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https://www.readbyqxmd.com/read/27898751/-investigating-the-predictive-value-of-rmi-and-roma-indices-in-patients-with-ovarian-tumors-of-uncertain-dignity
#1
Géza Krascsenits, Boglárka Balázs, Anna Dudnyikova, Katalin Purcsi, Enikõ Orosz, Imre Pete
We were investigating the predictive value of RMI and ROMA indices in patients with ovarian tumors of uncertain dignity, in order to determine whether these methods are suitable for the early detection of ovarian malignancy. Our study included 162 patients treated at the Gynecological Department of the National Institute of Oncology (Budapest, Hungary). These patients were diagnosed with ovarian tumor of uncertain dignity, and were admitted to our Department with the purpose of gynecological surgery. Each of them had CA-125, HE4 blood tests and ultrasound scan in order to calculate RMI and ROMA indices and to study their effectiveness...
November 29, 2016: Magyar Onkologia
https://www.readbyqxmd.com/read/27885864/probabilistic-treatment-planning-for-pancreatic-cancer-treatment-prospective-incorporation-of-respiratory-motion-shows-only-limited-dosimetric-benefit
#2
Eelco Lens, Alexis N T J Kotte, Ajay Patel, Hanne D Heerkens, Matthieu Bal, Geertjan van Tienhoven, Arjan Bel, Astrid van der Horst, Gert J Meijer
BACKGROUND: We introduced a probabilistic treatment planning approach that prospectively incorporates respiratory-induced motion in the treatment plan optimization. The aim of this study was to determine the potential dosimetric benefit by comparing this approach to the use of an internal target volume (ITV). MATERIAL AND METHOD: We retrospectively compared the probabilistic respiratory motion-incorporated (RMI) approach to the ITV approach for 18 pancreatic cancer patients, for seven simulated respiratory amplitudes from 5 to 50 mm in the superior-inferior (SI) direction...
November 25, 2016: Acta Oncologica
https://www.readbyqxmd.com/read/27852697/chromosomal-instability-in-cell-free-dna-as-a-highly-specific-biomarker-for-detection-of-ovarian-cancer-in-women-with-adnexal-masses
#3
Adriaan Vanderstichele, Pieter Busschaert, Dominiek Smeets, Chiara Landolfo, Els Van Nieuwenhuysen, Karin Leunen, Patrick Neven, Frederic Amant, Sven Mahner, Elena Ioana Braicu, Robert Zeilinger, An Coosemans, Dirk Timmerman, Diether Lambrechts, Ignace Vergote
PURPOSE: Chromosomal instability is a hallmark of ovarian cancer. Here, we explore copy number alteration (CNA) profiling in cell-free DNA as a potential biomarker to detect malignancy in patients presenting with an adnexal mass. EXPERIMENTAL DESIGN: We prospectively enrolled 68 patients with an adnexal mass, of which 57 were diagnosed with invasive or borderline carcinoma and 11 with benign disease. Cell-free DNA was extracted from plasma and analyzed by low-coverage whole-genome sequencing...
November 14, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/27821988/ovarian-fibroma-a-clinico-pathological-study-of-23-cases-with-review-of-literature
#4
Nikhil Sadanand Parwate, Shilpa M Patel, Ruchi Arora, Monisha Gupta
PURPOSE: The purpose of this study was to correlate the clinical findings, RMI-4 index and frozen section, in cases of ovarian fibroma with the final histopathology. METHODS: This is a retrospective study of clinical and pathological features of 23 patients of ovarian fibroma. The patient's age ranged from 34 to 66 years (mean-49 years). The most common presenting symptom was abdominal pain. On clinical examination, the mean size of ovarian tumor was 9.5 cm, CA-125 levels were found to be raised in 14 patients, and it was associated with ascites in 10 patients...
December 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27815727/initial-experiments-with-gel-water-towards-mri-linac-dosimetry-and-imaging
#5
Sarah J Alnaghy, Maegan Gargett, Gary Liney, Marco Petasecca, Jarrad Begg, Anthony Espinoza, Matthew K Newall, Mitchell Duncan, Lois Holloway, Michael L F Lerch, Mircea Lazea, Anatoly B Rosenfeld, Peter Metcalfe
Tracking the position of a moving radiation detector in time and space during data acquisition can replicate 4D image-guided radiotherapy (4DIGRT). Magnetic resonance imaging (MRI)-linacs need MRI-visible detectors to achieve this, however, imaging solid phantoms is an issue. Hence, gel-water, a material that provides signal for MRI-visibility, and which will in future work, replace solid water for an MRI-linac 4DIGRT quality assurance tool, is discussed. MR and CT images of gel-water were acquired for visualisation and electron density verification...
November 4, 2016: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/27744465/assessment-of-demographic-and-clinical-characteristics-on-functional-status-and-disability-of-patients-with-stroke
#6
Derya Memis, Erkan Kozanoglu, Bayram Kelle, Mustafa K Goncu
OBJECTIVE: To determine the effects of demographic and clinical characteristics on mobility, disability, and activities of daily life of patients with stroke. METHODS: This cross-sectional clinical study was performed in the Department of Physical Medicine and Rehabilitation in Cukurova University Faculty of Medicine in Adana, Turkey, between February 2011 and December 2011. The study included 126 patients with stroke. The Brunnstrom recovery scale (BRS), functional ambulation classification scale (FACS), modified Barthel index (MBI), modified Rankin scale (MRS), and Rivermead mobility index (RMI) were used in the evaluation of the functional status of stroke patients...
October 2016: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/27740943/theoretical-and-experimental-characterization-of-novel-water-equivalent-plastics-in-clinical-high-energy-carbon-ion-beams
#7
A Lourenço, N Wellock, R Thomas, M Homer, H Bouchard, T Kanai, N MacDougall, G Royle, H Palmans
Water-equivalent plastics are frequently used in dosimetry for experimental simplicity. This work evaluates the water-equivalence of novel water-equivalent plastics specifically designed for light-ion beams, as well as commercially available plastics in a clinical high-energy carbon-ion beam. A plastic- to-water conversion factor [Formula: see text] was established to derive absorbed dose to water in a water phantom from ionization chamber readings performed in a plastic phantom. Three trial plastic materials with varying atomic compositions were produced and experimentally characterized in a high-energy carbon-ion beam...
October 14, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27730234/europium-metal-organic-frameworks-as-recyclable-and-selective-turn-off-fluorescent-sensors-for-aniline-detection
#8
Hui-Jun Feng, Ling Xu, Bing Liu, Huan Jiao
Seven Eu-(H)BDC compounds, [RMI][Eu2(BDC)3Cl] (R = ethyl (1), propyl (2), butyl (3), H2BDC = 1,4-benzenedicarboxylic acid), [EMI]2[Eu2(BDC)3(H2BDC)Cl2] (4), [Eu(BDC)(HCOO)] (5), [Eu(BDC)Cl(H2O)] (6) and [Eu3(BDC)4Cl(H2O)6] (7), were synthesized under ionothermal conditions. Compounds 4 and 6 behave as potential highly selective turn-off fluorescent sensors for aniline, which can be detected in mixtures of aniline with contrast organic amides or alkylbenzenes. Fluorescence quenching can be observed when compounds 4 and 6 mix with the samples containing aniline...
October 12, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27682511/egs_cbct-simulation-of-a-fan-beam-ct-and-rmi-phantom-for-measured-hu-verification
#9
Dete van Eeden, Freek du Plessis
INTRODUCTION: A mathematical 3D model of an existing computed tomography (CT) scanner was created and used in the EGSnrc-based BEAMnrc and egs_cbct Monte Carlo codes. Simulated transmission dose profiles of a RMI-465 phantom were analysed to verify Hounsfield numbers against measured data obtained from the CT scanner. METHODS AND MATERIALS: The modelled CT unit is based on the design of a Toshiba Aquilion 16 LB CT scanner. As a first step, BEAMnrc simulated the X-ray tube, filters, and secondary collimation to obtain phase space data of the X-ray beam...
September 24, 2016: Physica Medica: PM
https://www.readbyqxmd.com/read/27631218/prevalence-of-obesity-and-acanthosis-nigricans-among-young-children-in-the-children-s-healthy-living-program-in-the-united-states-affiliated-pacific
#10
Rachel Novotny, Fenfang Li, Marie Kainoa Fialkowski, Andrea Bersamin, Aifili Tufa, Jonathan Deenik, Patricia Coleman, Rachael Leon Guerrero, Lynne R Wilkens
Estimate prevalence of obesity and acanthosis nigricans (AN) among children in United States Affiliated Pacific (USAP) jurisdictions.Cross-sectional measurement of weight, height, and AN in 5775, 2 to 8 years old in 51 communities-Hawai'i, Alaska, Commonwealth of the Northern Mariana Islands, Guam, American Samoa, Palau, Republic of the Marshall Islands (RMI), 4 Federated States of Micronesia (Pohnpei, Yap, Kosrae, Chuuk). Analyses weighted to jurisdiction-specific sex and age distributions accounting for clustering of communities within jurisdictions...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27602187/evaluation-of-he4-ca-125-risk-of-ovarian-malignancy-algorithm-roma-and-risk-of-malignancy-index-rmi-in-the-preoperative-assessment-of-patients-with-adnexal-mass
#11
Khawla Al Musalhi, Manal Al Kindi, Faiza Al Aisary, Fatma Ramadhan, Thuraya Al Rawahi, Khalsa Al Hatali, Waad-Allah Mula-Abed
OBJECTIVES: To evaluate the validity and compare the performance of cancer antigen-125 (CA-125), human epididymis protein 4 (HE4), the risk of malignancy index (RMI), and the risk of ovarian malignancy algorithm (ROMA) in the diagnosis of ovarian cancer in patients with ovarian lesions discovered during their preoperative work-up investigations. METHODS: This prospective, cross-sectional study looked at patients who attended the gynecology department at the Royal Hospital, Muscat, from 1 March 2014 to 30 April 2015, for the evaluation of an ovarian lesion...
September 2016: Oman Medical Journal
https://www.readbyqxmd.com/read/27560201/notes-from-the-field-cluster-of-tuberculosis-cases-among-marshallese-persons-residing-in-arkansas-2014-2015
#12
Laura Lester Rothfeldt, Naveen Patil, Dirk T Haselow, Sandy Hainline Williams, J Gary Wheeler, Leonard N Mukasa
During early September 2014, the Arkansas Department of Health identified an increased number of tuberculosis (TB) cases among a unique population in a well-circumscribed geographical area in northwest Arkansas. The Compact of Free Association Act of 1985 (Public Law 99-239, amended in 2003 by Public Law 108-188) established the Republic of the Marshall Islands (RMI) as an independent nation, and persons from the RMI can travel freely (with valid RMI passport) to and from the United States as nonimmigrants without visas (1)...
2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27514486/estimating-the-risk-of-malignancy-in-adnexal-masses-an-external-validation-of-the-adnex-model-and-comparison-with-other-frequently-used-ultrasound-methods
#13
E M J Meys, L S Jeelof, N M J Achten, B F M Slangen, S Lambrechts, R F P M Kruitwagen, T Van Gorp
OBJECTIVES: The aim of this study was to externally validate the performance of the Assessment of Different NEoplasias in the adneXa (ADNEX) model and compare this model with other frequently used and evaluated models in the differential diagnosis of an adnexal mass. METHODS: In this retrospective diagnostic accuracy study we assessed prospectively collected data from patients with adnexal pathology who underwent real-time transvaginal or transrectal ultrasound by a single expert ultrasonographer in a tertiary care hospital between July 2011 and July 2015...
August 12, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27504643/the-predictive-validity-of-the-two-tiered-violence-risk-estimates-scale-ttv-in-a-long-term-follow-up-of-violent-offenders
#14
Frances P Churcher, Jeremy F Mills, Adelle E Forth
Over the past few decades many structured risk appraisal measures have been created to respond to this need. The Two-Tiered Violence Risk Estimates Scale (TTV) is a measure designed to integrate both an actuarial estimate of violence risk with critical risk management indicators. The current study examined interrater reliability and the predictive validity of the TTV in a sample of violent offenders (n = 120) over an average follow-up period of 17.75 years. The TTV was retrospectively scored and compared with the Violence Risk Appraisal Guide (VRAG), the Statistical Information of Recidivism Scale-Revised (SIR-R1), and the Psychopathy Checklist-Revised (PCL-R)...
August 2016: Psychological Services
https://www.readbyqxmd.com/read/27442666/hypocretin-1-levels-in-the-cerebrospinal-fluid-of-patients-with-percheron-artery-infarction-with-or-without-midbrain-involvement-a-case-series
#15
Keisuke Suzuki, Tomoyuki Miyamoto, Masayuki Miyamoto, Hiroto Maeda, Kazuya Nokura, Jun Tohyama, Koichi Hirata, Tetsuo Shimizu, Takashi Kanbayashi
BACKGROUND: Bilateral paramedian thalamic infarctions (BPTIs) due to artery of Percheron occlusion are known to cause hypersomnia. However, the role of hypocretin-1, a wake-promoting peptide that is located at the lateral hypothalamus, in hypersomnia in these patients remains unclear. METHODS: To clarify the role of hypocretin-1 in hypersomnia in patients with BPTIs, hypocretin-1 levels in the cerebrospinal fluid (CSF) were measured in 6 patients with BPTIs: 2 with rostral midbrain involvement (BPT+RMI) and 4 without midbrain involvement (BPT-MI)...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27440164/soluble-hemojuvelin-in-transfused-and-untransfused-thalassaemic-subjects
#16
Elisa Ferro, Angela Di Pietro, Giuseppa Visalli, Basilia Piraino, Carmelo Salpietro, Maria Angela La Rosa
OBJECTIVE: The hemojuvelin-bone morphogenetic protein axis is the principal iron-dependent mechanism of hepcidin regulation. The determination of soluble hemojuvelin (sHJV) levels could allow for a better understanding of the pathophysiological mechanisms of hepcidin regulation in thalassaemia. METHOD: We have assessed sHJV in 45 transfused and 15 untransfused thalassaemic patients in comparison with 15 healthy subjects, evaluating its relationships with some parameters of iron overload, anaemia and erythropoiesis...
July 21, 2016: European Journal of Haematology
https://www.readbyqxmd.com/read/27435369/approaches-to-the-detection-of-ovarian-cancer
#17
Estrid Høgdall
BACKGROUND: Ovarian cancer (OC) represents the eighth most common cancer among women and the second most frequently diagnosed gynecological malignancy in the United States and Europe. Correct and fast referral of patients with OC is mandatory to ensure optimal treatment and to improve the prognosis of patients with OC. Approaches to detect OC may be based on a gynecological examination, an elevated serum CA125 level, a Risk of Malignancy Index (RMI) higher than 200, an elevated serum HE4 level, or other modalities such as Risk of Ovarian Malignancy Algorithm (ROMA), Risk of Ovarian Cancer Algorithm (ROCA), or Copenhagen Index (CPH-I)...
2016: Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum
https://www.readbyqxmd.com/read/27430315/long-term-prognosis-of-unrecognized-myocardial-infarction-detected-with-cardiovascular-magnetic-resonance-in-an-elderly-population
#18
Charlotte Ebeling Barbier, Raquel Themudo, Tomas Bjerner, Lars Johansson, Lars Lind, Håkan Ahlström
BACKGROUND: Individuals with unrecognized myocardial infarctions (UMIs) detected with cardiovascular magnetic resonance (CMR) constitute a recently defined group whose prognosis has not been fully evaluated. However, increasing evidence indicate that these individuals may be at considerable cardiovascular risk. The aim of the present study was to investigate the prognostic impact of CMR detected UMIs for major adverse cardiac events (MACE) in community living elderly individuals. METHODS: Late gadolinium enhancement CMR was performed in 248 randomly chosen 70-year-olds...
2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27420146/-headhache-secondary-to-intracranial-hypotension-in-a-lumbar-spinal-stenosis-surgery
#19
Begoña Hidalgo-Mendía, Marina Angulo-Taberno, Ricardo Jaroid-Audes, Carmen Untoria-Agustín, David Rivero-Zelada
Intracraneal hypotension headache is a well known syndrome in neurosurgery practice. In most cases cerebrospinal fluid leaks are caused by medical interventions, such as lumbar puncture, peridural anesthesia and surgical interventions on the spine. Clinical symptoms tipically show orthostatic headache that resolves in supine position, and other symptoms like neck tightness, vertigo and diplopia. RMI diagnostic confirms paquimeningeal enhancement and subdural hygromas. Conservative treatment usually includes bed resting, hydratation and administration of caffeine or glucocorticoids, resolving spontaneously in one to four months...
2016: Revista de la Facultad de Ciencias Médicas
https://www.readbyqxmd.com/read/27408896/validation-of-computed-tomography-based-attenuation-correction-of-deviation-between-theoretical-and-actual-values-in-four-computed-tomography-scanners
#20
Nobuhiro Yada, Hideo Onishi
OBJECTIVES: In this study, we aimed to validate the accuracy of computed tomography-based attenuation correction (CTAC), using the bilinear scaling method. METHODS: The measured attenuation coefficient (μm) was compared to the theoretical attenuation coefficient (μt), using four different CT scanners and an RMI 467 phantom. The effective energy of CT beam X-rays was calculated, using the aluminum half-value layer method and was used in conjunction with an attenuation coefficient map to convert the CT numbers to μm values for the photon energy of 140 keV...
2016: Asia Oceania Journal of Nuclear Medicine & Biology
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