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M T Georgescu, R Anghel
Rationale: brachytherapy is administered in the treatment of patients with locally advanced cervical cancer following chemoradiotherapy. Lack of local anatomy evaluation prior to this procedure might lead to the selection of an inappropriate brachytherapy applicator, increasing the risk of side effects (e.g. uterus perforation, painful procedure ...). Objective: To assess the movement of the uterus and cervix prior to brachytherapy in patients with gynecological cancer, in order to select the proper type of brachytherapy applicator...
January 2017: Journal of Medicine and Life
Gabriella Cattari, Elena Delmastro, Sara Bresciani, Sergio Gribaudo, Antonella Melano, Flavio Giannelli, Maria Tessa, Renato Chiarlone, Tindaro Scolaro, Marco Krengli, Alessandro Urgesi, Pietro Gabriele
PURPOSE: We focused the attention on radiation therapy practices about the gynecological malignancies in Piedmont, Liguria, and Valle d'Aosta to know the current treatment practice and to improve the quality of care. MATERIAL AND METHODS: We proposed a cognitive survey to evaluate the standard practice patterns for gynecological cancer management, adopted from 2012 to 2014 by radiotherapy (RT) centers with a large amount of gynecological cancer cases. There were three topics: 1...
April 2016: Journal of Contemporary Brachytherapy
Xin Cai, Zhen Zhang
Considered that most of the phase II or III clinical trials contain less elderly patients or only contain those who had good health status, these results might not be applied in those elderly patients with some complex status. The patients of 70 years old or more usually have complications or worse organ function, thus the standard treatment for them becomes a gray zone. In rectal cancer patients, the rate of elderly patients receiving standard chemoradiotherapy (CRT) is obviously lower than that of the younger ones...
May 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
M Grimm, F Wenz
BACKGROUND: Radiation therapy is an established cornerstone in the treatment of prostate cancer. Significant advances in the techniques and therapeutic concepts have been made in recent decades. OBJECTIVES: The objective of this article is to provide an overview of current standards of care and recent technical and conceptional developments. CONCLUSIONS: Three-dimensional conformal radiotherapy has long been the standard of care for percutaneous radiotherapy...
March 2016: Der Urologe. Ausg. A
Barbara Röper, Christine Heinrich, Victoria Kehl, Hans Rechl, Katja Specht, Klaus Wörtler, Andreas Töpfer, Michael Molls, Severin Kampfer, Rüdiger von Eisenharth-Rothe, Stephanie E Combs
BACKGROUND: The aim of the trial is to demonstrate that with the use of modern IMRT/IGRT and reduction of safety margins postoperative wound complications can be reduced. METHODS/ DESIGN: The trial is designed as a prospective, monocentric clinical phase II trial. The treatment is performed with helical IMRT on the Tomotherapy HiArt System© or with RapidArc© IMRT as available. All treatments are performed with 6 MV photons and daily online CT-based IGRT. A dose of 50 Gy in 2 Gy single fractions (5 fractions per week) is prescribed...
November 16, 2015: BMC Cancer
Jamema V Swamidas, Christian Kirisits
No abstract text is available yet for this article.
January 2015: Journal of Medical Physics
Csaba Polgár, Tibor Major, Réka Király, János Fodor, Miklós Kásler
The purpose of the study is to report the status of Hungarian radiotherapy (RT) based on the assessment of treatment data in years 2012 to 2014, available infrastructure, and RT staffing. Between December 2014 and January 2015, a RT questionnaire including 3 parts (1. treatment data; 2. infrastructure; 3. staffing) was sent out to all Hungarian RT centers (n=12). All RT centers responded to all questions of the survey. 1. Treatment data: In 2014, 33,162 patients were treated with RT: 31,678 (95.5%) with teletherapy, and 1484 (4...
June 2015: Magyar Onkologia
Sreekanth Palvai, Michael Harrison, Sharon Shibu Thomas, Karen Hayden, James Green, Oliver Anderson, Lavinia Romero, Richard Lodge, Patricia Burns, Imtiaz Ahmed
BACKGROUND: Prostate cancer is the most common cancer in males in the UK and affects around 105 men for every 100,000. The role of radiotherapy in the management of prostate cancer significantly changed over the last few decades with developments in brachytherapy, external beam radiotherapy (EBRT), intensity-modulated radiotherapy (IMRT), and image-guided radiotherapy (IGRT). One of the challenging factors of radiotherapy treatment of localized prostate cancer is the development of acute and late genitourinary and gastrointestinal toxicities...
2015: JMIR Research Protocols
M Khadige, D Peiffert, S Supiot
Prostate cancer radiotherapy has evolved from the old 2D technique to conformal, and then to intensity-modulated radiation therapy (IMRT) and stereotactic radiotherapy. At the same time, image-guidance (IGRT) is routinely used. New techniques such as protontherapy or carbontherapy are being developed with the objective of increased efficacy, decreased treatment duration, toxicity or cost. This review summarizes the evidence-based medicine of new technologies in the treatment of prostate cancer.
October 2014: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
J López Torrecilla, A Zapatero, I Herruzo, F A Calvo, M A Cabeza, A Palacios, A Guerrero, A Hervás, P Lara, B Ludeña Martínez, E Del Cerro Peñalver, G Nagore, G Sancho, J L Mengual, M Mira, A Mairiño, P Samper, S Pérez, I Castillo, J C Martínez Cedrés, E Ferrer, S Rodriguez, X Maldonado, A Gómez Caamaño, C Ferrer
AIM: The purpose of the study was to describe infrastructures, treatment modalities, and workload in radiation oncology (RO) in Spain, referred particularly to prostate cancer (PC). METHODS: An epidemiologic, cross-sectional study was performed during 2008-2009. A study-specific questionnaire was sent to the 108 RO-registered departments. RESULTS: One hundred and two departments answered the survey, and six were contacted by telephone. Centers operated 236 treatment units: 23 (9...
May 2014: Clinical & Translational Oncology
Giovanna Mantini, Anna Rita Alitto, Bruno Fionda, Vincenzo Frascino, Gian Carlo Mattiucci, Mario Balducci, Alessio Giuseppe Morganti, Vincenzo Valentini
Prostate cancer is a heterogeneous, indolent or sometimes aggressive tumor. Treatment options are various and without proved superiority. Radiotherapy (RT) plays a key role in the disease history. Technological evolution with Intensity Modulate Radiation Therapy (IMRT) and Image Guided Radiation Therapy (IGRT) allowed improvement, with significant results on local control and survival. Hypofractionation, Stereotactic Body RT (SBRT) and new brachytherapy approachs are still under investigation, with promising opportunities...
July 2013: Urologia
Nicholas G Zaorsky, Amy S Harrison, Edouard J Trabulsi, Leonard G Gomella, Timothy N Showalter, Mark D Hurwitz, Adam P Dicker, Robert B Den
Conventional treatment options for clinically localized, low-risk prostate cancer include radical prostatectomy, external-beam radiotherapy (EBRT) and low-dose-rate brachytherapy. Advances in image-guided radiotherapy (IGRT) since the 1980s, the development of intensity-modulated radiotherapy (IMRT) during the 1990s and evidence from radiobiological models--which support the use of high doses per fraction--have developed alongside novel advanced radiotherapy modalities that include high-dose-rate brachytherapy (HDR-BT), stereotactic body radiotherapy (SBRT) and proton beam therapy...
October 2013: Nature Reviews. Urology
Carmen Bergom, Phillip Prior, Kristofer Kainz, Natalya V Morrow, Ergun E Ahunbay, Alonzo Walker, X Allen Li, Julia White
BACKGROUND AND PURPOSE: External beam accelerated partial breast irradiation (EB-aPBI) is noninvasive with broader potential applicability than aPBI using brachytherapy. However, it has inherent challenges in daily reproducibility. Image-guide radiotherapy (IGRT) can improve daily reproducibility, allowing smaller treatment margins. Our institution proposed IG-IMRT in the prone position to evaluate dose homogeneity, conformality, normal tissue avoidance, and reliable targeting for EB-aPBI...
August 2013: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
N Willich
Technical and methodical developments have changed radiation oncology substantially over the last 40 years. Modern imaging methods, e.g., computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and ultrasound (US), have not only improved the detection of tumors but have also become tools for computed treatment planning. Megavoltage irradiation with accelerators using photons and electrons with large and small fields, intensity modulation (IMRT), image-guided radiotherapy (IGRT), stereotactic irradiation and radiosurgery, intraoperative radiotherapy (IORT), and modern remote controlled afterloading brachytherapy have made high precision radiotherapy increasingly possible...
November 2012: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
T Kron, Ky Cheung, J Dai, P Ravindran, D Soejoko, K Inamura, Jy Song, L Bold, R Srivastava, L Rodriguez, Tj Wong, A Kumara, Cc Lee, A Krisanachinda, Xc Nguyen, Kh Ng
Medical physics plays an essential role in modern medicine. This is particularly evident in cancer care where medical physicists are involved in radiotherapy treatment planning and quality assurance as well as in imaging and radiation protection. Due to the large variety of tasks and interests, medical physics is often subdivided into specialties such as radiology, nuclear medicine and radiation oncology medical physics. However, even within their specialty, the role of radiation oncology medical physicists (ROMPs) is diverse and varies between different societies...
July 2008: Biomedical Imaging and Intervention Journal
Francesc Casas, Josep María Borràs, Ferran Ferrer, Núria Guanyabens, Rafael Gutiérrez del Pozo, Concha León, José López Torrecilla, Begoña Mellado, Joan Morote, Manel Puig, María José Ribal, Carme Ruscalleda, Agustí Serra, Valentí Valls, Almudena Zapatero
INTRODUCTION: Prostate cancer (PC) is one of the tumours with the highest incidence in recent years. PC therapies have several adverse effects. A panel consensus recommendation has been made to prevent or ameliorate complications in PC treatment to improve quality of life. MATERIAL AND METHODS: Fifteen specialists have met to analyse the different toxicities associated with PC treatment. Each medical specialist performed a National Library of Medicine PubMed search citations searching about these secondary effects and his specialty from 1999 to 2009 to propose measures for their prevention/amelioration...
May 2010: Clinical & Translational Oncology
Eric E Klein
Justification of clinical physics staffing levels is difficult due to the lack of direction as how to equate clinical needs with the staffing levels and competency required. When a physicist negotiates staffing requests to administration, she/he often refers to American College of Radiology staffing level suggestions, and resources such as the Abt studies. This approach is often met with questions as to how to fairly derive the time it takes to perform tasks. The result is often insufficient and/or inexperienced staff handling complex and cumbersome tasks...
December 3, 2009: Journal of Applied Clinical Medical Physics
Bin S Teh, Arnold Paulino, E Brian Butler
Significant developments in radiation oncology have taken place in recent years as a result of advances in radiation physics and molecular radiobiology. From the conventional 2-dimensional (2D) radiotherapy to 3-dimensional (3D) conformal radiotherapy, we have now entered the era of intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT). IMRT/IGRT allows conformal treatment of tumor and conformal avoidance of normal tissues leading to possible improvement of tumor control and decrease in treatment-related toxicity...
August 2008: Ai Zheng, Aizheng, Chinese Journal of Cancer
U Ganswindt, C Belka
Radiotherapy is a well-accepted treatment modality for patients with localised prostate cancer. Provided that radiotherapy is applied with a sufficient radiation dose, it is as effective as radical prostatectomy. Different radiation modalities are available (interstitial brachytherapy, external beam radiotherapy or a combination of both). Various new developments will further increase the value of radiation-based approaches. In this regard, a wider use of intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) will result in higher treatment doses with even lower toxicity rates...
September 2008: Der Urologe. Ausg. A
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