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Lower urinary tract symptom

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https://www.readbyqxmd.com/read/28803902/association-between-irritable-bowel-syndrome-and-overactive-bladder-a-research-survey
#1
Kyu Shik Kim, Hyung-Jee Kim, Seong Ho Lee, Sung Tae Cho, Hong Sang Moon
OBJECTIVE: To investigated the relationship between irritable bowel syndrome (IBS) and overactive bladder (OAB) in men and women using questionnaires. MATERIAL AND METHODS: This research survey was based on multi-center data (men and women older than 20 years). The Korean version of the Rome III criteria was used for the diagnosis of IBS, overactive bladder symptom score (OABSS) was used for screening OAB, Self-Rating Depression Scale (SDS) was used for depressive symptoms, and International Prostate Symptom Score & Quality of Life (IPSS & QoL) were used to determine the degrees of lower urinary tract symptoms...
August 10, 2017: Urology
https://www.readbyqxmd.com/read/28801563/the-global-burden-of-lower-urinary-tract-symptoms-suggestive-of-benign-prostatic-hyperplasia-a-systematic-review-and-meta-analysis
#2
Shaun Wen Huey Lee, Esther Mei Ching Chan, Yin Key Lai
Benign prostatic hyperplasia is a common non-malignant condition among older men, but the epidemiology is poorly characterised. We summarised and determined the global prevalence of benign prostatic hyperplasia. A systematic search on PubMed, EMBASE and CENTRAL was performed up until 31(st) July 2016. Studies that described the epidemiology of benign prostatic hyperplasia were included and cumulative plots of prevalence estimates were calculated. A total of 31 prevalence rate estimates from 25 countries were identified...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28801396/the-sims-trial-adjustable-anchored-single-incision-mini-slings-versus-standard-tension-free-midurethral-slings-in-the-surgical-management-of-female-stress-urinary-incontinence-a-study-protocol-for-a-pragmatic-multicentre-non-inferiority-randomised-controlled
#3
Mohamed Abdel-Fattah, Graeme MacLennan, Mary Kilonzo, R Phil Assassa, Kirsty McCormick, Tracey Davidson, Alison McDonald, James N'Dow, Judith Wardle, John Norrie
INTRODUCTION: Single-incision mini-slings (SIMS) represent the third generation of midurethral slings. They have been developed with the aim of offering a true ambulatory procedure for treatment of female stress urinary incontinence (SUI) with reduced morbidity and earlier recovery while maintaining similar efficacy to standard midurethral slings (SMUS). The aim of this study is to determine the clinical and cost-effectiveness of adjustable anchored SIMS compared with tension-free SMUS in the surgical management of female SUI, with 3-year follow-up...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28800482/targeting-phenotypic-heterogeneity-in-benign-prostatic-hyperplasia
#4
REVIEW
Douglas W Strand, Daniel N Costa, Franto Francis, William A Ricke, Claus G Roehrborn
Benign prostatic hyperplasia and associated lower urinary tract symptoms remain difficult to treat medically, resulting in hundreds of thousands of surgeries performed annually in elderly males. New therapies have not improved clinical outcomes since alpha blockers and 5 alpha reductase inhibitors were introduced in the 1990s. An underappreciated confounder to identifying novel targets is pathological heterogeneity. Individual patients display unique phenotypes, composed of distinct cell types. We have yet to develop a cellular or molecular understanding of these unique phenotypes, which has led to failure in developing targeted therapies for personalized medicine...
August 4, 2017: Differentiation; Research in Biological Diversity
https://www.readbyqxmd.com/read/28796057/risk-factors-for-bladder-calculi-in-patients-with-benign-prostatic-hyperplasia
#5
Wei Huang, Jun-Jie Cao, Min Cao, Hong-Shen Wu, Yong-Yi Yang, Zi-Meng Xu, Xiao-Dong Jin
We aim to find the risk factors that influence the formation of bladder calculi in patients with benign prostate hyperplasia (BPH) and to reduce the surgical intervention related to bladder calculi.Between January 2015 and October 2016, 332 patients with BPH underwent surgical therapy were retrospectively evaluated. Patients with BPH were categorized into 2 groups: 94 patients with bladder calculi in group 1 and 238 patients without bladder calculi in group 2. Medical history, age, body mass index (BMI), total prostate specific antigen, total prostate volume (TPV), International Prostate Symptom Score (IPSS), intravesical prostatic protrusion (IPP), urodynamic parameters, and urine culture were compared between groups...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28795417/molecular-pathogenesis-of-human-prostate-basal-cell-hyperplasia
#6
Gervaise Henry, Alicia Malewska, Ryan Mauck, Jeffrey Gahan, Ryan Hutchinson, Jose Torrealba, Franto Francis, Claus Roehrborn, Douglas Strand
BACKGROUND: Understanding the molecular pathogenesis of distinct phenotypes in human benign prostatic hyperplasia (BPH) is essential to improving therapeutic intervention. Current therapies target smooth muscle and luminal epithelia for relief of lower urinary tract symptoms (LUTS) due to BPH, but basal cell hyperplasia (BCH) remains untargeted. The incidence of has been reported at 8-10%, but a molecular and cellular characterization has not been performed on this phenotype. METHODS: Using freshly digested tissue from surgical specimens, we performed RNA-seq analysis of flow cytometry-purified basal epithelia from 3 patients with and 4 patients without a majority BCH phenotype...
August 10, 2017: Prostate
https://www.readbyqxmd.com/read/28794594/the-predictive-factors-of-%C3%AE-1-d-a-adrenoceptor-antagonist-naftopidil-dose-increase-therapy-for-male-lower-urinary-tract-symptoms-caused-by-benign-prostatic-hyperplasia-inform-study
#7
Yasushi Tanuma, Yoshinori Tanaka, Ko Takeyama, Tomoshi Okamoto
INTRODUCTION: We evaluated the predictive factors which affect the efficacy of naftopidil 50 mg/day therapy and dose increase therapy to administration of 75 mg/day after an initial dose of 50 mg/day. MATERIALS AND METHODS: A total of 92 patients with male lower urinary tract symptoms/benign prostatic hyperplasia were administrated naftopidil 50 mg/day for 4 weeks (50 mg therapy). At week 4, the patients were divided into an effective and an ineffective group (Group E and Group I, respectively)...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28794589/is-urodynamic-study-is-a-necessity-for-evaluation-of-lower-urinary-tract-symptoms-in-postmenopausal-female-patients-result-of-a-prospective-observational-study
#8
Sunirmal Choudhury, Susanta Kumar Das, Debarshi Jana, Dilip Kumar Pal
AIM: The aim of this study is to evaluate the causes of lower urinary tract symptoms (LUTS) in postmenopausal female patients (PMFP) and correlate their symptoms with their urodynamic study (UDS) findings. MATERIALS AND METHODS: A prospective observational study analyzing the clinical and UDS findings of PMFP presenting with LUTS. A detailed history including history of diabetes, neurological disease, drug history, and pelvic surgeries was taken, followed by physical examination and urodynamic assessment...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28792700/alternatively-activated-macrophages-are-associated-with-prostate-volume-and-lower-urinary-tract-symptoms-severity-of-patients-with-benign-prostate-hyperplasia
#9
Wenxue Hu, Wei Liu, Feng Yu, Yanhua Wu, Xiaowu Fang, Wenke Hao
BACKGROUND: Recent studies show that alternatively activated macrophages (AAMs) are involved in tissue remodeling and fibrosis. However, the relationship between AAMs and the development of benign prostate hyperplasia (BPH) is unclear. The aim of this study is to investigate the correlation among AAMs, prostate volume, and lower urinary tract symptoms (LUTS) severity of benign prostate hyperplasia (BPH) patients. METHODS: Patients who underwent transurethral incision of the prostate (TUIP) for BPH were recruited and international prostatic symptom scores (IPSS) were assessed before the operations...
July 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28791447/effect-of-pulsed-magnetic-stimulation-on-quality-of-life-of-female-patients-with-stress-urinary-incontinence-an-ideal-d-stage-2b-study
#10
Renly Lim, Men Long Liong, Wing Seng Leong, Nurzalina Abdul Karim Khan, Kah Hay Yuen
INTRODUCTION AND HYPOTHESIS: We evaluated the effects of pulsed magnetic stimulation (PMS) on overall and different aspects of quality of life (QoL) in female patients with stress urinary incontinence (SUI). METHODS: This study involved 120 female SUI subjects aged ≥21 years old randomized to either active or sham PMS. Treatment involved two PMS sessions per week for 2 months (16 sessions). After 2 months, subjects could opt for 16 additional sessions regardless of initial randomization...
August 8, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28791236/interstitial-cystitis-intravesical-therapy
#11
REVIEW
Tanya Ha, Jie Hua Xu
Interstitial cystitis (IC) is a progressive bladder disorder that presents with symptoms of bladder urgency, frequency and pain. The aetiology of the disease remains uncertain, but it is postulated that there is an initial infective insult which damages the glycosaminoglycan (GAG) layer of the bladder urothelium. This defect allows an influx of ions, particularly potassium, which initiates an inflammatory reaction in the bladder wall, which incites the symptoms described above. Treatment initially involves behavioural and oral medication, with second line being intravesical instillation therapy...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28791232/optimising-patient-outcomes-with-photoselective-vaporization-of-the-prostate-pvp-a-review
#12
REVIEW
Claire Pascoe, Darren Ow, Marlon Perera, Henry H Woo, Greg Jack, Nathan Lawrentschuk
Benign prostatic hyperplasia (BPH) is a common pathology causing lower urinary tract symptoms (LUTS) and may significantly impact quality of life. While transurethral resection of the prostate (TURP) remains the gold standard treatment, there are many evolving technologies that are gaining popularity. Photoselective vaporization of the prostate (PVP) is one such therapy which has been shown to be non-inferior to TURP. We aimed to review the literature and discuss factors to optimise patient outcomes in the setting of PVP for BPH...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28791231/medium-term-efficacy-of-the-prostatic-urethral-lift
#13
REVIEW
Peter Chin, Peter Robertson
Treatment options for patients with benign prostatic hyperplasia have traditionally revolved around pharmacotherapy or invasive surgery, both of which can negatively impact quality of life (QoL). The quest for a suitable minimally invasive surgical therapy as an alternative to long-term medication or conventional surgery, has seen the development of heat-based therapies, most of which have been dismissed because of post-operative complications and unacceptable re-treatment rates. During the late 1980s and 1990s, mechanical approaches such as transurethral balloon dilation and prostatic urethral stenting were investigated; however, re-treatment rates, encrustation and unacceptable migration rate of stents saw these options fall into disuse...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28791225/surgical-management-of-female-urethral-strictures
#14
REVIEW
Nathan Hoag, Justin Chee
Female urethral stricture (FUS) represents a rare condition, yet one that can cause significant, bothersome lower urinary tract symptoms (LUTS). Historically, urethral dilation has been a preferred treatment choice for these patients. A variety of reconstructive surgical techniques have been described in recent years to provide more definitive management in this challenging group of patients. We present an overview of FUS and a summary of surgical management options.
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28791223/overactive-pelvic-floor-muscles-opfm-improving-diagnostic-accuracy-with-clinical-examination-and-functional-studies
#15
Hau Choong Aw, Weranja Ranasinghe, Philip Huang Min Tan, Helen E O'Connell
BACKGROUND: To identify the functional correlation of overactive pelvic floor muscles (OPFM) with cystoscopic and fluoroscopic urodynamic studies (FUDS), including urethral pressure measurements. METHODS: Patients refractory to conservative therapy including bladder retraining, medications and pelvic muscle exercises for a variety of gamut of storage and voiding disorders were evaluated. Prospective data for 201 patients across both genders who underwent flexible cystoscopy and urodynamics for lower urinary tract symptoms (LUTS) refractory to conservative management between 01 Jan 2014 and 01 Jan 2016 was collected...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28789796/the-bidirectional-relationship-between-anxiety-depression-and-lower-urinary-track-symptoms-a-nationwide-population-based-cohort-study
#16
Charles Lung-Cheng Huang, Ming-Ping Wu, Chung-Han Ho, Jhi-Joung Wang
BACKGROUND: Evidence has shown a positive correlation between lower urinary tract symptoms (LUTS) and anxiety/depression, but the direction and strength of the association are still unclear. We aimed to test the bidirectional association between LUTS and anxiety/depression using a longitudinal population database. METHODS: Using claims data obtained from the Taiwan National Health Insurance Research Database, 17,489 patients with LUTS and 34,978 non-LUTS matched controls (cohort 1); and 45,707 patients with anxiety, 19,306 patients with depression, 91,414 non-anxiety, and 38,720 non-depression matched controls (cohort 2) were enrolled between 1999 and 2008...
September 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28782261/minimally-invasive-measurement-of-vesical-pressure-for-diagnosis-of-infravesical-obstruction
#17
João C M de Almeida, Carlos A L D'Ancona, José W M Bassani
AIMS: This study was focused on the clinical test of an improved and portable version of a previously described urethral connector (UC), designed for minimally invasive measurement of vesical pressure and diagnosis of infravesical obstruction in men. METHODS: The conventional pressure-flow study (PFS) and the test with the new version of UC were applied to individuals reporting lower urinary tract symptoms (LUTS), who were then classified as obstructed or non-obstructed/equivocal based on the bladder outlet obstruction index (BOOI) from PFS data...
August 7, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28780635/convective-radiofrequency-water-vapor-thermal-therapy-with-rez%C3%A5-m-system
#18
REVIEW
Sevann Helo, Bradley Holland, Kevin T McVary
PURPOSE: Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) are amongst the most commonly treated conditions by urologists. Minimally invasive therapies for the treatment of BPH/LUTS have garnered increased interest as new technology has emerged, improving durability, efficacy, and safety. This paper reviews the most recent literature regarding water vapor therapy, a convective thermal therapy that ablates prostatic tissue. RECENT FINDINGS: The current literature includes a pilot study of 65 men and a randomized controlled trial (RCT) of 197 men investigating the efficacy and safety profile of water vapor therapy up to 2 years...
October 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28780634/holmium-laser-enucleation-of-the-prostate-in-patients-requiring-anticoagulation
#19
REVIEW
Marcelino Rivera, Amy Krambeck, James Lingeman
PURPOSE OF REVIEW: This is to evaluate and discuss the literature surrounding holmium laser enucleation of the prostate (HoLEP) in patients on anticoagulation. RECENT FINDINGS: The relationship of benign prostatic hyperplasia (BPH) to bothersome lower urinary tract symptoms (LUTS) is well established with a majority of men over the age of 60 having significant symptoms. Patients with severe enough symptoms often require surgery and with cardiovascular disease ranking as the primary cause of death in the USA, a growing number will be taking antiplatelet (AP) or anticoagulation (AC) for primary or secondary prevention of disease...
October 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28777927/carbohydrate-and-protein-intake-during-exertional-heat-stress-ameliorates-intestinal-epithelial-injury-and-small-intestine-permeability
#20
Rhiannon M J Snipe, Anthony Khoo, Cecilia M Kitic, Peter Gibson, Ricardo J S Costa
BACKGROUND: Exertional-heat stress (EHS) disturbs the integrity of the gastrointestinal tract leading to endotoxaemia and cytokinaemia, which have symptomatic and health implications. This study aimed to determine the effects of carbohydrate and protein intake during EHS on gastrointestinal integrity, symptoms and systemic responses. METHODS: Eleven (male n=6, female n=5) endurance runners completed 2h running at 60% V̇O2max in 35°C ambient temperature on three occasions in randomised order, consuming water (WATER) or 15g glucose (GLUC) or energy-matched whey protein hydrolysate (WPH) before and every 20min during EHS...
August 4, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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