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Transperineal biopsy

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https://www.readbyqxmd.com/read/28222486/accuracy-of-real-time-magnetic-resonance-imaging-transrectal-ultrasound-fusion-image-guided-transperineal-target-biopsy-with-needle-tracking-with-a-mechanical-position-encoded-stepper-in-detecting-significant-prostate-cancer-in-biopsy-na%C3%A3-ve-men
#1
Sunao Shoji, Shinichiro Hiraiwa, Takahiro Ogawa, Masayoshi Kawakami, Mayura Nakano, Kazunobu Hashida, Yoshinobu Sato, Terumitsu Hasebe, Toyoaki Uchida, Takuma Tajiri
OBJECTIVE: To evaluate the accuracy of real-time elastic fusion image-guided transperineal prostate biopsy with needle tracking involving a mechanical position-encoded stepper in detecting clinically significant prostate cancer for biopsy-naïve men. METHODS: We prospectively recruited patients with serum prostate-specific antigen levels of 4.0-20 ng/mL and suspicious of prostate cancer on multiparametric magnetic resonance imaging. They underwent targeted biopsies for cancer-suspicious lesions and 12-core systematic biopsies...
February 21, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28192761/a-comparison-of-bayesian-and-non-linear-regression-methods-for-robust-estimation-of-pharmacokinetics-in-dce-mri-and-how-it-affects-cancer-diagnosis
#2
Nikolaos Dikaios, David Atkinson, Chiara Tudisca, Pierpaolo Purpura, Martin Forster, Hashim Ahmed, Timothy Beale, Mark Emberton, Shonit Punwani
The aim of this work is to compare Bayesian Inference for nonlinear models with commonly used traditional non-linear regression (NR) algorithms for estimating tracer kinetics in Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI). The algorithms are compared in terms of accuracy, and reproducibility under different initialization settings. Further it is investigated how a more robust estimation of tracer kinetics affects cancer diagnosis. The derived tracer kinetics from the Bayesian algorithm were validated against traditional NR algorithms (i...
February 5, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/28186627/value-of-three-section-contrast-enhanced-transrectal-ultrasonography-in-the-detection-of-prostate-cancer
#3
Ting-Yue Qi, Hong-Guang Sun, Nian-Fen Li, Hao Feng, Yong-Ling Ding, Xiao-Xiang Wang
BACKGROUND: To assess the efficacy of three-section contrast-enhanced transrectal ultrasonography (CETRUS) in prostate cancer (PCa) detection. METHODS: A total of 169 consecutive patients with either PSA level ≥ 4 ng/ml or abnormal digital rectal examination findings were prospectively enrolled in this single center study. All patients underwent baseline transrectal ultrasonography (TRUS) and three-section CETRUS by one investigator blinded to any clinical data before TRUS-guided transperineal biopsy...
February 10, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28177897/comparison-between-transrectal-and-transperineal-prostate-biopsy-for-detection-of-prostate-cancer-a-meta-analysis-and-trial-sequential-analysis
#4
Jianxin Xue, Zhiqiang Qin, Hongzhou Cai, Chuanjie Zhang, Xiao Li, Weizhang Xu, Jingyuan Wang, Zicheng Xu, Bin Yu, Ting Xu, Qin Zou
To systematically assess the efficacy and complications of transrectal (TR) versus transperineal (TP) prostate biopsy in the detection of prostate cancer (PCa). A meta-analysis was performed by searching the databases Pubmed, Embase and Web of science for the relevant available studies until September 1st, 2016, and thirteen studies met the inclusion criteria. The pooled odds ratios with 95% confidence intervals were calculated to evaluate the differences of TR and TP groups in PCa detection rate. Then, trial sequential analysis was performed to reduce the risk of type I error and estimated whether the evidence of the results was reliable...
February 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/28154882/transperineal-gold-marker-implantation-for-image-guided-external-beam-radiotherapy-of-prostate-cancer-a-single-institution-prospective-study
#5
Kliton Jorgo, Péter Ágoston, Tibor Major, Zoltán Takácsi-Nagy, Csaba Polgár
PURPOSE: To present the feasibility and complications of transperineal fiducial marker implantation in prostate cancer patients undergoing image-guided radiotherapy (IGRT) METHODS AND MATERIALS: Between November 2011 and April 2016, three radiopaque, gold-plated markers were transperineally implanted into the prostate of 300 patients under transrectal ultrasound guidance and with local anaesthesia. A week after the procedure patients filled in a questionnaire regarding pain, dysuria, urinary frequency, nocturia, rectal bleeding, hematuria, hematospermia or fever symptoms caused by the implantation...
February 2, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28124523/predictive-role-of-trimprob-associated-with-multiparametric-mri-in-the-diagnosis-of-prostate-cancer
#6
Gustavo Cardoso Guimaraes, Walter Henriques da Costa, Renato Almeida Rosa, Stênio Zequi, Ricardo Favaretto
OBJECTIVES: To evaluate the predictive value of TRIMprob test to detect prostate cancer (PCa) in patients referred to prostate biopsy (PB). MATERIAL AND METHODS: Patients with PSA <10ng/mL and rectal exam without findings suggestive of prostate cancer were selected for TRIMprob evaluation. Exam was performed by a single operator through transperineal approach. Patients admitted for the study were submitted to TRIMprob and multiparametric magnetic resonance (mpMRI) and posteriorly to PB...
January 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28073197/detection-rate-for-significant-cancer-at-confirmatory-biopsy-in-men-enrolled-in-active-surveillance-protocol-20-cores-vs-30-cores-vs-mri-trus-fusion-prostate-biopsy
#7
Pietro Pepe, Sebastiano Cimino, Antonio Garufi, Giandomenico Priolo, Giorgio Ivan Russo, Raimondo Giardina, Giulio Reale, Michele Barbera, Paolo Panella, Michele Pennisi, Giuseppe Morgia
INTRODUCTION: The detection rate for significant prostate cancer of extended vs saturation vs mMRI/TRUS fusion biopsy was prospectively evaluated in men enrolled in active surveillance (AS) protocol. Mterials and methods: From May 2013 to September 2016 75 men aged 66 years (median) with very low risk PCa were enrolled in an AS protocol and elegible criteria were: life expectancy greater than 10 years, cT1C, PSA below 10 ng/ml, PSA density < 0.20, 2 < unilateral positive biopsy cores, Gleason score (GS) equal to 6, greatest percentage of cancer (GPC) in a core < 50%...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28009149/robotic-assisted-laparoscopic-radical-prostatectomy-following-transrectal-compared-to-transperineal-prostate-biopsy-surgical-oncological-and-functional-outcomes
#8
Karan Wadhwa, Giulio Patruno, Andrew Patterson, Tristan Barrett, Chandni Dalia, Brendan C Koo, Ferdia A Gallagher, Eva Serrao, Anne Warren, Vincent Gnanapragasam, Nimish Shah, Andrew Doble, Christof Kastner
BACKGROUND: To assess if transperineal prostate (TP) biopsy affects th e outcome of robotic-assisted laparoscopic prostatectomy (RALP), with particular reference to perioperative complications, oncological results and functional outcomes in the early postoperative setting. METHODS: We identified 61 men who had undergone RALP after TP biopsies, from June 2012 to June 2014 and a control group of 120 men who had undergone RALP after conventional TRUS biopsy in the same period...
February 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28007492/prostate-biopsy-related-infection-a-systematic-review-of-risk-factors-prevention-strategies-and-management-approaches
#9
REVIEW
Matthew J Roberts, Harrison Y Bennett, Patrick N Harris, Michael Holmes, Jeremy Grummet, Kurt Naber, Florian M E Wagenlehner
A systematic review to identify risk factors for prostate biopsy-related infection, preventative strategies and optimal management of infectious complications was conducted. Significant risk factors for post biopsy infection include urogenital infection, antibiotic use, international travel, hospital exposure, bacteriuria, previous transrectal biopsy and resistance of faecal flora to antibiotic prophylaxis (especially fluoroquinolones). Patients at risk may benefit from an adjusted biopsy protocol comprising transrectal biopsy under targeted prophylaxis, and/or the use of rectal disinfection techniques or using a transperineal approach...
December 19, 2016: Urology
https://www.readbyqxmd.com/read/28005230/comparison-of-free-hand-transperineal-mpmri-trus-fusion-guided-biopsy-with-transperineal-12-core-systematic-biopsy-for-the-diagnosis-of-prostate-cancer-a-single-center-prospective-study-in-china
#10
Qing Zhang, Wei Wang, Bing Zhang, Jong Shi, Yao Fu, Danyan Li, Suhan Guo, Shengjie Zhang, Haifeng Huang, Xuping Jiang, Weimin Zhou, Hongqian Guo
OBJECTIVES: To prospectively compare biopsy outcomes between free-hand transperineal mpMRI/TRUS fusion targeted biopsy (TB) and transperineal systematic biopsy (SB) in patients with first prostate biopsy. PATIENTS AND METHODS: In all, 224 consecutive patients with the suspicion of PCa were investigated. All patients were evaluated by 3.0-T mpMRI applying the ESUR criteria. All patients underwent free-hand transperineal mpMRI/TRUS fusion TB and additionally a transperineal SB...
December 22, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27995114/gleason-group-concordance-between-biopsy-and-radical-prostatectomy-specimens-a-cohort-study-from-prostate-cancer-outcome-registry-victoria
#11
Sue M Evans, Varuni Patabendi Bandarage, Caroline Kronborg, Arul Earnest, Jeremy Millar, David Clouston
BACKGROUND: A new prostate cancer (PCa) prognostic grading system [Gleason groups (GGs)] has been proposed based on the contemporary Gleason scores (GSs), which has five simplified prognostic categories. The objective of this study was to evaluate the agreement between the GGs of prostate biopsy and radical prostatectomy specimens and to identify predictive factors for upgrading GGs. METHODS: A total of 5339 cases of RP notified to the Prostate Cancer Outcomes Registry, Victoria, Australia over 6 years (2009-2014) from 46 hospitals, were included...
December 2016: Prostate International
https://www.readbyqxmd.com/read/27990424/diagnostic-accuracy-of-robot-guided-software-based-transperineal-mri-trus-fusion-biopsy-of-the-prostate-in-a-high-risk-population-of-previously-biopsy-negative-men
#12
Malte Kroenig, Kathrin Schaal, Matthias Benndorf, Martin Soschynski, Philipp Lenz, Tobias Krauss, Vanessa Drendel, Gian Kayser, Philipp Kurz, Martin Werner, Ulrich Wetterauer, Wolfgang Schultze-Seemann, Mathias Langer, Cordula A Jilg
Objective. In this study, we compared prostate cancer detection rates between MRI-TRUS fusion targeted and systematic biopsies using a robot-guided, software based transperineal approach. Methods and Patients. 52 patients received a MRIT/TRUS fusion followed by a systematic volume adapted biopsy using the same robot-guided transperineal approach. The primary outcome was the detection rate of clinically significant disease (Gleason grade ≥ 4). Secondary outcomes were detection rate of all cancers, sampling efficiency and utility, and serious adverse event rate...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27987032/zero-hospital-admissions-for-infection-after-577-transperineal-prostate-biopsies-using-single-dose-cephazolin-prophylaxis
#13
Lana Pepdjonovic, Guan Hee Tan, Sean Huang, Sarah Mann, Mark Frydenberg, Daniel Moon, Uri Hanegbi, Adam Landau, Ross Snow, Jeremy Grummet
PURPOSE: To determine the rate of hospital admissions for infection after transperineal biopsy of prostate (TPB) with single-dose cephazolin prophylaxis using a prospective database. METHOD: Between April 2013 and February 2016, 577 patients undergoing TPB had 2 g of cephazolin given intravenously at induction of anaesthesia. Data collected from these patients included age, PSA, prostate volume, number of cores taken and post-operative complications. RESULTS: No patients were readmitted to hospital with infection post-TPB...
December 16, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27955940/magnetic-resonance-imaging-transrectal-ultrasound-fusion-focal-cryotherapy-of-the-prostate-a-prospective-development-study
#14
Massimo Valerio, Taimur Tariq Shah, Paras Shah, Neil Mccartan, Mark Emberton, Manit Arya, Hashim Uddin Ahmed
OBJECTIVES: The use of software-based magnetic resonance-transrectal ultrasound fusion to deliver focal therapy may increase the precision of treatment. This is a prospective development study assessing the feasibility of Magnetic resonance imaging-transrectal ultrasound (MRI-TRUS) fusion focal cryotherapy. METHODS AND MATERIALS: Consecutive patients undergoing focal cryotherapy were included in an academic registry (December 2013-June 2014). MRI-TRUS fusion focal cryotherapy was offered to men with visible clinically significant prostate cancer (Galil SeedNet system)...
December 7, 2016: Urologic Oncology
https://www.readbyqxmd.com/read/27919653/transperineal-biopsies-of-mri-detected-aggressive-index-lesions-in-low-%C3%A2-and-intermediate-risk-prostate-cancer-patients-implications-for-treatment-decision
#15
A Gomez-Iturriaga, F Casquero, J I Lopez, A Urresola, A Ezquerro, D Buscher, P Bilbao, J Crook
PURPOSE: Multiparametric MRI (mpMRI) has a potential role for the identification of aggressive cancer that can be targeted for biopsy. We report the incidence and severity of discordant information between the pathology found on the transrectal ultrasound (TRUS)-guided biopsy and the mpMRI findings in patients with favorable or intermediate-risk prostate cancer referred for brachytherapy. METHODS AND MATERIALS: From March 2014 to September 2015, 10/44 consecutive patients with low- or intermediate-risk prostate cancer referred for brachytherapy presented an aggressive lesion on mpMRI and underwent an MRI-TRUS fusion-guided transperineal biopsy of the index lesion...
January 2017: Brachytherapy
https://www.readbyqxmd.com/read/27906722/location-and-grade-of-prostate-cancer-diagnosed-by-transperineal-template-guided-mapping-biopsy-after-negative-transrectal-ultrasound-guided-biopsy
#16
Nathan Bittner, Gregory Merrick, Al Taira, Abbey Bennett, Amy Schattel, Wayne Butler, Robert Galbreath, Edward Adamovich
OBJECTIVES: To determine the location and grade of prostate cancer diagnosed by transperineal template-guided mapping (TTMB) after negative transrectal ultrasound-guided (TRUS) biopsy. MATERIALS AND METHODS: This analysis consisted of 1118 consecutive patients who underwent TTMB from January 2005 to August 2015. Eight hundred thirty-five underwent TTMB after at least 1 negative TRUS biopsy and 283 underwent TTMB as the first biopsy procedure. The study population was divided into cohorts based on the number of prior TRUS biopsy sessions (0, 1, 2, and ≥3)...
November 30, 2016: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27900453/incidence-grade-and-distribution-of-prostate-cancer-following-transperineal-template-guided-mapping-biopsy-in-patients-with-atypical-small-acinar-proliferation
#17
Gregory S Merrick, Robert W Galbreath, Abbey Bennett, Wayne M Butler, Edward Amamovich
PURPOSE: To evaluate the role of transperineal template-guided mapping biopsy (TTMB) in patients with atypical small acinar proliferation (ASAP) diagnosed via transrectal ultrasound-guided needle biopsy (TRUS). METHODS: In total, 132 consecutive patients with TRUS-diagnosed ASAP underwent TTMB by means of an anatomic-based technique with sampling of 24 biopsy regions. For each of the 24 regions, 1-3 biopsy cores were obtained (depending on prostate size). No patient underwent pre-biopsy MRI imaging...
November 29, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27862869/multicentre-evaluation-of-targeted-and-systematic-biopsies-using-magnetic-resonance-and-ultrasound-image-fusion-guided-transperineal-prostate-biopsy-in-patients-with-a-previous-negative-biopsy
#18
Nienke L Hansen, Claudia Kesch, Tristan Barrett, Brendan Koo, Jan P Radtke, David Bonekamp, Heinz-Peter Schlemmer, Anne Y Warren, Kathrin Wieczorek, Markus Hohenfellner, Christof Kastner, Boris Hadaschik
OBJECTIVES: To evaluate the detection rates of targeted and systematic biopsies in magnetic resonance imaging (MRI) and ultrasound (US) image-fusion transperineal prostate biopsy for patients with previous benign transrectal biopsies in two high-volume centres. PATIENTS AND METHODS: A two centre prospective outcome study of 487 patients with previous benign biopsies that underwent transperineal MRI/US fusion-guided targeted and systematic saturation biopsy from 2012 to 2015...
November 10, 2016: BJU International
https://www.readbyqxmd.com/read/27859637/assessing-clinically-significant-prostate-cancer-diagnostic-properties-of-multiparametric-magnetic-resonance-imaging-compared-to-three-dimensional-transperineal-template-mapping-histopathology
#19
Matvey Tsivian, Rajan T Gupta, Efrat Tsivian, Peter Qi, Melissa H Mendez, Michael R Abern, Kae Jack Tay, Thomas J Polascik
OBJECTIVE: To evaluate the diagnostic properties of multiparametric magnetic resonance imaging in the detection, localization and characterization of prostate cancer using three-dimensional transperineal template mapping biopsy histopathology as the comparator. METHODS: A retrospective analysis of patients undergoing prostate multiparametric magnetic resonance imaging followed by three-dimensional transperineal template mapping biopsy was carried out. For imaging and pathology data, the prostate was divided in octants with the urethra being the midline...
November 8, 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/27856226/indications-utilization-and-complications-following-prostate-biopsy-a-new-york-state-analysis
#20
Joshua A Halpern, Art Sedrakyan, Brian Dinerman, Wei-Chun Hsu, Jialin Mao, Jim C Hu
PURPOSE: Uptake of active surveillance and changes in prostate cancer care may affect the utilization of and complications following prostate needle biopsy. We characterized recent trends and risk factors for prostate needle biopsy complications using a statewide, all-payer cohort. MATERIALS AND METHODS: We used SPARCS (New York Statewide Planning and Research Cooperation System) to identify prostate needle biopsies performed between 2011 and 2014 via the transrectal and the transperineal approach (9,472 and 421 patients, respectively)...
November 14, 2016: Journal of Urology
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