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https://www.readbyqxmd.com/read/28302424/external-validation-of-the-universal-termination-of-resuscitation-rule-for-out-of-hospital-cardiac-arrest-in-british-columbia
#1
Brian Grunau, John Taylor, Frank X Scheuermeyer, Robert Stenstrom, William Dick, Takahisa Kawano, David Barbic, Ian Drennan, Jim Christenson
STUDY OBJECTIVE: The Universal Termination of Resuscitation Rule (TOR Rule) was developed to identify out-of-hospital cardiac arrests eligible for field termination of resuscitation, avoiding futile transportation to the hospital. The validity of the rule in emergency medical services (EMS) systems that do not routinely transport out-of-hospital cardiac arrest patients to the hospital is unknown. We seek to validate the TOR Rule in British Columbia. METHODS: This study included consecutive, nontraumatic, adult, out-of-hospital cardiac arrests treated by EMS in British Columbia from April 2011 to September 2015...
March 14, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28283098/from-bugs-to-brains-the-microbiome-in-neurological-health
#2
EDITORIAL
Kyla A McKay, Kaarina Kowalec, Fiona Brinkman, B Brett Finlay, Marc Horwitz, Amee R Manges, Lisa Osborne, Helen Tremlett
Knowledge surrounding the trillions of microbes that inhabit the human gut has bloomed exponentially in recent years, and the emerging concept of a gut-brain axis represents a major shift in how we think about neurological health. A recent workshop at the University of British Columbia, Canada brought together multi-disciplinary leaders in the field of microbiomics and brain health and aimed to serve as a springboard for future combined endeavors in these areas. This article provides the motivation for, and overview of, the workshop, and the next steps in establishing a cross-disciplinary initiative on Brain Health and the Microbiome...
February 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28278712/nonrandom-occurrence-of-lymphoid-cancer-types-in-140-families
#3
Samantha J Jones, Jackson Voong, Ruth Thomas, Amy English, Johanna Schuetz, Graham W Slack, Jinko Graham, Joseph M Connors, Angela Brooks-Wilson
We studied 140 families with two or more lymphoid cancers, including non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), chronic lymphocytic leukemia (CLL), and multiple myeloma (MM), for deviation from the population age of onset and lymphoid cancer co-occurrence patterns. Median familial NHL, HL, CLL and MM ages of onset are substantially earlier than comparable population data. NHL, HL and CLL (but not MM) also show earlier age of onset in later generations, known as anticipation. The co-occurrence of lymphoid cancers is significantly different from that expected based on population frequencies (p < ...
February 21, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28252376/challenging-key-assumptions-embedded-in-health-canada-s-cigarette-packaging-legislation-findings-from-in-situ-interviews-with-smokers-in-vancouver
#4
Rebecca J Haines-Saah, Kirsten Bell
OBJECTIVES: The main objective of this study was to utilize qualitative research methods in order to explore variations in how smokers respond to the government-mandated graphic health warnings and messages on their cigarette packets. METHODS: Sixty in situ interviews were carried out with people while they were smoking in public settings across the city of Vancouver, British Columbia. During the interviews, participants were asked to recall the warning label on their cigarette packet, and general questions about the effects the imagery and text have had on their smoking...
March 1, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28220681/canadian-university-acknowledgment-of-indigenous-lands-treaties-and-peoples
#5
Rima Wilkes, Aaron Duong, Linc Kesler, Howard Ramos
At many Canadian universities it is now common to publicly acknowledge Indigenous lands, treaties, and peoples. Yet, this practice has yet to be considered as a subject of scholarly inquiry. How does this practice vary and why? In this paper we describe the content and practice of acknowledgment, linking this content to treaty relationships (or lack thereof). We show that acknowledgment tends to be one of five general types: of land and title (British Columbia), of specific treaties and political relationships (Prairies), of multiculturalism and heterogeneity (Ontario), of no practice (most of Quebec), and of people, territory, and openness to doing more (Atlantic)...
February 2017: Canadian Review of Sociology, Revue Canadienne de Sociologie
https://www.readbyqxmd.com/read/28180957/different-responses-of-influenza-epidemic-to-weather-factors-among-shanghai-hong-kong-and-british-columbia
#6
Xi-Ling Wang, Lin Yang, Dai-Hai He, Alice Py Chiu, Kwok-Hung Chan, King-Pan Chan, Maigeng Zhou, Chit-Ming Wong, Qing Guo, Wenbiao Hu
Weather factors have long been considered as key sources for regional heterogeneity of influenza seasonal patterns. As influenza peaks coincide with both high and low temperature in subtropical cities, weather factors may nonlinearly or interactively affect influenza activity. This study aims to assess the nonlinear and interactive effects of weather factors with influenza activity and compare the responses of influenza epidemic to weather factors in two subtropical regions of southern China (Shanghai and Hong Kong) and one temperate province of Canada (British Columbia)...
February 8, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28145960/the-2016-austrian-swiss-german-fellowship
#7
Andrea N Veljkovic, Mathew D Sewell, Simon C Mears, Eric W Edmonds
The Austrian-Swiss-German (ASG) Traveling Fellowship, which began in 1979, is an annual exchange of surgeons between the German-speaking countries of Austria, Switzerland, and Germany and the English-speaking countries of the United States, England, and Canada. In 2016, 4 fellows were chosen to participate in the fellowship, including Eric Edmonds from the University of California, San Diego; Simon Mears from the University of Arkansas for Medical Sciences; Mathew Sewell from the James Cook University in Middlesbrough, England; and Andrea Veljkovic from the University of British Columbia in Vancouver...
February 1, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28095829/a-middle-eastern-journey-of-integrating-interprofessional-education-into-the-healthcare-curriculum-a-swoc-analysis
#8
Alla El-Awaisi, Kyle John Wilby, Kerry Wilbur, Maguy Saffouh El Hajj, Ahmed Awaisu, Bridget Paravattil
BACKGROUND: Interprofessional education (IPE) is an emerging concept in the Middle East with a number of health professional degree programs continually striving to meet international accreditation requirements to enhance the quality of education and ensure high standards are maintained. Using the College of Pharmacy at Qatar University (CPH QU) as a model, this article describes the IPE initiatives coordinated through the College's IPE Committee, with representation from fourteen programs at four Healthcare institutions: Qatar University; Weill Cornell Medical College in Qatar; the University of Calgary in Qatar; and the College of North Atlantic in Qatar...
January 17, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28050654/misalignments-of-purpose-and-power-in-an-early-canadian-interprofessional-education-initiative
#9
Sarah Whyte, Elise Paradis, Carrie Cartmill, Ayelet Kuper, Heather Boon, Corinne Hart, Saleem Razack, Mandy Pipher, Cynthia R Whitehead
Interprofessional education (IPE) has been widely incorporated into health professional curricula and accreditation standards despite an arguably thin base of evidence regarding its clinical effects, theoretical underpinnings, and social implications. To better understand how and why IPE first took root, but failed to grow, this study examines one of the earliest documented IPE initiatives, which took place at the University of British Columbia between 1960 and 1975. We examined a subset of 110 texts (academic literature, grey literature, and unpublished records) from a larger study that uses Critical Discourse Analysis to trace the emergence of IPE in Canada...
January 3, 2017: Advances in Health Sciences Education: Theory and Practice
https://www.readbyqxmd.com/read/28031950/improving-public-awareness-and-outcomes-for-oral-cancer
#10
Catherine F Poh
Catherine Poh speaks to G Westcott, Commissioning Editor: Dr. C Poh gained a dental degree from the National Taiwan University in Taipei, Taiwan and went on to gain her PhD from the University of British Columbia in 1997, looking into molecular biology in oral cancer. In addition to her current role an associate professor in the Faculty of Dentistry at the University of British Columbia, she is a senior clinician scientist at the Integrative Oncology Department of the BC Cancer Agency's Research Centre. She has various other roles, including being active within the Oral Oncology Department at BC Cancer Agency and the Oral Mucosal Disease Program at Vancouver General Hospital...
March 2016: Future Science OA
https://www.readbyqxmd.com/read/28002072/the-100-top-cited-articles-in-pulmonary-imaging-a-bibliometric-analysis
#11
Su Jin Hong, Kyoung Ja Lim, Hye Jeon Hwang, Sora Baek, Young Lan Seo, Eun Joo Yun, Chul Soon Choi, Dae Young Yoon
PURPOSE: The purpose of this study was to identify and characterize the 100 top-cited articles in pulmonary imaging. MATERIALS AND METHODS: From the database of Journal Citation Reports, 274 journals whose scope included pulmonary imaging were selected. The Web of Science search tools were then used to identify the 100 top-cited articles in the subject of pulmonary imaging published in these journals. The parameters used to analyze the characteristics of the 100 top-cited articles were journal (including subject category and impact factor), publication year, number of citations and annual citations, department and institution of authors, country of origin, article type, imaging technique, and topic...
December 19, 2016: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/27993329/an-mrna-gene-expression-based-signature-to-identify-fgfr1-amplified-estrogen-receptor-positive-breast-tumors
#12
Jingqin Luo, Shuzhen Liu, Samuel Leung, Alejandro A Gru, Yu Tao, Jeremy Hoog, Julie Ho, Sherri R Davies, D Craig Allred, Andrea L Salavaggione, Jacqueline Snider, Elaine R Mardis, Torsten O Nielsen, Matthew J Ellis
Fibroblast growth factor receptor 1 (FGFR1) amplification drives poor prognosis and is an emerging therapeutic target. We sought to construct a multigene mRNA expression signature to efficiently identify FGFR1-amplified estrogen receptor-positive (ER(+)) breast tumors. Five independent breast tumor series were analyzed. Genes discriminative for FGFR1 amplification were screened transcriptome-wide by receiver operating characteristic analyses. The METABRIC series was leveraged to construct/evaluate four approaches to signature composition...
January 2017: Journal of Molecular Diagnostics: JMD
https://www.readbyqxmd.com/read/27888179/predicting-tuberculosis-risk-in-the-foreign-born-population-of-british-columbia-canada-study-protocol-for-a-retrospective-population-based-cohort-study
#13
Lisa A Ronald, Jonathon R Campbell, Robert F Balshaw, David Z Roth, Kamila Romanowski, Fawziah Marra, Victoria J Cook, James C Johnston
INTRODUCTION: Improved understanding of risk factors for developing active tuberculosis (TB) will better inform decisions about diagnostic testing and treatment for latent TB infection (LTBI) in migrant populations in low-incidence regions. We aim to examine TB risk factors among the foreign-born population in British Columbia (BC), Canada, and to create and validate a clinically relevant multivariate risk score to predict active TB. METHODS AND ANALYSIS: This retrospective population-based cohort study will include all foreign-born individuals who acquired permanent resident status in Canada between 1 January 1985 and 31 December 2013 and acquired healthcare coverage in BC at any point during this period...
November 25, 2016: BMJ Open
https://www.readbyqxmd.com/read/27847352/the-effects-of-an-e-mental-health-program-and-job-coaching-on-the-risk-of-major-depression-and-productivity-in-canadian-male-workers-protocol-for-a-randomized-controlled-trial
#14
JianLi Wang, Scott B Patten, Raymond W Lam, Mark Attridge, Kendall Ho, Norbert Schmitz, Alain Marchand, Bonnie M Lashewicz
BACKGROUND: Major depression (MDE) is prevalent in men and affects men's health and productivity. Because of the stigma against depression and social/gender norms, men are less likely to seek help for emotion and stress-related issues. Therefore, innovative solutions tailored for men are needed. With rapid development of the Internet and information technologies, one promising solution that has drawn considerable attentions is electronic mental (e-mental) health programs and services...
November 15, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27818988/academic-outcomes-and-utility-of-gastroenterology-residents-in-training-course-abstract-presentations-the-university-of-british-columbia-experience
#15
Faisal Al Shatti, Vladimir Marquez Azalagara, Eric M Yoshida
No abstract text is available yet for this article.
2016: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27817792/modelling-disease-progression-in-relapsing-remitting-onset-multiple-sclerosis-using-multilevel-models-applied-to-longitudinal-data-from-two-natural-history-cohorts-and-one-treated-cohort
#16
Kate Tilling, Michael Lawton, Neil Robertson, Helen Tremlett, Feng Zhu, Katharine Harding, Joel Oger, Yoav Ben-Shlomo
BACKGROUND: The ability to better predict disease progression represents a major unmet need in multiple sclerosis (MS), and would help to inform therapeutic and management choices. OBJECTIVES: To develop multilevel models using longitudinal data on disease progression in patients with relapsing-remitting MS (RRMS) or secondary-progressive MS (SPMS); and to use these models to estimate the association of disease-modifying therapy (DMT) with progression. DESIGN: Secondary analysis of three MS cohorts...
October 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27810759/microbial-quality-of-reclaimed-water-for-urban-reuses-probabilistic-risk-based-investigation-and-recommendations
#17
Gyan Chhipi-Shrestha, Kasun Hewage, Rehan Sadiq
Although Canada has abundant freshwater resources, many cities still experience seasonal water shortage. Supply-side and demand-side management is a core strategy to address this water shortage. Under this strategy, reclaimed water, which the Canadian public is willing to use for non-potable purposes, is an option. However, no universal guidelines exist for reclaimed water use. Despite the federal government's long-term goal to develop guidelines for many water reuse applications, guidelines have only been prescribed for reclaimed water use in toilet and urinal flushing in Canada...
January 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27780338/a-longitudinal-study-of-the-relationships-between-mood-symptoms-body-mass-index-and-serum-adipokines-in-bipolar-disorder
#18
David J Bond, Ana C Andreazza, John Hughes, Taj Dhanoa, Ivan J Torres, Jan-Marie Kozicky, L Trevor Young, Raymond W Lam, Lakshmi N Yatham
OBJECTIVE: There is a bidirectional relationship between obesity and mood disorders, with each increasing the risk of developing the other. This relationship suggests that they have overlapping pathophysiologic mechanisms. Adipose tissue-derived hormones, or adipokines, regulate appetite and metabolism and have activity in limbic brain regions, making them potential shared etiologic factors between elevated body mass index (BMI) and mood disorders. However, the precise relationships between BMI, mood, and adipokines are unknown...
October 25, 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27756294/measuring-interprofessional-competencies-and-attitudes-among-health-professional-students-creating-family-planning-virtual-patient-cases
#19
Eric Wong, Jasmine J Leslie, Judith A Soon, Wendy V Norman
BACKGROUND: The Virtual Interprofessional Patients-Computer-Assisted Reproductive Health Education for Students (VIP-CARES) Project took place during the summers of 2010-2012 for eight weeks each year at the University of British Columbia (UBC). Undergraduate health care students worked collaboratively to develop virtual patient case-based learning modules on the topic of family planning. The purpose of this study was to evaluate the changes in perception towards interprofessional collaboration (IPC) among the participants, before and after the project...
October 19, 2016: BMC Medical Education
https://www.readbyqxmd.com/read/27731337/production-of-valuable-compounds-by-molds-and-yeasts
#20
Arnold L Demain, Evan Martens
We are pleased to dedicate this paper to Dr Julian E Davies. Julian is a giant among microbial biochemists. He began his professional career as an organic chemistry PhD student at Nottingham University, moved on to a postdoctoral fellowship at Columbia University, then became a lecturer at the University of Manchester, followed by a fellowship in microbial biochemistry at Harvard Medical School. In 1965, he studied genetics at the Pasteur Institute, and 2 years later joined the University of Wisconsin in the Department of Biochemistry...
October 12, 2016: Journal of Antibiotics
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