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Alternate day fasting

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https://www.readbyqxmd.com/read/28229567/repeated-sprint-training-in-the-fasted-state-during-ramadan-morning-or-evening-training
#1
Asma Aloui, Tarak Driss, Hana Baklouti, Hamdi Jaafar, Omar Hammouda, Karim Chamari, Nizar Souissi
BACKGROUND: The present study assessed the optimal moment-of-day for repeated-sprint training in the fasted state during Ramadan. METHODS: Thirty amateur soccer players were randomly assigned to a morning training group (MTG, training at ~08:00 a.m., n = 10), an evening training group (ETG, training at ~06:00 p.m., n = 10), and a control group (n = 10). Training sessions, conducted on alternate days, consisted of 3 sets of 6 × 40-m shuttle sprints (2 × 20 m with 180° direction changes)...
February 22, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28225054/nutritional-adequacy-of-diets-for-adolescents-with-overweight-and-obesity-considerations-for-dietetic-practice
#2
N B Lister, M L Gow, K Chisholm, A Grunseit, S P Garnett, L A Baur
BACKGROUND/OBJECTIVES: Adolescents have unique nutrient requirements due to rapid growth and development. High rates of obesity in adolescents require a variety of diet interventions to achieve weight loss under clinical supervision. The aim of this study is to examine the nutritional adequacy of energy-restricted diets for adolescents. SUBJECTS/METHODS: Three popular diets were modelled for 7 days and assessed by comparing the nutrient profile to the Australian Nutrient Reference Values...
February 22, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28212832/motor-dysfunction-and-alterations-in-glutathione-concentration-cholinesterase-activity-and-bdnf-expression-in-substantia-nigra-pars-compacta-in-rats-with-pedunculopontine-lesion
#3
Lisette Blanco-Lezcano, Javier Jimenez-Martin, Mei-Li Díaz-Hung, Esteban Alberti-Amador, Maylin Wong-Guerra, Ma Elena González-Fraguela, Bárbara Estupiñán-Díaz, Teresa Serrano-Sánchez, Liliana Francis-Turner, Susana Delgado-Ocaña, Yanier Núñez-Figueredo, Yamilé Vega-Hurtado, Isabel Fernández-Jiménez
Pedunculopontine nucleus (PPN) has been considered a critically important region in the regulation of some of the physiological functions that fail during the progression of Parkinson's disease (PD). In this paper, the effects of unilateral neurotoxic lesion of the PPN [through the injection of N-methyl-D-aspartate (NMDA) solution (concentration: 0.1 M; volume: 0.5 µL)] in motor execution and gait disorders and the changes in cellular and molecular indicators in rat nigral tissue were evaluated. The motor execution was assessed using the beam test (BT) and the gait disorders by footprint test...
February 14, 2017: Neuroscience
https://www.readbyqxmd.com/read/28193647/piperaquine-population-pharmacokinetics-and-cardiac-safety-in-cambodia
#4
Pattaraporn Vanachayangkul, Chanthap Lon, Michele Spring, Sommethy Sok, Winita Ta-Aksorn, Chanikarn Kodchakorn, Sut-Thang Pann, Soklyda Chann, Mali Ittiverakul, Sabaithip Sriwichai, Nillawan Buathong, Worachet Kuntawunginn, Mary So, Theng Youdaline, Erin Milner, Mariusz Wojnarski, Charlotte Lanteri, Jessica Manning, Satharath Prom, Mark Haigney, Louis Cantilena, David Saunders
Despite rising resistance, dihydroartemisinin-piperaquine (DP) remains a first line therapy for uncomplicated malaria in many parts of Cambodia. While generally well-tolerated as a 3-day regimen, compressed 2-day regimens were associated with treatment-limiting cardiac repolarization effects in a recent clinical trial. To better estimate the risks of piperaquine concentration on QT interval prolongation, we pooled data from 3 randomized clinical trials between 2010 and 2014 in northern Cambodia. A population pharmacokinetic model was developed to compare exposure-response relationships between 2-day (2DP) and 3-day (3DP) regimens while accounting for differences in regimen and sample collection times between studies...
February 13, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28192975/third-harmonic-scattering-for-fast-and-sensitive-screening-of-the-second-hyperpolarizability-in-solution
#5
Nick Van Steerteghem, Koen Clays, Thierry Verbiest, Stijn Van Cleuvenbergen
Organic materials are promising candidates for integration in optical network components allowing fast communication. Ultimate speeds can be obtained by exploiting third-order nonlinear optical light-matter interactions that ultimately rely on the molecular second hyperpolarizability (γ). The exploration of molecular structure-property relations is crucial to optimize γ but requires state of the art measurement techniques which are both sensitive and efficient. Unfortunately, present-day methods for probing the performance of third-order nonlinear optical (NLO) materials fail to meet at least one of those requirements...
February 15, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28177396/growth-heterogeneity-in-broiler-breeder-pullets-is-settled-before-the-onset-of-feed-restriction-but-is-not-predicted-by-size-at-hatch
#6
C Lindholm, J Jönsson, A Calais, A Middelkoop, N Yngwe, E Berndtson, J J Lees, E Hult, J Altimiras
Uniform growth is a desirable trait in all large-scale animal production systems because it simplifies animal management and increases profitability. In parental broiler flocks, so-called broiler breeders, low growth uniformity is largely attributed to the feed competition that arises from quantitatively restricted feeding. As feed restriction is crucial to maintaining healthy and fertile breeders, several practices for reducing feed competition and the associated growth heterogeneity have been suggested and range from nutrient dilution by increasing fiber content in feed to intermittent fasting with increased portion size ("skip a day"), but no practice appears to be entirely effective...
January 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28146063/consuming-two-eggs-per-day-as-compared-to-an-oatmeal-breakfast-decreases-plasma-ghrelin-while-maintaining-the-ldl-hdl-ratio
#7
Amanda Missimer, Diana M DiMarco, Catherine J Andersen, Ana Gabriela Murillo, Marcela Vergara-Jimenez, Maria Luz Fernandez
Eggs contain high quality protein, vitamins, minerals and antioxidants, yet regular consumption is still met with uncertainty. Therefore, the purpose of this study was to compare the effects of consuming two eggs per day or a heart-healthy oatmeal breakfast on biomarkers of cardiovascular disease (CVD) risk and satiety measures in a young, healthy population. Fifty subjects participated in a randomized crossover clinical intervention; subjects were randomly allocated to consume either two eggs or one packet of oatmeal per day for breakfast for four weeks...
29, 2017: Nutrients
https://www.readbyqxmd.com/read/28138096/ptf1a-ela3l-cells-are-developmentally-maintained-progenitors-for-exocrine-regeneration-following-extreme-loss-of-acinar-cells-in-zebrafish-larvae
#8
Nicole Schmitner, Kenji Kohno, Dirk Meyer
The exocrine pancreas displays a significant capacity for regeneration and renewal. In humans and mammalian model systems, the partial loss of exocrine tissue, such as after acute pancreatitis or partial pancreatectomy induces rapid recovery via expansion of surviving acinar cells. In mouse it was further found that an almost complete removal of acinar cells initiates regeneration from a currently not well-defined progenitor pool. Here we used the zebrafish as an alternative model to study cellular mechanisms of exocrine regeneration following an almost complete removal of acinar cells...
January 30, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28115622/robust-and-rapid-algorithms-facilitate-large-scale-whole-genome-sequencing-downstream-analysis-in-an-integrative-framework
#9
Miaoxin Li, Jiang Li, Mulin Jun Li, Zhicheng Pan, Jacob Shujui Hsu, Dajiang J Liu, Xiaowei Zhan, Junwen Wang, Youqiang Song, Pak Chung Sham
Whole genome sequencing (WGS) is a promising strategy to unravel variants or genes responsible for human diseases and traits. However, there is a lack of robust platforms for a comprehensive downstream analysis. In the present study, we first proposed three novel algorithms, sequence gap-filled gene feature annotation, bit-block encoded genotypes and sectional fast access to text lines to address three fundamental problems. The three algorithms then formed the infrastructure of a robust parallel computing framework, KGGSeq, for integrating downstream analysis functions for whole genome sequencing data...
January 23, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28115614/feedback-traps-for-virtual-potentials
#10
REVIEW
Momčilo Gavrilov, John Bechhoefer
Feedback traps are tools for trapping and manipulating single charged objects, such as molecules in solution. An alternative to optical tweezers and other single-molecule techniques, they use feedback to counteract the Brownian motion of a molecule of interest. The trap first acquires information about a molecule's position and then applies an electric feedback force to move the molecule. Since electric forces are stronger than optical forces at small scales, feedback traps are the best way to trap single molecules without 'touching' them (e...
March 6, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28109417/associations-of-cooking-with-dietary-intake-and-obesity-among-supplemental-nutrition-assistance-program-participants
#11
Lindsey Smith Taillie, Jennifer M Poti
INTRODUCTION: Participation in the Supplemental Nutrition Assistance Program (SNAP) may help ease economic and time constraints of cooking, helping low-income households prepare healthier meals. Therefore, frequent cooking may be more strongly associated with improved dietary outcomes among SNAP recipients than among income-eligible non-recipients. Alternately, increased frequency of home-cooked meals among SNAP participants may be beneficial simply by replacing fast food intake. This study quantified the association between home cooking and fast food with diet intake and weight status among SNAP recipients...
February 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28107043/the-impact-of-meal-timing-on-cardiometabolic-syndrome-indicators-in-shift-workers
#12
Hylton E Molzof, Michael D Wirth, James B Burch, Nitin Shivappa, James R Hebert, Russell L Johnson, Karen L Gamble
The aims of this study were to 1) compare the inflammatory potential of night- and day-shift nurses' diets with regard to time of day and work status and 2) explore how the timing of food intake during work and off-work is associated with cardiometabolic syndrome (CMS) risk factors between these two groups. Female nurses (N = 17; 8 day-shift and 9 night-shift) reported food intake over 9 days. On a middle day off of work, metabolic parameters were measured after an overnight fast. Energy/macronutrient intake and inflammatory potential of dietary intake (as assessed via the Dietary Inflammatory Index(TM)) were calculated for nurses' workdays, work nights, off-work days, and off-work nights...
January 20, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28094665/fdg-pet-reproducibility-in-tumor-bearing-mice-comparing-a-traditional-suv-approach-with-a-tumor-to-brain-tissue-ratio-approach
#13
Morten Busk, Ole L Munk, Steen Jakobsen, Jørgen Frøkiær, Jens Overgaard, Michael R Horsman
BACKGROUND: Current [F-18]-fluorodeoxyglucose positron emission tomography (FDG-PET) procedures in tumor-bearing mice typically includes fasting, anesthesia, and standardized uptake value (SUV)-based quantification. Such procedures may be inappropriate for prolonged multiscan experiments. We hypothesize that normalization of tumor FDG retention relative to a suitable reference tissue may improve accuracy as this method may be less susceptible to uncontrollable day-to-day changes in blood glucose levels, physical activity, or unnoticed imperfect tail vein injections...
January 17, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28074050/enhanced-dereplication-of-fungal-cultures-via-use-of-mass-defect-filtering
#14
Noemi D Paguigan, Tamam El-Elimat, Diana Kao, Huzefa A Raja, Cedric J Pearce, Nicholas H Oberlies
Effective and rapid dereplication is a hallmark of present-day drug discovery from natural sources. This project strove to both decrease the time and expand the structural diversity associated with dereplication methodologies. A 5 min liquid chromatographic run time employing heated electrospray ionization (HESI) was evaluated to determine whether it could be used as a faster alternative over the 10 min ESI method we reported previously. Results revealed that the 5 min method was as sensitive as the 10 min method and, obviously, was twice as fast...
January 11, 2017: Journal of Antibiotics
https://www.readbyqxmd.com/read/28073560/an-alternative-explanation-for-cyanobacterial-scum-formation-and-persistence-by-oxygenic-photosynthesis
#15
E Aparicio Medrano, R E Uittenbogaard, B J H van de Wiel, L M Dionisio Pires, H J H Clercx
The cause of persistent cyanobacteria scum formation in lakes is an unresolved subject. Scum refers to the event in which cyanobacteria are at the water surface of a lake. Factors like low turbulence levels, long day-light, high water temperatures and the buoyant capacity of cyanobacterial cells play a role in the occurrence of scums. However, they do not explain why scums are observed at periods during the day when according to theory they should have disappeared into the deeper water layers. In this study, we present an alternative explanation...
December 2016: Harmful Algae
https://www.readbyqxmd.com/read/28045956/recombinase-polymerase-amplification-assay-a-simple-fast-and-cost-effective-alternative-to-real-time-pcr-for-specific-detection-of-feline-herpesvirus-1
#16
Jianchang Wang, Libing Liu, Jinfeng Wang, Xiaoxia Sun, Wanzhe Yuan
Feline herpesvirus 1 (FHV-1), an enveloped dsDNA virus, is one of the major pathogens of feline upper respiratory tract disease (URTD) and ocular disease. Currently, polymerase chain reaction (PCR) remains the gold standard diagnostic tool for FHV-1 infection but is relatively expensive, requires well-equipped laboratories and is not suitable for field tests. Recombinase polymerase amplification (RPA), an isothermal gene amplification technology, has been explored for the molecular diagnosis of infectious diseases...
2017: PloS One
https://www.readbyqxmd.com/read/28045493/inhalation-and-oropharyngeal-aspiration-exposure-to-rod-like-carbon-nanotubes-induce-similar-airway-inflammation-and-biological-responses-in-mouse-lungs
#17
Pia Kinaret, Marit Ilves, Vittorio Fortino, Elina Rydman, Piia Karisola, Anna Lähde, Joonas Koivisto, Jorma Jokiniemi, Henrik Wolff, Kai Savolainen, Dario Greco, Harri Alenius
Carbon nanotubes (CNTs) have the potential to impact technological and industrial progress, but their production and use may, in some cases, cause serious health problems. Certain rod-shaped multiwalled CNTs (rCNTs) can, in fact, induce severe asbestos-like pathogenicity in mice, including granuloma formation, fibrosis, and even cancer. Evaluating the comparability between alternative hazard assessment methods is needed to ensure fast and reliable evaluation of the potentially adverse effects of these materials...
January 11, 2017: ACS Nano
https://www.readbyqxmd.com/read/28043305/accuracy-of-non-fasting-lipid-profile-for-the-assessment-of-lipoprotein-coronary-risk
#18
Safia Fatima, Aamir Ijaz, Tariq Bin Sharif, Dilshad Ahmad Khan, Amer Siddique
OBJECTIVE: To determine the diagnostic accuracy of non-fasting lipid profile in the diagnosis of hyperlipidemia, taking fasting lipid profile as gold standard, in adult population. STUDY DESIGN: Cross-sectional validation study. PLACE AND DURATION OF STUDY: Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology, Rawalpindi, from July to December 2014. METHODOLOGY: One hundred seventy-five adult patients coming for fasting lipid profile were included; their non-fasting samples were taken on the next day...
December 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28035343/effects-of-different-degrees-of-insulin-resistance-on-endothelial-function-in%C3%A2-obese%C3%A2-adults-undergoing-alternate-day%C3%A2-fasting
#19
Kristin K Hoddy, Surabhi Bhutani, Shane A Phillips, Krista A Varady
BACKGROUND: Obesity can have deleterious effects on insulin sensitivity leading to endothelial dysfunction. Whether alternate day fasting (ADF) can ameliorate insulin sensitivity in a way that improves endothelial function remains unknown. OBJECTIVE: This study examined the impact of ADF on endothelium dependent flow mediated dilation (FMD) in obese subjects with different degrees of insulin resistance. METHODS: Obese non-diabetic adults (n = 54) participated in an 8-week ADF protocol (25% energy intake "fast day", alternated with ad libitum intake "feast day")...
October 27, 2016: Nutr Healthy Aging
https://www.readbyqxmd.com/read/28018597/associations-between-unhealthy-dieting-behaviors-and-tobacco-use-among-adolescents
#20
Megan E Sutter, Aashir Nasim, Susan Veldheer, Caroline O Cobb
BACKGROUND: Cigarette smoking is an important risk factor for unhealthy dieting behaviors (UDBs) in youth. The role of alternative tobacco products and UDB engagement has yet to be examined empirically despite concerning trends in use. This study aimed to examine UDB prevalence in a U.S. geographic region-specific adolescent sample and associations with a variety of tobacco use behaviors and perceptions. METHODS: Weighted data from the 2013 Virginia Youth Survey were analyzed (n = 6903)...
2016: Journal of Eating Disorders
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