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https://www.readbyqxmd.com/read/28319741/influence-of-sampling-approach-on-concentrations-of-legacy-and-novel-brominated-flame-retardants-in-indoor-dust
#1
Layla Salih Al-Omran, Stuart Harrad
The study investigates the impact of sampling method on the concentrations of PBDEs (BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154, BDE-183, and BDE-209) and NBFRs (PBEB, EH-TBB, BEH-TEBP, BTBPE and DBDPE) in indoor dust. A total of 36 dust samples were collected from 12 homes in Birmingham, UK (3 samples per home comprising researcher collected dust - both RCD from the living room (RCDL) and bedroom (RCDB), with an additional householder vacuum dust sample - HHVD). BDE-209 was the predominant compound, with average concentrations of 2642, 2336 and 2634 ng/g in RCDL, RCDB and HHVD respectively...
February 22, 2017: Chemosphere
https://www.readbyqxmd.com/read/28319414/preparation-and-characterization-of-zno-nanoparticles-coated-by-chitosan-linoleic-acid-fungal-growth-and-biofilm-assay
#2
S Barad, M Roudbary, A Nasrollahi Omran, M Porgham Daryasari
INTRODUCTION: This study has been carried out on reviewing the use of new synthetic component of zinc oxide nanoparticles (ZnO NPs) coated by Chitosan-linoleic acid (CS-LA) and to assess Minimum inhibitory concentration (MIC) of nanoparticles on clinical samples and biofilm formation in vitro. MATERIALS AND METHODS: At first the synthesized ZnO NPs coated by CS-LA were identified with X-ray powder diffraction (XRD), Scanning electron microscope (SEM), Transmission electron microscope (TEM) and Fourier Transform Infrared Spectroscopy analysis (FTIR)...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28316063/endothelial-long-non-coding-rnas-regulated-by-oxidized-ldl
#3
Krishna K Singh, Pratiek N Matkar, Yi Pan, Adrian Quan, Vijay Gupta, Hwee Teoh, Mohammed Al-Omran, Subodh Verma
Oxidized low-density lipoprotein (oxLDL) plays a central role in the pathogenesis of atherosclerosis, in part via an effect to promote endothelial dysfunction. In the present study, we evaluated the expression profiles of long non-coding RNAs (lncRNAs) and protein-coding mRNAs in endothelial cells following oxLDL stimulation. LncRNAs and mRNAs from human umbilical vein endothelial cells (HUVECs) were profiled with the Arraystar Human lncRNA Expression Microarray V3.0 following 24 h of oxLDL treatment (100 µg/mL)...
March 18, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28315440/optimized-production-and-characterization-of-a-detergent-stable-protease-from-lysinibacillus-fusiformis-c250r
#4
REVIEW
Sondes Mechri, Mouna Kriaa, Mouna Ben Elhoul Berrouina, Maroua Omrane Benmrad, Nadia Zaraî Jaouadi, Hatem Rekik, Khelifa Bouacem, Amel Bouanane-Darenfed, Alif Chebbi, Sami Sayadi, Mohamed Chamkha, Samir Bejar, Bassem Jaouadi
In this study, we aimed to optimize the cultural and nutritional conditions for protease production by Lysinibacillus fusiformis strain C250R in submerged fermentation process using statistical methodology. The most significant factors (gruel, wheat bran, yeast extract, and FeSO4) were identified by Plackett-Burman design. Response surface methodology (RSM) was used to determine the optimum levels of the screened factors and their interaction. Under the optimized conditions, protease yield 3100U/mL was 4.5 folds higher than those obtained by the use of the initial conditions (680U/ml)...
March 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28306177/frequency-and-functional-characterization-of-exhausted-cd8-t-cells-in-chronic-lymphocytic-leukemia
#5
Saeid Taghiloo, Esmaeil Allahmoradi, Mohsen Tehrani, Hadi Hossein-Nataj, Ramin Shekarriz, Ghasem Janbabaei, Saeid Abediankenari, Hossein Asgarian-Omran
OBJECTIVES: The phenotypic and functional properties of Tim-3+/PD-1+/CD8+ cells as exhausted T-cells were investigated in chronic lymphocytic leukemia (CLL). METHODS: Frequency of CD8+/Tim-3+/PD-1+ exhausted cells was determined by flow cytometry. For functional analysis, magnetic beads isolated CD8+ T-cells were stimulated with PHA and PMA/ionocymin to assess their proliferative responses and cytokine production by MTT and ELISA, respectively. Cytotoxic activity of isolated CD8+ T-cells was determined using CD107a degranulation assay...
March 17, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/28275519/sildenafil-citrate-in-combination-with-tamsulosin-versus-tamsulosin-monotherapy-for-management-of-male-lower-urinary-tract-symptoms-due-to-benign-prostatic-hyperplasia-a-randomised-double-blind-placebo-controlled-trial
#6
Amr Fawzi, Mostafa Kamel, Emad Salem, Esam Desoky, Mohamed Omran, Hazem Elgalaly, Ahmed Sakr, Aref Maarouf, Salem Khalil
OBJECTIVE: To assess the additive effect of sildenafil citrate to tamsulosin in the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia (LUTS/BPH) in men with or without erectile dysfunction (ED). PATIENTS AND METHODS: In all, 150 men with untreated LUTS/BPH with or without ED were randomised to receive sildenafil 25 mg once daily (OD) or placebo OD (night time) combined with tamsulosin 0.4 mg OD (day time) for 6 months. Changes from pre-treatment scores in International Prostate Symptom Score (IPSS), IPSS-quality of life (QoL) score, maximum urinary flow rate (Qmax), and the five-item version of the International Index of Erectile Function questionnaire (IIEF-5) were assessed at 3 and 6 months...
March 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/28271684/methylene-tetrahydrofolate-reductase-gene-polymorphism-is-associated-with-severity-of-liver-steatosis-in-chronically-infected-patients-with-hcv-genotype-4
#7
Reham M Dawood, Eman M Mahmoud, Marwa K Ibrahim, Noha G Bader El Din, Ahmed Aboul-Enein, Naglaa Zayed, Yasmine S El Abd, Hadeel G Eldeen, Rasha Eletreby, Marwa Elsharkawy, Moataza Omran, Reem El-Shenawy, Sayed A Fayed, Mostafa K El Awady
BACKGROUND: Methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism was reported as a genetic variant in liver steatosis and fibrosis. This is a study of the association between MTHFR C677T polymorphism and HCV core with severity of steatosis in HCV GT4 patients. METHODS: 111 HCV patients and 112 control subjects were recruited. Polymorphism was detected by RFLP analysis, core Ag was detected by ELISA. RESULTS: Combined HCV infection and MTHFR C677T polymorphism increases the risk to develop steatosis by 3...
March 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28265787/isolation-and-characterisation-of-an-enterocin-p-producing-enterococcus-lactis-strain-from-a-fresh-shrimp-penaeus-vannamei
#8
Olfa Ben Braïek, Hamdi Ghomrassi, Paola Cremonesi, Stefano Morandi, Yannick Fleury, Patrick Le Chevalier, Khaled Hani, Omrane Bel Hadj, Taoufik Ghrairi
Screening for lactic acid bacteria (LAB) from fresh shrimp samples (Penaeus vannamei) collected from retail seafood markets in the Tunisian's coast, resulted in the isolation of an Enterococcus strain termed Q1. This strain was selected for its antagonistic activity against pathogenic bacteria such as Listeria monocytogenes, Pseudomonas aeruginosa, Lactococcus garvieae and against fungi (Aspergillus niger and Fusarium equiseti). The Q1 strain was characterised using standard morphological and biochemical tests, growth assays at different temperatures, pH and salinity...
March 7, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/28264849/genetic-diversity-and-in-vitro-antifungal-susceptibility-of-200-clinical-and-environmental-aspergillus-flavus-isolates
#9
Mojtaba Taghizadeh-Armaki, Mohammad Taghi Hedayati, Saham Ansari, Saeed Mahdavi Omran, Sasan Saber, Haleh Rafati, Jan Zoll, Henrich A van der Lee, Willem J G Melchers, Paul E Verweij, Seyedmojtaba Seyedmousavi
Aspergillus flavus has been frequently reported as the leading cause of invasive aspergillosis in certain tropical and sub-tropical countries.Two hundred A. flavus strains originating from clinical and environmental sources and collected between 2008 and 2015 were phylogenetically identified at the species level by analyzing partial β-tubulin and calmodulin genes. In vitro antifungal susceptibility testing was performed against antifungals using the EUCAST (European Committee on Antimicrobial Susceptibility Testing) broth microdilution method...
March 6, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28257607/dync2h1-mutation-causes-jeune-syndrome-and-recurrent-lung-infections-associated-with-ciliopathy
#10
Nagehan Emiralioglu, Julia Wallmeier, Heike Olbrich, Heymut Omran, Ugur Ozcelik
Asphyxiating thoracic dystrophy, also known as Jeune syndrome, is included in a group of syndromic skeletal ciliopathies associated with mutations in genes encoding proteins involved in the formation or function of motile cilia. Herein, we report a 6-month-old male admitted to hospital with recurrent lung infections, thoracic dystrophy, and respiratory distress that was diagnosed as Jeune syndrome; DYNC2H1 mutation was detected via genetic analysis and ciliary dysfunction was noted via high-speed video microscopy...
March 3, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28254648/identification-of-a-novel-cntnap1-mutation-causing-arthrogryposis-multiplex-congenita-with-cerebral-and-cerebellar-atrophy
#11
Shenela Lakhani, Ryan Doan, Mariam Almureikhi, Jennifer N Partlow, Muna Al Saffar, Mahmoud F Elsaid, Nada Alaaraj, A James Barkovich, Christopher A Walsh, Tawfeg Ben-Omran
Arthrogryposis multiplex congenital, the occurrence of multiple joint contractures at birth, can in some cases be accompanied by insufficient myelination of peripheral nerves, muscular hypotonia, reduced tendon reflexes, and respiratory insufficiency. Recently mutations in the CASPR/CNTN1 complex have been associated with similar severe phenotypes and CNTNAP1 gene mutations, causing loss of the CASPR protein, were shown to cause severe, prenatal onset arthrogryposis multiplex congenita in four unrelated families...
February 27, 2017: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/28240516/transarterial-chemoembolization-combined-with-either-radiofrequency-or-microwave-ablation-in-management-of-hepatocellular-carcinoma
#12
Ashraf Omar Abdelaziz, Ahmed Hosni Abdelmaksoud, Mohamed Mahmoud Nabeel, Hend Ibrahim Shousha, Ahmed Abdelmonem Cordie, Sherif Hamdy Mahmoud, Eman Medhat, Dalia Omran, Tamer Mahmoud Elbaz
Introduction: Local ablative therapy and trans arterial chemoembolization (TACE) are applied to ablate non resectable hepatocellular carcinoma (HCC). Combination of both techniques has proven to be more effective. We aimed to study combined ablation techniques and assess survival benefit comparing TACE with radiofrequency (RFA) versus TACE with microwave (MWA) techniques. Methods: We retrospectively studied 22 patients who were ablated using TACE-RFA and 45 with TACE-MWA. All were classified as Child A-B and lesions did not exceed 5 cm in diameter...
January 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28230497/better-experimental-screening-and-treatment-for-primary-ciliary-dyskinesia-the-fp7-bestcilia-project
#13
K Kyriacou, P K Yiallouros, P Kouis, S I Papatheodorou, H Omran
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28229197/minimally-invasive-percutaneous-nephrolithotomy-vs-standard-pcnl-for-management-of-renal-stones-in-the-flank-free-modified-supine-position-single-center-experience
#14
Ahmed Sakr, Emad Salem, Mostafa Kamel, Esam Desoky, Ahmed Ragab, Mohamed Omran, Amr Fawzi, Ashraf Shahin
To assess the safety and efficacy of minimally invasive percutaneous nephrolithotomy (mPCNL) as compared to standard PCNL (sPCNL) for management of 2-3-cm renal stones in the flank-free modified supine position. Between September 2010 and December 2013, 150 patients (168 renal units) with 2-3-cm renal stones were prospectively randomized into two treatment groups; Group A (75 patients/87 renal units) treated by mPCNL and Group B (75 patients/81 renal units) treated by sPCNL. In both groups, the patients were placed in the flank-free modified supine position...
February 22, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28225826/assessing-mycoplasma-contamination-of-cell-cultures-by-qpcr-using-a-set-of-universal-primer-pairs-targeting-a-1-5-kb-fragment-of-16s-rrna-genes
#15
Audrey Jean, Florence Tardy, Omran Allatif, Isabelle Grosjean, Bariza Blanquier, Denis Gerlier
Mycoplasmas (a generic name for Mollicutes) are a predominant bacterial contaminant of cell culture and cell derived products including viruses. This prokaryote class is characterized by very small size and lack of a cell wall. Consequently, mycoplasmas escape ultrafiltration and visualization under routine microscopic examination, hence the ease with which cells in culture can be contaminated, with routinely more than 10% of cell lines being contaminated. Mycoplasma are a formidable threat both in fundamental research by perverting a whole range of cell properties and functions and in the pharmacological use of cells and cell derived products...
2017: PloS One
https://www.readbyqxmd.com/read/28215464/patients-with-intracranial-bleeding-and-atrial-fibrillation-treated-with-left-atrial-appendage-occlusion-results-from-the-amplatzer-cardiac-plug-registry
#16
Apostolos Tzikas, Xavier Freixa, Laura Llull, Sameer Gafoor, Samera Shakir, Heyder Omran, George Giannakoulas, Sergio Berti, Gennaro Santoro, Joelle Kefer, Adel Aminian, Steffen Gloekler, Ulf Landmesser, Jens Erik Nielsen-Kudsk, Ignacio Cruz-Gonzalez, Prapa Kanagaratnam, Fabian Nietlispach, Reda Ibrahim, Horst Sievert, Wolfgang Schillinger, Jai-Wun Park, Bernhard Meier, Haralampos Karvounis
BACKGROUND: In patients with non-valvular atrial fibrillation (NVAF), intracranial bleeding (ICB) constitutes a very challenging situation in which the rate of both ischemic and hemorrhagic events is increased. In these patients, left atrial appendage occlusion (LAAO) might represent a very valid alternative. OBJECTIVES: To investigate the procedural safety and long-term outcome of patients undergoing LAAO therapy due to previous ICB. METHODS: Data from the Amplatzer Cardiac Plug multicenter registry on 1047 consecutive patients were analyzed...
February 13, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28170060/abc-om-farmakologisk-symtomlindring-i-livets-slutskede
#17
Meis Omran, Staffan Lundström
No abstract text is available yet for this article.
February 3, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28165788/the-hairdryer-a-useful-adjunct-to-achieving-peripheral-venous-access
#18
Yasser Al Omran, Hannah Irvine, Alice Freebairn
No abstract text is available yet for this article.
February 2, 2017: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/28164635/microrna-122-as-a-novel-non-invasive-marker-of-liver-fibrosis-in-hepatitis-c-virus-patients
#19
Ahmed A S Omran, Khalid S Osman, Hanan M Kamel, Emad A Abdel-Naem, Dalia E El-Deen Hasan
BACKGROUND: Noninvasive evaluation of hepatic fibrosis is a growing scientific effort in medicine and is of particular interest as early diagnosis is important for the timely prevention and treatment of liver fibrosis and cirrhosis. Non-invasive markers of liver fibrosis have recently been developed as an alternative to liver biopsy. Aim of the work: The aim of this study was to assess the diagnostic value of serum microRNA 122 in Egyptian chronic hepatitis C virus infected patients. This may be a useful tool as a non invasive diagnostic test to detect early stages of fibrosis in comparison to 4 non invasive indexes (APRI, Forns, FIB-4, and FI) vs...
July 1, 2016: Clinical Laboratory
https://www.readbyqxmd.com/read/28139205/the-putative-role-of-autophagy-in-the-pathogenesis-of-abdominal-aortic-aneurysms
#20
REVIEW
Azza Ramadan, Mohammed Al-Omran, Subodh Verma
Abdominal aortic aneurysms (AAA) are a significant cause of worldwide mortality and morbidity. While the histopathological characteristics of AAA are well documented, the cellular and molecular mechanisms involved in the pathogenesis of AAA are not entirely understood. Autophagy is a highly conserved basal cellular process in eukaryotic cells that involves the turnover of organelles and proteins. It is also activated as an adaptive response to stressful conditions to promote cell survival. While autophagy typically promotes pro-survival processes, it can sometimes lead to cellular demise...
February 2017: Atherosclerosis
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