Maternal-fetal & Neonatal Medicine
Mohamad A Hussain, Mohammed Al-Omran, Mark A Creager, Sonia S Anand, Subodh Verma, Deepak L Bhatt
Peripheral artery disease (PAD) affects over 200 million people globally and is a cause of significant morbidity, mortality, and disability due to limb loss. Although secondary prevention with antithrombotic therapy is a mainstay of treatment to prevent adverse cardiovascular events, PAD patients are often undertreated with antithrombotic agents. Furthermore, there is a paucity of high-quality data from randomized controlled trials of PAD patients, leading to wide variations in clinical practice and guideline recommendations...
May 29, 2018: Journal of the American College of Cardiology
Rania S Nageeb, Nahed Shehta, Ghada S Nageeb, Alaa A Omran
Background: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the upper extremity. The aim of this study is to evaluate the body mass index (BMI) and vitamin D levels in CTS patients. Methods: The current study was conducted at Zagazig University Hospitals. It included 50 CTS patients and 50 controls. Clinical assessment was carried out to exclude symptoms and signs of neuropathy. Laboratory investigations including vitamin D levels, glycosylated hemoglobin, liver, and kidney function were carried out for every participant...
2018: The Egyptian journal of neurology, psychiatry and neurosurgery
Ali Barah, Ahmed Omar, Ayman El-Menyar, Omran Almokdad, Ahmed Sayedin, Ala Alsherbini, Ahmed Almuzrakshi, Hatem Khalaf, Hassan Al-Thani
INTRODUCTION: Various transarterial embolotherapies for different hepatic etiologies are performed through the celiac axis (CA). However, this pathway is not always patent due to the extensive stenosis or occlusion of the origin of CA. In such situations, the pancreaticoduodenal arcades (PDAs) catheterization is the main alternative to gain access to the hepatic arteries as demonstrated in clinical studies. PRESENTATION OF CASE: We report two cases of life-threating hepatic hemorrhage indicated for emergency transarterial embolization (TAE)...
April 11, 2018: International Journal of Surgery Case Reports
Mohamed El Kassas, Mohamed Alboraie, Dalia Omran, Mohamed Salaheldin, Mohamed Naguib Wifi, Mohamed ElBadry, Adel El Tahan, Sameera Ezzat, Enass Moaz, Amir M Farid, Heba Omar, Mahmoud Abouelkhair, Shimaa Afify, Kadry Elsaeed, Yehia Shazly, Wahid Doss, Gamal Esmat
BACKGROUND: A large Egyptian treatment program for HCV was launched in 2014 after the introduction of direct-acting antiviral agents (DAAs). This program depended mainly on establishing specialized independent centres for HCV treatment. These centres represent the major strengths in the Egyptian model of care, as they provide integrated care for HCV patients and have enabled Egypt to treat more than one million patients in 3 years. The New Cairo Viral Hepatitis Treatment Center (NCVHTC) is an example of these specialized centres...
May 14, 2018: Expert Review of Gastroenterology & Hepatology
Majid Bagheri Hosseinabadi, Siavash Etemadinezhad, Narges Khanjani, Omran Ahmadi, Hemat Gholinia, Mina Galeshi, Seyed Ehsan Samaei
Background: This study was designed to investigate job satisfaction and its relation to perceived job stress among hospital nurses in Babol County, Iran. Methods: This cross-sectional study was conducted on 406 female nurses in 6 Babol hospitals. Respondents completed the Minnesota Satisfaction Questionnaire (MSQ), the health and safety executive (HSE) indicator tool and a demographic questionnaire. Descriptive, analytical and structural equation modeling (SEM) analyses were carried out applying SPSS v. 22 and AMOS v...
2018: Health Promotion Perspectives
Thomas E Pidgeon, Charmilie Chandrakumar, Yasser Al Omran, Christopher Limb, Rachel Thavayogan, Buket Gundogan, Kiron Koshy, Amelia White, Alex Fowler, Riaz Agha
Introduction: The Academic Surgical Collaborative (ASC) is a trainee research collaborative (TRC) formed in the UK in October 2014. Three years on, the achievements are presented along with advice for emerging and established TRCs. Methods: A retrospective review of internal, member-maintained ASC records was conducted. Membership numbers, PubMed indexed publications, presentations and prizes awarded were all calculated over time. Google Scholar was used to calculate citations per ASC publication...
April 2018: Annals of Medicine and Surgery
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