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https://www.readbyqxmd.com/read/29345718/evaluation-of-the-morphological-characteristic-and-sex-differences-of-sternum-by-multi-detector-computed-tomography
#1
Sibel Ateşoğlu, Mustafa Deniz, Ayşe İmge Uslu
BACKGROUND: Sternum is one of the skeleton parts which have frequently congenital anomalies and variations are commonly used by researchers in determining sex. We evaluated the morphological characteristics and sex-related changes of the sternum in adult individuals using multidetector CT in our study. MATERIALS AND METHODS: 200 adults (103 female and 97 male) aged between 18-87 years were evaluated. Utilizing the morphological characteristics of the sternum based on the multi-slice images; length, width and the thickness of Manubrium, length, width and the thickness of Corpus Sterni, total length of Sternum, Sternal angle, Sternal index, length of the xiphoid process, the thickness of xiphoid process, the number of indents of xiphoid process were measured and a total of 20 parameters were evaluated by adding age, height and weight to these variables...
January 18, 2018: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/29239189/-immunotherapy-in-the-treatment-of-lung-cancer
#2
O Fiala, O Šorejs, M Pešek, J Fínek
BACKGROUND: Lung cancer occupies the leading position of cancer incidence and mortality worldwide, including in the Czech Republic. Despite significant advances in systemic oncology treatments, lung cancer still has the worst prognosis, which is driving the need for innovative therapies and methods to treat this disease. Immunotherapy is a developing area of systemic oncology treatment, which has recently begun to be significantly applied to patients with lung carcinoma. The most useful type of immunotherapy currently employs checkpoint inhibitors, including CTLA-4 inhibitors (ipilimumab and tremelimumab) and PD-1/PD-L1 inhibitors (nivolumab, pembrolizumab, durvalumab, and avelumab)...
2017: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/29221624/international-medical-graduates-in-nephrology-roles-rules-and-future-risks
#3
Jeffrey S Berns, Muriel Ghosn, Rodolfo R Altamirano
International medical graduates (IMGs) have become an increasingly essential part of many residency and fellowship programs in the United States. IMGs, who may be of either US or non-US citizenship, contribute significantly to the physician workforce across this country, particularly in underserved areas, as well as in their home countries on their return after training. Approximately 65% of nephrology fellows are IMGs, with most of these being non-US citizens. Non-US IMG applications for nephrology fellowship have been declining, exacerbating an ongoing shortage of nephrology trainees...
December 5, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29190402/resident-and-residency-characteristics-associated-with-self-reported-preparedness-for-population-health-management
#4
Erica K Schuster, Lars E Peterson
BACKGROUND AND OBJECTIVES: Population health management (PHM) is an important function of primary care with potential to improve outcomes and decrease costs, but is also among the most difficult strategies to implement in both practices and residency training. Our objective was to determine resident and residency program characteristics associated with graduates' reported preparation to perform PHM. METHODS: We used data from the American Board of Family Medicine (ABFM) Certification Examination registration questionnaire in 2014 and 2015 and ABFM administrative data...
November 2017: Family Medicine
https://www.readbyqxmd.com/read/29187780/the-skull-of-epidolops-ameghinoi-from-the-early-eocene-itabora%C3%A3-fauna-southeastern-brazil-and-the-affinities-of-the-extinct-marsupialiform-order-polydolopimorphia
#5
Robin M D Beck
The skull of the polydolopimorphian marsupialiform Epidolops ameghinoi is described in detail for the first time, based on a single well-preserved cranium and associated left and right dentaries plus additional craniodental fragments, all from the early Eocene (53-50 million year old) Itaboraí fauna in southeastern Brazil. Notable craniodental features of E. ameghinoi include absence of a masseteric process, very small maxillopalatine fenestrae, a prominent pterygoid fossa enclosed laterally by a prominent ectopterygoid crest, an absent or tiny transverse canal foramen, a simple, planar glenoid fossa, and a postglenoid foramen that is immediately posterior to the postglenoid process...
2017: Journal of Mammalian Evolution
https://www.readbyqxmd.com/read/29180562/the-single-graduate-medical-education-gme-accreditation-system-will-change-the-future-of-the-family-medicine-workforce
#6
Michael R Peabody, Thomas R O'Neill, Aimee R Eden, James C Puffer
BACKGROUND: Due to the Accreditation Council for Graduate Medical Education (ACGME)/American Osteopathic Association (AOA) single-accreditation model, the specialty of family medicine may see as many as 150 programs and 500 trainees in AOA-accredited programs seek ACGME accreditation. This analysis serves to better understand the composition of physicians completing family medicine residency training and their subsequent certification by the American Board of Family Medicine. METHODS: We identified residents who completed an ACGME-accredited or dual-accredited family medicine residency program between 2006 and 2016 and cross-tabulated the data by graduation year and by educational background (US Medical Graduate-MD [USMG-MD], USMG-DO, or International Medical Graduate-MD [IMG-MD]) to examine the cohort composition trend over time...
November 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29163118/semi-automated-anatomical-labeling-and-inter-subject-warping-of-high-density-intracranial-recording-electrodes-in-electrocorticography
#7
Liberty S Hamilton, David L Chang, Morgan B Lee, Edward F Chang
In this article, we introduce img_pipe, our open source python package for preprocessing of imaging data for use in intracranial electrocorticography (ECoG) and intracranial stereo-EEG analyses. The process of electrode localization, labeling, and warping for use in ECoG currently varies widely across laboratories, and it is usually performed with custom, lab-specific code. This python package aims to provide a standardized interface for these procedures, as well as code to plot and display results on 3D cortical surface meshes...
2017: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/29129176/composite-reliability-of-workplace-based-assessment-of-international-medical-graduates
#8
Balakrishnan Kichu R Nair, Joyce Mw Moonen-van Loon, Mulavana Parvathy, Brian C Jolly, Cees Pm van der Vleuten
OBJECTIVE: The fitness to practise of international medical graduates (IMGs) is usually evaluated with standardised assessment tests. The performance rather than the competency of practising doctors should, however, be assessed, for which reason workplace-based assessment (WBA) has gained increasing attention. Our aim was to assess the composite reliability of WBA instruments for assessing IMGs. DESIGN AND SETTING: Between June 2010 and April 2015, 142 IMGs were assessed by 99 calibrated assessors; each was assessed in the workplace over 6 months...
November 20, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/29128927/toll-like-receptors-participate-in-naegleria-fowleri-recognition
#9
Moisés Martínez-Castillo, Leopoldo Santos-Argumedo, José Manuel Galván-Moroyoqui, Jesús Serrano-Luna, Mineko Shibayama
Naegleria fowleri is a protozoan that invades the central nervous system and causes primary amoebic meningoencephalitis. It has been reported that N. fowleri induces an important inflammatory response during the infection. In the present study, we evaluated the roles of Toll-like receptors in the recognition of N. fowleri trophozoites by human mucoepithelial cells, analyzing the expression and production of innate immune response mediators. After amoebic interactions with NCI-H292 cells, the expression and production levels of IL-8, TNF-α, IL-1β, and human beta defensin-2 were evaluated by RT-PCR, ELISA, immunofluorescence, and dot blot assays, respectively...
November 11, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29127889/nitric-oxide-and-arginase-levels-in-peri-implant-tissues-after-delayed-loading
#10
Ceren Gokmenoglu, Nurdan Ozmeric, Caglar Sungur, Raziye Sahin Bildik, Imge Erguder, Serenay Elgun
OBJECTIVE: Nitric oxide (NO) is synthesized from the conversion of L-arginine to L-citrulline by NO synthase (NOS). Arginase can compete with NOS for the common substrate L-arginine, and thus inhibit NO production. NO levels and arginase ezyme might affect the bone remodeling cycle around implants. The aim of this studywas to investigate NO and arginase levels in gingival crevicular fluid (GCF), peri-implant sulcular fluid (PISF), and saliva. MATERIALS AND METHODS: Twenty patients with one or more implants (Straumann(®); Institute Straumann AG, Basel, Switzerland) restored with fixed crown prostheses were included in the study...
October 23, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29056347/addressing-professionalism-social-and-communication-competencies-in-surgical-residency-via-integrated-humanities-workshops-a-pilot-curriculum
#11
Jennifer Colvin, Judith French, Allan Siperstein, Tony R Capizzani, Vikram D Krishnamurthy
OBJECTIVE: We aimed to conduct professionalism and social competencies (PSC) training by integrating humanities into structured workshops, and to assess reception of this curriculum by first-year surgical residents. DESIGN: An IRB-approved, pilot curriculum consisting of 4 interactive workshops for surgical interns was developed. The workshops were scheduled quarterly, often in small group format, and supplemental readings were assigned. Humanities media utilized to illustrate PSC included survival scenarios, reflective writing, television portrayals, and social media...
October 19, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/29045984/results-of-the-2017-national-resident-matching-program%C3%A2-and-the-american-osteopathic-association-intern-resident-registration-program
#12
Stanley M Kozakowski, Alexandra Travis, Julie P Marcinek, Ashley Bentley, Gerald T Fetter
The purpose of medicine as a profession is to meet the health needs of people and communities. Despite empirical evidence worldwide that an appropriate foundation of primary care in a health care system leads to improved health outcomes, improved experience of health care, a reduction in health disparities, and lower overall cost of care, publicly available data from National Resident Matching Program® (NRMP) and the American Osteopathic Association (AOA) Intern/Resident Registration Program show that PGY-1 family medicine and primary care positions offered in the NRMP Match continue to grow, but are losing ground in comparison to the growth of non-primary care specialties...
October 2017: Family Medicine
https://www.readbyqxmd.com/read/29033909/benzene-and-naphthalene-degrading-bacterial-communities-in-an-oil-sands-tailings-pond
#13
Fauziah F Rochman, Andriy Sheremet, Ivica Tamas, Alireza Saidi-Mehrabad, Joong-Jae Kim, Xiaoli Dong, Christoph W Sensen, Lisa M Gieg, Peter F Dunfield
Oil sands process-affected water (OSPW), produced by surface-mining of oil sands in Canada, is alkaline and contains high concentrations of salts, metals, naphthenic acids, and polycyclic aromatic compounds (PAHs). Residual hydrocarbon biodegradation occurs naturally, but little is known about the hydrocarbon-degrading microbial communities present in OSPW. In this study, aerobic oxidation of benzene and naphthalene in the surface layer of an oil sands tailings pond were measured. The potential oxidation rates were 4...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29025820/well-being-of-family-medicine-graduates
#14
Olga Szafran, Wayne Woloschuk, Jacqueline M I Torti, Douglas Myhre
OBJECTIVE: To determine family medicine graduates' professional and personal well-being, general health status, stress levels, coping strategies, and the degree to which they felt supported or isolated in professional life; and to compare findings by sex, practice location, and location of medical school (Canadian medical graduates [CMGs] vs international medical graduates [IMGs]). DESIGN: Retrospective, cross-sectional survey. SETTING: University of Alberta in Edmonton and the University of Calgary in Alberta...
October 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29025807/examination-outcomes-and-work-locations-of-international-medical-graduate-family-medicine-residents-in-canada
#15
Maria Mathews, Rima Kandar, Steve Slade, Yanqing Yi, Sue Beardall, Ivy Bourgeault
OBJECTIVE: To describe the postgraduate medical education (PGME) examination outcomes and work locations of international medical graduates (IMGs); and to identify differences between Canadians studying abroad (CSAs) and non-CSAs. DESIGN: Cohort study using data from the National IMG Database and Scott's Medical Database. SETTING: Canada. PARTICIPANTS: All IMGs who had first entered a family medicine residency program between 2005 and 2009, with the exclusion of US graduates, visa trainees, and fellowship trainees...
October 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28983854/a-pilot-study-examining-factors-influencing-readiness-to-progress-to-indirect-supervision-among-first-year-residents-in-a-general-psychiatry-training-program
#16
Bryan Touchet, Ashley Walker, Sarah Flanders, Heather McIntosh
OBJECTIVE: In the first year of training, psychiatry residents progress from direct supervision to indirect supervision but factors predicting time to transition between these levels of supervision are unknown. This study aimed to examine times for transition to indirect levels of supervision and to identify resident factors associated with slower progression. METHODS: The authors compiled data from training files from years 2011-2015, including licensing exam scores, age, gender, medical school, month of first inpatient psychiatry rotation, and transition times between levels of supervision...
October 5, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/28979916/addressing-the-physicians-shortage-in-developing-countries-by-accelerating-and-reforming-the-medical-education-is-it-possible
#17
Mustafa Al-Shamsi
INTRODUCTION: Doctors' shortage has remained a concern worldwide. The developed countries started aids to recruit international medical graduates (IMG) to cope with the defects that the health care system suffers from; however, this solution may not work in developing countries that have a limited resource and poor budget to spend on the health care system. This study aims to present an alternative way to approach the physicians' shortage by accelerating undergraduate medical education and reform some post-graduate courses in order to cope with this problem...
October 2017: Journal of Advances in Medical Education & Professionalism
https://www.readbyqxmd.com/read/28973033/integrative-genetic-analysis-suggests-that-skin-color-modifies-the-genetic-architecture-of-melanoma
#18
Imge Hulur, Andrew D Skol, Eric R Gamazon, Nancy J Cox, Kenan Onel
Melanoma is the deadliest form of skin cancer and presents a significant health care burden in many countries. In addition to ultraviolet radiation in sunlight, the main causal factor for melanoma, genetic factors also play an important role in melanoma susceptibility. Although genome-wide association studies have identified many single nucleotide polymorphisms associated with melanoma, little is known about the proportion of disease risk attributable to these loci and their distribution throughout the genome...
2017: PloS One
https://www.readbyqxmd.com/read/28956675/ingenol-mebutate-for-the-treatment-of-actinic-keratosis-effectiveness-and-safety-in-246-patients-treated-in-real-life-clinical-practice
#19
Rosa Ortega Del Olmo, Rafael Salido-Vallejo
INTRODUCTION: The aim of the study was to evaluate the results on effectiveness and safety of topical treatment for actinic keratosis (AK) with ingenol mebutate gel (IMG) in real-life conditions and to perform an analysis of the factors that may influence the treatment outcomes. MATERIALS AND METHODS: Retrospective study of patients with non-hyperkeratotic AK lesions prescribed with IMG in Spain according to clinical practice. Dermatologists reported the characteristics of patients and AK at baseline, and the findings observed up to 60 d after treatment...
November 8, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28948352/nitrogen-form-and-mycorrhizal-inoculation-amount-and-timing-affect-flavonol-biosynthesis-in-onion-allium-cepa-l
#20
Mohanna Mollavali, Henrike Perner, Sascha Rohn, Peer Riehle, Franziska S Hanschen, Dietmar Schwarz
Mycorrhizal symbiosis is known to be the most prevalent form of fungal symbiosis with plants. Although some studies focus on the importance of mycorrhizal symbiosis for enhanced flavonoids in the host plants, a comprehensive understanding of the relationship still is lacking. Therefore, we studied the effects of mycorrhizal inoculation of onions (Allium cepa L.) regarding flavonol concentration and the genes involved in flavonol biosynthesis when different forms of nitrogen were supplied. We hypothesized that mycorrhizal inoculation can act as a biotic stress and might lead to an increase in flavonols and expression of related genes...
September 26, 2017: Mycorrhiza
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