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https://www.readbyqxmd.com/read/29161045/principles-around-accurate-blood-volume-collection-using-capillary-action
#1
Florian Lapierre, Andrew A Gooley, Michael Breadmore
Capillary action is one mechanism microfluidics uses to draw liquid autonomously in a substrate without the need of external energy. This behaviour can be exploited to collect accurate volumes of liquids such as blood in narrow columns known as capillaries and help the development of inexpensive, user-friendly personalised biomedical tools. Precision bore glass capillaries demonstrate the 'state of the art' for volume accuracy and precision but dimension of height and radius must be carefully chosen in order to exploit the capillary action behaviour efficiently...
November 21, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29160640/thoracoscopic-repair-of-congenital-diaphragmatic-hernia-review-of-the-results
#2
Catarina Barroso, Jorge Correia-Pinto
Congenital diaphragmatic hernia (CDH) remains one of the major challenges in neonatal surgery. Survival rate has increased in the last decades mainly due to perinatal care and surgical technique improvements. Classically, a laparotomy has been performed after cardiovascular and respiratory stabilization. Introduction of thoracoscopy in the repair of CDH brought the known advantages of reduced postoperative pain and better cosmesis. However, its safety and effectiveness have been questioned in the last few years...
November 21, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/29159773/japan-society-of-gynecologic-oncology-guidelines-2015-for-the-treatment-of-vulvar-cancer-and-vaginal-cancer
#3
Toshiaki Saito, Tsutomu Tabata, Hitoshi Ikushima, Hiroyuki Yanai, Hironori Tashiro, Hitoshi Niikura, Takeo Minaguchi, Toshinari Muramatsu, Tsukasa Baba, Wataru Yamagami, Kazuya Ariyoshi, Kimio Ushijima, Mikio Mikami, Satoru Nagase, Masanori Kaneuchi, Nobuo Yaegashi, Yasuhiro Udagawa, Hidetaka Katabuchi
BACKGROUND: Vulvar cancer and vaginal cancer are relatively rare tumors, and there had been no established treatment principles or guidelines to treat these rare tumors in Japan. The first version of the Japan Society of Gynecologic Oncology (JSGO) guidelines for the treatment of vulvar cancer and vaginal cancer was published in 2015 in Japanese. OBJECTIVE: The JSGO committee decided to publish the English version of the JSGO guidelines worldwide, and hope it will be a useful guide to physicians in a similar situation as in Japan...
November 20, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29158952/the-impact-of-attentional-focus-on-the-treatment-of-musculoskeletal-and-movement-disorders
#4
Christopher Hunt, Arsenio Paez, Eric Folmar
Treatment plans employed by physical therapists involved in musculoskeletal rehabilitation may follow a conventional medical-model approach, isolating care at the tissue level but neglecting consideration for neurocognitive contributions to recovery. Understanding and integration of motor learning concepts into physical therapy practice is integral for influencing the human movement system in the most effective manner. One such motor learning concept is the use of verbal instruction to influence the attentional focus of the learner...
November 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/29158011/extended-adjuvant-intermittent-letrozole-versus-continuous-letrozole-in-postmenopausal-women-with-breast-cancer-sole-a-multicentre-open-label-randomised-phase-3-trial
#5
Marco Colleoni, Weixiu Luo, Per Karlsson, Jacquie Chirgwin, Stefan Aebi, Guy Jerusalem, Patrick Neven, Erika Hitre, Marie-Pascale Graas, Edda Simoncini, Claus Kamby, Alastair Thompson, Sibylle Loibl, Joaquín Gavilá, Katsumasa Kuroi, Christian Marth, Bettina Müller, Seamus O'Reilly, Vincenzo Di Lauro, Andrea Gombos, Thomas Ruhstaller, Harold Burstein, Karin Ribi, Jürg Bernhard, Giuseppe Viale, Rudolf Maibach, Manuela Rabaglio-Poretti, Richard D Gelber, Alan S Coates, Angelo Di Leo, Meredith M Regan, Aron Goldhirsch
BACKGROUND: In animal models of breast cancer, resistance to continuous use of letrozole can be reversed by withdrawal and reintroduction of letrozole. We therefore hypothesised that extended intermittent use of adjuvant letrozole would improve breast cancer outcome compared with continuous use of letrozole in postmenopausal women. METHODS: We did the multicentre, open-label, randomised, parallel, phase 3 SOLE trial in 240 centres (academic, primary, secondary, and tertiary care centres) in 22 countries...
November 17, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/29157253/the-no-correlation-argument-can-the-morality-of-conscientious-objection-be-empirically-supported-the-italian-case
#6
Marco Bo, Carla Maria Zotti, Lorena Charrier
BACKGROUND: The legitimacy of conscientious objection to abortion continues to fuel heated debate in Italy. In two recent decisions, the European Committee for Social Rights underlined that conscientious objection places safe, legal, and accessible care and services out of reach for most Italian women and that the measures that Italy has adopted to guarantee free access to abortion services are inadequate. Nevertheless, the Ministry of Health states that current Italian legislation, if appropriately applied, accommodates both the right to conscientious objection and the right to voluntary abortion...
November 21, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/29157232/implementation-of-an-interprofessional-team-based-learning-program-involving-seven-undergraduate-health-and-social-care-programs-from-two-universities-and-students-evaluation-of-their-readiness-for-interprofessional-learning
#7
Lap Ki Chan, Fraide Ganotice, Frances Kam Yuet Wong, Chak Sing Lau, Susan M Bridges, Celia Hoi Yan Chan, Namkiu Chan, Phoebe Wing Lam Chan, Hai Yong Chen, Julie Yun Chen, Jody Kwok Pui Chu, Charlene C Ho, Jacqueline Mei Chi Ho, Tai Pong Lam, Veronica Suk Fun Lam, Qingyun Li, Jian Gang Shen, Julian Alexander Tanner, Winnie Wan Yee Tso, Arkers Kwan Ching Wong, Gordon Tin Chun Wong, Janet Yuen Ha Wong, Nai Sum Wong, Alan Worsley, Lei King Yu, Tin Pui Yum
BACKGROUND: Interprofessional learning is gaining momentum in revolutionizing healthcare education. During the academic year 2015/16, seven undergraduate-entry health and social care programs from two universities in Hong Kong took part in an interprofessional education program. Based on considerations such as the large number of students involved and the need to incorporate adult learning principles, team-based learning was adopted as the pedagogy for the program, which was therefore called the interprofessional team-based learning program (IPTBL)...
November 21, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/29157119/biomarker-combinations-for-diagnosis-and-prognosis-in-multicenter-studies-principles-and-methods
#8
Allison Meisner, Chirag R Parikh, Kathleen F Kerr
Many investigators are interested in combining biomarkers to predict a binary outcome or detect underlying disease. This endeavor is complicated by the fact that many biomarker studies involve data from multiple centers. Depending upon the relationship between center, the biomarkers, and the target of prediction, care must be taken when constructing and evaluating combinations of biomarkers. We introduce a taxonomy to describe the role of center and consider how a biomarker combination should be constructed and evaluated...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/29157055/haptotherapy-as-a-new-intervention-for-treating-fear-of-childbirth-a-randomized-controlled-trial
#9
Gert A Klabbers, Klaas Wijma, K Marieke Paarlberg, Wilco H M Emons, Ad J J M Vingerhoets
OBJECTIVE: To evaluate the effect of haptotherapy on severe fear of childbirth in pregnant women. DESIGN: Randomized controlled trial. SETTING: Community midwifery practices and a teaching hospital in the Netherlands. POPULATION OR SAMPLE: Primi- and multigravida, suffering from severe fear of childbirth (N = 134). METHODS: Haptotherapy, psycho-education via Internet and care as usual were randomly assigned at 20-24 weeks of gestation and the effects were compared at 36 weeks of gestation and 6 weeks and 6 months postpartum...
November 20, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29155536/antimicrobial-resistance-and-antibiotic-prescribing-in-dental-practice
#10
Nikolaus O A Palmer
The purpose of this paper is to review the principles of antibiotic prescribing in light of the increasing worldwide problem of antimicrobial resistance and the evidence of inappropriate use of antibiotics in dentistry. Guidance on the management of dental infections and antibiotic prophylaxis based on a review of the scientific evidence will be given to ensure good patient care. Clinical relevance: To discuss the relevance of legislation around antimicrobial prescribing and antimicrobial stewardship for dentists...
December 2016: Dental Update
https://www.readbyqxmd.com/read/29154748/cdc-safety-training-course-for-ebola-virus-disease-healthcare-workers
#11
Rupa Narra, Jeremy Sobel, Catherine Piper, Deborah Gould, Nahid Bhadelia, Mary Dott, Anthony Fiore, William A Fischer, Mary Jo Frawley, Patricia M Griffin, Douglas Hamilton, Barbara Mahon, Satish K Pillai, Emily F Veltus, Robert Tauxe, Michael Jhung
Response to sudden epidemic infectious disease emergencies can demand intensive and specialized training, as demonstrated in 2014 when Ebola virus disease (EVD) rapidly spread throughout West Africa. The medical community quickly became overwhelmed because of limited staff, supplies, and Ebola treatment units (ETUs). Because a mechanism to rapidly increase trained healthcare workers was needed, the US Centers for Disease Control and Prevention developed and implemented an introductory EVD safety training course to prepare US healthcare workers to work in West Africa ETUs...
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29154064/living-with-chronic-pain-evaluating-patient-experiences-with-a-medical-group-visit-focused-on-mindfulness-and-non-pharmacological-strategies
#12
Anna Sophia Lestoquoy, Lance D Laird, Suzanne Mitchell, Katherine Gergen-Barnett, N Lily Negash, Kelly McCue, Racquel Enad, Paula Gardiner
OBJECTIVES: Little is known about the acceptance of non-pharmacological group strategies delivered to low income racially diverse patients with chronic pain and depression. This paper examines how the Integrative Medical Group Visit (IMGV) addresses many of the deficits identified with usual care. DESIGN AND SETTING: Six IMGVs cohorts were held at a safety net hospital and two federally funded community health centres. Data was gathered through focus groups. Transcripts were analysed using both a priori codes and inductive coding...
December 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29153354/the-choosing-wisely-initiative-a-critical-analysis-with-a-special-focus-on-primary-care
#13
Karl Horvath, Andrea Siebenhofer
The Choosing Wisely initiative (CWI), a campaign led by the American Board of Internal Medicine (ABIM) Foundation, promotes doctor-patient communication and reducing waste in healthcare. At present, many of the top 5 lists from the Choosing Wisely Initiative appear to be primarily eminence-based and influenced by self-interest. The implementation of recommendations from these lists may mean taking a step backwards to the time before evidence-based medicine. On the other hand, despite all the challenges that the Choosing Wisely initiatives are currently facing, it is difficult to deny that they also hold great potential in terms of making healthcare systems more efficient and beneficial to patients...
November 15, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/29153052/palliative-care-issues-and-challenges-in-saudi-arabia-knowledge-assessment-among-nursing-students
#14
Omar Mohammad Khraisat, Mahmoud Hamdan, Mohannad Ghazzawwi
BACKGROUND: Nurses are the heart of the palliative care team who provide high standards of care since they spend the longest time with patients. However, lack of adequate knowledge of palliative care is considered as one of the main obstacles to palliative care improvement. AIM: A survey was conducted to assess Saudi nursing students' knowledge about palliative care. METHODS: Using a descriptive design, 154 students who enrolled in first year and who will graduate within 1 year were surveyed in a nursing college located in Riyadh, the capital of Saudi Arabia...
January 1, 2017: Journal of Palliative Care
https://www.readbyqxmd.com/read/29152469/eyebrow-incision-for-surgical-evacuation-of-a-lobar-intracerebral-hematoma-with-a-novel-endoport-system
#15
Dale Ding, Colin J Przybylowski, Robert M Starke, R Webster Crowley, Kenneth C Liu
Large lobar intracerebral hemorrhages (ICHs) can cause rapid neurological deterioration, and affected patients have low rates of survival and functional independence. Currently, the role of surgical intervention in the management patients with lobar ICHs is controversial. Minimally invasive technologies have been developed which may potentially decrease the operative morbidity of ICH surgery. The aim of this case report is to describe the technical aspects of the use of a novel minimally invasive endoport system, the BrainPath (NICO, Indianapolis, IN, USA), through an eyebrow incision for evacuation of a large lobar hematoma...
June 2017: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/29151380/stakeholders-perceptions-of-health-technology-assessment-in-turkey
#16
Kirstin Ozturk, Bilgehan Karadayı, Olgun Şener
BACKGROUND: In April of 2014, the Turkish Ministry of Health held the First Annual Health Technology Assessment (HTA) Meeting in Antalya. OBJECTIVES: The objectives were to understand the perceptions of stakeholders regarding the current status of HTA and document their recommendations and strategies for promoting systematic use of HTA in Turkey. METHODS: The study was conducted using a qualitative written survey assessing current compliance with the fifteen HTA principles suggested by Drummond et al...
November 20, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/29149872/process-quality-of-decision-making-in-multidisciplinary-cancer-team-meetings-a-structured-observational-study
#17
Pola Hahlweg, Sarah Didi, Levente Kriston, Martin Härter, Yvonne Nestoriuc, Isabelle Scholl
BACKGROUND: The quality of decision-making in multidisciplinary team meetings (MDTMs) depends on the quality of information presented and the quality of team processes. Few studies have examined these factors using a standardized approach. The aim of this study was to objectively document the processes involved in decision-making in MDTMs, document the outcomes in terms of whether a treatment recommendation was given (none vs. singular vs. multiple), and to identify factors related to type of treatment recommendation...
November 17, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29149359/-preclinical-and-intrahospital-management-of-mass-casualties-and-terrorist-incidents
#18
REVIEW
A Franke, D Bieler, B Friemert, E Kollig, S Flohe
Due to the recent terrorist attacks in Paris, Brussels, Ansbach, Munich, Berlin and more recently Manchester and London, terrorism is realized as a present threat to our society and social life, as well as a challenge for the health care system. Without fueling anxiety, there is a need for sensitization to this subject and to familiarize all concerned with the special kind of terrorist attack-related injuries, the operational priorities and tactics and the individual basic principles of preclinical and hospital care...
October 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29149126/pharmacogenomics-principles-and-relevance-to-oncology-nursing%C3%A2
#19
Crystal H Dodson
BACKGROUND: Pharmacogenomics is the fastest growing field in precision medicine. Based on current use, oncology encompasses the largest share of the precision medicine market, necessitating that oncology nurses understand the principles of pharmacogenomics and how it affects clinical practice.
. OBJECTIVES: This article will define precision medicine and pharmacogenomics and will provide examples of pharmacogenomic tests, including those associated with tumor markers, and nursing implications...
December 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29147897/vacuum-assisted-wound-closure-with-mesh-mediated-fascial-traction-achieves-better-outcomes-than-vacuum-assisted-wound-closure-alone-a-comparative-study
#20
Giuseppe Salamone, Leo Licari, Giovanni Guercio, Albert Comelli, Mirko Mangiapane, Nicolò Falco, Roberta Tutino, Noemi Bagarella, Sofia Campanella, Calogero Porrello, Roberto Gullo, Gianfranco Cocorullo, Gaspare Gulotta
BACKGROUND: Open abdomen (OA) permits the application of damage control surgery principles when abdominal trauma, sepsis, severe acute peritonitis and abdominal compartmental syndrome (ACS) occur. METHODS: Non-traumatic patients treated with OA between January 2010 and December 2015 were identified in a prospective database, and the data collected were retrospectively reviewed. Patients' records were collected from charts and the surgical and intensive care unit (ICU) registries...
November 16, 2017: World Journal of Surgery
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