keyword
https://read.qxmd.com/read/38512627/imaging-and-prognostic-characterization-of-fat-containing-hepatocellular-carcinoma-subtypes
#1
JOURNAL ARTICLE
Alexandre Faure, Marco Dioguardi Burgio, Roberto Cannella, Riccardo Sartoris, Mohamed Bouattour, Christian Hobeika, Francois Cauchy, Loïc Trapani, Aurélie Beaufrère, Valérie Vilgrain, Maxime Ronot
PURPOSE: Steatohepatitic hepatocellular carcinoma (SH-HCC) is characterized by intratumoral fat with > 50% inflammatory changes. However, intratumoral fat (with or without inflammation) can also be found in not-otherwise specified HCC (NOS-HCC). We compared the imaging features and outcome of resected HCC containing fat on pathology including SH-HCC (> 50% steatohepatitic component), NOS-HCC with < 50% steatohepatitic component (SH-NOS-HCC), and fatty NOS-HCC (no steatohepatitic component)...
March 21, 2024: La Radiologia Medica
https://read.qxmd.com/read/38365352/role-of-intravoxel-incoherent-motion-ivim-imaging-in-response-assessment-of-hepatocellular-carcinoma-after-transarterial-chemoembolization-tace-a-prospective-study
#2
JOURNAL ARTICLE
M Reddy Bursapalle, J Valakkadaa, A Ayappan
INTRODUCTION: Response evaluation of hepatocellular carcinoma (HCC) currently is based on arterial phase enhancement which doesn't take into microstructural changes in the tumor after trans-arterial chemoembolization (TACE). AIM: This prospective study was conducted to assess the feasibility and efficacy of intravascular incoherent motion imaging (IVIM) in response evaluation of HCC after TACE. 39 cirrhotic patients with 48 HCC underwent MR imaging 1 week within and 6weeks after TACE...
2024: Radiología
https://read.qxmd.com/read/38064309/editorial-for-comparative-performance-of-2018-li-rads-versus-modified-lirads-mli-rads-an-individual-participant-data-meta-analysis
#3
EDITORIAL
Yasuo Takehara, Ryota Hyodo
No abstract text is available yet for this article.
December 8, 2023: Journal of Magnetic Resonance Imaging: JMRI
https://read.qxmd.com/read/38038346/comparative-performance-of-2018-li-rads-versus-modified-lirads-mli-rads-an-individual-participant-data-meta-analysis
#4
JOURNAL ARTICLE
Stacy M Goins, Hanyu Jiang, Christian B van der Pol, Jean-Paul Salameh, Eric Lam, Robert G Adamo, Matthew D F McInnes, Andreu F Costa, Christopher Clarke, Sang Hyun Choi, Tyler J Fraum, Daniel R Ludwig, Bin Song, Ijin Joo, Andrea S Kierans, So Yeon Kim, Heejin Kwon, Joanna Podgórska, Grzegorz Rosiak, Mustafa R Bashir
BACKGROUND: LI-RADS version 2018 (v2018) is used for non-invasive diagnosis of hepatocellular carcinoma (HCC). A recently proposed modification (known as mLI-RADS) demonstrated improved sensitivity while maintaining specificity and positive predictive value (PPV) of LI-RADS category 5 (definite HCC) for HCC. However, mLI-RADS requires multicenter validation. PURPOSE: To evaluate the performance of v2018 and mLI-RADS for liver lesions in a large, heterogeneous, multi-national cohort of patients at risk for HCC...
December 1, 2023: Journal of Magnetic Resonance Imaging: JMRI
https://read.qxmd.com/read/37725492/quantification-of-hepatocellular-carcinoma-vascular-dynamics-with-contrast-enhanced-ultrasound-for-li-rads-implementation
#5
JOURNAL ARTICLE
Connor Krolak, Manjiri Dighe, Alicia Clark, Marissa Shumaker, Raymond Yeung, Richard G Barr, Yuko Kono, Michalakis Averkiou
OBJECTIVE: The aim of this study is to describe a comprehensive contrast-enhanced ultrasound (CEUS) imaging protocol and analysis method to implement CEUS LI-RADS (Liver Imaging Reporting and Data System) in a quantifiable manner. The methods that are validated with a prospective single-center study aim to simplify CEUS LI-RADS evaluation, remove observer bias, and potentially improve the sensitivity of CEUS LI-RADS. MATERIALS AND METHODS: This prospective single-center study enrolled patients with hepatocellular carcinoma (April 2021-June 2022; N = 31; mean age ± SD, 67 ± 6 years; 24 men/7 women)...
April 1, 2024: Investigative Radiology
https://read.qxmd.com/read/37723439/surveillance-and-treatment-of-primary-hepatocellular-carcinoma-aka-stop-hcc-protocol-for-a-prospective-cohort-study-of-high-risk-patients-for-hcc-using-galad-score
#6
JOURNAL ARTICLE
Thai Ngoc Truong, Trang Ngoc Doan Pham, Long Bao Hoang, Van Thi Nguyen, Hang Viet Dao, Diem Vu Bich Dao, Saleh Alessy, Hien Ba Pham, Thuy Thi Thu Pham, Linh Duc Duy Nguyen, Khue Nguyen, Faisal Abaalkhail, Mohammed Manal, Mohammad Mawardi, May AlZahrani, Khalid Alswat, Hamdan Alghamdi, Faisal M Sanai, Mohammed Amir Siddiqui, Nam Hai Nguyen, Dhananjay Vaidya, Hai Thanh Phan, Philip J Johnson, Saleh A Alqahtani, Doan Y Dao
BACKGROUND: Vietnam and Saudi Arabia have high disease burden of primary hepatocellular carcinoma (HCC). Early detection in asymptomatic patients at risk for HCC is a strategy to improve survival outcomes in HCC management. GALAD score, a serum-based panel, has demonstrated promising clinical utility in HCC management. However, in order to ascertain its potential role in the surveillance of the early detection of HCC, GALAD needs to be validated prospectively for clinical surveillance of HCC (i...
September 18, 2023: BMC Cancer
https://read.qxmd.com/read/36195953/comparison-of-international-guidelines-for-diagnosis-of-hepatocellular-carcinoma-and-implications-for-transplant-allocation-in-liver-transplantation-candidates-with-gadoxetic-acid-enhanced-liver-mri-versus-contrast-enhanced-ct-a-prospective-study-with-liver
#7
JOURNAL ARTICLE
Devang Odedra, Ali Babaei Jandaghi, Rajesh Bhayana, Khaled Y Elbanna, Osvaldo Espin-Garcia, Sandra E Fischer, Anand Ghanekar, Gonzalo Sapisochin, Kartik S Jhaveri
OBJECTIVES: To compare the diagnostic performance of international hepatocellular carcinoma (HCC) guidelines with gadoxetic acid-enhanced MRI (EOB-MRI) and contrast-enhanced Computed tomography (CECT) and their impact on liver transplant (LT) allocation in cirrhotic patients with explant histopathology correlation. METHODS: In this prospective single-centre ethics-approved study, 101 cirrhotic patients were consecutively enrolled with informed consent from the pre-LT clinic...
October 4, 2022: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://read.qxmd.com/read/35814502/the-course-of-lirads-3-and-4-hepatic-abnormalities-as-correlated-with-explant-pathology-a-single-center-experience
#8
JOURNAL ARTICLE
Panita Mettikanont, Anita Kalluri, Therese Bittermann, Neil Phillips, Bao-Li Loza, Mark Rosen, Evan Siegelman, Emma Furth, Peter Abt, Kim Olthoff, Abraham Shaked, Maarouf Hoteit, K Rajender Reddy
Background and aims: The Liver Reporting and Data System (LI-RADS) is the standard classification of imaging findings of hepatic abnormalities for hepatocellular carcinoma (HCC) surveillance. We aimed to study the course of LI-RADS 3 and 4 (LR-3 and LR-4) abnormalities through correlations with explant pathology. Methods: A single center retrospective study of liver transplant recipients between January 2016 and September 2019 with HCC on explant pathology was conducted...
July 2022: Journal of Clinical and Experimental Hepatology
https://read.qxmd.com/read/35018797/editorial-comment-factors-impacting-ultrasound-li-rads-visualization-scores-optimizing-future-quality-assurance-and-standards
#9
COMMENT
Sarah Bastawrous
No abstract text is available yet for this article.
June 2022: AJR. American Journal of Roentgenology
https://read.qxmd.com/read/34820032/optimizing-diagnostic-imaging-data-using-li-rads-and-the-likert-scale-in-patients-with-hepatocellular-carcinoma
#10
JOURNAL ARTICLE
Kholoud Morad, Amr F Moustafa, Amal M Refaat, Ahmed AbdEllatif, Mohammed S ElAzab
PURPOSE: The study aimed to compare the diagnostic performance of the Liver Imaging Reporting and Data System (LI-RADS), which incorporates fixed criteria, and the Likert scale (LS), which mainly depends on an overall impression in liver lesion diagnosis. MATERIAL AND METHODS: Diagnostic data of 110 hepatic nodules in 103 high-risk patients for hepatocellular carcinoma (HCC) were included. Data including diameter, arterial hyperenhancement, washout, and capsule were reviewed by 2 readers using LI-RADS and LS (range, score 1-5)...
2021: Polish Journal of Radiology
https://read.qxmd.com/read/34540956/novel-model-combining-contrast-enhanced-ultrasound-with-serology-predicts-hepatocellular-carcinoma-recurrence-after-hepatectomy
#11
JOURNAL ARTICLE
Hai-Bin Tu, Li-Hong Chen, Yu-Jie Huang, Si-Yi Feng, Jian-Ling Lin, Yong-Yi Zeng
BACKGROUND: Surgery is the primary curative option in patients with hepatocellular carcinoma (HCC). However, recurrence within 2 years is observed in 30%-50% of patients, being a major cause of mortality. AIM: To construct and verify a non-invasive prediction model combining contrast-enhanced ultrasound (CEUS) with serology biomarkers to predict the early recurrence of HCC. METHODS: Records of 744 consecutive patients undergoing first-line curative surgery for HCC in one institution from 2016-2018 were reviewed, and 292 local patients were selected for analysis...
August 26, 2021: World Journal of Clinical Cases
https://read.qxmd.com/read/34130851/imaging-after-locoregional-therapy-for-hepatocellular-carcinoma-with-emphasis-on-lirads-treatment-response-assessment-criteria
#12
JOURNAL ARTICLE
Gitanjali Bajaj, Karthik Sundaram, Kedar Jambhekar, Roopa Ram
The Liver Imaging Reporting and Data System (LI-RADS) is a set of algorithms designed to provide a standardized, comprehensive framework for the interpretation of surveillance and diagnostic imaging in patients at high risk for hepatocellular carcinoma. LI-RADS is the result of a multidisciplinary collaboration between radiologists, hepatologists, hepatobiliary surgeons and pathologists and has recently been incorporated into the practice guidelines for the American Association for the Study of Liver Diseases (AASLD) and made congruent with the Organ Procurement and Transplantation Network (OPTN) criteria...
August 2021: Seminars in Ultrasound, CT, and MR
https://read.qxmd.com/read/34130846/imaging-after-locoregional-therapy-for-hepatocellular-carcinoma-with-emphasis-on-lirads-treatment-response-assessment-criteria
#13
REVIEW
Gitanjali Bajaj, Karthik Sundaram, Kedar Jambhekar, Roopa Ram
Radiologists play an essential role in assessing hepatocellular carcinoma treatment response and help guide further clinical management of patients. Interpretation of treatment response after locoregional therapy is challenging. The post-treatment imaging findings vary and depend on the type of treatment, the degree of treatment response, time interval after treatment and several other factors. Given the widespread use of local-regional therapies, understanding the appearance of treated lesions has become crucial to allow for a more accurate interpretation of post-treatment imaging...
August 2021: Seminars in Ultrasound, CT, and MR
https://read.qxmd.com/read/33180163/virtual-monoenergetic-images-from-spectral-detector-computed-tomography-facilitate-washout-assessment-in-arterially-hyper-enhancing-liver-lesions
#14
JOURNAL ARTICLE
R P Reimer, N Große Hokamp, A Fehrmann Efferoth, A Krauskopf, D Zopfs, J R Kröger, T Persigehl, D Maintz, A C Bunck
OBJECTIVES: To investigate whether the increased soft tissue contrast of virtual monoenergetic images (VMIs) obtained from a spectral detector computed tomography (SDCT) system improves washout assessment of arterially hyper-enhancing liver lesions. METHODS: Fifty-nine arterially hyper-enhancing lesions in 31 patients (age 65 ± 9 years, M/W 20/11) were included in this IRB-approved study. All patients underwent multi-phase SDCT for HCC screening. MRI, CEUS or biopsy within 3 months served as standard of reference to classify lesions as LiRADS 3 or 4/5...
May 2021: European Radiology
https://read.qxmd.com/read/32717752/contrast-enhanced-ultrasound-algorithms-ceus-lirads-esculap-for-the-noninvasive-diagnosis-of-hepatocellular-carcinoma-a-prospective-multicenter-degum-study
#15
JOURNAL ARTICLE
Barbara Schellhaas, Thomas Bernatik, Wolfram Bohle, Fanny Borowitzka, Johannes Chang, Christoph F Dietrich, Klaus Dirks, Robert Donoval, Kristine Drube, Mireen Friedrich-Rust, Christine Gall, Fleur Gittinger, Martin Gutermann, Mark Martin Haenle, Alexandra von Herbay, Chau Hong Ho, Rico Hochdoerffer, Tatjana Hoffmann, Matthias Hüttig, Christopher Janson, Ernst-Michael Jung, Norbert Jung, Thomas Karlas, Christoph Klinger, Adam Kornmehl, Wolfgang Kratzer, Sebastian Krug, Georg Kunze, Jens Leitlein, Alexander Link, Christian Lottspeich, Aldo Marano, Martin Mauch, Lukas Moleda, Albrecht Neesse, Golo Petzold, Andrej Potthoff, Michael Praktiknjo, Klaus-Dieter Rösner, Stefan Schanz, Michael Schultheiß, Visvakanth Sivanathan, Joachim Stock, Thomas Thomsen, Johanna Vogelpohl, Christoph Vogt, Siegfried Wagner, Christiane Wiegard, Isabel Wiesinger, Uwe Will, Matthias Ziesch, Patrick Zimmermann, Deike Strobel
No abstract text is available yet for this article.
April 2021: Ultraschall in der Medizin
https://read.qxmd.com/read/32663881/contrast-enhanced-ultrasound-algorithms-ceus-lirads-esculap-for-the-noninvasive-diagnosis-of-hepatocellular-carcinoma-a-prospective-multicenter-degum-study
#16
MULTICENTER STUDY
Barbara Schellhaas, Thomas Bernatik, Wolfram Bohle, Fanny Borowitzka, Johannes Chang, Christoph F Dietrich, Klaus Dirks, Robert Donoval, Kristine Drube, Mireen Friedrich-Rust, Christine Gall, Fleur Gittinger, Martin Gutermann, Mark Martin Haenle, Alexandra von Herbay, Chau Hong Ho, Rico Hochdoerffer, Tatjana Hoffmann, Matthias Hüttig, Christopher Janson, Ernst-Michael Jung, Norbert Jung, Thomas Karlas, Christoph Klinger, Adam Kornmehl, Wolfgang Kratzer, Sebastian Krug, Georg Kunze, Jens Leitlein, Alexander Link, Christian Lottspeich, Aldo Marano, Martin Mauch, Lukas Moleda, Albrecht Neesse, Golo Petzold, Andrej Potthoff, Michael Praktiknjo, Klaus-Dieter Rösner, Stefan Schanz, Michael Schultheiß, Visvakanth Sivanathan, Joachim Stock, Thomas Thomsen, Johanna Vogelpohl, Christoph Vogt, Siegfried Wagner, Christiane Wiegard, Isabel Wiesinger, Uwe Will, Matthias Ziesch, Patrick Zimmermann, Deike Strobel
BACKGROUND:  This prospective multicenter study funded by the DEGUM assesses the diagnostic accuracy of standardized contrast-enhanced ultrasound (CEUS) for the noninvasive diagnosis of hepatocellular carcinoma (HCC) in high-risk patients. METHODS:  Patients at high risk for HCC with a histologically proven focal liver lesion on B-mode ultrasound were recruited prospectively in a multicenter approach. Clinical and imaging data were entered via online entry forms...
April 2021: Ultraschall in der Medizin
https://read.qxmd.com/read/32643777/contrast-enhanced-ultrasound-liver-imaging-reporting-and-data-system-in-diagnosing-hepatocellular-carcinoma-diagnostic-performance-and-interobserver-agreement
#17
JOURNAL ARTICLE
Hang Zhou, Chao Zhang, Linyao Du, Jiapeng Jiang, Qing Zhao, Jiawei Sun, Qunying Li, Ming Wan, Xiaolei Wang, Xiujuan Hou, Qing Wen, Yajing Liu, Xianli Zhou, Pintong Huang
OBJECTIVES:  To determine the diagnostic performance and inter-reader agreement of the contrast-enhanced ultrasound liver imaging reporting and data system (CEUS-LI-RADS) for diagnosing hepatocellular carcinoma (HCC) in high-risk patients. METHODS:  In this prospective study, CEUS-LI-RADS categories (LR-5 for predicting HCC) were assigned by six blinded readers and compared to the definitive HCC diagnosis in patients with liver cirrhosis per the 2017 China Liver Cancer Guidelines (CLCG)...
July 8, 2020: Ultraschall in der Medizin
https://read.qxmd.com/read/32610844/role-of-mri-in-evaluation-of-spectrum-of-liver-lesions-in-cirrhotic-patients
#18
JOURNAL ARTICLE
Anagha Joshi, Sukhada Kulkarni, Ankita Shah
MRI provides better intrinsic soft-tissue contrast with more enhanced depiction of even subtly different tissue properties making lesion evaluation easy. Faster sequences which capture arterial sequences better, lack of ionizing radiation and simultaneous evaluation of background liver parenchyma and the liver lesions are additional advantages of using MRI as the imaging technique of choice. Comprehensive liver imaging using MRI now includes T1, T2-weighted imaging and in- and opposed-phase, in addition to dynamic post-contrast imaging with proper breath holding techniques...
April 2020: Journal of the Association of Physicians of India
https://read.qxmd.com/read/32595103/absence-of-impact-of-direct-acting-antivirals-for-hepatitis-c-virus-on-recurrent-hepatocellular-carcinoma-tumor-growth-in-the-afef-anrs-co22-hepather-cohort
#19
JOURNAL ARTICLE
Anais Vallet-Pichard, Jean-Michel Correas, Celine Dorival, Fabien Zoulim, Albert Tran, Marc Bourlière, Paul Calès, Dominique Guyader, Jean-Pierre Bronowicki, Dominique Larrey, Christophe Hezode, Veronique Loustaud-Ratti, Jerome Gournay, Victor de Ledinghen, Tarik Asselah, Nathalie Ganne, Sophie Metivier, Olivier Chazouillères, Vincent Leroy, Isabelle Rosa, Didier Samuel, Philippe Mathurin, Carole Cagnot, Helene Fontaine, Fabrice Carrat, Stanislas Pol
BACKGROUND: Although it has now been excluded that direct-acting antivirals (DAA) are associated with a significant risk of hepatocellular carcinoma (HCC) in HCV-infected patients, a possible effect of DAA on tumor growth is still a subject of debate. We performed a blind comparison of the kinetics of HCC recurrence in patients after HCV treatment with or without DAA to evaluate the potential aggressiveness of HCC after DAA treatment. BASIC PROCEDURES: Thirty-nine HCV-infected patients from the AFEF/ANRS CO22 Hepather cohort who experienced HCC recurrence after so-called curative treatment were evaluated...
June 25, 2020: Clinics and Research in Hepatology and Gastroenterology
https://read.qxmd.com/read/32463393/major-and-ancillary-features-according-to-li-rads-in-the-assessment-of-combined-hepatocellular-cholangiocarcinoma
#20
JOURNAL ARTICLE
Vincenza Granata, Roberta Fusco, Sergio Venanzio Setola, Fabio Sandomenico, Maria Luisa Barretta, Andrea Belli, Raffaele Palaia, Fabiana Tatangelo, Roberta Grassi, Francesco Izzo, Antonella Petrillo
Background The aim of the study was to investigate the performance of the Liver Imaging Reporting and Data System (LI-RADS) v2018 for combined hepatocellular-cholangiocarcinoma (cHCC-CCA) identifying the features that allow an accurate characterization. Patients and methods Sixty-two patients (median age, 63 years; range, 38-80 years), with pre-surgical biopsy diagnosis of hepatocellular carcinoma (HCC) that underwent hepatic resection, comprised our retrospective study. All patients were subject to multidetector computed tomography (MDCT); 23 patients underwent to magnetic resonance (MR) study...
May 28, 2020: Radiology and Oncology
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