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https://www.readbyqxmd.com/read/28738126/comparing-plasma-phospho-tau-total-tau-and-phospho-tau-total-tau-ratio-as-acute-and-chronic-traumatic-brain-injury-biomarkers
#1
Richard Rubenstein, Binggong Chang, John K Yue, Allen Chiu, Ethan A Winkler, Ava M Puccio, Ramon Diaz-Arrastia, Esther L Yuh, Pratik Mukherjee, Alex B Valadka, Wayne A Gordon, David O Okonkwo, Peter Davies, Sanjeev Agarwal, Fan Lin, George Sarkis, Hamad Yadikar, Zhihui Yang, Geoffrey T Manley, Kevin K W Wang, Shelly R Cooper, Kristen Dams-O'Connor, Allison J Borrasso, Tomoo Inoue, Andrew I R Maas, David K Menon, David M Schnyer, Mary J Vassar
Importance: Annually in the United States, at least 3.5 million people seek medical attention for traumatic brain injury (TBI). The development of therapies for TBI is limited by the absence of diagnostic and prognostic biomarkers. Microtubule-associated protein tau is an axonal phosphoprotein. To date, the presence of the hypophosphorylated tau protein (P-tau) in plasma from patients with acute TBI and chronic TBI has not been investigated. Objective: To examine the associations between plasma P-tau and total-tau (T-tau) levels and injury presence, severity, type of pathoanatomic lesion (neuroimaging), and patient outcomes in acute and chronic TBI...
July 24, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28735848/the-outcomes-and-affecting-factors-after-arthroscopic-isolated-subscapularis-tendon-repair
#2
Yong Girl Rhee, Yeong Seok Lee, Yong Bok Park, Jung Youn Kim, Kwang Joon Han, Jae Chul Yoo
BACKGROUND: This study evaluated clinical outcomes for isolated subscapularis tendon tears treated by arthroscopic repair, the factors affecting clinical outcomes, and changes in tendon structural integrity using magnetic resonance imaging. METHODS: Between 2005 and 2013, 45 patients with isolated subscapularis tendon tears were enrolled from two institutions. Clinical outcomes were assessed using the pain visual analog scale, American Shoulder and Elbow Surgeons, and Simple Shoulder Test scores...
July 20, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28735671/choroid-plexus-cyst-in-a-neonatal-burmeister-s-porpoise-phocoena-spinipinnis
#3
J Díaz-Delgado, K R Groch, M W Wiegand, E R Secchi, R Réssio, F C C Natália, J L Catão-Dias
Neuroectodermal developmental anomalies are reported rarely in cetaceans and central nervous system cysts are not described. We describe the gross, microscopical, histochemical and immunohistochemical features of a neuraxial myelencephalic cyst in a stranded neonatal Burmeister's porpoise (Phocoena spinipinnis). Grossly, a subdural, extra-axial, well-demarcated, yellow fluid-filled cystic structure (1.9 × 1.6 × 1 cm) expanded the left foramen of Luschka, the left caudolateral cerebellar recess and the left cranioventral myelencephalon...
July 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28712901/henry-ii-of-france-1519-1559-and-his-death-from-meningoencephalitis-following-a-cranial-trauma
#4
REVIEW
Konstantinos Markatos, Marianna Karamanou, Konstantina Arkoudi, Georgios Androutsos
The purpose of this historical review is to summarize the most significant theories on the cause of death of King Henry II of France (1519-1559) and the circumstances under which it occurred. Although the testimonies are inconclusive and vague, post mortem analysis showed that the cause of death of the King was meningoencephalitis, caused by haematoma of cerebral contusion, with effusion in the cerebral laminae, in its surrounding tissue initiated from a periorbital fracture.
July 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28710893/fracture-of-the-medial-intercondylar-eminence-of-the-tibia-in-horses-treated-by-arthroscopic-fragment-removal-21-horses
#5
L M Rubio-Martínez, R Redding, B Bladon, H Wilderjans, R J Payne, C Tessier, O Geffroy, R Parker, C Bell, F A Collingwood
BACKGROUND: Fractures of the medial intercondylar eminence of the tibia (MICET) are scarcely reported in horses. OBJECTIVES: To report the clinical and diagnostic findings, surgical treatment and outcome in a series of horses presented with MICET fracture and treated with arthroscopic fragment removal. STUDY DESIGN: Multi-centre retrospective case series. METHODS: Case records of horses diagnosed with MICET fractures that had undergone surgical treatment were reviewed...
July 15, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28706764/neuroradiological-endovascular-intervention-for-diplopia-in-a-case-of-aneurysmal-aberrant-regeneration-of-the-third-nerve
#6
Anupam C A Rao, Saumil A Shah, Benjamin W C Sim, Steven T H Yun, Neeranjali S Jain, Yashar Kalani, Ian C Francis
Aberrant regeneration of the third nerve occurs as a result of synkinetic 'miswiring' of the third nerve following its injury, such as in third cranial nerve palsy due to tumor, trauma, or aneurysm. The case presented is an elderly woman with new vertical diplopia, which led to a diagnosis of a third cranial nerve palsy, thought to be caused by a 5 mm blister aneurysm of the posterior communicating artery. However, neuro-ophthalmological evaluation diagnosed aberrant regeneration of the third nerve, with the cause of her new vertical diplopia being an ipsilateral fourth nerve palsy...
June 12, 2017: Curēus
https://www.readbyqxmd.com/read/28702053/etiology-of-hypopituitarism-in-adult-patients-the-experience-of-a-single-center-database-in-the-serbian-population
#7
M Doknić, S Pekić, D Miljić, I Soldatović, V Popović, M Stojanović, M Petakov
There are only a few published studies related to the population-based etiology of hypopituitarism. New risks for developing hypopituitarism have been recognized in the last 10 years. Aim. To present data regarding the etiology of hypopituitarism collected in a tertiary center over the last decade. This is a cross-sectional database study. Patients and Methods. We included 512 patients (pts) with hypopituitarism, with a mean age of 45.9 ± 1.7 yrs (range: 18-82; male: 57.9%). Results. Nonfunctional pituitary adenomas were presented in 205 pts (40...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28692515/criteria-for-performing-cranial-computed-tomography-for-chinese-patients-with-mild-traumatic-brain-injury-canadian-computed-tomography-head-rule-or-new-orleans-criteria
#8
Xiao-Feng Yang, Yuan-Yuan Meng, Liang Wen, Hao Wang
Computed tomography (CT) provides the primary diagnostic evidence for traumatic brain injury (TBI), but few positive traumatic findings are discovered in patients with mild TBI. In China, there are no existing criteria for selecting patients with mild TBI to undergo CT, and almost all of these patients undergo cranial CT in the emergency department. This retrospective study was performed to evaluate the necessity of cranial CT among patients with mild TBI, as well as the feasibility of 2 popular criteria (Canadian CT head rule [CCHR] and New Orleans Criteria [NOC]) in China...
July 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28682827/anesthesia-for-minimally-invasive-neurosurgery
#9
Hemanshu Prabhakar, Charu Mahajan, Indu Kapoor
PURPOSE OF REVIEW: With an ultimate aim of improving patients overall outcome and satisfaction, minimally invasive surgical approach is becoming more of a norm. The related anesthetic evidence has not expanded at the same rate as surgical and technological advancement. This article reviews the recent evidence on anesthesia and perioperative concerns for patients undergoing minimally invasive neurosurgery. RECENT FINDINGS: Minimally invasive cranial and spinal surgeries have been made possible only by vast technological development...
July 5, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28665242/changes-in-use-of-cervical-spine-magnetic-resonance-imaging-for-pediatric-patients-with-nonaccidental-trauma
#10
Ahyuda Oh, Michael Sawvel, David Heaner, Amina Bhatia, Andrew Reisner, R Shane Tubbs, Joshua J Chern
OBJECTIVE Past studies have suggested correlations between abusive head trauma and concurrent cervical spine (c-spine) injury. Accordingly, c-spine MRI (cMRI) has been increasingly used in radiographic assessments. This study aimed to determine trends in cMRI use and treatment, and outcomes related to c-spine injury in children with nonaccidental trauma (NAT). METHODS A total of 503 patients with NAT who were treated between 2009 and 2014 at a single pediatric health care system were identified from a prospectively maintained database...
June 30, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28662892/glibenclamide-pretreatment-protects-against-chronic-memory-dysfunction-and-glial-activation-in-rat-cranial-blast-traumatic-brain-injury
#11
Jesse A Stokum, Kaspar Keledjian, Erik Hayman, Jason K Karimy, Adam Pampori, Ziyan Imran, Seung Kyoon Woo, Volodymyr Gerzanich, J Marc Simard
Blast traumatic brain injury (bTBI) affects both military and civilian populations, and often results in chronic deficits in cognition and memory. Chronic glial activation after bTBI has been linked with cognitive decline. Pharmacological inhibition of sulfonylurea receptor 1 (SUR1) with glibenclamide was shown previously to reduce glial activation and improve cognition in contusive models of CNS trauma, but has not been examined in bTBI. We postulated that glibenclamide would reduce chronic glial activation and improve long-term memory function after bTBI...
June 27, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28645605/emergency-reoperations-in-cranial-neurosurgery
#12
Borys M Kwinta, Roger M Krzyżewski, Kornelia M Kliś, Paulina Donicz, Małgorzata Gackowska, Jarosław Polak, Krzysztof Stachura, Marek Moskała
BACKGROUND: Complications after neurosurgical procedures which lead to reoperation are associated with poor outcome and economic costs. Therefore the aim of our study was to establish predictors of reoperation due to complications after cranial neurosurgery. METHODS: We retrospectively analysed 875 patients who underwent a cranial neurosurgical procedure. We used univariate and multivariate logistic regression analysis to determine the possible predictors of reoperation...
June 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28645601/a-cranial-trauma-was-the-cause-of-death-of-charles-viii-of-france-1470-1498
#13
REVIEW
Konstantinos Markatos, Marianna Karamanou, Konstantina Arkoudi, Apostolia Konstantinidi, Georgios Androutsos
The purpose of this manuscript is to summarize the reign, life and death of Charles VIII of France. Also the authors intend to investigate current views on his cause of death, contradictions and opinions of his biographers. Poisoning, disease and injury are the possible causes of his death but, according to the literature, cranial trauma was the most probable cause of death of the king Charles VIII of France.
June 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28644544/the-frontal-peak-sign-a-potential-new-indication-of-open-approach-in-frontal-sinus-mucoceles-with-posterior-table-erosion-a-retrospective-chart-review-of-thirty-seven-patients
#14
Emilie Béquignon, Jean-Philippe Blancal, Jean-Pierre Guichard, Katell Ruellan, Romain Kania, Elisabeth Sauvaget, Damien Bresson, Philippe Herman, Benjamin Verillaud
To date, most frontal mucoceles are treated endoscopically, provided that there is no major neo-osteogenesis and that the frontal sinus floor is wide enough to provide an adequate working space: the presence of a sinus wall dehiscence is not considered as a contraindication to an endoscopic approach. We report on a series of 37 patients presenting with frontal sinus mucoceles with posterior table erosion. Thirty-three (89.2%) had minimal erosion and/or a limited protrusion of the mucocele within the anterior cranial fossa on CT-scan, and were successfully operated on through an endoscopic approach...
June 23, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28637207/the-use-of-semitranslucent-rubber-pledgets-during-microsurgical-dissection-of-cerebellopontine-angle-tumors-technical-note
#15
Marcus D Mazur, Richard Gurgel, Joel D MacDonald
BACKGROUND AND IMPORTANCE: Dissection of cerebellopontine angle (CPA) tumors that abut or adhere to the brainstem or cranial nerves can be a challenging surgical endeavor. We describe the use of semitranslucent latex rubber pledgets in the tumor-brain interface as a method to improve visualization and protection of vital tissue during microsurgical dissection of CPA masses. The rubber pledgets are fashioned by cutting circular discs out of the cuff portion of talc-free, partially opaque latex gloves...
June 20, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28610768/intracranial-subarachnoid-fat-and-hemorrhage-secondary-to-sacral-fracture-with-spondylopelvic-dissociation
#16
J Carreres Polo, M V Álvarez Martínez, D Sánchez Mateos
We describe a case of fat droplets and blood in the cerebral subarachnoid space secondary in a patient with a complex sacral fracture without associated cranial trauma, a few days after admission. To our knowledge, there is only one published case with similar findings and without any other underlying lesion as cause. We explain the differences in the mechanism of production between this direct fat embolism and brain fat embolism syndrome, which is an intravascular embolism with different radiological appearance...
June 10, 2017: Radiología
https://www.readbyqxmd.com/read/28593627/efficacy-and-safety-of-using-n-butyl-cyanoacrylate-in-fixation-of-cranial-following-trauma-and-other-pathologies
#17
Ahmed Sultan, Abbas Mohamed
Skull Bone fixation following different cranial surgeries is essential and should be rigid, simple and cheap. We describe our technique of cranial fixation using the adhesive cyanoacrylates. MATERIALS AND METHODS: At the end of cranial and intracranial surgeries the craniotomy flap and bone pieces are returned, realigned and fixed using Histoacryl® (N-Butyl Cyanoacrylate) glue. The glue is applied all around the flap in 360 degrees fashion. RESULT: The adhesive material was used in 24 cases after different surgeries involving the calvaria of the skull...
April 30, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28593009/ultrasound-as-point-of-care-in-management-of-polytrauma-and-its-complication
#18
Saverio Latteri, Giulia Malaguarnera, Maurizio Mannino, Antonio Pesce, Giuseppe Currò, Stefania Tamburrini, Mario Scuderi
PURPOSE: Traumatic injuries constitute a major risk for patients in emergency units. Point-of-care ultrasound may be a determinant in reducing the deleterious impact of complications and in prognosis. METHODS: We describe the case of a 28-year-old female who reported cranial trauma, abdominal and thoracic trauma, and suspected bilateral fracture of the femur. RESULTS: Ultrasound was useful for evaluating and monitoring multiple organ failure...
June 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/28555241/prehistoric-massacre-revealed-perimortem-cranial-trauma-from-poto%C3%A4-ani-croatia
#19
Ivor Janković, Jacqueline Balen, James C M Ahern, Zrinka Premužić, Mislav Čavka, Hrvoje Potrebica, Mario Novak
During archaeological rescue excavations carried out in 2007 at Potočani in continental Croatia, a pit containing numerous human skeletal remains (MNI = 41) was discovered. The remains were mostly articulated but also commingled and showed no clear pattern of organization. There were no associated artifacts, just a few pottery fragments probably belonging to the Copper Age Lasinja Culture (c. 4300 to 3950 BCE). Anthropological analyses suggest the presence of individuals of all ages and both sexes with many crania exhibiting various perimortem injuries...
May 30, 2017: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/28553772/prenatal-ultrasound-parameters-in-single-suture-craniosynostosis
#20
Martijn J Cornelissen, Inge Apon, Jacques J N M van der Meulen, Irene A L Groenenberg, Mieke N Kraan-van der Est, Irene M J Mathijssen, Gouke J Bonsel, Titia E Cohen-Overbeek
INTRODUCTION: Although single-suture craniosynostosis is diagnosed sporadically during pregnancy, timely referral is critical for its treatment. Additionally, craniosynostosis leads to increased maternofetal trauma during birth. In the Netherlands, 95% of pregnant women receive a standard ultrasound at around 20 weeks of gestation, potentially an ideal setting for detecting craniosynostosis prenatally. To enhance the prenatal detection of the metopic and the sagittal suture synostosis, we wished to identify new screening parameters...
June 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
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