keyword
MENU ▼
Read by QxMD icon Read
search

PHI

keyword
https://www.readbyqxmd.com/read/28523507/tof-sims-parallel-imaging-ms-ms-of-lipid-species-in-thin-tissue-sections
#1
Anne Lisa Bruinen, Gregory L Fisher, Ron M A Heeren
Unambiguous identification of detected species is essential in complex biomedical samples. To date, there are not many mass spectrometry imaging techniques that can provide both high spatial resolution and identification capabilities. A new and patented imaging tandem mass spectrometer, exploiting the unique characteristics of the nanoTOF II (Physical Electronics, USA) TOF-SIMS TRIFT instrument, was developed to address this.Tandem mass spectrometry is based on the selection of precursor ions from the full secondary ion spectrum (MS(1)), followed by energetic activation and fragmentation, and collection of the fragment ions to obtain a tandem MS spectrum (MS(2))...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28523213/brachial-plexus-magnetic-resonance-imaging-differentiates-between-inflammatory-neuropathies-and-does-not-predict-disease-course
#2
Bas A Jongbloed, Jeroen W Bos, Dirk Rutgers, Willem Ludo van der Pol, Leonard H van den Berg
OBJECTIVE: The main objective of this study was to evaluate the correlation between the distribution of brachial plexus magnetic resonance imaging (MRI) abnormalities and clinical weakness, and to evaluate the value of brachial plexus MRI in predicting disease course and response to treatment in multifocal motor neuropathy (MMN), Lewis-Sumner syndrome (LSS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). METHODS: Sixty-seven patients with an inflammatory neuropathy diagnosed at our tertiary referral center for neuromuscular diseases had undergone bilateral T2-weighted short tau inversion recovery (STIR) MRI of the brachial plexus...
May 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28499764/-personal-health-records-on-the-internet-a-narrative-review-of-attitudes-expectations-utilization-and-effects-on-health-outcomes
#3
REVIEW
Dominik Ose, Ines Baudendistel, Sabrina Pohlmann, Eva C Winkler, Aline Kunz, Joachim Szecsenyi
BACKGROUND: The integration of information and communication technologies (ICT) is increasingly considered in the development of healthcare structures. This fact is also recognised in the e-Health Act. In this context, personal health records (PHR) have a specific meaning. The aim of this paper is to provide an overview on utilization, barriers and possible effects on the implementation of PHR. METHODS: This analysis is based on a literature search in Web of Science (Core Collection) (01/2000 to 12/2014) using the following terms: "personal health record", "personal medical record", "personal electronic health record", "interpersonal health record", "personally controlled health record"...
May 9, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28498816/the-prostate-health-index-phi-predicts-oncological-outcome-and-biochemical-recurrence-after-radical-prostatectomy-analysis-in-437-patients
#4
Andreas Maxeiner, Ergin Kilic, Julia Matalon, Frank Friedersdorff, Kurt Miller, Klaus Jung, Carsten Stephan, Jonas Busch
The purpose of this study was to investigate the Prostate-Health-Index (PHI) for pathological outcome prediction following radical prostatectomy and also for biochemical recurrence prediction in comparison to established parameters such as Gleason-score, pathological tumor stage, resection status (R0/1) and prostate-specific antigen (PSA).Out of a cohort of 460 cases with preoperative PHI-measurements (World Health Organization calibration: Beckman Coulter Access-2-Immunoassay) between 2001 and 2014, 437 patients with complete follow up data were included...
April 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28497781/face-classification-using-electronic-synapses
#5
Peng Yao, Huaqiang Wu, Bin Gao, Sukru Burc Eryilmaz, Xueyao Huang, Wenqiang Zhang, Qingtian Zhang, Ning Deng, Luping Shi, H-S Philip Wong, He Qian
Conventional hardware platforms consume huge amount of energy for cognitive learning due to the data movement between the processor and the off-chip memory. Brain-inspired device technologies using analogue weight storage allow to complete cognitive tasks more efficiently. Here we present an analogue non-volatile resistive memory (an electronic synapse) with foundry friendly materials. The device shows bidirectional continuous weight modulation behaviour. Grey-scale face classification is experimentally demonstrated using an integrated 1024-cell array with parallel online training...
May 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/28495760/anco3-a-new-member-of-the-emerging-family-of-phage-like-plasmids
#6
Anna Colavecchio, Julie Jeukens, Luca Freschi, Jean-Guillaume Edmond Rheault, Irena Kukavica-Ibrulj, Roger Levesque, Lawrence Goodridge
A phage-like plasmid isolated from a clinical isolate of Salmonella enterica serovar Derby has strong nucleotide sequence identity to the phage-like plasmids pSTM_phi isolated from Salmonella enterica serovar Typhimurium L495, AnCo1 and AnCo2 from Escherichia coli 243 and Escherichia coli 244, and the virulent Salmonella-specific SSU5 bacteriophage.
May 11, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28490576/complement-c5a-functions-as-a-master-switch-for-the-ph-balance-in-neutrophils-exerting-fundamental-immunometabolic-effects
#7
Stephanie Denk, Miriam D Neher, David A C Messerer, Rebecca Wiegner, Bo Nilsson, Daniel Rittirsch, Kristina Nilsson-Ekdahl, Sebastian Weckbach, Anita Ignatius, Miriam Kalbitz, Florian Gebhard, Manfred E Weiss, Josef Vogt, Peter Radermacher, Jörg Köhl, John D Lambris, Markus S Huber-Lang
During sepsis, excessive activation of the complement system with generation of the anaphylatoxin C5a results in profound disturbances in crucial neutrophil functions. Moreover, because neutrophil activity is highly dependent on intracellular pH (pHi), we propose a direct mechanistic link between complement activation and neutrophil pHi In this article, we demonstrate that in vitro exposure of human neutrophils to C5a significantly increased pHi by selective activation of the sodium/hydrogen exchanger. Upstream signaling of C5a-mediated intracellular alkalinization was dependent on C5aR1, intracellular calcium, protein kinase C, and calmodulin, and downstream signaling regulated the release of antibacterial myeloperoxidase and lactoferrin...
May 10, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28490158/endoscopic-endonasal-approach-for-suprasellar-lesions-in-children-complications-and-prevention
#8
REVIEW
Yong Hwy Kim, Kyu-Chang Wang, Ji Hoon Phi, Seung-Ki Kim
The endoscopic endonasal approach (EEA) has been popularized in adults and has been applied to an expanding range of surgical modules and indications in this population. However, its clinical application in pediatric neurosurgery has been impeded by the differences in anatomical features and the relatively low incidence of diseases to which it is applicable. In this review article, we mainly discuss the surgical indications, feasibility, and complications of EEA for suprasellar lesions in children based on a review of the literature, focusing especially on the age-related anatomical features of the nasal cavity, various pathologic entities, and the impact of EEA on long-term craniofacial growth...
May 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28490153/prevention-of-complications-in-endoscopic-third-ventriculostomy
#9
REVIEW
Tae-Young Jung, Sangjoon Chong, In-Young Kim, Ji Yeoun Lee, Ji Hoon Phi, Seung-Ki Kim, Jae-Hyoo Kim, Kyu-Chang Wang
A variety of complications in endoscopic third ventriculostomy have been reported, including neurovascular injury, hemodynamic alterations, endocrinologic abnormalities, electrolyte imbalances, cerebrospinal fluid leakage, fever and infection. Even though most complications are transient, the overall rate of permanent morbidity is 2.38% and the overall mortality rate is 0.28%. To avoid these serious complications, we should keep in mind potential complications and how to prevent them. Proper decisions with regard to surgical indication, choice of endoscopic entry and trajectory, careful endoscopic procedures with anatomic orientation, bleeding control and tight closure are emphasized for the prevention of complications...
May 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28486182/dissipation-occurrence-and-risk-assessment-of-a-phenylurea-herbicide-tebuthiuron-in-sugarcane-and-aquatic-ecosystems-in-south-china
#10
Yuan Qian, Haruna Matsumoto, Xiaoyu Liu, Shuying Li, Xiao Liang, Yanan Liu, Guonian Zhu, Mengcen Wang
In this study, a modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method coupled with UPLC-QqQ-MS/MS analysis was developed to detect tebuthiuron in sugarcane fields and the surrounding aquatic ecosystems. Methodological validation showed the method developed was of favorable sensitivity, reproducibility and accuracy. For assessment of its dietary and ecological risks, dissipation and occurrence of tebuthiuron in situ were further investigated through a supervised field trial and an aquatic environment monitoring carried out in six dominant sugarcane production regions in South China...
May 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28485610/synthesis-of-the-staphylococcus-aureus-strain-m-capsular-polysaccharide-repeating-unit
#11
Bas Hagen, J Hessel M van Dijk, Qingju Zhang, Herman S Overkleeft, Gijsbert A van der Marel, Jeroen D C Codée
The synthesis of the Staphylococcus aureus strain M capsular polysaccharide repeating unit is reported. A postglycosylation oxidation strategy was utilized for the construction of the α-galactosaminuronic acid linkages, relying on a stereoselective 2-azido-4,6-O-di-tert-butylsilylidene galactopyranoside donor, for which the selectivity was assessed by model glycosylations. The α-fucosamine linkage was installed stereoselectively, using a reactive 2-azidofucosyl donor. An unexpected glycosidic bond cleavage during the TEMPO/PhI(OAc)2-mediated oxidation of a disaccharide intermediate was circumvented by a TEMPO/PhI(OAc)2-Pinnick oxidation protocol...
May 9, 2017: Organic Letters
https://www.readbyqxmd.com/read/28484706/endophytic-actinobacteria-associated-with-dracaena-cochinchinensis-lour-isolation-diversity-and-their-cytotoxic-activities
#12
Nimaichand Salam, Thi-Nhan Khieu, Min-Jiao Liu, Thu-Trang Vu, Son Chu-Ky, Ngoc-Tung Quach, Quyet-Tien Phi, Manik Prabhu Narsing Rao, Angélique Fontana, Samira Sarter, Wen-Jun Li
Dracaena cochinchinensis Lour. is an ethnomedicinally important plant used in traditional Chinese medicine known as dragon's blood. Excessive utilization of the plant for extraction of dragon's blood had resulted in the destruction of the important niche. During a study to provide a sustainable way of utilizing the resources, the endophytic Actinobacteria associated with the plant were explored for potential utilization of their medicinal properties. Three hundred and four endophytic Actinobacteria belonging to the genera Streptomyces, Nocardiopsis, Brevibacterium, Microbacterium, Tsukamurella, Arthrobacter, Brachybacterium, Nocardia, Rhodococcus, Kocuria, Nocardioides, and Pseudonocardia were isolated from different tissues of D...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28484514/increased-lignocellulosic-inhibitor-tolerance-of-saccharomyces-cerevisiae-cell-populations-in-early-stationary-phase
#13
Venkatachalam Narayanan, Jenny Schelin, Marie Gorwa-Grauslund, Ed Wj van Niel, Magnus Carlquist
BACKGROUND: Production of second-generation bioethanol and other bulk chemicals by yeast fermentation requires cells that tolerate inhibitory lignocellulosic compounds at low pH. Saccharomyces cerevisiae displays high plasticity with regard to inhibitor tolerance, and adaptation of cell populations to process conditions is essential for reaching efficient and robust fermentations. RESULTS: In this study, we assessed responses of isogenic yeast cell populations in different physiological states to combinations of acetic acid, vanillin and furfural at low pH...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28482123/integrative-analysis-of-transcriptomic-and-metabolomic-data-via-sparse-canonical-correlation-analysis-with-incorporation-of-biological-information
#14
Sandra E Safo, Shuzhao Li, Qi Long
Integrative analysis of high dimensional omics data is becoming increasingly popular. At the same time, incorporating known functional relationships among variables in analysis of omics data has been shown to help elucidate underlying mechanisms for complex diseases. In this article, our goal is to assess association between transcriptomic and metabolomic data from a Predictive Health Institute (PHI) study that includes healthy adults at a high risk of developing cardiovascular diseases. Adopting a strategy that is both data-driven and knowledge-based, we develop statistical methods for sparse canonical correlation analysis (CCA) with incorporation of known biological information...
May 8, 2017: Biometrics
https://www.readbyqxmd.com/read/28481771/cd4-cd8-ratio-restoration-in-long-term-treated-hiv-1-infected-individuals-incidence-and-determinants
#15
Fabienne Caby
OBJECTIVES: A persistently low CD4/CD8 ratio despite virological control reflects a higher risk of morbidity in HIV-infected individuals. The objective of the study was to assess the probability and determinants of ratio restoration (≥1) during long-term cART. DESIGN: Study cohort based on the French Hospital Database on HIV (FHDH-ANRS CO4). METHODS: Antiretroviral naïve HIV-1 infected individuals were included if they achieved virological control (plasma HIV-RNA≤500 copies/ml) within 9 months following cART, started between 2000 and 2010...
May 5, 2017: AIDS
https://www.readbyqxmd.com/read/28480160/public-use-of-electronic-personal-health-information-measuring-progress-of-the-healthy-people-2020-objectives
#16
Alexandra J Greenberg, Katrina J Serrano, Chan L Thai, Kelly D Blake, Richard P Moser, Bradford W Hesse, David K Ahern
Use of the internet for seeking and managing health information in the U.S., Europe, and emerging and developing nations is growing. Recent global trends indicate more interactive uses of the internet including online communication with providers. In the U.S., The Healthy People 2020 (HP2020) initiative was created by the Department of Health and Human Services to provide 10-year goals for improving the health of American citizens. Two goals of HP2020 were to increase the proportion of individuals who use the Internet to keep track of their personal health information (PHI) online and to increase the proportion of individuals who use the internet to communicate with their healthcare provider...
March 2017: Health Policy and Technology
https://www.readbyqxmd.com/read/28477291/the-effect-of-complementary-private-health-insurance-on-the-use-of-health-care-services
#17
Astrid Kiil, Jacob Nielsen Arendt
This study estimates the effect of complementary private health insurance (PHI) on the use of health care. The empirical analysis focuses on an institutional setting in which empirical findings are still limited; namely on PHI covering co-payment for treatments that are only partly financed by a universal health care system. The analysis is based on Danish data recently collected specifically for this purpose, which makes identification strategies assuming selection on observables only, and on both observables and unobservables also, both plausible and possible...
March 2017: International Journal of Health Economics and Management
https://www.readbyqxmd.com/read/28472323/hiv-1-strains-belonging-to-large-phylogenetic-clusters-show-accelerated-escape-from-integrase-inhibitors-in-cell-culture-compared-with-viral-isolates-from-singleton-small-clusters
#18
Bluma G Brenner, Ruxandra-Ilinca Ibanescu, Maureen Oliveira, Michel Roger, Isabelle Hardy, Jean-Pierre Routy, Fred Kyeyune, Miguel E Quiñones-Mateu, Mark A Wainberg
Objectives: Viral phylogenetics revealed two patterns of HIV-1 spread among MSM in Quebec. While most HIV-1 strains ( n  =   2011) were associated with singleton/small clusters (cluster size 1-4), 30 viral lineages formed large networks (cluster size 20-140), contributing to 42% of diagnoses between 2011 and 2015. Herein, tissue culture selections ascertained if large cluster lineages possessed higher replicative fitness than singleton/small cluster isolates, allowing for viral escape from integrase inhibitors...
May 2, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28468859/isolation-of-campylobacter-species-from-stool-samples-using-a-filtration-method-assessment-from-a-u-s-based-population
#19
Irving Nachamkin, Phi Nguyen
Fecal samples submitted to our clinical microbiology laboratory from patients in the Philadelphia region were prospectively analyzed for Campylobacter species other than C. jejuni and C. coli using a filtration method and microaerobic conditions with increased H2 concentrations. Of 225 samples tested, 13 (5.8%) yielded Campylobacter species with frequent isolation of C. concisus. The majority of Campylobacter species were not clinically significant. Additional studies in U.S. populations are warranted.
May 3, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28467979/negative-effect-of-ellagic-acid-on-cytosolic-ph-regulation-and-glycolytic-flux-in-human-endometrial-cancer-cells
#20
Khalid N M Abdelazeem, Yogesh Singh, Florian Lang, Madhuri S Salker
BACKGROUND/AIMS: Key properties of tumor cells include enhanced glycolytic flux with excessive consumption of glucose and formation of lactate. As glycolysis is highly sensitive to cytosolic pH, maintenance of glycolysis requires export of H+ ions, which is in part accomplished by Na+/H+ exchangers, such as NHE1. The carrier is sensitive to oxidative stress. Growth of tumor cells could be suppressed by the polyphenol Ellagic acid, which is found in various fruits and vegetables. An effect of Ellagic acid on transport processes has, however, never been reported...
April 27, 2017: Cellular Physiology and Biochemistry
keyword
keyword
84484
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"