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https://www.readbyqxmd.com/read/29917252/comparison-of-complications-between-peripheral-arm-ports-and-central-chest-ports-a-meta-analysis
#1
REVIEW
Shanshan Wu, Wanjiao Li, Qiongxiao Zhang, Shuting Li, Lizi Wang
AIM: To compare peripheral arm ports versus central chest ports in complication rates. BACKGROUND: Late complications of arm ports versus chest ports, including catheter-related infection, venous thrombosis and catheter obstruction, remain controversial. DESIGN: A meta-analysis conducted following the Cochrane handbook. DATA SOURCES: Studies published between 1950 - August 2017 were searched through Pubmed, Embase, Web of science and Cochrane library...
June 19, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29915057/human-induced-pluripotent-stem-cell-derived-glial-cells-and-neural-progenitors-display-divergent-responses-to-zika-and-dengue-infections
#2
Julien Muffat, Yun Li, Attya Omer, Ann Durbin, Irene Bosch, Grisilda Bakiasi, Edward Richards, Aaron Meyer, Lee Gehrke, Rudolf Jaenisch
Maternal Zika virus (ZIKV) infection during pregnancy is recognized as the cause of an epidemic of microcephaly and other neurological anomalies in human fetuses. It remains unclear how ZIKV accesses the highly vulnerable population of neural progenitors of the fetal central nervous system (CNS), and which cell types of the CNS may be viral reservoirs. In contrast, the related dengue virus (DENV) does not elicit teratogenicity. To model viral interaction with cells of the fetal CNS in vitro, we investigated the tropism of ZIKV and DENV for different induced pluripotent stem cell-derived human cells, with a particular focus on microglia-like cells...
June 18, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29914598/interventions-to-improve-adherence-to-tuberculosis-treatment-systematic-review-and-meta-analysis
#3
A M Müller, C S Osório, D R Silva, G Sbruzzi, P de Tarso, Roth Dalcin
SETTING: One of the most serious problems in tuberculosis (TB) control is non-adherence to treatment. Several strategies have been developed to improve adherence and increase the cure rate. OBJECTIVE: To systematically review interventions to improve adherence to anti-tuberculosis treatment. DESIGN: We performed a systematic review and meta-analysis of 22 randomised clinical trials (RCTs) to ascertain whether providing directly observed treatment, short-course (DOTS), financial incentives, food incentives and/or patient education/counselling improved adherence to anti-tuberculosis treatment...
July 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29913024/laser-pointer-induced-maculopathy-more-than-meets-the-eye
#4
Kamal Mtanes, Michael Mimouni, Shiri Zayit-Soudry
PURPOSE: To describe the clinical findings in patients with laser-induced retinal injury. METHODS: Consecutive patients presenting to a tertiary center between January 2014 and December 2015 following inadvertent ocular exposure to a laser pointer were included. Evaluation included a full ophthalmic examination and spectral-domain optical coherence tomography (SD-OCT). RESULTS: Seven young patients (8 eyes) were identified. Their mean age was 18...
June 18, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29912975/an-experimental-study-does-inbreeding-increase-the-motivation-to-mate
#5
Raïssa A de Boer, Marcel Eens, Wendt Müller
Inbreeding is a central topic in evolutionary biology and ecology and is of major concern for the conservation of endangered species. Yet, it remains challenging to comprehend the fitness consequences of inbreeding, because studies typically focus only on short-term effects on inbreeding in the offspring (e.g. survival until independence). However, there is no a priori reason to assume that inbreeding has no more effects in adulthood. Specifically, inbred males should have lower reproductive success than outbred males among other things because of inbreeding depression in attractiveness to females and a reduced lifespan...
2018: PloS One
https://www.readbyqxmd.com/read/29912752/assessing-quality-of-precut-sphincterotomy-in-patients-with-difficult-biliary-access-an-updated-meta-analysis-of-randomized-controlled-trials
#6
Jie Chen, Jian Hua Wan, Dang Yan Wu, Wen Qing Shu, Liang Xia, Nong Hua Lu
BACKGROUND: It is generally accepted that precut sphincterotomy during endoscopic retrograde cholangiopancreatography (ERCP) increases the risk of pancreatitis. However, patients with difficult biliary access may be different. We implemented a meta-analysis to explore the effects of early and delayed precut sphincterotomy on post-ERCP pancreatitis in patients with difficult biliary access. METHODS: We searched studies in PubMed, EMBASE, and the Cochrane Central Register of Randomized Controlled Trials for meeting requirement in which precut sphincterotomy was compared with persistent standard cannulation during ERCP...
June 16, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29911010/three-dimensional-transesophageal-echocardiographic-diagnosis-of-catheter-endocarditis-hidden-in-intracaval-stent
#7
Rita Leonarda Musci, Cataldo Girasoli, Fabrizio Fumarola, Carlo D'Agostino, Paolo Colonna
In recent years, with an increasing number of central venous access procedures and cardiac implantable electronic device implantation, the incidence of infective endocarditis (IE) has become more prevalent. Two-dimensional transthoracic echocardiography (2D-TTE) and transesophageal echocardiography (TEE) are a key part of the evaluation of IE, but advances in three-dimensional echocardiography have enabled a better spatial resolution and visualization of cardiac structures, allowing the identification of any valvular vegetations, abscesses, or nodules...
April 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29910186/structural-basis-of-phosphatidic-acid-sensing-by-aph-in-apicomplexan-parasites
#8
Nick Darvill, David J Dubois, Sarah L Rouse, Pierre-Mehdi Hammoudi, Tom Blake, Stefi Benjamin, Bing Liu, Dominique Soldati-Favre, Steve Matthews
Plasmodium falciparum and Toxoplasma gondii are obligate intracellular parasites that belong to the phylum of Apicomplexa and cause major human diseases. Their access to an intracellular lifestyle is reliant on the coordinated release of proteins from the specialized apical organelles called micronemes and rhoptries. A specific phosphatidic acid effector, the acylated pleckstrin homology domain-containing protein (APH) plays a central role in microneme exocytosis and thus is essential for motility, cell entry, and egress...
May 23, 2018: Structure
https://www.readbyqxmd.com/read/29907994/statistical-enhancement-of-lipase-extracellular-production-by-bacillus-stratosphericus-psp8-in-a-batch-submerged-fermentation-process
#9
Abdallah R Ismail, Samy B El-Henawy, Sherif A Younis, Mohamed A Betiha, Nour Sh El-Gendy, Mohamed S Azab, Nagwa M Sedky
THE AIM: of this study was to isolate and identify lipolytic bacteria. Perform a statistical stepwise physicochemical optimization for maximum production of extracellular lipase and its validation in a bioreactor. METHODS AND RESULTS: Several lipolytic bacteria were isolated from petroleum hydrocarbon polluted soil. The strain expressing the highest lipase activity (47 U ml-1 ) was genetically identified as Gram +ve Bacillus stratosphericus PSP8 (NCBI GenBank Accession no...
June 16, 2018: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29904773/double-transition-metal-mxenes-with-wide-band-gaps-and-novel-magnetic-properties
#10
Weiwei Sun, Yu Xie, Paul R C Kent
Novel wide band gaps and magnetism in ordered titanium-vanadium, titanium-chromium, and titanium-manganese carbide and nitride based MXenes are predicted using density functional theory. Based on the recent synthesis of Ti centred double transition metal MXenes, we study MXenes with a central Ti layer and different surface early 3d metals, and various terminations, TiM2X2T (M = V, Cr, Mn; X = C, N; T = H, F, O, OH). While previously studied MXenes are strongly metallic, we predict surface metal and termination dependent metal-insulator transitions in the Cr-N and Mn-N series...
June 15, 2018: Nanoscale
https://www.readbyqxmd.com/read/29904730/surveillance-and-epidemiology-of-drug-resistant-infections-consortium-sedric-supporting-the-transition-from-strategy-to-action
#11
Keiji Fukuda, Direk Limmathurotsakul, Iruka N Okeke, Nandini Shetty, Rogier van Doorn, Nicholas A Feasey, Francesca Chiara, Ghada Zoubiane, Tim Jinks, Julian Parkhill, Jean Patel, Stuart W J Reid, Alison H Holmes, Sharon J Peacock
In recognition of the central importance of surveillance and epidemiology in the control of antimicrobial resistance and the need to strengthen surveillance at all levels, Wellcome has brought together a new international expert group SEDRIC (Surveillance and Epidemiology of Drug Resistant Infections Consortium). SEDRIC aims to advance and transform the ways of tracking, sharing and analysing rates of infection and drug resistance, burden of disease, information on antibiotic use, opportunities for preventative measures such as vaccines, and contamination of the environment...
2018: Wellcome Open Research
https://www.readbyqxmd.com/read/29904531/fostering-conversation-about-synthetic-biology-between-publics-and-scientists-a-comparison-of-approaches-and-outcomes
#12
Katie Todd, Gretchen Haupt, Elizabeth Kunz Kollmann, Sarah Pfeifle
Public engagement with science (PES) is an emerging outreach method that builds trust between scientists and public audiences by encouraging two-way conversations and mutual learning about science content and societal values. Building with Biology, a PES initiative focused on synthetic biology, distributed 182 kits with two types of products to informal science education institutions across the United States: 1) hands-on activities for public events, and 2) materials to run public dialogue programs, called forums...
2018: Journal of Microbiology & Biology Education: JMBE
https://www.readbyqxmd.com/read/29903796/should-women-aged-70-74-be-invited-to-participate-in-screening-mammography-a-report-on-two-australian-community-juries
#13
Chris Degeling, Alexandra Barratt, Sanchia Aranda, Robin Bell, Jenny Doust, Nehmat Houssami, Jolyn Hersch, Ruben Sakowsky, Vikki Entwistle, Stacy M Carter
OBJECTIVE: To elicit informed views from Australian women aged 70-74 regarding the acceptability of ceasing to invite women their age to participate in government-funded mammography screening (BreastScreen). DESIGN: Two community juries held in 2017. SETTING: Greater Sydney, a metropolis of 4.5 million people in New South Wales, Australia. PARTICIPANTS: 34 women aged 70-74 with no personal history of breast cancer, recruited by random digit dialling and previously randomly recruited list-based samples...
June 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29903784/designing-prep-and-early-hiv-treatment-interventions-for-implementation-among-female-sex-workers-in-south-africa-developing-and-learning-from-a-formative-research-process
#14
Robyn Eakle, Nyaradzo Mutanha, Judie Mbogua, Maria Sibanyoni, Adam Bourne, Gabriela Gomez, Francois Venter, Helen Rees
OBJECTIVES: The objective of this research was to design relevant, tailored oral pre-exposure prophylaxis (PrEP) and early antiretroviral (ART) interventions for female sex workers (FSWs) in South Africa. This paper examines the methods, process and outcomes of employing an inductive approach to formative research exploring intervention feasibility and acceptability. SETTING: Research was conducted in several sex work-related settings including five sites in and around clinics and stakeholder offices...
June 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29903709/ashp-national-survey-of-pharmacy-practice-in-hospital-settings-dispensing-and-administration-2017
#15
Philip J Schneider, Craig A Pedersen, Douglas J Scheckelhoff
PURPOSE: The results of the 2017 ASHP national survey of pharmacy practice in hospital settings are described. METHODS: Pharmacy directors at 4,828 general and children's medical- surgical hospitals in the United States were surveyed using a mixed-mode method of contact by mail and e-mail. Survey completion was online, using Qualtrics (Qualtrics, Provo, UT). IMS Health supplied data on hospital characteristics; the survey sample was drawn from the IMS hospital database (IMS Health, Yardley, PA)...
June 14, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29903000/assessing-out-of-pocket-expenditures-for-primary-health-care-how-responsive-is-the-democratic-republic-of-congo-health-system-to-providing-financial-risk-protection
#16
Samia Laokri, Rieza Soelaeman, David R Hotchkiss
BACKGROUND: The goal of universal health coverage is challenging for chronically under-resourced health systems. Although household out-of-pocket payments are the most important source of health financing in low-income countries, relatively little is known about the drivers of primary health care expenditure and the predictability of the burden associated with high fee-for-service payments. This study describes out-of-pocket health expenditure and investigates demand- and supply-side drivers of excessive costs in the Democratic Republic of Congo (DRC), a central African country in the midst of a process of reforming its health financing system towards universal health coverage...
June 15, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29902996/three-years-in-changing-plan-features-in-the-u-s-health-insurance-marketplace
#17
Caitlin N McKillop, Teresa M Waters, Cameron M Kaplan, Erin K Kaplan, Michael P Thompson, Ilana Graetz
BACKGROUND: A central objective of recent U.S. healthcare policy reform, most notably the Affordable Care Act's (ACA) Health Insurance Marketplace, has been to increase access to stable, affordable health insurance. However, changing market dynamics (rising premiums, changes in issuer participation and plan availability) raise significant concerns about the marketplaces' ability to provide a stable source of healthcare for Americans that rely on them. By looking at the effect of instability on changes in the consumer choice set, we can analyze potential incentives to switch plans among price-sensitive enrollees, which can then be used to inform policy going forward...
June 15, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29901512/survival-associations-using-perfusion-and-diffusion-magnetic-resonance-imaging-in-patients-with-histologic-and-genetic-defined-diffuse-glioma-world-health-organization-grades-ii-and-iii
#18
Anna Latysheva, Kyrre Eeg Emblem, Andrés Server, Petter Brandal, Torstein R Meling, Jens Pahnke, John K Hald
OBJECTIVE: According to the new World Health Organization 2016 classification for tumors of the central nervous system, 1p/19q codeletion defines the genetic hallmark that differentiates oligodendrogliomas from diffuse astrocytomas. The aim of our study was to evaluate whether relative cerebral blood volume (rCBV) and apparent diffusion coefficient (ADC) histogram analysis can stratify survival in adult patients with genetic defined diffuse glioma grades II and III. METHODS: Sixty-seven patients with untreated diffuse gliomas World Health Organization grades II and III and known 1p/19q codeletion status were included retrospectively and analyzed using ADC and rCBV maps based on whole-tumor volume histograms...
June 12, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29901315/should-nurses-be-trained-to-use-ultrasound-for-intravenous-access-to-patients-with-difficult-veins
#19
Claire Smith
Peripheral venous access is the most common invasive procedure performed on patients in the UK and is traditionally the responsibility of nursing staff. In an emergency, intravenous therapy can be lifesaving. Approximately 11% of adults have difficult venous access and are often subjected to repeated failed attempts, resulting in delayed diagnosis and treatment. Eventually, rescue methods are used by a doctor, but this increases demand on their time and the workflow of emergency departments. This article explores whether training nurses to obtain venous access using ultrasound would have a positive effect on doctors' workload and benefit adult patients with difficult veins...
June 14, 2018: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/29900767/anesthesia-of-aquarium-housed-walrus-odobenus-rosmarus-a-case-series
#20
Johanna Kaartinen, Stéphane Lair, Michael T Walsh, Patrick Burns, Marion Desmarchelier, Jessica M Pang, Daniel S J Pang
  Walruses are a challenging species to anesthetize as a result of their large mass, limited access for drug delivery, unique physiology, and small number of reports describing anesthetic procedures. Three aquarium-housed walruses ( Odobenus rosmarus) ranging in age from 3 to 11 yr old (344-1,000 kg) were anesthetized for dental or ophthalmic surgical procedures, with one animal anesthetized twice and one anesthetized three times. Preanesthetic medication was with intramuscular midazolam (0.1-0.2 mg/kg) and meperidine (2-3 mg/kg)...
June 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
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