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https://www.readbyqxmd.com/read/29679939/semi-volatile-organic-compounds-in-the-snow-of-russian-arctic-islands-archipelago-novaya-zemlya
#1
A T Lebedev, D M Mazur, O V Polyakova, D S Kosyakov, A Yu Kozhevnikov, T B Latkin, I Andreeva Yu, V B Artaev
Environmental contamination of the Arctic has widely been used as a worldwide pollution marker. Various classes of organic pollutants such as pesticides, personal care products, PAHs, flame retardants, biomass burning markers, and many others emerging contaminants have been regularly detected in Arctic samples. Although numerous papers have been published reporting data from the Canadian, Danish, and Norwegian Arctic regions, the environmental situation in Russian Arctic remains mostly underreported. Snow analysis is known to be used for monitoring air pollution in the regions with cold climate in both short-term and long-term studies...
April 18, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29679918/decentralisation-and-waste-flows-a-welfare-approach
#2
Laura Levaggi, Rosella Levaggi, Carmine Trecroci
We analyse incentives, equilibria and implications of the governance framework for the disposal of municipal solid waste in an N-Region model where waste mobility is allowed. The key decisions revolve around the flow of waste between regions and the externalities associated with its final disposal. Two different institutional settings are considered: a centralised framework where a central planner takes all the decisions and a decentralised model where each region decides on its waste flows. When the regions are characterised by different levels of efficiency in the final treatment of waste, a certain degree of mobility might allow to reap the benefits of higher efficiency...
April 18, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29679888/effects-of-thermo-order-mechanical-coupling-on-band-structures-in-liquid-crystal-nematic-elastomer-porous-phononic-crystals
#3
Shuai Yang, Ying Liu
Liquid crystal nematic elastomers are one kind of smart anisotropic and viscoelastic solids simultaneously combing the properties of rubber and liquid crystals, which is thermal sensitivity. In this paper, the wave dispersion in a liquid crystal nematic elastomer porous phononic crystal subjected to an external thermal stimulus is theoretically investigated. Firstly, an energy function is proposed to determine thermo-induced deformation in NE periodic structures. Based on this function, thermo-induced band variation in liquid crystal nematic elastomer porous phononic crystals is investigated in detail...
April 5, 2018: Ultrasonics
https://www.readbyqxmd.com/read/29679839/xenon-detection-in-human-blood-analytical-validation-by-accuracy-profile-and-identification-of-critical-storage-parameters
#4
Cécile Frampas, Julia Ney, Mark Coburn, Marc Augsburger, Vincent Varlet
Xenon is a rare, mostly inert, noble gas that has applications in a wide range of fields, including medicine. Xenon acts on the human body as a useful organ-protective and anesthetic agent and has also been previously studied for potential applications in fields such as optics, aerospace and medical imaging. Recently, it was discovered that xenon can boost erythropoietin production, and it has been used as a performance-enhancing agent in international sports competitions such as the Sochi Olympic Games. Therefore, screening methods to detect the misuse of xenon by analysis of biological samples and to monitor anesthesia kinetics and efficiency are being investigated...
April 13, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29679829/fulfilling-spawning-flow-requirements-for-potamodromous-cyprinids-in-a-restored-river-segment
#5
Isabel Boavida, Joaquim B Jesus, Vítor Pereira, Cátia Santos, Marisa Lopes, Rui M V Cortes
The Baixo Sabor hydroelectric scheme was recently constructed (began operating in 2015), blocking fish migration immediately at the river mouth. As a compensation measure for spawning habitat loss the Vilariça River which confluences with Sabor River, immediately downstream from the Baixo Sabor scheme, was chosen for rehabilitation site as an attempt to replace the spawning grounds lost in Sabor River for the potamodromous cyprinid Iberian barbel (Luciobarbus bocagei). Restoration activities included: placement of submerged weirs with fish ramps to increase the lotic/lentic sequence, bank reinforcement, boulder placement and river water profile increase...
April 18, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29679819/submarine-groundwater-discharge-and-chemical-behavior-of-tracers-in-laizhou-bay-china
#6
Yan Zhang, Hailong Li, Xuejing Wang, Chaoyue Wang, Kai Xiao, Wenjing Qu
Naturally occurring radon (222 Rn) and radium isotopes are widely used to trace water mixing and submarine groundwater discharge (SGD) in the coastal zones. However, their activities in groundwater are variable both spatially and temporally. Here, time series sampling of 222 Rn and radium was conducted to investigate their behavior in intertidal groundwater of Laizhou Bay, China. The result shows that groundwater redox conditions have an important impact on the behavior of tracers. The activities of tracers will decrease under oxidizing conditions and increase under reducing conditions...
April 18, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29679818/the-2014-integrated-field-exercise-of-the-comprehensive-nuclear-test-ban-treaty-revisited-the-case-for-data-fusion
#7
Jonathan L Burnett, Harry S Miley, Theodore W Bowyer, Ian M Cameron
The International Monitoring System of the Preparatory Commission for the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) uses a global network of radionuclide monitoring stations to detect evidence of a nuclear explosion. The two radionuclide technologies employed-particulate and noble gas (radioxenon) detection-have applications for data fusion to improve detection of a nuclear explosion. Using the hypothetical 0.5 kT nuclear explosive test scenario of the CTBTO 2014 Integrated Field Exercise, the intrinsic relationship between particulate and noble gas signatures has been examined...
April 18, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29679805/poly-l-lysine-modified-cryogels-for-efficient-bilirubin-removal-from-human-plasma
#8
Mehmet Emin Çorman
In this study, poly-l-lysine (PLL) immobilized PHEMA cryogel was designed for the specific bilirubin removal from human plasma. The surface of PHEMA cryogels is surrounded by PLL chains to enhance specific binding of bilirubin molecules via specific complementary electrostatic interactions. The functionalization of the PHEMA cryogel was carried out by direct coupling of PLL to pre-activated OH-group of the HEMA alcohol units via carbodiimide activation. Prior to removal of bilirubin from human plasma, the optimization parameters including, initial bilirubin concentration, flow rate, temperature, ionic strength, and adsorption rates on adsorption of PLL-PHEMA cryogel were investigated from the aqueous medium...
April 5, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29679786/simultaneous-analysis-of-historical-emerging-and-novel-brominated-flame-retardants-in-food-and-feed-using-a-common-extraction-and-purification-method
#9
Emmanuelle Bichon, Ingrid Guiffard, Anaïs Vénisseau, Elodie Lesquin, Vincent Vaccher, Philippe Marchand, Bruno Le Bizec
Brominated Flame Retardants (BFRs) are still widely used for industrial purposes. These contaminants may enter the food chain where they mainly occur in food of animal origin. The aim of our work was to provide a unique method able to quantify the widest range of BFRs in feed and food items. After freeze-drying and grinding, a pressurized liquid extraction was carried out. The extract was purified on acidified silica, Florisil® and carbon columns, the four separated fractions were analyzed by gas and liquid chromatography coupled to high resolution and tandem mass spectrometry...
April 13, 2018: Chemosphere
https://www.readbyqxmd.com/read/29679766/aminoacyl-trna-synthetase-complex-interacting-multifunctional-protein-1-simultaneously-binds-glutamyl-prolyl-trna-synthetase-and-scaffold-protein-aminoacyl-trna-synthetase-complex-interacting-multifunctional-protein-3-of-the-multi-trna-synthetase-complex
#10
Margaret A Schwarz, Daniel D Lee, Seamus Bartlett
Higher eukaryotes have developed extensive compartmentalization of amino acid (aa) - tRNA coupling through the formation of a multi-synthetase complex (MSC) that is composed of eight aa-tRNA synthetases (ARS) and three scaffold proteins: aminoacyl tRNA synthetase complex interacting multifunctional proteins (AIMP1, 2 and 3). Lower eukaryotes have a much smaller complex while yeast MSC consists of only two ARS (MetRS and GluRS) and one ARS cofactor 1 protein, Arc1p (Simos et al., 1996), the homolog of the mammalian AIMP1...
April 18, 2018: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/29679754/serum-25-hydroxyvitamin-d-and-breast-cancer-risk-by-pathological-subtype-mcc-spain
#11
Virginia Lope, Adela Castelló, Antonio Mena-Bravo, Pilar Amiano, Nuria Aragonés, Tania Fernández-Villa, Marcela Guevara, Trinidad Dierssen-Sotos, Guillermo Fernandez-Tardón, Gemma Castaño-Vinyals, Rafael Marcos-Gragera, Víctor Moreno, Dolores Salas-Trejo, Marian Diaz-Santos, Madalen Oribe, Isabel Romieu, Manolis Kogevinas, Feliciano Priego-Capote, Beatriz Pérez-Gómez, Marina Pollán
Epidemiologic evidence on the association between vitamin D and breast cancer is still inconclusive. This study analyzes the association between serum 25-hydroxyvitamin D (25(OH)D) and breast cancer risk by pathologic subtype, stage at diagnosis and specific breast cancer risk factors. We conducted a population-based multicase-control study where 546 histologically-confirmed breast cancer cases and 558 population controls, frequently matched by geographic area, age and body mass index, were recruited in 12 Spanish provinces (MCC-Spain)...
April 18, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29679735/age-dependent-effects-of-brain-stimulation-on-network-centrality
#12
Daria Antonenko, Till Nierhaus, Marcus Meinzer, Kristin Prehn, Axel Thielscher, Bernd Ittermann, Agnes Flöel
Functional magnetic resonance imaging (fMRI) studies have suggested that advanced age may mediate the effects of transcranial direct current stimulation (tDCS) on brain function. However, studies directly comparing neural tDCS effects between young and older adults are scarce and limited to task-related imaging paradigms. Resting-state (rs-) fMRI, that is independent of age-related differences in performance, is well suited to investigate age-associated differential neural tDCS effects. Three "online" tDCS conditions (anodal, cathodal, sham) were compared in a cross-over, within-subject design, in 30 young and 30 older adults...
April 18, 2018: NeuroImage
https://www.readbyqxmd.com/read/29679703/pc-pvt-2-0-an-updated-platform-for-psychomotor-vigilance-task-testing-analysis-prediction-and-visualization
#13
Jaques Reifman, Kamal Kumar, Maxim Y Khitrov, Jianbo Liu, Sridhar Ramakrishnan
BACKGROUND: The psychomotor vigilance task (PVT) has been widely used to assess the effects of sleep deprivation on human neurobehavioral performance. To facilitate research in this field, we previously developed the PC-PVT, a freely available software system analogous to the "gold-standard" PVT-192 that, in addition to allowing for simple visual reaction time (RT) tests, also allows for near real-time PVT analysis, predictions, and visualization in a personal computer (PC)...
April 18, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29679682/bitter-and-sweet-tasting-molecules-it-s-complicated
#14
REVIEW
Antonella Di Pizio, Yaron Ben Shoshan-Galeczki, John E Hayes, Masha Y Niv
"Bitter" and "sweet" are frequently framed in opposition, both functionally and metaphorically, in regard to affective responses, emotion, and nutrition. This oppositional relationship is complicated by the fact that some molecules are simultaneously bitter and sweet. In some cases, a small chemical modification, or a chirality switch, flips the taste from sweet to bitter. Molecules humans describe as bitter are recognized by a 25 member subfamily of class A G-protein coupled receptors (GPCRs) known as TAS2Rs...
April 18, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29679647/a-new-micro-holder-device-for-local-drug-delivery-during-in-vivo-whole-cell-recordings
#15
María Sáez, Maya Ketzef, Javier Alegre-Cortés, Ramón Reig, Gilad Silberberg
Focal administration of pharmacological agents during in vivo recordings is a useful technique to study the functional properties of neural microcircuits. However, the lack of visual control makes this task difficult and inaccurate, especially when targeting small and deep regions where spillover to neighboring regions is likely to occur. An additional problem with recording stability arises when combining focal drug administration with in vivo intracellular recordings, which are highly sensitive to mechanical vibrations...
April 18, 2018: Neuroscience
https://www.readbyqxmd.com/read/29679569/ddx1-regulates-alternative-splicing-and-insulin-secretion-in-pancreatic-%C3%AE-cells
#16
Wen Zhong, Zonghong Li, Maoge Zhou, Tao Xu, You Wang
DEAD-box helicase 1 (DDX1) is a multifunction protein involved in diverse cellular processes including transcription, viral replication, mRNA/miRNA processing, and tRNA splicing. Here, we report a novel function of DDX1 in mRNA alternative splicing in pancreatic β cells. By performing integrated data analysis of high-throughput RNA sequencing (RNA-Seq), and cross-linking and immunoprecipitation coupled with deep sequencing (CLIP-Seq), we identify hundreds of alternative splicing genes that are targeted by DDX1...
April 18, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29679511/light-availability-impacts-structure-and-function-of-phototrophic-stream-biofilms-across-domains-and-trophic-levels
#17
Mia M Bengtsson, Karoline Wagner, Clarissa Schwab, Tim Urich, Tom J Battin
Phototrophic biofilms are ubiquitous in freshwater and marine environments where they are critical for biogeochemical cycling, food webs and in industrial applications. In streams, phototrophic biofilms dominate benthic microbial life and harbor an immense prokaryotic and eukaryotic microbial biodiversity with biotic interactions across domains and trophic levels. Here, we examine how community structure and function of these biofilms respond to varying light availability, as the crucial energy source for phototrophic biofilms...
April 21, 2018: Molecular Ecology
https://www.readbyqxmd.com/read/29679502/new-paradigms-in-adenosine-receptor-pharmacology-allostery-oligomerization-and-biased-agonism
#18
REVIEW
Elizabeth A Vecchio, Jo-Anne Baltos, Anh T N Nguyen, Arthur Christopoulos, Paul J White, Lauren T May
Adenosine receptors (ARs) are a family of G protein-coupled receptors (GPCRs) containing four subtypes (A1 AR, A2A AR, A2B AR and A3 AR), all of which bind the ubiquitous nucleoside adenosine. ARs play an important role in physiology and pathophysiology and therefore represent attractive drug targets for a range of conditions. The theoretical framework surrounding AR drug action now extends beyond the notion of prototypical agonism and antagonism to encompass more complex pharmacological concepts. New paradigms include allostery, whereby ligands bind a topographically distinct receptor site from that of the endogenous agonist, homomeric or heteromeric interactions across receptor oligomers and biased agonism; that is, ligand-dependent differential intracellular signalling...
April 21, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29679498/7t-ultra-high-field-body-mr-imaging-with-an-8-channel-transmit-32-channel-receive-radiofrequency-coil-array
#19
Stefan H G Rietsch, Stephan Orzada, Stefan Maderwald, Sascha Brunheim, Bart W J Philips, Tom W J Scheenen, Mark E Ladd, Harald H Quick
PURPOSE: In this work a combined body coil array with 8 transmit/receive (Tx/Rx) meander elements and with 24 receive-only (Rx) loops (8Tx/32Rx) was developed and evaluated in comparison to an 8-channel transmit/receive body array (8Tx/Rx) based on meander elements serving as the reference standard. METHODS: Systematic evaluation of the RF array was performed on a body-sized phantom. Body imaging at 7T was performed in 6 volunteers in the body regions pelvis, abdomen, and heart...
April 21, 2018: Medical Physics
https://www.readbyqxmd.com/read/29679453/simultaneous-analysis-of-multiple-urinary-biomarkers-for-the-evaluation-of-oxidative-stress-by-automated-on-line-in-tube-solid-phase-microextraction-coupled-with-negative-positive-ion-switching-mode-lc-ms-ms
#20
Akihiro Saito, Mariko Hamano, Hiroyuki Kataoka
This study described an automated on-line method for the simultaneous determination of 8-isoprostane, 8-hydroxy-2'-deoxyguanosine, and 3-nitro-l-tyrosine in human urine. The method involves in-tube solid-phase microextraction using a Carboxen 1006 PLOT capillary column as an extraction device, followed by liquid chromatography with tandem mass spectrometry using a CX column and detection in the negative/positive switching ion-mode by multiple reaction monitoring. Using their stable isotope-labeled internal standards, each of these oxidative stress biomarkers showed good linearity from 0...
April 20, 2018: Journal of Separation Science
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