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Hayam Mahmoud Lotfy, Yasmin Rostom Omran
A novel, simple, rapid, accurate, and economical spectrophotometric method, namely absorptivity centering (a-Centering) has been developed and validated for the simultaneous determination of mixtures with partially and completely overlapping spectra in different matrices using either normalized or factorized spectrum using built-in spectrophotometer software without a need of special purchased program. Mixture I (Mix I) composed of Simvastatin (SM) and Ezetimibe (EZ) is the one with partial overlapping spectra formulated as tablets, while mixture II (Mix II) formed by Chloramphenicol (CPL) and Prednisolone acetate (PA) is that with complete overlapping spectra formulated as eye drops...
April 7, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Charles de Mestral, Konrad Salata, Mohamad A Hussain, Ahmed Kayssi, Mohammed Al-Omran, Graham Roche-Nagle
BACKGROUND: Early readmission to hospital after surgery is an omnipresent quality metric across surgical fields. We sought to understand the relative importance of hospital readmission among all health services received after hospital discharge. OBJECTIVE: The aim of this study was to characterize 30-day postdischarge cost and risk of an emergency department (ED) visit, readmission, or death after hospitalization for elective major vascular surgery. METHODS: This is a population-based retrospective cohort study of patients who underwent elective major vascular surgery - carotid endarterectomy, EVAR, open AAA repair, bypass for lower extremity peripheral arterial disease - in Ontario, Canada, between 2004 and 2015...
April 18, 2018: Annals of Surgery
Eman Omran, Mohamed El-Sharkawy, Akmal El-Mazny, Mohamed Hammam, Wafaa Ramadan, Dina Latif, Dalia Samir, Sherine Sobh
Purpose: The aim of the study was to evaluate the effect of clomiphene citrate on uterine artery blood flow using pulsed Doppler and endometrial and subendometrial micro vascularization using 3D power Doppler in unexplained infertility. Patients and methods: In a prospective observational study at a university teaching hospital, the mid-luteal (peri-implantation) endometrial thickness and volume, uterine artery pulsatility index (PI) and resistance index (RI), endometrial and subendometrial vascularization index (VI), flow index (FI), and vascularization flow index (VFI), and serum estradiol and progesterone levels were compared between natural and clomiphene citrate stimulated cycles in the same group of 50 patients with unexplained infertility...
2018: International Journal of Women's Health
Rita Hleihel, Behzad Khoshnood, Ingrid Dacklin, Hayssam Omran, Carine Mouawad, Zeina Dassouki, Marwan El-Sabban, Margret Shirinian, Caroline Grabbe, Ali Bazarbachi
BACKGROUND: Adult T-cell leukemia/lymphoma (ATL) is an aggressive malignancy secondary to chronic human T-cell lymphotropic virus 1 infection, triggered by the virally encoded oncoprotein Tax. The transforming activity and subcellular localization of Tax is strongly influenced by posttranslational modifications, among which ubiquitylation and SUMOylation have been identified as key regulators of the nuclear/cytoplasmic shuttling of Tax, as well as its ability to activate NF-κB signaling...
April 17, 2018: Retrovirology
Zohreh Koohini, Hadi Hossein-Nataj, Maryam Mobini, Aref Hosseinian-Amiri, Alireza Rafiei, Hossein Asgarian-Omran
Expression of T cell immunoglobulin and mucin-domain containing-3 (Tim-3) and programmed cell death-1 (PD-1) was studied on CD4+ T cells of patients with rheumatoid arthritis (RA). Association of Tim-3 and PD-1 expression with disease activity of RA patients was also addressed. A total of 37 RA patients and 31 sex- and age-matched healthy controls were included in this study. Disease activity of RA patients was determined by Disease Activity Score of 28 joints scoring system (DAS28). A three-color flow cytometry method was applied to determine the frequency of Tim-3+ /PD-1+ /CD4+ T cells...
April 7, 2018: Clinical Rheumatology
Basma A Omran, Hussein N Nassar, Nesreen A Fatthallah, A Hamdy, Einas H El-Shatoury, Nour Sh El-Gendy
AIMS: Since mycosynthesis of metal nanoparticles is advertised as a promising and eco- friendly approach. Thus, the present study aims to investigate the capability of Aspergillus brasiliensis ATCC 16404 for mycosynthesis of silver nanoparticles (AgNPs). METHODS AND RESULTS: One-factor-at-a-time-technique was used to study the effect of different physicochemical parameters; the reaction time, pH, temperature, different stirring rates, illumination and finally the different concentrations of silver nitrate and fungal biomass on the mycosynthesis of AgNPs...
April 6, 2018: Journal of Applied Microbiology
Eman F Omran, Hadeer Meshaal, Sarah M Hassan, Amira S Dieb, Hala Nabil, Hani Saad
BACKGROUND: Cesarean section rate has increased dramatically worldwide but there is still debate about the optimum operative technique of cesarean section. OBJECTIVE: The purpose of this study was to assess the effect of rectus muscle reapproximation at cesarean delivery on the postoperative pain. METHODS: This study was a prospective, double-blind, randomized controlled trial. It included 280 primigravidas, with a singleton pregnancy, who underwent elective lower segment cesarean section at term...
April 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
Akbar Hedayatizadeh-Omran, Reza Alizadeh-Navaei, Ghasem Janbabaei, Versa Omrani-Nava, Yahya Hasheminasab, Omolbanin Amjadi, Mohsen Tehrani
Gastric cancer has the fourth highest morbidity rate of all cancers worldwide. Genetic factors including alterations in oncogenes and tumor suppressor genes serve an important role in gastric cancer development and progression. The P53 gene acts as a tumor suppressor gene by regulating the cell cycle, DNA transcription and repair, apoptosis, senescence and genome stability. In addition to somatic P53 mutations in cancer development, germline polymorphisms are also involved in different malignancies. The polymorphism of P53 at codon 72 (Arg72Pro) is established as a common variant that increases susceptibility to various cancers...
May 2018: Biomedical Reports
Ahmed M Maged, Ali M El-Semary, Heba M Marie, Doaa S Belal, Ayman Hany, Mohammad A Taymour, Eman F Omran, Sahar M Y Elbaradie, Mohamed A Kamal Mohamed
OBJECTIVE: To test the hypothesis that there is a higher rate of unsuccessful induction of labor (IOL) in post-term obese pregnant women compared to non-obese ones. METHODS: In this prospective cohort study, 144 obese (BMI > 30) and 144 non-obese (BMI < 29.9) post-term (> 41 weeks) pregnant women were recruited. IOL was done by misoprostol or amniotomy and oxytocin infusion according to the Bishop score. Comparison of percentage of failed IOL in both groups (primary outcome) was performed by the Chi-test...
April 2, 2018: Archives of Gynecology and Obstetrics
Nguyen Lam Vuong, Abdelrahman Elshafay, Le Phuong Thao, Ahmed Ramadan Abdalla, Islam Ashraf Mohyeldin, Khaled Elsabaa, Esraa Salah Omran, Fuxun Yu, Kenji Hirayama, Nguyen Tien Huy
BACKGROUND: Primary spontaneous pneumothorax (PSP) remains a significant global health problem. Despite general agreement, an official algorithm for the management of PSP still does not exist. OBJECTIVES: Evaluating the efficacy of all available treatments in PSP. METHODS: A systematic search of 12 electronic databases was performed to identify all randomized controlled trials (RCTs) of any treatments in PSP. The primary endpoint was recurrence incidence; secondary were an immediate success, complication and hospitalization days...
April 2018: Respiratory Medicine
Abazar Ghorbani, Seyed Mehdi Razavi, Valli Ollah Ghasemi Omran, Hemmatollah Pirdashti
Nowadays, salinity has become an increasingly serious environmental issue that affects the growth and yield of a majority of plants. In the present work, the influences of Piriformospora indicia on gas exchange, water potential, osmolyte content, Na/K ratio and chlorophyll fluorescence of tomato plants under three salinity levels (0, 50, 100 and 150mM NaCl) and three time-course (5, 10 and 15 days after exposure to salt). Results indicated that P. indicia improves growth parameters of tomato under salinity...
March 25, 2018: Plant Biology
Ahmed Omran, Samah Eesai, Mostafa Ibrahim, Sonya El-Sharkawy
BACKGROUND: Pneumonia is still a leading cause of illness and death in infants worldwide. Lung ultrasound (LUS) is emerging as an extremely valuable non-ionizing radiation diagnostic tool in diagnosis and follow up of multiple pediatric pulmonary diseases. OBJECTIVE: To assess the applicability of LUS in diagnosis and follow up of community acquired pneumonia (CAP) in Egyptian infants younger than 1 year old. METHODS: LUS and chest X ray (CXR) were performed in 50 infants presented with clinical symptoms and signs suggestive of CAP within the first 6 hours of admission in our inpatient department, then follow up LUS was performed 5 days after admission...
March 23, 2018: Clinical Respiratory Journal
A J Mercer
The main feature of the epidemiological transition is a shift in the recorded causes of death from infectious diseases to other morbid conditions. This paper outlines modifications made to Omran's original model and stages of transition, and suggests that without a focus on aetiology and morbidity, these have been basically descriptive rather than explanatory, and potentially misleading because infections have been confirmed as causes of various chronic diseases. Common infections and related immune responses or inflammatory processes contribute to the multifactorial aetiology of morbid conditions that together make a substantial contribution to overall mortality, and infectious causation is suspected for many others because of strong evidence of association...
March 20, 2018: Epidemiology and Infection
Heyder Omran, Apostolos Tzikas, Horst Sievert, Frederike Stock
Percutaneous left atrial appendage occlusion was introduced as an alternative method for prevention of thromboembolism in patients with nonvalvular atrial fibrillation after extensive animal work in 2001. The first device was named Percutaneous Left Atrial Appendage Transcatheter Occlusion (PLAATO) and patented by the company Appriva. The device was invented by Michael Lesh, MD.
April 2018: Interventional Cardiology Clinics
Hadi Bazzazi, Mehrdad Aghaei, Ali Memarian, Hossein Asgarian-Omran, Nasser Behnampour, Yaghoub Yazdani
The Th17, Th1 and dual Th17/Th1 cells are important players in rheumatoid arthritis (RA) disease. To assess their roles, the frequency and impact of these cells were investigated in patients with different disease activity. In 14 new cases and 41 established RA patients in comparison with 22 healthy controls, the percentages of Th17, Th1 and dual Th17/Th1 cells were determined by flow-cytometry and their correlations were investigated with disease activity score (DAS28). Moreover, serum levels of IL-6 and IL-17 as inducer and functional cytokines for Th17 were investigated...
February 2018: Iranian Journal of Allergy, Asthma, and Immunology
Fatma Omrane, Imed Gargouri, Moncef Khadhraoui, Boubaker Elleuch, Denis Zmirou-Navier
BACKGROUND: Sfax is a very industrialized city located in the southern region of Tunisia where heavy metals (HMs) pollution is now an established matter of fact. The health of its residents mainly those engaged in industrial metals-based activities is under threat. Indeed, such workers are being exposed to a variety of HMs mixtures, and this exposure has cumulative properties. Whereas current HMs exposure assessment is mainly carried out using direct air monitoring approaches, the present study aims to assess health risks associated with chronic occupational exposure to HMs in industry, using a modeling approach that will be validated later on...
March 5, 2018: BMC Public Health
Hooman Hennessey, Elna Luckham, Ahmed Kayssi, Mark David Wheatcroft, Elisa Greco, Mohammed Al-Omran, John Harlock, Mohammad Qadura
OBJECTIVE: In the treatment of an infected aorta, open repair and replacement with a rifampin-impregnated Dacron vascular graft decrease the risk of prosthetic graft infections, with several protocols available in the literature. We hypothesize that the same holds true for endovascular aneurysm repair, and after studying and optimizing rifampin solution concentration and incubation period to maximize the coating process of rifampin on Dacron endovascular stent grafts (ESGs), we propose a rapid real-time perioperative protocol...
March 1, 2018: Journal of Vascular Surgery
Suha Omran, Susan Mcmillan
Background: Despite advances in cancer disease prevention, diagnosis, and treatment patients with cancer suffer from a variety of sometimes severe physical and psychological symptoms regardless of the stage of the disease. The aim is to determine the relationship of antecedent factors and mediating variables to the quality of life (QOL) of patients with cancer. Materials and Methods: The study included 341 patients with cancer and symptoms. Data collection used the Cancer Symptom Scale, State-Trait Anxiety Inventory, Centers for Epidemiologic Study-Depression, Cancer Behavior Inventory, Multidimensional Quality of Life Index, and a Demographic Form...
February 26, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
Jad Omran, Tariq Enezate, Obai Abdullah, Ashraf S Al-Dadah, Herbert D Aronow, Jihad Mustapha, Fadi Saab, Emmanouil S Brilakis, Ryan R Reeves, Deepak L Bhatt, Ehtisham Mahmud
BACKGROUND: A number of studies suggest that bivalirudin (BIV) is associated with similar efficacy but reduced bleeding when compared with unfractionated heparin (UFH) in patients undergoing peripheral vascular interventions (PVI). METHODS: A comprehensive literature search was conducted with the electronic databases MEDLINE, EMBASE and CENTRAL. These were queried to identify studies comparing BIV with UFH in PVI. Study endpoints included total bleeding events, major and minor bleeding events and procedural success...
January 31, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
Mohamad A Hussain, Subodh Verma, Mohammed Al-Omran
No abstract text is available yet for this article.
March 2018: Journal of Vascular Surgery
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