Fatemeh Seifar, Edward J Fox, Anantharaman Shantaraman, Yue Liu, Eric B Dammer, Erica Modeste, Duc M Duong, Luming Yin, Adam N Trautwig, Qi Guo, Kaiming Xu, Lingyan Ping, Joseph S Reddy, Mariet Allen, Zachary Quicksall, Laura Heath, Jo Scanlan, Erming Wang, Minghui Wang, Abby Vander Linden, William Poehlman, Xianfeng Chen, Saurabh Baheti, Charlotte Ho, Thuy Nguyen, Geovanna Yepez, Adriana O Mitchell, Stephanie R Oatman, Xue Wang, Minerva M Carrasquillo, Alexi Runnels, Thomas Beach, Geidy E Serrano, Dennis W Dickson, Edward B Lee, Todd E Golde, Stefan Prokop, Lisa L Barnes, Bin Zhang, Varham Haroutunian, Marla Gearing, James J Lah, Philip De Jager, David A Bennett, Anna Greenwood, Nilüfer Ertekin-Taner, Allan I Levey, Aliza Wingo, Thomas Wingo, Nicholas T Seyfried
INTRODUCTION: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease, yet our comprehension predominantly relies on studies within the non-Hispanic White (NHW) population. Here we aimed to provide comprehensive insights into the proteomic landscape of AD across diverse racial and ethnic groups. METHODS: Dorsolateral prefrontal cortex (DLPFC) and superior temporal gyrus (STG) brain tissues were donated from multiple centers (Mayo Clinic, Emory University, Rush University, Mt...
April 26, 2024: bioRxiv