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https://www.readbyqxmd.com/read/29455071/the-use-of-satellite-data-to-measure-ultraviolet-b-penetrance-and-its-potential-association-with-age-of-multiple-sclerosis-onset
#1
Ofer Amram, Nadine Schuurman, Ellen Randall, Feng Zhu, Jameelah Saeedi, Peter Rieckmann, Irene Yee, Helen Tremlett
BACKGROUND: Studies have indicated an association between low Ultraviolet B (UVB) exposure and an increased risk of developing multiple sclerosis (MS). Few studies, however, have explored whether UVB exposure is associated with the age at MS symptom onset. OBJECTIVE: We investigated the potential association between cumulative early life ambient UVB exposure and age at MS onset, using satellite data to measure ambient UVB exposure. METHODS: Adult onset MS patients were selected from the University of British Columbia's MS genetic database (1980-2005)...
February 6, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29411629/clinical-texting-among-medical-trainees-of-the-university-of-british-columbia
#2
Danny Guo, Nam Phan, Kendall Ho, John Pawlovich, Neil Kitson
We believe cellphone text messages are commonly used in medical practice whether in rural or urban settings and that clinical photos are often attached to them. Our interest is the use of this technology to provide dermatology service to rural and remote British Columbia. Concern has been expressed about the security of confidential information and adequacy of privacy protection in such an application. We have found little published information about the extent of texting in rural and remote settings (and none in our jurisdiction) or the number and nature of privacy breaches that have actually occurred as a result...
February 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29410142/a-randomized-multi-center-study-assessing-the-educational-impact-of-a-computerized-interactive-hysterectomy-trainer-on-gynecology-residents
#3
Allan S Lichtman, William Parker, Barbara Goff, Neeraj Mehra, Eliane M Shore, Guylaine Lefebvre, Alexander Chiang, John Lenihan, Henk W R Schreuder
STUDY OBJECTIVE: To assess improvement of cognitive surgical knowledge of laparoscopic hysterectomy in post-graduate year (PGY) 1 and 2 gynecology residents who used an interactive computer-based Laparoscopic Hysterectomy Trainer. DESIGN: Multicenter prospective, randomized, controlled study (Canadian Taskforce Classification I). SETTING: Five Departments of Obstetrics and Gynecology: Keck School of Medicine of USC; University of California-Los Angeles; University of Washington; University of British Columbia; University of Toronto...
February 1, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29394462/sex-ethnic-and-age-specific-centile-curves-for-pqct-and-hr-pqct-derived-measures-of-bone-structure-and-strength-in-adolescents-and-young-adults
#4
Leigh Gabel, Lindsay A Nettlefold, Heather M Macdonald, Heather A McKay
There are presently no adolescent centile curves for bone parameters at the tibial midshaft using peripheral quantitative computed tomography (pQCT) or at the distal radius and tibia using high-resolution pQCT (HR-pQCT). Thus, we aimed to develop sex-, ethnic-, site- and age-specific centile curves for pQCT and HR-pQCT-derived bone outcomes for youth and young adults aged 10-21 years. We acquired pQCT scans (XCT3000) at the tibial midshaft (50% site) and HR-pQCT scans (XtremeCT, Scanco Medical) at the distal radius (7% site) and tibia (8% site) in a convenience sample of participants in the mixed-longitudinal University of British Columbia Healthy Bones III Study...
February 2, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29373595/hospitalizations-due-to-unintentional-transport-injuries-among-aboriginal-population-of-british-columbia-canada-incidence-changes-over-time-and-ecological-analysis-of-risk-markers
#5
Mariana Brussoni, M Anne George, Andrew Jin, Ofer Amram, Rod McCormick, Christopher E Lalonde
BACKGROUND: Worldwide, Indigenous people have disproportionately higher rates of transport injuries. We examined disparities in injury-related hospitalizations resulting from transport incidents for three population groups in British Columbia (BC): total population, Aboriginal off-reserve, and Aboriginal on-reserve populations. We also examined sociodemographic, geographic and ethnic risk markers for disparities. METHODS: We identified Aboriginal people through BC's universal health care insurance plan insurance premium group and birth and death record notations...
2018: PloS One
https://www.readbyqxmd.com/read/29354195/senior-medical-students-awareness-of-radiation-risks-from-common-diagnostic-imaging-examinations
#6
Elena Scali, John Mayo, Savvas Nicolaou, Michael Kozoriz, Silvia Chang
Background: Senior medical students represent future physicians who commonly refer patients for diagnostic imaging studies that may involve ionizing radiation. The radiology curriculum at the University of British Columbia provides students with broad-based knowledge about common imaging examinations. The purpose of this study was to investigate students' awareness of radiation exposures and risks. Methods: An anonymous multiple-choice cross-sectional questionnaire was distributed to final year medical students to assess knowledge of radiation from common diagnostic examinations and radiation-related risks following completion of the longitudinal radiology curriculum, carried out over the four years of medical training...
December 2017: Canadian Medical Education Journal
https://www.readbyqxmd.com/read/29341442/motivating-influences-and-ability-based-outcomes-of-dental-hygiene-baccalaureate-education-in-canada
#7
Z Kanji, D M Laronde
BACKGROUND: There is a scarcity of studies on Canadian baccalaureate dental hygienists. As discussions about baccalaureate education for dental hygiene continue on a national level, examining outcomes of earning a dental hygiene degree is paramount. OBJECTIVE: To investigate the motivating reasons and ability-based outcomes of earning a Bachelor of Dental Science in Dental Hygiene (BDSc) degree from the University of British Columbia (UBC), Canada. METHODS: UBC dental hygiene entry-to-practice (ETP) and degree-completion (DC) graduates (n = 116; 32%) from 1994 to 2016 participated in an online mixed-methods survey...
January 17, 2018: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/29236131/trends-in-incidence-and-long-term-outcomes-of-myelomeningocele-in-british-columbia
#8
Taylor North, Alexander Cheong, Paul Steinbok, Julia Ae Radic
PURPOSE: Myelomeningocele is typically a disabling condition that results in neurologic, orthopedic, and urologic morbidity. The aim of this study was to examine the trends over time in both incidence and outcomes of myelomeningocele (MMC) in British Columbia (BC). METHODS: A retrospective chart review was performed of all children with MMC followed in the British Columbia Children's Hospital (BCCH) Spinal Cord Clinic between 1971 and 2016. The incidence of new MMC cases and the long-term outcomes of MMC were compared between two 10-year cohorts...
December 13, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29200837/the-relationship-of-ssri-and-snri-usage-with-interstitial-lung-disease-and-bronchiectasis-in-an-elderly-population-a-case-control-study
#9
Ted Rosenberg, Rory Lattimer, Patrick Montgomery, Christian Wiens, Liran Levy
Background: The association between interstitial lung disease (ILD) and selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors (SSRI/SNRI) has been previously described in published case reports. However, its prevalence may be more common than expected. We examined the association between SSRI/SNRI usage and presence of ILD and or bronchiectasis (ILD/B) in an elderly population. Methods: We conducted a retrospective case series and case-control study involving all 296 eligible elderly patients in one primary care geriatric practice in Victoria, BC, Canada...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29184379/neurotransmitters-and-sodium-channelopathies-possible-link
#10
COMMENT
Michael F Hammer, Alejandra D C Encinas
Investigators from the University of British Columbia, Great Ormond Street Hospital for Children, and the National Hospital reported their findings on neurotransmitter deficiencies in two patients with mutations in voltage-gated sodium genes (SCN2A and SCN8A) discovered by whole exome sequencing.
November 2017: Pediatric Neurology Briefs
https://www.readbyqxmd.com/read/29120104/ethnicity-and-effectively-maintained-inequality-in-bc-universities
#11
Robert Sweet, Karen Robson, Maria Adamuti-Trache
As Canadian postsecondary systems have expanded they have become more institutionally differentiated. In British Columbia, distinctions are made between research-intensive universities (RIUs) and teaching-intensive universities with respect to resources, programming, and perceived prestige value. We employ an effectively maintained inequality framework to examine the role played by ethnicity in the competition for admission to RIUs. Our findings indicate that, together with socioeconomic status and gender, ethnicity is significantly related to RIU attendance rates...
November 2017: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/29054508/unknown-antenatal-hiv-infection-status-has-declined-over-time-in-british-columbia-canada
#12
Amy L Slogrove, Julie A Bettinger, Patricia Janssen
OBJECTIVES: The objective was to determine whether the proportion of pregnant women with unknown antenatal HIV-infection status is declining over time in British Columbia (BC) and whether associated factors are amenable to intervention. METHODS: Through a retrospective cohort study of all deliveries in the British Columbia Perinatal Data Registry from 2005 to 2011, we examined the association between year of delivery and no recorded antenatal HIV test result. The trend in unknown antenatal HIV-infection status over time was evaluated by the Cochran-Mantel-Haenzsel test and multivariable logistic regression was used to determine the odds of unknown antenatal HIV-infection status by year of delivery...
October 17, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29048508/characterizing-human-immunodeficiency-virus-antiretroviral-therapy-interruption-and-resulting-disease-progression-using-population-level-data-in-british-columbia-1996-2015
#13
Linwei Wang, Jeong Eun Min, Xiao Zang, Paul Sereda, Richard P Harrigan, Julio S G Montaner, Bohdan Nosyk
Background: Suboptimal retention is among the biggest challenges to realize the full benefits of combination antiretroviral therapy (ART). We aimed to describe ART interruption patterns and identify determinants of disease progression while off ART in British Columbia, Canada. Methods: With population-level data on ART utilization and laboratory testing in British Columbia (1996-2015), we described the timing, frequency, and duration of ART interruptions (a gap of ≥90 days in ART dispensation records)...
October 16, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29046414/early-career-researchers-an-interview-with-jodie-rummer
#14
(no author information available yet)
Jodie Rummer is an Associate Professor at James Cook University, Australia, where she specialises in conservation physiology. She received her Bachelor's degree in Marine Biology and her Master's degree from the University of West Florida, USA. Rummer then moved to the University of British Columbia, Canada, for her PhD in Zoology with Colin Brauner, after which she completed a short postdoc with Dave Randall at the City University of Hong Kong. She has been recognised with a L'Oréal-UNESCO For Women in Science Fellowship and was one of the Australia Broadcasting Corporation's Top Five Scientists under 40 in 2016...
October 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28982836/randomised-clinical-trial-of-cryoballoon-versus-irrigated-radio-frequency-catheter-ablation-for-atrial-fibrillation-the-effect-of-double-short-versus-standard-exposure-cryoablation-duration-during-pulmonary-vein-isolation-circa-dose-methods-and-rationale
#15
Jason G Andrade, Marc W Deyell, Mariano Badra, Jean Champagne, Marc Dubuc, Peter Leong-Sit, Laurent Macle, Paul Novak, Jean-Francois Roux, John Sapp, Anthony Tang, Atul Verma, George A Wells, Paul Khairy
INTRODUCTION: Pulmonary vein isolation (PVI) is an effective therapy for paroxysmal atrial fibrillation (AF), but it has limitations. The two most significant recent advances have centred on the integration of real-time quantitative assessment of catheter contact force into focal radio frequency (RF) ablation catheters and the development of dedicated ablation tools capable of achieving PVI with a single ablation lesion (Arctic Front cryoballoon, Medtronic, Minneapolis, MN, USA). Although each of these holds promise for improving the clinical success of catheter ablation of AF, there has not been a rigorous comparison of these advanced ablation technologies...
October 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28971625/a-welcoming-introduction-to-a-canadian-northwest-coast-thematic-papers-issue
#16
Wayne Vogl
In this commentary, I provide an introduction to and the context for the four articles in the thematic series published to celebrate the Editorial Board Meeting of the Anatomical Record in Vancouver, British Columbia, Canada in July of 2017. The articles describe various aspects of whale anatomy and the potential for a new generation of digital tags to provide information on functional anatomy of free swimming animals in the wild. The whales described are all native to the northwest coast of North America, as well as being found elsewhere, and the authors are related in some way to the University of British Columbia in Vancouver...
November 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28953322/a-historical-review-of-hiv-prevention-and-care-initiatives-in-british-columbia-canada-1996-2015
#17
Michelle Olding, Ben Enns, Dimitra Panagiotoglou, Jean Shoveller, P Richard Harrigan, Rolando Barrios, Thomas Kerr, Julio S G Montaner, Bohdan Nosyk
INTRODUCTION: British Columbia has made significant progress in the treatment and prevention of HIV since 1996, when Highly Active Antiretroviral Therapy (HAART) became available. However, we currently lack a historical summary of HIV prevention and care interventions implemented in the province since the introduction of HAART and how they have shaped the HIV epidemic. Guided by a socio-ecological framework, we present a historical review of biomedical and health services, community and structural interventions implemented in British Columbia from 1996-2015 to prevent HIV transmission or otherwise enhance the cascade of HIV care...
September 19, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28941065/an-economic-model-of-professional-doula-support-in-labor-in-british-columbia-canada
#18
Gillian E Hanley, Lily Lee
INTRODUCTION: Spending on care in childbirth represents a sizable portion of health care budgets. This has engendered a growing interest in potential clinical tools that could be used to improve patient experience and population health at a lower cost. A possible such tool is continuous support in labor from a trained doula, as doula care can decrease the likelihood of cesarean birth, epidural analgesia, and assisted vaginal birth. In addition, there is some emerging evidence suggesting that involving doulas in prenatal care can reduce rates of preterm birth...
September 20, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28882920/the-hat-trick-programme-for-improving-physical-activity-healthy-eating-and-connectedness-among-overweight-inactive-men-study-protocol-of-a-pragmatic-feasibility-trial
#19
Cristina M Caperchione, Joan L Bottorff, John L Oliffe, Steven T Johnson, Kate Hunt, Paul Sharp, Kayla M Fitzpatrick, Ryley Price, S Larry Goldenberg
INTRODUCTION: Physical activity, healthy eating and maintaining a healthy weight are associated with reduced risk of cardiovascular disease, type 2 diabetes and cancer and with improved mental health. Despite these benefits, many men do not meet recommended physical activity guidelines and have poor eating behaviours. Many health promotion programmes hold little appeal to men and consequently fail to influence men's health practices. HAT TRICK was designed as a 12-week face-to-face, gender-sensitised intervention for overweight and inactive men focusing on physical activity, healthy eating and social connectedness and was delivered in collaboration with a major junior Canadian ice hockey team (age range 16-20 years)...
September 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28855256/from-masochistic-enzymology-to-mechanistic-physiology-and-disease
#20
Dennis E Vance
The pioneering work of Eugene Kennedy in the 1950s established the choline pathway for phosphatidylcholine (PC) biosynthesis. However, the regulation of PC biosynthesis was poorly understood at that time. When I started my lab at the University of British Columbia in the 1970s, this was the focus of my research. This article provides my reflections on these studies that began with enzymology and the use of cultured mammalian cells, and progressed to utilize the techniques of molecular biology and gene-targeted mice...
October 20, 2017: Journal of Biological Chemistry
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