keyword
https://read.qxmd.com/read/38643488/antimicrobial-resistance-and-carbapenemase-dissemination-in-pseudomonas-aeruginosa-isolates-from-libyan-hospitals-a-call-for-surveillance-and-intervention
#1
JOURNAL ARTICLE
Nasrin K Gadaime, Randa N Haddadin, Asem A Shehabi, Intisar N Omran
Pseudomonas aeruginosa is a multidrug-resistant bacterium capable of forming biofilms. This study aimed to assess resistance of clinical isolates from Libyan hospitals to antipseudomonal antibiotics, the prevalence of selected extended-spectrum β-lactamases and carbapenemase genes among these isolates, and the microorganisms' capacity for alginate and biofilm production. Forty-five isolates were collected from four hospitals in Benghazi and Derna, Libya. Antimicrobial susceptibility was determined using agar disc diffusion...
December 31, 2024: Libyan Journal of Medicine
https://read.qxmd.com/read/38639373/predicting-outcomes-following-lower-extremity-endovascular-revascularization-using-machine-learning
#2
JOURNAL ARTICLE
Ben Li, Badr Aljabri, Raj Verma, Derek Beaton, Mohamad A Hussain, Douglas S Lee, Duminda N Wijeysundera, Charles de Mestral, Muhammad Mamdani, Mohammed Al-Omran
BACKGROUND: Lower extremity endovascular revascularization for peripheral artery disease carries nonnegligible perioperative risks; however, outcome prediction tools remain limited. Using machine learning, we developed automated algorithms that predict 30-day outcomes following lower extremity endovascular revascularization. METHODS AND RESULTS: The National Surgical Quality Improvement Program targeted vascular database was used to identify patients who underwent lower extremity endovascular revascularization (angioplasty, stent, or atherectomy) for peripheral artery disease between 2011 and 2021...
April 19, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38637644/a-new-fluorescence-probe-for-sofosbuvir-analysis-in-dosage-form-and-spiked-human-plasma
#3
JOURNAL ARTICLE
Mohamed S Nasr, Wael Talaat, Samir Morshedy, Mohamed M Y Kaddah, Gamal Omran, Reda M Keshk
A simple, rapid, and low-cost technique was developed to allow reliable analysis of the anti-hepatitis C drug sofosbuvir in bulk, tablet form, and spiked human plasma. This method depends on the ability of sofosbuvir to quench the fluorescence of the newly synthesized 2-amino-3-cyano-4,6-dimethylpyridine (reagent 3). Elemental analysis and spectral data were used to validate the structure of the synthesized reagent. The newly synthesized reagent exhibited a satisfactory level of fluorescence emission at 365 nm after excitation at 247 nm...
April 2024: Luminescence: the Journal of Biological and Chemical Luminescence
https://read.qxmd.com/read/38636702/reserpine-induced-rat-model-for-depression-behavioral-physiological-and-pet-based-dopamine-receptor-availability-validation
#4
JOURNAL ARTICLE
Lidia Miguel Telega, Raissa Berti, Ganna Blazhenets, Lisa-Charlotte Domogalla, Nils Steinacker, M Aymen Omrane, Philipp T Meyer, Volker A Coenen, Ann-Christin Eder, Máté D Döbrössy
BACKGROUND: Reserpine (RES), a Vesicular Monoamine Transporter 2 (VMAT2 ) inhibitor agent, has been used in preclinical research for many years to create animal models for depression and to test experimental antidepressant strategies. Nevertheless, evidence of the potential use and validity of RES as a chronic pharmacological model for depression is lacking, and there are no comprehensive studies of the behavioral effects in conjunction with molecular outcomes. METHODS: Experiment 1...
April 16, 2024: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://read.qxmd.com/read/38635403/the-relationship-between-environmentally-induced-emotion-and-memory-for-a-naturalistic-virtual-experience
#5
JOURNAL ARTICLE
Aria S Petrucci, Cade McCall, Guy Schofield, Victoria Wardell, Omran K Safi, Daniela J Palombo
Emotional stimuli (e.g. words, images) are often remembered better than neutral stimuli. However, little is known about how memory is affected by an environmentally induced emotional state (without any overtly emotional occurrences) - the focus of this study. Participants were randomly assigned to discovery ( n  = 305) and replication ( n  = 306) subsamples and viewed a desktop virtual environment before rating their emotions and completing objective (i.e. item, temporal-order, duration) and subjective (e...
April 18, 2024: Cognition & Emotion
https://read.qxmd.com/read/38633180/assessment-of-some-toxic-elements-co-cr-mn-se-and-as-in-muscle-offal-hair-and-blood-of-camels-camelus-dromedaries-and-their-risk-assessment
#6
JOURNAL ARTICLE
Ahmed M A Meligy, Waleed R El-Ghareeb, Sherief M Abdel-Raheem, Hesham A A Ismail, Wageh S Darwish, Mahmoud Kandeel, Ahmed E Alfifi, Saad S Al-Shokair, Mohamed A Hussein
BACKGROUND: Camel meat tainted with heavy metals or trace elements may pose a health risk to consumers. Heavy metal contamination poses a severe danger due to both their toxicity and bioaccumulation in the food chain. AIM: To estimate the residual levels of heavy metals (Co, Cr, Mn, Se, and As) in muscle, liver, kidney, hair, and serum of three camel breeds (Magaheem, Maghateer, and Wadha) collected from Al-Omran abattoir, Al-Ahsa, Saudi Arabia. METHODS: A total of 225 tissue samples (muscles, liver, kidney, serum, and hair) were taken and analyzed using an Atomic Absorption Spectrophotometer...
January 2024: Open Veterinary Journal
https://read.qxmd.com/read/38626355/recessively-inherited-deficiency-of-secreted-wfdc2-he4-causes-nasal-polyposis-and-bronchiectasis
#7
JOURNAL ARTICLE
Gerard W Dougherty, Lawrence E Ostrowski, Tabea Nöthe-Menchen, Johanna Raidt, Andre Schramm, Heike Olbrich, Weining Yin, Patrick R Sears, Hong Dang, Amanda J Smith, Achim G Beule, Rim Hjeij, Niels Rutjies, Eric G Haarman, Saskia M Maas, Thomas W Ferkol, Peadar G Noone, Kenneth N Olivier, Diana C Bracht, Pascal Barbry, Laure-Emmanuelle Zaragosi, Morgane Fierville, Sabine Kliesch, Kai Wohlgemuth, Julia König, Sebastian George, Niki T Loges, Agathe Ceppe, Matthew R Markovetz, Hong Luo, Ting Guo, Hoda Rizk, Tarek Eldesoky, Katrin Dahlke, Karsten Boldt, Marius Ueffing, David B Hill, Yuan-Ping Pang, Michael R Knowles, Maimoona A Zariwala, Heymut Omran
RATIONALE: Bronchiectasis is a pathological dilatation of the bronchi in the respiratory airways associated with environmental or genetic causes (e.g., cystic fibrosis, primary ciliary dyskinesia and primary immunodeficiency disorders), but most cases remain idiopathic. OBJECTIVES: To identify novel genetic defects in unsolved cases of bronchiectasis presenting with severe rhinosinusitis, nasal polyposis, and pulmonary Pseudomonas aeruginosa infection. METHODS: DNA was analyzed by next-generation or targeted Sanger sequencing...
April 16, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38623443/achieving-bratz-doll-look-with-lip-fillers-a-prospective-observational-study-on-blunt-cannula-techniques
#8
JOURNAL ARTICLE
Kamal Alhallak, Dima Omran, Salem Tomi
BACKGROUND: This study aims to evaluate the efficacy and safety of a blunt cannula technique using hyaluronic acid fillers for achieving the Bratz doll lip aesthetic, characterized by enhanced volume and sharp definition. METHODS: Thirty volunteers, 22-40 years of age, were selected based on specific inclusion criteria at Albany Cosmetic and Laser Center for 6 months. The technique involved precise filler injections using a Steriglide blunt cannula. Pre- and postprocedure measurements of lip dimensions and angular changes were meticulously documented and analyzed using IBM SPSS Statistics software...
April 2024: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38621636/predicting-the-need-for-subclavian-artery-revascularization-in-thoracic-endovascular-aortic-repair-a-systematic-review-and-meta-analysis
#9
REVIEW
Tariq Alanezi, Abdulmajeed Altoijry, Sultan AlSheikh, Husain Al-Mubarak, Musaad Alhamzah, Faris Alomran, Omer Abdulrahim, Badr Aljabri, Elisa Greco, Mohamad A Hussain, Mohammed Al-Omran
OBJECTIVES: This systematic review and meta-analysis aims to investigate the effectiveness of left subclavian artery revascularization compared to non-revascularization in thoracic endovascular aortic repair, and to summarize the current evidence on its indications. METHODS: A computerized search was conducted across multiple databases, including MEDLINE, SCOPUS, Cochrane Library, and Web of Science, for studies published up to November 2023. Study selection, data abstraction, and quality assessment (using the Newcastle-Ottawa Scale) were independently conducted by two reviewers, with a third author resolving discrepancies...
April 13, 2024: Journal of Vascular Surgery
https://read.qxmd.com/read/38619554/expression-of-concern-maternal-serum-homocysteine-and-uterine-artery-doppler-as-predictors-of-preeclampsia-and-poor-placentation
#10
Ahmed M Maged, Hany Saad, Hadeer Meshaal, Emad Salah, Suzy Abdelaziz, Eman Omran, Wesam S Deeb, Maha Katta
No abstract text is available yet for this article.
April 15, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38618753/tazarotene-is-as-effective-and-tolerable-as-imiquimod-in-the-treatment-of-verruca-plana-a-comparative-randomized-clinical-trial
#11
JOURNAL ARTICLE
Hagar Nofal, Fatma Omran, Basma ElKholy, Sara Nofal, Ahmad Nofal
BACKGROUND: Plane warts when multiple and recurrent present a therapeutic challenge acting as a source of reinfection causing frustration and affecting patient's quality of life. For lesions of large numbers in cosmetically significant sites, topical treatment is preferred to avoid potential sequelae. OBJECTIVES: To evaluate and compare the efficacy and tolerability of tazarotene 0.1% gel versus imiquimod 5% cream for the treatment of plane warts. METHODS: In a parallel three-arm randomized controlled trial, 60 patients were randomized into imiquimod, tazarotene or placebo groups...
April 15, 2024: Clinical and Experimental Dermatology
https://read.qxmd.com/read/38614162/external-validation-of-the-si-2-ncal-2-c-score-for-outcomes-following-cerebral-venous-thrombosis
#12
JOURNAL ARTICLE
Piers Klein, Liqi Shu, Erik Lindgren, Maria A de Winter, James E Siegler, Alexis N Simpkins, Satareh Salehi Omran, Mirjam R Heldner, Adam de Havenon, Mohamad Abdalkader, Sami Al Kasab, Christoph Stretz, Teddy Y Wu, Duncan Wilson, Syed Daniyal Asad, Eyad Almallouhi, Jennifer Frontera, Lindsey Kuohn, Aaron Rothstein, Ekaterina Bakradze, Nils Henninger, Adeel S Zubair, Richa Sharma, Deborah Kerrigan, Yasmin Aziz, Eva A Mistry, Mayte Sanchez van Kammen, Turgut Tatlisumak, Katarzyna Krzywicka, Diana Aguiar de Sousa, Katarina Jood, Thalia S Field, Shadi Yaghi, Jonathan M Coutinho, Thanh N Nguyen
OBJECTIVES: Prognostication for cerebral venous thrombosis (CVT) remains difficult. We sought to validate the SI2 NCAL2 C score in an international cohort. MATERIALS AND METHODS: The SI2 NCAL2 C score was originally developed to predict poor outcome (modified Rankin Scale (mRS) 3-6) at 6 months, and mortality at 30 days and 1 year using data from the International CVT Consortium. The SI2 NCAL2 C score uses 9 variables: the absence of any female-sex-specific risk factors, intracerebral hemorrhage, central nervous system infection, focal neurological deficits, coma, age, lower level of hemoglobin, higher level of glucose, and cancer...
April 11, 2024: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://read.qxmd.com/read/38602875/perilipin-membrane-integration-determines-lipid-droplet-heterogeneity-in-differentiating-adipocytes
#13
JOURNAL ARTICLE
Mario Majchrzak, Ozren Stojanović, Dalila Ajjaji, Kalthoum Ben M'barek, Mohyeddine Omrane, Abdou Rachid Thiam, Robin W Klemm
The storage of fat within lipid droplets (LDs) of adipocytes is critical for whole-body health. Acute fatty acid (FA) uptake by differentiating adipocytes leads to the formation of at least two LD classes marked by distinct perilipins (PLINs). How this LD heterogeneity arises is an important yet unresolved cell biological problem. Here, we show that an unconventional integral membrane segment (iMS) targets the adipocyte specific LD surface factor PLIN1 to the endoplasmic reticulum (ER) and facilitates high-affinity binding to the first LD class...
April 9, 2024: Cell Reports
https://read.qxmd.com/read/38601646/modeling-of-success-factors-of-using-pu-coats-in-concrete-construction-projects
#14
JOURNAL ARTICLE
Ahsan Waqar, Nasir Shafiq, Naraindas Bheel, Omrane Benjeddou, Nadhim Hamah Sor, Jong Wan Hu, Hadee Mohammed Najm, Hamad R Almujibah
Polyurea coatings are well recognized for their remarkable protective properties, making them highly appropriate for practical use in the field of concrete building. The use of polyurea coatings in the concrete building business is currently constrained, despite its prevalent application in industrialized nations. The limited use may be ascribed to ambiguities about the determinants of effective implementation in this particular setting, as well as the dearth of extensive study in the realm of new building materials...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38599293/development-and-evaluation-of-a-prediction-model-for-peripheral-artery-disease-related-major-adverse-limb-events-using-novel-biomarker-data
#15
JOURNAL ARTICLE
Ben Li, Rakan Nassereldine, Abdelrahman Zamzam, Muzammil H Syed, Muhammad Mamdani, Mohammed Al-Omran, Rawand Abdin, Mohammad Qadura
BACKGROUND: Prognostic tools for individuals with peripheral artery disease (PAD) remain limited. We developed prediction models for 3-year PAD related major adverse limb events (MALE) using demographic, clinical, and biomarker data previously validated by our group. METHODS: We performed a prognostic study using a prospectively recruited cohort of PAD patients (n = 569). Demographic/clinical data were recorded including sex, age, comorbidities, previous procedures, and medications...
April 8, 2024: Journal of Vascular Surgery
https://read.qxmd.com/read/38595635/cns-demyelination-syndromes-following-covid-19-vaccination-a-case-series
#16
Yasser Hamed, Abd-Elaziz Shokry, Khaled Mohamed Ali Shehata, Salma Mokhtar Osman, Khaled Saad, Safwat Salama Sawy, Emad Abdelrazzak, Omran Mohamed Abdelmola, Tarek Mansour
BACKGROUND AND OBJECTIVES: Although immunization against coronavirus disease 2019 (COVID-19) is ongoing, adverse reactions to these vaccinations have been observed in isolated cases. We aimed to report different neurological complications developed after COVID-19 vaccination. MATERIALS AND METHODS: In our case series study, we report all cases of CNS demyelination following COVID-19 immunization. Clinical evaluation, brain MRI, and CSF analysis for oligoclonal bands and IgG index were performed for all patients...
February 2024: Journal of Pharmacy & Bioallied Sciences
https://read.qxmd.com/read/38590835/obstructive-jaundice-caused-by-metastatic-neuroendocrine-tumor-of-the-ampulla-of-vater-in-a-young-adult-a-case-report
#17
Jaafar Alsalman, Abdulaziz Alqourain, Mohammed Alyousef, Omran Aldandan, Ibrahim Alzahrani
INTRODUCTION: Ampullary neuroendocrine tumors (NETs) are usually diagnosed in the 5th-6th decades of life, and no cases were reported in <20 years of age. We report a rare case, presenting at a very young age, of well-differentiated NET involving the ampulla of Vater with lymph node metastasis. CASE PRESENTATION: An 18-year-old man presented with a 3-month history of upper abdominal pain and jaundice. Abdominal ultrasound showed a dilated common bile duct, and endoscopic retrograde cholangiopancreatography revealed two duodenal polypoid lesions, one of them overlying the ampulla of Vater, with an erythematous and ulcerated surface...
2024: Case Reports in Gastroenterology
https://read.qxmd.com/read/38584274/burden-of-mendelian-disorders-in-a-large-middle-eastern-biobank
#18
JOURNAL ARTICLE
Waleed Aamer, Aljazi Al-Maraghi, Najeeb Syed, Geethanjali Devadoss Gandhi, Elbay Aliyev, Alya A Al-Kurbi, Omayma Al-Saei, Muhammad Kohailan, Navaneethakrishnan Krishnamoorthy, Sasirekha Palaniswamy, Khulod Al-Malki, Saleha Abbasi, Nourhen Agrebi, Fatemeh Abbaszadeh, Ammira S Al-Shabeeb Akil, Ramin Badii, Tawfeg Ben-Omran, Bernice Lo, Younes Mokrab, Khalid A Fakhro
BACKGROUND: Genome sequencing of large biobanks from under-represented ancestries provides a valuable resource for the interrogation of Mendelian disease burden at world population level, complementing small-scale familial studies. METHODS: Here, we interrogate 6045 whole genomes from Qatar-a Middle Eastern population with high consanguinity and understudied mutational burden-enrolled at the national Biobank and phenotyped for 58 clinically-relevant quantitative traits...
April 8, 2024: Genome Medicine
https://read.qxmd.com/read/38572277/open-repair-of-transverse-cervical-pseudoaneurysm
#19
Mohammed Dahman, Lina Abusulayman, Norah Alharbi, Faisal Joueidi, Omer Abdulrahim, Mohammed Al-Omran
A 40-year-old woman was referred to the vascular surgery clinic complaining of right shoulder pain and swelling secondary to blunt trauma 4 months ago. Computed tomography angiography showed a partially thrombosed supraclavicular pseudoaneurysm adjacent to the subclavian artery measuring 4.5 × 4 × 3.1 cm. Open repair surgery with resection of the pseudoaneurysm was successfully performed without injury to the capsule. Patient was stable and discharged 2 days later with no complications...
April 2024: Journal of Surgical Case Reports
https://read.qxmd.com/read/38569060/county-level-socio-environmental-factors-associated-with-stroke-mortality-in-the-united-states-a-cross-sectional-study
#20
JOURNAL ARTICLE
Pedro R V O Salerno, Issam Motairek, Weichuan Dong, Khurram Nasir, Neel Fotedar, Setareh S Omran, Sarju Ganatra, Omar Hahad, Salil V Deo, Sanjay Rajagopalan, Sadeer G Al-Kindi
We used machine learning methods to explore sociodemographic and environmental determinants of health (SEDH) associated with county-level stroke mortality in the USA. We conducted a cross-sectional analysis of individuals aged ≥15 years who died from all stroke subtypes between 2016 and 2020. We analyzed 54 county-level SEDH possibly associated with age-adjusted stroke mortality rates/100,000 people. Classification and Regression Tree (CART) was used to identify specific county-level clusters associated with stroke mortality...
April 3, 2024: Angiology
keyword
keyword
84668
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.