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https://www.readbyqxmd.com/read/28623275/influences-of-temperature-and-salinity-on-physicochemical-properties-and-toxicity-of-zinc-oxide-nanoparticles-to-the-marine-diatom-thalassiosira-pseudonana
#1
Mana M N Yung, Kevin W H Kwok, Aleksandra B Djurišić, John P Giesy, Kenneth M Y Leung
Climate change is predicted to result in rising average temperature of seawater with more extreme thermal events, and frequent rainfalls in some coastal regions. It is imperative to understand how naturally mediated changes in temperature and salinity can modulate toxicity of chemical contaminants to marine life. Thus, this study investigated combined effects of temperature and salinity on toxicity of zinc oxide nanoparticles (ZnO-NPs) to the marine diatom Thalassiosira pseudonana. Because ZnO-NPs formed larger aggregations and released less zinc ions (Zn(2+)) at greater temperature and salinity, toxicity of ZnO-NPs to T...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28623151/cognitive-performance-across-3-frailty-phenotypes-toledo-study-for-healthy-aging
#2
Cristina Rosado-Artalejo, Jose Antonio Carnicero, Jose Losa-Reyna, Amelia Guadalupe-Grau, Carmen Castillo-Gallego, Gonzalo Gutierrez-Avila, Ana Alfaro-Acha, Fernando Rodríguez-Artalejo, Leocadio Rodríguez-Mañas, Francisco José García-García
INTRODUCTION: Frailty is a strong predictor of adverse health events, but its impact on cognitive function is poorly understood. AIM: To assess cognitive performance in frailty and to identify the frailty stage where cognitive impairment begins. METHODS: Data were taken from 2044 people aged ≥65 years without cognitive impairment selected from the Toledo Study for Healthy Aging, a population-based cohort of older adults. Frailty status was assessed by 3 different scales: Frailty Phenotype (FP), Frailty Trait Scale (FTS), and Frailty Index (FI)...
June 13, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28621277/botulinum-toxin-for-the-treatment-of-gummv-smile
#3
Afnan F Al-Fouzan, Lamia S Mokeem, Reem T Al-Saqat, Maisa A Alfalah, Mana A Alharbi, Abdullah E Al-Samary
AIM: The aim was to evaluate the effect of botulinum toxin (Botox) injections as a conservative treatment for gummy smile. MATERIALS AND METHODS: An experimental in vivo study was conducted at a dermatology clinic in Riyadh in January 2016. The study included 23 female patients who ranged from 20 to 50 years and were treated with Botox injections due to excessive maxillary gingival display. The patients with short clinical crowns or long maxilla, those who were pregnant or breastfeeding, and patients with neuromuscular disorders were excluded...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28617439/cdc20-directs-proteasome-mediated-degradation-of-the-tumor-suppressor-smar1-in-higher-grades-of-cancer-through-the-anaphase-promoting-complex
#4
Debasish Paul, Suvankar Ghorai, U S Dinesh, Praveenkumar Shetty, Samit Chattopadhyay, Manas Kumar Santra
The Tumor suppressor SMAR1 (scaffold matrix attachment region binding protein 1) has a crucial role in maintaining genomic stability, cell cycle progression and apoptosis.Our previous finding showed that it is highly suppressed in higher grade of cancer. However, the underlying mechanism of this suppression was not well understood. In this study, we show that SMAR1 expression levels are controlled at the proteasomal level by five RING finger E3 ubiquitin ligases including, Cdc20, a substrate receptor of ubiquitin ligase APC/C complex...
June 15, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28613075/syntheses-of-tetrahydrobenzoazepinoindoles-and-dihydrobenzodiazepinoindoles-via-ring-opening-cyclization-of-activated-aziridines-with-2-2-bromophenyl-1h-indoles
#5
Sajan Pradhan, Chandan Kumar Shahi, Aditya Bhattacharyya, Navya Chauhan, Manas K Ghorai
Two efficient, modular, step- and pot-economic strategies to access various 5,6,7,12-tetrahydrobenzo[2,3]azepino[4,5-b]indoles and 6,7-dihydro-5H-benzo[5,6][1,4]diazepino[1,7-a]indoles are disclosed that advance via SN2-type regioselective ring opening of enantiopure aziridines with 2-(2-bromophenyl)-1H-indoles at their C3 and indolyl N centers, respectively, followed by Cu-mediated C-N cyclization which furnishes the products in excellent yields with outstanding enantiomeric excesses (up to >99%).
June 14, 2017: Organic Letters
https://www.readbyqxmd.com/read/28611437/reproductive-isolation-through-experimental-manipulation-of-sexually-antagonistic-coevolution-in-drosophila-melanogaster
#6
Zeeshan Ali Syed, Martik Chatterjee, Manas Arun Samant, Nagaraj Guru Prasad
Promiscuity can drive the evolution of sexual conflict before and after mating occurs. Post mating, the male ejaculate can selfishly manipulate female physiology, leading to a chemical arms race between the sexes. Theory suggests that drift and sexually antagonistic coevolution can cause allopatric populations to evolve different chemical interactions between the sexes, thereby leading to postmating reproductive barriers and speciation. There is, however, little empirical evidence supporting this form of speciation...
June 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28610121/a-new-species-of-velvet-skate-i-notoraja-i-i-sereti-i-n-sp-rajiformes-arhynchobatidae-from-papua-new-guinea
#7
William T White, Peter R Last, Ralph R Mana
A new arhynchobatin skate, Notoraja sereti n. sp., is described based on three specimens collected from off Madang (Papua New Guinea) at depths of 800-980 m. This medium-size Notoraja skate shares with other velcro skates from the Western Pacific, N. alisae, N. fijiensis, N. inusitata and N. longiventralis, a ventral surface covering of fine denticles giving the skin a velvety feel. Notoraja sereti differs from all of these species in having a shorter snout (preorbital length 10.1-11.1 vs. 11.5-14.5% TL, prenasal length 8...
March 19, 2017: Zootaxa
https://www.readbyqxmd.com/read/28610109/-i-etmopterus-i-i-samadiae-i-n-sp-a-new-lanternshark-squaliformes-etmopteridae-from-papua-new-guinea
#8
William T White, David A Ebert, Ralph R Mana, Shannon Corrigan
A new species of lanternshark, Etmopterus samadiae (Squaliformes: Etmopteridae), is described from off northern Papua New Guinea, in the western Central Pacific Ocean. The new species resembles other members of the "Etmopterus lucifer" clade in having linear rows of dermal denticles and most closely resembles E. brachyurus from the western North Pacific. The new species occurs along insular slopes between 340 and 785 m depth. The new species can be distinguished from other members of the E. lucifer clade by a combination of characteristics, including length of anterior flank branch markings being slightly shorter than its posterior branch, a longer caudal base marking, and irregular and variable number of black, horizontal, dash-like marks on sides of body...
March 20, 2017: Zootaxa
https://www.readbyqxmd.com/read/28607850/interpositional-lateral-thoracic-vein-graft-for-diep-flap-salvage-in-setting-of-superficial-venous-system-dominance
#9
Manas Nigam, Michael V DeFazio, Maurice Y Nahabedian
No abstract text is available yet for this article.
May 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28602428/influence-of-amalaki-rasayana-on-telomerase-activity-and-telomere-length-in-human-blood-mononuclear-cells
#10
Kanive P Guruprasad, Sweta Dash, Marigowda B Shivakumar, Pavithra R Shetty, Kothanahalli S Raghu, Bhanuvalli R Shamprasad, Vishwanatha Udupi, Raviraj V Acharya, Prasanna B Vidya, Jayakrishna Nayak, Anandan E Mana, Rajesh Moni, Muraleedharan T Sankaran, Kapaettu Satyamoorthy
BACKGROUND: Indian traditional medicine practices use defined rasayana preparations to improve the quality of health in aged individuals. Amalaki Rasayana is one such rasayana prepared from the fruits of Phyllanthus emblica and is popularly used to prevent or treat various age related health conditions. Telomerase activity in the cells maintains telomere length and is implicated in ageing and various diseases wherein the shortening of telomere during ageing is controlled chiefly by the telomerase activity...
June 8, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28599703/cellular-neurothakeoma-in-a-relatively-rare-site
#11
Manas Bajpai, Nilesh Pardhe
No abstract text is available yet for this article.
May 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28595963/frailty-what-are-we-talking-about-implications-for-the-daily-clinical-practice
#12
Leocadio Rodríguez-Mañas, Jeremy D Walston
No abstract text is available yet for this article.
June 5, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28594468/application-of-an-advanced-maximum-likelihood-estimation-restoration-method-for-enhanced-resolution-and-contrast-in-second-harmonic-generation-microscopy
#13
Mayandi Sivaguru, Mohammad M Kabir, Manas Rangan Gartia, David S C Biggs, Barghav S Sivaguru, Vignesh A Sivaguru, Glenn A Fried, Gang Logan Liu, Sakthivel Sadayappan, Kimani C Toussaint
Second-harmonic generation (SHG) microscopy has gained popularity because of its ability to perform submicron, label-free imaging of noncentrosymmetric biological structures, such as fibrillar collagen in the extracellular matrix environment of various organs with high contrast and specificity. Because SHG is a two-photon coherent scattering process, it is difficult to define a point spread function (PSF) for this modality. Hence, compared to incoherent two-photon processes like two-photon fluorescence, it is challenging to apply the various PSF-engineering methods to improve the spatial resolution to be close to the diffraction limit...
June 8, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28593077/alteration-in-leukocyte-subsets-and-expressions-of-fc%C3%AE-r-and-complement-receptors-among-female-ragpickers-in-eastern-india
#14
Nandan K Mondal, Shabana Siddique, Madhuchanda Banerjee, Sanghita Roychoudhury, Sayali Mukherjee, Mark S Slaughter, Twisha Lahiri, Manas R Ray
BACKGROUND: There are a million ragpickers in India who gather and trade recyclable municipal solid wastes materials for a living. The objective of this study was to examine whether their occupation adversely affects their immunity. METHODS: Seventy-four women ragpickers (median age, 30 years) and 65 age-matched control housemaids were enrolled. Flow cytometry was used to measure leukocyte subsets, and leukocyte expressions of Fcγ receptor I (CD64), FcγRIII (CD16), complement receptor 1 (CD35) and CR3 (CD11b/CD18), and CD14...
June 2017: Safety and Health At Work
https://www.readbyqxmd.com/read/28592164/what-did-latino-family-caregivers-expect-and-learn-from-education-intervention-caregivers-like-me
#15
Dulce M Cruz-Oliver, Manas Parikh, Cara L Wallace, Theodore K Malmstrom, Sandra Sanchez-Reilly
OBJECTIVE: US Latinos historically have underutilized end-of-life (EOL) resources. This study reports the views of family caregivers before and after education intervention Caregivers Like Me geared to improve knowledge and attitudes regarding EOL resources among Latino caregivers. METHODS: This is a qualitative substudy within a multicentered cross-sectional study design. Educational intervention was offered to family caregivers of Latino elders from 3 different communities, using an audiovisual presentation, including a case-based video telenovela and pre-posttest questionnaires with open-ended questions...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/28591763/non-linear-formation-of-etg-and-faees-after-controlled-administration-of-low-to-moderate-doses-of-ethanol
#16
Clara Pérez-Mañá, Magí Farré, Antoni Pastor, Francina Fonseca, Marta Torrens, Esther Menoyo, Mitona Pujadas, Silvia Frias, Klaus Langohr, Rafael de la Torre
Aims: Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) are non-oxidative metabolites of alcohol that can be detected in conventional and non-conventional biological matrices for longer periods than alcohol. The aim was to describe the time courses of both biomarkers after ingestion of acute low-moderate doses of ethanol. Methods: The study design was double-blind, randomized, crossover and controlled with placebo. Participants were distributed in three different cohorts: (a) Cohort-1: two doses of 18 and 30 g of ethanol and placebo were administered to 12 subjects; (b) Cohort-2: two doses of 6 and 12 g of ethanol and placebo were administered to six subjects and (c) Cohort-3: two doses of 24 and 42 g of ethanol and placebo were administered to six subjects...
June 7, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28591200/correction-use-of-molecular-markers-in-identification-and-characterization-of-resistance-to-rice-blast-in-india
#17
Manoj Kumar Yadav, Aravindan S, Umakanta Ngangkham, H N Subudhi, Manas Kumar Bag, Totan Adak, Sushmita Munda, Sanghamitra Samantaray, Mayabini Jena
[This corrects the article DOI: 10.1371/journal.pone.0176236.].
2017: PloS One
https://www.readbyqxmd.com/read/28590112/impurities-in-a-28-si-enriched-single-crystal-produced-for-the-realization-of-the-redefined-kilogram
#18
Marco Di Luzio, Attila Stopic, Giancarlo D'Agostino, John W Bennett, Giovanni Mana, Massimo Oddone
The practical realization of the unit of mass is possible by manufacturing a perfect one-kilogram sphere from a (28)Si-enriched single crystal. The mass of the sphere can be determined in terms of a fixed value of the Planck constant by counting the number of silicon atoms in the core of the single crystal. To reach the target 2.0 × 10(-8) relative standard uncertainty, the mass of the surface layer and the mass deficit due to point defects such as impurities and vacancies must be investigated and corrected for...
June 9, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28587625/anti-nuclear-autoantibodies-in-the-general-german-population-prevalence-and-lack-of-association-with-selected-cardiovascular-and-metabolic-disorders-findings-of-a-multicenter-population-based-study
#19
Manas K Akmatov, Nadja Röber, Wolfgang Ahrens, Dieter Flesch-Janys, Julia Fricke, Halina Greiser, Kathrin Günther, Rudolf Kaaks, Yvonne Kemmling, Bastian Krone, Jakob Linseisen, Christa Meisinger, Susanne Moebus, Nadia Obi, Carlos A Guzman, Karsten Conrad, Frank Pessler
BACKGROUND: We determined the prevalence of anti-nuclear autoantibodies (ANAs) in the German adult population and examined the association between ANAs and cardiovascular and metabolic disorders. METHODS: We used data and blood samples from the pretest phases of the German National Cohort, obtained from six of the 18 study centers (n = 1199). All centers applied standardized instruments including face-to-face interviews, anthropometric measurements and collection of blood samples...
June 6, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28585770/mining-the-proteome-of-leishmania-donovani-for-the-development-of-novel-mhc-class-i-restricted-epitope-for-the-control-of-visceral-leishmaniasis
#20
Manas R Dikhit, Vijay Mahantesh, Akhilesh Kumar, Ajay Amit, Budheswar Dehury, Yangya Prasad Nathsharma, Md Yousuf Ansari, Vahab Ali, Roshan Kamal Topno, Vnr Das, Krishna Pandey, Ganesh Chandra Sahoo, Sanjiva Bimal, Pradeep Das
Although, the precise host defence mechanism(s) is not completely understood, T cell-mediated immune responses is believed to play a pivotal role in controlling parasite infection. Here we target the stage dependent over expressed gene. Here, the consensus based computational approach was adopted for the screening of potential major histocompatibility complex class I restricted epitopes. Based on the computational analysis and previously published report, a set 19 antigenic proteins derived from Leishmania donovani were screened for further characterization as vaccine candidates...
June 6, 2017: Journal of Cellular Biochemistry
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