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https://www.readbyqxmd.com/read/28428134/use-of-physiological-biomarkers-in-diagnosis-along-with-field-trials-of-different-trypanisidal-drugs-in-camels-of-cholistan-desert
#1
Aneela Zameer Durrani, Zubair Bashir, Khalid Mehmood, Muhammad Avais, Haroon Akbar, Waqas Ahmad, Muhammad Azeem
The point prevalence of trypanosomiasis with different physiological biomarkers along with evaluation of the most responsive trypanosidal drug against trypanosomiasis under field conditions was studied. For this purpose a total of 300 free range camels were selected at different grazing and watering point in Cholistan desert. The study population of camels included 150 clinically suspected camels for trypanosomiasis and 150 healthy camels with normal temperature, pulse and respiration. For therapeutic trials 36 positively diagnosed animals were randomly divided into three experimental groups for therapeutic trials...
April 17, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28428133/epidemiological-study-of-common-diseases-and-their-risk-factors-in-camels-in-south-punjab-pakistan
#2
Aneela Zameer Durrani, Zubair Bashir, Imran Rasheed, Noor-Ul-Ain Sarwar
Bacteriological study of mastitis along with common blood protozoan diseases were studied in dromedary camels in Cholistan, Dera Ismail Khan and Rahim Yar Khan districts in South Punjab, Pakistan. For this purpose 300 camels were sampled randomly at different common grazing and watering point. For study of blood parasites clinically suspected and apparently healthy camels, 150 each, were sampled. An overall prevalence of 15%and 5% was recorded for trypanosomiasis and Anaplasmosis respectively. Trypanosoma evansi was identified with 280 bp product on polymerase chain reaction test...
April 17, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28425927/hepatitis-e-virus-genotypes-and-evolution-emergence-of-camel-hepatitis-e-variants
#3
REVIEW
Siddharth Sridhar, Jade L L Teng, Tsz-Ho Chiu, Susanna K P Lau, Patrick C Y Woo
Hepatitis E virus (HEV) is a major cause of viral hepatitis globally. Zoonotic HEV is an important cause of chronic hepatitis in immunocompromised patients. The rapid identification of novel HEV variants and accumulating sequence information has prompted significant changes in taxonomy of the family Hepeviridae. This family includes two genera: Orthohepevirus, which infects terrestrial vertebrates, and Piscihepevirus, which infects fish. Within Orthohepevirus, there are four species, A-D, with widely differing host range...
April 20, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28421799/antihypertensive-effect-of-fermented-skim-camel-camelus-dromedarius-milk-on-spontaneously-hypertensive-rats
#4
Mohammed A Yahya, Omar A Alhaj, Abdullrahman S Al-Khalifah
BACKGROUND: Hypertension is one of the most common diseases in worldwide, thus prevention of hypertension is important in reducing the risks of cardiovascular disease. Milk contains bioactive peptides released during milk fermentation which lead to exhibit angiotensin I converting enzyme (ACE) inhibitory. OBJECTIVE: The aim of this study was to investigate the antihypertensive effect of fermented skim camel milk on rats and compared with unfermented skim camel milk as control...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28421029/a-historical-view-of-motion-sickness-a-plague-at-sea-and-on-land-also-with-military-impact
#5
Doreen Huppert, Judy Benson, Thomas Brandt
Seasickness and its triggers, symptoms, and preventive measures were well known in antiquity. This chapter is based on an analysis of descriptions of motion sickness, in particular seasickness, in ancient Greek, Roman, and Chinese literature. A systematic search was made from the Greek period beginning with Homer in 800 BC to the late Roman period and ending with Aetios Amidenos in 600 AD, as well as in the Chinese medical classics dating from around 300 AD. Major aspects are the following: body movements caused by waves were identified in all cultures as the critical stimuli...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28413471/influence-of-camel-milk-on-the-hepatitis-c-virus-burden-of-infected-patients
#6
Esmail Mohamad El-Fakharany, Nawal Abd El-Baky, Mustafa Hassan Linjawi, Abdullah Abdelhafiz Aljaddawi, Tahya Hussein Saleem, Ahmed Yassine Nassar, Ashraf Osman, Elrashdy Moustafa Redwan
Hepatitis C virus (HCV) infection represents a world health problem and no protective vaccine or effective drug currently exists. For economic reasons, many patients use traditional medicines to control the infection. In Egypt, camel milk is one of the traditional medicines widely consumed by patients infected with HCV. The present study aimed to evaluate the efficacy of camel milk in the treatment of patients infected with HCV. Whole camel milk from a local farm was administered to patients for 4 months (250 ml/day/patient)...
April 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28413155/effects-of-natural-environment-on-reproductive-histo-morphometric-dynamics-of-female-dromedary-camel
#7
Hafiz Muhammad Ali, Anas Sarwar Qureshi, Riaz Hussain, Giorgia Urbinati, Mohammad Zahid Mustafa, Farah Ali, Abdul Manan, Liliane Massaad-Massade
Camel shows a seasonal breeding pattern with enhanced reproductive activity during the period of low climatic temperature, high rainfall and better food conditions. Therefore, the study was conducted to explore the underlying seasonal effects on histological dimensions of reproductive tract in adult female one-humped camel (Camelus dromedarius) kept in the natural environment of Pakistan. A total 25 reproductive tracts were collected during spring, summer, autumn and winter seasons and were analysed for histo-morphometric parameters during different environmental conditions...
March 29, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28412285/middle-east-respiratory-syndrome-coronavirus-vaccines-current-status-and-novel-approaches
#8
REVIEW
Nisreen Ma Okba, V Stalin Raj, Bart L Haagmans
Middle East respiratory syndrome coronavirus (MERS-CoV) is a cause of severe respiratory infection in humans, specifically the elderly and people with comorbidities. The re-emergence of lethal coronaviruses calls for international collaboration to produce coronavirus vaccines, which are still lacking to date. Ongoing efforts to develop MERS-CoV vaccines should consider the different target populations (dromedary camels and humans) and the correlates of protection. Extending on our current knowledge of MERS, vaccination of dromedary camels to induce mucosal immunity could be a promising approach to diminish MERS-CoV transmission to humans...
April 13, 2017: Current Opinion in Virology
https://www.readbyqxmd.com/read/28403897/trypanosoma-vivax-is-the-second-leading-cause-of-camel-trypanosomosis-in-sudan-after-trypanosoma-evansi
#9
Ehab Mossaad, Bashir Salim, Keisuke Suganuma, Peter Musinguzi, Mohammed A Hassan, E A Elamin, G E Mohammed, Amel O Bakhiet, Xuenan Xuan, Rawan A Satti, Noboru Inoue
BACKGROUND: This study was conducted in response to recurring reports from eastern Sudan of camel trypanosomosis that can no longer be treated by currently available trypanocidal drugs. One hundred and eighty-nine blood samples were obtained from camels in different herds and local markets in the western part of Sudan, and a cross-sectional study was carried out between December 2015 and February 2016 to identify the causative agents and possible circulating genotypes. RESULTS: The prevalence of trypanosomes detected using the conventional parasitological techniques of Giemsa-stained blood smears, wet blood smears and the microhematocrit centrifugation technique (MHCT) was 7% (13/189), 11% (21/189) and 19% (36/189), respectively...
April 13, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28402847/igf1-shapes-macrophage-activation-in-response-to-immunometabolic-challenge
#10
Olga Spadaro, Christina D Camell, Lidia Bosurgi, Kim Y Nguyen, Yun-Hee Youm, Carla V Rothlin, Vishwa Deep Dixit
In concert with their phagocytic activity, macrophages are thought to regulate the host immunometabolic responses primarily via their ability to produce specific cytokines and metabolites. Here, we show that IL-4-differentiated, M2-like macrophages secrete IGF1, a hormone previously thought to be exclusively produced from liver. Ablation of IGF1 receptors from myeloid cells reduced phagocytosis, increased macrophages in adipose tissue, elevated adiposity, lowered energy expenditure, and led to insulin resistance in mice fed a high-fat diet...
April 11, 2017: Cell Reports
https://www.readbyqxmd.com/read/28402703/molecular-detection-of-francisella-spp-among-ticks-attached-to-camels-in-egypt
#11
Nahed H Ghoneim, Khaled A Abdel-Moein, Hala M Zaher
This study was conducted to investigate the possible role of camels and attached ticks in the epidemiology of Francisella spp. including Francisella tularensis. For this purpose, a total of 319 ticks (248 Hyalomma dromedarii and 71 Amblyomma spp.) as well as 100 blood and 50 fecal samples collected from camels were screened for the presence of Francisella spp. by PCR through amplification of Francisella 16S rRNA gene. Positive samples were then tested for F. tularensis by PCR. In addition, serum samples from 75 camel abattoir workers were examined for the presence of IgG antibodies against F...
April 12, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28400990/classifications-of-multispectral-colorectal-cancer-tissues-using-convolution-neural-network
#12
Hawraa Haj-Hassan, Ahmad Chaddad, Youssef Harkouss, Christian Desrosiers, Matthew Toews, Camel Tanougast
BACKGROUND: Colorectal cancer (CRC) is the third most common cancer among men and women. Its diagnosis in early stages, typically done through the analysis of colon biopsy images, can greatly improve the chances of a successful treatment. This paper proposes to use convolution neural networks (CNNs) to predict three tissue types related to the progression of CRC: benign hyperplasia (BH), intraepithelial neoplasia (IN), and carcinoma (Ca). METHODS: Multispectral biopsy images of thirty CRC patients were retrospectively analyzed...
2017: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/28397518/identification-and-phylogenetic-analysis-of-contagious-ecthyma-virus-from-camels-i-camelus-dromedarius-i-in-iran
#13
Ahmad Oryan, Mahboobe Mosadeghhesari, Saeed Zibaee, Ali Mohammadi
Contagious ecthyma is a highly contagious disease affecting domestic and wild ruminants such as sheep, goats and camels. The identification and characterisation of a parapoxvirus (PPV) infecting camels is described here. The virus was detected in dromedary camels (Camelus dromedarius) from Kerman and Shiraz in Iran. PPV-specific amplification by polymerase chain reaction (PCR) further confirmed that the disease was associated with PPV infection. Phylogenetic analysis of ORF011 (B2L) gene sequences showed 99...
March 24, 2017: Onderstepoort Journal of Veterinary Research
https://www.readbyqxmd.com/read/28394889/seroprevalence-of-q-fever-among-human-and-animal-in-iran-a-systematic-review-and-meta-analysis
#14
Ashraf Mohabbati Mobarez, Fahimeh Bagheri Amiri, Saber Esmaeili
BACKGROUND: Q fever is a main zoonotic disease around the world. The aim of this meta-analysis was to estimate the overall seroprevalence of Coxiella burnetii among human and animal population in Iran. METHODS: Major national and international databases were searched from 2005 up to August 2016. We extracted the prevalence of Q fever antibodies (IgG) as the main primary outcome. We reported the prevalence of the seropositivity as point and 95% confidence intervals...
April 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28393862/characterization-of-chiral-amino-acids-from-different-milk-origins-using-ultra-performance-liquid-chromatography-coupled-to-ion-mobility-mass-spectrometry
#15
He Tian, Nan Zheng, Songli Li, Yangdong Zhang, Shengguo Zhao, Fang Wen, Jiaqi Wang
Milk contains free amino acids (AAs) that play essential roles in maintaining the growth and health of infants, and D-AA isomers are increasingly being recognized as important signalling molecules. However, there are no studies of the different characteristics of chiral AA (C-AA) from different milk origins. Here, UPLC coupled to ion-mobility high-resolution MS (IM-HRMS) was employed to characterize 18 pairs of C-AAs in human, cow, yak, buffalo, goat, and camel milk. The results proved that milk origins can be differentiated based on the D- to L- AA ratio-based projection scores by principal component analysis...
April 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28387845/identification-of-risk-factors-for-primary-mers-cov-infection-in-camel-workers-in-qatar-2013-2014-a-case-control-study
#16
Reina S Sikkema, Elmoubasher A B A Farag, Sayed Himatt, Adel K Ibrahim, Hamad Al-Romaihi, Salih A Al-Marri, Mohamed Al-Thani, Ahmed M H El-Sayed, Mohammed Al-Hajri, Bart L Haagmans, Marion P G Koopmans, Chantal B E M Reusken
The transmission routes and risk factors for zoonotic MERS-CoV infections are still unknown. We used the WHO questionnaire for MERS-CoV case-control studies to assess risk factors for human MERS-CoV seropositivity at a farm complex in Qatar. Nine camel workers with MERS-CoV antibodies and 43 workers without antibodies were included. Some camel-related activities may pose a higher risk of MERS-CoV infection, as well as cross-border movements of camels, poor hand hygiene and overnight hospital stays with respiratory complaints ...
April 6, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28382915/risk-factors-for-mers-coronavirus-infection-in-dromedary-camels-in-burkina-faso-ethiopia-and-morocco-2015
#17
Eve Miguel, Véronique Chevalier, Gelagay Ayelet, Med Nadir Ben Bencheikh, Hiver Boussini, Daniel Kw Chu, Ikhlass El Berbri, Ouaffa Fassi-Fihri, Bernard Faye, Getnet Fekadu, Vladimir Grosbois, Bryan Cy Ng, Ranawaka Apm Perera, T Y So, Amadou Traore, François Roger, Malik Peiris
Understanding Middle East respiratory syndrome coronavirus (MERS-CoV) transmission in dromedary camels is important, as they consitute a source of zoonotic infection to humans. To identify risk factors for MERS-CoV infection in camels bred in diverse conditions in Burkina Faso, Ethiopia and Morocco, blood samples and nasal swabs were sampled in February-March 2015. A relatively high MERS-CoV RNA rate was detected in Ethiopia (up to 15.7%; 95% confidence interval (CI): 8.2-28.0), followed by Burkina Faso (up to 12...
March 30, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28381251/seroprevalence-of-rift-valley-fever-virus-in-livestock-during-inter-epidemic-period-in-egypt-2014-15
#18
Claudia Mroz, Mayada Gwida, Maged El-Ashker, Mohamed El-Diasty, Mohamed El-Beskawy, Ute Ziegler, Martin Eiden, Martin H Groschup
BACKGROUND: Rift Valley fever virus (RVFV) caused several outbreaks throughout the African continent and the Arabian Peninsula posing significant threat to human and animal health. In Egypt the first and most important Rift Valley fever epidemic occurred during 1977/78 with a multitude of infected humans and huge economic losses in livestock. After this major outbreak, RVF epidemics re-occurred in irregular intervals between 1993 and 2003. Seroprevalence of anti-RVFV antibodies in livestock during inter-epidemic periods can be used for supporting the evaluation of the present risk exposure for animal and public health...
April 5, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28372475/in-vivo-antitumour-potential-of-camel-s-milk-against-hepatocellular-carcinoma-in-rats-and-its-improvement-of-cisplatin-renal-side-effects
#19
Hala M F El Miniawy, Kawkab A Ahmed, Sameeh A Mansour, Marwa M Salah Khattab
CONTEXT: Camel milk (CM) is recommended for liver disease patients in Egypt for a strong belief that it has a curative effect. OBJECTIVE: The effect of consumption of CM with or without chemotherapeutic drug cisplatin was evaluated on induced hepatocarcinogenesis in rats. MATERIALS AND METHODS: Wistar male rats (56) were divided into eight groups (7 rats each). Group I was control. Hepatocarcinogenesis was initiated by a single dose of intraperitoneal injection of diethylnitrosamine (DENA) (200 mg/kg BW) and promoted by phenobarbitone (500 ppm) in drinking water in groups V, VI, VII and VIII...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28367365/daily-rhythms-of-behavioral-and-hormonal-patterns-in-male-dromedary-camels-housed-in-boxes
#20
Lydiane Aubè, Meriem Fatnassi, Davide Monaco, Touhami Khorchani, Giovanni Michele Lacalandra, Mohamed Hammadi, Barbara Padalino
BACKGROUND: Daily rhythmicity has been observed for a number of hormonal and behavioral variables in mammals. It can be entrained by several external factors, such as light-dark cycle and scheduled feeding. In dromedary camels, daily rhythmicity has been documented only for melatonin secretion and body temperature. In this study, the daily rhythmicity of behavioral repertoire, cortisol and testosterone levels was investigated in captive male camels. METHODS: Six clinically healthy male dromedary camels (Camelus dromedarius) were used...
2017: PeerJ
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