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https://www.readbyqxmd.com/read/29679870/application-of-enteromorpha-polysaccharides-as-coagulant-aid-in-the-simultaneous-removal-of-cuo-nanoparticles-and-cu-2-effect-of-humic-acid-concentration
#1
Yuanxia Luo, Baoyu Gao, Qinyan Yue, Ruihua Li
Humic acid (HA) influences the aggregation and stability of nanoparticles (NPs), which determine the removal performance of NPs in coagulation. Consequently, in this study, the impact of HA concentration on the simultaneous removal of CuO NPs, Cu2+ , and natural organic matter (NOM) was investigated. Enteromorpha polysaccharides (Ep), as the novel recycling coagulant aid, were integrated with polyaluminum chloride (PAC) to treat composite contaminants in this coagulation process. Removal performance, floc properties, zeta potential, scanning electron microscope (SEM) images, and Fourier Transform Infrared Spectra (FT-IR) were measured and analyzed...
March 26, 2018: Chemosphere
https://www.readbyqxmd.com/read/29679666/glutathione-sensitive-hollow-mesoporous-silica-nanoparticles-for-controlled-drug-delivery
#2
Seyyed Pouya Hadipour Moghaddam, Mostafa Yazdimamaghani, Hamidreza Ghandehari
Tunable glutathione (GSH)-sensitive hollow mesoporous silica nanoparticles (HMSiO2 NPs) were developed using a structural difference-based selective etching strategy. These organosilica hollow nanoparticles contained disulfide linkages (S-S) in the outer shell which were degraded by GSH. The particles were compared with their nonGSH-sensitive tetraethyl orthosilicate (TEOS) HMSiO2 counterparts in terms of their synthesis method, characterization, DOX release profile, and in vitro cytotoxicity in MCF-7 breast cancer cells...
April 18, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29679033/innovatively-therapeutic-strategy-on-lung-cancer-by-daily-drinking-antioxidative-plasmon-induced-activated-water
#3
Chien-Kai Wang, Hsiao-Chien Chen, Sheng-Uei Fang, Chia-Wen Ho, Cheng-Jeng Tai, Chih-Ping Yang, Yu-Chuan Liu
Many human diseases are inflammation-related, such as cancer and those associated with aging. Previous studies demonstrated that plasmon-induced activated (PIA) water with electron-doping character, created from hot electron transfer via decay of excited Au nanoparticles (NPs) under resonant illumination, owns reduced hydrogen-bonded networks and physchemically antioxidative properties. In this study, it is demonstrated PIA water dramatically induced a major antioxidative Nrf2 gene in human gingival fibroblasts which further confirms its cellular antioxidative and anti-inflammatory properties...
April 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29678630/characterization-and-simulation-of-noise-in-pet-images-reconstructed-with-osem-development-of-a-method-for-the-generation-of-synthetic-images
#4
P Castro, C Huerga, P Chamorro, J Garayoa, M Roch, L Pérez
INTRODUCTION: The goals of the study are to characterize imaging properties in 2D PET images reconstructed with the iterative algorithm ordered-subset expectation maximization (OSEM) and to propose a new method for the generation of synthetic images. MATERIAL AND METHODS: The noise is analyzed in terms of its magnitude, spatial correlation, and spectral distribution through standard deviation, autocorrelation function, and noise power spectrum (NPS), respectively...
April 17, 2018: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/29678549/title-reversal-of-drug-resistance-by-planetary-ball-milled-pbm-nanoparticle-loaded-with-resveratrol-and-docetaxel-in-prostate-cancer
#5
Santosh Kumar Singh, James W Lillard, Rajesh Singh
The folate receptor (FR) is a valued target that is highly expressed in various cancers, which will expedite the development of ligand-receptor binding based cancer therapeutics. In the present investigation, through tissue microarray analysis, we report higher levels of folate receptor expression in prostate cancer (PCa) tissue derived from patients, which were minimal in normal tissue. For folate-receptor based targeted therapy of PCa, we generated novel planetary ball milled (PBM) nanoparticles (NPs) encapsulated with resveratrol (RES), and in combination with docetaxel (DTX) and conjugated with folic acid (FA) on the surface...
April 17, 2018: Cancer Letters
https://www.readbyqxmd.com/read/29678500/a-bench-top-automated-workstation-for-nucleic-acid-isolation-from-clinical-sample-types
#6
Nitu Thakore, Steve Garber, Arial Bueno, Peter Qu, Ryan Norville, Michael Villanueva, Darrell P Chandler, Rebecca Holmberg, Christopher G Cooney
Systems that automate extraction of nucleic acid from cells or viruses in complex clinical matrices have tremendous value even in the absence of an integrated downstream detector. We describe our bench-top automated workstation that integrates our previously-reported extraction method - TruTip - with our newly-developed mechanical lysis method. This is the first report of this method for homogenizing viscous and heterogeneous samples and lysing difficult-to-disrupt cells using "MagVor": a rotating magnet that rotates a miniature stir disk amidst glass beads confined inside of a disposable tube...
April 17, 2018: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29677825/fabrication-of-sb%C3%A2-s%C3%A2-hybrid-solar-cells-based-on-embedded-photoelectrodes-of-ag-nanowires-au-nanoparticles-composite
#7
Kang-Pil Kim, Dae-Kue Hwang, Sung-Ho Woo, Dae-Hwan Kim
The Ag nanowire (NW) + Au nanoparticle (NP)-embedded TiO2 photoelectrodes were adopted for conventional planar TiO2-based Sb2S3 hybrid solar cells to improve the cell efficiency. Compared to conventional planar TiO2-based Sb2S3 hybrid solar cells, the Ag NW + Au NP/TiO2-based Sb2S3 hybrid solar cells exhibited an improvement of approximately 40% in the cell efficiency due to the significant increase in both Jsc and Voc. These enhanced Jsc and Voc were attributed to the increased surface area, charge-collection efficiency, and light absorption by embedding the Ag NWs + Au NPs composite...
September 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29677745/one-pot-synthesis-of-magnesium-aminoclay-titanium-dioxide-nanocomposites-for-improved-photocatalytic-performance
#8
Vu K H Bui, Duckshin Park, Vinh V Tran, Go-Woon Lee, Seo Yeong Oh, Yun Suk Huh, Young-Chul Lee
TiO2 nanoparticles (NPs) with their excellent photocatalytic performance are among the hottest research subjects for environmental-cleanup applications. In the present work, we developed a method of one-pot synthesis of magnesium aminoclay-titanium dioxide [MgAC-TiO2] nanocomposites in ethanol solution and then treated the obtained nanocomposites in a 350 °C muffle furnace for 3 hours. The obtained X-ray diffraction (XRD) patterns confirmed the growth of the anatase TiO2 NPs in the amorphous MgAC phase. In the scanning electron microscopy (SEM) morphological observation, the MgAC-TiO2 nanocomposites exhibited an aggregate form of 246...
September 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29677597/the-systematic-evaluation-of-size-dependent-toxicity-and-multi-time-biodistribution-of-gold-nanoparticles
#9
Xiaomin Li, Zhenpeng Hu, Jinlong Ma, Xinyu Wang, Yapei Zhang, Wei Wang, Zhi Yuan
As a promising nanomaterial, gold nanoparticles (Au NPs) have been widely applied in diagnosis, drug and gene delivery, and photothermal therapy. However, the toxicity and biodistribution profile of differently sized Au NPs still remains controversial and incomplete, thus hindering their further applications. Herein, a systematic evaluation of size effect on toxicity and multi-time (from 4 h to 90 days) biodistribution of Au NPs ranging from 6.2 nm to 61.2 nm was conducted. The in vitro toxicity by MTT assays manifested that toxicity could be distinctly observed and increased with size decreasing when the dose of Au NPs reached up to a certain amount (1 mM)...
April 4, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29677594/mechanisms-of-oxidative-stress-caused-by-cuo-nanoparticles-to-membranes-of-the-bacterium-streptomyces-coelicolor-m145
#10
Xiaomei Liu, Jingchun Tang, Lan Wang, John P Giesy
Toxic effects of widely used CuO nanoparticles (NPs) on the genus Streptomyces has been seldom studied. This work investigated toxicities of several sizes of CuO nanoparticles (NPs) to Streptomyces coelicolor M145 (S. coelicolor M145). Compared with NPs, toxicity of micrometer-sized CuO on M145 was trivial. In 0.9% NaCl, when the concentration of CuO NPs was 100 mg/L, survival of bacteria increased from 18.3% in 20 nm particles to 31.1% in 100 nm particles. With increasing concentrations of CuO, the level of ROS gradually increased and there were significant differences (p < 0...
April 17, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29677573/evidence-on-the-effectiveness-of-mosses-for-biomonitoring-of-microplastics-in-fresh-water-environment
#11
F Capozzi, R Carotenuto, S Giordano, V Spagnuolo
Mosses are well known as biomonitors of fresh water for metal pollutants, but no studies were reported so far about their ability to intercept plastic particles, although this kind of pollution has become an urgent issue worldwide. In the present work, the interaction between the moss Sphagnum palustre L. cultured in vitro and polystyrene nanoparticles (NPs) was studied for the first time in a laboratory experiment, in the view of using moss transplants for detecting microplastics in fresh water environments...
April 14, 2018: Chemosphere
https://www.readbyqxmd.com/read/29677542/innovative-perception-on-using-tiron-to-modulate-the-hepatotoxicity-induced-by-titanium-dioxide-nanoparticles-in-male-rats
#12
Ashraf Morgan, Marwa A Ibrahim, Mona K Galal, Hanan A Ogaly, Reham M Abd-Elsalam
The extensive application of titanium dioxide nanoparticles (TiO2 NPs) in the food industry arouses a debate regarding the probable risk associated with their use. Several recent studies reported that most nanoparticles (NPs) have adverse actions on the liver. The objective of this study is to examine whether Tiron plays a modulatory role against apoptotic damage induced by TiO2 NPs in rat livers. Forty rats were randomly divided into 4 groups; a control group received phosphate-buffered saline, an intoxicated group received 100 mg/kg/day of TiO2 NPs for 60 days, a treated group received 470 mg/kg/day of Tiron for the last 14 days after TiO2 NPs administration, and a Tiron group received Tiron only as previously mentioned...
April 17, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29677441/homologous-mirna-analyses-using-a-combinatorial-nanosensor-array-with-two-dimensional-nanoparticles
#13
Mustafa Salih Hizir, Nidhi Nandu, Mehmet Veysel Yigit
A novel combinatorial nanosensor array for miRNA analyses was assembled using the intrinsic non-covalent interactions of unmodified two-dimensional nanoparticles. Discrimination of nine miRNA analogs with as little as a single nucleotide difference was demonstrated under four hours. All nine targets were identified simultaneously with 95% confidence. The developed nanotechnology offered identification and quantification of unknown targets with unknown concentration. Discrimination of target mixtures from low-to-high ratios was demonstrated...
April 20, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29676908/fluorine-grafted-cu7s4-au-heterodimers-for-multimodal-imaging-guided-photothermal-therapy-with-high-penetration-depth
#14
Jiabin Cui, Rui Jiang, Chang Guo, Xilin Bai, Suying Xu, Leyu Wang
We report the multifunctional nanocomposites (NCs) consisting of 19F-moieties grafted Cu7S4-Au nanoparticles (NPs) through click chemistry for sensitive and negligible background 19F-magnetic resonance imaging (19F-MRI) and computed tomography (CT) imaging guided photothermal therapy. The localized surface plasmon resonance (LSPR) peak can be reasonably tuned to the in vivo transparent window (800-900 nm) by coupling Au NPs (<10 nm, LSPR 530 nm) with Cu7S4 NPs (<15 nm, LSPR 1500 nm) into the Cu7S4-Au heterodimers...
April 20, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29676776/gene-expression-analysis-of-neuropeptides-in-oral-mucosa-during-periodontal-disease-in-nonhuman-primates
#15
John Ferrin, Jeffrey L Ebersole, Sreenatha Kirakodu, David Jensen, Ahmad Al-Attar, Rebecca Peyyala, M John Novak, Dolph Dawson, Mohanad Al-Sabbagh, Arnold J Stromberg, Luis Orraca, Janis Gonzalez-Martinez, Armando Burgos, Octavio A Gonzalez
BACKGROUND: Neuropeptides (NPs) are innate pivotal regulators of the immunoinflammatory response. Nevertheless, their role in the pathogenesis of the periodontal disease remains unknown. We determined changes in gene expression of 10 NPs and 16 NP receptors (NPRs) coincident with the initiation, progression and resolution of periodontitis. METHODS: The ligature-induced periodontitis model was used in rhesus monkeys (n = 18). Gingival tissue samples were taken at baseline pre-ligature, 2 weeks and 1 month (Initiation), and 3 months (Progression) post-ligation...
April 20, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29676567/biomolecular-corona-dictates-a%C3%AE-fibrillation-process
#16
Alireza Lotfabadi, Mohammad Javad Hajipour, Hossein Derakhshankhah, Afshin Peirovi, Samaneh Saffar, Elnaz Shams, Elnaz Fatemi, Ebrahim Barzegari, Sajad Sarvari, Faezeh Moakedi, Maryam Ferdousi, Fatemeh Atyabi, Ali Akbar Saboury, Rassoul Dinarvand
Amyloid beta (Aβ), which forms toxic oligomers and fibrils in brain tissues of patients with Alzheimer's disease, is broadly used as a model protein to probe the effect of nanoparticles (NPs) on oligomerization and fibrillation process. However, majority of the reports in the field, ignored the effect of biomolecular corona on the fibrillogenesis of the Aβ proteins. Biomolecular corona, which is a layer composed of various types of biomolecules that covers surface of NPs upon their interaction with biological fluids, determines the biological fates of NPs...
April 20, 2018: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29676425/mechanistic-insights-into-the-interaction-between-energetic-oxygen-ions-and-nanosized-znfe-2-o-4-xas-xmcd-investigations
#17
Jitendra Pal Singh, Baljeet Kaur, Aditya Sharma, So Hee Kim, Sanjeev Gautam, Ramesh Chandra Srivastava, Navdeep Goyal, Weol Cheol Lim, H-J Lin, J M Chen, K Asokan, D Kanjilal, Sung Ok Won, Ik-Jae Lee, Keun Hwa Chae
The interactions of energetic ions with multi-cation compounds and their consequences in terms of changes in the local electronic structure, which may facilitate intriguing hybridization between O 2p and metal d orbitals and magnetic ordering, are the subject of debate and require a deep understanding of energy transfer processes and magnetic exchange mechanisms. In this study, nanocrystals of ZnFe2O4 were exposed to O7+ ions with an energy of 100 MeV to understand, qualitatively and quantitatively, the metal-ligand field interactions, cation migration and magnetic exchange interactions by employing X-ray absorption fine structure measurements and X-ray magnetic circular dichroism to get deeper mechanistic insights...
April 20, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29675946/plasma-proteomics-identifies-a-chemokine-storm-in-idiopathic-multicentric-castleman-disease
#18
Sheila K Pierson, Aaron J Stonestrom, Dustin Shilling, Jason Ruth, Christopher S Nabel, Amrit Singh, Yue Ren, Katie Stone, Hongzhe Li, Frits van Rhee, David C Fajgenbaum
Human Herpesvirus-8 (HHV-8)-negative/idiopathic multicentric Castleman disease (iMCD) is a poorly understood disease involving polyclonal lymphoproliferation with dysmorphic germinal centers, constitutional symptoms, and multi-organ failure. Patients can experience thrombocytopenia, anasarca, reticulin fibrosis, renal dysfunction, organomegaly, and normal immunoglobulin levels, - iMCD-TAFRO. Others experience thrombocytosis, milder effusions, and hypergammaglobulinemia, -iMCD-Not Otherwise Specified (iMCD-NOS)...
April 20, 2018: American Journal of Hematology
https://www.readbyqxmd.com/read/29675934/identifying-the-key-role-of-pyridinic-n-co-bonding-in-synergistic-electrocatalysis-for-reversible-orr-oer
#19
Xue-Rui Wang, Jie-Yu Liu, Zi-Wei Liu, Wei-Chao Wang, Jun Luo, Xiao-Peng Han, Xi-Wen Du, Shi-Zhang Qiao, Jing Yang
For many regenerative electrochemical energy-conversion systems, hybrid electrocatalysts comprising transition metal (TM) oxides and heteroatom-doped (e.g., nitrogen-doped) carbonaceous materials are promising bifunctional oxygen reduction reaction/oxygen evolution reaction electrocatalysts, whose enhanced electrocatalytic activities are attributed to the synergistic effect originated from the TM-N-C active sites. However, it is still ambiguous which configuration of nitrogen dopants, either pyridinic or pyrrolic N, when bonded to the TM in oxides, predominately contributes to the synergistic effect...
April 20, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29675543/improved-vaccine-induced-immune-responses-via-a-ros-triggered-nanoparticle-based-antigen-delivery-system
#20
Xiaoyu Liang, Jianwei Duan, Xuanling Li, Xiaowei Zhu, Youlu Chen, Xiaoli Wang, Hongfan Sun, Deling Kong, Chen Li, Jing Yang
Subunit vaccines that are designed based on recombinant antigens or peptides have shown promising potential as viable substitutes for traditional vaccines due to their better safety and specificity. However, the induction of adequate in vivo immune responses with appropriate effectiveness remains a major challenge for vaccine development. More recently, the implementation of a nanoparticle-based antigen delivery system has been considered a promising approach to improve the in vivo efficacy for subunit vaccine development...
April 20, 2018: Nanoscale
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