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https://www.readbyqxmd.com/read/28937737/hollow-pd-ag-composite-nanowires-for-fast-responding-and-transparent-hydrogen-sensors
#1
Ji-Soo Jang, Shaopeng Qiao, Seon-Jin Choi, Gaurav Jha, Alana F Ogata, Won-Tae Koo, Dong-Ha Kim, Il-Doo Kim, Reginald M Penner
Pd based alloy materials with hollow nanostructures are ideal hydrogen (H2) sensor building blocks because of the ultra-high surface area afforded by this architecture. In this work, for the first time, we report a simple fabrication process for preparing hollow Pd-Ag alloy nanowires (Pd@Ag HNWs) by using the electrodeposition of lithographically patterned silver nanowires and followed galvanic replacement reaction (GRR) to form palladium. By controlling the GRR time of aligned Ag NWs within an aqueous Pd2+-containing solution, the compositional transition and morphological evolution from Ag NWs to Pd@Ag HNWs simultaneously occurred, and the relative atomic ratio between Pt and Ag was controlled...
September 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28933815/magnetotactic-bacteria-powered-biohybrids-target-e-coli-biofilms
#2
Morgan M Stanton, Byung-Wook Park, Diana Vilela, Klaas Bente, Damien Faivre, Metin Sitti, Samuel Sanchez
Biofilm colonies are typically resistant to general antibiotic treatment and require targeted methods for their removal. One of these methods include the use of nanoparticles as carriers for antibiotic delivery, where they randomly circulate in fluid until they make contact with the infected areas. However, the required proximity of the particles to the biofilm results in only moderate efficacy. We demonstrate here that the non-pathogenic magnetotactic bacteria, Magnetosopirrillum gryphiswalense (MSR-1), can be integrated with drug-loaded mesoporous silica microtubes (MSMs) to build controllable microswimmers (biohybrids) capable of antibiotic delivery to target an infectious biofilm...
September 21, 2017: ACS Nano
https://www.readbyqxmd.com/read/28926255/infrared-spectroscopic-and-theoretical-studies-on-the-omf2-and-omf-m-cr-mo-w-molecules-in-solid-argon
#3
Rui Wei, Qingnuan Li, Yu Gong, Lester Andrews, Zongtang Fang, Kanchana Sahan Thanthiriwatte, Monica Vasiliu, David A Dixon
Group 6 metal oxide fluoride molecules in the form of OMF2 and OMF (M=Cr, Mo, W) have been prepared via the reactions of laser-ablated metal atoms and OF2 in excess argon. Product identifications were carried out by using infrared spectroscopy, 18OF2 sample and electronic structure calculations. Reactions of group 6 metal atoms and OF2 resulted in the formation of ternary OCrF2, OMoF2 and OWF2 molecules with C2v symmetry in which the tetravalent metal center is coordinated by one oxygen and two fluorine atoms...
September 19, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28925212/fra-introduksjonsbok-til-metodebok
#4
Bente Prytz Mjølstad
No abstract text is available yet for this article.
September 19, 2017: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/28924674/spine-posture-influences-tactile-perceptual-sensitivity-of-the-trunk-dorsum
#5
Shawn M Beaudette, Simone G V S Smith, Leah R Bent, Stephen H M Brown
The purpose of the current work was to quantify the influence of posture-mediated skin deformation on trunk dorsum tactile perceptual sensitivity. Twelve young and healthy individuals were assessed while adopting three different spine postures (extension, neutral and flexion). Tactile sensitivity threshold tests (T10 and L4 vertebral levels) included measures of touch sensitivity, spatial acuity and stretch sensitivity. The results demonstrate that tactile sensitivity can differ due to changes in body posture...
September 18, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28919907/heterotrimeric-g-protein-regulated-ca-2-influx-and-pin2-asymmetric-distribution-are-involved-in-arabidopsis-thaliana-roots-avoidance-response-to-extracellular-atp
#6
Ruojia Zhu, Xiaoxia Dong, Weiwei Hao, Wei Gao, Wenzhu Zhang, Shuyan Xia, Ting Liu, Zhonglin Shang
Extracellular ATP (eATP) has been reported to be involved in plant growth as a primary messenger in the apoplast. Here, roots of Arabidopsis thaliana seedlings growing in jointed medium bent upon contact with ATP-containing medium to keep away from eATP, showing a marked avoidance response. Roots responded similarly to ADP and bz-ATP but did not respond to AMP and GTP. The eATP avoidance response was reduced in loss-of-function mutants of heterotrimeric G protein α subunit (Gα) (gpa1-1 and gpa1-2) and enhanced in Gα-over-expression (OE) lines (wGα and cGα)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28919610/open-door-laminoplasty-for-multilevel-cervical-spondylotic-myelopathy-and-ossification-of-the-posterior-longitudinal-ligament-opll-using-titanium-reconstruction-miniplate-and-screws
#7
M K Ahsan, M A Awwal, S I Khan, N Zaman, M H Haque, Z Zahangiri
To review outcome of 25 patients who underwent open-door cervical laminoplasty for multilevel cervical spondylotic myelopathy (MCSM) and ossification of the posterior longitudinal ligament (OPLL) using titanium reconstruction miniplate and screws. Records of 18 men and 7 women aged 35 to 78 (mean, 62.6) years were reviewed retrospectively from October 2009 and October 2014 at Bangabandhu Sheikh Mujib Medical University (BSMMU) and in our private settings, Dhaka, Bangladesh. Four patients had 5 levels (C3-C7), 21 patients had 4 levels (C3-C6) decompression and 3 patients (12%) performed foraminotomies...
July 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28919542/ageing-reduces-light-touch-and-vibrotactile-sensitivity-on-the-anterior-lower-leg-and-foot-dorsum
#8
R L Mildren, M C Yip, C R Lowery, C Harpur, S H M Brown, L R Bent
Cutaneous mechanoreceptors in the anterior lower leg and foot dorsum provide important information about contact with objects and movement at the knee and ankle. This cutaneous feedback contributes to static and dynamic balance control. We conducted experiment 1 to determine the effects of ageing on anterior lower leg cutaneous feedback. We measured light touch (monofilament) perceptual thresholds (MPT) at seven skin sites across the anterior lower leg and foot dorsum in 12 young (5 male, aged 21-28) and 13 older adults (8 male, aged 73-92)...
September 15, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28919340/design-and-synthesis-of-pregnenolone-2-cyanoacryloyl-conjugates-with-dual-nf-%C3%AE%C2%BAb-inhibitory-and-anti-proliferative-activities
#9
Jia-Li Song, Juan Zhang, Chang-Liang Liu, Chao Liu, Kong-Kai Zhu, Fei-Fei Yang, Xi-Gong Liu, João Paulo Figueiró Longo, Luis Alexandre Muehlmann, Ricardo Bentes Azevedo, Yu-Ying Zhang, Yue-Wei Guo, Cheng-Shi Jiang, Hua Zhang
Twenty-five novel pregnenolone/2-cyanoacryloyl conjugates (6-30) were designed and prepared, with the aim of developing novel anticancer drugs with dual NF-κB inhibitory and anti-proliferative activities. Compounds 22 and 27-30 showed inhibition against TNF-α-induced NF-κB activation in luciferase assay, which was confirmed by Western blotting. Among them, compound 30 showed potent NF-κB inhibitory activity (IC50=2.5μM) and anti-proliferative against MCF-7, A549, H157, and HL-60 cell lines (IC50=6.5-36...
September 8, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28915910/colonization-of-the-bovine-uterus-by-candida-kefyr
#10
Cecilia Christensen Karstrup, Bent Aalbæk, Kirstine Klitgaard, Tim Kåre Jensen, Hanne Gervi Pedersen, Jørgen Steen Agerholm
BACKGROUND: While fungal infections of the bovine uterus are well-known diseases in pregnant cattle, very limited knowledge exists on the presence and significance of fungi in the uterus of non-pregnant cows. Presence of fungi in the uterine lumen of postpartum (pp) cows has been reported, but little attention has been paid to this as most studies of the bovine pp uterus have focused on bacteria. CASE PRESENTATION: Microscopy of uterine lavage cytology slides of three cows from one herd revealed the presence of numerous yeast-like organisms, which were located either free in the fluid or within macrophages...
September 16, 2017: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/28915377/midwives-%C3%A2-experiences-of-caring-for-pregnant-women-admitted-to-ebola-centres-in-sierra-leone
#11
REVIEW
Elin Erland, Bente Dahl
OBJECTIVE: to explore and describe midwives' experiences of caring for pregnant women admitted to Ebola centres in Sierra Leone. DESIGN: a qualitative interview study with an exploratory and descriptive approach. SETTING: individual semi-structured interviews with midwives who provided care for pregnant woman in eight different Ebola centres in Sierra Leone during the Ebola outbreak in 2014-16. PARTICIPANTS: 11 midwives, Sierra Leoneans and expatriates, who worked for three different humanitarian organisations in Sierra Leone during the Ebola outbreak in 2014-2016...
September 1, 2017: Midwifery
https://www.readbyqxmd.com/read/28914463/burrowing-with-a-kinetic-snout-in-a-snake-elapidae-aspidelaps-scutatus
#12
Alexandra Deufel
Of the few elongate, fossorial vertebrates that have been examined for their burrowing mechanics, all were found to use an akinetic, reinforced skull to push into the soil, powered mostly by trunk muscles. Reinforced skulls were considered essential for head-first burrowing. In contrast, I found that the skull of the fossorial shield-nosed cobra (Aspidelaps scutatus) is not reinforced and retains the kinetic potential typical of many non-fossorial snakes. Aspidelaps scutatus burrows using a greatly enlarged rostral scale that is attached to a kinetic snout that is independently mobile with respect to the rest of the skull...
September 15, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28912355/diverse-p53-dna-binding-modes-expand-the-repertoire-of-p53-response-elements
#13
Pratik Vyas, Itai Beno, Zhiqun Xi, Yan Stein, Dmitrij Golovenko, Naama Kessler, Varda Rotter, Zippora Shakked, Tali E Haran
The tumor suppressor protein p53 acts as a transcription factor, binding sequence-specifically to defined DNA sites, thereby activating the expression of genes leading to diverse cellular outcomes. Canonical p53 response elements (REs) are made of two decameric half-sites separated by a variable number of base pairs (spacers). Fifty percent of all validated p53 REs contain spacers between 1 and 18 bp; however, their functional significance is unclear at present. Here, we show that p53 forms two different tetrameric complexes with consensus or natural REs, both with long spacers: a fully specific complex where two p53 dimers bind to two specific half-sites, and a hemispecific complex where one dimer binds to a specific half-site and the second binds to an adjacent spacer sequence...
September 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28902841/cgas-senses-long-and-hmgb-tfam-bound-u-turn-dna-by-forming-protein-dna-ladders
#14
Liudmila Andreeva, Björn Hiller, Dirk Kostrewa, Charlotte Lässig, Carina C de Oliveira Mann, David Jan Drexler, Andreas Maiser, Moritz Gaidt, Heinrich Leonhardt, Veit Hornung, Karl-Peter Hopfner
Cytosolic DNA arising from intracellular pathogens triggers a powerful innate immune response. It is sensed by cyclic GMP-AMP synthase (cGAS), which elicits the production of type I interferons by generating the second messenger 2'3'-cyclic-GMP-AMP (cGAMP). Endogenous nuclear or mitochondrial DNA can also be sensed by cGAS under certain conditions, resulting in sterile inflammation. The cGAS dimer binds two DNA ligands shorter than 20 base pairs side-by-side, but 20-base-pair DNA fails to activate cGAS in vivo and is a poor activator in vitro...
September 13, 2017: Nature
https://www.readbyqxmd.com/read/28902116/adding-whole-body-vibration-to-preconditioning-squat-exercise-increases-cycling-sprint-performance
#15
Sébastien Duc, Bent R Rønnestad, William Bertucci
This study investigated the effect of performing a preconditioning exercise with or without whole-body vibration (WBV) on a subsequent cycling sprint performance. Fourteen trained subjects performed two separate test sessions in randomized order. After a warm-up, the preconditioning exercise (body-loaded half squats) was applied: 30-seconds of half-squats with WBV (40 Hz, 2 mm) or 30-seconds of half-squats without WBV with a 10-second all-out sprint performed after one minute. Surface electromyography (EMG) was measured from the vastus medialis, vastus lateralis and gastrocnemius medialis during the sprints...
September 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28900636/examination-of-molecular-packing-in-orthogonal-smectic-liquid-crystal-phases-a-guide-for-molecular-design-of-functional-smectic-phases
#16
Yasuhisa Yamamura, Takahito Murakoshi, Mafumi Hishida, Kazuya Saito
The reported layer spacings (dsmectic) of six homologues of mesogens exhibiting orthogonal smectic phases (SmE, SmB, and SmA phases) are reexamined. The slopes of the linear dependences on chain length (n, the number of carbon atoms in the hydrocarbon chain) are clearly categorized into two groups: 1.9 Å (CH2)(-1) and 1.4 Å (CH2)(-1). It is clarified that in the former the molecules take a rod-like form (rod-form; category-I), whereas in the latter the molecules are bent around the connection between the core and chain moieties (bent-form; category-II)...
September 13, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28900466/can-an-inadequate-cervical-cytology-sample-in-thinprep-be-converted-to-a-satisfactory-sample-by-processing-it-with-a-surepath-preparation
#17
Sveinung Wergeland Sørbye, Mette Kristin Pedersen, Bente Ekeberg, Merete E Johansen Williams, Torill Sauer, Ying Chen
BACKGROUND: The Norwegian Cervical Cancer Screening Program recommends screening every 3 years for women between 25 and 69 years of age. There is a large difference in the percentage of unsatisfactory samples between laboratories that use different brands of liquid-based cytology. We wished to examine if inadequate ThinPrep samples could be satisfactory by processing them with the SurePath protocol. MATERIALS AND METHODS: A total of 187 inadequate ThinPrep specimens from the Department of Clinical Pathology at University Hospital of North Norway were sent to Akershus University Hospital for conversion to SurePath medium...
2017: CytoJournal
https://www.readbyqxmd.com/read/28899417/serotonin-augmentation-therapy-by-escitalopram-has-minimal-effects-on-amyloid-%C3%AE-levels-in-early-stage-alzheimer-s-like-disease-in-mice
#18
Christian Ulrich von Linstow, Jonas Waider, Manuela Grebing, Athanasios Metaxas, Klaus Peter Lesch, Bente Finsen
BACKGROUND: Dysfunction of the serotonergic (5-HTergic) system has been implicated in the cognitive and behavioural symptoms of Alzheimer's disease (AD). Accumulation of toxic amyloid-β (Aβ) species is a hallmark of AD and an instigator of pathology. Serotonin (5-HT) augmentation therapy by treatment with selective serotonin reuptake inhibitors (SSRIs) in patients with AD has had mixed success in improving cognitive function, whereas SSRI administration to mice with AD-like disease has been shown to reduce Aβ pathology...
September 12, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28890449/history-morals-and-medicine
#19
Jonathan D Moreno
This essay provides a rational reconstruction of the author's genetically inscribed inclination to do normative ethics with an historical bent and offers some reflections on the value of historical thinking for bioethics.
2017: Perspectives in Biology and Medicine
https://www.readbyqxmd.com/read/28887941/the-charged-particle-radiation-environment-on-mars-measured-by-msl-rad-from-november-15-2015-to-january-15-2016
#20
Bent Ehresmann, Cary J Zeitlin, Donald M Hassler, Daniel Matthiä, Jingnan Guo, Robert F Wimmer-Schweingruber, Jan K Appel, David E Brinza, Scot C R Rafkin, Stephan I Böttcher, Sönke Burmeister, Henning Lohf, Cesar Martin, Eckart Böhm, Günther Reitz
The Radiation Assessment Detector (RAD) on board the Mars Science Laboratory (MSL) Curiosity rover has been measuring the radiation environment in Gale crater on Mars since August, 2012. These first in-situ measurements provide an important data set for assessing the radiation-associated health risks for future manned missions to Mars. Mainly, the radiation field on the Martian surface stems from Galactic Cosmic Rays (GCRs) and secondary particles created by the GCRs' interactions with the Martian atmosphere and soil...
August 2017: Life Sciences in Space Research
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