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https://www.readbyqxmd.com/read/29035302/oligoarticular-hemarthroses-and-osteomyelitis-complicating-pasteurella-meningitis-in-an-infant
#1
Charles Nathan Nessle, Allison K Black, Justin Farge, Victoria A Statler
A 5-month-old previously healthy female presented with a one-week history of fever and increased fussiness. Her presentation revealed an ill-appearing infant with an exam and cerebrospinal fluid (CSF) studies concerning bacterial meningitis; CSF cultures grew Pasteurella multocida. Additionally, brain magnetic resonance imaging (MRI) demonstrated cervical osteomyelitis. Despite multiple days of antibiotic therapy, she remained febrile with continued pain; MRI showed oligoarticular effusions, and aspiration of these joints yielded bloody aspirates...
October 16, 2017: Children
https://www.readbyqxmd.com/read/29034761/knowledge-and-attitude-of-mothers-regarding-infant-hearing-loss-in-changsha-hunan-province-china
#2
Xiaoli Wang, Dan Wu, Yali Zhao, Danhui Li, Dinghua He
OBJECTIVE: The objective of this study was to explore the knowledge and attitude among mothers of newborns regarding infant hearing loss (HL) in Changsha, Hunan province, China. DESIGN: A questionnaire including 18 items was given to mothers. STUDY SAMPLE: A total of 115 mothers participated in the study. RESULTS: Seven risk factors for hearing loss were identified correctly by above 60% of respondents and the top three were prolonged noise (88...
October 16, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/29020247/assessment-of-efficacy-and-safety-of-arterolane-maleate-piperaquine-phosphate-dispersible-tablets-in-comparison-with-artemether-lumefantrine-dispersible-tablets-in-pediatric-patients-with-acute-uncomplicated-plasmodium-falciparum-malaria-a-phase-3-randomized
#3
Offianan Andre Toure, Victor Mwapasa, Issaka Sagara, Oumar Gaye, Ricardo Thompson, Aishwarya V Maheshwar, Pitabas Mishra, Narendra Behra, Antoinette K Tshefu, Rashmi R Das, Anupkumar R Anvikar, Pradeep Sharma, Arjun Roy, Sanjay K Sharma, Amit Nasa, Rajinder K Jalali, Neena Valecha
Background: Administration of artemisinin-based combination therapy (ACT) to infant and young children can be challenging. A formulation with accurate dose and ease of administration will improve adherence and compliance in children. The fixed-dose combination dispersible tablet of arterolane maleate (AM) 37.5 mg and piperaquine phosphate (PQP) 187.5 mg can make dosing convenient in children. Methods: This multicenter (India and Africa), comparative, parallel-group trial enrolled 859 patients aged 6 months to 12 years with Plasmodium falciparum malaria...
August 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29016324/hemoglobin-levels-and-the-risk-of-malaria-in-papua-new-guinean-infants-a-nested-cohort-study
#4
Patrick Lombardo, Paul Vaucher, Patricia Rarau, Ivo Mueller, Bernard Favrat, Nicolas Senn
Studies are available that assess the risk of malaria in accordance to the body's iron store and the systematic iron supplementation of preschool children. However, only a few studies evaluated the temporal association between hemoglobin and malaria and their results are opposing. A total of 1,650 3-month-old Papua New Guinean infants were enrolled in this study and followed-up for 12 months. The risk of malaria was assessed in all children every 3 months and with each episode of fever. The incidence of clinical malaria between 3 and 15 months of age was 249 cases per 1,000 infants per year...
September 25, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28993356/life-threatening-parapharyngeal-and-retropharyngeal-abscess-in-an-infant
#5
Anusha Balasubramanian, J Redzwan Shah, Norzi Gazali, Philip Rajan
Severe extensive deep neck abscess in an infant is uncommon. We share the case of a previously well 4-month old infant who was referred for a 4-day history of fever, lethargy and left lateral neck swelling. Contrast-enhanced CT scan revealed a large 5.3×8 cm collection involving the left parapharyngeal and retropharyngeal space, causing significant airway narrowing. 40 mL of frank pus was drained via intraoral incision and drainage with the aid of endoscope, and undesirable complications from an external approach were averted...
October 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28989154/-influential-factors-associated-with-2-week-prevalence-of-fever-and-diarrhea-among-infants-and-young-children-at-the-age-of-6-23-months-in-poor-rural-areas
#6
Xu Zhou, Junqun Fang, Jiayou Luo, Hua Wang, Qiyun Du, Guangwen Huang, Binbin Feng, Qinghua Quan
To investigate the status and influential factors associated with 2-week prevalence of fever and diarrhea among infants and young children at the age of 6-23 months in poor rural areas.
 Methods: A total of 8 735 rural infants and young children aged 6-23 months in 30 poor counties of Wuling Mountains and Luoxiao Mountains in Hunan Province were selected in August 2015, and the questionnaires were used to collect information on the prevalence of fever and diarrhea, person and families, and feeding status...
September 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28965695/-evaluating-a-child-after-a-febrile-seizure-insights-on-three-important-issues
#7
S Auvin, M Antonios, G Benoist, M-A Dommergues, F Corrard, V Gajdos, C Gras Leguen, E Launay, A Salaün, L Titomanlio, L Vallée, M Milh
Febrile seizures (FS) are the most common seizures seen in the paediatric population in the out-of-hospital and emergency department settings, and they account for the majority of seizures seen in children younger than 5 years old. An FS is a seizure accompanied by fever, without central nervous system infection, occurring in children between 6 months and 5 years old. Five criteria have been used and taught to classify any FS as simple or complex FS. These factors do not bear the same significance for clinical practice, in particular, the decision to perform a lumbar puncture for cerebrospinal fluid analysis to rule out an intracranial infection...
September 28, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28962118/clinical-characteristics-and-electroencephalogram-analysis-of-levetiracetam-in-the-treatment-of-children-with-febrile-seizure-recurrence
#8
Xue-Chao Li, Ling-Ling Lu, Jian-Zhong Wang, Miao Wang, Yu Gao, Ye-Xin Lin, Zhong-Hou Han
Febrile seizure is the most common neurologic disorder in infants and children. This study aimed to elaborate safe and effective therapy for preventing FS recurrence by levetiracetam (LEV). A prospective study was performed in two groups of children, the no treatment group (n=51, 24.1±9.0 months) and the LEV treatment group (n=45, 23.3±8.9 months). The findings demonstrated that a significant difference (P<0.01) was observed between the no treatment group 51.0% (26/51) and LEV treatment group 15.5% (7/45) in terms of FS recurrence after 50 weeks...
September 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28958813/chronovac-voyageur-a-study-of-the-immune-response-to-yellow-fever-vaccine-among-infants-previously-immunized-against-measles
#9
Catherine Goujon, Marie-Lise Gougeon, Laura Tondeur, Béatrice Poirier, Valérie Seffer, Philippe Desprès, Paul-Henri Consigny, Muriel Vray
For administration of multiple live attenuated vaccines, the Advisory Committee on Immunization Practices recommends either simultaneous immunization or period of at least 28days between vaccines, due to a possible reduction in the immune response to either vaccine. The main objective of this study was to compare the immune response to measles (alone or combined with mumps and rubella) and yellow fever vaccines among infants aged 6-24months living in a yellow fever non-endemic country who had receivedmeasles and yellow fever vaccines before travelling to a yellow fever endemic area...
October 27, 2017: Vaccine
https://www.readbyqxmd.com/read/28958731/brainstem-infarction-associated-with-hhv-6-infection-in-an-infant
#10
Aya Wada, Kazuhiro Muramatsu, Yasuo Sunaga, Takahisa Mizuno, Mariko Takei, Satoshi Ogasawara, Miho Uchida, Kiwako Tsukida, Masahiko Tashiro
INTRODUCTION: The relevant literature includes several case reports on cerebral infarction in children with HHV-6 infection; however, there is no report of brain stem infarction. CASE: An 11-month-old girl was hospitalized because of fever. She was unable to stand up and meet her mother's gaze. Magnetic resonance imaging (MRI) indicated a right pons and mid-brain lesion; a diagnosis of brainstem infarction was made. After her fever subsided, a rash developed on her trunk and limbs; blood examination results indicated a primary HHV-6 infection...
September 25, 2017: Brain & Development
https://www.readbyqxmd.com/read/28946922/nbas-mutations-cause-acute-liver-failure-when-acetaminophen-is-not-a-culprit
#11
Pier Luigi Calvo, Francesco Tandoi, Tobias B Haak, Andrea Brunati, Michele Pinon, Dominic Dell Olio, Renato Romagnoli, Marco Spada
BACKGROUND: Pediatric acute-liver-failure due to acetaminophen (APAP) administration at therapeutic dosage is rare, while viral infections and metabolic defects are the prevalent causes. Yet, as acetaminophen is routinely used in febrile illnesses, it may be mistakenly held responsible for the acute liver damage. CASE PRESENTATION: An 11 month old boy had been on acetaminophen for 10 days (total dose 720 mg = 72 mg/kg) when he developed acute-liver-failure with encephalopathy...
September 25, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28942395/fever-marked-tachycardia-and-vesiculobullous-rash-in-an-infant-with-chikungunya-fever
#12
Nirupa Chandorkar, Dinesh Raj, Ramesh Kumar, Sumbul Warsi
We describe a 3-month-old male infant who presented with acute onset fever, irritability and marked tachycardia. ECG was suggestive of atrial tachycardia. He developed erythematous blanchable skin rash on day 2 of illness, which progressed to vesiculobullous lesions over a few days' time. The child was managed with intravenous adenosine, carefully monitored fluid boluses, oxygen supplementation and close monitoring. Tachycardia improved within 24 hours. Blood for Chikungunya PCR was positive. The child was discharged after 5 days of hospitalisation with bullous lesions evolving into hyperpigmented macules followed by crusts and hypopigmentation by day 10...
September 23, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28940983/changes-in-trends-and-impact-of-testing-for-influenza-in-infants-with-fever-under-90-days-of-age
#13
Suji Kim, Hye Min Moon, Joon Kee Lee, Kyuyol Rhie, Ki Wook Yoon, Eun Hwa Choi, Hoan Jong Lee, Hyunju Lee
BACKGROUND: Infants less than 90 days who present with fever are commonly subject to various invasive procedures due to risk of bacterial infections in this age group. However a great proportion are due to viral infections, including influenza. The aim of this study was to assess the impact of testing influenza in infants < 90 days with fever as well as analyze the subjects' characteristics to identify which infants should be considered for such testing. METHODS: Clinical characteristics and trends in influenza virus testing and treatment were analyzed among febrile infants <90 days who came to the emergency room and were diagnosed with influenza during 2005 to 2015...
September 22, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28940750/performing-a-urine-dipstick-test-with-a-clean-catch-urine-sample-is-an-accurate-screening-method-for-urinary-tract-infections-in-young-infants
#14
María Luisa Herreros, Alfredo Tagarro, Araceli García-Pose, Aida Sánchez, Alfonso Cañete, Pablo Gili
AIM: This study evaluated using urine dipstick tests with the clean-catch method to screen for urinary tract infection (UTI) in febrile infants under 90 days of age. METHODS: We carried out a comparative diagnostic accuracy study of infants under 90 days old, who were studied for unexplained fever without any source, in the emergency room of a hospital in Madrid from January 2011 to January 2013. We obtained matched samples of urine using two different methods: a clean-catch, standardised stimulation technique and catheterisation collection...
September 23, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28937791/web-based-surveillance-of-illness-in-childcare-centers
#15
Natalie Schellpfeffer, Abaigeal Collins, David C Brousseau, Emily T Martin, Andrew Hashikawa
School absenteeism is an inefficient and unspecific metric for measuring community illness and does not provide surveillance during summertime. Web-based biosurveillance of childcare centers may represent a novel way to efficiently monitor illness outbreaks year-round. A web-based biosurveillance program ( sickchildcare.org ) was created and implemented in 4 childcare centers in a single Michigan county. Childcare providers were trained to report sick children who required exclusion or had parent-reported absences due to illness...
September 22, 2017: Health Security
https://www.readbyqxmd.com/read/28928611/brugada-syndrome-in-children-stepping-into-unchartered-territory
#16
REVIEW
Shashank P Behere, Steven N Weindling
Brugada syndrome (BrS) is an autosomal dominant inherited channelopathy. It is associated with a typical pattern of ST-segment elevation in the precordial leads V1-V3 and potentially lethal ventricular arrhythmias in otherwise healthy patients. It is frequently seen in young Asian males, in whom it has previously been described as sudden unexplained nocturnal death syndrome. Although it typically presents in young adults, it is also known to present in children and infants, especially in the presence of fever...
September 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28912993/bilateral-peritonsillar-abscess-in-an-infant-an-unusual-presentation-of-sore-throat
#17
Mariana Manzoni Seerig, Letícia Chueiri, Janaina Jacques, Maria Fernanda Piccoli Cardoso de Mello, Martin Batista Coutinho da Silva, Daniel Buffon Zatt, Rosana Cristine Otero Cunha, Andre Souza de Albuquerque Maranhão
INTRODUCTION: Peritonsillar abscess is considered a suppurative complication of acute tonsillitis. It is usually unilateral and clinically evident bilateral presentation is uncommon. The condition affects mainly children older than 10 years and young adults. Herein we present a rare case of bilateral peritonsillar abscess in an infant. PRESENTATION OF CASE: A 1-year-old boy presented with a two-day history of worsening sore throat, loss of appetite, vomiting, and fever...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28903515/update-from-the-advisory-committee-on-immunization-practices
#18
Sean T O'Leary, Yvonne A Maldonado, Carrie L Byington
The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. The group has 15 voting members, and each member's term is 4 years. ACIP members and Centers for Disease Control and Prevention (CDC) staff discuss the epidemiology of vaccine-preventable diseases and vaccine research, effectiveness, safety data, and clinical trial results. Representatives from the American Academy of Pediatrics (C...
September 1, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28902298/nursing-infant-with-acquired-toxoplasmosis-in-the-first-months-of-life-a-case-report
#19
Hanstter Hallison Alves Rezende, Heloísa Ribeiro Storchilo, Jaqueline Ataíde Silva Lima, Antônio Roberto Gomes, Taynara Cristina Gomes, Jéssica Yonara de Souza, Mariza Martins Avelino, Waldemar Naves do Amaral, Marina Clare Vinaud, Ana Maria de Castro
Toxoplasmosis is caused by Toxoplasma gondii and the probability of this infection occurring in the first months of life is usually low because its transmission is related to eating habits. A 6-month-old nursing infant was diagnosed with acute toxoplasmosis, which was identified through anti- T. gondii IgA, IgM and low-avidity IgG serologic assays, polymerase chain reaction (PCR) and mouse bioassay test although its mother was seronegative. This serological divergence between mother and child led us to interview the mother regarding epidemiological factors...
August 24, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28894118/persistence-of-zika-virus-in-conjunctival-fluid-of-convalescence-patients
#20
Jeslin J L Tan, Praveen K Balne, Yee-Sin Leo, Louis Tong, Lisa F P Ng, Rupesh Agrawal
A widespread epidemic of Zika fever, caused by Zika virus (ZIKAV) has spread throughout the Pacific islands, the Americas and Southeast Asia. The increased incidences of ocular anomalies observed in ZIKAV-infected infants and adults may be associated with the rapid spread of ZIKAV. The objective of this study was to check if ZIKAV could be detected in human tears after the first week of infection. Twenty-nine patients with PCR confirmed ZIKAV infection during the Singapore August 2016 ZIKAV outbreak were enrolled for the study...
September 11, 2017: Scientific Reports
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