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Bispectral Index Elderly

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https://www.readbyqxmd.com/read/27903341/-the-application-of-conscious-sedation-with-a-small-dose-of-dexmedetomidine-and-sufentanil-in-elderly-patients-undergoing-multiple-intestinal-polyps-resection
#1
C M Shi, Y D Zhou, M Xu, X D Wang, L M Meng, X J Liu, X Y Guo
Objective: To explore the effectiveness and feasibility of conscious sedation with a low dose of dexmedetomidine and sufentanil during multiple intestinal polyps resection in elderly patients. Methods: Sixty elderly patients who underwent multiple intestinal polyps resection in Peking University Third Hospital from Janurary to May 2016 were randomly divided into dexmedetomidine group (D group, n=30) and propofol group (P group, n=30). There were 28 males and 32 females with a mean age of (70.4±4.5) years old (range: 65-80 years old)...
November 22, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27871553/fascia-iliaca-block-associated-only-with-deep-sedation-in-high-risk-patients-taking-p2y12-receptor-inhibitors-for-intramedullary-femoral-fixation-in-intertrochanteric-hip-fracture-a-series-of-3-cases
#2
Carlos Rodrigues Almeida, Emília Milheiro Francisco, Vítor Pinho-Oliveira, José Pedro Assunção
OBJECTIVE: We present a series of 3 cases in which the impact in outcome was, first of all, related to the capacity to offer early and safer treatment to some hip fracture high-risk patients using a fascia iliaca block (FIB; ropivacaine 0,5% 20 cc and mepivacaine 1,3% 15 cc, given 30 minutes before incision) associated only with deep sedation, contributing to better practice and outcome. CASE REPORTS: All elderly patients were American Society of Anesthesiologists IV patients, under P2Y12 receptor inhibitors, suffering from an intertrochanteric fracture, and purposed for intramedullary femoral fixation (IMF)...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27602075/safety-and-efficacy-of-etomidate-and-propofol-anesthesia-in-elderly-patients-undergoing-gastroscopy-a-double-blind-randomized-clinical-study
#3
Qing-Tao Meng, Chen Cao, Hui-Min Liu, Zhong-Yuan Xia, Wei Li, Ling-Hua Tang, Rong Chen, Meng Jiang, Yang Wu, Yan Leng, Chris C Lee
The aim of the present study is to compare the safety, efficacy and cost effectiveness of anesthetic regimens by compound, using etomidate and propofol in elderly patients undergoing gastroscopy. A total of 200 volunteers (65-79 years of age) scheduled for gastroscopy under anesthesia were randomly divided into the following groups: P, propofol (1.5-2.0 mg/kg); E, etomidate (0.15-0.2 mg/kg); P+E, propofol (0.75-1 mg/kg) followed by etomidate (0.075-0.1 mg/kg); and E+P, etomidate (0.075-0.01 mg/kg) followed by propofol (0...
September 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27220943/bispectral-index-monitoring-in-terminally-ill-patients-a-validation-study
#4
Anniek D Masman, Monique van Dijk, Joost van Rosmalen, Heleen J Blussé van Oud-Alblas, Erwin Ista, Frans P M Baar, Dick Tibboel
CONTEXT: If regular therapies cannot relieve symptoms sufficiently in the last days of life, continuous palliative sedation may serve to reduce consciousness. Sedation level can be measured with EEG monitoring with the bispectral index (BIS) monitor. OBJECTIVES: To determine the feasibility and validity of BIS monitoring in terminally ill patients. METHODS: In this prospective study, BIS registrations were performed in unconscious end-of-life patients admitted to a palliative care center...
August 2016: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/27152422/effects-of-single-low-dose-of-dexamethasone-before-noncardiac-and-nonneurologic-surgery-and-general-anesthesia-on-postoperative-cognitive-dysfunction-a-phase-iii-double-blind-randomized-clinical-trial
#5
Livia Stocco Sanches Valentin, Valeria Fontenelle Angelim Pereira, Ricardo S Pietrobon, Andre P Schmidt, Jean P Oses, Luis V Portela, Diogo O Souza, João Ricardo Nickenig Vissoci, Vinicius Fernando da Luz, Leticia Maria de Araujo de Souza Trintoni, Karen C Nielsen, Maria José Carvalho Carmona
UNLABELLED: Postoperative cognitive dysfunction (POCD) is a multifactorial adverse event most frequently in elderly patients. This study evaluated the effect of dexamethasone on POCD incidence after noncardiac and nonneurologic surgery. METHODS: One hundred and forty patients (ASA I-II; age 60-87 years) took part in a prospective phase III, double blind, randomized study involving the administration or not of 8 mg of IV dexamethasone before general anesthesia under bispectral index (BIS) between 35-45 or 46-55...
2016: PloS One
https://www.readbyqxmd.com/read/26928796/changes-in-first-postoperative-night-bispectral-index-after-daytime-sedation-induced-by-dexmedetomidine-or-midazolam-under-regional-anesthesia-a-randomized-controlled-trial
#6
Wen-fei Tan, Er-ya Miao, Feng Jin, Hong Ma, Huang-wei Lu
BACKGROUND AND OBJECTIVES: Supplementation of spinal anesthesia with various sedatives is a standard protocol to alleviate patient anxiety associated with the surgical procedure. We hypothesized that, compared with dexmedetomidine, midazolam might have a subtle influence on sleep quality after surgery following elective transurethral prostatic resection (TURP) in elderly male patients. METHODS: A randomized, double-blind, controlled trial was conducted at the First Hospital of China Medical University from July 2014 to January 2015...
May 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/26879014/changes-in-the-bispectral-index-in-response-to-loss-of-consciousness-and-no-somatic-movement-to-nociceptive-stimuli-in-elderly-patients
#7
Ning Yang, Yun Yue, Jonathan Z Pan, Ming-Zhang Zuo, Yu Shi, Shu-Zhen Zhou, Wen-Ping Peng, Jian-Dong Gao
BACKGROUND: Bispectral index (BIS) is considered very useful to guide anesthesia care in elderly patients, but its use is controversial for the evaluation of the adequacy of analgesia. This study compared the BIS changes in response to loss of consciousness (LOC) and loss of somatic response (LOS) to nociceptive stimuli between elderly and young patients receiving intravenous target-controlled infusion (TCI) of propofol and remifentanil. METHODS: This study was performed on 52 elderly patients (aged 65-78 years) and 52 young patients (aged 25-58 years), American Society of Anesthesiologists physical status I or II...
February 20, 2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/26621628/can-intraoperative-processed-eeg-predict-postoperative-cognitive-dysfunction-in-the-elderly
#8
Stacie Deiner, Xiaodong Luo, Jeffrey H Silverstein, Mary Sano
PURPOSE: Postoperative cognitive dysfunction (POCD) is a serious and costly complication of the elderly; even mild impairment has the potential to impact overall well being. Anesthesiologists continue to search for ways to manipulate intraoperative technique to optimize postoperative cognition in the elderly. Depth of anesthesia during surgery is an area that has shown some promise for short-term outcomes, such as delirium. However, excessive depth has both positive and negative associations with longer-term POCD...
December 1, 2015: Clinical Therapeutics
https://www.readbyqxmd.com/read/26521807/corrigendum-comparison-of-c%C3%A2-%C3%A2-for-propofol-remifentanil-target-controlled-infusion-and-bispectral-index-at-loss-of-consciousness-and-response-to-painful-stimulus-in-elderly-and-young-patients
#9
https://www.readbyqxmd.com/read/26500982/comparison-of-effects-of-different-doses-dexmedetomidine-on-inhibiting-tracheal-intubation-evoked-haemodynamic-response-in-the-elderly-patients
#10
Guan Zhan-Ying, Wang Chang-Ming, Tang Shuai, Tong Lin-Lin, Han Yu-Feng
BACKGROUND: Dexmedetomidine (DEX) is a selective α2-adrenergic receptor agonist with anxiolytic and analgesic properties. In the present study, we aimed primarily to assess the effects of DEX on sedation, cognitive function and cardiovascular reflex responses before, during and after the tracheal intubation in the elderly patients. MATERIALS AND METHODS: Eighty patients undergoing elective abdominal surgery were randomly assigned to four Groups: Group A(saline, n=20), Group B (0...
September 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26459260/age-dependent-decrease-in-desflurane-concentration-for-maintaining-bispectral-index-below-50
#11
S Kanazawa, Y Oda, C Maeda, R Okutani
BACKGROUND: We examined the hypothesis that the minimum alveolar concentration of desflurane for maintaining bispectral index (BIS) below 50 (MACBIS 50 ) decreases with advance of age. METHODS: Sixty young (20-30 year), middle-aged (31-65 year) and elderly (66-80 year) patients were included (n = 20, each group). Five minutes following the start of continuous intravenous administration of remifentanil at 0.25 μg/kg/min, general anaesthesia was induced with propofol 2 mg/kg and rocuronium 0...
February 2016: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/26446479/effects-of-dexmedetomidine-on-smooth-emergence-from-anaesthesia-in-elderly-patients-undergoing-orthopaedic-surgery
#12
RANDOMIZED CONTROLLED TRIAL
Dong Jun Kim, Sang Hun Kim, Keum Young So, Ki Tae Jung
BACKGROUND: Intraoperative dexmedetomidine may decrease postoperative emergence agitation in elderly patients due to its sedative effect. In this study, we evaluated the effect of adjuvant dexmedetomidine on smooth emergence from anaesthesia after orthopaedic surgery in elderly patients. METHODS: A total 115 patients (ASA I-II, aged over 65 years) were randomly allocated into four groups. Anaesthesia was maintained with either sevoflurane or total intravenous anaesthesia (TIVA) comprising propofol and remifentanil...
October 7, 2015: BMC Anesthesiology
https://www.readbyqxmd.com/read/26413731/pharmacokinetic-and-pharmacodynamic-study-of-dexmedetomidine-in-elderly-patients-during-spinal-anesthesia
#13
Yun Kuang, Ran-Ran Zhang, Qi Pei, Hong-Yi Tan, Cheng-Xian Guo, Jie Huang, Yu-Xia Xiang, Wen Ouyang, Kai-Ming Duan, Sai-Ying Wang, Guo-Ping Yang
OBJECTIVE: The application of dexmedetomidine in patient sedation is generally accepted, though its clinical application is limited because of the lack of information detailing the specific properties among diverse populations of patients. The aim of this study was to compare the pharmacokinetic and pharmacodynamic characteristics of dexmedetomidine between elderly and young patients during spinal anesthesia. METHODS: 34 subjects (elderly group: n = 15; young group: n = 19) with spinal anesthesia were enrolled in the present study following the inclusion/exclusion criteria detailed below...
December 2015: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/26379954/effects-of-dexmedetomidine-on-anesthesia-recovery-period-and-postoperative-cognitive-function-of-patients-after-robot-assisted-laparoscopic-radical-cystectomy
#14
Lingling Ding, Hong Zhang, Weidong Mi, Tao Wang, Yan He, Xu Zhang, Xin Ma, Hongzhao Li
OBJECTIVE: The purpose of the study was to evaluate the neuroprotective effect of dexmedetomidine on anesthesia recovery period and postoperative cognitive function of patients after robot-assisted laparoscopic radical cystectomy and ileal conduit diversion. METHODS: A total of 40 elective patients who would undergo robot-assisted laparoscopic radical cystectomy and ileal conduit diversion. They were randomly divided into two groups in a double-blind manner. After pneumoperitoneum established, all patients adopted 40° trendelenberg position...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26368663/remifentanil-requirement-for-inhibiting-responses-to-tracheal-intubation-and-skin-incision-is-reduced-in-patients-with-parkinson-s-disease-undergoing-deep-brain-stimulator-implantation
#15
Jia-Feng Wang, Xiao-Ping Xu, Xi-Ya Yu, Jin-Bao Li, Xi Wu, Jian-Chun Chen, Xiao-Wu Hu, Xiao-Ming Deng
BACKGROUND: Parkinson's disease (PD) is a common neurodegenerative disease affecting the quality of life in the elderly. We speculated that PD patients might have abnormal pharmacodynamics due to the degenerative neural system, and the present study was performed to investigate the pharmacodynamics of remifentanil in PD patients. MATERIALS AND METHODS: Two arms of patients were recruited, including 31 PD patients undergoing pulse generator placement after deep brain stimulator implantation and 31 pair-controlled patients undergoing intracranial surgery without PD (NPD)...
October 2016: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/26323728/effect-of-low-dose-dexmedetomidine-premedication-on-propofol-consumption-in-geriatric-end-stage-renal-disease-patients
#16
Pinar Ergenoglu, Sule Akin, Cagla Bali, Hatice Evren Eker, Oya Yalcin Cok, Anis Aribogan
BACKGROUND AND OBJECTIVE: Sedation in dialysis dependent end-stage renal disease patients requires caution as a result of performing high doses of sedatives and its complications. Multidrug sedation regimens might be superior and advantage on lesser drug consumption and by the way adverse events which occur easily in end-stage renal disease patients. We evaluated the effects of dexmedetomidine premedication on propofol consumption, sedation levels with Observer's Assessment of Alertness and Sedation scores and the bispectral index and the hemodynamic changes, potential side effects in geriatric patients with end-stage renal disease who underwent hip fracture surgery under spinal anesthesia...
September 2015: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/26301406/propofol-sedation-with-a-target-controlled-infusion-pump-and-bispectral-index-monitoring-system-in-elderly-patients-during-a-complex-upper-endoscopy-procedure
#17
Tatsuhiro Gotoda, Hiroyuki Okada, Keisuke Hori, Yoshiro Kawahara, Masaya Iwamuro, Makoto Abe, Yoshiyasu Kono, Kou Miura, Hiromitsu Kanzaki, Masahide Kita, Seiji Kawano, Kazuhide Yamamoto
BACKGROUND AND AIMS: Although the usefulness of propofol sedation during endoscopic submucosal dissection (ESD) for gastric neoplasms was reported previously, information is limited on its use in elderly patients. We investigated the safety and efficacy of propofol sedation with a target-controlled infusion (TCI) pump and bispectral index (BIS) monitoring system (TCI/BIS system) in elderly patients during gastric ESD. METHODS: Included were 413 consecutive gastric ESD procedures involving 455 lesions (379 patients) performed in patients under propofol sedation with a TCI/BIS system between October 2009 and September 2013...
April 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/26296981/-effect-of-low-dose-dexmedetomidine-premedication-on-propofol-consumption-in-geriatric-end-stage-renal-disease-patients
#18
Pinar Ergenoglu, Sule Akin, Cagla Bali, Hatice Evren Eker, Oya Yalcin Cok, Anis Aribogan
BACKGROUND AND OBJECTIVE: Sedation in dialysis dependent end-stage renal disease patients requires caution as a result of performing high doses of sedatives and its complications. Multidrug sedation regimens might be superior and advantage on lesser drug consumption and by the way adverse events which occur easily in end-stage renal disease patients. We evaluated the effects of dexmedetomidine premedication on propofol consumption, sedation levels with Observer's Assessment of Alertness and Sedation scores and the bispectral index and the hemodynamic changes, potential side effects in geriatric patients with end-stage renal disease who underwent hip fracture surgery under spinal anesthesia...
September 2015: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/26228208/comparison-of-c%C3%A2-%C3%A2-for-propofol-remifentanil-target-controlled-infusion-and-bispectral-index-at-loss-of-consciousness-and-response-to-painful-stimulus-in-elderly-and-young-patients
#19
Ning Yang, Ming-Zhang Zuo, Yun Yue, Yun Wang, Yu Shi, Xue-Na Zhang
BACKGROUND: In this prospective randomized study, we compared the predicted blood and effect-site C 50 for propofol and remifentanil target-controlled infusion (TCI) and the bispectral index (BIS) values at loss of consciousness (LOC) and response to a standard noxious painful stimulus (LOS) in elderly and young patients, respectively. We hypothesized that the elderly patients will require lower target concentration of both propofol and remifentanil at above two clinical end-points. METHODS: There were 80 American Society of Anesthesiologists (ASA) physical status I-II unpremedicated patients enrolled in this study, they were divided into elderly group (age ≥65 years, n = 40) and young group (aged 18-64 years, n = 40)...
August 5, 2015: Chinese Medical Journal
https://www.readbyqxmd.com/read/26086293/falsely-reduced-bispectral-index-during-light-anaesthesia-in-the-elderly
#20
LETTER
Kazuko Hayashi, Teiji Sawa
No abstract text is available yet for this article.
February 2016: European Journal of Anaesthesiology
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