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Molly Frances Battistelli, Sara Magnusson, M Antonia Biggs, Lori Freedman
CONTEXT: Access to abortion care in the United States varies according to multiple factors, including location, state regulation and provider availability. In 2013, California enacted a law that authorized nurse practitioners (NPs), certified nurse-midwives (CNMs) and physician assistants (PAs) to provide first-trimester aspiration abortions; little is known about organizations' experiences in implementing this policy change. METHODS: Beginning 10 and 24 months after implementation of the new law, semistructured interviews were conducted with 20 administrators whose five organizations trained and employed NPs, CNMs and PAs as providers of aspiration abortions...
February 14, 2018: Perspectives on Sexual and Reproductive Health
Morgan Philp, Ronald Shimmon, Mark Tahtouh, Shanlin Fu
Synthetic cathinones are a large class of new psychoactive substances (NPS) that are increasingly prevalent in drug seizures made by law enforcement and other border protection agencies globally. Color testing is a presumptive identification technique indicating the presence or absence of a particular drug class using rapid and uncomplicated chemical methods. Owing to their relatively recent emergence, a color test for the specific identification of synthetic cathinones is not currently available. In this study, we introduce a protocol for the presumptive identification of synthetic cathinones, employing three aqueous reagent solutions: copper(II) nitrate, 2,9-dimethyl-1,10-phenanthroline (neocuproine) and sodium acetate...
February 5, 2018: Journal of Visualized Experiments: JoVE
Seon Young Choi, Pan Dong Ryu, Sang-Woo Joo, So Yeong Lee
MicroRNAs that bind to mRNA are important post-transcriptional regulators that control gene expression by degradation or suppressing translation of target mRNAs. Several studies indicate that nanoparticles (NPs) induce alterations in microRNA expression relating to cell processes including cell development and progressive diseases. However, the alteration of microRNA expression by surface-modified gold nanoparticles (AuNPs) in A549 cells has not been reported. In order to investigate the patterns of microRNA expression, we analyzed data from microRNA arrays using cells treated with citrate- or chitosan-AuNPs...
April 1, 2018: Journal of Nanoscience and Nanotechnology
Ayman Yousef, Robert M Brooks, Ahmed Abutaleb, Salem S Al-Deyab, Mohamed H El-Newehy
Electrospinning has been used to synthesize cobalt-chromium carbide nanoparticles (NPs)-doped carbon nanofibers (CNFs) (Composite). Electrospun mat comprising of cobalt acetate, chromium acetate and poly(vinyl alcohol) (PVA) has been carbonized at low temperature (850 °C) for 3 h under argon atmosphere to produce the introduced composite. The process was achieved at low temperature due to the presence of cobalt as an activator. Field emission scanning electron microscope (FE-SEM), X-ray diffractometry (XRD), and transmission electron microscopy (TEM) equipped with EDX techniques were used to determine the products characteristics...
April 1, 2018: Journal of Nanoscience and Nanotechnology
Shengmei Yang, Fengxia Xiong, Kui Chen, Yanan Chang, Xue Bai, Wenyan Yin, Weihong Gu, Qianyuan Wang, Juan Li, Guogang Chen
The application of nano-products in the food industry increases the risk of people exposed to nanoparticles. Titanium dioxide nanoparticles (T-NPs) are typically and widely used in food field, while fullerenol nanoparticles (F-NPs) have great promise to be used as food additives. Therefore, it is necessary and important to understand the safety of T-NPs and F-NPs in foods. In the present study, Caco-2 gut epithelial cell line was selected as a model to investigate the impact of T-NPs and F-NPs. The viability and proliferation of Caco-2 gut epithelial cells incubated with different concentrations of T-NPs and F-NPs were observed...
April 1, 2018: Journal of Nanoscience and Nanotechnology
Zhengwei Luo, Min Zhu, Mulin Guo, Zhouyang Lian, Wen Tong, Jirong Wang, Binghua Zhang, Wuji Wei
The activity inhibition of fungi by ZnO nanoparticles (NPs) has shown huge potential applications in the area of hygienic coatings. However, the inhibition efficiency was limited due to the agglomeration of NPs. To obtain well-dispersed and highly stabilized ZnO nanofluids, ZnO NPs were capped with four kinds of surfactants under ultrasonication. The capping procedure was optimized by varying the dosage of surfactants, the ultrasonic duration, ultrasonic power and temperature. Capped ZnO nanofluids were then used for the inhibition of Trichoderma viride...
April 1, 2018: Journal of Nanoscience and Nanotechnology
Xiujuan Wu, Yu Cai, Chao Wang, Li Fan, Qianyun Tang, Xiaochen Dong, Qi Zhang
Herein, an small-molecule organic nanoparticles, BNTP NPs, has been synthesized. Due to its strong and broad absorption spectra and tumor targeting, BNTP NPs is used as a photothermal agent with photothermal conversion efficiency of 23.2%. BNTP NPs can target tumors, realize tumor diagnosis and suppress the growth of tumor effectively both in vitro and in vivo. Xenon lamp instead of laser is used as light source of BNTP NPs to make PTT safer. No obvious toxicity reaction is observed from histologic analysis and body weight of mice...
April 1, 2018: Journal of Nanoscience and Nanotechnology
Xiao-Ning Lin, Xinli Tian, Wang Li, Jin Sun, Feng Wei, Wei Feng, Zhi-Chun Huang, Xin-Hua Tian
Gliomas are the most common type of intracranial malignant tumor; however, current treatment approaches are often ineffective due to limited penetration of genes or drugs through the blood-brain barrier (BBB). Here we describe the synthesis of gelatin-siloxane nanoparticles (GS NPs) as candidate gene carriers through a two-step sol-gel process. To increase the efficiency of glioma targeting, human immunodeficiency virus-derived Tat, tumor-targeting aptamer (TTA)1, and polyethylene glycol (PEG) were conjugated to the GS NPs to generate Tat-TTA1-PEG-GS NPs...
April 1, 2018: Journal of Nanoscience and Nanotechnology
Tao Jiang, Ho-Man Kan, Komal Rajpura, Erica J Carbone, Yingcui Li, Kevin W-H Lo
Osteoarthritis is a severe and debilitating joint disease, which is characterized as results from damage and degeneration of the articular cartilage of the joint surfaces. The incidence of osteoarthritis is growing increasingly high while current treatment methods remain suboptimal. The major issue for current osteoarthritic medications is that patients frequently experience adverse, nonspecific side effects that are not a direct result of the specific pharmacological action of the drug. The treatment processes could be made more effective, safe, and comfortable if it were possible to deliver the drugs specifically to cartilage tissue...
April 1, 2018: Journal of Nanoscience and Nanotechnology
Puran Pandey, Sundar Kunwar, Mao Sui, Ming-Yu Li, Quanzhen Zhang, Jihoon Lee
As a promising candidate for the improved performance, silver nanoparticles (Ag NPs) have been successfully adapted in various applications such as photovoltaics, light emitting diodes (LEDs), sensors and catalysis by taking the advantage of their controllable plasmonic properties. In this paper, the control on the morphologies and optical properties of Ag NPs on c-plane sapphire (0001) is demonstrated by the systematic control of annealing temperature (between 200 and 950 °C) with 20 and 6 nm thick Ag films through the solid state dewetting...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Nguyen Dang Mao, Soon Young Lee, Hee Jae Shin, Lee Ku Kwac, Sang Cheol Ko, Hong Gun Kim, Hun Jeong
In this study, the monodisperse amorphous silica nanoparticles (SiO2 NPs) with uniform size distribution and high surface area were successfully synthesized from fly ash as a silica source by chemical sol-gel method. The influence of reaction conditions such as surfactant concentration, aging temperature (Ta), and aging time (Ta) on formation of SiO2 NPs was investigated. Through SEM characterization, it was founded that the uniform and small spherical SiO2 NPs with diameter of 20-30 nm could be synthesized at the appropriate CTAB content of 3 wt%, Ta of 60 °C, and Ta of 8 h...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Mani Jayanthi, Thirugnanam Lavanya, Nagarajan Anbil Saradha, Kaveri Satheesh, SriRangarajan Chenthamarai, Ramasamy Jayavel
In this article, cerium oxide nanoparticles (CeO2 NPs) and reduced graphene oxide nanocomposite have been fabricated through simple, easy and cost effective co-precipitation method. The structural, optical and morphological characterization provides the evidence of successful synthesis of CeO2 NPs and nanocomposite. X-ray photoelectron spectroscopic characterization provides useful information about the concentrations and proportions of Ce3+ and Ce4+ ions in nanoparticles as well as in nanocomposite. These studies provide an insight to understand enhanced photocatalytic activity of nanocomposite...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Pascal Pellen-Mussi, Sylvie Tricot-Doleux, Chrystelle Neaime, Nicolas Nerambourg, Francisco Cabello-Hurtado, Stéphane Cordier, Fabien Grasset, Sylvie Jeanne
CONTEXT: as a kind of non-metal oxide SiO2 NPs have been extensively used in biomedicine, pharmaceuticals and other industrial manufacturing fields, such as DNA delivery, cancer therapy… Our group had developed a method based on microemulsion process to prepare SiO2 NPs incorporating photonic or magnetic nanocrystals and luminescent nanosized inorganic metal atom clusters. However, the toxicity of nanoparticles is known to be closely related to their physico-chemical characteristics and chemical composition...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Sivakumar Allur Subramaniyan, Sunirmal Sheet, Mohanraj Vinothkannan, Dong Jin Yoo, Yang Soo Lee, Shah Ahmed Belal, Kwan Seob Shim
Platinum nanoparticles (Pt NPs) was synthesized via a facile and cost competitive ont-pot green mediated synthesis using cell free cultural filtrate (microgravity simulated grown Penicillium chrysogenum) as a reducing agent. The toxicity effect of synthesized Pt NPs toward myoblast C2C12 carcinoma cells was then investigated. The particle size analyzer (DLS) and transmission electron microscopy (TEM) results demonstrates that both NG-Pt NPs and MG-Pt NPS are spherical in shape with an average diameter of 15 nm and 8...
May 1, 2018: Journal of Nanoscience and Nanotechnology
Kyu Oh Kim, Ick Soo Kim
Nanostructured POSS-PEG nanoparticles (NPs, 42.4 nm ~) synthesized by formation of the urethane linkage between the monoisocyanate group (O═C═N-) of Polyhedral oligosilsesquioxane (POSS) macromers and the diol end groups (-OH) of polyethylene glycol (PEG) homopolymers as catalyzed by dibutyl tin dilaurate are of great interest for biomedical applications. However, NP materials based on nonorganic compounds can be cytotoxic. In this study, the preparation of PEG-POSS NPs followed the coating collagen assembly, which alleviates this problem...
June 1, 2018: Journal of Nanoscience and Nanotechnology
Xiangxin Xue, Jing Zhang, Lei Chen, Cuimei Zhao, Li Wang, Limin Chang
In this paper, the study of the Zn1-xNixO (x = 0, 0.01, 0.03, 0.05) nanoparticles as SERS active substrate has been reported. The structural, morphological and optical studies are carried out by XRD, XPS, SEM, UV-vis and Raman spectroscopy. The XRD spectra indicate that the four Zn1-xNixO nanoparticles (x = 0, 0.01, 0.03, 0.05) are all single wurtzite structure. XPS study further demonstrates that Ni atoms are successfully doped into ZnO lattice. We have observed strong SERS signals when the 4-mercaptobenzoic acid used as the probe molecules...
June 1, 2018: Journal of Nanoscience and Nanotechnology
Panupong Sangsuriyawong, Auttasit Tubtimtae, Veeramol Vailikhit, Pichanan Teesetsopon, Supab Choopun
Manganese2+-doped copper tin telluride nanoparticles (Mn2+:Cu2SnTe3 NPs), as an absorber layer, were grown using a chemical bath deposition (CBD) technique and demonstrated for solar cell applications. The cubical structure was formed on the WO3 surface with the band gap (Eg) of Cu2SnTe3 NPs decreased from 1.80 to 1.67 eV after Mn2+ doping. The photovoltaic property at 1 sun shows the efficiency (η) of 0.276%. The η was increased with reducing sunlight intensity due to the lower carrier recombination process at an electrode and electrolyte interface, which leads to the increasing η...
June 1, 2018: Journal of Nanoscience and Nanotechnology
Kai Zheng, Jubo Zhang, Yan Wang, Longxue Gao, Mingyu Di, Fang Yuan, Wenhui Bao, Tao Yang, Daxin Liang
In order to deal with pollution of organic dyes, magnetic Fe3O4 nanospheres (NPs) with an average diameter of 202 ± 0.5 nm were synthesized by a solvothermal method at 200 °C, and they can efficiently degrade organic dyes (methylene blue (MB), rhodamine B (RhB) and xylenol orange (XO)) aqueous solutions (20 mg/L) within 1 min. Based on this Fenton reagent, Fe3O4 NPs/biomass composite degradation column was made using sawdust as substrate, and it can efficiently degrade organic dyes continually. More importantly, the composite can be regenerated just by an ultrasonic treatment, and its degradation performance almost remains the same...
June 1, 2018: Journal of Nanoscience and Nanotechnology
M A Gondal, T A Fasasi, Umair Baig, A Mekki
In this work, pulsed laser ablation in liquid (PLAL) technique was applied to synthesize colloidal nanoparticles of zirconium oxide (ZrO2) in three different aqueous media (de-ionized water, ethanol and acetone). The structure, morphology, composition and optical properties of the synthesized nanoparticles were characterized by XRD, SEM, TEM, XPS, UV-Vis spectrophotometer and FT-IR analysis respectively. The structural analysis by XRD reveals the formation of mixture of monoclinic and tetragonal phases of nanocrystalline zirconia...
June 1, 2018: Journal of Nanoscience and Nanotechnology
Vinay Kumar Tripathi, Allur Subramaniyan Sivakumar, Anupam Dhasmana, Inho Hwang
Nanotechnology is a promptly growing field in this century, and it have been extensively used in several solicitations. Reactive oxygen species (ROS) generation is one of the important mechanism of action of nanoparticles. The excess ROS generation can induce oxidative stress, so the cells are unable to sustain the normal biological redox-regulated tasks. The high oxidative stress and ROS formation condition, damage the biological macromolecules, cell signaling pathways and finally leads to cell death or cancer initiation...
June 1, 2018: Journal of Nanoscience and Nanotechnology
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