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https://www.readbyqxmd.com/read/28340393/when-public-health-intervention-is-not-successful-cost-sharing-crowd-out-and-selection-in-korea-s-national-cancer-screening-program
#1
Hyuncheol Bryant Kim, Sun-Mi Lee
This study investigates the impact of and behavioral responses to cost sharing in Korea's National Cancer Screening Program, which provides free stomach and breast cancer screenings to those with an income below a certain cutoff. Free cancer screening substantially increases the screening take up rate, yielding more cancer detections. However, the increase in cancer detection is quickly crowded out by cancer detection through other channels such as diagnostic testing and private cancer screening. Further, compliers are much less likely to have cancer than never takers...
March 6, 2017: Journal of Health Economics
https://www.readbyqxmd.com/read/28338132/in-out-isomerism-of-cyclophanes-a-theoretical-account-of-2-6-15-trithia-3-4-10-7-metacyclophane-and-3-4-10-7-metacyclophane-as-well-as-their-halogen-substituted-analogues
#2
Milena Vujović, Matija Zlatar, Miloš Milčić, Maja Gruden
A detailed theoretical investigation of cyclophanes with a divergent set of methods ranging from molecular mechanics through semiempirical to ab initio is presented. Cyclophanes have attracted interest over the years due to their unusual chemistry and increasing applications. There has been previous debate over the effects contributing to the greater stability of more-crowded in isomers of certain cyclophanes, and a higher strain in the out isomer was the prevailing explanation. Application of EDA-NOCV and SAPT analysis has enabled us to distinguish between different effects controlling isomer stability and determine the significance of all effects involved...
March 24, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28337728/collinear-masking-effect-in-visual-search-is-independent-of-perceptual-salience
#3
Li Jingling, Yi-Hui Lu, Miao Cheng, Chia-Huei Tseng
Searching for a target in a salient region should be easier than looking for one in a nonsalient region. However, we previously discovered a contradictory phenomenon in which a local target in a salient structure was more difficult to find than one in the background. The salient structure was constructed of orientation singletons aligned to each other to form a collinear structure. In the present study, we undertake to determine whether such a masking effect was a result of salience competition between a global structure and the local target...
March 23, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/28337423/immediate-changes-in-the-mandibular-dentition-after-maxillary-molar-distalization-using-headgear
#4
Sung-Ja Kang, Hyun-Hee Kim, Hyeon-Shik Hwang, Kyung-Min Lee
The purpose of this study was to investigate immediate changes in the mandibular dentition after maxillary molar distalization using headgear in non-growing patients. Sixteen patients (mean age, 18.9 ± 2.0 years) with Class II molar relationship and crowding were included in the present study. To correct the molar relationship, headgear was used for maxillary molar distalization. Cone-beam computed tomography-generated half-cephalograms (CG Cephs) and dental casts were used to evaluate dental changes for each subject before and immediately after molar distalization using headgear...
March 2017: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/28337422/the-combined-use-of-computer-guided-minimally-invasive-flapless-corticotomy-and-clear-aligners-as-a-novel-approach-to-moderate-crowding-a-case-report
#5
Michele Cassetta, Federica Altieri, Stefano Pandolfi, Matteo Giansanti
The aim of this case report was to describe an innovative orthodontic treatment method that combined surgical and orthodontic techniques. The novel method was used to achieve a positive result in a case of moderate crowding by employing a computer-guided piezocision procedure followed by the use of clear aligners. A 23-year-old woman had a malocclusion with moderate crowding. Her periodontal indices, oral health-related quality of life (OHRQoL), and treatment time were evaluated. The treatment included interproximal corticotomy cuts extending through the entire thickness of the cortical layer, without a full-thickness flap reflection...
March 2017: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/28336938/a-pso-based-multi-objective-multi-label-feature-selection-method-in-classification
#6
Yong Zhang, Dun-Wei Gong, Xiao-Yan Sun, Yi-Nan Guo
Feature selection is an important data preprocessing technique in multi-label classification. Although a large number of studies have been proposed to tackle feature selection problem, there are a few cases for multi-label data. This paper studies a multi-label feature selection algorithm using an improved multi-objective particle swarm optimization (PSO), with the purpose of searching for a Pareto set of non-dominated solutions (feature subsets). Two new operators are employed to improve the performance of the proposed PSO-based algorithm...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28336796/the-ethics-of-data-and-of-data-science-an-economist-s-perspective
#7
REVIEW
Jonathan Cave
Data collection and modelling are increasingly important in social science and science-based policy, but threaten to crowd out other ways of thinking. Economists recognize that markets embody and shed light on human sentiments. However, their ethical consequences have been difficult to interpret, let alone manage. Although economic mechanisms are changed by data intensity, they can be redesigned to restore their benefits. We conclude with four cautions: if data are good, more may not be better; scientifically desirable data properties may not help policy; consent is a double-edged tool; and data exist only because someone thought to capture and codify them...
December 28, 2016: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28336382/migration-and-infectious-diseases
#8
REVIEW
Francesco Castelli, Giorgia Sulis
BACKGROUND: Infectious diseases still represent an important cause of morbidity and mortality among foreign-born individuals. The rising migration flows towards Europe throughout the last few years are raising renewed concerns about management issues and the potential associated risk for the native population. AIMS: To discuss the health implications and challenges related to the four phases of migration, from first arrival to stable resettlement. SOURCES: Scientific literature and relevant statistical reports...
March 20, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28335683/redescription-of-pallisentis-brevitritospinus-indica-acanthocephala-quadrigyridae-from-channa-punctatus-bloch-schneider-channidae-in-aligarh-india-with-new-understandings-of-old-structures
#9
Omar M Amin, Richard Heckmann, Ahammed Shareef
Pallisentis indica Mital and Lal, 1976 was originally described from Channa gatchua Hamilton (Channidae) in Kali nadi River, Aligarh, India. It was later placed in the subgenus Brevitritospinus Amin, Heckmann, Ha, Luc, and Doanh, 2000. Our collection from the spotted snakehead Channa punctatus Bloch & Schneider in another locality of the same stream in Aligarh produced many specimens with variable traits revealing new structures that have never before been described in the Acanthocephala, especially relating to the ducted trunk spines...
March 23, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28334556/impact-of-a-hospitalwide-quality-improvement-initiative-on-emergency-department-throughput-and-crowding-measures
#10
James D Melton, Fred Blind, A Brad Hall, Maureen Leckie, April Novotny
BACKGROUND: This pre- and postintervention analysis evaluates the impact of a systemwide, comprehensive, executively supported quality improvement (QI) project on emergency department (ED) throughput measures and crowding in a large nonacademic community hospital. METHODS: The two primary endpoints used to assess the impact of the project were (1) the percentage of all patients who were door-in to door-out in less than three hours and (2) the percentage of patients who left without being seen (LWBS)...
December 2016: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28331350/risk-factors-for-multidrug-resistant-tuberculosis-among-tuberculosis-patients-a-case-control-study
#11
Abdulhalik Workicho, Wondwosen Kassahun, Fessahaye Alemseged
BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) did not receive major attention until recently in sub-Saharan Africa where the tuberculosis incidence and risk factors are highest. Factors leading to development of drug resistance need to be understood to develop appropriate control strategies for national programs. The objective of this study was to identify the risk factors for MDR-TB among tuberculosis patients. METHODS: A case-control study was conducted to assess sociodemographic, behavioral and clinical risk factors using a structured questionnaire and clinical record reviewing...
2017: Infection and Drug Resistance
https://www.readbyqxmd.com/read/28328209/multidk-a-multiple-descriptor-multiple-kernel-approach-for-molecular-discovery-and-its-application-to-the-discovery-of-organic-flow-battery-electrolytes
#12
Sung-Jin Kim, Adrián Jinich, Alán Aspuru-Guzik
We propose a multiple descriptor multiple kernel (MultiDK) method for efficient molecular discovery using machine learning. We show that the MultiDK method improves both the speed and accuracy of molecular property prediction. We apply the method to the discovery of electrolyte molecules for aqueous redox flow batteries. Using \emph{multiple-type - as opposed to single-type - descriptors}, we obtain more relevant features for machine learning. Following the principle of 'wisdom of the crowds', the combination of multiple-type descriptors significantly boosts prediction performance...
March 22, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28328080/crowding-in-how-indian-civil-society-organizations-began-mobilizing-around-climate-change
#13
Tuomas Ylä-Anttila, Pradip Swarnakar
This paper argues that periodic waves of crowding-in to 'hot' issue fields are a recurring feature of how globally networked civil society organizations operate, especially in countries of the Global South. We elaborate on this argument through a study of Indian civil society mobilization around climate change. Five key mechanisms contribute to crowding-in processes: (1) the expansion of discursive opportunities; (2) the event effects of global climate change conferences; (3) the network effects created by expanding global civil society networks; (4) the adoption and innovation of action repertoires; and (5) global pressure effects creating new opportunities for civil society...
March 22, 2017: British Journal of Sociology
https://www.readbyqxmd.com/read/28327993/stepwise-distributed-open-innovation-contests-for-software-development-acceleration-of-genome-wide-association-analysis
#14
Andrew Hill, Po-Ru Loh, Ragu B Bharadwaj, Pascal Pons, Jingbo Shang, Eva Guinan, Karim Lakhani, Iain Kilty, Scott A Jelinsky
BACKGROUND: The association of differing genotypes with disease related phenotypic traits offers great potential to both help identify new therapeutic targets and support stratification of patients who would gain the greatest benefit from specific drug classes. Development of low cost genotyping and sequencing has made collecting large scale genotyping data routine in population and therapeutic intervention studies. In addition, a range of new technologies are being used to capture numerous new and complex phenotypic descriptors...
February 28, 2017: GigaScience
https://www.readbyqxmd.com/read/28327525/prevalence-of-malocclusion-in-3-to-5-year-old-children-in-shanghai-china
#15
Xinhua Zhou, Ying Zhang, Yan Wang, Hao Zhang, Li Chen, Yuehua Liu
The aim of the present study was to obtain the prevalence of malocclusions in preschool children in Shanghai, China. A cross-sectional survey was conducted among 2335 children aged 3-5 years from kindergartens. Several occlusal parameters were clinically assessed, including second deciduous molar terminal plane, canine relationship, degree of overjet and overbite, anterior and posterior crossbite, and the presence or absence of physiologic spaces and crowding. All parents of subjects were asked to fill in the oral health knowledge questionnaires...
March 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28320651/collaborative-active-visual-recognition-from-crowds-a-distributed-ensemble-approach
#16
Gang Hua, Chengjiang Long, Ming Yang, Yan Gao
Active learning is an effective way of engaging users to interactively train models for visual recognition more efficiently. The vast majority of previous works focused on active learning with a single human oracle. The problem of active learning with multiple oracles in a collaborative setting has not been well explored. We present a collaborative computational model for active learning with multiple human oracles, the input from whom may be subject to different levels of noise. It leads to not only an ensemble kernel machine that is robust to label noise, but also a principled label quality measure to online detect irresponsible labelers...
March 15, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28318260/correction-to-molecular-crowding-accelerates-ribozyme-docking-and-catalysis
#17
Bishnu P Paudel, David Rueda
No abstract text is available yet for this article.
March 20, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28316926/apert-syndrome-with-s252w-fgfr2-mutation-and-characterization-using-phenomizer-an-indian-case-report
#18
Fulesh Kunwar, Shikha Tewari, Sonal R Bakshi
Human genetic disease needs differential diagnosis to optimize clinical management, enable prenatal detection, and genetic counselling. The current methods of robust DNA sequencing also require next generation phenotyping to match with for better interpretation of genotypic and phenotypic heterogeneity commonly observed. We report use of human ontology based phenotypic characterization with Phenomizer that gives statistical score for possible diagnoses based on which, the gene mutation was studied. A case of craniosynostosis which refers to a group of syndromes characterized by a premature fusion of skull was studied...
January 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28314103/computational-study-of-the-forces-driving-aggregation-of-ultrasmall-nanoparticles-in-biological-fluids
#19
Sergio A Hassan
Nanoparticle (NP) aggregation can lead to prolonged retention in tissues or embolism, among other adverse effects. Successful use in biomedicine thus requires the capability to make NPs with limited aggregative potential. Rational design is presently a challenge due to incomplete knowledge of their interactions in biofluids. Recently, ultrasmall gold NPs passivated with endogenous antioxidant glutathione have shown promise for use in vivo. Computer simulations are here conducted to identify the forces underlying aggregation (or lack thereof) of these NPs in a cell culture...
March 21, 2017: ACS Nano
https://www.readbyqxmd.com/read/28314048/modeling-electrokinetics-in-ionic-liquids
#20
Chao Wang, Jie Bao, Wenxiao Pan, Xin Sun
Using direct numerical simulations, we provide a thorough study regarding the electrokinetics of ionic liquids. In particular, modified Poisson-Nernst-Planck (MPNP) equations are solved to capture the crowding and overscreening effects characteristic of an ionic liquid. For modeling electrokinetic flows in an ionic liquid, the MPNP equations are coupled with Navier-Stokes equations to study the coupling of ion transport, hydrodynamics, and electrostatic forces. Specifically, we consider the ion transport between two parallel charged surfaces, charging dynamics in a nanopore, capacitance of electric double-layer capacitors, electro-osmotic flow in a nanochannel, electroconvective instability on a plane ion-selective surface, and electroconvective flow on a curved ion-selective surface...
March 17, 2017: Electrophoresis
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