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Exercise and copd

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https://www.readbyqxmd.com/read/29676628/increasing-the-resolution-of-chronic-obstructive-pulmonary-disease-definition-lessons-from-a-cohort-with-remote-but-extensive-exposure-to-secondhand-tobacco-smoke
#1
Mehrdad Arjomandi, Siyang Zeng, Paul D Blanc, Warren M Gold
RATIONALE: The Global Initiative for Chronic Obstructive Lung Disease criteria require a ratio of forced expiratory volume in 1 second (FEV1 ) to forced vital capacity (FVC) (FEV1 /FVC) of less than 0.70 for the diagnosis of chronic obstructive pulmonary disease, whereas other criteria emphasize a lower limit of normal approach. However, the use of Global Initiative for Chronic Obstructive Lung Disease (or lower limit of normal) criteria may result in classification of many smokers with respiratory morbidities as not having chronic obstructive pulmonary disease...
April 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29673263/why-are-copd-patients-unable-to-complete-the-outpatient-pulmonary-rehabilitation-program
#2
Hulya Sahin, Ilknur Naz
This study aims to compare demographic and clinical characteristics of chronic obstructive pulmonary disease (COPD) patients who complete and fail to complete outpatient pulmonary rehabilitation (PR) program and to determine the reasons for not completing the program. Patients with COPD referred to the PR program were divided into two groups: Those who completed the program were classified as group 1 and those who did not complete were classified as group 2, and their data were compared. Patients who failed to complete the program were contacted through phone and asked why they ceased their participation in the program...
January 1, 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29671603/longitudinal-modeling-of-lung-function-trajectories-in-smokers-with-and-without-copd
#3
James C Ross, Peter J Castaldi, Michael H Cho, Craig P Hersh, Farbod N Rahaghi, Gonzalo V Sánchez-Ferrero, Margaret M Parker, Augusto A Litonjua, David Sparrow, Jennifer G Dy, Edwin K Silverman, George R Washko, Raúl San José Estépar
RATIONALE: The relationship between longitudinal lung function trajectories, chest computed tomography (CT) imaging, and genetic predisposition to COPD has not been explored. OBJECTIVES: 1) To model trajectories using a data-driven approach applied to longitudinal data spanning adulthood in the Normative Aging Study (NAS), and 2) to apply these models to demographically similar subjects in the COPDGene Study with detailed phenotypic characterization including chest CT...
April 19, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29665262/effects-of-inspiratory-muscle-training-in-copd-patients-a-systematic-review-and-meta-analysis
#4
REVIEW
Marc Beaumont, Patrice Forget, Francis Couturaud, Gregory Reychler
OBJECTIVES: In chronic obstructive pulmonary disease (COPD), quality of life and exercise capacity are altered in relationship to dyspnea. Benefits of inspiratory muscle training (IMT) on quality of life, dyspnea and exercise capacity were demonstrated, but when it is associated to pulmonary rehabilitation (PR), its efficacy on dyspnea is not demonstrated. The aim of this systematic review with meta analysis was to verify the effect of IMT using threshold devices in COPD patients on dyspnea, quality of life, exercise capacity and inspiratory muscles strength, and the added effect on dyspnea of IMT associated with PR (versus PR alone)...
April 17, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29664681/effect-of-bronchodilation-and-exercise-training-with-behavior-modification-on-exercise-tolerance-and-downstream-effects-on-symptoms-and-physical-activity-in-copd
#5
Thierry Troosters, François Maltais, Nancy Leidy, Kim L Lavoie, Maria Sedeno, Wim Janssens, Judith Garcia-Aymerich, Damijan Erzen, Dorothy De Sousa, Lawrence Korducki, Alan Hamilton, Jean Bourbeau
RATIONALE: Bronchodilation and exercise training (ExT) improve exercise tolerance in patients with chronic obstructive pulmonary disease (COPD); however, behavior modification is required to impact on daily physical activity (PA). OBJECTIVES: To assess whether tiotropium/olodaterol, ±ExT, would improve exercise endurance time (EET) and PA compared with placebo in patients participating in a self-management behavior-modification (SMBM) program. METHODS: A 12-week, randomized, partially double-blind, placebo-controlled, parallel-group trial in patients with COPD (PHYSACTO®; NCT02085161)...
April 17, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29652956/-tools-for-physical-activity-assessment-in-chronic-obstructive-pulmonary-disease
#6
Rodrigo Torres-Castro, Cristian Céspedes, Jordi Vilaró, Roberto Vera-Uribe, Marcelo Cano-Cappellacci, Diego Vargas
The prevalence and mortality of chronic obstructive pulmonary disease (COPD) is increasing in Chile, constituting a public health problem. Pulmonary and systemic consequences of COPD affect physical activity, as the disease progresses. There are multiple means for physical activity assessment, from low cost and easily applicable questionnaires to sophisticated laboratory tests. Physical inactivity is a modifiable risk factor for morbidity and mortality in patients with COPD. Physical activity interventions not only contribute to decrease the likelihood of mortality, but also protect from comorbidities, especially cardiovascular ones...
December 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29652760/influence-of-disease-severity-and-exercise-limitation-on-exercise-training-intensity-and-load-and-health-benefits-from-pulmonary-rehabilitation-in-patients-with-copd-an-exploratory-study
#7
Virginia C Huynh, Desi P Fuhr, Bradley W Byers, Anne-Marie Selzler, Linn E Moore, Michael K Stickland
PURPOSE: Some patients with chronic obstructive pulmonary disease (COPD) fail to achieve health benefits with pulmonary rehabilitation (PR). Exercise intensity and load represent stimulus for adaptation but it is unclear whether inappropriate exercise intensity and/or load are affected by severity of COPD, which may affect health benefits. The purpose was to determine whether COPD severity and/or the severity of pulmonary limitation to exercise (PLE) impacted exercising intensity or load and whether resultant intensity/load affected health outcomes derived from PR...
April 11, 2018: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/29652758/is-inspiratory-muscle-weakness-a-determinant-of-endurance-exercise-tolerance-during-niv-supported-exercise-in-patients-with-copd
#8
Rodrigo Koch, Gabriel Victor Guimarães Rapello, Paulo de Tarso Müller
PURPOSE: Previous research has reported that inspiratory muscle weakness is critical to decreased exercise tolerance and exercise tolerance improves with 10 cmH2O pressure support ventilation in patients with chronic obstructive pulmonary disease (COPD). The purpose of this study was to evaluate the effects of proportional assist ventilation (PAV) and continuous positive airway pressure (CPAP) compared with sham on exercise tolerance in patients with and without inspiratory muscle weakness...
April 11, 2018: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/29643055/findings-of-the-chronic-obstructive-pulmonary-disease-sitting-and-exacerbations-trial-copd-seat-in-reducing-sedentary-time-using-wearable-and-mobile-technologies-with-educational-support-randomized-controlled-feasibility-trial
#9
Mark W Orme, Amie E Weedon, Paula M Saukko, Dale W Esliger, Mike D Morgan, Michael C Steiner, John W Downey, Lauren B Sherar, Sally J Singh
BACKGROUND: Targeting sedentary time post exacerbation may be more relevant than targeting structured exercise for individuals with chronic obstructive pulmonary disease. Focusing interventions on sitting less and moving more after an exacerbation may act as a stepping stone to increase uptake to pulmonary rehabilitation. OBJECTIVE: The aim of this paper was to conduct a randomized trial examining trial feasibility and the acceptability of an education and self-monitoring intervention using wearable technology to reduce sedentary behavior for individuals with chronic obstructive pulmonary disease admitted to hospital for an acute exacerbation...
April 11, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29628896/inflammatory-and-metabolic-responses-to-different-resistance-training-on-chronic-obstructive-pulmonary-disease-a-randomized-control-trial
#10
Bruna S de Alencar Silva, Fábio S Lira, Fabrício E Rossi, Dionei Ramos, Juliana S Uzeloto, Ana P C F Freire, Fabiano F de Lima, Luís A Gobbo, Ercy M C Ramos
Background: Low-grade inflammation can be present in chronic obstructive pulmonary disease (COPD), which may affect the regulation of muscle protein and body metabolism. Regular exercise show improvement in muscle strength and dyspnea in patients with COPD, however, the response to training on inflammatory and metabolic disorders is unclear. In this study, we compared the effects of resistance training using weight machines and elastic resistance (bands and tubes) on the inflammatory and metabolic responses in patients with COPD...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29625777/tai-chi-and-pulmonary-rehabilitation-compared-for-treatment-naive-patients-with-copd-a-randomized-controlled-trial
#11
Michael I Polkey, Zhi-Hui Qiu, Lian Zhou, Meng-Duo Zhu, Ying-Xin Wu, Yong-Yi Chen, Sheng-Peng Ye, Yu-Shan He, Mei Jiang, Bai-Ting He, Bhavin Mehta, Nan-Shan Zhong, Yuan-Ming Luo
BACKGROUND: In COPD, functional status is improved by pulmonary rehabilitation (PR) but requires specific facilities. Tai Chi, which combines psychological treatment and physical exercise and requires no special equipment, is widely practiced in China and is becoming increasingly popular in the rest of the world. We hypothesized that Tai Chi is equivalent (ie, difference less than ±4 St. George's Respiratory Questionnaire [SGRQ] points) to PR. METHODS: A total of 120 patients (mean FEV1 , 1...
March 28, 2018: Chest
https://www.readbyqxmd.com/read/29595991/the-clinical-effects-of-manipulative-therapy-in-people-with-chronic-obstructive-pulmonary-disease
#12
Jayde Galletti, George Mcheileh, Andrew Hahne, Annemarie Louise Lee
OBJECTIVES: This study aimed to determine the effects of manipulative therapies (MT), including spinal manipulation, and diaphragmatic release techniques on lung function, exercise capacity, symptoms, and health-related quality of life (HRQOL) in people with chronic obstructive pulmonary disease (COPD). DESIGN: Systematic review. PARTICIPANTS: People diagnosed with COPD. INTERVENTION: Randomized controlled trials of MT (either with or without pulmonary rehabilitation [PR]) compared to other treatments (soft tissue [ST] therapy or sham therapy) applied in people with COPD were identified following the search of seven databases...
March 29, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29578103/acute-bronchodilator-therapy-does-not-reduce-wasted-ventilation-during-exercise-in-copd
#13
Amany F Elbehairy, Katherine A Webb, Pierantonio Laveneziana, Nicolle J Domnik, J Alberto Neder, Denis E O'Donnell
This randomized, double-blind, crossover study aimed to determine if acute treatment with inhaled bronchodilators, by improving regional lung hyperinflation and ventilation distribution, would reduce dead space-to-tidal volume ratio (VD /VT ); thus contributing to improved exertional dyspnea in COPD. Twenty COPD patients (FEV1  = 50 ± 15%predicted;mean ± SD) performed pulmonary function tests and symptom-limited constant-work rate exercise at 75% peak-work rate (with arterialized capillary blood gases) after nebulized bronchodilator (BD;ipratropium 0...
March 22, 2018: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29574168/low-leisure-based-sitting-time-and-being-physically-active-were-associated-with-reduced-odds-of-death-and-diabetes-in-people-with-chronic-obstructive-pulmonary-disease-a-cohort-study
#14
Zoe McKeough, Sonia Wing Mei Cheng, Jennifer Alison, Christine Jenkins, Mark Hamer, Emmanuel Stamatakis
QUESTIONS: In people with chronic obstructive pulmonary disease (COPD), are activity phenotypes (based on physical activity and recreational screen time) associated with mortality and cardiometabolic risk factors? DESIGN: Cohort study. PARTICIPANTS: People with COPD aged≥40years and who were current or ex-smokers were identified from the 2003 Scottish Health Survey. OUTCOME MEASURES: Data were collected regarding demographics, anthropometric measurements, medical history, physical activity, sedentary behaviour, health outcomes, and mortality...
March 21, 2018: Journal of Physiotherapy
https://www.readbyqxmd.com/read/29570476/patent-foramen-ovale-and-hypoxemia
#15
Mohammad K Mojadidi, Juan C Ruiz, Jason Chertoff, Muhammad O Zaman, Islam Y Elgendy, Ahmed N Mahmoud, Mohammad Al-Ani, Akram Y Elgendy, Nimesh K Patel, Ghanshyam Shantha, Jonathan M Tobis, Bernhard Meier
Patent foramen ovale (PFO), an embryonic remnant of the fetal circulation, is present in 20-25% of adults. While recent observational studies and clinical trials have established the link between PFO-mediated right-to-left shunting with cryptogenic stroke and migraine with aura, the role of a PFO in exacerbating hypoxemic medical conditions (i.e., sleep apnea, chronic obstructive pulmonary disease, pulmonary hypertension, platypnea-orthodeoxia, pulmonary arteriovenous malformation, high altitude pulmonary edema, and exercise desaturation) remains poorly evaluated...
March 22, 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29562888/ifn%C3%AE-3-4-locus-polymorphisms-and-ifn%C3%AE-3-circulating-levels-are-associated-with-copd-severity-and-outcomes
#16
Adrian Egli, Jyotshna Mandal, Desiree M Schumann, Michael Roth, Brad Thomas, D Lorne Tyrrell, Francesco Blasi, Kostantinos Kostikas, Wim Boersma, Branislava Milenkovic, Alicia Lacoma, Katharina Rentsch, Gernot G U Rohde, Renaud Louis, Joachim G Aerts, Tobias Welte, Antoni Torres, Michael Tamm, Daiana Stolz
BACKGROUND: Interferon lambdas (IFNLs) have important anti-viral/bacterial and immunomodulatory functions in the respiratory tract. How do IFNLs impact COPD and its exacerbations? METHODS: Five hundred twenty eight patients were recruited in a prospective observational multicentre cohort (PROMISE) study. The genetic polymorphisms (rs8099917 and rs12979860) within the IFNL3/4 gene region and circulating levels of IFNL3 in COPD patients were determined and associated with disease activity and outcome during a median follow-up of 24 months...
March 21, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29551329/air-quality-awareness-among-u-s-adults-with-respiratory-and-heart-disease
#17
Maria C Mirabelli, Tegan K Boehmer, Scott A Damon, Kanta D Sircar, Hilary K Wall, Fuyuen Y Yip, Hatice S Zahran, Paul L Garbe
INTRODUCTION: Poor air quality affects respiratory and cardiovascular health. Information about health risks associated with outdoor air quality is communicated to the public using air quality alerts. This study was conducted to assess associations of existing respiratory and heart disease with three aspects of air quality awareness: awareness of air quality alerts, discussing with a health professional strategies to reduce air pollution exposure, and avoiding busy roads to reduce air pollution exposure when walking, biking, or exercising outdoors...
March 15, 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29549005/influence-of-dietary-nitrate-supplementation-on-lung-function-and-exercise-gas-exchange-in-copd-patients
#18
Mehrdad Behnia, Courtney M Wheatley, Alberto Avolio, Bruce D Johnson
BACKGROUND: During exercise as pulmonary blood flow rises, pulmonary capillary blood volume increases and gas exchange surface area expands through distention and recruitment. We have previously demonstrated that pulmonary capillary recruitment is limited in COPD patients with poorer exercise tolerance. Hypoxia and endothelial dysfunction lead to pulmonary vascular dysregulation possibly in part related to nitric oxide related pathways. PURPOSE: To determine if increasing dietary nitrate might influence lung surface area for gas exchange and subsequently impact exercise performance...
March 13, 2018: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/29547535/patterns-of-time-use-across-the-chronic-obstructive-pulmonary-disease-severity-spectrum
#19
Toby Hunt, Marie T Williams, Timothy S Olds, Dorothea Dumuid
Descriptions of time use patterns in people with chronic obstructive pulmonary disease (COPD) are scarce and the relationship between use-of-time and COPD severity remains unclear. This study aimed to describe a typical day for people with COPD and to explore the differences in time-use patterns across the Body Mass-Index, Airflow Obstruction, Dyspnoea and Exercise Capacity (BODE) index using compositional analyses. Using a cross-sectional design, 141 adults with clinically stable COPD had their demographics, objective measures of function (pulmonary, exercise capacity and physical activity), and self-reported COPD-related impairment recorded...
March 16, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29547003/home-oxygen-in-chronic-obstructive-pulmonary-disease
#20
Yves Lacasse, Ai-Yui M Tan, François Maltais, Jerry A Krishnan
Two landmark trials conducted more than 35 years ago provided scientific evidence that, under very specific circumstances, long-term oxygen therapy (LTOT) may prolong life. These two trials enrolled 290 patients with chronic obstructive pulmonary disease (COPD) and severe daytime hypoxemia documented by direct arterial blood gas measurement. From this moment, LTOT became a standard of care and the indications for oxygen therapy have expanded to include nocturnal oxygen therapy for isolated nocturnal oxygen desaturation, ambulatory oxygen to correct exercise-induced desaturation, and short-burst oxygen to relieve dyspnea...
March 16, 2018: American Journal of Respiratory and Critical Care Medicine
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