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https://www.readbyqxmd.com/read/28527874/pressor-support-during-a-jarisch-herxheimer-reaction-after-initiation-of-treatment-for-weil-s-disease
#1
Randi Connor-Schuler, Anee Khan, Nikhil Goyal, Erin Zimny
We present a case of Weil's disease complicated by a Jarisch-Herxheimer reaction (JHR) after initiation of antibiotics while in the emergency department requiring invasive monitoring and vasopressor support. The case is followed by a brief review of the JHR which is rarely observed with treatment of leptospirosis. A healthy 28-year-old female who recently returned from the Caribbean presented to the emergency department with flu-like symptoms. The patient appeared jaundiced with conjunctival suffusion and was ultimately treated with the appropriate antibiotics for leptospirosis in the ED...
April 27, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28527673/minimal-access-surgery-compared-to-laparotomy-for-secondary-surgical-cytoreduction-in-patients-with-recurrent-ovarian-carcinoma-perioperative-and-oncologic-outcomes
#2
Ane Gerda Z Eriksson, Ashley Graul, Miao C Yu, Anthony Halko, Dennis S Chi, Oliver Zivanovic, Ginger J Gardner, Yukio Sonoda, Richard R Barakat, Nadeem R Abu-Rustum, Mario M Leitao
OBJECTIVES: To assess the perioperative outcomes of minimal access surgery (MAS) in secondary surgical cytoreduction (SSCR) for recurrent epithelial ovarian cancer (ROC); to compare oncologic outcomes with laparotomy (LAP). METHODS: Using an institutional database, we identified all patients with ROC undergoing SSCR from 1/5/09-6/14/14. Selection for MAS or LAP was based on surgeon preference. To minimize selection bias, preoperative imaging was reviewed for all LAP cases...
May 17, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28526204/the-786-t-c-polymorphism-of-nos3-gene-is-a-susceptibility-marker-of-copd-among-tunisians-that-correlates-with-nitric-oxide-levels-and-airflow-obstruction
#3
Hela Ben Nasr, Sarra Bchir, Amel Ben Anes, Asma Amri, Yosra Sakhana, Mohamed Benzarti, Abdelhamid Garrouch, Zouhair Tabka, Karim Chahed
OBJECTIVE: The goal of this study was to examine the role of G894T (rs1799983), -786T/C (rs3918161) and a 27 bp variable number of tandem repeats (VNTR) 4B/4A of NOS3 gene on the risk and severity of COPD. METHODS: The study included 194 controls and 138 COPD patients. NOS3 G894T, -786T/C and 4B/4A variants were determined by PCR analysis based on the banding pattern on gel electrophoresis. Pulmonary function was evaluated using body plethysmography. The levels of nitric oxide, peroxynitrite and lipid peroxides (T-BARS) were determined using spectrophotometric methods...
May 16, 2017: Cytokine
https://www.readbyqxmd.com/read/28521794/in-vitro-synthesis-of-9-10-dihydroxyhexadecanoic-acid-using-recombinant-escherichia-coli
#4
Anees Kaprakkaden, Preeti Srivastava, Virendra Swarup Bisaria
BACKGROUND: Hydroxy fatty acids are widely used in food, chemical and cosmetic industries. A variety of dihydroxy fatty acids have been synthesized so far; however, no studies have been done on the synthesis of 9,10-dihydroxyhexadecanoic acid. In the present study recombinant E. coli has been used for the heterologous expression of fatty acid hydroxylating enzymes and the whole cell lysate of the induced culture was used for in vitro production of 9,10-dihydroxyhexadecanoic acid. RESULTS: A first of its kind proof of principle has been successfully demonstrated for the production of 9,10-dihydroxyhexadecanoic acid using three different enzymes viz...
May 18, 2017: Microbial Cell Factories
https://www.readbyqxmd.com/read/28520088/clathrin-mediated-endocytosis-is-required-for-ane-30-100k-induced-autophagy
#5
Mei-Huei Lin, Young-Chau Liu, Shyun-Yeu Liu, Fang-Chi Chen, Pei-Jung Yang, Guan-Hua Li, Pang-Yen Liu, Ching-Yu Yen
BACKGROUND: We identified an autophagy-inducing areca nut (AN) ingredient (AIAI) in the 30-100 kDa fraction of AN extract (ANE 30-100K). This study was to analyze the role of endocytosis in ANE 30-100K-induced autophagy. METHODS: We used benzyl alcohol, dynasore, and shRNA of clathrin and dynamin to assess whether ANE 30-100K-induced cytotoxicity and accumulation of microtubule-associated protein 1 light chain 3 (LC3)-II were affected in oral (OECM-1) and esophageal (CE81T/VGH) carcinoma cells...
May 18, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28512604/traditional-dentistry-knowledge-among-serbs-in-several-balkan-countries
#6
Dragan V Ilic, Biljana Andjelski Radicevic, Anely Nedelcheva, Ivana Djurovic, Dejan Ostojic
BACKGROUND/AIM: There are still unrevealed treasures of traditional dental medicine, that is, the reason to investigate and present various ways in treatment of oral and orofacial tissues, as well as magic and religious elements involved in representative areas among Serbs. MATERIALS AND METHODS: Information was collected from the elderly non-professional folk dentists and herbalists with the additional help of local physicians and dentists that was done through questionnaire and personal interviews...
April 2017: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/28505968/inflammation-amyloid-and-atrophy-in-the-aging-brain-relationships-with-longitudinal-changes-in-cognition
#7
Roser Sala-Llonch, Ane-Victoria Idland, Tom Borza, Leiv Otto Watne, Torgeir Bruun Wyller, Anne Brækhus, Henrik Zetterberg, Kaj Blennow, Kristine Beate Walhovd, Anders Martin Fjell
Amyloid deposition occurs in aging, even in individuals free from cognitive symptoms, and is often interpreted as preclinical Alzheimer's disease (AD) pathophysiology. YKL-40 is a marker of neuroinflammation, being increased in AD, and hypothesized to interact with amyloid-β (Aβ) in causing cognitive decline early in the cascade of AD pathophysiology. Whether and how Aβ and YKL-40 affect brain and cognitive changes in cognitively healthy older adults is still unknown. We studied 89 participants (mean age: 73...
May 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28501267/gender-equity-imbalance-in-electrocardiology-a-call-to-action
#8
EDITORIAL
E Clarke Whalen, G Xu, I Cygankiewicz, L Bacharova, W Zareba, J S Steinberg, L G Tereshchenko, A Baranchuk
Despite the increasing number of women entering the medical profession, senior positions and academic productivity in many fields of medicine remain to be men dominated. We explored gender equity in electrocardiology as perceived by recent academic productivity and also active participation (presidencies and board constituents) in both the International Society of Electrocardiology (ISE) and the International Society for Holter and Noninvasive Electrocardiology (ISHNE). Academic productivity was measured by authorship (first and senior) in the Journal of Electrocardiology (JECG) and the Annals of Noninvasive Electrocardiology (ANE) in 2015...
May 4, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28501062/systemic-propolis-adjuvant-to-nonsurgical-periodontal-treatment-may-aid-in-glycemic-control-and-periodontal-health-in-type-2-diabetes-of-long-duration
#9
Wenche S Borgnakke
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Propolis improves periodontal status and glycemic control in patients with type 2 DM and chronic periodontitis: A randomized clinical trial. El-Sharkawy HM, Anees MM, Van Dyke TE. J Periodontol 2016;87:1418-1426. SOURCE OF FUNDING: Information not available. TYPE OF STUDY/DESIGN: Randomized controlled trial (RCT).
June 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28498172/effectiveness-of-patient-safety-leadership-walkrounds%C3%A2-on-patient-safety-culture-a-systematic-review-protocol
#10
Ane-Sofie Sølvtofte, Palle Larsen, Sussie Laustsen
The review objective is to synthesize the effect of Patient Safety Leadership WalkRounds (PSLWs) on patient safety culture (PSC).Specifically, the review question is: What is the effect of PSLWs on the PSC in hospitals, measured with validated surveys?
May 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28495686/incidence-of-non-pulmonary-cancer-and-lung-cancer-by-amount-of-emphysema-and-airway-wall-thickness-a-community-based-cohort
#11
Ane Aamli Gagnat, Miriam Gjerdevik, Frode Gallefoss, Harvey O Coxson, Amund Gulsvik, Per Bakke
There is limited knowledge about the prognostic value of quantitative computed tomography (CT) measures of emphysema and airway wall thickness in cancer.The aim of this study was to investigate if using CT to quantitatively assess the amount of emphysema and airway wall thickness independently predicts the subsequent incidence of non-pulmonary cancer and lung cancer.In the GenKOLS study of 2003-2005, 947 ever-smokers performed spirometry and underwent CT examination. The main predictors were the amount of emphysema measured by the percentage of low attenuation areas (%LAA) on CT and standardised measures of airway wall thickness (AWT-PI10)...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28492340/alterations-of-zinc-homeostasis-in-response-to-cryptococcus-neoformans-in-a-murine-macrophage-cell-line
#12
Francine Melise Dos Santos, Alícia Corbellini Piffer, Rafael de Oliveira Schneider, Nicole Sartori Ribeiro, Ane Wichine Acosta Garcia, Augusto Schrank, Lívia Kmetzsch, Marilene Henning Vainstein, Charley Christian Staats
AIM: To evaluate alterations of zinc homeostasis in macrophages exposed to Cryptococcus neoformans. Materials & methods: Using a fluorescent zinc probe-based flow cytometry and atomic absorption spectrometry, zinc levels were evaluated in J774.A1 cell lines exposed to C. neoformans H99 cells. The transcription profile of macrophage zinc related homeostasis genes - metallothioneins and zinc transporters (ZnTs) of the SLC30 and SLC39 (Zrt-Irt-protein) families - was analyzed by quantitative PCR...
May 11, 2017: Future Microbiology
https://www.readbyqxmd.com/read/28492062/intraoperative-injection-of-technetium-99m-sulfur-colloid-for-sentinel-lymph-node-biopsy-in-breast-cancer-patients-a-single-institution-experience
#13
Julian Berrocal, Lawrence Saperstein, Baiba Grube, Nina R Horowitz, Anees B Chagpar, Brigid K Killelea, Donald R Lannin
Background. Most institutions require a patient undergoing sentinel lymph node biopsy to go through nuclear medicine prior to surgery to be injected with radioisotope. This study describes the long-term results using intraoperative injection of radioisotope. Methods. Since late 2002, all patients undergoing a sentinel lymph node biopsy at the Yale-New Haven Breast Center underwent intraoperative injection of technetium-99m sulfur colloid. Endpoints included number of sentinel and nonsentinel lymph nodes obtained and number of positive sentinel and nonsentinel lymph nodes...
2017: Surgery Research and Practice
https://www.readbyqxmd.com/read/28492013/patient-and-practitioner-satisfaction-with-tele-dermatology-including-australia-s-indigenous-population-a-systematic-review-of-the-literature
#14
Emily K Kozera, Anes Yang, Dedee F Murrell
BACKGROUND: Australia's health disparity, combined with evolving technologies, has evoked increasing interest and funding in health services that could address inequities. One such emerging service is tele-medicine. OBJECTIVE: The purpose of this report is to discuss and evaluate the current literature regarding patient and practitioner satisfaction with tele-medicine, and more specifically tele-dermatology. METHODS: We searched for literature relevant to tele-dermatology use among Australia's indigenous population...
September 2016: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28491073/regulation-of-translation-by-tor-eif4e-and-eif2%C3%AE-in-plants-current-knowledge-challenges-and-future-perspectives
#15
REVIEW
Ane Sesma, Carmen Castresana, M Mar Castellano
An important step in eukaryotic gene expression is the synthesis of proteins from mRNA, a process classically divided into three stages, initiation, elongation, and termination. Translation is a precisely regulated and conserved process in eukaryotes. The presence of plant-specific translation initiation factors and the lack of well-known translational regulatory pathways in this kingdom nonetheless indicate how a globally conserved process can diversify among organisms. The control of protein translation is a central aspect of plant development and adaptation to environmental stress, but the mechanisms are still poorly understood...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28487311/egr2-and-3-control-adaptive-immune-responses-by-temporally-uncoupling-expansion-from-t-cell-differentiation
#16
Tizong Miao, Alistair L J Symonds, Randeep Singh, Janine D Symonds, Ane Ogbe, Becky Omodho, Bo Zhu, Suling Li, Ping Wang
Egr2 and 3 are important for maintaining immune homeostasis. Here we define a fundamental function of Egr2 and 3 operating as a checkpoint that controls the transition between clonal expansion and differentiation of effector T cells. Egr2 and 3 deficiency resulted in defective clonal expansion but hyperactivation and excessive differentiation of T cells in response to viral infection. Conversely, sustained Egr2 expression enhanced expansion but severely impaired effector differentiation. Egr2 bound to and controlled the expression of genes regulating proliferation (Myc and Myb) and differentiation repressors (Bcl6, Id3), while repressing transcription factors required for effector function (Zeb2, RORa, RORc, and Bhlhe40)...
May 9, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28469635/correction-platelet-rich-plasma-an-adjuvant-biological-therapy-to-assist-peripheral-nerve-repair
#17
Mikel Sánchez, Ane Garate, Diego Delgado, Sabino Padilla
[This corrects the article on p. 47 in vol. 12, PMID: 28250739.].
March 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28464403/seasonal-variation-in-child-mortality-in-rural-guinea-bissau
#18
Bibi Uhre Nielsen, Stine Byberg, Peter Aaby, Amabelia Rodrigues, Christine Stabell Benn, Ane Baerent Fisker
OBJECTIVES: In many African countries, child mortality is higher in the rainy season than in the dry season. We investigated the effect of season on child mortality by time periods, sex, and age in rural Guinea-Bissau. METHODS: Bandim health project follows children under-five in a health and demographic surveillance system in rural Guinea-Bissau. We compared the mortality in the rainy season (June to November) between 1990 and 2013 with the mortality in the dry season (December to May) in Cox proportional hazards models providing rainy versus dry season mortality rate ratios (r/d-mrr)...
May 2, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28462977/exposure-to-air-boosts-cuaac-reactions-catalyzed-by-peg-stabilized-cu-nanoparticles
#19
Fangyu Fu, Angel Martinez, Changlong Wang, Roberto Ciganda, Luis Yate, Ane Escobar, Sergio Moya, Eric Fouquet, Jaime Ruiz, Didier Astruc
New PEG-stabilized CuNP catalysts are designed upon Cu(ii) reduction with sodium naphthalenide in MeCN followed by simple purification using the salting-out effect. Their catalytic activity in CuAAC is boosted upon 30 min exposure to air, producing Cu2O NPs. These NPs are also supported on SBA-15, providing excellent recyclable heterogeneous catalysts that are applied in low amounts for efficient "click" functionalization.
May 11, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28461715/glutathione-in-plants-biosynthesis-and-physiological-role-in-environmental-stress-tolerance
#20
REVIEW
Mirza Hasanuzzaman, Kamrun Nahar, Taufika Islam Anee, Masayuki Fujita
Glutathione (GSH; γ-glutamyl-cysteinyl-glycine) is a small intracellular thiol molecule which is considered as a strong non-enzymatic antioxidant. Glutathione regulates multiple metabolic functions; for example, it protects membranes by maintaining the reduced state of both α-tocopherol and zeaxanthin, it prevents the oxidative denaturation of proteins under stress conditions by protecting their thiol groups, and it serves as a substrate for both glutathione peroxidase and glutathione S-transferase. By acting as a precursor of phytochelatins, GSH helps in the chelating of toxic metals/metalloids which are then transported and sequestered in the vacuole...
April 2017: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
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