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https://www.readbyqxmd.com/read/28531337/correlation-of-immune-phenotype-with-idh-mutation-in-diffuse-glioma
#1
Anna Sophie Berghoff, Barbara Kiesel, Georg Widhalm, Dorothee Wilhelm, Orsolya Rajky, Sebastian Kurscheid, Philip Kresl, Adelheid Wöhrer, Christine Marosi, Monika E Hegi, Matthias Preusser
Background: Tumor infiltrating lymphocytes (TILs) and programmed death ligand 1 (PD-L1) are targets of immune checkpoint inhibitors. Methods: Forty-three World Health Organization (WHO) grade II/III gliomas (39 IDH-mutant [mut], 4 IDH-wildtype [wt]) and 14 IDH-mut glioblastomas (GBM) were analyzed for TIL (CD3+; PD1+) infiltration and PD-L1 expression. Results were compared with the data of a previously published series of 117 IDH-wt glioblastomas. PD-L1 gene expression levels were evaluated in 677 diffuse gliomas grades II-IV from The Cancer Genome Atlas (TCGA) database...
May 20, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28530433/efficacy-of-a-multilevel-intervention-on-the-mental-health-of-people-living-with-hiv-and-their-family-members-in-rural-china
#2
Li Li, Guoping Ji, Li-Jung Liang, Chunqing Lin, Julie Hsieh, Chiao-Wen Lan, Yongkang Xiao
OBJECTIVE: HIV has a profound impact on infected individuals and their families. This study evaluated the efficacy of an intervention aimed at improving the mental health of people living with HIV (PLH) and their family members. METHOD: A randomized controlled trial of 475 PLH and 522 family members was conducted in Anhui, China. The intervention comprised activities at individual, family, and community levels. The study outcomes, which included depressive symptoms and coping with illness for the PLH and depressive symptoms and caregiver burden for the family members, were assessed at baseline and at 6-, 12-, 18-, and 24-month follow-up...
May 22, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28529669/veggie-van-pilot-study-impact-of-a-mobile-produce-market-for-underserved-communities-on-fruit-and-vegetable-access-and-intake
#3
Lucia A Leone, Lindsey Haynes-Maslow, Alice S Ammerman
We conducted a pilot evaluation of the Veggie Van, a mobile produce market that brings weekly boxes of reduced-cost locally grown fruits and vegetables (F&V) to lower-income communities and offers cooking and nutrition education to customers. We conducted surveys just prior to starting Veggie Van at each of 3 sites and again at 2-3 months. F&V intake was measured with a 2-question item and a 10-item food frequency questionnaire (FFQ) in a subset of participants. At baseline, average servings/day of F&V was 4...
2017: Journal of Hunger & Environmental Nutrition
https://www.readbyqxmd.com/read/28529546/disease-management-programs-for-patients-with-type-2-diabetes-mellitus-in-germany-a-longitudinal-population-based-descriptive-study
#4
Michael Mehring, Ewan Donnachie, Florian Cornelius Bonke, Christoph Werner, Antonius Schneider
BACKGROUND: The primary aim of the disease management program (DMP) for patients with diabetes mellitus type 2 is to improve the quality of health care and the treatment process. 12 years after its introduction in Germany, there is still no consensus as to whether DMP has been effective in reaching these goals. METHODS: A retrospective longitudinal population-based study between 2004 and 2015 were conducted to evaluate the DMP for type 2 diabetes in Bavaria using routinely collected patient medical records hold from the National Association of Statutory Health Insurance Physicians of Bavaria...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28529088/pilot-test-of-a-home-based-program-to-prevent-perceived-insufficient-milk
#5
Natsuko K Wood, Elizabeth A Sanders, Frances M Lewis, Nancy F Woods, Susan T Blackburn
PROBLEM: Although the World Health Organization and American Academy of Pediatrics recommend exclusive breastfeeding for the first six months, only 22% of U.S. mothers do so. Mothers' perceived insufficient milk (PIM) is the primary reason for breastfeeding discontinuation globally. There are two changeable causes of PIM: (1) mothers' misinterpretation of their infant's behavior, and (2) mothers' lack of confidence in their ability to breastfeed. AIM: The purpose of this study was to evaluate the short-term effect of a home-based intervention designed to prevent and/or reduce PIM...
May 18, 2017: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/28528694/factors-influencing-the-transition-from-pediatric-to-adult-care-a-scoping-review-of-the-literature-to-conceptualize-a-relevant-education-program
#6
REVIEW
Maxime Morsa, Rémi Gagnayre, Carole Deccache, Pierre Lombrail
OBJECTIVE: To give a comprehensive overview of the factors that influence the transition from pediatric services to adult care, and to conceptualize a relevant education program. METHOD: An evaluation grid was used to analyze the literature and classify factors depending on whether they were related to the patients, to the health care organization, to health care personnel, to the interaction between medical staff and patient, or to the illness and its treatment...
May 15, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28528340/evaluation-of-hypocaloric-diet-with-protein-supplementation-in-middle-aged-sarcopenic-obese-women-a-pilot-study
#7
Rosa Sammarco, Maurizio Marra, Maria Luisa Di Guglielmo, Marianna Naccarato, Franco Contaldo, Eleonora Poggiogalle, Lorenzo Maria Donini, Fabrizio Pasanisi
OBJECTIVE: The aim of this study was to evaluate the efficacy of a nutritional program, which is characterized by a different modulation of proteins, in adult patients with sarcopenic obesity. METHODS: We studied 18 obese women aged 41-74 years. Obesity was diagnosed as fat mass > 34.8% and sarcopenia was defined when lean body mass was <90% of the subject's ideal fat free mass. All subjects were randomly assigned to different nutritional interventions: Hypocaloric diet plus placebo (A) and hypocaloric high-protein diet (1...
May 20, 2017: Obesity Facts
https://www.readbyqxmd.com/read/28528208/mentoring-interventions-and-the-impact-of-protective-assets-on-the-reproductive-health-of-adolescent-girls-and-young-women
#8
REVIEW
Kate F Plourde, Nicole B Ippoliti, Geeta Nanda, Donna R McCarraher
Adolescent girls and young women (AGYW) are disproportionately affected by HIV and AIDS and other negative reproductive health (RH) outcomes. Emerging evidence suggests that programs to build AGYW's assets can help reduce their vulnerability to poor RH. Mentoring interventions have demonstrated a positive impact on a variety of youth development outcomes, including the protective assets needed to circumvent poor RH outcomes. The purpose of this review was to understand the types of mentoring programs for AGYW that have demonstrated effectiveness in improving protective assets, and/or, RH knowledge, intentions, behaviors, or outcomes themselves...
May 17, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28526974/the-health-equity-scholars-program-innovation-in-the-leaky-pipeline
#9
Carole C Upshur, Diedra M Wrighting, Gonzalo Bacigalupe, Joan Becker, Laura Hayman, Barbara Lewis, Sylvia Mignon, Megan E Rokop, Elizabeth Sweet, Marie Idali Torres, Paul Watanabe, Cedric Woods
Despite attempts to increase enrollment of under-represented minorities (URMs: primarily Black/African American, Hispanic/Latino, and Native American students) in health professional programs, limited progress has been made. Compelling reasons to rectify this situation include equity for URMs, better prepared health professionals when programs are diverse, better quality and access to health care for UMR populations, and the need for diverse talent to tackle difficult questions in health science and health care delivery...
May 19, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28526380/comparison-between-two-assessment-tools-for-fruit-and-vegetable-intake-relative-to-the-24-h-recall
#10
Mariana Souza Lopes, Luana Caroline Dos Santos, Aline Cristine Souza Lopes, Mery Natali Silva Abreu
OBJECTIVE: The aim of this study was to evaluate the validity of methods assessing fruit and vegetable (FV) intake among Brazilian users of the Primary Attention Health Care Program. METHODS: The present study included 299 participants (age ≥20 y) from a representative sample from a randomized controlled community trial performed as part of a health promotion program in a Brazilian metropolis. All participants completed three methods for the assessment of FV consumption: brief questionnaire of FV (QBrief-FV), food frequency questionnaire of FV, and a 24-h dietary recall...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28525464/the-cardiac-rehabilitation-model-improves-fitness-quality-of-life-and-depression-in-breast-cancer-survivors
#11
Lianne B Dolan, Danielle Barry, Teresa Petrella, Lindsay Davey, Ann Minnes, Allison Yantzi, Susan Marzolini, Paul Oh
PURPOSE: Exercise is a demonstrated, therapeutic strategy for cancer survivors to minimize many treatment-induced side effects and may decrease risk of recurrence. Nonetheless, structured programs that combine exercise and education are not yet standardized within cancer care. The Health, Exercise, Active Living, Therapeutic lifestyle (HEALTh) program is a clinical exercise program based on the established cardiac rehabilitation model, but customized for female breast cancer survivors...
May 18, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28525312/evaluation-of-the-introduction-of-an-e-health-skills-component-for-dietetics-students
#12
Megan E Rollo, Clare E Collins, Lesley MacDonald-Wicks
BACKGROUND: Appropriate and effective use of technology within practice is a key competency outlined in Australian dietetics training standards. An e-health skills component (lecture and workshop) was introduced to undergraduate students enrolled in an Australian nutrition and dietetics program. METHODS: The lecture orientated students to key e-health terms and concepts relating to telehealth and m-health technologies, while the workshop provided an opportunity to apply knowledge...
May 19, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28523517/body-size-of-male-youth-soccer-players-1978-2015
#13
REVIEW
Robert M Malina, António J Figueiredo, Manuel J Coelho-E-Silva
BACKGROUND: Studies of the body size and proportions of athletes have a long history. Comparisons of athletes within specific sports across time, though not extensive, indicate both positive and negative trends. OBJECTIVE: To evaluate secular variation in heights and weights of male youth soccer players reported in studies between 1978 and 2015. METHODS: Reported mean ages, heights, and weights of male soccer players 9-18 years of age were extracted from the literature and grouped into two intervals: 1978-99 and 2000-15...
May 18, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28523476/impact-of-a-patient-navigator-program-on-hospital-based-and-outpatient-utilization-over-180%C3%A2-days-in-a-safety-net-health-system
#14
Richard B Balaban, Fang Zhang, Catherine E Vialle-Valentin, Alison A Galbraith, Marguerite E Burns, Marc R Larochelle, Dennis Ross-Degnan
BACKGROUND: With emerging global payment structures, medical systems need to understand longer-term impacts of care transition strategies. OBJECTIVE: To determine the effect of a care transition program using patient navigators (PNs) on health service utilization among high-risk safety-net patients over a 180-day period. DESIGN: Randomized controlled trial conducted October 2011 through April 2013. PARTICIPANTS: Patients admitted to the general medicine service with ≥1 readmission risk factor: (1) age ≥ 60; (2) in-network inpatient admission within prior 6 months; (3) index length of stay ≥ 3 days; or (4) admission diagnosis of heart failure or (5) chronic obstructive pulmonary disease...
May 18, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28523066/framework-for-an-effective-assessment-from-rocky-roads-to-silk-route
#15
Zarrin Seema Siddiqui
A defensible assessment is the cornerstone of health professions education and requires a careful approach from all the stakeholders involved in designing and delivering the curriculum. In this article, a framework is described using four essential attributes that define an effective assessment. These attributes include orientation and clarification of expectations for both faculty and students followed by a well-structured learning experience and constant evaluation of the assessment program.
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28522894/interventional-audiology-to-address-hearing-health-care-disparities-oyendo-bien-pilot-study
#16
REVIEW
Nicole Marrone, Maia Ingram, Maria Somoza, Daisey Sánchez Jacob, Adriana Sanchez, Stephanie Adamovich, Frances P Harris
Interventional audiology, specifically community-based outreach, can connect people with the hearing health care system. Community-based participatory research methods were applied in two phases of research to: (1) investigate the needs of families affected by hearing loss in a rural Arizona community on the U.S.-Mexico border; and (2) evaluate an outreach program on hearing health. The needs assessment included interviews with persons with hearing loss and focus groups with family members and the greater community...
May 2017: Seminars in Hearing
https://www.readbyqxmd.com/read/28522410/a-global-human-health-risk-assessment-for-octamethylcyclotetrasiloxane-d4
#17
Robinan Gentry, Allison Franzen, Cynthia Van Landingham, Tracy Greene, Kathy Plotzke
Octamethylcyclotetrasiloxane (D4) is a low-molecular-weight volatile cyclic siloxane, primarily used as an intermediate in the production of some widely-used industrial and consumer silicone based polymers and may be present as a component in a variety of consumer products. A global "harmonized" risk assessment was conducted to meet requirements for substance-specific risk assessments conducted by regulatory agencies such as USEPA's Integrated Risk Information System (IRIS), Health Canada's Chemical Management Program (CMP) and various independent scientific committees of the European Commission (e...
May 15, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28521740/going-to-scale-design-and-implementation-challenges-of-a-program-to-increase-access-to-skilled-birth-attendants-in-nigeria
#18
Edward N Okeke, Emma Pitchforth, Josephine Exley, Peter Glick, Isa Sadeeq Abubakar, Amalavoyal V Chari, Usman Bashir, Kun Gu, Obinna Onwujekwe
BACKGROUND: The lack of availability of skilled providers in low- and middle- income countries is considered to be an important barrier to achieving reductions in maternal and child mortality. However, there is limited research on programs increasing the availability of skilled birth attendants in developing countries. We study the implementation of the Nigeria Midwives Service Scheme, a government program that recruited and deployed nearly 2,500 midwives to rural primary health care facilities across Nigeria in 2010...
May 18, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28521721/the-importance-of-military-conscripts-for-surveillance-of-human-immunodeficiency-virus-infection-and-risk-behavior-in-thailand
#19
Aladdin Shadyab, Kenrad Nelson, Ram Rangsin
BACKGROUND: The epidemic of human immunodeficiency virus (HIV) infection in Thailand began in 1988 among injection drug users (IDUs) in Bangkok. It soon spread to other populations, especially female sex workers (FSWs) and men attending STD clinics. Routine serologic surveillance for HIV began among military conscripts in 1991. The HIV seroprevalence data from military conscripts provided national surveillance data, since the entire population of 21 year old men were conscripted for 2 years' service in the military by a random process during which 10% of men were selected...
May 17, 2017: Current HIV Research
https://www.readbyqxmd.com/read/28521369/assistance-to-normal-delivery-in-two-public-maternities-perception-of-the-health-professionals
#20
Nayara Rodrigues Gomes de Oliveira, Thaís Rocha Assis, Waldemar Naves do Amaral, Valdivina Eterna Falone, Lívia Maria Oliveira Salviano
Purpose To evaluate the perception of health professionals involved in the labor process and the assistance to normal delivery, comparing two hospitals in the city of Goiânia, Brazil, regarding the perception of these professionals when they are performing the routines and practices recommended by the World Health Organization (WHO). Methods This is an analytical comparative study with a quantitative approach, performed in two public hospitals in the city of Goiânia, in the state of Goiás, Brazil. The study included 86 professionals working in assistance to immediate labor in two hospitals...
May 18, 2017: Revista Brasileira de Ginecologia e Obstetrícia
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