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Clostridium butyricum

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https://www.readbyqxmd.com/read/28539294/-effects-of-clostridium-butyricum-on-serum-uric-acid-and-inflammatory-mediators-in-rats-with-hyperuricemia
#1
Li Wang, Zhi-Rong Fang, Ya-Ting Shen, Yan-Bo Liu, Li-Li Liu
OBJECTIVE: To investigate the effects of intragastric administration of Clostridium butyricum in regulating serum uric acid, lipopolysaccharides (LPS), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in rats with hyperuricemia rats. METHODS: Forty SD rats were randomized into 4 equal groups, namely the normal control group, hyperuricemia model group, benzbromarone (3 mg/kg daily) intervention group and live Clostridium butyricum group (1.5×10(7) CFU/day)...
May 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28536840/insights-from-the-complete-genome-sequence-of-clostridium-tyrobutyricum-provide-a-platform-for-biotechnological-and-industrial-applications
#2
Qian Wu, Tingting Liu, Liying Zhu, He Huang, Ling Jiang
Genetic research enables the evolution of novel biochemical reactions for the production of valuable chemicals from environmentally-friendly raw materials. However, the choice of appropriate microorganisms to support these reactions, which must have strong robustness and be capable of a significant product output, is a major difficulty. In the present study, the complete genome of the Clostridium tyrobutyricum strain CCTCC W428, a hydrogen- and butyric acid-producing bacterium with increased oxidative tolerance was analyzed...
May 23, 2017: Journal of Industrial Microbiology & Biotechnology
https://www.readbyqxmd.com/read/28528789/mixed-culture-h2-fermentation-performance-and-the-relation-between-microbial-community-composition-and-hydraulic-retention-times-for-a-fixed-bed-reactor-fed-with-galactose-glucose-mixtures
#3
Parthiban Anburajan, Jong-Hun Park, Periyasamy Sivagurunathan, Arivalagan Pugazhendhi, Gopalakrishnan Kumar, Chang-Su Choi, Sang-Hyoun Kim
This study examined the mesophilic continuous biohydrogen fermentation from galactose and glucose mixture with an initial substrate concentration of 15 g/L (galactose 12 g/L and glucose 3 g/L) as a resembling carbon source of pretreated red algal hydrolyzate. A fixed bed reactor was fed with the sugar mixture at various hydraulic retention times (HRTs) ranging 12 to 1.5 h. The maximum hydrogen production rate of 52.6 L/L-d was found at 2 h HRT, while the maximum hydrogen yield of 2.3±0.1 mol/mol hexoseadded, was achieved at 3 h HRT...
May 18, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28512675/selection-and-characterization-of-an-anaerobic-microbial-consortium-with-high-adaptation-to-crude-glycerol-for-1-3-propanediol-production
#4
Jin-Jie Zhou, Jun-Tao Shen, Li-Li Jiang, Ya-Qin Sun, Ying Mu, Zhi-Long Xiu
Crude glycerol is an ideal feedstock for bioproduction of 1,3-propanediol (1,3-PDO) while pure culture always shows low substrate tolerance and limited productivity. In this study, an anaerobic microbial consortium for conversion of crude glycerol was selected and its 1,3-PDO production capacity was evaluated. The consortium was obtained from anaerobic activated sludge by 19 serial transfers and mainly consisted of 94.64% Clostridiaceae and 4.47% Peptostreptococcaceae. The consortium adapted well with high glycerol concentration of 120 g/L as well as wide substrate concentration fluctuation from 15 to 80 g/L, producing 60...
May 16, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28478805/clostridium-butyricum-partially-regulates-the-development-of-colitis-associated-cancer-through-mir-200c
#5
Y Xiao, X Dai, K Li, G Gui, J Liu, H Yang
Colitis-associated cancer (CAC), one form of colorectal cancer (CRC),is an increasing concern worldwide. Both diagnosis and current therapy are challenging and bottlenecked. The aim of this study is to investigate novel mechanisms by which the therapeutic C. butyricum regulates colitis-induced oncogenesis. Mouse models of CAC were established with 2,4,6-Trinitrobenzenesulfonic acid (TNBS)and azoxymethane (AOM), following by biochemical, clinical and histological analysis. The integrity of epitheliumwas examined by electron microscopy (EM)...
April 29, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28374597/-foodborne-botulism-a-re-emerging-public-health-challenge
#6
R Mezencev, C Klement
Human foodborne botulism is an intoxication caused by ingestion of botulinum neurotoxins (BoNT) of serotypes A, B, E, and rarely also serotype F, produced in contaminated food by anaerobic bacteria Clostridium botulinum group I, group II, or by toxigenic strains of C. butyricum and C. baratii. BoNT-producing Clostridia are ubiquitously distributed in the environment and, under suitable conditions, they can enter the food chain, proliferate and produce BoNT in a variety of foods. In the past, the risk of foodborne botulism was primarily associated with homemade canned foods; however, the epidemiological importance of commercial and restaurant food is increasing nowadays...
2017: Epidemiologie, Mikrobiologie, Imunologie
https://www.readbyqxmd.com/read/28369512/galleria-mellonella-as-an-in-vivo-model-for-assessing-the-protective-activity-of-probiotics-against-gastrointestinal-bacterial-pathogens
#7
Concetta Scalfaro, Angelo Iacobino, Chiara Nardis, Giovanna Franciosa
The antagonistic activity against gastrointestinal bacterial pathogens is an important property of probiotic bacteria and a desirable feature for pre-selection of novel strains with probiotic potential. Pre-screening of candidate probiotics for antibacterial activity should be based on in vitro and in vivo tests. This study investigated whether the protective activity of probiotic bacteria against gastrointestinal bacterial pathogens can be evaluated using Galleria mellonella larvae as an in vivo model. Larvae were pre-inoculated with either of two widely used probiotic bacteria, Lactobacillus rhamnosus GG or Clostridium butyricum Miyairi 588, and then challenged with Salmonella enterica Typhimurium, enteropathogenic Escherichia coli or Listeria monocytogenes...
April 1, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28359948/effect-of-dietary-clostridium-butyricum-on-growth-intestine-health-status-and-resistance-to-ammonia-stress-in-pacific-white-shrimp-litopenaeus-vannamei
#8
Yafei Duan, Yue Zhang, Hongbiao Dong, Yun Wang, Xiaoting Zheng, Jiasong Zhang
The present study evaluated the effect of dietary Clostridium butyricum (CB) on growth, intestine microstructure, intestine digestive and immune function, intestine short-chain fatty acids (SCFA) content and body composition of Pacific white shrimp Litopenaeus vannamei. The shrimp was fed for 56 d with diets containing different levels of C. butyricum (1 × 10(9) cfu/g): 0% (Control), 0.25% (CB1), 0.5% (CB2) and 1.0% (CB3) as treatment groups, followed by an acute ammonia stress test for 72 h. The results indicated that dietary supplementation of C...
March 27, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28330087/decolorization-and-biodegradation-of-remazol-reactive-dyes-by-clostridium-species
#9
Sanmuga Priya Ekambaram, Senthamil Selvan Perumal, Umayal Annamalai
Decolorisation and biodegradation efficacy of potential strains isolated from dyeing effluent collected from Tirupur region, Tamil Nadu, India were studied in remazol reactive dyes. Two potential strains Clostridium butyricum (EI05) and Clostridium acetobutylicum (EI25) identified by biochemical tests in our previous study were studied for their decolorising efficiency on various remazol reactive dyes (Remazol Blue RGB, Remazol Blue RR, Remazol Navy RGB and Remazol Orange RR). The synthetic dyes showed complete decolorization after 24-72 h by two potential strains EI05 and EI25...
June 2016: 3 Biotech
https://www.readbyqxmd.com/read/28285221/preeminent-productivity-of-1-3-propanediol-by-clostridium-butyricum-jkt37-and-the-role-of-using-calcium-carbonate-as-ph-neutraliser-in-glycerol-fermentation
#10
Zhao Kang Tee, Jamaliah Md Jahim, Jian Ping Tan, Byung Hong Kim
Calcium carbonate was evaluated as a replacement for the base during the fermentation of glycerol by a highly productive strain of 1,3-propanediol (PDO), viz., Clostridium butyricum JKT37. Due to its high specific growth rate (µmax=0.53h(-1)), 40g/L of glycerol was completely converted into 19.6g/L of PDO in merely 7h of batch fermentation, leaving only acetate and butyrate as the by-products. The accumulation of these volatile fatty acids was circumvented with the addition of calcium carbonate as the pH neutraliser before the fermentation was inoculated...
March 1, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28256808/farm-level-survey-of-spore-forming-bacteria-on-four-dairy-farms-in-the-waikato-region-of-new-zealand
#11
Tanushree B Gupta, Gale Brightwell
The aim of our study was to determine the occurrence and diversity of economically important spore-forming bacteria in New Zealand dairy farm systems. Farm dairy effluent (FDE) collected from Waikato dairy farms were tested for the presence of spore-forming bacteria, using a new culture-based methodology followed by genomic analysis. An enrichment step in which samples were inoculated in cooked meat glucose starch broth under anaerobic conditions, aided in the differential isolation of Bacillus and Clostridium species...
March 3, 2017: MicrobiologyOpen
https://www.readbyqxmd.com/read/28250847/oral-administration-of-clostridium-butyricum-cgmcc0313-1-inhibits-%C3%AE-lactoglobulin-induced-intestinal-anaphylaxis-in-a-mouse-model-of-food-allergy
#12
Juan Zhang, Hui Su, Qiuhong Li, Haixia Wu, Mengyun Liu, Jianqiong Huang, Minghua Zeng, Yuejie Zheng, Xin Sun
BACKGROUND: Probiotic bacteria can induce immune regulation or immune tolerance in patients with allergic diseases, but the underlying mechanisms are still unclear. There has been a growing interest in the use of beneficial bacteria for allergic diseases recently. This study aimed at exploring whether Clostridium butyricum CGMCC0313-1 (C. butyricum) can reduce β-lactoglobulin(BLG)-induced intestinal anaphylaxis in a murine model of food allergy. METHODS: The preventive and therapeutic effects of oral C...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/28122397/oral-administration-of-clostridium-butyricum-cgmcc0313-1-reduces-ovalbumin-induced-allergic-airway-inflammation-in-mice
#13
Zhang Juan, Shi Zhao-Ling, Zeng Ming-Hua, Wei Chun, Wu Hai-Xia, Liu Meng-Yun, Huang Jian-Qiong, Zheng Yue-Jie, Sun Xin
BACKGROUND AND OBJECTIVE: Probiotic bacteria can induce immune regulation or immune tolerance in patients with allergic diseases, but the underlying mechanisms are still unclear. There has been a growing interest in the use of beneficial bacteria for allergic diseases recently. This study aimed at exploring whether Clostridium butyricum CGMCC0313-1 (C. butyricum) can reduce ovalbumin (OVA)-induced allergic airway inflammation in a mouse model. METHODS: Mouse model of allergic airway inflammation induced via OVA was used in this study...
January 25, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28119466/effects-of-the-dietary-protein-and-carbohydrate-ratio-on-gut-microbiomes-in-dogs-of-different-body-conditions
#14
Qinghong Li, Christian L Lauber, Gail Czarnecki-Maulden, Yuanlong Pan, Steven S Hannah
Obesity has become a health epidemic in both humans and pets. A dysbiotic gut microbiota has been associated with obesity and other metabolic disorders. High-protein, low-carbohydrate (HPLC) diets have been recommended for body weight loss, but little is known about their effects on the canine gut microbiome. Sixty-three obese and lean Labrador retrievers and Beagles (mean age, 5.72 years) were fed a common baseline diet for 4 weeks in phase 1, followed by 4 weeks of a treatment diet, specifically, the HPLC diet (49...
January 24, 2017: MBio
https://www.readbyqxmd.com/read/28111775/effects-of-synbiotic-supplementation-on-growth-performance-carcass-characteristics-meat-quality-and-muscular-antioxidant-capacity-and-mineral-contents-in-broilers
#15
Yefei Cheng, Yueping Chen, Xiaohan Li, Weili Yang, Chao Wen, Yuru Kang, Aiqin Wang, Yanmin Zhou
BACKGROUND: The present study aimed to investigate the effects of dietary synbiotic supplementation on growth performance, carcass composition, meat quality and muscular antioxidant capacity, and mineral contents in broilers. Accordingly, 96 day-old male broiler chicks (Arbor Acres Plus; Aviagen, Huntsville, AL, USA) were randomly allocated to two groups, and each group consisted of six replicates with eight chicks each. Birds were fed a corn-soybean meal basal diet supplemented with either 0 or 1...
January 23, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28109017/clostridium-butyricum-b1-alleviates-high-fat-diet-induced-steatohepatitis-in-mice-via-enterohepatic-immunoregulation
#16
Da Zhou, Qin Pan, Xiao-Lin Liu, Rui-Xu Yang, Yuan-Wen Chen, Chang Liu, Jian-Gao Fan
BACKGROUND AND AIM: Enterohepatic immunologic derangement is associated with nonalcoholic steatohepatitis (NASH). Here, we investigated whether Clostridium butyricum B1 (CB) would be an effective immune-targeted substance to attenuate steatohepatitis in mice. METHODS: Thirty mice were randomized into a control group fed with common forage, a high-fat diet (HFD) group fed a HFD for 16 weeks, and a HFD + CB group treated with CB for the latter 8 weeks. Inflammation- or metabolism-associated genes in the liver or epididymal fat tissue were quantified, intrahepatic and intestinal immune factors were detected...
January 20, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28025221/bacteria-associated-with-piezodorus-guildinii-hemiptera-pentatomidae-with-special-reference-to-those-transmitted-by-feeding
#17
Claudia Husseneder, Jong-Seok Park, Andrea Howells, Chinmay V Tikhe, Jeffrey A Davis
The redbanded stink bug, Piezodorus guildinii (Westwood) (Hemiptera: Heteroptera: Pentatomidae), is a rapidly growing pest damaging southern US agriculture. Pentatomid stink bugs are known to vector bacterial, fungal, and viral plant diseases. However, bacteria associated with redbanded stink bugs and their vector potential have not yet been assessed. In this study, we 1) cultured and identified bacteria transmitted by feeding of redbanded stink bug and 2) described bacteria from guts of redbanded stink bug individuals using next-generation sequencing of 16S rRNA genes...
February 1, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/27988045/multi-spacer-typing-as-an-effective-method-to-distinguish-the-clonal-lineage-of-clostridium-butyricum-strains-isolated-from-stool-samples-during-a-series-of-necrotizing-enterocolitis-cases
#18
S Benamar, N Cassir, V Merhej, P Jardot, C Robert, D Raoult, B La Scola
BACKGROUND: Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease with high morbidity and mortality that predominantly affects preterm neonates during outbreaks. In a previous study, the present authors identified 15 Clostridium butyricum isolates from stool samples during a series of NEC cases involving four neonatal intensive care units. A clonal lineage of these strains was observed by in-silico multi-locus sequence typing. AIM: To confirm the previous findings by sequencing a larger number of C...
March 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27914813/normal-human-gingival-fibroblasts-undergo-cytostasis-and-apoptosis-after-long-term-exposure-to-butyric-acid
#19
Michihiro Shirasugi, Keisuke Nishioka, Toshiro Yamamoto, Takaaki Nakaya, Narisato Kanamura
The causes of periodontal disease are complex. Butyric acid, a metabolite of periodontopathic bacteria such as Porphyromonas gingivalis, acts as a histone deacetylase inhibitor that has a direct effect on mRNA expression. Butyric acid produced by Clostridium butyricum in the intestinal tract induces differentiation of regulatory T cells, thereby suppressing inflammation in the gut. Mice lacking Clostridium butyricum in the intestinal tract suffer from colitis. By contrast, butyric acid in the oral cavity worsens periodontal disease...
January 22, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27698538/vitamin-a-deficiency-impacts-the-structural-segregation-of-gut-microbiota-in-children-with-persistent-diarrhea
#20
Zeyu Lv, Yuting Wang, Ting Yang, Xue Zhan, Zhongyue Li, Huajian Hu, Tingyu Li, Jie Chen
To investigate whether gut microbiota is associated with vitamin A nutritional levels in children with persistent diarrhea, a total of 59 pediatric patients with persistent diarrhea aged 1-12 months were selected from the Department of Gastroenterology at the Children's Hospital of Chongqing Medical University, China. Subjects were hospitalized and divided into VA-deficient (n = 30) and VA-normal (n = 29) groups according to their venous serum retinol levels. Fecal samples from all 59 subjects were collected immediately after admission and analyzed by Illumina MiSeq for 16S rRNA genes to characterize the overall microbiota of the samples...
September 2016: Journal of Clinical Biochemistry and Nutrition
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