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https://www.readbyqxmd.com/read/29786573/analysis-of-electromyographic-indexes-of-temporal-and-masticatory-muscles-in-patients-with-distal-occlusion-complicated-by-dental-crowding
#1
Maryna I Dmytrenko
OBJECTIVE: Introduction: Rate of distal occlusion (up to 40%) and dental crowding (up to 65%) is the largest in the structure of orthodontic pathology. The aim of the study was to investigate bioelectrical activity of temporal and masticatory muscles and to set parameters of electromyographic indexes in patients with distal occlusion and dental crowding in permanent occlusion. PATIENTS AND METHODS: Materials and methods: Bioelectrical activity of temporal and masticatory muscles in 11 patients aged 16-24 years was determined before orthodontic treatment...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29785510/measuring-translational-diffusion-of-15-n-enriched-biomolecules-in-complex-solutions-with-a-simplified-1-h-15-n-hmqc-filtered-best-sequence
#2
Shenggen Yao, Thomas G Meikle, Ashish Sethi, Frances Separovic, Jeffrey J Babon, David W Keizer
Pulsed-field gradient nuclear magnetic resonance has seen an increase in applications spanning a broad range of disciplines where molecular translational diffusion properties are of interest. The current study introduces and experimentally evaluates the measurement of translational diffusion coefficients of 15 N-enriched biomolecules using a 1 H-15 N HMQC-filtered band-selective excitation short transient (BEST) sequence as an alternative to the previously described SOFAST-XSTE sequence. The results demonstrate that accurate translational diffusion coefficients of 15 N-labelled peptides and proteins can be obtained using this alternative 1 H-15 N HMQC-filtered BEST sequence which is implementable on NMR spectrometers equipped with probes fitted with a single-axis field gradient, including most cryoprobes dedicated to bio-NMR...
May 21, 2018: European Biophysics Journal: EBJ
https://www.readbyqxmd.com/read/29784009/crowd-figure-pictograms-improve-women-s-knowledge-about-mammography-screening-results-from-a-randomised-controlled-trial
#3
Maren Reder, Lau Caspar Thygesen
OBJECTIVE: To evaluate the effect of crowd-figure-pictograms on women's numeric knowledge about mammography screening in a three-armed parallel randomised controlled trial. RESULTS: 552 women were randomised to receive (1) non-numeric information (n = 192), (2) non-numeric and numeric information (n = 186), or (3) non-numeric and numeric information complemented by crowd-figure-pictograms (n = 174). Baseline numeric knowledge was low (control 0.61, numeric 0.66, and pictogram 0...
May 21, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29783212/changes-in-biochemical-parameters-of-oral-fluid-in-patients-during-the-orthodontic-treatment-with-a-bracket-system-under-the-action-of-a-developed-mucosal-gel-with-probiotic
#4
Anna V Voronkova, Lyubov V Smaglyuk
OBJECTIVE: Introduction: Many research studies involving orthodontic patients focus on changes in levels of oral microbiocenosis after bracket placement. Based upon this the objective of the current study was to determine the effect of the developed mucosal gel with probiotics on the biochemical parameters of the oral fluid of patients during the orthodontic treatment with a bracket system. The aim: Aim of our study is to determine the effect of the developed mucosal gel with probiotics on the biochemical parameters of the oral fluid of patients during the orthodontic treatment with a bracket system...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782491/community-based-benchmarking-improves-spike-rate-inference-from-two-photon-calcium-imaging-data
#5
Philipp Berens, Jeremy Freeman, Thomas Deneux, Nicolay Chenkov, Thomas McColgan, Artur Speiser, Jakob H Macke, Srinivas C Turaga, Patrick Mineault, Peter Rupprecht, Stephan Gerhard, Rainer W Friedrich, Johannes Friedrich, Liam Paninski, Marius Pachitariu, Kenneth D Harris, Ben Bolte, Timothy A Machado, Dario Ringach, Jasmine Stone, Luke E Rogerson, Nicolas J Sofroniew, Jacob Reimer, Emmanouil Froudarakis, Thomas Euler, Miroslav Román Rosón, Lucas Theis, Andreas S Tolias, Matthias Bethge
In recent years, two-photon calcium imaging has become a standard tool to probe the function of neural circuits and to study computations in neuronal populations. However, the acquired signal is only an indirect measurement of neural activity due to the comparatively slow dynamics of fluorescent calcium indicators. Different algorithms for estimating spike rates from noisy calcium measurements have been proposed in the past, but it is an open question how far performance can be improved. Here, we report the results of the spikefinder challenge, launched to catalyze the development of new spike rate inference algorithms through crowd-sourcing...
May 21, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29781413/drivers-potentially-influencing-host-bat-fly-interactions-in-anthropogenic-neotropical-landscapes-at-different-spatial-scales
#6
Jacqueline Hernández-Martínez, Juan B Morales-Malacara, Mariana Yolotl Alvarez-Añorve, Sergio Amador-Hernández, Ken Oyama, Luis Daniel Avila-Cabadilla
The anthropogenic modification of natural landscapes, and the consequent changes in the environmental conditions and resources availability at multiple spatial scales can affect complex species interactions involving key-stone species such as bat-parasite interactions. In this study, we aimed to identify the drivers potentially influencing host-bat fly interactions at different spatial scales (at the host, vegetation stand and landscape level), in a tropical anthropogenic landscape. For this purpose, we mist-netted phyllostomid and moormopid bats and collected the bat flies (streblids) parasitizing them in 10 sites representing secondary and old growth forest...
May 21, 2018: Parasitology
https://www.readbyqxmd.com/read/29780538/competition-between-li-and-na-in-sodium-transporters-and-receptors-which-na-binding-sites-are-therapeutic-li-targets
#7
Todor Dudev, Karine Mazmanian, Carmay Lim
Sodium (Na+ ) acts as an indispensable allosteric regulator of the activities of biologically important neurotransmitter transporters and G-protein coupled receptors (GPCRs), which comprise well-known drug targets for psychiatric disorders and addictive behavior. How selective these allosteric Na+ -binding sites are for the cognate cation over abiogenic Li+ , a first-line drug to treat bipolar disorder, is unclear. Here, we reveal how properties of the host protein and its binding cavity affect the outcome of the competition between Li+ and Na+ for allosteric binding sites in sodium transporters and receptors...
May 7, 2018: Chemical Science
https://www.readbyqxmd.com/read/29777705/membrane-proteins-significantly-restrict-exosome-mobility
#8
Mikhail Skliar, Vasiliy S Chernyshev, David M Belnap, German V Sergey, Samer M Al-Hakami, Philip S Bernard, Inge J Stijleman, Rakesh Rachamadugu
Exosomes are membrane nanovesicles implicated in cell-to-cell signaling in which they transfer their molecular cargo from the parent to the recipient cells. This role essentially depends on the exosomes' small size, which is the prerequisite for their rapid migration through the crowded extracellular matrix and into and out of circulation. Here we report much lower exosome mobility than expected from the size of their vesicles, implicate membrane proteins in a substantially impeded rate of migration, and suggest an approach to quantifying the impact...
May 16, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29776091/modeling-persistence-of-motion-in-a-crowded-environment-the-diffusive-limit-of-excluding-velocity-jump-processes
#9
Enrico Gavagnin, Christian A Yates
Persistence of motion is the tendency of an object to maintain motion in a direction for short time scales without necessarily being biased in any direction in the long term. One of the most appropriate mathematical tools to study this behavior is an agent-based velocity-jump process. In the absence of agent-agent interaction, the mean-field continuum limit of the agent-based model (ABM) gives rise to the well known hyperbolic telegraph equation. When agent-agent interaction is included in the ABM, a strictly advective system of partial differential equations (PDEs) can be derived at the population level...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776087/effect-of-form-of-obstacle-on-speed-of-crowd-evacuation
#10
Ryosuke Yano
This paper investigates the effect of the form of an obstacle on the time that a crowd takes to evacuate a room, using a toy model. Pedestrians are modeled as active soft matter moving toward a point with intended velocities. An obstacle is placed in front of the exit, and it has one of four shapes: a cylindrical column, a triangular prism, a quadratic prism, or a diamond prism. Numerical results indicate that the evacuation-completion time depends on the shape of the obstacle. Obstacles with a circular cylinder (C...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29775897/the-gastric-mucosal-protective-effects-of-astragaloside-iv-in-mnng-induced-gpl-rats
#11
Tiantian Cai, Chengzhe Zhang, Ziming Zhao, Siyi Li, Haobin Cai, Xiaodong Chen, Dake Cai, Wei Liu, Yan Yan, Kaifeng Xie, Huafeng Pan, Xiaohui Zeng
Gastric Cancer is one of the most common types of cancer. And the occurrence of gastric carcinoma is an evolutionary histopathological stage. As a result, further research of GPL, which is a borderline of gastric cancer, is indispensable for preventing the formation and development of gastric carcinoma. Several studies have demonstrated a correlation between the expression of autophagy, apoptosis and Gastric cancer (GC). However, the effects of autophagy and apoptosis on human gastric cancer progression, particularly on gastric precancerous lesions (GPL), have not totally been investigated...
May 15, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29772779/sober-mcs-sociability-oriented-and-battery-efficient-recruitment-for-mobile-crowd-sensing
#12
Fazel Anjomshoa, Burak Kantarci
The Internet of Things (IoT) concept is aiming at being an integral part of the next generation networking services by introducing pervasiveness and ubiquitous interconnectivity of uniquely-identifiable objects. The massive availability of personalized smart devices such as smartphones and wearables enable their penetration into the IoT ecosystem with their built-in sensors, particularly in Mobile Crowd-Sensing (MCS) campaigns. The MCS systems achieve the objectives of the large-scale non-dedicated sensing concept in the IoT if a sufficient number of participants are engaged to the collaborative data acquisition process...
May 17, 2018: Sensors
https://www.readbyqxmd.com/read/29769363/local-interactions-underlying-collective-motion-in-human-crowds
#13
Kevin W Rio, Gregory C Dachner, William H Warren
It is commonly believed that global patterns of motion in flocks, schools and crowds emerge from local interactions between individuals, through a process of self-organization. The key to explaining such collective behaviour thus lies in deciphering these local interactions. We take an experiment-driven approach to modelling collective motion in human crowds. Previously, we observed that a pedestrian aligns their velocity vector (speed and heading direction) with that of a neighbour. Here we investigate the neighbourhood of interaction in a crowd: which neighbours influence a pedestrian's behaviour, how this depends on neighbour position, and how the influences of multiple neighbours are combined...
May 16, 2018: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29767154/husbandry-practices-and-gut-health-outcomes-in-weaned-piglets-a-review
#14
REVIEW
Balachandar Jayaraman, Charles M Nyachoti
The immediate post-weaning period is one of the most stressful phases in a pig's life, and during this period, piglets are usually exposed to environmental, social and psychological stressors which have direct or indirect effects on gut health and overall growth performance. In this review, the impact of husbandry practices on gut health outcomes and performance of piglets is discussed. Husbandry practices in the swine barn generally include nutrition and management practices, maintenance of hygienic standards and disease prevention protocols, and animal welfare considerations...
September 2017: Animal nutrition
https://www.readbyqxmd.com/read/29765073/oncotically-driven-control-over-glycocalyx-dimension-for-cell-surface-engineering-and-protein-binding-in-the-longitudinal-direction
#15
Erika M J Siren, Rafi Chapanian, Iren Constantinescu, Donald E Brooks, Jayachandran N Kizhakkedathu
Here we present a simple technique for re-directing reactions on the cell surface to the outermost region of the glycocalyx. Macromolecular crowding with inert polymers was utilized to reversibly alter the accessibility of glycocalyx proteoglycans toward cell-surface reactive probes allowing for reactivity control in the longitudinal direction ('z'-direction) on the glycocalyx. Studies in HUVECs demonstrated an oncotically driven collapse of the glycocalyx brush structure in the presence of crowders as the mechanism responsible for re-directing reactivity...
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29765051/concurrent-and-orthogonal-gold-i-and-ruthenium-ii-catalysis-inside-living-cells
#16
Cristian Vidal, María Tomás-Gamasa, Paolo Destito, Fernando López, José L Mascareñas
The viability of building artificial metabolic pathways within a cell will depend on our ability to design biocompatible and orthogonal catalysts capable of achieving non-natural transformations. In this context, transition metal complexes offer unique possibilities to develop catalytic reactions that do not occur in nature. However, translating the potential of metal catalysts to living cells poses numerous challenges associated to their biocompatibility, and their stability and reactivity in crowded aqueous environments...
May 15, 2018: Nature Communications
https://www.readbyqxmd.com/read/29764795/mapping-of-crowdsourcing-in-health-systematic-review
#17
REVIEW
Perrine Créquit, Ghizlène Mansouri, Mehdi Benchoufi, Alexandre Vivot, Philippe Ravaud
BACKGROUND: Crowdsourcing involves obtaining ideas, needed services, or content by soliciting Web-based contributions from a crowd. The 4 types of crowdsourced tasks (problem solving, data processing, surveillance or monitoring, and surveying) can be applied in the 3 categories of health (promotion, research, and care). OBJECTIVE: This study aimed to map the different applications of crowdsourcing in health to assess the fields of health that are using crowdsourcing and the crowdsourced tasks used...
May 15, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29764678/re-engaging-with-places-understanding-bio-geo-graphical-disruption-and-flow-in-adult-brain-injury-survivors
#18
Louise Meijering, Nicky Theunissen, Ant T Lettinga
Acquired Brain Injury (ABI) is one of the most common causes of disability and death in adults worldwide. After a period of rehabilitation, many ABI survivors still face complex mind/body conditions when they try to take up their former life again. Besides lasting visible impairments such as weakness and loss of body balance, there are often less obvious disabilities such as extreme fatigue, hypersensitivity for stimuli, memory, concentration and attention problems or personality changes. The aim of this paper is to understand how ABI survivors and their significant others renegotiate their engagements with everyday places, using the concepts of bio-geo-graphical disruption and flow...
May 5, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29763700/grafting-polymerization-of-acrylic-acid-onto-chitosan-cellulose-hybrid-and-application-of-the-graft-as-highly-efficient-ligand-for-elimination-of-water-hardness-validation-of-high-selectivity-in-presence-of-interfering-ions
#19
Magdy F Mohamed, Xiaojian Zhou, Hanan S Ibrahim, Nabila S Ammar, Hisham A Essawy
Graft Copolymer resulting from polymerization of acrylic acid from chitosan is non-coherent, brittle and exhibit modest swelling in water, which limits its application. Chitosan-cellulose hybrid was initially prepared and novel polymeric ligand ((CTS/Cell)-g-PAA) derived from grafting polymerization of acrylic acid from this hybrid was fabricated and investigated using fourier transform infrared (FTIR) and Scanning electron microscopy (SEM). Also, the graft copolymer exhibited high mass transfer under a wide range of pH values due to its elevated hydrophilicity in addition to a good mechanical strength with respect to the comparable graft derived from chitosan as sole backbone for the grafting...
May 12, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29763547/tracer-transport-probes-relaxation-and-structure-of-attractive-and-repulsive-glassy-liquids
#20
Ryan C Roberts, Ryan Poling-Skutvik, Jeremy C Palmer, Jacinta C Conrad
Dynamic coupling of small penetrants to slow, cooperative relaxations within crowded cells, supercooled liquids, and polymer matrices has broad consequences for applications ranging from drug delivery to nanocomposite processing. Interactions between the constituents of these and other disordered media alter the cooperative relaxations, but their effect on penetrant dynamics remains incompletely understood. We use molecular dynamics simulations to show that the motions of hard-sphere tracer particles probe differences in local structure and cooperative relaxation processes in attractive and repulsive glassy liquid matrices with equal bulk packing fractions and long-time diffusivities...
May 15, 2018: Journal of Physical Chemistry Letters
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