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https://www.readbyqxmd.com/read/28822441/-clinical-characteristics-of-bronchopulmonary-foregut-malformation
#1
J Liu, J Yin, X Y Liu, Y H Hu, X L Ma, R Zhang, Q Zeng, B P Xu, K L Shen
Objective: To analyze the clinical characteristics, diagnosis and treatment of bronchopulmonary foregut malformation(BPFM). Method: The clinical manifestations, imaging findings and treatment of 8 patients with BPFM were analyzed retrospectively from January 2006 to May 2016 in Beijing Children's Hospital. Result: The age of children varied from 2 months to 7 years and 3 children were male while 5 female. Symptoms showed cough in 6 cases, fever in 4 cases, bucking when intaking of fluids or foods in 3 cases, tachypnea in 1 case, wheezing in 1 case, vomiting in 1 case, haematemesis in 1 case Pulmonary signs were decreased breath sounds in 4 cases, phlegm rale in 3 cases, shortness of breath in 2 cases, wheeze in 1 case, and retraction in 1 case...
August 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28822433/-molecular-biological-and-clinical-characteristics-of-respiratory-syncytial-virus-in-children-with-bronchiolitis
#2
T H Zhang, J Deng, Y Qian, R N Zhu, Y Sun, F Wang, R Tian, L Q Zhao
Objective: To investigate the clinical characteristics of respiratory syncytial virus(RSV)bronchiolitis and molecular biological characteristics of RSV in children in Beijing. Method: In a systematic retrospective study, 2 296 nasopharyngeal aspirates (NPA) were collected from children diagnosed with bronchiolitis from July 2006 to June 2016 for respiratory virus screening using direct immunofluorescence assay (DFA). For specimens positive for RSV, subgroup A or B was confirmed by real time RT-PCR and genotype of RSV was determined by amplifying the full G glycoprotein gene and sequencing...
August 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28820703/assessment-of-u-s-pediatrician-knowledge-of-toxocariasis
#3
Dana M Woodhall, Amanda P Garcia, Craig A Shapiro, Shequenta L Wray, Andi L Shane, Chitra S Mani, Kelly K Stimpert, LeAnne M Fox, Susan P Montgomery
Toxocariasis, one of a group of parasitic diseases known as neglected parasitic infections, is a disease caused by the larvae of two species of Toxocara roundworms, Toxocara canis, from dogs, and less commonly Toxocara cati, from cats. Although most infected individuals are asymptomatic, clinical manifestations may include fever, fatigue, coughing, wheezing, or abdominal pain (visceral toxocariasis) or vision loss, retina damage, or eye inflammation (ocular toxocariasis). To assess U.S. pediatrician knowledge of toxocariasis, we conducted an electronic survey of American Academy of Pediatrics members...
July 31, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28819777/qingkailing-injection-for-treatment-of-children-pneumonia-induced-by-respiratory-syncytial-virus-a-meta-analysis-of-randomized-controlled-trials
#4
Shuai He, Wen-Shi Li, Ya-Jun Luo, Chen-Li Ye, Zhong-Yi Zhang
OBJECTIVE: To evaluate the efficacy and safety of Qingkailing Injection (, QKL) for treatment of children pneumonia caused by respiratory syncytial virus (RSV). METHODS: Randomized clinical trials (RCTs) comparing QKL with ribavirin injection in the treatment of children pneumonia induced by RSV were searched in PubMed, Science Direct, Cochrane Library, Chinese VIP database, CNKI and Wanfang databases from their inception to March 2014. Meta-analyses were performed using RevMan 5...
August 17, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28818544/trends-in-antimicrobial-resistance-in-bloodstream-infection-isolates-at-a-large-urban-hospital-in-malawi-1998-2016-a-surveillance-study
#5
Patrick Musicha, Jennifer E Cornick, Naor Bar-Zeev, Neil French, Clemens Masesa, Brigitte Denis, Neil Kennedy, Jane Mallewa, Melita A Gordon, Chisomo L Msefula, Robert S Heyderman, Dean B Everett, Nicholas A Feasey
BACKGROUND: Bacterial bloodstream infection is a common cause of morbidity and mortality in sub-Saharan Africa, yet few facilities are able to maintain long-term surveillance. The Malawi-Liverpool-Wellcome Trust Clinical Research Programme has done sentinel surveillance of bacteraemia since 1998. We report long-term trends in bloodstream infection and antimicrobial resistance from this surveillance. METHODS: In this surveillance study, we analysed blood cultures that were routinely taken from adult and paediatric patients with fever or suspicion of sepsis admitted to Queen Elizabeth Central Hospital, Blantyre, Malawi from 1998 to 2016...
August 14, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28818475/oseltamivir-use-and-severe-abnormal-behavior-in-japanese-children-and-adolescents-with-influenza-is-a-self-controlled-case-series-study-applicable
#6
Wakaba Fukushima, Kotaro Ozasa, Akihisa Okumura, Masaaki Mori, Mitsuaki Hosoya, Takashi Nakano, Takuya Tanabe, Naoto Yamaguchi, Hiroshi Suzuki, Mitsuru Mori, Hideaki Hatayama, Hirotaka Ochiai, Kyoko Kondo, Kazuya Ito, Satoko Ohfuji, Yosikazu Nakamura, Yoshio Hirota
OBJECTIVE: Since the 1990s, self-controlled designs including self-controlled case series (SCCS) studies have been occasionally used in post-marketing evaluation of drug or vaccine safety. An SCCS study was tentatively applied to evaluate the relationship between oseltamivir use and abnormal behavior Type A (serious abnormal behavior potentially leading to an accident or harm to another person) in influenza patients. METHODS: From the original prospective cohort study with approximately 10,000 Japanese children and adolescents with influenza (aged <18years), 28 subjects (mean age: 7...
August 24, 2017: Vaccine
https://www.readbyqxmd.com/read/28816278/-analysis-of-development-safety-and-efficacy-of-percutaneous-nephrolithotomy-for-management-of-upper-urinary-tract-calculi-in-pediatric-patients
#7
L P Yu, T Xu
OBJECTIVE: To evaluate the development, safety and efficacy of percutaneous nephrolithotomy(PNL) for management of upper urinary tract calculi in pediatric patients. METHODS: In the study, 77 pediatric patients undergoing 87 PNLs through mini or standard tract for upper urinary tract calculi between January 2005 and December 2016 in Peking University People's hospital were reviewed, including 69 renal calculi, 6 upper ureteral calculi, 12 renal and upper ureteral calculi, 35 single calculi, 43 multiple calculi and 9 staghorn calculi...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28813007/the-efficacy-of-bifidobacterium-longum-bori-and-lactobacillus-acidophilus-ad031-probiotic-treatment-in-infants-with-rotavirus-infection
#8
Myeong Soo Park, Bin Kwon, Seockmo Ku, Geun Eog Ji
A total of 57 infants hospitalized with rotavirus disease were included in this study. The children were randomly divided into the study's two treatment groups: three days of the oral administration of (i) a probiotics formula containing both Bifidobacterium longum BORI and Lactobacillus acidophilus AD031 (N = 28); or (ii) a placebo (probiotic-free skim milk, N = 29) and the standard therapy for diarrhea. There were no differences in age, sex, or blood characteristics between the two groups. When the 57 cases completed the protocol, the duration of the patients' diarrhea was significantly shorter in the probiotics group (4...
August 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28811862/allergic-profiles-of-mothers-and-fathers-in-the-japan-environment-and-children-s-study-jecs-a-nationwide-birth-cohort-study
#9
Kiwako Yamamoto-Hanada, Limin Yang, Kazue Ishitsuka, Tadayuki Ayabe, Hidetoshi Mezawa, Mizuho Konishi, Testsuo Shoda, Kenji Matsumoto, Hirohisa Saito, Yukihiro Ohya
BACKGROUND: The Japan Environment and Children's Study (JECS) is a nationwide, multicenter, prospective birth cohort investigation launched by the Ministry of Environment in Japan. The purpose of the JECS is to evaluate the influence of prenatal and postnatal exposures to environmental factors on the postnatal health of the children. In this study, we evaluated the allergic characteristics of parents within the JECS cohort. METHODS: This study covered a wide geographical area and encompassed 15 regional centers...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28810865/cryptic-plasmodium-ovale-concurrent-with-mixed-plasmodium-falciparum-and-plasmodium-malariae-infection-in-two-children-from-central-african-republic
#10
Cynthia Bichara, Philippe Flahaut, Damien Costa, Anne-Lise Bienvenu, Stephane Picot, Gilles Gargala
BACKGROUND: Since several malaria parasite species are usually present in a particular area, co-infections with more than one species of Plasmodium are more likely to occur in humans infected in these areas. In many mixed infections, parasite densities of the cryptic species may be low and often not recognized in clinical practice. CASE PRESENTATION: Two children (3 and 6 years old) adopted recently from Central African Republic were admitted to hospital because of intermittent fever...
August 15, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28810839/relationships-between-sickle-cell-trait-malaria-and-educational-outcomes-in-tanzania
#11
Kevin Croke, Deus S Ishengoma, Filbert Francis, Julie Makani, Mathias L Kamugisha, John Lusingu, Martha Lemnge, Horacio Larreguy, Günther Fink, Bruno P Mmbando
BACKGROUND: Sickle Cell Trait (SCT) has been shown to be protective against malaria. A growing literature suggests that malaria exposure can reduce educational attainment. This study assessed the relationship and interactions between malaria, SCT and educational attainment in north-eastern Tanzania. METHODS: Seven hundred sixty seven children were selected from a list of individuals screened for SCT. Febrile illness and malaria incidence were monitored from January 2006 to December 2013 by community health workers...
August 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28807954/acetylsalicylic-acid-for-children-with-kawasaki-disease
#12
Teeranai Sakulchit, Susanne M Benseler, Ran D Goldman
Question A 7-year-old child in my office was recently discharged from the hospital after receiving intravenous immunoglobulin for Kawasaki disease. Should I continue treatment with acetylsalicylic acid (ASA), and if so, what is the appropriate dose? Answer The role of ASA for Kawasaki disease during the acute febrile phase has recently been called into question. According to several studies, ASA might reduce the duration of fever but it does not appear to directly reduce the incidence of coronary artery complications...
August 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28806976/quantitative-detection-of-human-malawi-polyomavirus-in-nasopharyngeal-aspirates-sera-and-feces-in-beijing-china-using-real-time-taqman-based-pcr
#13
Fen-Lian Ma, Dan-di Li, Tian-Li Wei, Jin-Song Li, Li-Shu Zheng
BACKGROUND: Human Malawi polyomavirus (MWPyV) was discovered in 2012, but its prevalence and clinical characteristics are largely unknown. METHODS: We used real-time TaqMan-based PCR to detect MWPyV in the feces (n = 174) of children with diarrhea, nasopharyngeal aspirates (n = 887) from children with respiratory infections, and sera (n = 200) from healthy adults, and analyzed its clinical characteristics statistically. All the MWPyV-positive specimens were also screened for other common respiratory viruses...
August 14, 2017: Virology Journal
https://www.readbyqxmd.com/read/28806629/aseptic-meningitis-in-adults-and-children-diagnostic-and-management-challenges
#14
Bhavarth Shukla, Elizabeth A Aguilera, Lucrecia Salazar, Susan H Wootton, Quanhathai Kaewpoowat, Rodrigo Hasbun
BACKGROUND: Aseptic meningitis represents a common diagnostic and management dilemma to clinicians. OBJECTIVES: To compare the clinical epidemiology, diagnostic evaluations, management, and outcomes between adults and children with aseptic meningitis. STUDY DESIGN: We conducted a retrospective study from January 2005 through September 2010 at 9 Memorial Hermann Hospitals in Houston, TX. Patients age≥2months who presented with community-acquired aseptic meningitis with a CSF white blood cell count >5cells/mm(3) and a negative Gram stain and cultures were enrolled...
August 4, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28803641/the-assessment-of-risk-factors-for-febrile-seizures-in-children
#15
Krystyna Gontko-Romanowska, Zbigniew Żaba, Paweł Panieński, Barbara Steinborn, Michał Szemień, Magdalena Łukasik-Głębocka, Krystian Ratajczak, Adrian Chrobak, Joanna Mitkowska, Jacek Górny
OBJECTIVE: The aim of the paper was to assess the risk factors of febrile seizures in children. METHODS: The paper presents an analysis of a group of 176 children aged 6 months to 5 years who were admitted to A&E because of febrile seizures. RESULTS: The analysed group of 176 children comprised 61.96% boys and 38.07% girls, and the average age equalled 23 months. Family history was significant in 9.66% of patients. A statistically significant difference was noticed between insignificant family history and the incidence of febrile seizures...
July 31, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28802757/the-typhoid-vaccine-acceleration-consortium-tyvac-vaccine-effectiveness-study-designs-accelerating-the-introduction-of-typhoid-conjugate-vaccines-and-reducing-the-global-burden-of-enteric-fever-report-from-a-meeting-held-on-26-27-october-2016-oxford-uk
#16
James E Meiring, Malick Gibani
Typhoid fever is estimated to cause between 11.9-26.9 million infections globally each year with 129,000-216,510 deaths. Access to improved water sources have reduced disease incidence in parts of the world but the use of efficacious vaccines is seen as an important public health tool for countries with a high disease burden. A new generation of Vi typhoid conjugate vaccines (TCVs), licensed for use in young children and expected to provide longer lasting protection than previous vaccines, are now available...
August 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28801155/vaccinations-in-the-first-year-of-life-and-risk-of-atopic-disease-results-from-the-kiggs-study
#17
Martin Schlaud, Roma Schmitz, Christina Poethko-Müller, Ronny Kuhnert
BACKGROUND: The study focused on the question of whether and - if so - to what direction and extent immunisations in the 1st year may be associated with the risk of being diagnosed with atopic diseases after the 1st year of life. METHODS: Data from the German Health Interview and Examination Survey for Children and Adolescents (KiGGS, 2003-2006) were analysed. For analyses of potential associations between vaccination status and risk of hay fever, atopic dermatitis or asthma, sample sizes of 15254, 14297, and 15262, respectively, were available...
August 8, 2017: Vaccine
https://www.readbyqxmd.com/read/28800058/effectiveness-of-mifamurtide-in-addition-to-standard-chemotherapy-for-high-grade-osteosarcoma-a-systematic-review
#18
Rincy Jimmy, Cindy Stern, Karolina Lisy, Sarahlouise White
BACKGROUND: Osteosarcoma mostly occurs during the period of rapid bone growth in children and adolescents as high-grade osteosarcomas. Current treatment recommended for high-grade non-metastatic and metastatic and/or relapsed osteosarcoma involves neoadjuvant multiagent conventional chemotherapy, followed by surgical resection of macroscopically detected tumor and postoperative adjuvant chemotherapy. However, residual micrometastatic deposits that develop following surgery have shown resistance to postoperative/adjuvant chemotherapy...
August 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28799289/prenatal-exposure-to-fever-is-associated-with-autism-spectrum-disorder-in-the-boston-birth-cohort
#19
Martha Brucato, Christine Ladd-Acosta, Mengying Li, Deanna Caruso, Xiumei Hong, Jamie Kaczaniuk, Elizabeth A Stuart, M Daniele Fallin, Xiaobin Wang
Autism spectrum disorder (ASD) is phenotypically and etiologically heterogeneous, with evidence for genetic and environmental contributions to disease risk. Research has focused on the prenatal period as a time where environmental exposures are likely to influence risk for ASD. Epidemiological studies have shown significant associations between prenatal exposure to maternal immune activation (MIA), caused by infections and fever, and ASD. However, due to differences in study design and exposure measurements no consistent patterns have emerged revealing specific times or type of MIA exposure that are most important to ASD risk...
August 11, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28799220/c-reactive-protein-concentrations-can-help-to-determine-which-febrile-infants-under-three-months-should-receive-blood-cultures-during-influenza-seasons
#20
Weiran Li, Shuanghong Luo, Yu Zhu, Yang Wen, Min Shu, Chaomin Wan
AIM: We explored whether C-reactive protein (CRP) concentrations could indicate which infants with fever without source (FWS) should receive undergo blood culture tests during influenza seasons. METHODS: This retrospective study focused on patients under three months of age with FWS who had received blood culture tests at the West China Second University Hospital Paediatric Emergency Department during the influenza seasons from June 2013 to January 2015. The statistical analysis comprised: specificity, sensitivity, multilevel likelihood ratios, receiver operating characteristic analysis and a multivariate logistic regression model...
August 11, 2017: Acta Paediatrica
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