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https://www.readbyqxmd.com/read/28324817/developmental-toxicity-and-induction-of-vitellogenin-in-embryo-larval-stages-of-zebrafish-danio-rerio-exposed-to-methyl-paraben
#1
Vrinda Yatin Dambal, Karthikeyan Ponnien Selvan, Christy Lite, S Barathi, Winkins Santosh
MethylParaben (MP), a methyl ester of p-hydroxybenzoic acid, is used as an anti-microbial preservative in foods, drugs and cosmetics for decades. It enters the aquatic environment, and can have toxic effects on aquatic organisms. Little is known on the developmental toxicity of MP exposure to zebrafish during early life stages. In this study, the developmental effects of MP were evaluated in embryo-larval zebrafish (at concentrations ranging from 100μM, 200μM, 400µM, 800μM and 1000μM for 96h post fertilization (hpf)...
March 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28320082/rosmarinic-acid-plays-a-protective-role-in-the-embryogenesis-of-zebrafish-exposed-to-food-colours-through-its-influence-on-aurora-kinase-a-level
#2
Y Swarnalatha, I S Jerrine Joseph, Tippabathani Jayakrishna
OBJECTIVE: To evaluate the protective nature of the rosmarinic acid from Sphaeranthus amaranthoides during zebra fish embryogenesis. METHODS: Rosmarinic acid was isolated from the S. amaranthoides. An accurate, sensitive and simple LC-MS analysis was performed to determine the rosmarinic acid from S. amaranthoides. In the present study, zebrafish embryos were exposed to crimson red and sunset yellow at a concentration of 0.1 and 0.5mg/l and the effect of these food colours on the levels of aurora kinase A was studied individually...
March 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28319900/bipolar-electrochemiluminescence-on-thread-a-new-class-of-electroanalytical-sensors
#3
Rui Liu, Cuiling Liu, Huijie Li, Min Liu, Dan Wang, Chunsun Zhang
This paper introduces a new and simple concept for fabricating low-cost, easy-to-use capillary microchannel (CMC) assisted thread-based microfluidic analytical devices (CMCA-μTADs) for bipolar electrochemiluminescence (BP-ECL) application. The thread with patterns of carbon screen-printed electrodes and bare thread zones (BTZs) is embedded into a CMC. Such CMCA-μTADs can produce a strong and stable BP-ECL signal, and have an extremely low cost ($0.01 per device). Interestingly, the CMCA-μTADs are ultraflexible, and can be bent with a 135° bending angle at the BTZ or with a 150° bending angle at the middle of bipolar electrode (BPE), with no loss of analytical performance...
March 7, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28318927/classical-versus-custom-orbital-wall-reconstruction-selected-factors-regarding-surgery-and-hospitalization
#4
Rafał Zieliński, Marta Malińska, Marcin Kozakiewicz
PURPOSE: Nowadays, in orbital wall reconstruction, maxillofacial surgeons have the possibility to treat patients in modern ways such as with individual implants. Nevertheless, conventional treatment including standard titanium mesh shaped during the surgical procedure is also widely used. The aim of this study was to compare the above methods of orbital wall reconstructions. MATERIALS AND METHODS: In the first group (39 cases), patients were treated by means of computer-aided design/computer-aided manufacturing (CAD/CAM) milled individual implants made of ultra-high-molecular-weight polyethylene, dioxide zirconium and rapid prototyping titanium mesh pre-bent on an ABS model made by a three-dimensional (3D) printer...
February 17, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28317454/comparison-of-methods-for-estimating-glomerular-filtration-rate-in-head-and-neck-cancer-patients-treated-with-cisplatin
#5
Lotte Lindberg, Kasper Brødbæk, Erik G Hägerström, Jens Bentzen, Bent Kristensen, Bo Zerahn
Cisplatin is a chemotherapeutic agent widely used in the treatment of various solid tumors. Cisplatin induces nephrotoxicity and may lead to long-term reduction of kidney function. Consequently, determination of glomerular filtration rate (GFR) is used to monitor potential kidney damage. This study aimed to compare two commonly used algorithms for estimating GFR (eGFR) from plasma creatinine (PCr) with (51)Cr-EDTA clearance (CrCl) as a reference method. This was a retrospective single center study of 94 head and neck cancer patients treated with cisplatin...
March 20, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28315421/meal-box-schemes-a-convenient-way-to-avoid-convenience-food-uses-and-understandings-of-meal-box-schemes-among-danish-consumers
#6
Frej Daniel Hertz, Bente Halkier
The term convenience food is subject to diversification, lack of clarity and moral ambiguity. In this paper we address these issues and critically discuss convenience food by using empirical findings from a Danish study that deals with practitioners' uses of meal box schemes. The methodological design consists of thirteen individual interviews, four focus groups and some observations of cooking practices. We combine the empirical findings with a particular definition of convenience food by Brunner et al. (2010) and selected practice theoretical concepts...
March 14, 2017: Appetite
https://www.readbyqxmd.com/read/28314172/the-risk-of-cancer-in-the-offspring-and-parental-length-of-life
#7
Ruby Del Risco Kollerud, Karl Gerhard Blaasaas, Bjørgulf Claussen, Bente Oftedal, Øyvind Næss
BACKGROUND: We investigated if cancer onset in offspring is related to having short-lived parents for different cancer types and to see if there was a difference in smoking- and non-smoking related cancers. METHODS: Our study included 524,391 individuals born in Norway 1940-1950. All children were followed up for cancer from the age of 20 until they were between 59 and 69 years. Parental longevity was examined by grouping parental age of death into parents dying before 75 years of age and parents dying at 75 years of age or older...
March 14, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28301732/nanoengineering-heterogeneous-catalysts-by-atomic-layer-deposition
#8
Joseph A Singh, Nuoya Yang, Stacey F Bent
A new generation of catalysts is needed to meet society's energy and resource requirements. Current catalyst synthesis does not fully achieve optimum control of composition, size, and structure. Atomic layer deposition (ALD) is an emerging technique that allows synthesizing of highly controlled catalysts in the forms of films, nanoparticles, and single sites. The addition of ALD coatings can also be used to introduce promoters and improve the stability of traditional catalysts. Evolving research shows promise for applying ALD to understand catalytically active sites and create next-generation catalysts using advanced 3D nanostructures...
February 27, 2017: Annual Review of Chemical and Biomolecular Engineering
https://www.readbyqxmd.com/read/28301686/non-operative-control-of-cavitated-approximal-caries-lesions-in-primary-molars-a-prospective-evaluation-of-cases
#9
Niels V Hansen, Bente Nyvad
The effect of non-operative caries control at cavity level is often questioned. This prospective study of cases aims to evaluate the suitability of non-operative treatment of active cavitated approximal caries lesions in primary molars by assessing clinical changes of lesions over time. Further, we evaluate childrens and parents attitudes in response to non-operative cavity treatment. Thirty-nine children attending a community dental service, aged 5-11 years, joined the evaluation based on the following criteria: i) presence of at least one active cavitated caries lesion in the distal surface of first primary molar or mesial surface of the second primary molar extending up to two thirds into dentin assessed radiographically, ii) absence of spontaneous pain, iii) absence of pulpal or periapical pathology...
March 16, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28300744/a-modified-simple-technique-of-removing-the-lens-cortex-during-cataract-surgery
#10
Kyung Eun Han, Se Hoon Han, Dongkwon Lim, Min Chul Shin
We describe here a surgical technique of removing the remaining cortex after phacoemulsification without performing the conventional irrigation/aspiration (I/A) procedure. In this technique, the remaining cortex attached to the posterior capsule was separated and dissected into several pieces by continuous irrigation with balanced salt solution, which was supplied through a syringe attached to a bent, blunt-tip needle. Approximately, 10 s of manual irrigation separated most of the remaining cortex from the posterior capsule...
January 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28299900/development-of-a-robust-mammalian-cell-based-assay-for-studying-recombinant-%C3%AE-4-%C3%AE-1-3-%C3%AE-gabaa-receptor-subtypes
#11
Christina B Falk-Petersen, Rikke Søgaard, Kenneth L Madsen, Anders B Klein, Bente Frølund, Petrine Wellendorph
δ-Containing GABAA receptors are located extrasynaptically and mediate tonic inhibition. Their involvement in brain physiology positions them as interesting drug targets. There is thus a continued interest in establishing reliable recombinant expression systems for δ-containing GABAA receptors. Inconveniently, the recombinant expression of especially α4 β1/3 δ receptors has been found to be notoriously difficult, due to mixed receptor populations and/or stoichiometries and differential pharmacology depending on the expression system used...
March 16, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28297638/buckling-instabilities-and-complex-trajectories-in-a-simple-model-of-uniflagellar-bacteria
#12
Frank T M Nguyen, Michael D Graham
Observations of uniflagellar bacteria show that buckling instabilities of the hook protein connecting the cell body and flagellum play a role in locomotion. To understand this phenomenon, we develop models at varying levels of description with a particular focus on the parameter dependence of the buckling instability. A key dimensionless group called the flexibility number measures the hook flexibility relative to the thrust exerted by the flagellum; this parameter and the geometric parameters of the cell determine the stability of straight swimming...
March 14, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28296516/eye-disorders-among-adult-people-diagnosed-with-infantile-autism-in-childhood-a-longitudinal-case-control-study
#13
Svend Erik Mouridsen, Bente Rich, Torben Isager
PURPOSE: The objective of this study was to compare the prevalence and types of eye disorders in a clinical sample of 118 adult people diagnosed with infantile autism (IA) during childhood with 336 sex- and age-matched controls from the general population. METHODS: All participants were screened through the nationwide Danish National Hospital Register. The average observation time of both groups was 37.2 years, and mean age was 49.6 years, by the end of the observation period...
March 15, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28296175/bent-polytypic-znse-and-cdse-nanowires-probed-by-photoluminescence
#14
Yejin Kim, Hyung Soon Im, Kidong Park, Jundong Kim, Jae-Pyoung Ahn, Seung Jo Yoo, Jin-Gyu Kim, Jeunghee Park
Nanowires (NWs) have witnessed tremendous development over the past two decades owing to their varying potential applications. Semiconductor NWs often contain stacking faults due to the presence of coexisting phases, which frequently hampers their use. Herein, it is investigated how stacking faults affect the optical properties of bent ZnSe and CdSe NWs, which are synthesized using the vapor transport method. Polytypic zinc blende-wurtzite structures are produced for both these NWs by altering the growth conditions...
March 15, 2017: Small
https://www.readbyqxmd.com/read/28295122/epiphysiodesis-screw-bending
#15
Brett M Normandin, David J Tennent, Todd H Baldini, Alesia M Blanchard, Jason T Rhodes
Percutaneous epiphysiodesis using transphyseal screws is a common method for treatment of limb length discrepancy and angular deformity. The authors report 3 cases of a previously unreported complication following treatment with percutaneous epiphysiodesis using transphyseal screws: bending of the transphyseal screw. In each case, this rare complication was associated with difficult removal of the screw. This retrospective case report accessed the medical records of 3 children, 2 boys and 1 girl, 9 to 14 years old...
March 14, 2017: Orthopedics
https://www.readbyqxmd.com/read/28294605/a-uranyl-peroxide-dimer-in-the-gas-phase
#16
Phuong D Dau, Phuong V Dau, Linfeng Rao, Attila Kovács, John K Gibson
The gas-phase uranyl peroxide dimer, [(UO2)2(O2)(L)2](2+) where L = 2,2'-trifluoroethylazanediyl)bis(N,N'-dimethylacetamide), was synthesized by electrospray ionization of a solution of UO2(2+) and L. Collision-induced dissociation of this dimer resulted in endothermic O atom elimination to give [(UO2)2(O)(L)2](2+), which was found to spontaneously react with water via exothermic hydrolytic chemisorption to yield [(UO2)2(OH)2(L)2](2+). Density functional theory computations of the energies for the gas-phase reactions are in accord with observations...
March 15, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28292969/exercise-increases-human-skeletal-muscle-insulin-sensitivity-via-coordinated-increases-in-microvascular-perfusion-and-molecular-signaling
#17
Kim A Sjøberg, Christian Frøsig, Rasmus Kjøbsted, Lykke Sylow, Maximilian Kleinert, Andrew C Betik, Christopher S Shaw, Bente Kiens, Jørgen F P Wojtaszewski, Stephen Rattigan, Erik A Richter, Glenn K McConell
Insulin resistance is a major health risk and although exercise clearly improves skeletal muscle insulin sensitivity, the mechanisms are unclear. Here we show that initiation of a euglycemic hyperinsulinemic clamp four hours after single-legged exercise in humans increased microvascular perfusion (determined by contrast enhanced ultrasound) by 65% in the exercised leg and 25% in the rested leg (p<0.05) and leg glucose uptake increased 50% more (p<0.05) in the exercised leg than the rested leg. Importantly, infusion of the nitric oxide synthase inhibitor L-NMMA into both femoral arteries reversed the insulin stimulated increase in microvascular perfusion in both legs and abrogated the greater glucose uptake in the exercised compared with the rested leg...
March 14, 2017: Diabetes
https://www.readbyqxmd.com/read/28292885/heavy-strength-training-improves-running-and-cycling-performance-following-prolonged-submaximal-work-in-well-trained-female-athletes
#18
Olav Vikmoen, Bent R Rønnestad, Stian Ellefsen, Truls Raastad
The purpose of this study was to investigate the effects of adding heavy strength training to female duathletes' normal endurance training on both cycling and running performance. Nineteen well-trained female duathletes (VO2max cycling: 54 ± 3 ml∙kg(-1)∙min(-1), VO2max running: 53 ± 3 ml∙kg(-1)∙min(-1)) were randomly assigned to either normal endurance training (E, n = 8) or normal endurance training combined with strength training (E+S, n = 11). The strength training consisted of four lower body exercises [3 × 4-10 repetition maximum (RM)] twice a week for 11 weeks...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28291689/cartilage-suspension-using-a-poly-lactic-co-glycolic-acid-system
#19
Jae Hoon Jeong, Byung Hwi Kim, Dae Hee Kim, Baek-Kyu Kim, Chang Sik Pak, Eun Hee Kim, Chan Yeong Heo
BACKGROUND: This study aims to determine whether a bar-like implant made of poly lactic-co-glycolic acid (PLGA) could be used for cartilage suspension and whether the implant would be suitable for rhinoplasty. METHODS: Three types of in vivo animal experiments were performed. First, the ear cartilage was incised in a full-thickness pattern, and the PLGA system was placed between the upper and lower cartilage to offer support to the tissue. Second, after the ear cartilage was forcibly bent, an implant was placed in the cartilage...
February 17, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28287742/self-assembly-of-silver-nanowire-ring-structures-driven-by-compressive-force-of-liquid-droplet
#20
Baekhoon Seong, Hyun Sung Park, Ilkyung Chae, Hyungdong Lee, Xiaofeng Wang, Hyung-Seok Jang, Jaehyuck Jung, Changgu Lee, Liwei Lin, Doyoung Byun
In nanowire-dispersed in liquid droplets, the interplay between the surface tension of the liquid and the elasticity of the nanowire determines the final morphology of the bent or buckled nanowire. Here, we investigate the fabrication of a silver nanowire (Ag NW) ring generated by encapsulation inside fine droplets. We used a hybrid aerodynamic and electrostatic atomization method to ensure the generation of droplets with scalable size in the necessary regime for ring formation. We analytically identify the compressive force of the droplet driven by surface tension as the key mechanism for the self-assembly of ring structures...
March 13, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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