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Fever in children and infant

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https://www.readbyqxmd.com/read/29868136/prevalence-of-family-history-of-autoimmune-disorders-in-juvenile-systemic-lupus-erythematosus
#1
Parisa Ashournia, Payman Sadeghi, Nima Rezaei, Mohammad-Hassan Moradinejad, Vahid Ziaee
One of the causes of infants' hospitalizations is bronchiolitis, while different viral agents could be causative agents. As there is little information regarding the common agents of bronchiolitis in Iranian infants, we designed this study to determine which agents were responsible for hospitalization due to bronchiolitis among infants in an Iranian tertiary center. Two hundred and three infants with bronchiolitis who were hospitalized in Bahrami hospital were enrolled. Data regarding age, sex, duration of hospitalization, exposure to smoking, previous antibiotic usage and fever were collected for all enrolled cases...
March 2018: Mædica
https://www.readbyqxmd.com/read/29868135/viral-aetiology-of-bronchiolitis-in-hospitalised-children-in-a-tertiary-center-in-tehran
#2
Ali Akbar Rahbarimanesh, Anahita Izadi, Mahsa Ghajarzadeh
One of the causes of infants' hospitalizations is bronchiolitis, while different viral agents could be causative agents. As there is little information regarding the common agents of bronchiolitis in Iranian infants, we designed this study to determine which agents were responsible for hospitalization due to bronchiolitis among infants in an Iranian tertiary center. Two hundred and three infants with bronchiolitis who were hospitalized in Bahrami hospital were enrolled. Data regarding age, sex, duration of hospitalization, exposure to smoking, previous antibiotic usage and fever were collected for all enrolled cases...
March 2018: Mædica
https://www.readbyqxmd.com/read/29858978/is-the-urban-child-health-advantage-declining-in-malawi-evidence-from-demographic-and-health-surveys-and-multiple-indicator-cluster-surveys
#3
Edgar Arnold Lungu, Regien Biesma, Maureen Chirwa, Catherine Darker
In many developing countries including Malawi, health indicators are on average better in urban than in rural areas. This phenomenon has largely prompted Governments to prioritize rural areas in programs to improve access to health services. However, considerable evidence has emerged that some population groups in urban areas may be facing worse health than rural areas and that the urban advantage may be waning in some contexts. We used a descriptive study undertaking a comparative analysis of 13 child health indicators between urban and rural areas using seven data points provided by nationally representative population based surveys-the Malawi Demographic and Health Surveys and Multiple Indicator Cluster Surveys...
June 1, 2018: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/29851943/progress-toward-rubella-and-congenital-rubella-syndrome-control-south-east-asia-region-2000-2016
#4
Sudhir Khanal, Sunil Bahl, Mohammad Sharifuzzaman, Deepak Dhongde, Sirima Pattamadilok, Susan Reef, Michelle Morales, Alya Dabbagh, Katrina Kretsinger, Minal Patel
In 2013, the 66th session of the Regional Committee of the World Health Organization (WHO) South-East Asia Region (SEAR)* adopted the goal of elimination of measles and control† of rubella and congenital rubella syndrome (CRS) by 2020 (1). Rubella is the leading vaccine-preventable cause of birth defects. Although rubella typically causes a mild fever and rash in children and adults, rubella virus infection during pregnancy, especially during the first trimester, can result in miscarriage, fetal death, or a constellation of congenital malformations known as CRS, commonly including visual, auditory, and/or cardiac defects, and developmental delay (2)...
June 1, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29849279/urinary-catheterization-in-infants-when-it-s-knot-so-simple
#5
David C Sheridan, Beech Burns, Megan Mickley
Pediatric fever is one of the most common presenting complaints to emergency departments (ED). While often due to a viral illness, in young children without a source the most common bacterial infection is pyelonephritis. For this reason, when no focal source can be identified a urinary specimen is recommended. In young children who are unable to urinate on demand, a straight catheter is required to obtain a sterile specimen. This is generally a benign procedure and is performed frequently in EDs. We report a case of a young girl who underwent straight bladder catheterization and was subsequently found to have a retained catheter that had become knotted in the bladder...
February 2018: Clinical practice and cases in emergency medicine
https://www.readbyqxmd.com/read/29813148/symptomatic-zika-virus-infection-in-infants-children-and-adolescents-living-in-puerto-rico
#6
Jennifer S Read, Brenda Torres-Velasquez, Olga Lorenzi, Aidsa Rivera Sanchez, Sanet Torres-Torres, Lillian V Rivera, Sheila M Capre-Franceschi, Carlos Garcia-Gubern, Jorge Munoz-Jordan, Gilberto A Santiago, Luisa I Alvarado
Importance: Little information is available regarding Zika virus (ZIKV) infection in children. Objective: To describe patients younger than 18 years who were infected with ZIKV and were enrolled in the Sentinel Enhanced Dengue and Acute Febrile Illness Surveillance System (SEDSS). Design, Setting, and Participants: Children infected with ZIKV with 7 or fewer days of fever or emancipated minors aged 14 to 17 years with a generalized maculopapular rash, arthritis or arthralgia, or nonpurulent conjunctivitis were eligible for enrollment on or before December 31, 2016, in Puerto Rico...
May 29, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29790830/empyema-necessitans-in-a-six-month-old-girl
#7
P Goussard, Robert Gie, Jacques Janson, Savvas Andronikou
Empyema necessitans is a rare complication of acute bacterial pneumonia, especially in children. It is a complication of empyema characterised by the extension of pus from the pleural cavity into the thoracic wall to form a mass of purulent fluid in the adjacent soft tissue. An inflammatory chest wall mass following pneumonia caused by Streptococcus pneumonia in a six-month-old infant is reported. The case emphasises that children presenting with persistent fever and a painful chest wall mass following pneumonia should be investigated immediately as there might be an urgent need for surgery...
May 23, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29780032/severe-outcomes-associated-with-respiratory-viruses-in-newborns-and-infants-a-prospective-viral-surveillance-study-in-jordan
#8
Najwa Khuri-Bulos, Lindsey Lawrence, Bhinnata Piya, Li Wang, Christopher Fonnesbeck, Samir Faouri, Asem Shehabi, Sten H Vermund, John V Williams, Natasha B Halasa
OBJECTIVE: To assess virus-specific hospitalisation rates, risk factors for illness severity and seasonal trends in children hospitalised with acute respiratory infections (ARI). DESIGN: Prospective cohort study. SETTING: A government hospital serving low-income and middle-income population in Amman, Jordan. PARTICIPANTS: Children under 2 years of age hospitalised with fever and/or respiratory symptoms (n=3168) from 16 March 2010 to 31 March 2013...
May 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29776433/bordetella-pertussis-in-children-hospitalized-with-a-respiratory-infection-clinical-characteristics-and-pathogen-detection-in-household-contacts
#9
Juana Del Valle-Mendoza, Wilmer Silva-Caso, Miguel Angel Aguilar-Luis, Cristina Del Valle-Vargas, Erico Cieza-Mora, Johanna Martins-Luna, Ronald Aquino-Ortega, Andrea Silva-Vásquez, Jorge Bazán-Mayra, Pablo Weilg
OBJECTIVE: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. RESULTS: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%)...
May 18, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29760843/multicenter-study-of-albuterol-use-among-infants-hospitalized-with-bronchiolitis
#10
Anna Condella, Jonathan M Mansbach, Kohei Hasegawa, Peter S Dayan, Ashley F Sullivan, Janice A Espinola, Carlos A Camargo
Introduction: Although bronchiolitis is a common reason for infant hospitalization, significant heterogeneity persists in its management. The American Academy of Pediatrics currently recommends that inhaled albuterol not be used in routine care of children with bronchiolitis. Our objective was to identify factors associated with pre-admission (e.g., emergency department or primary care) use of albuterol among infants hospitalized for bronchiolitis. Methods: We analyzed data from a 17-center observational study of 1,016 infants (age <1 year) hospitalized with bronchiolitis between 2011-2014...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29750741/hemophagocytic-lymphohystiocytosis-associated-with-type-ia-glycogen-storage-disease
#11
Yeter Düzenli Kar, Zeynep C Özdemir, Eylem Kiral, Gonca Kiliç Yildirim, Ener Ç Dinleyici, Özcan Bör
BACKGROUND: Hemophagocytic lymphohystiocytosis (HLH) is characterized by fever, splenomegaly, pancytopenia, and elevated levels of triglycerides and ferritin. These signs and symptoms are common to other metabolic diseases. OBSERVATION: A 5-month-old female infant, who presented with fever, respiratory distress, massive hepatomegaly, and bicytopenia, was diagnosed as having HLH and chemotherapy was initiated. The patient was negative for familial HLH gene mutations...
May 10, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29748704/subdural-empyema-due-to-salmonella-paratyphi-b-in-an-infant-a-case-report-and-review-of-literature
#12
Vijai Williams, Keshavamurthy Mysore Lakshmikantha, Karthi Nallasamy, K C Sudeep, Arun Kumar Baranwal, Muralidharan Jayashree
Intracranial infection due to Salmonella is uncommon in children. Subdural empyema (SDE) is described with Salmonella typhi as a complication of meningitis. We report a 6-month-old infant with SDE secondary to Salmonella paratyphi B who had presented with prolonged fever and enlarging head. A literature review of Salmonella SDE in infants with respect to clinical course and outcome is presented.
May 10, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29736610/occult-bacteremia-etiology-following-the-introduction-of-13-valent-pneumococcal-conjugate-vaccine-a-multicenter-study-in-spain
#13
Susanna Hernández-Bou
Little is known about occult bacteremia (OB) in Spain following the introduction of the 13-valent pneumococcal conjugated vaccine (PCV13). Our aim was to describe the microbiologic characteristics and management of OB among children aged 3-36 months in Spain in the era of PCV13. Data were obtained from a multicenter registry of positive blood cultures collected at 22 Spanish emergency departments (ED). Positive blood cultures performed on patients aged 3-36 months from 2011 to 2015 were retrospectively identified...
May 7, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29731834/diagnosis-and-treatment-of-postoperative-intestinal-perforation-in-infants-and-young-children-with-congenital-heart-disease-a-report-of-three-cases
#14
Yong-Hong Zhang, Zhen-Liang Chen, Lei Shi, Zhong-Jian Chen, Xiang-Yang Dong, Bo Zhai
The aim of the present study was to analyze risk factors of intestinal perforation following surgery for the treatment of congenital heart disease in infants and young children, and to summarize experiences of diagnosis and treatment. A total of 3,270 children, who underwent congenital heart disease surgery under extracorporeal circulation from January 2010 to July 2015, were retrospectively analyzed. Among these children, three (0.09%) developed postoperative intestinal perforation. Primary diseases were Tetralogy of Fallot (two cases) and ventricular septal defect combined with atrial septal defect (one case)...
May 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29731283/atypical-presentation-of-incomplete-kawasaki-disease-a-peripheral-facial-nerve-palsy
#15
Moises Rodriguez-Gonzalez, Ana Castellano-Martinez, Alvaro A Perez-Reviriego
BACKGROUND: Kawasaki disease (KD) is a multisystem vasculitic disease. Coronary artery aneurysms (CAAs) are the most important and life-threatening complication of KD. Various neurologic complications have been described to occur in 1-30% of patients with KD, but peripheral facial nerve palsy (FNP) is rare (0.9%). CASE REPORT: We describe a 5-month-old male infant who presented to us with unilateral left infranuclear FNP in the convalescent phase (day 18 of illness) of incomplete KD...
May 3, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29716506/parechovirus-an-important-emerging-infection-in-young-infants
#16
Philip N Britton, Cheryl A Jones, Kristine Macartney, Allen C Cheng
Epidemics of human parechovirus (HPeV) causing disease in young children have occurred every 2 years in Australia since 2013. HPeV genotype 3 caused the epidemic from late 2017 to early 2018. Most HPeV infections cause no or mild symptoms including gastroenteritis or influenza-like illness. Characteristically, young infants present with fever, irritability and on occasions a diffuse rash ("red, hot and angry" babies). Severe disease can manifest as meningoencephalitis, seizures or sepsis-like presentations (including septic shock), or less common presentations including signs of surgical abdomen...
May 7, 2018: Medical Journal of Australia
https://www.readbyqxmd.com/read/29709990/human-parechovirus-infection-in-children-in-taiwan-a-retrospective-single-hospital-study
#17
Jenn-Tzong Chang, Yao-Shen Chen, Bao-Chen Chen, Tsi-Shu Huang, Tsung-Hsien Chang
To understand human parechovirus (HPeV) infections in Taiwanese children, we analyzed data for 112 children (age ≤ 10 years) with HPeV infection diagnosed from July 2007 to June 2016 in a medical centre in Kaohsiung, southern Taiwan. Infection was with HPeV1 (n=94), HPeV3 (n=3), HPeV4 (n=3), HPeV6 (n=1) and non-typeable HPeV (n=11). We compared the clinical implication for children younger than 3 months (n=56) and 3 months and older (n=31), excluding the 25 children with concomitant infection. Fever was noted in almost half of the children younger than 3 months but was more frequent in older than younger children (83...
April 27, 2018: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29698412/clinical-manifestations-in-infants-and-children-with-mycoplasma-pneumoniae-infection
#18
Mia Johanna Søndergaard, Martin Barfred Friis, Dennis Schrøder Hansen, Inger Merete Jørgensen
BACKGROUND: Mycoplasma pneumoniae is a common cause of community-acquired pneumonia in older children. Pulmonary and extra-pulmonary symptoms associated with M. pneumoniae infection are reported. M. pneumoniae is mainly epidemic in Denmark with the recurrence every 4-7th year. AIMS: Retrospectively, to describe the epidemiology and clinical features, in infants and children, during the M. pneumoniae epidemic in 2010 and 2011. METHODS: All children under the age of 16 that were tested for M...
2018: PloS One
https://www.readbyqxmd.com/read/29686701/nontyphoidal-salmonella-gastroenteritis-in-a-tertiary-children-s-hospital-in-southern-china-characteristics-and-dietary-considerations
#19
Lu Ren, Min Yang, Lanlan Geng, Peiyu Chen, Huan Chen, Sitang Gong, Ding-You Li
Background: Nontyphoidal Salmonella infection is a common cause for acute bacterial gastroenteritis in children in China. There have been no reports of the prevalence of lactose intolerance or food allergies in children with nontyphoidal Salmonella infection. The aim of this study was to characterize nontyphoidal Salmonella gastroenteritis in a tertiary children's hospital and evaluate clinical presentation, lactose intolerance, and food allergies in children with prolonged nontyphoidal Salmonella gastroenteritis...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29669531/assessment-of-an-optimized-manufacturing-process-for-inactivated-quadrivalent-influenza-vaccine-a-phase-iii-randomized-double-blind-safety-and-immunogenicity-study-in-children-and-adults
#20
Carine Claeys, Mamadou Drame, José García-Sicilia, Khalequ Zaman, Alfonso Carmona, Phu My Tran, Mariano Miranda, Federico Martinón-Torres, Franck Thollot, Michael Horn, Tino F Schwarz, Ulrich Behre, José M Merino, Iwona Sadowska-Krawczenko, Henryk Szymański, Peter Schu, Elisabeth Neumeier, Ping Li, Varsha K Jain, Bruce L Innis
BACKGROUND: GSK has modified the licensed monovalent bulk manufacturing process for its split-virion inactivated quadrivalent influenza vaccine (IIV4) to harmonize the process among different strains, resulting in an increased number of finished vaccine doses, while compensating for the change from inactivated trivalent influenza vaccine (IIV3) to IIV4. To confirm the manufacturing changes do not alter the profile of the vaccine, a clinical trial was conducted to compare IIV4 made by the currently licensed process with a vaccine made by the new (investigational) process (IIV4-I)...
April 18, 2018: BMC Infectious Diseases
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