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stress treadmill testing

Christoph Schulze, Michael Becker, Susanne Finze, Christoph Holtherm, Jens Hinder, Andreas Lison
Occupational health promotion is an effective tool to improve the state of health of employees. As part of occupational health promotion in the German Bundeswehr, top-ranking military executives are offered a medical examination and training programme. Health-related data is collected as a basis for training and lifestyle counselling. This data was subjected to a retrospective evaluation in order to identify occupational risk factors and their correlation with cardiovascular resilience, trunk strength, and the development of orthopaedic and internal disorders...
2016: TheScientificWorldJournal
Ali Eshraghi, Reyhaneh Takalloo Ebdali, Seyed Sajed Sajjadi, Reza Golnezhad
INTRODUCTION: It is believed that an exaggerated blood pressure response (EBPR) to exercise stress test is associated with a higher risk of cardiovascular events. It is also assumed that QT dispersion (QT-d), which was originally proposed to measure the spatial dispersion of ventricular recovery times, may have a relationship to cardiovascular events. The objective of this study was to examine the difference of changes in QT-d, Maxi-QT, Mini-QT, and QT-c (corrected QT interval) of the electrocardiogram in two groups of patients with exaggerated blood pressure responses (EBPR group) and normal responses (control group) to exercise testing...
August 2016: Electronic Physician
Yusuf Ziya Tan, Semra Özdemir, Burak Altun, Fatmanur Çelik
OBJECTIVE: This study aimed to investigate the effects of assessment with myocardial perfusion scintigraphy (MPS) and heart rate recovery (HRrec) measurements in combination to evaluate the current status of patients with a diagnosis or suspicion of coronary artery disease (CAD). METHODS: A total of 350 patients were included in the study. CAD group consisted of 200 patients with stable angina pectoris and a known history of CAD, while the control group consisted of 150 patients with suspicious stress test who had no history of known CAD...
October 5, 2016: Molecular Imaging and Radionuclide Therapy
Daniel Jose Matos Medeiros-Lima, Antonio Claudio Mendes-Ribeiro, Tatiana Marlowe Cunha Brunini, Marcela Anjos Martins, Wanda Vianna Mury, Raul Almeira Freire, Walace David Monteiro, Paulo Tarso Veras Farinatti, Cristiane Matsuura
Growing evidence has shown that acute exercise impairs erythrocyte membrane structure and function as a consequence of increased physical and chemical stress. Erythrocyte-synthesized nitric oxide (NO) is known to modulate membrane fluidity, and its bioavailability depends on the balance between its production and scavenging by reactive oxygen species. Here, we investigated whether a maximal exercise test could affect erythrocyte NO bioavailability and oxidative stress. Twelve men (26±4 years old, V̇O2peak 44...
October 3, 2016: Clinical Hemorheology and Microcirculation
Nathan A Lewis, Colin Towey, Georgie Bruinvels, Glyn Howatson, Charles R Pedlar
Exercise causes alterations in redox homeostasis (ARH). Measuring ARH in elite athletes may aid in the identification of training tolerance, fatigued states, and underperformance. To the best of our knowledge, no studies have examined ARH in elite male and female distance runners at sea level. The monitoring of ARH in athletes is hindered by a lack of reliable and repeatable in-the-field testing tools and by the rapid turnaround of results. We examined the effects of various exercise intensities on ARH in healthy (non-over-reached) elite male and female endurance athletes using clinical point-of-care (POC) redox tests, referred to as the free oxygen radical test (FORT) (pro-oxidant) and the free oxygen radical defence (FORD) (antioxidant)...
October 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Yong Ki Lee, Bo Ryun Kim, Eun Young Han
OBJECTIVE: The aim of this work was to investigate the cardiorespiratory responses of patients with subacute stroke to exercise stress tests with aquatic and land treadmills. DESIGN: Twenty-one consecutive patients who presented with first-ever subacute stroke in 2013-2015. All subjects underwent symptom-limited incremental exercise testing with aquatic and land treadmills. Land treadmill speed started at 1.5 km/h and increased 0.5 km/h every 1 to 2 minutes until maximal tolerable speed was achieved...
August 19, 2016: American Journal of Physical Medicine & Rehabilitation
Subha V Raman, Jennifer A Dickerson, Wojciech Mazur, Timothy C Wong, Erik B Schelbert, James K Min, Debbie Scandling, Cheryl Bartone, Jason T Craft, Paaladinesh Thavendiranathan, Ernest L Mazzaferri, John W Arnold, Robert Gilkeson, Orlando P Simonetti
BACKGROUND: Stress cardiac magnetic resonance (CMR) has typically involved pharmacologic agents. Treadmill CMR has shown utility in single-center studies but has not undergone multicenter evaluation. METHODS AND RESULTS: Patients referred for treadmill stress nuclear imaging (SPECT) were prospectively enrolled across 4 centers. After rest (99m)Tc SPECT, patients underwent resting cine CMR. In-room stress was then performed using an MR-compatible treadmill with continuous 12-lead electrocardiogram monitoring...
2016: Journal of the American Heart Association
Joel Wilken
Palpitations are a symptom of many cardiac and noncardiac conditions. The patient's history, physical examination, appropriately directed laboratory tests, and basic electrocardiogram are helpful in evaluating palpitations and may be essential to finding a diagnosis. There are many outpatient options for the evaluation of palpitations caused by a presumed cardiogenic cause. These evaluation tools include Holter monitor, event monitor, transtelephonic electrocardiographic monitor, treadmill exercise stress test, echocardiography, and electrophysiologic studies...
September 2016: Medical Clinics of North America
Andrew J Murray, Nicholas S Knight, Mark A Cole, Lowri E Cochlin, Emma Carter, Kirill Tchabanenko, Tica Pichulik, Melanie K Gulston, Helen J Atherton, Marie A Schroeder, Robert M J Deacon, Yoshihiro Kashiwaya, M Todd King, Robert Pawlosky, J Nicholas P Rawlins, Damian J Tyler, Julian L Griffin, Jeremy Robertson, Richard L Veech, Kieran Clarke
Ketone bodies are the most energy-efficient fuel and yield more ATP per mole of substrate than pyruvate and increase the free energy released from ATP hydrolysis. Elevation of circulating ketones via high-fat, low-carbohydrate diets has been used for the treatment of drug-refractory epilepsy and for neurodegenerative diseases, such as Parkinson's disease. Ketones may also be beneficial for muscle and brain in times of stress, such as endurance exercise. The challenge has been to raise circulating ketone levels by using a palatable diet without altering lipid levels...
August 15, 2016: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Barbara M L C Bocco, João Pedro Werneck-de-Castro, Kelen C Oliveira, Gustavo W Fernandes, Tatiana L Fonseca, Bruna P P Nascimento, Elizabeth A McAninch, Esther Ricci, Zsuzsanna Kvárta-Papp, Csaba Fekete, Maria Martha Bernardi, Balázs Gereben, Antonio C Bianco, Miriam O Ribeiro
Millions of levothyroxine-treated hypothyroid patients complain of impaired cognition despite normal TSH serum levels. This could reflect abnormalities in the type 2 deiodinase (D2)-mediated T4-to-T3 conversion, given their much greater dependence on the D2 pathway for T3 production. T3 normally reaches the brain directly from the circulation or is produced locally by D2 in astrocytes. Here we report that mice with astrocyte-specific Dio2 inactivation (Astro-D2KO) have normal serum T3 but exhibit anxiety-depression-like behavior as found in open field and elevated plus maze studies and when tested for depression using the tail-suspension and the forced-swimming tests...
September 2016: Endocrinology
Habibollah Dehghan, Somayeh Gharehbaei, Behzad Mahaki
BACKGROUND: Heat stress is a threat to those who work in high temperatures. The purpose in this study was an examination of the cooling ability of Iranian phase change material (PCM) cold vest in hot and dry conditions in a climatic chamber. MATERIALS AND METHODS: This experimental study was implemented on 12 male students (age 23.7 ± 2.8 years, weight 66.1 ± 11.4 kg, and VO2 max 2.53 L/min) in 2013. The heat strain score index (HSSI), skin temperature and oral temperature, and heartbeat in two phases with and without cooling vest was measured during 30 min in a climatic chamber (temperature 38...
2016: Journal of Education and Health Promotion
Soleiman Mahjoub, Arezoo Ghadi, Roghayeh Pourbagher, Karimollah Hajian-Tilaki, Jila Masrour-Roudsari
BACKGROUND AND PURPOSE: Regular exercise can result in changes in the levels of oxidative stress in the hippocampus; however, little attention has been paid to physical-activity-induced neuronal protection to exposure to lead compounds. This study investigated the effects of regular treadmill exercise on a DNA oxidative-damage marker [8-hydroxy-2'-deoxyguanosine (8-OHdG)] and the total antioxidant capacity (TAC) of hippocampal tissue in lead-acetate exposed rats. METHODS: This study investigated the effects of 8 weeks of regular treadmill exercise on 8-OHdG and the TAC of hippocampal tissue in lead-acetate-exposed rats...
July 26, 2016: Journal of Clinical Neurology
Senay Akin, Hisashi Naito, Yuji Ogura, Noriko Ichinoseki-Sekine, Mitsutoshi Kurosaka, Ryo Kakigi, Haydar A Demirel
Heat shock proteins (Hsps) have a critical role in maintaining cellular homeostasis and in protecting cells from a range of acute and chronic stressful conditions. Treadmill running exercise results in increased Hsp72 and Hsp25 levels in various tissues and heat production during exercise has been shown to be the main factor for the increased levels of Hsp72 in myocardium. Since the adrenal gland plays a vital role in general response to stress, regulation of Hsps in adrenal glands following stressful events seems to be critical for controlling the whole-body stress response appropriately...
July 28, 2016: Journal of Physiological Sciences: JPS
James McKinney, Ian Pitcher, Christopher B Fordyce, Masoud Yousefi, Tee Joo Yeo, Andrew Ignaszewski, Saul Isserow, Sammy Chan, Krishnan Ramanathan, Carolyn M Taylor
BACKGROUND: Exercise-induced ST-segment elevation (STE) in lead aVR may be an important indicator of prognostically important coronary artery disease (CAD). However, the prevalence and associated clinical features of exercise-induced STE in lead aVR among consecutive patients referred for exercise stress electrocardiography (ExECG) is unknown. METHODS: All consecutive patients receiving a Bruce protocol ExECG for the diagnosis of CAD at a tertiary care academic center were included over a two-year period...
2016: PloS One
Wanda Acampa, Roberta Assante, Emilia Zampella
Treadmill exercise electrocardiogram (ECG) is one of the most commonly used noninvasive tests for the assessment of ischemic heart disease (IHD). Sex-specific challenges in diagnostic and prognostic tests methods for IHD outlined the importance of pretest probability evaluation and referral bias using risk-prediction charts available for both asymptomatic and symptomatic women. Accordingly, exercise ECG has been indicated as the initial test for the symptomatic women at intermediate risk of IHD who has a normal resting ECG and is capable of maximal exercise...
October 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Ghorban Taghizadeh, Jalal Pourahmad, Hajar Mehdizadeh, Alireza Foroumadi, Anahita Torkaman-Boutorabi, Shokoufeh Hassani, Parvaneh Naserzadeh, Reyhaneh Shariatmadari, Mahdi Gholami, Mohammad Reza Rouini, Mohammad Sharifzadeh
Debate continues about the effect of 3, 4-methylenedioxymethamphetamine (MDMA) on cognitive and mitochondrial function through the CNS. It has been shown that physical exercise has an important protective effect on cellular damage and death. Therefore, we investigated the effect of physical exercise on MDMA-induced impairments of spatial learning and memory as well as MDMA effects on brain mitochondrial function in rats. Male wistar rats underwent short-term (2 weeks) or long-term (4 weeks) treadmill exercise...
July 21, 2016: Free Radical Biology & Medicine
Marios Kolios, Panagiotis Korantzopoulos, Antonios P Vlahos, Eleni Kapsali, Evangelos Briasoulis, John A Goudevenos
BACKGROUND: There seems to be a significant arrhythmia burden in β-thalassemia major (TM) patients without overt cardiomyopathy. Apart from conventional electrocardiographic (ECG) and arrhythmic risk markers we studied novel markers of ventricular repolarization and autonomic imbalance both at rest and after exercise testing. METHODS: We studied 47 adult TM patients without systolic heart failure and 47 age and sex-matched healthy control subjects. The median age of the studied population was 36 [32-43] years, 57% men...
October 15, 2016: International Journal of Cardiology
Hee-Yun Kim, Na-Ra Han, Na-Rae Kim, Mikyung Lee, Jongbae Kim, Chang-Ju Kim, Hyun-Ja Jeong, Hyung-Min Kim
The fatigue spreads among the people who live under stressful life and brings about a negative impact on physical function. Here we evaluated the anti-fatigue effects of fermented porcine placenta (FPP) and main constituents, lysine (Lys) and leucine (Leu) with treadmill stress test and forced swimming test (FST) in animal models. The mice were administrated with FPP, Lys, and Leu for 21 days. After treadmill exercise, FPP, Lys, and Leu significantly reduced fatigue-related biochemical parameters, including lactate, lactate dehydrogenase, glucose, creatine kinase, urea nitrogen, cortisol, and pro-inflammatory cytokines, whereas superoxide dismutase activity and glycogen levels were significantly increased by FPP, Lys, and Leu...
November 2016: Experimental Biology and Medicine
Özgür Kasimay Çakir, Dilek Özbeyli, Ebru Şenel, Gazi Contuk, Ayliz Velioğlu Öğünç, Şule Çetinel, Berrak C Yeğen
BACKGROUND: There are contradictory results about stress response in hypothyroidism and in exercising ones with variant intensities. We aimed to investigate the potential anxiolytic and protective effects of different intensities of exercise on acute psychological stress in hypothyroidism. METHODS: Rats (n= 48) were divided as sedentary, moderate intensity (MIE) and high intensity exercise (HIE) groups. Rats were administered intraperitoneally with 6-n-propyl-2- thiouracil (PTU, 10 mg/kg) for 15 days to induce hypothyroidism...
July 13, 2016: Journal of Sports Medicine and Physical Fitness
June A Ejlersen, Steen H Poulsen, Jesper Mortensen, Ole May
BACKGROUND: Preinvasive risk stratification is recommended in patients suspected of coronary artery disease (CAD). Stress echocardiography (SE), myocardial perfusion scintigraphy (MPS), and exercise test are the dominant methods of choice. Vasodilator SE is fast and induces only minor increase in heart rate. The diagnostic value of the absolute stress-rest difference in endocardial global longitudinal strain (ΔeGLS) and wall motion (ΔWMI) from adenosine SE was compared to summed stress score (SSS) from MPS and Duke treadmill score (DTS) from exercise test, using quantitative invasive coronary angiography (ICA) as the reference...
July 11, 2016: Echocardiography
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