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https://www.readbyqxmd.com/read/29781715/andrographolide-exhibits-anticancer-potential-against-human-colon-cancer-cells-by-inducing-cell-cycle-arrest-and-programmed-cell-death-via-augmentation-of-intracellular-reactive-oxygen-species-level
#1
Imran Khan, Fahad Khan, Arshi Farooqui, Irfan A Ansari
Andrographolide, a diterpenoid lactone and a major constituent of Andrographis paniculata Nees, exhibits remarkable anticancer activity. However, the effect of andrographolide on colon cancer has not been completely elucidated yet. Thus, we investigated the chemopreventive potential of andrographolide in colon cancer HT-29 cells. The cytotoxic potential of andrographolide on HT-29 cells was determined by MTT assay, trypan blue exclusion assay, colony formation assay, and morphological analysis; and apoptotic property by DAPI and Hoechst staining, FITC-Annexin V assay, DNA fragmentation assay and caspase-3 activity assay...
May 21, 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29768372/technologies-for-participatory-medicine-and-health-promotion-in-the-elderly-population
#2
Laura Nieto-Riveiro, Betania Groba, M Carmen Miranda, Patricia Concheiro, Alejandro Pazos, Thais Pousada, Javier Pereira
INTRODUCTION: The progressive aging of the population is a socio-demographic phenomenon experienced by most countries in the world in recent decades, especially in Japan and in many European Union countries. During this process, so-called "geriatric syndromes" frequently occur. The focus of this study is the quality of life of the elderly in relation to these 3 factors: risk of falls, urinary incontinence, and insomnia. OBJECTIVE: The main purpose is to determine the impact of a multifactorial intervention program implemented with institutionalized elderly people...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29765699/feasibility-and-effects-of-a-home-based-intervention-using-activity-trackers-on-achievement-of-individual-goals-quality-of-life-and-motor-performance-in-patients-with-paediatric-cancer
#3
Miriam Götte, Sabine Verena Kesting, Joachim Gerss, Dieter Rosenbaum, Joachim Boos
Objectives: Supervised exercise interventions during inpatient care are feasible. The objective was to evaluate the usability of activity trackers and centralised monitoring to conduct a home-based exercise intervention during cancer treatment. The primary endpoint and confirmatory analysis was achievement of individual goals for daily steps, compared (A) in the intervention group (IG) over time and (B) between the IG and control group (CG). Secondary endpoints included achievement of goals for active minutes and effects on motor performance and health-related quality of life (hrQoL)...
2018: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29765585/a-study-of-the-effects-of-daily-physical-activity-on-memory-and-attention-capacities-in-college-students
#4
Dinh-Van Phan, Chien-Lung Chan, Ren-Hao Pan, Nan-Ping Yang, Hsiu-Chen Hsu, Hsien-Wei Ting, K Robert Lai
This study evaluated the relationship between daily physical activity (DPA) and memory capacity, as well as the association between daily activity and attention capacity, in college students in Taiwan. Participants (mean age = 20.79) wore wearable trackers for 106 days in order to collect DPA. These data were analyzed in association with their memory and attention capacities, as assessed using the spatial span test (SST) and the trail making test (TMT). The study showed significant negative correlations between memory capacity, time spent on the attention test (TSAT), calories burnt, and very active time duration (VATD) on the day before testing ( r = -0...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29764614/use-and-physiological-responses-of-portable-dynamic-office-workstations-in-an-occupational-setting-a-field-study
#5
Vera Schellewald, Jens Kleinert, Rolf Ellegast
OBJECTIVE: The aim of this study was to investigate the use of two types of dynamic workstations (Deskbike, activeLife Trainer) and their effects on physiological activation in an occupational setting. METHODS: 30 employees were given access to the devices for 28 days. Frequency and duration of borrowing and use was recorded by a Chipcard-system. Physiological activation (energy expenditure, heart rate) while working in a seated position and using the workstations was measured with the activity tracker Fitbit Charge HR...
September 2018: Applied Ergonomics
https://www.readbyqxmd.com/read/29754647/effects-of-a-12-week-mhealth-program-on-peak-vo-2-and-physical-activity-patterns-after-completing-cardiac-rehabilitation-a-randomized-controlled-trial
#6
Brian D Duscha, Lucy W Piner, Mahesh P Patel, Karen P Craig, Morgan Brady, Robert W McGarrah, Connie Chen, William E Kraus
BACKGROUND: Site-based cardiac rehabilitation (CR) provides supervised exercise, education and motivation for patients. Graduates of CR have improved exercise tolerance. However, when participation in CR ceases, adherence to regular physical activity often declines, consequently leading to worsening risk factors and clinical events. Therefore, the purpose of this pilot study was to evaluate if a mHealth program could sustain the fitness and physical activity levels gained during CR. METHODS AND RESULTS: A 12-week mHealth program was implemented using physical activity trackers and health coaching...
May 2018: American Heart Journal
https://www.readbyqxmd.com/read/29751887/integrating-activity-spaces-in-health-research-comparing-the-veritas-activity-space-questionnaire-with-7-day-gps-tracking-and-prompted-recall
#7
Yan Kestens, Benoit Thierry, Martine Shareck, Madeleine Steinmetz-Wood, Basile Chaix
BACKGROUND: Accounting for daily mobility allows assessment of multiple exposure to environments. This study compares spatial data obtained (i) from an interactive map-based questionnaire on regular activity locations (VERITAS) and (ii) from GPS tracking. METHODS: 234 participants of the RECORD GPS Study completed the VERITAS questionnaire and wore a GPS tracker for 7 days. Analyses illustrate the spatial match between both datasets. RESULTS: For half of the sample, 85...
June 2018: Spatial and Spatio-temporal Epidemiology
https://www.readbyqxmd.com/read/29748160/engagement-strategies-for-self-monitoring-symptoms-of-bipolar-disorder-with-mobile-and-wearable-technology-protocol-for-a-randomized-controlled-trial
#8
Amy Cochran, Livia Belman-Wells, Melvin McInnis
BACKGROUND: Monitoring signs and symptoms in bipolar disorder (BP) is typically based on regular assessments from patient-clinician interactions. Mobile and wearable technology promises to make monitoring symptoms in BP easier, but little is known about how best to engage individuals with BP in monitoring symptoms. OBJECTIVE: The objective of this study was to provide the rationale and protocol for a randomized controlled trial that investigates engagement strategies for monitoring symptoms of BP, including the strategies of using activity trackers compared with self-reports and reviewing recorded symptoms weekly with an interviewer...
May 10, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29743026/the-effectiveness-of-an-online-intervention-in-preventing-excessive-gestational-weight-gain-the-e-moms-roc-randomized-controlled-trial
#9
Christine M Olson, Susan W Groth, Meredith L Graham, Jennifer E Reschke, Myla S Strawderman, Isabel Diana Fernandez
BACKGROUND: Excessive gestational weight gain (GWG) is common and contributes to the development of obesity in women and their offspring. Electronic or e-health interventions have the potential to reach large groups of women and prevent excessive GWG, but their effectiveness has not been demonstrated. The purpose of this study was to evaluate, in a real-world setting, the effectiveness of a self-directed, integrated online and mobile phone behavioral intervention in preventing excessive GWG...
May 9, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29742550/self-tracking-of-physical-activity-in-people-with-type-2-diabetes-a-randomized-controlled-trial
#10
Thea J M Kooiman, Martijn de Groot, Klaas Hoogenberg, Wim P Krijnen, Cees P van der Schans, Adriaan Kooy
The purpose of this study was to determine the efficacy of an online self-tracking program on physical activity, glycated hemoglobin, and other health measures in patients with type 2 diabetes. Seventy-two patients with type 2 diabetes were randomly assigned to an intervention or control group. All participants received usual care. The intervention group received an activity tracker (Fitbit Zip) connected to an online lifestyle program. Physical activity was analyzed in average steps per day from week 0 until 12...
May 4, 2018: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/29740595/dynamic-encoding-of-incentive-salience-in-the-ventral-pallidum-dependence-on-the-form-of-the-reward-cue
#11
Allison M Ahrens, Lindsay M Ferguson, Terry E Robinson, J Wayne Aldridge
Some rats are especially prone to attribute incentive salience to a cue (conditioned stimulus, CS) paired with food reward (sign-trackers, STs), but the extent they do so varies as a function of the form of the CS. Other rats respond primarily to the predictive value of a cue (goal-trackers, GTs), regardless of its form. Sign-tracking is associated with greater cue-induced activation of mesolimbic structures than goal-tracking; however, it is unclear how the form of the CS itself influences activity in neural systems involved in incentive salience attribution...
March 2018: ENeuro
https://www.readbyqxmd.com/read/29729611/accuracy-of-wearable-physical-activity-trackers-in-people-with-parkinson-s-disease
#12
Robyn M Lamont, Hannah L Daniel, Caitlyn L Payne, Sandra G Brauer
INTRODUCTION: The purpose of this study was to determine the accuracy of the Fitbit Charge HR™ and Garmin vívosmart® HR in measuring steps and reflecting intensity of activity in people with Parkinson's disease (PD). METHODS: Thirty-three people with mild-moderate PD performed six, two-minute indoor walks at their self-selected walking pace, and at target cadences of 60, 80, 100, 120 and 140 beats/min. A 500 m outdoor walk with terrain challenges was also performed...
April 24, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29724191/reliability-and-validity-of-two-fitness-tracker-devices-in-the-laboratory-and-home-environment-for-older-community-dwelling-people
#13
Elissa Burton, Keith D Hill, Nicola T Lautenschlager, Cecilie Thøgersen-Ntoumani, Gill Lewin, Eileen Boyle, Erin Howie
BACKGROUND: Two-thirds of older Australians are sedentary. Fitness trackers have been popular with younger people and may encourage older adults to become more active. Older adults may have different gait patterns and as such it is important to establish whether fitness trackers are valid and reliable for this population. The aim of the study was to test the reliability and validity of two fitness trackers (Fitbit Flex and ChargeHR) by step count when worn by older adults. Reliability and validity were tested in two conditions: 1) in the laboratory using a two-minute-walk-test (2MWT) and 2) in a free-living environment...
May 3, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29720359/diffusion-of-the-digital-health-self-tracking-movement-in-canada-results-of-a-national-survey
#14
Guy Paré, Chad Leaver, Claire Bourget
BACKGROUND: With the ever-increasing availability of mobile apps, consumer wearables, and smart medical devices, more and more individuals are self-tracking and managing their personal health data. OBJECTIVE: The aim of this study was to investigate the diffusion of the digital self-tracking movement in Canada. It provides a comprehensive, yet detailed account of this phenomenon. It examines the profile of digital self-trackers, traditional self-trackers, and nontrackers, further investigating the primary motivations for self-tracking and reasons for nontracking; barriers to adoption of connected care technologies; users' appreciation of their self-tracking devices, including what they perceive to be the main benefits; factors that influence people's intention to continue using connected care technologies in the future; and the reasons for usage discontinuance...
May 2, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29718452/accuracy-of-activity-trackers-in-parkinson-disease-should-we-prescribe-them
#15
Nicholas Wendel, Chelsea E Macpherson, Karoline Webber, Kathryn Hendron, DeAngelis Tamara, Colon-Semenza Cristina, Terry Ellis
Background: Wearable, consumer-grade activity trackers have become widely available as a means of monitoring physical activity in the form of step counts. However, step counts may not be accurate in persons with Parkinson disease (PD) due to atypical gait characteristics. Objective: This study aimed to investigate the accuracy of 4 consumer-grade activity trackers in individuals with PD while ambulating during continuous and discontinuous walking tasks. Design: This study used a cross-sectional design...
April 30, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29709718/commonly-available-activity-tracker-apps-and-wearables-as-a-mental-health-outcome-indicator-a-prospective-observational-cohort-study-among-young-adults-with-psychological-distress
#16
Alissa Knight, Niranjan Bidargaddi
BACKGROUND: Monitoring is integral to adequately recognise and track mental health indicators of symptoms and functioning. Early identification of warning signs from digital footprints could facilitate adaptive and dynamic just in-time monitoring and care for individuals with common mental disorders. METHODS: Self-report data on mental health and lifestyle behaviour from 120 male and female Australian young adults experiencing psychological distress were collected online...
April 22, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29704922/the-validity-and-reliability-of-consumer-grade-activity-trackers-in-older-community-dwelling-adults-a-systematic-review
#17
REVIEW
Nicola Straiton, Muaddi Alharbi, Adrian Bauman, Lis Neubeck, Janice Gullick, Ravinay Bhindi, Robyn Gallagher
OBJECTIVE: To understand the validity and reliability of consumer-grade activity trackers (consumer wearables) in older, community-dwelling adults. METHODS: A systematic review of studies involving adults aged over 65 years who underwent physical activity monitoring with consumer wearables. A total of 7 observational studies qualified, identified from electronic databases: MEDLINE, EMBASE, Cochrane Library and others (2014-2018). Validity was interpreted using correlation coefficients (CC) and percentage error for agreement between reference devices or gold-standard validation methods Reliability was compared using mean differences or ranges (under- or overestimation) of step count and activity time...
June 2018: Maturitas
https://www.readbyqxmd.com/read/29690816/is-motor-activity-during-cognitive-assessment-an-indicator-for-feigned-attention-deficit-hyperactivity-disorder-adhd-in-adults
#18
Anselm B M Fuermaier, Oliver Tucha, Janneke Koerts, Tabea S Send, Matthias Weisbrod, Steffen Aschenbrenner, Lara Tucha
OBJECTIVES: Several approaches, ranging from self-ratings of symptoms and impairments to objective neuropsychological testing, have been utilized during clinical evaluation in order to assess symptom and performance validity of individuals with attention-deficit/hyperactivity disorder (ADHD) in adulthood. Motor activity has not been considered yet in this context, which is surprising given that hyperactivity is a prominent characteristic of ADHD. Hence, the goal of the present study was to explore the incremental value of motor activity when assessing the credibility of individuals with adult ADHD at clinical evaluation...
April 25, 2018: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/29669703/physical-activity-sedentary-behavior-and-diet-related-ehealth-and-mhealth-research-bibliometric-analysis
#19
REVIEW
Andre Matthias Müller, Carol A Maher, Corneel Vandelanotte, Melanie Hingle, Anouk Middelweerd, Michael L Lopez, Ann DeSmet, Camille E Short, Nicole Nathan, Melinda J Hutchesson, Louise Poppe, Catherine B Woods, Susan L Williams, Petra A Wark
BACKGROUND: Electronic health (eHealth) and mobile health (mHealth) approaches to address low physical activity levels, sedentary behavior, and unhealthy diets have received significant research attention. However, attempts to systematically map the entirety of the research field are lacking. This gap can be filled with a bibliometric study, where publication-specific data such as citations, journals, authors, and keywords are used to provide a systematic overview of a specific field...
April 18, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29650506/evaluating-the-validity-of-current-mainstream-wearable-devices-in-fitness-tracking-under-various-physical-activities-comparative-study
#20
Junqing Xie, Dong Wen, Lizhong Liang, Yuxi Jia, Li Gao, Jianbo Lei
BACKGROUND: Wearable devices have attracted much attention from the market in recent years for their fitness monitoring and other health-related metrics; however, the accuracy of fitness tracking results still plays a major role in health promotion. OBJECTIVE: The aim of this study was to evaluate the accuracy of a host of latest wearable devices in measuring fitness-related indicators under various seminatural activities. METHODS: A total of 44 healthy subjects were recruited, and each subject was asked to simultaneously wear 6 devices (Apple Watch 2, Samsung Gear S3, Jawbone Up3, Fitbit Surge, Huawei Talk Band B3, and Xiaomi Mi Band 2) and 2 smartphone apps (Dongdong and Ledongli) to measure five major health indicators (heart rate, number of steps, distance, energy consumption, and sleep duration) under various activity states (resting, walking, running, cycling, and sleeping), which were then compared with the gold standard (manual measurements of the heart rate, number of steps, distance, and sleep, and energy consumption through oxygen consumption) and calculated to determine their respective mean absolute percentage errors (MAPEs)...
April 12, 2018: JMIR MHealth and UHealth
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