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https://www.readbyqxmd.com/read/29200837/the-relationship-of-ssri-and-snri-usage-with-interstitial-lung-disease-and-bronchiectasis-in-an-elderly-population-a-case-control-study
#1
Ted Rosenberg, Rory Lattimer, Patrick Montgomery, Christian Wiens, Liran Levy
Background: The association between interstitial lung disease (ILD) and selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors (SSRI/SNRI) has been previously described in published case reports. However, its prevalence may be more common than expected. We examined the association between SSRI/SNRI usage and presence of ILD and or bronchiectasis (ILD/B) in an elderly population. Methods: We conducted a retrospective case series and case-control study involving all 296 eligible elderly patients in one primary care geriatric practice in Victoria, BC, Canada...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29184379/neurotransmitters-and-sodium-channelopathies-possible-link
#2
COMMENT
Michael F Hammer, Alejandra D C Encinas
Investigators from the University of British Columbia, Great Ormond Street Hospital for Children, and the National Hospital reported their findings on neurotransmitter deficiencies in two patients with mutations in voltage-gated sodium genes (SCN2A and SCN8A) discovered by whole exome sequencing.
November 2017: Pediatric Neurology Briefs
https://www.readbyqxmd.com/read/29120104/ethnicity-and-effectively-maintained-inequality-in-bc-universities
#3
Robert Sweet, Karen Robson, Maria Adamuti-Trache
As Canadian postsecondary systems have expanded they have become more institutionally differentiated. In British Columbia, distinctions are made between research-intensive universities (RIUs) and teaching-intensive universities with respect to resources, programming, and perceived prestige value. We employ an effectively maintained inequality framework to examine the role played by ethnicity in the competition for admission to RIUs. Our findings indicate that, together with socioeconomic status and gender, ethnicity is significantly related to RIU attendance rates...
November 2017: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/29054508/unknown-antenatal-hiv-infection-status-has-declined-over-time-in-british-columbia-canada
#4
Amy L Slogrove, Julie A Bettinger, Patricia Janssen
OBJECTIVES: The objective was to determine whether the proportion of pregnant women with unknown antenatal HIV-infection status is declining over time in British Columbia (BC) and whether associated factors are amenable to intervention. METHODS: Through a retrospective cohort study of all deliveries in the British Columbia Perinatal Data Registry from 2005 to 2011, we examined the association between year of delivery and no recorded antenatal HIV test result. The trend in unknown antenatal HIV-infection status over time was evaluated by the Cochran-Mantel-Haenzsel test and multivariable logistic regression was used to determine the odds of unknown antenatal HIV-infection status by year of delivery...
October 17, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29048508/characterizing-human-immunodeficiency-virus-antiretroviral-therapy-interruption-and-resulting-disease-progression-using-population-level-data-in-british-columbia-1996-2015
#5
Linwei Wang, Jeong Eun Min, Xiao Zang, Paul Sereda, Richard P Harrigan, Julio S G Montaner, Bohdan Nosyk
Background: Suboptimal retention is among the biggest challenges to realize the full benefits of combination antiretroviral therapy (ART). We aimed to describe ART interruption patterns and identify determinants of disease progression while off ART in British Columbia, Canada. Methods: With population-level data on ART utilization and laboratory testing in British Columbia (1996-2015), we described the timing, frequency, and duration of ART interruptions (a gap of ≥90 days in ART dispensation records)...
October 16, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29046414/early-career-researchers-an-interview-with-jodie-rummer
#6
(no author information available yet)
Jodie Rummer is an Associate Professor at James Cook University, Australia, where she specialises in conservation physiology. She received her Bachelor's degree in Marine Biology and her Master's degree from the University of West Florida, USA. Rummer then moved to the University of British Columbia, Canada, for her PhD in Zoology with Colin Brauner, after which she completed a short postdoc with Dave Randall at the City University of Hong Kong. She has been recognised with a L'Oréal-UNESCO For Women in Science Fellowship and was one of the Australia Broadcasting Corporation's Top Five Scientists under 40 in 2016...
October 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28982836/randomised-clinical-trial-of-cryoballoon-versus-irrigated-radio-frequency-catheter-ablation-for-atrial-fibrillation-the-effect-of-double-short-versus-standard-exposure-cryoablation-duration-during-pulmonary-vein-isolation-circa-dose-methods-and-rationale
#7
Jason G Andrade, Marc W Deyell, Mariano Badra, Jean Champagne, Marc Dubuc, Peter Leong-Sit, Laurent Macle, Paul Novak, Jean-Francois Roux, John Sapp, Anthony Tang, Atul Verma, George A Wells, Paul Khairy
INTRODUCTION: Pulmonary vein isolation (PVI) is an effective therapy for paroxysmal atrial fibrillation (AF), but it has limitations. The two most significant recent advances have centred on the integration of real-time quantitative assessment of catheter contact force into focal radio frequency (RF) ablation catheters and the development of dedicated ablation tools capable of achieving PVI with a single ablation lesion (Arctic Front cryoballoon, Medtronic, Minneapolis, MN, USA). Although each of these holds promise for improving the clinical success of catheter ablation of AF, there has not been a rigorous comparison of these advanced ablation technologies...
October 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28971625/a-welcoming-introduction-to-a-canadian-northwest-coast-thematic-papers-issue
#8
Wayne Vogl
In this commentary, I provide an introduction to and the context for the four articles in the thematic series published to celebrate the Editorial Board Meeting of the Anatomical Record in Vancouver, British Columbia, Canada in July of 2017. The articles describe various aspects of whale anatomy and the potential for a new generation of digital tags to provide information on functional anatomy of free swimming animals in the wild. The whales described are all native to the northwest coast of North America, as well as being found elsewhere, and the authors are related in some way to the University of British Columbia in Vancouver...
November 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28953322/a-historical-review-of-hiv-prevention-and-care-initiatives-in-british-columbia-canada-1996-2015
#9
Michelle Olding, Ben Enns, Dimitra Panagiotoglou, Jean Shoveller, P Richard Harrigan, Rolando Barrios, Thomas Kerr, Julio S G Montaner, Bohdan Nosyk
INTRODUCTION: British Columbia has made significant progress in the treatment and prevention of HIV since 1996, when Highly Active Antiretroviral Therapy (HAART) became available. However, we currently lack a historical summary of HIV prevention and care interventions implemented in the province since the introduction of HAART and how they have shaped the HIV epidemic. Guided by a socio-ecological framework, we present a historical review of biomedical and health services, community and structural interventions implemented in British Columbia from 1996-2015 to prevent HIV transmission or otherwise enhance the cascade of HIV care...
September 19, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28941065/an-economic-model-of-professional-doula-support-in-labor-in-british-columbia-canada
#10
Gillian E Hanley, Lily Lee
INTRODUCTION: Spending on care in childbirth represents a sizable portion of health care budgets. This has engendered a growing interest in potential clinical tools that could be used to improve patient experience and population health at a lower cost. A possible such tool is continuous support in labor from a trained doula, as doula care can decrease the likelihood of cesarean birth, epidural analgesia, and assisted vaginal birth. In addition, there is some emerging evidence suggesting that involving doulas in prenatal care can reduce rates of preterm birth...
September 20, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28882920/the-hat-trick-programme-for-improving-physical-activity-healthy-eating-and-connectedness-among-overweight-inactive-men-study-protocol-of-a-pragmatic-feasibility-trial
#11
Cristina M Caperchione, Joan L Bottorff, John L Oliffe, Steven T Johnson, Kate Hunt, Paul Sharp, Kayla M Fitzpatrick, Ryley Price, S Larry Goldenberg
INTRODUCTION: Physical activity, healthy eating and maintaining a healthy weight are associated with reduced risk of cardiovascular disease, type 2 diabetes and cancer and with improved mental health. Despite these benefits, many men do not meet recommended physical activity guidelines and have poor eating behaviours. Many health promotion programmes hold little appeal to men and consequently fail to influence men's health practices. HAT TRICK was designed as a 12-week face-to-face, gender-sensitised intervention for overweight and inactive men focusing on physical activity, healthy eating and social connectedness and was delivered in collaboration with a major junior Canadian ice hockey team (age range 16-20 years)...
September 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28855256/from-masochistic-enzymology-to-mechanistic-physiology-and-disease
#12
Dennis E Vance
The pioneering work of Eugene Kennedy in the 1950s established the choline pathway for phosphatidylcholine (PC) biosynthesis. However, the regulation of PC biosynthesis was poorly understood at that time. When I started my lab at the University of British Columbia in the 1970s, this was the focus of my research. This article provides my reflections on these studies that began with enzymology and the use of cultured mammalian cells, and progressed to utilize the techniques of molecular biology and gene-targeted mice...
October 20, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28841707/a-qualitative-study-of-the-knowledge-attitudes-and-behaviors-of-people-exposed-to-diesel-exhaust-at-the-workplace-in-british-columbia-canada
#13
Mandy Pui, Anne-Marie Nicol, Michael Brauer, Farshad Palad, Christopher Carlsten
PURPOSE: To identify exposure-related knowledge, attitudes and behaviors of individuals occupationally exposed to diesel exhaust (DE); to reveal strengths, knowledge gaps and misperceptions therein. METHODS: A Mental Models approach was used to gather information about current scientific understanding of DE exposure hazards and the ways in which exposure can be reduced. Thirty individuals in British Columbia who were regularly exposed to occupational DE were interviewed...
2017: PloS One
https://www.readbyqxmd.com/read/28816552/the-role-of-biopsy-in-lacrimal-gland-inflammation-a-clinicopathologic-study
#14
Panitee Luemsamran, Jack Rootman, Valerie A White, Nariman Nassiri, Manraj K S Heran
PURPOSE: To determine the causes of lacrimal gland inflammation based on histopathology and systemic evaluation. METHODS: This is a retrospective case series study. From the University of British Columbia Orbit Clinic between January 1976 and December 2008, we reviewed the medical records of 60 patients who presented with inflammatory features of the lacrimal gland (i.e., erythema, edema, or tenderness) in which the diagnoses were not possible clinically and on imaging alone...
August 17, 2017: Orbit
https://www.readbyqxmd.com/read/28814607/early-career-researchers-an-interview-with-graham-scott
#15
(no author information available yet)
Graham Scott is an Assistant Professor at McMaster University, Canada, where he studies the integrative biology of how animals cope in challenging environments. He received his Bachelor's degree in biology before completing a Master's degree with Trish Schulte and then a PhD in 2009 with Bill Milsom at the University of British Columbia, Canada. He moved on to continue his postdoc training with Ian Johnston at the University of St Andrews, UK. Scott received the Animal Section Presidents' Medal from the Society for Experimental Biology in 2012, he was an author on the Journal of Zoology Paper of the Year in 2015 and he was awarded the Robert G...
August 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28789649/intentional-injury-among-the-indigenous-and-total-populations-in-british-columbia-canada-trends-over-time-and-ecological-analyses-of-risk
#16
M Anne George, Andrew Jin, Mariana Brussoni, Christopher E Lalonde, Rod McCormick
BACKGROUND: Our objective was to explore intentional injury disparity between Indigenous populations and the total population in the province of British Columbia (BC), Canada. We focus on hospitalizations, including both self-inflicted injuries and injuries inflicted by others. METHODS: We used data from BC's universal health care insurance plan, 1991 to 2010, linked to Vital Statistics databases. Indigenous people were identified through the insurance premium group, and birth and death records...
August 8, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28747313/long-term-complications-reoperations-and-survival-following-cardioverter-defibrillator-implant
#17
Nathaniel Mark Hawkins, Maja Grubisic, Jason G Andrade, Flora Huang, Lillian Ding, Min Gao, Jamil Bashir
OBJECTIVE: Implantable cardioverter-defibrillators (ICDs) reduce risk of death in select populations, but are also associated with harms. We aimed to characterise long-term complications and reoperation rate. METHODS: We assessed the rate, cumulative incidence and predictors of long-term reoperation and survival using a prospective, multicentre registry serving British Columbia in Canada, a universal single payer healthcare system with 4.5 million residents. 3410 patients (mean 63...
July 26, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28724699/early-career-researchers-an-interview-with-jeremy-goldbogen
#18
(no author information available yet)
Jeremy Goldbogen is an Assistant Professor at the Hopkins Marine Station, Stanford University, USA, where he studies the integrative biology of vertebrate filter feeders from forage fish to baleen whales. He received his Bachelor's degree in Zoology from the University of Texas, Austin, USA, before moving to the Scripps Institution of Oceanography and then the University of British Columbia for his PhD, which he completed in 2010 in the laboratory of Bob Shadwick. After a short postdoc at Scripps, Goldbogen moved to continue his postdoc training at the Cascadia Research Collective in Olympia, Washington...
July 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28668930/cell-scientist-to-watch-jacky-goetz
#19
(no author information available yet)
Jacky Goetz graduated in pharmacology and cell biology from the University of Strasbourg in France and moved to Canada to the laboratory of Ivan Robert Nabi at the University of Montreal and later the University of British Columbia, to work on the interaction between the endoplasmic reticulum and mitochondria, as well as the glycosylation of membrane proteins. In 2007, he received his PhD from both the University of Montreal and the University of Strasbourg. For his postdoc, Jacky moved to the Spanish national centre for cardiovascular research (CNIC) in Madrid and the laboratory of Miguel Angel del Pozo to study the tumour microenvironment...
July 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28661887/getting-by-with-a-little-help-from-friends-and-colleagues-testing-how-residents-social-support-networks-affect-loneliness-and-burnout
#20
Eamonn Rogers, Andrea N Polonijo, Richard M Carpiano
OBJECTIVE: To determine how residents' relationships with their sources of social support (ie, family, friends, and colleagues) affect levels of burnout and loneliness. DESIGN: Cross-sectional survey. SETTING: Faculty of Medicine at the University of British Columbia in Vancouver. PARTICIPANTS: A total of 198 physician-trainees in the university's postgraduate medical education program. MAIN OUTCOME MEASURES: Residents' personal and work-related burnout scores (measured using items from the Copenhagen Burnout Inventory); loneliness (measured using a 3-item loneliness scale); and social support (assessed with the Lubben Social Network Scale, version 6)...
November 2016: Canadian Family Physician Médecin de Famille Canadien
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