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https://www.readbyqxmd.com/read/29158427/do-emotions-related-to-alcohol-consumption-differ-by-alcohol-type-an-international-cross-sectional-survey-of-emotions-associated-with-alcohol-consumption-and-influence-on-drink-choice-in-different-settings
#1
Kathryn Ashton, Mark A Bellis, Alisha R Davies, Karen Hughes, Adam Winstock
OBJECTIVES: To examine the emotions associated with drinking different types of alcohol, explore whether these emotions differ by sociodemographics and alcohol dependency and whether the emotions associated with different drink types influence people's choice of drinks in different settings. DESIGN: International cross-sectional opportunistic survey (Global Drug Survey) using an online anonymous questionnaire in 11 languages promoted through newspapers, magazines and social media from November 2015 to January 2016...
November 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/29156939/phenolic-compounds-as-natural-and-multifunctional-anti-obesity-agents-a-review
#2
Celia Rodríguez-Pérez, Antonio Segura-Carretero, María Del Mar Contreras
Prevalence of obesity worldwide has reached pandemic proportions. Despite the increasing evidence in the implication of phenolic compounds in obesity management, the real effect is not completely understood. The available in vitro and in vivo studies have demonstrated the implication of phenolic compounds in: lowering food intake, decreasing lipogenesis, increasing lipolysis, stimulating fatty acids β-oxidation, inhibiting adipocyte differentiation and growth, attenuating inflammatory responses and suppress oxidative stress...
November 20, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29146365/sulfur-free-red-wines-through-the-use-of-grapevine-shoots-impact-on-the-wine-quality
#3
Rafaela Raposo, Fabio Chinnici, María José Ruiz-Moreno, Belén Puertas, Francisco J Cuevas, María Carbú, Raúl F Guerrero, Víctor Ortíz-Somovilla, José Manuel Moreno-Rojas, Emma Cantos-Villar
Following a preliminary study to determine the possibility of using a grapevine shoot extract (VIN) as a sustainable alternative to sulfur dioxide (SO2), in this study, the chromatic features, phenolic composition, and sensory analysis of wines treated with VIN at two concentrations were studied during storage in bottle for the first time. The highest differences were found in phenolic compounds after 12months of storage in bottle. The VIN wines had a low content of free anthocyanins and were high in vinyl-pyranoanthocyanins, and B-type vitisins...
March 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29146359/determination-of-tryptophan-derivatives-in-kynurenine-pathway-in-fermented-foods-using-liquid-chromatography-tandem-mass-spectrometry
#4
Cemile Yılmaz, Vural Gökmen
This study aimed to develop an analytical method for the determination of tryptophan and its derivatives in kynurenine pathway using tandem mass spectrometry in various fermented food products (bread, beer, red wine, white cheese, yoghurt, kefir and cocoa powder). The method entails an aqueous extraction and reversed phase chromatographic separation using pentafluorophenyl (PFP) column. It allowed quantitation of low ppb levels of tryptophan and its derivatives in different fermented food matrices. It was found that beer samples were found to contain kynurenine within the range of 28...
March 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29146332/micro-oxygenation-does-not-eliminate-hydrogen-sulfide-and-mercaptans-from-wine-it-simply-shifts-redox-and-complex-related-equilibria-to-reversible-oxidized-species-and-complexed-forms
#5
Eduardo Vela, Purificación Hernandez-Orte, Ernesto Franco-Luesma, Vicente Ferreira
This work seeks to assess the effects of micro-oxygenation (MOX) on the present and potential levels of Volatile Sulfur Compounds (VSCs) of wine. With such purpose, three red wines with a tendency to develop sulfury off-odors were subjected to three different MOX conditions (4.4-20mg/L delivered at 0.05 or 0.2mg/L/day). Samples were further subjected to Accelerated Reductive aging (AR) and analyzed for free and Brine Releasable (BR) VSCs and redox potential. Although MOX induced strong decreases in the levels of all free VSCs, hardly affected the ability of the wine to release back hydrogen sulfide and other mercaptans during AR-aging...
March 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29142647/effects-of-staining-liquids-and-finishing-methods-on-translucency-of-a-hybrid-ceramic-material-having-two-different-translucency-levels
#6
Sebnem Ulviye Buyukkaplan, Mehmet Mustafa Özarslan, Çağatay Barutcigil, Merve Arslan, Kubilay Barutcigil, Elif Ece Yoldan
PURPOSE: Beverages may affect the translucency of esthetic dental restorative materials. The aim of the present study was to investigate the effects of coffee and red wine on the translucency of a PICN material with two translucency levels, and finished with different methods. MATERIALS AND METHODS: 2M2 high translucent and translucent VITA Enamic hybrid ceramic blocks were investigated. Rectangular specimens with the dimensions of 12 mm × 14 mm × 2 mm were prepared...
October 2017: Journal of Advanced Prosthodontics
https://www.readbyqxmd.com/read/29129055/the-role-of-elemental-sulfur-in-forming-latent-precursors-of-h2s-in-wine
#7
Jillian A Jastrzembski, Rachel B Allison, Elle Friedberg, Gavin L Sacks
Hydrogen sulfide (H2S) can increase during abiotic storage of wines, and potential latent sources of H2S are still under investigation. We demonstrate that elemental sulfur (S(0)) residues on grapes can not only produce H2S during fermentation, but also form precursors capable of generating additional H2S after three months bottle storage. H2S could be released from S(0)-derived precursors by addition of a reducing agent (TCEP), but not by addition of strong brine, and the size of the TCEP-releasable pool varied among yeast strain...
November 12, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29120125/risk-factors-associated-with-black-tooth-stain
#8
Katica Prskalo, Eva Klarić Sever, Ivan Alerić, Tatjana Antonić Jelić, Ivona Žaja
The aim of the study was to show whether there is any influence of food, drink or drug intake on the formation of tooth discoloration. A total of 500 patients aged 15-25 years were examined to take part in the study. Of these, 60 patients were selected and divided into two groups of 30 patients each. Group 1 included patients with black pigmentation on vestibular/oral tooth surfaces. Group 2 included patients without discoloration (control). Data were recorded in a questionnaire. Atomic absorption spectrometry was used to determine elements in discoloration samples...
March 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29112113/erratum-carrasco-s%C3%A3-nchez-v-et-al-removal-of-4-ethylphenol-and-4-ethylguaiacol-with-polyaniline-based-compounds-in-wine-like-model-solutions-and-red-wine-molecules-2015-20-8-14312-14325
#9
Verónica Carrasco-Sánchez, Amalraj John, Adolfo Marican, Leonardo S Santos, V Felipe Laurie
No abstract text is available yet for this article.
November 7, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29105927/resveratrol-interferes-with-an-early-step-in-the-fibrillation-pathway-of-human-lysozyme-and-modulates-it-towards-less-toxic-off-pathway-aggregates
#10
Fatima Kamal Zaidi, Rajiv Bhat
Effect of the red wine polyphenol, resveratrol, was investigated on the amyloid fibril formation of human lysozyme (HuL), towards elucidating the mechanism of resveratrol action and probing its role as a possible modulator of lysozyme aggregation and toxicity. Using a number of biophysical tools, resveratrol was observed to alter the fibrillation kinetics of HuL and inhibit its fibrillation by binding with weak to moderate affinity to the conformations populated at the early stages of the pathway with concomitant stabilization of these initial conformations...
November 4, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/29084143/red-wine-resveratrol-and-atrial-fibrillation
#11
REVIEW
Laura Siga Stephan, Eduardo Dytz Almeida, Melissa Medeiros Markoski, Juliano Garavaglia, Aline Marcadenti
Atrial fibrillation (AF) is a common cardiac arrhythmia that is associated with increased risk for cardiovascular disease and overall mortality. Excessive alcohol intake is a well-known risk factor for AF, but this correlation is less clear with light and moderate drinking. Besides, low doses of red wine may acutely prolong repolarization and slow cardiac conduction. Resveratrol, a bioactive polyphenol found in grapes and red wine, has been linked to antiarrhythmic properties and may act as an inhibitor of both intracellular calcium release and pathological signaling cascades in AF, eliminating calcium overload and preserving the cardiomyocyte contractile function...
October 30, 2017: Nutrients
https://www.readbyqxmd.com/read/29074616/resveratrol-a-novel-type-of-topoisomerase-ii-inhibitor
#12
Joyce H Lee, Timothy J Wendorff, James M Berger
Resveratrol, a polyphenol found in various plant sources, has gained attention as a possible agent responsible for the purported health benefits of certain foods, such as red wine. Despite annual multi-million dollar market sales as a nutriceutical, there is little consensus about the physiological roles of resveratrol. One suggested molecular target of resveratrol is eukaryotic topoisomerase II (topo II), an enzyme essential for chromosome segregation and DNA supercoiling homeostasis. Interestingly, resveratrol is chemically similar to ICRF-187, a clinically-approved chemotherapeutic that stabilizes an ATP-dependent dimerization interface in topo II to block enzyme activity...
October 26, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29066884/trans-resveratrol-loaded-nonionic-lamellar-liquid-crystalline-systems-structural-rheological-mechanical-textural-and-bioadhesive-characterization-and-evaluation-of-in-vivo-anti-inflammatory-activity
#13
Bruno Fonseca-Santos, Cínthia Yuka Satake, Giovana Maria Fioramonti Calixto, Aline Martins Dos Santos, Marlus Chorilli
Resveratrol (Res) is a common phytoalexin present in a few edible materials, such as grape skin, peanuts, and red wine. Evidence has shown the beneficial effects of Res on human health, which may be attributed to its anti-inflammatory activity. However, the poor aqueous solubility of Res limits its therapeutic effectiveness. Therefore, the use of nanostructured delivery systems for Res, such as liquid-crystalline systems, could be beneficial. In this study, we aimed to develop, characterize, and determine the in vivo effectiveness of Res-loaded liquid-crystalline systems...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29055473/the-effect-of-alcohol-and-red-wine-consumption-on-clinical-and-mri-outcomes-in-multiple-sclerosis
#14
Camilo Diaz-Cruz, Alicia S Chua, Muhammad Taimur Malik, Tamara Kaplan, Bonnie I Glanz, Svetlana Egorova, Charles R G Guttmann, Rohit Bakshi, Howard L Weiner, Brian C Healy, Tanuja Chitnis
BACKGROUND: Alcohol and in particular red wine have both immunomodulatory and neuroprotective properties, and may exert an effect on the disease course of multiple sclerosis (MS). OBJECTIVE: To assess the association between alcohol and red wine consumption and MS course. METHODS: MS patients enrolled in the Comprehensive Longitudinal Investigation of Multiple Sclerosis at the Brigham and Women's Hospital (CLIMB) who completed a self-administered questionnaire about their past year drinking habits at a single time point were included in the study...
October 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29054583/dietary-resveratrol-increases-mid-life-fecundity-of-female-nothobranchius-guentheri
#15
Youngjoo Lee, Andrew C Drake, Nicholas O Thomas, Lindsey G Ferguson, Patrick E Chappell, Kate Petersen Shay
The decline of female reproductive function is an early phenotype of aging in humans, occurring only midway through the lifespan. Yet the number of women delaying pregnancy continues to rise in industrialized societies due to personal or socioeconomic circumstances, often resulting in subfertility or difficulty conceiving. There are few defined mechanisms associated with this etiology, and equally few effective therapies. To combat this problem, we used a novel emerging model, Nothobranchius guentheri, that recapitulates the age-associated spectrum of changes that adversely affect human fertility...
October 17, 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/29037742/augmentation-of-chemical-and-organoleptic-properties-in-syzygium-cumini-wine-by-incorporation-of-grape-seeds-during-vinification
#16
K S VenuGopal, Chris Cherita, K A Anu-Appaiah
The role of grape seed tannins on improving organoleptic properties and its involvement in color stabilization in red wine are well established. The addition of grape seeds as the source of condensed tannins in fruit wine may provide a solution for its color instability and improvement of sensory attributes. Syzgium cumini is traditionally known for its therapeutic properties. In the current study, the influence of yeasts and grape seed addition during fermentation on the chromatic, phenolic and sensory attributes of the wine was accessed...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29037734/reducing-the-negative-sensory-impact-of-volatile-phenols-in-red-wine-with-different-chitosans-effect-of-structure-on-efficiency
#17
Luís Filipe-Ribeiro, Fernanda Cosme, Fernando M Nunes
"Brett character" is a negative sensory attribute acquired by red wines when contaminating Dekkera/Brettanomyces yeasts produce 4-ethylphenol and 4-ethylguaiacol, known as volatile phenols (VPs), from cinnamic acid precursors. In this study, chitins and chitosans with different structural features, namely deacetylation degree (5-91%) and molecular weight (24-466kDa) were used for the reduction of this sensory defect. Chitins and chitosans decreased 7-26% of the headspace abundance of VPs without changing their amounts in wines...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29037718/co-fermentation-of-red-grapes-and-white-pomace-a-natural-and-economical-process-to-modulate-hybrid-wine-composition
#18
Paméla Nicolle, Charlène Marcotte, Paul Angers, Karine Pedneault
The impact of co-fermenting white grape pomace (WP) and red grape pomace (RP) on the composition of interspecific hybrid wine was studied using the Vitis sp. 'Frontenac' and 'Vidal'. The proanthocyanidin and anthocyanin content of the resulting wines were analysed by HPLC-fluorescence and UPLC-MS/MS, respectively. The CIELAB parameters and volatile compounds were analysed using spectrophotometry-UV and GC-MS-SPME, respectively. The WP addition increased the concentration of monomeric and oligomeric flavan-3-ols, and terpenes in the wines...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29036903/resveratrol-and-amyloid-beta-mechanistic-insights
#19
REVIEW
Yongming Jia, Na Wang, Xuewei Liu
The amyloid-beta (Aβ) hypothesis that dyshomeostasis between Aβ production and clearance is a very early, key molecular factor in the etiology of Alzheimer's disease (AD) has been proposed and examined in the AD research field. Scientists have focused on seeking natural products or drugs to influence the dynamic equilibrium of Aβ, targeting production and clearance of Aβ. There is emerging evidence that resveratrol (Res), a naturally occurring polyphenol mainly found in grapes and red wine, acts on AD in numerous in vivo and in vitro models...
October 14, 2017: Nutrients
https://www.readbyqxmd.com/read/29035613/quercetin-induced-amp-activated-protein-kinase-activation-attenuates-vasoconstriction-through-lkb1-ampk-signaling-pathway
#20
Seul Gi Kim, Jae-Ryong Kim, Hyoung Chul Choi
The vascular tone plays an important role in blood pressure and flow. It is influenced by the contraction of vascular smooth muscle cells (VSMCs), which in turn is regulated by the balance between the myosin light chain kinase (MLCK) and the phosphorylated myosin light chain (p-MLC). Quercetin is a common flavonoid which is found in many fruits and red wine. Although quercetin has been widely reported to be involved in cell proliferation, migration, and apoptosis in VSMCs, it has not yet been demonstrated whether quercetin is related to vasocontraction, a function regulated by the AMP-activated protein kinase (AMPK) signaling pathway...
October 16, 2017: Journal of Medicinal Food
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