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https://www.readbyqxmd.com/read/29916844/positive-airway-pressure-devices-for-the-management-of-breathlessness
#1
Rebecca F D'Cruz, Georgios Kaltsakas, Eui-Sik Suh, Patrick B Murphy, Nicholas Hart
PURPOSE OF REVIEW: Breathlessness is a common symptom in many chronic diseases and may be refractory to pharmacotherapy. In this review, we discuss the pathophysiology of breathlessness and the role of positive airway pressure (PAP) devices to ameliorate it. RECENT FINDINGS: Breathlessness is directly related to neural respiratory drive, which can be modified by addressing the imbalance between respiratory muscle load and capacity. Noninvasive PAP devices have been applied to patients limited by exertional breathless and, as the disease progresses, breathlessness at rest...
June 18, 2018: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/29916565/-care-related-intervention-in-rehabilitative-pneumology-pulmonary-rehabilitation-in-chronic-obstructive-broncopneumopathies-copd-can-benefit-from-a-multidisciplinary-approach
#2
Michele Vitacca, Dina Visca, Antonio Spanevello
OBJECTIVES: Chronic Obstructive Pulmonary Disease (COPD) is a common, preventable and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation. Cardiovascular diseases, osteoporosis, depression/anxiety, musculoskeletal impairment and obstructive sleep apnea are frequent and important comorbidities in COPD, often under-diagnosed, and associated with poor health status and prognosis. METHODS: Pulmonary rehabilitation improves symptoms, quality of life, pulmonary function, and health care in patients with chronic respiratory disease...
February 2018: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
https://www.readbyqxmd.com/read/29915733/prevalence-of-pulmonary-artery-hypertension-in-patients-of-chronic-obstructive-pulmonary-disease-and-its-correlation-with-stages-of-chronic-obstructive-pulmonary-disease-exercising-capacity-and-quality-of-life
#3
Kamlesh Kumar Gupta, Bidyut Roy, Shyam Chand Chaudhary, Arvind Mishra, M L Patel, Jitendra Singh, Vivek Kumar
Background: Pulmonary arterial hypertension (PAH) is a complication of chronic obstructive pulmonary disease (COPD) in advance stages, and its presence indicates poor prognosis. Aims and Objective: The present study was design to know the prevalence of PAH in patients with COPD and its correlation with stages of COPD, exercising capacity, and quality of life. Materials and Methods: It is a cross-sectional prevalence study over a period of 1 year from August 2015 to July 2016...
January 2018: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29910123/clinical-characteristics-of-copd-patients-with-early-onset-desaturation-in-the-6-minute-walk-test
#4
I García-Talavera, J M Figueira-Gonçalves, N Gurbani, L Pérez-Méndez, A Pedrero-García
BACKGROUND: Exercise-induced desaturation in chronic obstructive pulmonary disease (COPD) frequently has prognostic implications. Desaturation within the first minute of the walk 6-minute walk test will probably also occur in daily life activities and translate into hypoxaemic respiratory failure at rest in later years. This study aimed at comparing these patients with those who desaturate after the first minute and determine potential markers. METHODS: We conducted a cross-sectional, retrospective study collecting data on respiratory function tests, cardiovascular comorbidity, body mass index, pack-year index, 6-minute walk test outcomes, BODE index, and Charlson comorbidity index...
June 14, 2018: Pulmonology
https://www.readbyqxmd.com/read/29909933/community-pharmacist-led-employer-based-wellness-services-a-pilot-study
#5
Justin Gatwood, Rhonda Hanley, Joe S Moore, Kenneth Hohmeier
The emphasis that United States employers are placing on employee wellness continues to grow; however, most attention has been paid to larger firms to gauge return-on-investment from a larger pool of enrollees. With fewer resources available to fund expansive wellness programs, smaller businesses need a cost-effective mechanism to provide such benefits. As the most accessible healthcare provider, community pharmacists are in an ideal position to support certain wellness programs for smaller businesses. This research piloted a community pharmacist-led, employer-sponsored wellness program for a self-insured financial services company in Tennessee...
June 12, 2018: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29906421/effectiveness-of-pulmonary-rehabilitation-in-patients-with-chronic-obstructive-pulmonary-disease-with-different-degrees-of-static-lung-hyperinflation
#6
Michiel J E G W Vanfleteren, Maud Koopman, Martijn A Spruit, Herman-Jan Pennings, Frank Smeenk, Willem Pieters, Jan J A M van den Bergh, Arent-Jan Michels, Emiel F M Wouters, Miriam T J Groenen, Frits M E Franssen, Lowie E G W Vanfleteren
OBJECTIVE: To evaluate the effect of pulmonary rehabilitation (PR) on exercise performance and quality of life in patients with chronic obstructive pulmonary disease (COPD) with different degrees of static lung hyperinflation (LH). DESIGN: Retrospective cohort study. SETTING: Pulmonary Rehabilitation Network. PARTICIPANTS: A cohort of 1981 patients with COPD (55% males; age: 66.8 ± 9.3y; FEV1%: 50.7 ± 19.5; RV%: 163...
June 12, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29903607/improvement-of-physical-activity-in-chronic-obstructive-pulmonary-disease-by-pulmonary-rehabilitation-and-pharmacological-treatment
#7
REVIEW
Takanobu Shioya, Susumu Sato, Masahiro Iwakura, Hitomi Takahashi, Yoshino Terui, Sachiko Uemura, Masahiro Satake
Physical activity (PA) is defined as bodily movement produced by skeletal muscles with energy expenditure beyond resting levels. PA is closely related to reduced morbidity and mortality in chronic obstructive pulmonary disease (COPD). Self-report questionnaires are often subject to recall bias, correlating poorly with objectively qualified PA, and do not provide an accurate estimate of free-living energy expenditure. PA may be objectively evaluated by newly developed tri-axial accelerometers by quantifying steps or body movements over a period of time...
June 11, 2018: Respiratory Investigation
https://www.readbyqxmd.com/read/29898875/clinical-and-molecular-markers-in-copd
#8
I Gonçalves, M J Guimarães, M van Zeller, F Menezes, J Moita, P Simão
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease, and there is a clinical need for validated markers and biomarkers that can contribute to the assessment of patients, risk prediction, treatment guidance, and assessment of response. Although according to the 2018 GOLD guidelines clinically useful biomarkers for COPD patients in stable condition have yet to be identified, several clinical markers and biomarkers have been proposed for COPD. These include isolated clinical markers, such as symptoms and Health Status assessment, exercise tests, function tests and imaging, and also composite scores and molecular markers...
June 10, 2018: Pulmonology
https://www.readbyqxmd.com/read/29888577/-electroacupuncture-intervention-improved-pulmonary-function-via-promoting-immunoregulation-in-chronic-obstructive-pulmonary-disease-rats
#9
Juan Tong, Fu-Chu Chen, Gui-Yuan Li, Xiang-Ao Kong, Ying He, Hong Yao
OBJECTIVE: To observe the immunoregulatory effect of electroacupuncture (EA) intervention for muscular dystrophy chronic obstructive pulmonary disease (COPD) rats, so as to investigate its underlying mechanism in improving respiratory function. METHODS: Forty male SD rats were randomly divided into 5 groups: normal, model, EA, exercise, and EA+ exercise ( n =8 in each). The muscular dystrophy COPD model was established by placing the rats in a closed box to be exposed to cigarette smoke (3-10 cigarettes/time) for 60 min, twice daily, 6 days a week for 90 days...
April 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29881266/acute-exacerbation-of-copd-during-pulmonary-rehabilitation-outcomes-and-risk-prediction
#10
Bertrand Herer, Thierry Chinet
Purpose: This study was performed to examine acute exacerbation of COPD (AECOPD) during pulmonary rehabilitation (PR) and the usefulness of multidimensional indices (MIs) to predict AECOPD at enrolment in PR. Patients and methods: A 4-week PR program (PRP) was implemented for 125 consecutive patients with COPD. At baseline and PRP completion, we recorded the FEV1 , 6-minute walk test, peak work rate at cardiopulmonary testing, modified Medical Research Council score, and COPD Assessment Test (CAT) score...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29873642/-lung-and-heart-interaction-chronic-obstructive-pulmonary-disease-and-ischemic-heart-disease
#11
Sara Roversi, Leonardo M Fabbri
The interaction between the lung and the heart is a vast, complex, and fascinating topic and, from a clinical point of view, disorders of the one often influence and promote disorders of the other. This is especially true for chronic diseases, with chronic obstructive pulmonary disease (COPD) and ischemic heart disease (IHD) representing a classic example. Epidemiologic data indicate that cardiovascular diseases are frequent in patients with COPD, and vice versa. Accordingly, rates of IHD in COPD vary from 4% up to 60%, while, on the other hand, COPD has been reported in up to 30% of patients with coronary artery disease...
March 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29872289/effectiveness-of-water-based-liuzijue-exercise-on-respiratory-muscle-strength-and-peripheral-skeletal-muscle-function-in-patients-with-copd
#12
Weibing Wu, Xiaodan Liu, Jingxin Liu, Peijun Li, Zhenwei Wang
Objects: The purpose of this study was to quantitatively assess the effects of water-based Liuzijue exercise on patients with COPD and compare it with land-based Liuzijue exercise. Materials and methods: Participants were randomly allocated to one of three groups: the water-based Liuzijue exercise group (WG), the land-based Liuzijue exercise group (LG), and the control group (CG). CG participants accepted no exercise intervention, while training groups performed Liuzijue exercise according to Health Qigong Liuzijue (People's Republic of China) in different environments for 60-min sessions twice a week for 3 months...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29867117/facilitators-and-barriers-to-physical-activity-following-pulmonary-rehabilitation-in-copd-a-systematic-review-of-qualitative-studies
#13
REVIEW
Hayley Robinson, Veronika Williams, Ffion Curtis, Christopher Bridle, Arwel W Jones
Pulmonary rehabilitation has short-term benefits on dyspnea, exercise capacity and quality of life in COPD, but evidence suggests these do not always translate to increased daily physical activity on a patient level. This is attributed to a limited understanding of the determinants of physical activity maintenance following pulmonary rehabilitation. This systematic review of qualitative research was conducted to understand COPD patients' perceived facilitators and barriers to physical activity following pulmonary rehabilitation...
June 4, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29866200/an-evaluation-of-the-short-physical-performance-battery-following-pulmonary-rehabilitation-in-patients-with-chronic-obstructive-pulmonary-disease
#14
Petra Larsson, Christine Råheim Borge, Malin Nygren-Bonnier, Anners Lerdal, Anne Edvardsen
OBJECTIVE: There is a need for simple tools to evaluate physical performance in patients with COPD before and after pulmonary rehabilitation. The aims of this study were to evaluate changes in short physical performance battery (SPPB)-scores in patients with COPD after a 4-week pulmonary rehabilitation program; explore possible relationships between SPPB-scores and exercise capacity (6-min walk distance), dyspnea (modified Medical Research Council's dyspnea scale), disease-specific quality of life (COPD assessment test), and pulmonary function (predicted forced expiratory volume in one second) at baseline; and explore if changes in SPPB-scores are related to changes in exercise capacity, dyspnea, and disease-specific quality of life following pulmonary rehabilitation...
June 4, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29857998/clinical-impact-of-the-lower-limit-of-normal-of-fev-1-fvc-on-detecting-chronic-obstructive-pulmonary-disease-a-follow-up-study-based-on-cross-sectional-data
#15
Sha Liu, Yumin Zhou, Shiliang Liu, Weifeng Zou, Xiaochen Li, Chenglong Li, Zhishan Deng, Jinzhen Zheng, Bing Li, Pixin Ran
BACKGROUND: Criteria of obstruction that establish a diagnosis of COPD have been debated in recent years. We carried out a follow-up study to assess the impact of the new LLN reference equation for Chinese on detecting COPD compared with the traditional 0.7fixed criteria. METHODS: We examined the prevalence and characteristics of airflow limitation for a non-child population using post-bronchodilator airflow with both age-dependent predicted lower limit of the normal value and fixed-ratio spirometric criterion...
June 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29857994/effects-of-exercise-training-on-cognition-in-chronic-obstructive-pulmonary-disease-a-systematic-review
#16
REVIEW
Laura Desveaux, Samantha L Harrison, Jean-François Gagnon, Roger S Goldstein, Dina Brooks, Véronique Pepin
BACKGROUND: As exercise may mitigate cognitive decline in individuals with chronic obstructive pulmonary disease (COPD), its effect has been evaluated in a number of clinical trials. The objective of the present systematic review was to describe the impact of exercise training on cognition in COPD. METHODS: Electronic searches of four databases were performed from inception until March 24, 2015 and last updated 23rd October 2017. Included studies reported on at least one cognitive outcome before and after a formal exercise-training program in individuals with COPD...
June 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29845600/neuromuscular-electrostimulation-for-adults-with-chronic-obstructive-pulmonary-disease
#17
REVIEW
Kylie Hill, Vinicius Cavalheri, Sunita Mathur, Marc Roig, Tania Janaudis-Ferreira, Priscila Robles, Thomas E Dolmage, Roger Goldstein
BACKGROUND: In people with chronic obstructive pulmonary disease (COPD), the use of neuromuscular electrostimulation (NMES) either alone, or together with conventional exercise training, might improve the condition of the peripheral muscles, increase exercise capacity and functional performance, reduce symptoms and improve health-related quality of life (HRQoL). OBJECTIVES: To determine the effects of NMES, applied in isolation or concurrently with conventional exercise training to one or more peripheral muscles, on peripheral muscle force and endurance, muscle size, exercise capacity, functional performance, symptoms, HRQoL and adverse events in people with COPD...
May 29, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29844808/assessment-of-anti-reflux-treatment-on-pulmonary-ventilation-function-and-inflammatory-cytokines-in-patients-with-stable-chronic-obstructive-pulmonary-disease-combined-with-gastroesophageal-reflux
#18
Hang Liu
Compelling evidence has demonstrated that systemic inflammation among patients with stable chronic obstructive pulmonary disease (COPD) is linked with increased levels of inflammatory cytokines. The aim of the present study was to investigate the effects associated with anti-reflux treatment on pulmonary ventilation function and inflammatory cytokines in patients with stable COPD and gastroesophageal reflux (GER). One hundred and thirty-six stable COPD and GER patients were recruited for the study and randomly designated into the routine treatment and the anti GER groups...
June 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29802649/effect-of-endurance-versus-resistance-training-on-local-muscle-and-systemic-inflammation-and-oxidative-stress-in-copd
#19
C K Ryrsø, P Thaning, C Siebenmann, C Lundby, P Lange, B K Pedersen, Y Hellsten, U W Iepsen
Limb muscle dysfunction in patients with COPD may be associated with local muscle and/or systemic inflammation, and therefore, we investigated whether exercise training altered markers of inflammation and oxidative stress. We obtained vastus lateralis muscle biopsies and venous blood samples from patients with COPD (n=30) before and after 8 weeks of resistance training (RT) (n=15) or endurance training (ET) (n=15). Healthy age-matched subjects were included as baseline controls (n=8). Inflammatory markers in muscle and systemically were determined by interleukins (IL), tumour necrosis factor alfa (TNF-α), leukocyte concentration together with immunohistochemical staining for macrophages...
May 26, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29799805/genetic-variants-predicting-aerobic-capacity-response-to-training-are-also-associated-with-skeletal-muscle-oxidative-capacity-in-moderate-to-severe-copd
#20
Alessandra Adami, Brian D Hobbs, Merry-Lynn McDonald, Richard Casaburi, Harry B Rossiter
Muscle oxidative capacity is a major determinant of maximum oxygen uptake (V̇O2max ). V̇O2max predicts survival in humans. Muscle oxidative capacity is low in chronic obstructive pulmonary disease (COPD), and can be assessed from the muscle oxygen consumption recovery rate constant ( k) using near-infrared spectroscopy. We hypothesized that 11 SNPs previously associated with the increase in V̇O2max following exercise training, would correlate with k in 152 non-Hispanic White and African American smokers with and without COPD...
May 25, 2018: Physiological Genomics
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