keyword
https://read.qxmd.com/read/37700918/green-tea-extract-has-a-protective-effect-on-leptin-and-lipid-profile-levels-due-to-the-induction-of-depot-medroxyprogesterone-acetate
#1
JOURNAL ARTICLE
Endang Sri Wahyuni, Maryatun Maryatun, Nora Veri, Elly Susilawati, Lely Firrahmawati, Endah Sri Wahyuni, Riyani Wulandari
BACKGROUND: Depot medroxyprogesterone acetate (DMPA) is a progesterone derivative synthesized in the laboratory. This substance has the ability to suppress ovulation, induce endometrial shrinkage, and even affect the hypothalamic-pituitary-gonadal axis in the reproductive system. OBJECTIVE: The purpose of this study was to investigate the effects of administration of green tea extract on reducing visceral fat, increasing leptin levels, and improving the lipid profile in female rats injected with depot medroxyprogesterone acetate (DMPA)...
2023: Medical Archives
https://read.qxmd.com/read/37574723/distinct-response-of-adipocyte-progenitors-to-glucocorticoids-determines-visceral-obesity-via-the-tead1-mir-27b-prdm16-axis
#2
JOURNAL ARTICLE
Yifan Lv, Fan Xia, Jing Yu, Yunlu Sheng, Yi Jin, Yanqiang Li, Guoxian Ding
OBJECTIVE: Visceral obesity contributes to obesity-related complications; however, the intrinsic mechanism of depot-specific adipose tissue behavior remains unclear. Despite the pro-adipogenesis role of glucocorticoids (GCs) in adipogenesis, the role of GCs in visceral adiposity rather than in subcutaneous adipose tissue is not established. Because adipocyte progenitors display a striking depot-specific pattern, the regulatory pathways of novel progenitor subtypes within different depots remain unclear...
August 13, 2023: Obesity
https://read.qxmd.com/read/37164744/goishi-tea-leaf-powder-affects-lower-body-weight-and-visceral-fat-accumulation-during-energy-restriction-in-obese-rats
#3
JOURNAL ARTICLE
Takahiro Seura, Tomomi Kanno, Yoshiaki Miyake, Misako Sogawa
Goishi tea is a unique Japanese post-fermented tea produced in Kochi prefecture. The aim of this study was to investigate whether the supplementation of energy-restricted diet with Goishi tea leaves affects body weight, visceral fat accumulation, and fecal lipids in diet-induced obese rats. 18 male Wistar rats were fed a high-fat diet for 12 weeks. Subsequently, the diet-induced obese rats were fed a low-energy diet containing 1% (G1 group) or 3% (G3 group) of Goishi tea leaf powder, or without any tea extracts (C group) for 4 weeks...
2023: Journal of Medical Investigation: JMI
https://read.qxmd.com/read/37111053/relationship-of-the-behavior-of-older-participants-with-body-composition-change-results-of-the-second-wave-of-the-cognition-of-older-people-education-recreational-activities-nutrition-comorbidities-and-functional-capacity-studies-copernicus
#4
JOURNAL ARTICLE
Agnieszka Kujawska, Guillermo F López Sánchez, Flaka Hoti, Sławomir Kujawski, Paweł Zalewski, Kornelia Kędziora-Kornatowska
BACKGROUND: To examine the relationship between the frequency of physical activities and food product consumption with body composition change after two years in a sample of older people. METHODS: Body composition, mass change, frequency of physical activity, and food products consumption were measured. Depression severity, health self-assessment, cognitive function, and demographic data were included as confounders. RESULTS: There were no significant changes in body composition except for a reduction in visceral fat level within two years ( p < 0...
April 11, 2023: Nutrients
https://read.qxmd.com/read/36978933/aging-accelerated-mouse-prone-8-samp8-mice-experiment-and-network-pharmacological-analysis-of-aged-liupao-tea-aqueous-extract-in-delaying-the-decline-changes-of-the-body
#5
JOURNAL ARTICLE
Wenjing Pan, Wangshu Li, Huan Wu, Xinya Xie, Mingwei Xie, Qing Nie, Zhonghua Liu, Shuxian Cai
Aging and metabolic disorders feedback and promote each other and are closely related to the occurrence and development of cardiovascular disease, type 2 diabetes, neurodegeneration and other degenerative diseases. Liupao tea is a geographical indication product of Chinese dark tea, with a "red, concentrated, aged and mellow" flavor quality. In this study, the aqueous extract of aged Liupao tea (ALPT) administered by continuous gavage significantly inhibited the increase of visceral fat and damage to the intestinal-liver-microbial axis in high-fat modeling of SAMP8 (P8+HFD) mice...
March 10, 2023: Antioxidants (Basel, Switzerland)
https://read.qxmd.com/read/36558368/a-60-day-green-tea-extract-supplementation-counteracts-the-dysfunction-of-adipose-tissue-in-overweight-post-menopausal-and-class-i-obese-women
#6
RANDOMIZED CONTROLLED TRIAL
Mariangela Rondanelli, Clara Gasparri, Simone Perna, Giovanna Petrangolini, Pietro Allegrini, Teresa Fazia, Luisa Bernardinelli, Alessandro Cavioni, Francesca Mansueto, Letizia Oberto, Zaira Patelli, Alice Tartara, Antonella Riva
Menopause is characterized by weight gain and increased visceral fat, which acts as an endocrine organ secreting proinflammatory adipocytokines, with consequent increased risk of metabolic disorders. The aim of this double-blind, placebo-controlled randomized trial was to evaluate the effects of a 60-day dietary supplementation using Camellia sinensis leaf extract on adipose tissue dysfunction in overweight or class I obese post-menopausal, sedentary women. Primary endpoints were the respiratory quotient (RQ), the percentage of carbohydrates (%CHO), the percentage of fat oxidation (%FAT), and the resting energy expenditure (REE) measured by indirect calorimetry...
December 7, 2022: Nutrients
https://read.qxmd.com/read/36505232/sichuan-dark-tea-improves-lipid-metabolism-and-prevents-aortic-lipid-deposition-in-diet-induced-atherosclerosis-model-rats
#7
JOURNAL ARTICLE
Rui Lu, Takumi Sugimoto, Tomoe Tsuboi, Tatsushi Sekikawa, Mamoru Tanaka, Xiaohua Lyu, Shinji Yokoyama
BACKGROUND AND AIMS: Sichuan dark tea (ST), Zangcha, is a traditional fermented Chinese tea found in Sichuan and Tibet and claimed for beneficial effects against lifestyle-related metabolic disorders. We examined the effects of ST on lipid metabolism and atherosclerosis. METHODS AND RESULTS: Sichuan dark tea was given to fat-rich diet-induced atherosclerosis model rats in comparison with dark-fermented Chinese Pu-erh tea (PT) and Japanese green tea (GT). After 8 weeks of feeding, ST and PT induced an increase in high-density lipoprotein (HDL)-cholesterol and a decrease in glucose, and ST decreased triglyceride in plasma...
2022: Frontiers in Nutrition
https://read.qxmd.com/read/36360069/preventive-effects-of-different-black-and-dark-teas-on-obesity-and-non-alcoholic-fatty-liver-disease-and-modulate-gut-microbiota-in-high-fat-diet-fed-mice
#8
JOURNAL ARTICLE
Bangyan Li, Qianqian Mao, Ruogu Xiong, Dandan Zhou, Siyu Huang, Adila Saimaiti, Ao Shang, Min Luo, Hangyu Li, Huabin Li, Sha Li
Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading public health challenge and is closely associated with metabolic syndromes, such as obesity. Intestinal microbiota dysbiosis could play a vital role in the pathogenesis and progression of NAFLD. Tea is the second most popular health drink in the world behind water, and exhibits many health-promoting effects. In this study, the protective effects of different black and dark teas on NAFLD induced by long-term high-fat diet (HFD) exposure and their regulation of gut microbiota were evaluated and explored...
October 31, 2022: Foods (Basel, Switzerland)
https://read.qxmd.com/read/34844584/athrixia-phylicoides-tea-infusion-bushman-tea-improves-adipokine-balance-glucose-homeostasis-and-lipid-parameters-in-a-diet-induced-metabolic-syndrome-rat-model
#9
JOURNAL ARTICLE
Madigoahle A M Mokwena, Godwill Azeh Engwa, Benedicta N Nkeh-Chungag, Constance R Sewani-Rusike
BACKGROUND: Central obesity and insulin resistance are associated with metabolic syndrome (MetS) which is aggravated by diet and sedentary lifestyle. Athrixia phylicoides (AP) is reported by rural communities to have medicinal benefits associated with MetS such as obesity and type 2 diabetes. This study was aimed to investigate the effects of AP on diet-induced MetS in Wistar rats to validate its ethnopharmacological use. METHODS: AP was profiled for phytochemicals by LC-MS...
November 29, 2021: BMC complementary medicine and therapies
https://read.qxmd.com/read/34643713/diet-induced-fasting-ghrelin-elevation-reflects-the-recovery-of-insulin-sensitivity-and-visceral-adiposity-regression
#10
RANDOMIZED CONTROLLED TRIAL
Gal Tsaban, Anat Yaskolka Meir, Hila Zelicha, Ehud Rinott, Alon Kaplan, Aryeh Shalev, Amos Katz, Dov Brikner, Matthias Blüher, Uta Ceglarek, Michael Stumvoll, Meir J Stampfer, Iris Shai
CONTEXT: Lower fasting ghrelin levels (FGL) are associated with obesity and metabolic syndrome. OBJECTIVE: We aimed to explore the dynamics of FGL during weight loss and its metabolic and adiposity-related manifestations beyond weight loss. METHODS: This was a secondary analysis of a clinical trial that randomized participants with abdominal obesity/dyslipidemia to 1 of 3 diets: healthy dietary guidelines (HDG), Mediterranean diet (MED), or green-MED diet, all combined with physical activity (PA)...
January 18, 2022: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/34624188/the-effects-of-saffron-petals-and-damask-rose-petals-on-biochemical-and-inflammatory-measurements
#11
JOURNAL ARTICLE
Nazanin Majidi, Mahboubeh Kosari Monfared, Fatemeh Mazaheri-Eftekhar, Ariyo Movahedi, Majid Karandish
OBJECTIVES: Diabetes is a chronic disease caused by high blood sugar greatly affected by diet. The chemical medicines applied to treat diabetes usually have side effects. This study aimed to investigate the effect of saffron petals, damask rose petals, and saffron-damask rose petal herbal teas on weight loss, fasting blood sugar, lipid profile, and the inflammatory factors of diabetic rats. METHODS: In this study, 40 male Sprague Dawley rats with an average age of four weeks received a high-calorie, high-fat, high-sugar diet for nine weeks...
June 1, 2022: Journal of Complementary & Integrative Medicine
https://read.qxmd.com/read/34561541/the-combined-effect-of-green-tea-and-%C3%AE-glucosyl-hesperidin-in-preventing-obesity-a-randomized-placebo-controlled-clinical-trial
#12
RANDOMIZED CONTROLLED TRIAL
Ren Yoshitomi, Mao Yamamoto, Motofumi Kumazoe, Yoshinori Fujimura, Madoka Yonekura, Yasuyo Shimamoto, Akari Nakasone, Satoshi Kondo, Hiroki Hattori, Akane Haseda, Jun Nishihira, Hirofumi Tachibana
Green tea, a widely consumed beverage in Asia, contains green tea catechins effective against obesity, especially epigallocatechin-3-O-gallate (EGCG), but must be consumed in an impractically huge amount daily to elicit its biological effect. Meanwhile, citrus polyphenols have various physiological effects that could enhance EGCG functionality. Here we investigated the antiobesity effect of a combination of EGCG and α-glucosyl hesperidin, a citrus polyphenol, at doses that have not been previously reported to exert antiobesity effects by themselves in any clinical trial...
September 24, 2021: Scientific Reports
https://read.qxmd.com/read/34204055/matcha-green-tea-alleviates-non-alcoholic-fatty-liver-disease-in-high-fat-diet-induced-obese-mice-by-regulating-lipid-metabolism-and-inflammatory-responses
#13
JOURNAL ARTICLE
Jihong Zhou, Yueer Yu, Lejia Ding, Ping Xu, Yuefei Wang
Lately, matcha green tea has gained popularity as a beverage and food additive. It has proved to be effective in preventing obesity and related metabolic syndromes. However, the underlying mechanisms of its control effects against non-alcoholic fatty liver disease (NAFLD) are complicated and remain elusive. In the present study, we performed an in vivo experiment using male C57BL/6 mice fed with a high-fat diet and simultaneously treated with matcha for six weeks. Serum biochemical parameters, histological changes, lipid accumulation, inflammatory cytokines, and relevant indicators were examined...
June 6, 2021: Nutrients
https://read.qxmd.com/read/34178857/hydro-alcoholic-green-tea-extract-effect-on-high-fat-diet-treated-nmri-mice-and-3t3l1-cells
#14
JOURNAL ARTICLE
Farnaz Banakar, Azadeh Ebrahim-Habibi, Mahsa Mohammad-Amoli, Raheleh Kheirbakhsh, Mahsa Sadeghi-Afjeh, Shadab Shahriari, Bagher Larijani
PURPOSE: In order to counteract the obesity has epidemics, since current anti-obesity drugs effects remain limited, there is a need to provide new options. As a project aiming to assess potential anti obesity natural compounds, the effects of consumption of a minimal dose of green tea hydro alcoholic extract (GT) on adipocyte differentiation of 3T3L1 cell line were investigated. METHODS: Obesity was induced in female NMRI mice (which are less used overall) by the use of a high fat diet...
June 2021: Journal of Diabetes and Metabolic Disorders
https://read.qxmd.com/read/33946279/preventive-effects-of-green-tea-extract-against-obesity-development-in-zebrafish
#15
JOURNAL ARTICLE
Liqing Zang, Yasuhito Shimada, Hiroko Nakayama, Hirotaka Katsuzaki, Youngil Kim, Djong-Chi Chu, Lekh Raj Juneja, Junya Kuroyanagi, Norihiro Nishimura
Various natural products (NPs) have been used to treat obesity and related diseases. However, the best way to fight obesity is preventive, with accurate body weight management through exercise, diet, or bioactive NPs to avoid obesity development. We demonstrated that green tea extract (GTE) is an anti-obesity NP using a zebrafish obesity model. Based on a hypothesis that GTE can prevent obesity, the objective of this study was to assess GTE's ability to attenuate obesity development. Juvenile zebrafish were pretreated with GTE for seven days before obesity induction via a high-fat diet; adult zebrafish were pretreated with GTE for two weeks before obesity induction by overfeeding...
April 30, 2021: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/33322023/anti-obesity-natural-products-tested-in-juvenile-zebrafish-obesogenic-tests-and-mouse-3t3-l1-adipogenesis-assays
#16
JOURNAL ARTICLE
Hiroko Nakayama, Kanae Hata, Izumi Matsuoka, Liqing Zang, Youngil Kim, Djongchi Chu, Lekh Raj Juneja, Norihiro Nishimura, Yasuhito Shimada
(1) Background: The obesity epidemic has been drastically progressing in both children and adults worldwide. Pharmacotherapy is considered necessary for its treatment. However, many anti-obesity drugs have been withdrawn from the market due to their adverse effects. Instead, natural products (NPs) have been studied as a source for drug discovery for obesity, with the goal of limiting the adverse effects. Zebrafish are ideal model animals for in vivo testing of anti-obesity NPs, and disease models of several types of obesity have been developed...
December 10, 2020: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/33050029/epigallocatechin-3-gallate-reduces-visceral-adiposity-partly-through-the-regulation-of-beclin1-dependent-autophagy-in-white-adipose-tissues
#17
JOURNAL ARTICLE
Cheoljun Choi, Hyun-Doo Song, Yeonho Son, Yoon Keun Cho, Sang-Yeop Ahn, Young-Suk Jung, Young Cheol Yoon, Sung Won Kwon, Yun-Hee Lee
Epigallocatechin-3-gallate (EGCG) is a primary bioactive phytochemical in green tea. Its therapeutic potential in metabolic diseases has been reported; however, the molecular mechanisms of the anti-obesity effect of EGCG have not been fully elucidated. In this study, we examined the effects of EGCG on lipid metabolism and autophagy in adipose tissue. After 8 weeks of high-fat diet feeding, mice were treated with EGCG (20 mg/kg/day) for 2 weeks to test in vivo anti-obesity effects of EGCG. EGCG treatment improved glucose tolerance and caused body weight loss...
October 8, 2020: Nutrients
https://read.qxmd.com/read/32697259/fubrick-tea-attenuates-high-fat-diet-induced-fat-deposition-and-metabolic-disorder-by-regulating-gut-microbiota-and-caffeine-metabolism
#18
JOURNAL ARTICLE
Nana Jing, Xiaoxia Liu, Mingliang Jin, Xingbin Yang, Xin Hu, Caiyan Li, Ke Zhao
Fubrick tea aqueous extract (FTEs) has been reported to improve lipid metabolism and gut microbiota communities in mice and humans. However, it is still unclear how FTEs prevents obesity through gut microbiota, and whether some other regulatory mechanisms are involved in the process. Here, we found that FTEs supplementation effectively alleviated the body weight gain, visceral fat accumulation, dyslipidemia, and impaired glucose tolerance induced by a high-fat diet (HFD), and fecal microbiota transplantation (FMT) from FTEs-treated mice showed similar protective effects as FTEs supplementation in mice fed with a HFD...
July 22, 2020: Food & Function
https://read.qxmd.com/read/32458968/green-tea-polyphenols-ameliorate-metabolic-abnormalities-and-insulin-resistance-by-enhancing-insulin-signalling-in-skeletal-muscle-of-zucker-fatty-rats
#19
JOURNAL ARTICLE
Jing Cheng, Yi Tan, Jiong Zhou, Linda Xiao, Michael Johnson, Xianqin Qu
In the present study, we evaluated the metabolic effects of green tea polyphenols (GTPs) in high-fat diet (HFD) fed Zucker fatty (ZF) rats, in particular the effects of GTP on skeletal muscle insulin sensitivity. Body weight, visceral fat, glucose tolerance, lipid profiles and whole-body insulin sensitivity were measured in HFD-fed ZF rats after 8-week-treatment with GTP (200 mg/kg of body weight) or saline (5 ml/kg of body weight). Zucker lean rats were studied as controls. Ex vivo insulin-mediated muscle glucose uptake was assessed...
May 29, 2020: Clinical Science (1979-)
https://read.qxmd.com/read/32095935/effects-of-green-tea-extract-supplementation-and-endurance-training-on-irisin-pro-inflammatory-cytokines-and-adiponectin-concentrations-in-overweight-middle-aged-men
#20
RANDOMIZED CONTROLLED TRIAL
Reza Bagheri, Amir Rashidlamir, Damoon Ashtary-Larky, Alexei Wong, Brandon Grubbs, Mohamad S Motevalli, Julien S Baker, Ismail Laher, Hassane Zouhal
PURPOSE: Green tea extract (GTE) supplementation has been proposed to possess anti-inflammatory properties. This study assessed the effects of GTE on endurance training (ET) induced changes on irisin, pro-inflammatory cytokines, adiponectin and anthropometric indices in overweight middle-aged males. METHODS: Participants were randomly assigned to three groups (n = 15): endurance training + placebo (ET + P), endurance training + green tea extract supplementation (ET + GTE), and no endurance training + placebo (P)...
April 2020: European Journal of Applied Physiology
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