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Post-traumatic stress

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https://www.readbyqxmd.com/read/29341884/acute-stress-persistently-alters-locus-coeruleus-function-and-anxiety-like-behavior-in-adolescent-rats
#1
Olga Borodovitsyna, Matthew D Flamini, Daniel J Chandler
Stress is a physiological state characterized by altered neuroendocrine signaling, behavioral arousal, and anxiety. Chronic or traumatic stress may predispose individuals for multiple somatic and psychiatric illnesses. The locus coeruleus (LC) is a major node in the stress response that integrates input from multiple stress responsive neural circuits and releases norepinephrine throughout the central nervous system to promote vigilance and anxiety. Many mood disorders associated with prior stress are characterized by chronically altered noradrenergic signaling, yet the long-term impact of an acute stressor on LC function is not clear...
January 13, 2018: Neuroscience
https://www.readbyqxmd.com/read/29340154/the-impact-of-sepsis-delirium-and-psychological-distress-on-self-rated-cognitive-function-in-icu-survivors-a-prospective-cohort-study
#2
Emily Brück, Anna Schandl, Matteo Bottai, Peter Sackey
Background: Many intensive care unit (ICU) survivors develop psychological problems and cognitive impairment. The relation between sepsis, delirium, and later cognitive problems is not fully elucidated, and the impact of psychological symptoms on cognitive function is poorly studied in ICU survivors. The primary aim of this study was to examine the relationship between sepsis, ICU delirium, and later self-rated cognitive function. A second aim was to investigate the association between psychological problems and self-rated cognitive function 3 months after the ICU stay...
2018: Journal of Intensive Care
https://www.readbyqxmd.com/read/29337007/postnatal-post-traumatic-stress-an-integrative-review
#3
Madeleine Simpson, Virginia Schmied, Cathy Dickson, Hannah Grace Dahlen
PROBLEM: Post-traumatic stress disorder and post-traumatic stress symptoms following birth occur amongst a small proportion of women but can lead to poor maternal mental health, impairment in mother-infant bonding and relationship stress. This integrative review aims to examine the associated risk factors and women's own experiences of postnatal post-traumatic stress in order to better understand this phenomenon. METHOD: Fifty three articles were included and critically reviewed using the relevant Critical Appraisal Skills Program checklists or Strengthening the Reporting of Observational studies in Epidemiology assessment tool...
January 11, 2018: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29335846/cotinine-a-therapy-for-memory-extinction-in-post-traumatic-stress-disorder
#4
REVIEW
Cristhian Mendoza, George E Barreto, Alexandre Iarkov, Vadim V Tarasov, Gjumrakch Aliev, Valentina Echeverria
Post-traumatic stress disorder (PTSD) is a mental disorder that may develop after exposure to exceptionally threatening or unescapable horrifying events. Actual therapies fail to alleviate the emotional suffering and cognitive impairment associated with this disorder, mostly because they are ineffective in treating the failure to extinguish trauma memories in a great percentage of those affected. In this review, current behavioral, cellular, and molecular evidence supporting the use of cotinine for treating PTSD are reviewed...
January 15, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29334643/longitudinal-determinants-of-depression-among-world-trade-center-health-registry-enrollees-14-15-years-after-the-9-11-attacks
#5
Melanie H Jacobson, Christina Norman, Angela Nguyen, Robert M Brackbill
BACKGROUND: Exposure to the September 11, 2001 (9/11) terrorist attacks has been found to be associated with posttraumatic stress disorder (PTSD) and comorbid PTSD and depression up to 10-11 years post-disaster. However, little is known about the longitudinal predictors of mental health conditions over time. METHODS: We examined longitudinal determinants of depression within strata of PTSD among 21,258 enrollees of the World Trade Center Health Registry who completed four questionnaires over 14 years of follow-up (Wave 1 in 2003-04; Wave 2 in 2005-06; Wave 3 in 2011-12; and Wave 4 in 2015-16)...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29334231/social-capital-and-ptsd-among-plwha-in-china-the-mediating-role-of-resilience-and-internalized-stigma
#6
Mengting Gao, Chenchang Xiao, Xuan Zhang, Shiyue Li, Hong Yan
Post-traumatic Stress Disorder (PTSD) is frequent among people living with HIV/AIDS (PLWHA). Few studies have investigated social-psychological predictors of PTSD in China. This study aimed to examine relationships between social capital, stigma, resilience and PTSD among PLWHA in China, and to provide effective suggestions for PTSD intervention. A cross-sectional study of 520 PLWHA was conducted from November 2015 to January 2016. Survey data were collected using anonymous self-reported questionnaire. Multivariable analyses were used to examine related factors of PTSD, and causal mediation analyses were conducted to assess whether stigma and resilience were mediators...
January 15, 2018: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/29332015/post-traumatic-stress-and-growth-among-cpr-survivors-in-the-southeast-of-iran
#7
Seyed Hamid Seyed Bagheri, Sedigheh Iranmanesh, Masoud Rayyani, Mahlagha Dehghan, Batool Tirgari, Seyed Habibollah Hosseini
Background Almost 7.2%-10.6% of patients survive CPR in Iran. Most of them experience post-traumatic stress disorder (PTSD) and post-traumatic growth (PTG). There are limited studies to assessing the correlation between these two psychological outcomes among CPR survivors. Objective This study aimed to examine the correlation between PTSD and PTG among CPR survivors in South-East Iran. Subjects Using Quota sampling, 163 CPR survivors in two provinces in the South-East of Iran were selected to participate in this study...
January 13, 2018: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/29331930/sleep-quality-psychological-symptoms-and-psychotic-like-experiences
#8
Arielle Ered, Shanna Cooper, Lauren M Ellman
Poor sleep quality has been repeatedly linked to the entire psychosis continuum, including psychotic-like experiences (PLEs); however, sleep dysfunction is a component of several other psychopathologies that have also been linked to increased risk for PLEs, including depression, anxiety, and post-traumatic stress disorder (PTSD). It has yet to be examined if PLEs are a significant risk factor for poor sleep quality or if this sleep dysfunction is better accounted for by comorbid psychopathology. In 2687 undergraduates, PLEs were evaluated using the positive items of the Prodromal Questionnaire...
December 26, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29331707/the-mediation-effect-of-ptsd-perceived-job-stress-and-resilience-on-the-relationship-between-trauma-exposure-and-the-development-of-depression-and-alcohol-use-problems-in-korean-firefighters-a-cross-sectional-study
#9
Johanna Inhyang Kim, Heyeon Park, Jeong-Hyun Kim
BACKGROUND: Firefighters constitute a high-risk group for depression and alcohol use disorders (AUDs) due to frequent exposure to trauma. Perceived job stress and resilience are powerful factors affecting the occurrence of depression and AUDs; however, research on this subject is scarce. METHODS: We investigated the relationship of perceived job stress and resilience with depression or AUDs in firefighters. A total of 7151 Korean firefighters were included for analysis...
December 29, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29331697/longitudinal-trajectories-of-post-traumatic-stress-disorder-ptsd-after-birth-and-associated-risk-factors
#10
Pelin Dikmen-Yildiz, Susan Ayers, Louise Phillips
BACKGROUND: Although longitudinal trajectories of post-traumatic stress disorder (PTSD) are well-established in general trauma populations, very little is known about the trajectories of birth-related PTSD. This study aimed to identify trajectories of birth-related PTSD; determine factors associated with each trajectory; and identify women more likely to develop birth-related PTSD. METHOD: 226 women who had traumatic childbirth according to DSM-IV criterion A were drawn from a community sample of 950 women...
January 2, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29330769/comorbid-insomnia-and-sleep-apnea-in-veterans-with-post-traumatic-stress-disorder
#11
Ali A El-Solh, David Adamo, Thomas Kufel
PURPOSE: The purpose of this study was to determine the impact of insomnia in Veterans with post-traumatic stress disorder (PTSD) and obstructive sleep apnea (OSA) on health-related outcomes before and after 12 weeks of continuous positive airway pressure (CPAP) treatment. METHODS: We conducted a prospective cohort study of Veterans with PTSD and documented apnea hypopnea index (AHI) ≥ 5 with and without clinically significant insomnia as determined by the Insomnia Severity Index (ISI)...
January 10, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29330217/a-systematic-review-of-network-meta-analyses-for-pharmacological-treatment-of-common-mental-disorders
#12
REVIEW
Taryn Williams, Dan J Stein, Jonathan Ipser
QUESTION: Network meta-analyses (NMAs) of treatment efficacy across different pharmacological treatments help inform clinical decision-making, but their methodological quality may vary a lot depending also on the quality of the included primary studies. We therefore conducted a systematic review of NMAs of pharmacological treatment for common mental disorders in order to assess the methodological quality of these NMAs, and to relate study characteristics to the rankings of efficacy and tolerability...
January 12, 2018: Evidence-based Mental Health
https://www.readbyqxmd.com/read/29330035/harmine-enhances-gabaergic-transmission-onto-basoamygdala-projection-neurons-in-mice
#13
Wei-Zhu Liu, Bo-Wei Huang, Wen-Jie You, Ping Hu, Xue-Hui Wang, Jun-Yu Zhang, Xiao-Bin Xu, Zong-Yong Zhang, Bing-Xing Pan, Wen-Hua Zhang
Emerging evidence indicates that loss of inhibitory tone in amygdala with its subsequent overactivation contributes to the development of multiple mental disorders such as anxiety disorders and post-traumatic stress disorder (PTSD). Harmine is a member of natural β-carboline alkaloids which can readily cross the blood brain barrier and displays significant antidepressant and anxiolytic effects in rodents. However, the underlying neurobiological mechanisms are largely unknown. Here, by using whole-cell patch clamp recordings in in vitro amygdala slices, we examined the effect of harmine on glutamatergic and GABAergic transmission onto basal amygdala (BA) projection neurons (PNs)...
January 9, 2018: Brain Research Bulletin
https://www.readbyqxmd.com/read/29329065/factors-associated-with-depression-among-homeless-mothers-results-of-the-enfams-survey
#14
M Roze, S Vandentorren, J Van-Der-Waerden, M Melchior
PURPOSE: Women are disproportionately likely to suffer from depression. This is especially true for those who experience socioeconomic hardship, such as homelessness. In France, among homeless mothers many are migrant. However, it is not clear whether risk factors associated with depression are specific for this group or the same as in the general population. Our objective was to describe socio-demographic, relational, living and housing conditions and health factors associated with depression among homeless mothers...
January 6, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29328883/a-systematic-review-of-interleukin-1%C3%AE-in-post-traumatic-stress-disorder-evidence-from-human-and-animal-studies
#15
Aysha Waheed, Bethan Dalton, Ulrich Wesemann, Mohammad A A Ibrahim, Hubertus Himmerich
Pro-inflammatory cytokines, such as interleukin (IL)-1β, have been implicated as underlying pathophysiological mechanisms and potential biomarkers of post-traumatic stress disorder (PTSD). This systematic review examines data regarding IL-1β production/concentration in human and animal studies of PTSD. In accordance with PRISMA guidelines, relevant articles from PubMed were reviewed from inception until July 10, 2017. Nineteen studies were eligible for inclusion. Animal studies demonstrated increased hippocampal IL-1β in rodent models of PTSD...
January 2018: Journal of Interferon & Cytokine Research
https://www.readbyqxmd.com/read/29328681/seizures-among-active-component-service-members-u-s-armed-forces-2007-2016
#16
Julie A Bytnar, Shauna Stahlman, Saixia Ying
Traumatic brain injury (TBI) is a known risk factor for seizures. Evidence also shows that post-traumatic stress disorder (PTSD) is associated with seizures, but the relationship in the absence of TBI remains unclear. This retrospective study spanning 2007-2016 separately quantifies the rates of seizures diagnosed among deployed and non-deployed active component military service members to understand the factors associated with seizures and whether they differ in deployed settings. Higher rates of seizures were associated with service members who were in the Army or Marine Corps; female; black; younger; lower enlisted; in a combat-specific, armor/motor transport, or healthcare occupation; and who had no more than one previous deployment...
December 2017: MSMR
https://www.readbyqxmd.com/read/29327856/post-traumatic-stress-disorder
#17
Michael C Mithoefer, Lisa Jerome, Candice Monson
No abstract text is available yet for this article.
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29327855/post-traumatic-stress-disorder
#18
Michal Turcek
No abstract text is available yet for this article.
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29327854/post-traumatic-stress-disorder
#19
Eric L Altschuler
No abstract text is available yet for this article.
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29327258/mental-health-problems-of-syrian-refugee-children-the-role-of-parental-factors
#20
Seyda Eruyar, John Maltby, Panos Vostanis
War-torn children are particularly vulnerable through direct trauma exposure as well through their parents' responses. This study thus investigated the association between trauma exposure and children's mental health, and the contribution of parent-related factors in this association. A cross-sectional study with 263 Syrian refugee children-parent dyads was conducted in Turkey. The Stressful Life Events Questionnaire (SLE), General Health Questionnaire, Parenting Stress Inventory (PSI-SF), Impact of Events Scale for Children (CRIES-8), and Strengths and Difficulties Questionnaire were used to measure trauma exposure, parental psychopathology, parenting-related stress, children's post-traumatic stress symptoms (PTSS), and mental health problems, respectively...
January 11, 2018: European Child & Adolescent Psychiatry
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