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Clostridium butyricum

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https://www.readbyqxmd.com/read/28994162/effect-of-probiotics-on-perinatal-outcome-in-patients-at-high-risk-of-preterm-birth
#1
Nami Kirihara, Masato Kamitomo, Tatsunori Tabira, Takashi Hashimoto, Hiroko Taniguchi, Takatsugu Maeda
AIM: Recent reports have shown lower levels of Clostridium and higher levels of Lactobacillales in the intestinal microbiota in preterm birth patients compared to term birth patients. However, the influence of probiotics on perinatal status has not been elucidated. The aim of our study was to evaluate the effects of probiotics on perinatal outcomes. METHODS: We retrospectively evaluated the effects of oral probiotics on perinatal outcome in patients at high risk of preterm birth...
October 10, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28935752/erratum-for-halpin-et-al-finished-whole-genome-sequences-of-clostridium-butyricum-toxin-subtype-e4-and-clostridium-baratii-toxin-subtype-f7-strains
#2
Jessica L Halpin, Karen Hill, Shannon L Johnson, David Carlton Bruce, T Brian Shirey, Janet K Dykes, Carolina Lúquez
No abstract text is available yet for this article.
September 21, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28933492/the-hepatoprotective-effect-of-the-probiotic-clostridium-butyricum-against-carbon-tetrachloride-induced-acute-liver-damage-in-mice
#3
Jiaming Liu, Yaoyang Fu, Hao Zhang, Jindan Wang, Jing Zhu, Yaqi Wang, Yuegui Guo, Guocan Wang, Tianqi Xu, Maoping Chu, Fangyan Wang
Previous studies have revealed that the probiotic Clostridium butyricum (C. butyricum) can attenuate cirrhosis in chronic non-alcoholic liver disease. However, the effects of C. butyricum on acute liver injury (ALI) remain unclear. Therefore, the present study aims to examine the hepatoprotective effects and the underlying mechanisms employed by C. butyricum in a carbon tetrachloride (CCl4)-induced ALI murine model. Here, we evaluated the survival rate and the levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), anti-oxidants, cytokines and the gut microbiota to elucidate the potential mechanisms by which C...
September 21, 2017: Food & Function
https://www.readbyqxmd.com/read/28859498/influence-of-human-milk-oligosaccharides-on-adherence-of-bifidobacteria-and-clostridia-to-cell-lines
#4
Sarka Musilova, Nikol Modrackova, Ivo Doskocil, Roman Svejstil, Vojtech Rada
Adhesion of gut bacteria to the intestinal epithelium is the first step in their colonization of the neonatal immature gut. Bacterial colonization of the infant gut is influenced by several factors, of which the most important are the mode of delivery and breast-feeding. Breast-fed infants ingest several grams of human milk oligosaccharides (HMOs) per day, which can become receptor decoys for intestinal bacteria. The most abundant intestinal bacteria in vaginally delivered infants are bifidobacteria, whereas infants born by cesarean section are colonized by clostridia...
September 1, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28843121/exploring-the-microbial-origins-of-p-cresol-and-its-co-occurrence-pattern-in-the-chinese-liquor-making-process
#5
Hai Du, Bo Liu, Xueshan Wang, Yan Xu
The compound p-cresol is the major off-odor and toxic component of strong aroma-type Chinese liquor. To trace its origin, the p-cresol contents in the liquor-making process were detected by gas chromatography-mass spectrometry. The prokaryotic communities involved in the process were revealed by 16S rRNA gene MiSeq sequencing. The results showed that the microbial diversity and concentration of p-cresol in pit mud significantly increased with increased pit depth. Canonical correspondence analysis further revealed that p-cresol was positively correlated with the genera Aminobacterium, Clostridium, Sedimentibacter and Syntrophomonas...
August 19, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28832229/effects-of-polysaccharide-from-physalis-alkekengi-var-francheti-on-liver-injury-and-intestinal-microflora-in-type-2-diabetic-mice
#6
Xin Zhao, Ziyang Chen, Yuling Yin, Xinli Li
CONTEXT: Diabetic liver injury is a serious diabetic complication. The alterations of intestinal microbiota play an important role in induction and promotion of liver injury progression. Physalis alkekengi L. var. francheti (Mast.) Makino (Solanaceae) has been used as a water decoction for treating diabetes. OBJECTIVE: To study the effects of a polysaccharide (PPSB) from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28765642/anti-diabetic-effects-of-clostridium-butyricum-cgmcc0313-1-through-promoting-the-growth-of-gut-butyrate-producing-bacteria-in-type-2-diabetic-mice
#7
Lingling Jia, Dongyao Li, Ninghan Feng, Muhammad Shamoon, Zhenghua Sun, Lei Ding, Hao Zhang, Wei Chen, Jia Sun, Yong Q Chen
Patients with type 2 diabetes (T2D) have decreased butyrate-producing bacteria. We hypothesized that supplementation with butyrate-producing bacteria may exert beneficial effects on T2D. The current study investigated the effects of well-characterized butyrate-producing bacteria Clostridium butyricum CGMCC0313.1 (CB0313.1) on hyperglycemia and associated metabolic dysfunction in two diabetic mouse models. CB0313.1 was administered daily by oral gavage to leptin (db/db) mice for 5 weeks starting from 3 weeks of age, and to HF diabetic mice induced by high fat diet (HFD) plus streptozotocin (STZ) in C57BL/6J mice for 13 weeks starting from 4 weeks of age...
August 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28761060/administration-of-lactobacillus-salivarius-li01-or-pediococcus-pentosaceus-li05-prevents-ccl4-induced-liver-cirrhosis-by-protecting-the-intestinal-barrier-in-rats
#8
Ding Shi, Longxian Lv, Daiqiong Fang, Wenrui Wu, Chenxia Hu, Lichen Xu, Yanfei Chen, Jing Guo, Xinjun Hu, Ang Li, Feifei Guo, Jianzhong Ye, Yating Li, Dewi Andayani, Lanjuan Li
Alterations in the gut microbiome have been reported in liver cirrhosis, and probiotic interventions are considered a potential treatment strategy. This study aimed to evaluate the effects and mechanisms of Lactobacillus salivarius LI01, Pediococcus pentosaceus LI05, Lactobacillus rhamnosus GG, Clostridium butyricum MIYAIRI and Bacillus licheniformis Zhengchangsheng on CCl4-induced cirrhotic rats. Only administration of LI01 or LI05 prevented liver fibrosis and down-regulated the hepatic expression of profibrogenic genes...
July 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28754474/description-of-absiella-argi-gen-nov-sp-nov-and-transfer-of-eubacterium-dolichum-and-eubacterium-tortuosum-to-the-genus-absiella-as-absiella-dolichum-comb-nov-and-absiella-tortuosum-comb-nov
#9
Jayoung Paek, Yeseul Shin, Joong-Su Kim, Hongik Kim, Joong-Ki Kook, Woon Kee Paek, Young-Hyo Chang
Gram-positive, straight or slightly curved rod-shaped bacteria, designated as strains N6H1-5(T) and N6H1-3, were isolated from fecal samples of old dog. The analysis of 16S rRNA gene sequences indicated that the isolates belonged to the Clostridium cluster XVI and were closely related to Eubacterium dolichum KCTC 5832(T), Eubacterium tortuosum DSM 3987(T), Clostridium innocuum KCTC 5183(T), Allobaculum stecoricanis DSM 13633(T), Eubacterium limosum KCTC 3266(T), and Clostridium butyricum KCTC 1871(T), with 94...
July 25, 2017: Anaerobe
https://www.readbyqxmd.com/read/28739338/comparative-phenotypic-analysis-of-clostridium-neonatale-and-clostridium-butyricum-isolates-from-neonates
#10
S Schönherr-Hellec, G Klein, J Delannoy, L Ferraris, I Friedel, J C Rozé, M J Butel, J Aires
"Clostridium neonatale" was recently described as a new species within the Cluster I of the Clostridium genus sensu stricto. In this study, we characterized "C. neonatale" isolates (n = 42) and compared their phenotypic properties with those of Clostridium butyricum (n = 26), a close related species. Strains isolated from fecal samples of healthy neonates were tested for different phenotypic characteristics. Compared to C. butyricum, "C. neonatale" showed a significant higher surface hydrophobicity (p = 0...
July 21, 2017: Anaerobe
https://www.readbyqxmd.com/read/28729254/finished-whole-genome-sequences-of-clostridium-butyricum-toxin-subtype-e4-and-clostridium-baratii-toxin-subtype-f7-strains
#11
Jessica L Halpin, Karen Hill, Shannon L Johnson, David Carlton Bruce, T Brian Shirey, Janet K Dykes, Carolina Lúquez
Clostridium butyricum and Clostridium baratii species have been known to produce botulinum toxin types E and F, respectively, which can cause botulism, a rare but serious neuroparalytic disease. Here, we present finished genome sequences for two of these clinically relevant strains.
July 20, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28681177/efficacy-and-safety-of-probiotic-supplemented-triple-therapy-for-eradication-of-helicobacter-pylori-in-children-a-systematic-review-and-network-meta-analysis
#12
REVIEW
Jue-Rong Feng, Fan Wang, Xiao Qiu, Lynne V McFarland, Peng-Fei Chen, Rui Zhou, Jing Liu, Qiu Zhao, Jin Li
AIM: The aim of this study was to identify the best probiotic supplementation in triple therapy for pediatric population with Helicobacter pylori infection. METHODS: Eligible trials were identified by comprehensive searches. Relative risks with 95% confidence intervals and relative ranks with P scores were assessed. RESULTS: Twenty-nine trials (3122 participants) involving 17 probiotic regimens were identified. Compared with placebo, probiotic-supplemented triple therapy significantly increased H...
July 5, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28571567/clostridium-butyricum-maximizes-growth-while-minimizing-enzyme-usage-and-atp-production-metabolic-flux-distribution-of-a-strain-cultured-in-glycerol
#13
Luis Miguel Serrano-Bermúdez, Andrés Fernando González Barrios, Costas D Maranas, Dolly Montoya
BACKGROUND: The increase in glycerol obtained as a byproduct of biodiesel has encouraged the production of new industrial products, such as 1,3-propanediol (PDO), using biotechnological transformation via bacteria like Clostridium butyricum. However, despite the increasing role of Clostridium butyricum as a bio-production platform, its metabolism remains poorly modeled. RESULTS: We reconstructed iCbu641, the first genome-scale metabolic (GSM) model of a PDO producer Clostridium strain, which included 641 genes, 365 enzymes, 891 reactions, and 701 metabolites...
June 1, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/28539294/-effects-of-clostridium-butyricum-on-serum-uric-acid-and-inflammatory-mediators-in-rats-with-hyperuricemia
#14
Li Wang, Zhi-Rong Fang, Ya-Ting Shen, Yan-Bo Liu, Li-Li Liu
OBJECTIVE: To investigate the effects of intragastric administration of Clostridium butyricum in regulating serum uric acid, lipopolysaccharides (LPS), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in rats with hyperuricemia rats. METHODS: Forty SD rats were randomized into 4 equal groups, namely the normal control group, hyperuricemia model group, benzbromarone (3 mg/kg daily) intervention group and live Clostridium butyricum group (1.5×10(7) CFU/day)...
May 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28536840/insights-from-the-complete-genome-sequence-of-clostridium-tyrobutyricum-provide-a-platform-for-biotechnological-and-industrial-applications
#15
Qian Wu, Tingting Liu, Liying Zhu, He Huang, Ling Jiang
Genetic research enables the evolution of novel biochemical reactions for the production of valuable chemicals from environmentally-friendly raw materials. However, the choice of appropriate microorganisms to support these reactions, which must have strong robustness and be capable of a significant product output, is a major difficulty. In the present study, the complete genome of the Clostridium tyrobutyricum strain CCTCC W428, a hydrogen- and butyric acid-producing bacterium with increased oxidative tolerance was analyzed...
August 2017: Journal of Industrial Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28528789/mixed-culture-h2-fermentation-performance-and-the-relation-between-microbial-community-composition-and-hydraulic-retention-times-for-a-fixed-bed-reactor-fed-with-galactose-glucose-mixtures
#16
Parthiban Anburajan, Jong-Hun Park, Periyasamy Sivagurunathan, Arivalagan Pugazhendhi, Gopalakrishnan Kumar, Chang-Su Choi, Sang-Hyoun Kim
This study examined the mesophilic continuous biohydrogen fermentation from galactose and glucose mixture with an initial substrate concentration of 15 g/L (galactose 12 g/L and glucose 3 g/L) as a resembling carbon source of pretreated red algal hydrolyzate. A fixed bed reactor was fed with the sugar mixture at various hydraulic retention times (HRTs) ranging 12 to 1.5 h. The maximum hydrogen production rate of 52.6 L/L-d was found at 2 h HRT, while the maximum hydrogen yield of 2.3±0.1 mol/mol hexoseadded, was achieved at 3 h HRT...
May 18, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28512675/selection-and-characterization-of-an-anaerobic-microbial-consortium-with-high-adaptation-to-crude-glycerol-for-1-3-propanediol-production
#17
Jin-Jie Zhou, Jun-Tao Shen, Li-Li Jiang, Ya-Qin Sun, Ying Mu, Zhi-Long Xiu
Crude glycerol is an ideal feedstock for bioproduction of 1,3-propanediol (1,3-PDO) while pure culture always shows low substrate tolerance and limited productivity. In this study, an anaerobic microbial consortium for conversion of crude glycerol was selected and its 1,3-PDO production capacity was evaluated. The consortium was obtained from anaerobic activated sludge by 19 serial transfers and mainly consisted of 94.64% Clostridiaceae and 4.47% Peptostreptococcaceae. The consortium adapted well with high glycerol concentration of 120 g/L as well as wide substrate concentration fluctuation from 15 to 80 g/L, producing 60...
May 16, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28478805/clostridium-butyricum-partially-regulates-the-development-of-colitis-associated-cancer-through-mir-200c
#18
Y Xiao, X Dai, K Li, G Gui, J Liu, H Yang
Colitis-associated cancer (CAC), one form of colorectal cancer (CRC),is an increasing concern worldwide. Both diagnosis and current therapy are challenging and bottlenecked. The aim of this study is to investigate novel mechanisms by which the therapeutic C. butyricum regulates colitis-induced oncogenesis. Mouse models of CAC were established with 2,4,6-Trinitrobenzenesulfonic acid (TNBS)and azoxymethane (AOM), following by biochemical, clinical and histological analysis. The integrity of epitheliumwas examined by electron microscopy (EM)...
April 29, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28374597/-foodborne-botulism-a-re-emerging-public-health-challenge
#19
R Mezencev, C Klement
Human foodborne botulism is an intoxication caused by ingestion of botulinum neurotoxins (BoNT) of serotypes A, B, E, and rarely also serotype F, produced in contaminated food by anaerobic bacteria Clostridium botulinum group I, group II, or by toxigenic strains of C. butyricum and C. baratii. BoNT-producing Clostridia are ubiquitously distributed in the environment and, under suitable conditions, they can enter the food chain, proliferate and produce BoNT in a variety of foods. In the past, the risk of foodborne botulism was primarily associated with homemade canned foods; however, the epidemiological importance of commercial and restaurant food is increasing nowadays...
2017: Epidemiologie, Mikrobiologie, Imunologie
https://www.readbyqxmd.com/read/28369512/galleria-mellonella-as-an-in-vivo-model-for-assessing-the-protective-activity-of-probiotics-against-gastrointestinal-bacterial-pathogens
#20
Concetta Scalfaro, Angelo Iacobino, Chiara Nardis, Giovanna Franciosa
The antagonistic activity against gastrointestinal bacterial pathogens is an important property of probiotic bacteria and a desirable feature for pre-selection of novel strains with probiotic potential. Pre-screening of candidate probiotics for antibacterial activity should be based on in vitro and in vivo tests. This study investigated whether the protective activity of probiotic bacteria against gastrointestinal bacterial pathogens can be evaluated using Galleria mellonella larvae as an in vivo model. Larvae were pre-inoculated with either of two widely used probiotic bacteria, Lactobacillus rhamnosus GG or Clostridium butyricum Miyairi 588, and then challenged with Salmonella enterica Typhimurium, enteropathogenic Escherichia coli or Listeria monocytogenes...
April 1, 2017: FEMS Microbiology Letters
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