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https://www.readbyqxmd.com/read/28416839/-a-correlation-analysis-of-the-ankle-ct-and-ankle-fracture-classification
#1
X F Gong, Y W Lyu, J H Wang, Y Wang, Y Wu, M Y Wang
OBJECTIVE: To summarize the CT features of ankle fracture and to analyze the relationship between the CT images and the most commonly used ankle fracture classification. METHODS: With 369 cases of adult ankle fractures analyzed retrospectively, the CT images 1 cm above the ankle joint and its characteristics, the Danis-Weber classification of ankle fracture were studied, and so was the relationship between CT images and the fracture classification. RESULTS: There were 8 forms of CT images...
April 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28365064/subject-specific-2d-3d-image-registration-and-kinematics-driven-musculoskeletal-model-of-the-spine
#2
A H Eskandari, N Arjmand, A Shirazi-Adl, F Farahmand
An essential input to the musculoskeletal (MS) trunk models that estimate muscle and spine forces is kinematics of the thorax, pelvis, and lumbar vertebrae. While thorax and pelvis kinematics are usually measured via skin motion capture devices (with inherent errors on the proper identification of the underlying bony landmarks and the relative skin-sensor-bone movements), those of the intervening lumbar vertebrae are commonly approximated at fixed proportions based on the thorax-pelvis kinematics. This study proposes an image-based kinematics measurement approach to drive subject-specific (musculature, geometry, mass, and center of masses) MS models...
March 21, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28344716/an-examination-of-entrance-criteria-for-international-medical-graduates-imgs-into-canadian-psychiatry-residency-programs
#3
Ashok Soma, Mathew Myatt, Mario McKenna, Soma Ganesa, Ka Wai Leung
BACKGROUND: Although international medical graduates (IMGs) are essential in health care service delivery, a gap exists in the literature about how IMGs are selected into psychiatry residency programs in Canada. The purpose of this study was to identify the relative weight or importance that Canadian program directors (PDs) of psychiatry place on certain selection criteria when matching IMGs into residency programs. METHODS: We electronically distributed a web-based questionnaire to 16 university residency program directors of psychiatry in Canada...
February 2017: Canadian Medical Education Journal
https://www.readbyqxmd.com/read/28344705/the-influence-of-globalization-on-medical-regulation-a-descriptive-analysis-of-international-medical-graduates-registered-through-alternative-licensure-routes-in-ontario
#4
Wendy Yen, Kathryn Hodwitz, Niels Thakkar, Maria Athina Tina Martimianakis, Dan Faulkner
The increasing globalization of the medical profession has influenced health policy, health human resource planning, and medical regulation in Canada. Since the early 2000s, numerous policy initiatives have been created to facilitate the entry of international medical graduates (IMGs) into the Canadian workforce. In Ontario, the College of Physicians and Surgeons of Ontario (CPSO) developed alternative licensure routes to increase the ability of qualified IMGs to obtain licenses to practice. The current study provides demographic and descriptive information about the IMGs registered through the CPSO's alternative licensure routes between 2000 and 2012...
December 2016: Canadian Medical Education Journal
https://www.readbyqxmd.com/read/28301489/comparative-analysis-of-fecal-microbial-communities-in-cattle-and-bactrian-camels
#5
Liang Ming, Li Yi, Siriguleng, Surong Hasi, Jing He, Le Hai, Zhaoxia Wang, Fucheng Guo, Xiangyu Qiao, Jirimutu
Bactrian camels may have a unique gastrointestinal (GI) microbiome because of their distinctive digestive systems, unique eating habits and extreme living conditions. However, understanding of the microbial communities in the Bactrian camel GI tract is still limited. In this study, microbial communities were investigated by comparative analyses of 16S rRNA hypervariable region V4 sequences of fecal bacteria sampled from 94 animals in four population groups: Inner Mongolian cattle (IMG-Cattle), Inner Mongolian domestic Bactrian camels (IMG-DBC), Mongolian domestic Bactrian camels (MG-DBC), and Mongolian wild Bactrian camels (MG-WBC)...
2017: PloS One
https://www.readbyqxmd.com/read/28276554/1-8-bis-silylamido-naphthalene-complexes-of-magnesium-and-zinc-synthesised-through-alkane-elimination-reactions
#6
Mark A Bradley, Chris Birchall, Alexander J Blake, William Lewis, Graeme J Moxey, Deborah L Kays
The reactions between magnesium or zinc alkyls and 1,8-bis(triorganosilyl)diaminonaphthalenes afford the 1,8-bis(triorganosilyl)diamidonaphthalene complexes with elimination of alkanes. The reaction between 1,8-C10H6(NSiMePh2H)2 and one or two equivalents of Mg(n)Bu2 affords two complexes with differing coordination environments for the magnesium; the reaction between 1,8-C10H6(NSiMePh2H)2 and Mg(n)Bu2 in a 1 : 1 ratio affords 1,8-C10H6(NSiMePh2)2{Mg(THF)2} (1), which features a single magnesium centre bridging both ligand nitrogen donors, whilst treatment of 1,8-C10H6(NSiR3H)2 (R3 = MePh2, (i)Pr3) with two equivalents of Mg(n)Bu2 affords the bimetallic complexes 1,8-C10H6(NSiR3)2{(n)BuMg(THF)}2 (R3 = MePh22, R3 = (i)Pr33), which feature four-membered Mg2N2 rings...
March 9, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28211005/resequencing-and-annotation-of-the-nostoc-punctiforme-attc-29133-genome-facilitating-biofuel-and-high-value-chemical-production
#7
Luis E Moraes, Matthew J Blow, Erik R Hawley, Hailan Piao, Rita Kuo, Jennifer Chiniquy, Nicole Shapiro, Tanja Woyke, James G Fadel, Matthias Hess
Cyanobacteria have the potential to produce bulk and fine chemicals and members belonging to Nostoc sp. have received particular attention due to their relatively fast growth rate and the relative ease with which they can be harvested. Nostoc punctiforme is an aerobic, motile, Gram-negative, filamentous cyanobacterium that has been studied intensively to enhance our understanding of microbial carbon and nitrogen fixation. The genome of the type strain N. punctiforme ATCC 29133 was sequenced in 2001 and the scientific community has used these genome data extensively since then...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28150571/sanguibacter-gelidistatuariae-sp-nov-a-novel-psychrotolerant-anaerobe-from-an-ice-sculpture-in-antarctica-and-emendation-of-descriptions-for-the-family-sanguibacteraceae-the-genus-sanguibacter-and-species-s-antarcticus-s-inulinus-s-kedieii-s-marinus-s-soli
#8
Elena V Pikuta, Zhe Lyu, Melissa D Williams, Nisha B Patel, Yuchen Liu, Richard Brice Hoover, Hans-Jürgen Busse, Paul A Lawson, William B Whitman
A novel psychrotolerant bacterium strain ISLP-3T was isolated from a sample of naturally formed ice sculpture on the shore of Lake Podprudnoye in Antarctica. Cells were motile, stained Gram positive, non-spore-forming, straight or slightly curved rods with the shape of a baseball bat. The new isolate was facultatively anaerobic and catalase positive. Growth occurred at 3-35 ºC with an optimum at 24 °C, 0-2 % w/v NaCl with an optimum at 0.3 % and pH 6.2 - 9.5 with an optimum 7.5. Strain ISLP-3T grew on several carbon sources, with the best growth on D-cellobiose...
February 1, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28066603/characteristics-of-cardiothoracic-surgeons-practicing-at-the-top-ranked-us-institutions
#9
Carlo Maria Rosati, Leonidas G Koniaris, Daniela Molena, David Blitzer, Katherine W Su, Mohammad Tahboub, Panos N Vardas, Leonard N Girardi, Mario Gaudino
BACKGROUND: We aimed to determine which factors distinguish cardiothoracic (CT) surgeons practicing at the top-ranked US institutions from their peers. METHODS: Using online resources, we collected demographics, training information and academic metrics of 694 cardiac (n=489; 70%) and thoracic (n=205; 30%) surgeons practicing at 57 preeminent US institutions, including those with the highest US News & World Report ranking ("top CT centers"). RESULTS: Two hundred and ninety-nine (43...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28048165/su-f-j-60-impact-of-dir-method-on-treatment-dose-wrapping
#10
A Qin, J Liang, J Zhu, X Ding, E Castillo, T Guerrero, D Yan
PURPOSE: To investigate clinical relevant discrepancy between doses wrapped by pure image and biomechanical model based deformable registration (DIR). METHODS: 12 patients, each with a CT pair, were included (5 H&N, 5 Prostate and 2 Lung). A research DIR tool (ADMRIE) was utilized for image based DIR (IMG-DIR). To assure organ matching, contour constrain was applied for prostate patients. Tetrahedron meshes were generated for organs (parotid, bladder, rectum and lung)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28033485/acculturation-needs-of-pediatric-international-medical-graduates-a-qualitative-study
#11
Amanda D Osta, Michelle M Barnes, Regina Pessagno, Alan Schwartz, Laura E Hirshfield
Phenomenon: International medical graduates (IMGs) play a key role in host countries' health systems but face unique challenges, which makes effective, tailored support for IMGs essential. Prior literature describing the acculturation needs of IMGs focused primarily on communication content and style. We conducted a qualitative study to explore acculturation that might be specific to IMG residents who care for children. APPROACH: In a study conducted from November 2011 to April 2012, we performed four 90-minute semistructured focus groups with 26 pediatric IMG residents from 12 countries...
December 29, 2016: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28031610/the-need-for-a-comprehensive-medication-safety-module-in-medical-education
#12
Sujith John Chandy
OBJECTIVE: A rising number of medicines and minimal emphasis on rational prescribing in the medical curriculum may compromise medication safety. There is no focused module in the curriculum dealing with factors affecting safety such as quality, medicines management, rational use, and approach to adverse effects. Creating awareness of these issues would hopefully plant a seed of safe prescribing and encourage pharmacovigilance. A study was therefore done to determine the need for such a module...
October 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/27997264/decrease-in-ionized-and-total-magnesium-blood-concentrations-in-endurance-athletes-following-an-exercise-bout-restores-within-hours-potential-consequences-for-monitoring-and-supplementation
#13
Rieneke Terink, Michael G J Balvers, Maria T Hopman, Renger F Witkamp, Marco Mensink, Jacqueline M T Klein Gunnewiek
Magnesium is essential for optimal sport performance, generating an interest to monitor its status in athletes. However, before measuring magnesium status in blood could become routine, more insight into its diurnal fluctuations and effects of exercise itself is necessary. Therefore, we measured the effect of an acute bout of exercise on ionized (iMg) and total plasma magnesium (tMg) in blood obtained from 18 healthy well-trained endurance athletes (age, 31.1 ± 8.1 yr.; VO2max, 50.9 ± 7.5 ml/kg/min) at multiple time points, and compared this with a resting situation...
December 20, 2016: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/27903896/img-abc-new-features-for-bacterial-secondary-metabolism-analysis-and-targeted-biosynthetic-gene-cluster-discovery-in-thousands-of-microbial-genomes
#14
Michalis Hadjithomas, I-Min A Chen, Ken Chu, Jinghua Huang, Anna Ratner, Krishna Palaniappan, Evan Andersen, Victor Markowitz, Nikos C Kyrpides, Natalia N Ivanova
Secondary metabolites produced by microbes have diverse biological functions, which makes them a great potential source of biotechnologically relevant compounds with antimicrobial, anti-cancer and other activities. The proteins needed to synthesize these natural products are often encoded by clusters of co-located genes called biosynthetic gene clusters (BCs). In order to advance the exploration of microbial secondary metabolism, we developed the largest publically available database of experimentally verified and predicted BCs, the Integrated Microbial Genomes Atlas of Biosynthetic gene Clusters (IMG-ABC) (https://img...
January 4, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/27903252/shifting-tides-in-the-emigration-patterns-of-canadian-physicians-to-the-united-states-a-cross-sectional-secondary-data-analysis
#15
Thomas R Freeman, Stephen Petterson, Sean Finnegan, Andrew Bazemore
BACKGROUND: The relative ease of movement of physicians across the Canada/US border has led to what is sometimes referred to as a 'brain drain' and previous analysis estimated that the equivalent of two graduating classes from Canadian medical schools were leaving to practice in the US each year. Both countries fill gaps in physician supply with international medical graduates (IMGs) so the movement of Canadian trained physicians to the US has international ramifications. Medical school enrolments have been increased on both sides of the border, yet there continues to be concerns about adequacy of physician human resources...
December 1, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27888178/perceived-causes-of-differential-attainment-in-uk-postgraduate-medical-training-a-national-qualitative-study
#16
Katherine Woolf, Antonia Rich, Rowena Viney, Sarah Needleman, Ann Griffin
OBJECTIVES: Explore trainee doctors' experiences of postgraduate training and perceptions of fairness in relation to ethnicity and country of primary medical qualification. DESIGN: Qualitative semistructured focus group and interview study. SETTING: Postgraduate training in England (London, Yorkshire and Humber, Kent Surrey and Sussex) and Wales. PARTICIPANTS: 137 participants (96 trainees, 41 trainers) were purposively sampled from a framework comprising: doctors from all stages of training in general practice, medicine, obstetrics and gynaecology, psychiatry, radiology, surgery or foundation, in 4 geographical areas, from white and black and minority ethnic (BME) backgrounds, who qualified in the UK and abroad...
November 25, 2016: BMJ Open
https://www.readbyqxmd.com/read/27876102/structural-functional-brain-changes-in-depressed-patients-during-and-after-electroconvulsive-therapy
#17
Antoine Yrondi, Patrice Péran, Anne Sauvaget, Laurent Schmitt, Christophe Arbus
OBJECTIVES: Electroconvulsive therapy (ECT) is a non-pharmacological treatment that is effective in treating severe and treatment-resistant depression. Although the efficacy of ECT has been demonstrated to treat major depressive disorder (MDD), the brain mechanisms underlying this process remain unclear. Structural-functional changes occur with the use of ECT as a treatment for depression based on magnetic resonance imaging (MRI). For this reason, we have tried to identify the changes that were identified by MRI to try to clarify some operating mechanisms of ECT...
November 23, 2016: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/27852927/evolution-of-trnaphe-img2-methyltransferases-involved-in-the-biosynthesis-of-wyosine-derivatives-in-archaea
#18
Jaunius Urbonavičius, Rasa Rutkienė, Anželika Lopato, Daiva Tauraitė, Jonita Stankevičiūtė, Agota Aučynaitė, Laura Kaliniene, Herman van Tilbeurgh, Rolandas Meškys
Tricyclic wyosine derivatives are found at position 37 of eukaryotic and archaeal tRNA(Phe) In Archaea, the intermediate imG-14 is targeted by three different enzymes that catalyze the formation of yW-86, imG, and imG2. We have suggested previously that a peculiar methyltransferase (aTrm5a/Taw22) likely catalyzes two distinct reactions: N(1)-methylation of guanosine to yield m(1)G; and C(7)-methylation of imG-14 to yield imG2. Here we show that the recombinant aTrm5a/Taw22-like enzymes from both Pyrococcus abyssi and Nanoarchaeum equitans indeed possess such dual specificity...
December 2016: RNA
https://www.readbyqxmd.com/read/27821527/left-right-analysis-of-mammary-gland-development-in-retinoid-x-receptor-%C3%AE-mice
#19
Jacqulyne P Robichaux, John W Fuseler, Shrusti S Patel, Steven W Kubalak, Adam Hartstone-Rose, Ann F Ramsdell
Left-right (L-R) differences in mammographic parenchymal patterns are an early predictor of breast cancer risk; however, the basis for this asymmetry is unknown. Here, we use retinoid X receptor alpha heterozygous null (RXRα(+/-)) mice to propose a developmental origin: perturbation of coordinated anterior-posterior (A-P) and L-R axial body patterning. We hypothesized that by analogy to somitogenesis-in which retinoic acid (RA) attenuation causes anterior somite pairs to develop L-R asynchronously-that RA pathway perturbation would likewise result in asymmetric mammary development...
December 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/27799466/img-vr-a-database-of-cultured-and-uncultured-dna-viruses-and-retroviruses
#20
David Paez-Espino, I-Min A Chen, Krishna Palaniappan, Anna Ratner, Ken Chu, Ernest Szeto, Manoj Pillay, Jinghua Huang, Victor M Markowitz, Torben Nielsen, Marcel Huntemann, T B K Reddy, Georgios A Pavlopoulos, Matthew B Sullivan, Barbara J Campbell, Feng Chen, Katherine McMahon, Steve J Hallam, Vincent Denef, Ricardo Cavicchioli, Sean M Caffrey, Wolfgang R Streit, John Webster, Kim M Handley, Ghasem H Salekdeh, Nicolas Tsesmetzis, Joao C Setubal, Phillip B Pope, Wen-Tso Liu, Adam R Rivers, Natalia N Ivanova, Nikos C Kyrpides
Viruses represent the most abundant life forms on the planet. Recent experimental and computational improvements have led to a dramatic increase in the number of viral genome sequences identified primarily from metagenomic samples. As a result of the expanding catalog of metagenomic viral sequences, there exists a need for a comprehensive computational platform integrating all these sequences with associated metadata and analytical tools. Here we present IMG/VR (https://img.jgi.doe.gov/vr/), the largest publicly available database of 3908 isolate reference DNA viruses with 264 413 computationally identified viral contigs from >6000 ecologically diverse metagenomic samples...
January 4, 2017: Nucleic Acids Research
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