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Dress syndrome

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https://www.readbyqxmd.com/read/29661742/overlap-between-dress-syndrome-and-exanthema-induced-by-sulfadiazine-in-a-patient-treated-with-sulfamethoxazole-utility-of-the-lymphocyte-transformation-test-for-identification-of-the-culprit-drug
#1
O P Monge-Ortega, R Cabañas, A Fiandor, J Domínguez-Ortega, M González-Muñoz, S Quirce, M Lluch-Bernal, T Bellón
No abstract text is available yet for this article.
April 2018: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29656292/c-reactive-protein-and-procalcitonin-in-case-reports-of-drug-reaction-with-eosinophilia-and-systemic-symptoms-dress-syndrome
#2
Simona T Hübner, Raffaela Bertoli, Alexandra E Rätz Bravo, Martina Schaueblin, Manuel Haschke, Kathrin Scherer, Alessandro Ceschi, Anne B Leuppi-Taegtmeyer
BACKGROUND: The spectrum of inflammatory marker response in DRESS (drug reaction with eosinophilia and systemic symptoms) syndrome has not been systematically characterized. METHODS: An epidemiological biomarker study of C-reactive protein (CRP) and procalcitonin (PCT) values in patients with DRESS syndrome reported at 2 regional pharmacovigilance centers in Switzerland or published in the medical literature 2008-2016 was performed. RESULTS: Ninety-four DRESS cases were studied...
April 13, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29651444/an-updated-review-of-the-molecular-mechanisms-in-drug-hypersensitivity
#3
REVIEW
Chun-Bing Chen, Riichiro Abe, Ren-You Pan, Chuang-Wei Wang, Shuen-Iu Hung, Yi-Giien Tsai, Wen-Hung Chung
Drug hypersensitivity may manifest ranging from milder skin reactions (e.g., maculopapular exanthema and urticaria) to severe systemic reactions, such as anaphylaxis, drug reactions with eosinophilia and systemic symptoms (DRESS)/drug-induced hypersensitivity syndrome (DIHS), or Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). Current pharmacogenomic studies have made important strides in the prevention of some drug hypersensitivity through the identification of relevant genetic variants, particularly for genes encoding drug-metabolizing enzymes and human leukocyte antigens (HLAs)...
2018: Journal of Immunology Research
https://www.readbyqxmd.com/read/29644252/strategies-for-successful-treatment-of-active-tuberculosis-in-the-setting-of-dress-on-ripe
#4
Quratulain Kizilbash, Adriana Vasquez, Barbara Seaworth
We describe 2 young, female patients who developed drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome while on treatment for pulmonary tuberculosis (TB). Active TB was treated successfully with second-line TB medications, including moxifloxacin, ethambutol, linezolid, and amikacin for 18 months.
April 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29627131/treatment-of-toxic-epidermal-necrolysis-by-a-multidisciplinary-team-a-review-of-literature-and-treatment-results
#5
Anthony Papp, Sheena Sikora, Morgan Evans, Diana Song, Mark Kirchhof, Monica Miliszewski, Jan Dutz
BACKGROUND: Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are mucocutaneous hypersensitivity reactions, usually to drugs or their metabolites. TEN is the most severe involving greater than 30% of the total body surface area (TBSA). Management of these patients usually benefits from a large multidisciplinary team for both wound and medical management. Treatment of these patients varies between centers and physicians and there is lack of a standardized treatment protocol in the medical literature...
April 4, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29621952/dolutegravir-as-a-trigger-for-dress-syndrome
#6
Charlotte Martin, Marie-Christine Payen, Stephane De Wit
Dolutegravir is an increasingly-used second-generation human immunodeficiency virus integrase strand transfer inhibitor. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome has been described in several patients treated with raltegravir but to our knowledge, there is no previous report of DRESS syndrome associated with dolutegravir.
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29610167/-hla-a-31-01-and-oxcarbazepine-induced-dress-in-a-patient-with-seizures-and-complete-dcx-deletion
#7
Hyun Kim, Laura Chadwick, Yasir Alzaidi, Jonathan Picker, Annapurna Poduri, Shannon Manzi
Oxcarbazepine is an antiepileptic drug (AED) commonly used as a first-line treatment option for focal epilepsy. Several AEDs, including carbamazepine, oxcarbazepine, and phenytoin are associated with various delayed-hypersensitivity reactions such as drug reaction with eosinophilia and systemic symptoms, Stevens-Johnson syndrome, or toxic epidermal necrolysis. The Food and Drug Administration-approved label for oxcarbazepine currently presents information regarding a pharmacogenomic association with the HLA antigen allele HLA-B*15:02 and hypersensitivity reactions in certain ancestry groups with a high incidence of this allele...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29607632/trichloroethylene-hypersensitivity-syndrome-should-be-considered-when-diagnosing-dress-syndrome
#8
Young Joong Kang, Jihye Lee, Jungho Ahn, Soonwoo Park, Mu Young Shin, Hye Won Lee
Trichloroethylene (TCE) is an organic solvent that is used for degreasing and removing impurities from metal parts. However, this solvent's characteristics and hypersensitivity can produce clinical patterns and laboratory data that mimic drug rash with eosinophilia and systemic symptoms (DRESS) syndrome. Thus, exposure confirmation is critical to making an accurate diagnosis. This is a case of TCE-induced hypersensitivity syndrome (TCE HS) in a 24-year-old Indonesian man who was working in an electro-plating business...
April 2, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29588957/dress-syndrome-a-case-of-cross-reactivity-with-lacosamide
#9
Man Kei Fong, Bun Sheng
A 42-year-old patient with epilepsy was admitted to the hospital for fever and generalized skin rash. He has known allergy to phenytoin. Valproate was started in 2012, but failed to control his seizure despite gradual increase in dosage. Phenobarbitone was added 16 days before admission and was stopped on admission. He was treated with beta-lactam antibiotics. The rash subsided gradually after the cessation of phenobarbitone. Lacosamide was subsequently added for seizure control. Unfortunately, he developed drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome soon after introduction of lacosamide that required the use of systemic steroid for acute hepatitis...
June 2017: Epilepsia Open
https://www.readbyqxmd.com/read/29574562/severe-cutaneous-adverse-drug-reactions-presentation-risk-factors-and-management
#10
REVIEW
S Shahzad Mustafa, David Ostrov, Daniel Yerly
PURPOSE OF STUDY: Immune-mediated adverse drug reactions occur commonly in clinical practice and include mild, self-limited cutaneous eruptions, IgE-mediated hypersensitivity, and severe cutaneous adverse drug reactions (SCAR). SCARs represent an uncommon but potentially life-threatening form of delayed T cell-mediated reaction. The spectrum of illness ranges from acute generalized exanthematous pustulosis (AGEP) to drug reaction with eosinophilia with systemic symptoms (DRESS), to the most severe form of illness, Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)...
March 24, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29574127/unusual-clinical-manifestation-of-laryngeal-edema-in-a-case-of-dress-syndrome
#11
Da Woon Sim, Young-Il Koh
No abstract text is available yet for this article.
March 21, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29568997/-severe-skin-reactions-due-to-new-medications
#12
REVIEW
M Mockenhaupt, M Paulmann
Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and a specific form of hypersensitivity syndrome which is nowadays called "drug reaction with eosinophilia and systemic symptoms" (DRESS) are severe, mainly drug-induced skin reactions. Whereas SJS/TEN is considered one reaction entity of different severity, DRESS has to be distinguished from SJS/TEN but also from other severe exanthems due to multiorgan involvement. Although SJS/TEN is generally referred to as drug reaction, in total only about three quarters of the cases are actually caused by drugs...
April 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29567083/bilateral-simultaneous-endoscopic-carpal-tunnel-release-mean-time-to-resume-activities-of-daily-living-and-return-to-work
#13
B Degeorge, R Coulomb, P Kouyoumdjian, O Mares
The purpose of this study was to determine the time needed to return to personal and professional activities after bilateral simultaneous endoscopic carpal tunnel release. During a retrospective, single-center study, we included a cohort of 30 patients (60 wrists). Patients were evaluated clinically (pain, paresthesia) and functionally (QuickDASH score) pre- and postoperatively. At the last follow-up, patients completed a questionnaire regarding the time needed to resume personal activities using the ADL scale (feeding, personal hygiene and dressing) and return to work...
March 19, 2018: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/29554696/clozapine-induced-dress-syndrome-a-case-series-from-the-amsp-multicenter-drug-safety-surveillance-project
#14
B Sanader, R Grohmann, P Grötsch, T Schumann, S Toto, P Fernando, S Stübner
Drug reaction with eosinophilia and systemic symptoms (DRESS) is an infrequent, but severe, adverse drug-induced reaction which occurs due to massive T-cell stimulation resulting in cytotoxicity and eosinophil activation and recruitment. The incidence is 0.4 cases per 100, 0000 in the general population; the mortality rate is up to 10%. Therefore, we believe that recognizing this syndrome is of particular importance. The problem we notice is that DRESS is often seen and described in patients receiving rheumatologic or anticonvulsant drugs, but very rarely in psychiatric hospitals, where Clozapine is frequently used, and that is the importance of this paper...
March 19, 2018: Pharmacopsychiatry
https://www.readbyqxmd.com/read/29546073/association-between-hla-b-alleles-and-carbamazepine-induced-maculopapular-exanthema-and-severe-cutaneous-reactions-in-thai-patients
#15
Chonlaphat Sukasem, Chonlawat Chaichan, Thapanat Nakkrut, Patompong Satapornpong, Kanoot Jaruthamsophon, Thawinee Jantararoungtong, Napatrupron Koomdee, Suthida Sririttha, Sadeep Medhasi, Sarawut Oo-Puthinan, Ticha Rerkpattanapipat, Jettanong Klaewsongkram, Pawinee Rerknimitr, Papapit Tuchinda, Leena Chularojanamontri, Napatra Tovanabutra, Apichaya Puangpetch, Wichai Aekplakorn
The HLA-B ∗ 15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients. The HLA-B alleles associated with carbamazepine-induced maculopapular exanthema (MPE) and the drug reaction with eosinophilia and systemic symptoms (DRESS) among the Thai population have never been reported. The aim of the present study was to carry out an analysis of the involvement of HLA-B alleles in carbamazepine-induced cutaneous adverse drug reactions (cADRs) in the Thai population...
2018: Journal of Immunology Research
https://www.readbyqxmd.com/read/29541744/association-between-hla-b-1301-and-dapsone-induced-cutaneous-adverse-drug-reactions-a-systematic-review-and-meta-analysis
#16
Wimonchat Tangamornsuksan, Manupat Lohitnavy
Importance: Dapsone-induced hypersensitivity syndrome (DHS) is a life-threatening adverse drug reaction. Based on available epidemiologic studies, HLA genotypes may play an important role in DHS. Objective: To assess the association between HLA-B*1301 and dapsone-induced cutaneous adverse drug reactions (cADRs). Data Sources: Human studies investigating associations between HLA-B*1301 and dapsone-induced cADRs were systematically searched without language restriction from the inception of each database until September 12, 2017, in PubMed, the Human Genome Epidemiology Network), and the Cochrane Library...
April 1, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29527023/drug-reaction-with-eosinophilia-and-systemic-symptoms-an-update-and-review-of-recent-literature
#17
Abhishek De, Murlidhar Rajagopalan, Aarti Sarda, Sudip Das, Projna Biswas
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, is also known as drug induced hypersensitivity syndrome and by various other names. It is now recognised as one of the severe cutaneous adverse reaction (SCAR) and can be potentially life-threatening. Historically, it was most frequently linked with phenytoin and was initially described as phenytoin hypersensitivity syndrome. However, it was later found to be caused by various other medications. Anticonvulsants and sulfonamides are the most common offender...
January 2018: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/29521632/overexpression-of-cytotoxic-proteins-correlates-with-liver-function-impairment-in-patients-with-drug-reaction-with-eosinophilia-and-systemic-symptoms-dress
#18
Fanping Yang, Sheng-An Chen, Xiaojin Wu, Qingyuan Zhu, Xiaoqun Luo
Drug reaction with eosinophilia and systemic symptoms (DRESS) is characterised by skin rash and multivisceral involvement. The liver is the organ most frequently affected and the degree of liver function impairment often correlates with the mortality rate of DRESS. We aimed to examine the expression of cytotoxic proteins, including soluble Fas ligand (sFasL), TNF-α, granulysin, perforin, and granzyme B in the sera and skin lesions of patients with DRESS and evaluate their clinical significance. Our cohort consisted of 21 patients with DRESS and control groups including 39 patients with Stevens-Johnson syndrome/toxic epidermal necrolysis, 21 patients with maculopapular eruption, and 29 normal controls...
February 1, 2018: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/29519170/dress-syndrome-a-detailed-insight
#19
Sapan Kumar Behera, Saibal Das, Alphienes Stanley Xavier, Sandhiya Selvarajan
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a serious and potentially fatal adverse effect to therapeutic medications. The incidence of this condition varies among different ethnicities because of the difference in the genetic makeup. Though fever, rash and eosinophilia are essential features for the diagnosis of this syndrome, these vary from patient to patient along with the involvement of various organs such as liver, kidney, lungs, pancreas, etc. Some of the atypical features are dysphagia, agranulocytosis, and chylous ascites...
March 15, 2018: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/29480028/risks-associated-with-lamotrigine-prescription-a-review-and-personal-observations
#20
Gordon Parker
OBJECTIVES: To detail some serious lamotrigine side effects and their management, and raise awareness about the possible lack of quality control of some brands of lamotrigine. METHODS: A literature review is provided and some personal observations added. RESULTS: While most psychiatrists are aware of the risks of Stevens-Johnson syndrome (SJS), awareness of two other serious side effects - toxic epidermal necrosis (TEN) and drug-related eosinophilia and systemic symptoms (DRESS) - is seemingly lower...
February 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
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