keyword
MENU ▼
Read by QxMD icon Read
search

Transperineal biopsy

keyword
https://www.readbyqxmd.com/read/29108322/the-predictive-efficacy-of-hypoechoic-lesion-in-ultrasound-for-prostate-cancer-in-chinese-people-five-year-experience-in-a-moderated-10-core-transperineal-prostate-biopsy-procedure
#1
Tian Yang, Limin Zhang, Yixin Chen, Yehua Cai, Haowen Jiang, Qiang Ding
We aim to investigate the predictive efficacy of hypoechoic lesion for prostate cancer at different levels of serum PSA in the procedure of transrectal ultrasound guided 10-core trans-perineal prostate biopsy (TP-PBx). In this study, we collected clinical parameters involving age, digital rectal examination (DRE), PSA, prostate volume, pathological diagnosis, Gleason score, novel Gleason group, and numbers of positive cores from 856 patients who had elevated level of PSA above 4 ng/ml or susceptible nodule of prostate gland in DRE received the moderated 10-core TP-PBx procedure...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29107269/how-to-biopsy-transperineal-versus-transrectal-saturation-versus-targeted-what-s-the-evidence
#2
REVIEW
Jeremy Grummet
Until recently, prostate biopsy for the detection of prostate cancer has been performed transrectally and in an untargeted sampling fashion. Consequently, the procedure has suffered a small but significant risk of severe morbidity through infection, and low diagnostic accuracy, with undergrading and missed diagnosis being common. MRI is revolutionizing prostate cancer diagnosis by improving detection accuracy via targeted biopsy. Transperineal biopsy is eradicating sepsis as a risk of prostate biopsy, while avoiding the need for broad-spectrum or combination prophylactic antibiotics...
November 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/29102671/preliminary-diagnostic-accuracy-of-multiparametric-magnetic-resonance-imaging-to-detect-residual-prostate-cancer-following-focal-therapy-with-irreversible-electroporation
#3
Matthijs J Scheltema, John I Chang, Willemien van den Bos, Maret Böhm, Warick Delprado, Ilan Gielchinsky, Theo M de Reijke, Jean J de la Rosette, Amila R Siriwardana, Ron Shnier, Phillip D Stricker
BACKGROUND: It is recommended to perform multiparametric magnetic resonance imaging (mpMRI) in the follow-up following focal therapy of prostate cancer (PCa). OBJECTIVE: To determine the diagnostic accuracy of mpMRI to detect residual PCa following focal therapy with irreversible electroporation. DESIGN, SETTING, AND PARTICIPANTS: Seventy-six patients with biopsy-proven localized PCa consented for primary irreversible electroporation between February 2013 and March 2016...
November 1, 2017: European Urology Focus
https://www.readbyqxmd.com/read/29102647/the-transcriptional-landscape-of-radiation-treated-human-prostate-cancer-analysis-of-a-prospective-tissue-cohort
#4
Simon P Keam, Franco Caramia, Cristina Gamell, Piotr J Paul, Gisela Mir Arnau, Paul J Neeson, Scott G Williams, Ygal Haupt
PURPOSE: The resistance of prostate cancer to radiation therapy (RT) is a significant clinical issue and still largely unable to be guided by patient-specific molecular characteristics. The present study describes the gene expression changes induced in response to RT in human prostate tissue obtained from a prospective tissue acquisition study designed for radiobiology research. METHODS AND MATERIALS: A prospective cohort of 5 men with intermediate-risk and clinically localized tumors were treated with high-dose-rate brachytherapy with 2 × 10-Gy fractions...
September 25, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29094042/evaluation-of-mri-ultrasound-fusion-guided-prostate-biopsy-using-transrectal-and-transperineal-approaches
#5
Susanne Tewes, Inga Peters, Ansgar Tiemeyer, Matti Peperhove, Dagmar Hartung, Stefanie Pertschy, Markus A Kuczyk, Frank Wacker, Katja Hueper
Purpose: To evaluate transrectal (TR) and transperineal (TP) approaches for MRI/ultrasound (MRI/US) fusion-guided biopsy to detect prostate cancer (PCa). Materials and Methods: 154 men underwent multiparametric MRI and MRI/US fusion-guided biopsy between July 2012 and October 2016. 79/154 patients were biopsied with a TR approach and 75/154 with a TP approach. MRI was retrospectively analyzed according to PI-RADS version 2. PI-RADS scores were compared with histopathological results...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29034221/atypical-small-acinar-proliferation-and-two-or-more-cores-of-high-grade-intraepithelial-neoplasia-on-a-previous-prostate-biopsy-are-significant-predictors-of-cancer-during-a-transperineal-template-guided-saturation-biopsy-aimed-at-sampling-one-core-for-each
#6
Yasushi Nakai, Nobumichi Tanaka, Makito Miyake, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Tomomi Fujii, Noboru Konishi, Kiyohide Fujimoto
OBJECTIVE: The objective of this study was to evaluate whether high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical small acinar proliferation (ASAP) predict prostate cancer (PCa) during repeat transperineal template saturation biopsy with a high number of cores per prostate volume in patients with persistent clinical suspicion of PCa who underwent at least one previous negative transrectal ultrasound (TRUS)-guided biopsy. METHODS: We retrospectively evaluated 135 consecutive patients with persistent clinical suspicion of PCa, despite a set of negative TRUS-guided biopsies and increasing prostate-specific antigen levels; abnormal findings on digital rectal examination, TRUS, or magnetic resonance imaging; previous biopsy showing HGPIN; and previous biopsy showing atypical glands...
2017: Research and Reports in Urology
https://www.readbyqxmd.com/read/29024425/multicentre-evaluation-of-magnetic-resonance-imaging-supported-transperineal-prostate-biopsy-in-biopsy-na%C3%A3-ve-men-with-suspicion-of-prostate-cancer
#7
N L Hansen, T Barrett, C Kesch, L Pepdjonovic, D Bonekamp, R O'Sullivan, F Distler, A Warren, C Samel, B Hadaschik, J Grummet, C Kastner
OBJECTIVES: To analyse the detection rates of primary MRI-fusion transperineal prostate biopsy using combined targeted and systematic core distribution in three tertiary referral centres. PATIENTS AND METHODS: Multicentre, prospective outcome study of 807 consecutive biopsy-naïve patients having undergone MRI-guided transperineal prostate biopsy as the first diagnostic intervention between 10/2012 and 05/2016. MRI was reported following PI-RADS criteria. 236 patients had 18-24 systematic transperineal biopsies only, and 571 patients underwent additional targeted biopsies either by MRI-fusion or cognitive targeting if PI-RADS ≥3 lesions were present...
October 11, 2017: BJU International
https://www.readbyqxmd.com/read/28987685/sub-differentiating-equivocal-pi-rads-3-lesions-in-multiparametric-magnetic-resonance-imaging-of-the-prostate-to-improve-cancer-detection
#8
N L Hansen, B C Koo, A Y Warren, C Kastner, T Barrett
PURPOSE: To evaluate sub-differentiation of PI-RADS-3 prostate lesions using pre-defined T2- and diffusion-weighted (DWI) MRI criteria, to aid the biopsy decision process. METHODS: 143 patients with PIRADS-3 index lesions on MRI underwent targeted transperineal-MR/US fusion biopsy. Radiologists with 2 and 7-years experience performed blinded retrospective second-reads using set criteria and assigned biopsy recommendations. Inter-reader agreement, Gleason score (GS), positive (PPV) predictive values (±95% confidence intervals) were calculated and compared by Fisher's exact test with Bonferroni-Hom correction...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28969413/the-eternal-enigma-in-prostatic-biopsy-access-route
#9
Andrea Fabiani, Emanuele Principi, Alessandra Filosa, Lucilla Servi
Dear Editors,We read with interest the article by Di Franco and co-workers (1). The introduction of prostatic magnetic resonance and the relative fusion-biopsy have not yet allowed the expected improvements in prostate biopsy. To our knowledge, there are no works that demonstrate the superiority of fusion techniques on the remaining ultrasound guided prostate biopsies that are still the widely used in the diagnosis of prostate cancer. Furthemore, these technologies are expensive exams and they are not yet available in all centers, especially in those minors...
October 3, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28961847/intratumoural-evolutionary-landscape-of-high-risk-prostate-cancer-the-progeny-study-of-genomic-and-immune-parameters
#10
M Linch, G Goh, C Hiley, Y Shanmugabavan, N McGranahan, A Rowan, Y N S Wong, H King, A Furness, A Freeman, J Linares, A Akarca, J Herrero, R Rosenthal, N Harder, G Schmidt, G A Wilson, N J Birkbak, R Mitter, S Dentro, P Cathcart, M Arya, E Johnston, R Scott, M Hung, M Emberton, G Attard, Z Szallasi, S Punwani, S A Quezada, T Marafioti, M Gerlinger, H U Ahmed, C Swanton
Background: Intratumoural heterogeneity (ITH) is well recognised in prostate cancer (PC), but its role in high-risk disease is uncertain. A prospective, single-arm, translational study using targeted multiregion prostate biopsies was carried out to study genomic and T-cell ITH in clinically high-risk PC aiming to identify drivers and potential therapeutic strategies. Patients and methods: Forty-nine men with elevated prostate-specific antigen and multiparametric-magnetic resonance imaging detected PC underwent image-guided multiregion transperineal biopsy...
October 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28941761/direct-comparison-of-pi-rads-version-2-and-version-1-regarding-interreader-agreement-and-diagnostic-accuracy-for-the-detection-of-clinically-significant-prostate-cancer
#11
Anton S Becker, Alexander Cornelius, Cäcilia S Reiner, Daniel Stocker, Erika J Ulbrich, Borna K Barth, Ashkan Mortezavi, Daniel Eberli, Olivio F Donati
PURPOSE: to simultaneously evaluate interreader agreement and diagnostic accuracy in the of PI-RADS v2 and compare it to v1. METHODS: A total of 67 patients (median age 65.3 y, range 51.2-78.2 y; PSA 6.8μg/L, 0.2-33μg/L) undergoing MRI of the prostate and subsequent transperineal template biopsy within ≤6 months from MRI were included. Four readers from two institutions evaluated the likelihood of prostate cancer using PI-RADS v1 and v2 in two separate reading sessions ≥3 months apart...
September 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28924476/clinical-validation-of-real-time-tissue-change-monitoring-during-prostate-tissue-ablation-with-high-intensity-focused-ultrasound
#12
Narendra T Sanghvi, Wo-Hsing Chen, Roy Carlson, Clint Weis, Ralf Seip, Toyoaki Uchida, Michael Marberger
BACKGROUND: The purpose of these clinical studies was to validate a Tissue Change Monitoring (TCM) algorithm in vivo. TCM is a quantitative tool for the real-time assessment of HIFU dose. TCM provides quantitative analysis of the backscatter pulse echo signals (pre and immediately post HIFU) for each individual ablative site, using ultrasonic tissue characterization as a surrogate for monitoring tissue temperature. Real-time analysis generates an energy difference parameter (ΔE in dB) that is proportional to tissue temperature...
2017: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/28921850/prospective-comparison-of-transperineal-mri-ultrasound-fusion-biopsy-and-transrectal-systematic-biopsy-in-biopsy-na%C3%A3-ve-patients
#13
Angelika Borkowetz, Boris Hadaschik, Ivan Platzek, Marieta Toma, Georgi Torsev, Theresa Renner, Roman Herout, Martin Baunacke, Michael Laniado, Gustavo Baretton, Jan Philipp Radtke, Claudia Kesch, Markus Hohenfellner, Michael Froehner, Heinz-Peter Schlemmer, Manfred Wirth, Stefan Zastrow
OBJECTIVES: To evaluate the value of multiparametric magnetic resonance imaging (mpMRI) for the detection of significant prostate cancer (PCa) and to compare transperineal MRI/ultrasound-fusion biopsy (fusPbx) to conventional transrectal systematic biopsy (sysPbx) in biopsy-naïve patients. PATIENTS AND METHODS: This multicentre, prospective trial investigated biopsy-naïve patients with suspicion of PCa undergoing transperineal fusPbx in combination with transrectal sysPbx (comPbx)...
September 16, 2017: BJU International
https://www.readbyqxmd.com/read/28867930/mr-safe-robot-fda-clearance-safety-and-feasibility-prostate-biopsy-clinical-trial
#14
Dan Stoianovici, Chunwoo Kim, Doru Petrisor, Changhan Jun, Sunghwan Lim, Mark W Ball, Ashley Ross, Katarzyna J Macura, Mohamad Allaf
Compatibility of mechatronic devices with the MR environment has been a very challenging engineering task. After over a decade of developments, we report the successful translation to clinical trials of our MR Safe robot technology. MrBot is a 6-degree-of-freedom, pneumatically actuated robot for transperineal prostate percutaneous access, built exclusively of electrically nonconductive and nonmagnetic materials. Its extensive pre-clinical tests have been previously reported. Here, we present the latest technology developments, an overview of the regulatory protocols, and technically related results of the clinical trial...
February 2017: IEEE/ASME Transactions on Mechatronics
https://www.readbyqxmd.com/read/28836176/elevated-hardness-of-peripheral-gland-on-real-time-elastography-is-an-independent-marker-for-high-risk-prostate-cancers
#15
Qi Zhang, Jing Yao, Yehua Cai, Limin Zhang, Yishuo Wu, Jingyu Xiong, Jun Shi, Yuanyuan Wang, Yi Wang
OBJECTIVES: To examine the role of quantitative real-time elastography (RTE) features on differentiation between high-risk prostate cancer (PCA) and non-high-risk prostatic diseases in the initial transperineal biopsy setting. METHODS: We retrospectively included 103 patients with suspicious PCA who underwent both RTE and initial transperineal prostate biopsy. Patients were grouped into high-risk and non-high-risk categories according to the D'Amico's risk stratification...
August 23, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28801025/toward-an-mri-based-nomogram-for-the-prediction-of-transperineal-prostate-biopsy-outcome-a-physician-and-patient-decision-tool
#16
Su-Min Lee, Sidath H Liyanage, Wahyu Wulaningsih, Konrad Wolfe, Thomas Carr, Choudhry Younis, Mieke Van Hemelrijck, Rick Popert, Peter Acher
PURPOSE: To develop and internally validate a nomogram using biparametric magnetic resonance imaging (B-MRI)-derived variables for the prediction of prostate cancer at transperineal sector-guided prostate biopsy (TPSB). SUBJECTS/PATIENTS AND METHODS: Consecutive patients referred to our institution with raised prostate-specific antigen (PSA), abnormal prostate examination, or persistent suspicion of prostate cancer after previous transrectal biopsy between July 2012 and November 2015 were reviewed from a prospective database...
November 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28783264/high-cancer-detection-rate-using-cognitive-fusion-targeted-transperineal-prostate-biopsies
#17
Snir Dekalo, Haim Matzkin, Nicola J Mabjeesh
OBJECTIVE: MRI of the prostate improves diagnostic accuracy of prostate cancer. Different fusion approaches with transrectal ultrasound images are employed. To determine detection rate of prostate cancer in men undergoing transperineal MRIbased cognitive fusion biopsy. MATERIALS AND METHODS: One hundred and sixty-four consecutive men underwent a multiple-core prostate transperineal biopsy. Univariable and multivariable logistic regression analyses were used to address the relationship between clinical parameters and prostate cancer detection rate...
July 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28771912/comparison-of-lesions-detected-and-undetected-by-template-guided-transperineal-saturation-prostate-biopsy
#18
Zhipeng Mai, Yu Xiao, Weigang Yan, Yi Zhou, Zhien Zhou, Zhiyong Liang, Zhigang Ji, Hanzhong Li
OBJECTIVES: To compare the characteristics of lesions detected or undetected by template-guided transperineal saturation prostate biopsy and to evaluate the potential impact of undetected lesions. MATERIALS AND METHODS: We evaluated the characteristics of lesions in radical prostatectomy (RP) specimens, compared the differences between lesions detected and undetected by systematic transperineal ultrasonography-guided 11-region biopsy with regard to tumour volume, Gleason score, surgical margin, spatial location and clinical significance, and assessed the potential impact of undetected clinically significant lesions...
August 3, 2017: BJU International
https://www.readbyqxmd.com/read/28768264/pathological-concordance-between-prostate-biopsies-and-radical-prostatectomy-using-transperineal-sector-mapping-biopsies-validation-and-comparison-with-transrectal-biopsies
#19
Giancarlo Marra, David Eldred-Evans, Ben Challacombe, Mieke Van Hemelrijck, Alexander Polson, Sabine Pomplun, Christopher S Foster, Christian Brown, Declan Cahill, Paolo Gontero, Rick Popert, Gordon Muir
Background/Aims/Objectives: Our aim was to evaluate the accuracy of systematic transperineal sector mapping biopsy (TPSMB) in predicting Gleason score (GS) at radical prostatectomy (RP), to compare its accuracy with standard transrectal ultrasound-guided biopsies (TRUS) and to establish the clinical impact of discordance between biopsies and RP on subsequent surgical management. METHODS: Two hundred fifty-five patients from 2008 to 2013 who underwent RP following TPSMB (n = 204) or TRUS (n = 51), were included in this retrospective multi-institutional study...
2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28749035/comparison-between-target-magnetic-resonance-imaging-mri-in-gantry-and-cognitively-directed-transperineal-or-transrectal-guided-prostate-biopsies-for-prostate-imaging-reporting-and-data-system-pi-rads-3-5-mri-lesions
#20
COMPARATIVE STUDY
Anna J Yaxley, John W Yaxley, Isaac A Thangasamy, Emma Ballard, Morgan R Pokorny
OBJECTIVE: To compare the detection rates of prostate cancer (PCa) in men with Prostate Imaging-Reporting and Data System (PI-RADS) 3-5 abnormalities on 3-Tesla multiparametric (mp) magnetic resonance imaging (MRI) using in-bore MRI-guided biopsy compared with cognitively directed transperineal (cTP) biopsy and transrectal ultrasonography (cTRUS) biopsy. METHODS: This was a retrospective single-centre study of consecutive men attending the private practice clinic of an experienced urologist performing MRI-guided biopsy and an experienced urologist performing cTP and cTRUS biopsy techniques for PI-RADS 3-5 lesions identified on 3-Tesla mpMRI...
November 2017: BJU International
keyword
keyword
84483
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"