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https://www.readbyqxmd.com/read/27933411/society-of-surgical-oncology-breast-disease-working-group-statement-on-prophylactic-risk-reducing-mastectomy
#1
Kelly K Hunt, David M Euhus, Judy C Boughey, Anees B Chagpar, Sheldon M Feldman, Nora M Hansen, Swati A Kulkarni, David R McCready, Eleftherios P Mamounas, Lee G Wilke, Kimberly J Van Zee, Monica Morrow
Over the past several years, there has been an increasing rate of bilateral prophylactic mastectomy (BPM) and contralateral prophylactic mastectomy (CPM) surgeries. Since publication of the 2007 SSO position statement on the use of risk-reducing mastectomy, there have been significant advances in the understanding of breast cancer biology and treatment. The purpose of this manuscript is to review the current literature as a resource to facilitate a shared and informed decision-making process regarding the use of risk-reducing mastectomy...
December 8, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27933203/maternal-inflammatory-bowel-disease-and-hypospadias-in-male-offspring-a-population-based-study-in-denmark
#2
Ane Birgitte Telén Andersen, Vera Ehrenstein, Rune Erichsen, Trine Frøslev, Henrik Toft Sørensen
BACKGROUND: The occurrence of inflammatory bowel disease (IBD) and hypospadias has been concurrently increasing, possibly through shared environmental risk factors such as endocrine disrupting compounds. Also, maternal IBD may disturb the normal development of the fetal reproductive tract. However, whether maternal IBD increases the risk of hypospadias in male offspring is unknown. We compared hypospadias risk in sons of mothers with and without IBD. METHODS: We used Danish nationwide population-based registries to conduct a longitudinal prevalence study including all live-born boys from 1979 through 2009...
2016: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/27927551/reliability-and-validity-testing-of-a-danish-translated-version-of%C3%A2-spinal%C3%A2-appearance-questionnaire-saq-v-1-1
#3
Ane Simony, Leah Y Carreon, Karen Hoejmark Hansen, Mikkel O Andersen
STUDY DESIGN: Cross-sectional. OBJECTIVE: To develop a psychometrically reliable and valid Danish version of the Spinal Appearance Questionnaire (SAQ). SUMMARY OF BACKGROUND DATA: The SAQ was developed as a disease-specific measure of quality of life in patients with adolescent idiopathic scoliosis (AIS), specifically for younger patients, as it has more visual cues than verbal questions. A reliable and valid Danish Version is not available...
March 2016: Spine Deformity
https://www.readbyqxmd.com/read/27916386/beneficial-effect-of-bilingualism-on-alzheimer-s-disease-csf-biomarkers-and-cognition
#4
Ainara Estanga, Mirian Ecay-Torres, Almudena Ibañez, Andrea Izagirre, Jorge Villanua, Maite Garcia-Sebastian, M Teresa Iglesias Gaspar, Ane Otaegui-Arrazola, Ane Iriondo, Monserrat Clerigue, Pablo Martinez-Lage
Bilingualism as a component of cognitive reserve has been claimed to delay the onset of Alzheimer's disease (AD). However, its effect on cerebrospinal fluid (CSF) AD-biomarkers has not been investigated. We assessed cognitive performance and CSF AD-biomarkers, and potential moderation effect of bilingualism on the association between age, CSF AD-biomarkers, and cognition. Cognitively healthy middle-aged participants classified as monolinguals (n = 100, nCSF = 59), early (n = 81, nCSF = 55) and late bilinguals (n = 97, nCSF = 52) were evaluated...
December 1, 2016: Neurobiology of Aging
https://www.readbyqxmd.com/read/27915125/artificial-neural-networks-as-a-powerful-numerical-tool-to-classify-specific-features-of-a-tooth-based-on-3d-scan-data
#5
Stefan Raith, Eric Per Vogel, Naeema Anees, Christine Keul, Jan-Frederik Güth, Daniel Edelhoff, Horst Fischer
Chairside manufacturing based on digital image acquisition is gainingincreasing importance in dentistry. For the standardized application of these methods, it is paramount to have highly automated digital workflows that can process acquired 3D image data of dental surfaces. Artificial Neural Networks (ANNs) arenumerical methods primarily used to mimic the complex networks of neural connections in the natural brain. Our hypothesis is that an ANNcan be developed that is capable of classifying dental cusps with sufficient accuracy...
November 27, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27907454/menopause-is-associated-with-accelerated-lung-function-decline
#6
Kai Triebner, Bobette Matulonga, Ane Johannessen, Sandra Suske, Bryndís Benediktsdóttir, Pascal Demoly, Shyamali C Dharmage, Karl A Franklin, Judith Garcia Aymerich, José Antonio Gullón Blanco, Joachim Heinrich, Mathias Holm, Debbie Jarvis, Rain Jõgi, Eva Lindberg, Jesús Martínez Moratalla Rovira, Nerea Muniozguren Agirre, Isabelle Pin, Nicole Probst-Hensch, Luca Puggini, Chantal Raherison, José Luis Sánchez-Ramos, Vivi Schlünssen, Jordi Sunyer, Cecilie Svanes, Steinar Hustad, Bénédicte Leynaert, Francisco Gómez Real
RATIONALE: Menopause is associated with changes in sex hormones, which affect immunity, inflammation, and osteoporosis and may impair lung function. Lung function decline has not previously been investigated in relation to menopause. OBJECTIVES: To study whether lung function decline, assessed by forced vital capacity and forced expiratory volume in one second, is accelerated in women who undergo menopause. METHODS: The population-based longitudinal European Community Respiratory Health Survey provided serum samples, spirometry and questionnaire data about respiratory and reproductive health from three study waves (N=1438)...
December 1, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27900177/high-intensity-interval-training-to-improve-fitness-in-children-with-cerebral-palsy
#7
Reidun Lauglo, Torstein Vik, Torarin Lamvik, Dorthe Stensvold, Ane-Kristine Finbråten, Trine Moholdt
AIM: To evaluate effects of high-intensity interval training (HIT) on aerobic exercise capacity, quality of life, and body composition in children with cerebral palsy (CP). METHODS: This was a baseline control trial. Children with CP, Gross Motor Function Classification System (GMFCS) levels I-IV, and age 10-17 years were included. The primary outcome, peak, and submaximum oxygen uptake (VO2peak, VO2submax) were measured at enrolment to the study (T0), after a pretraining period (T1), and after HIT (T2)...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27896888/response-of-narrow-qrs-tachycardia-to-late-coupled-pvc-what-is-the-mechanism
#8
Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Gurbhej Singh, Suji Karunakaran, Bharatraj Banavalikar, S P Abhilash, Anees Thajudeen, Ajitkumar Valaparambil
No abstract text is available yet for this article.
November 29, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/27890047/a-clear-urban-rural-gradient-of-allergic-rhinitis-in-a-population-based-study-in-northern-europe
#9
Stine Holmegaard Christensen, Signe Timm, Christer Janson, Bryndis Benediktsdóttir, Bertil Forsberg, Mathias Holm, Rain Jogi, Ane Johannessen, Ernst Omenaas, Torben Sigsgaard, Cecilie Svanes, Vivi Schlünssen
BACKGROUND: The protective effect of farm upbringing on allergic rhinitis is well known, but how upbringing in other environments influences the development of allergic rhinitis is scarcely investigated. The aim of this study was to investigate the association between place of upbringing and pet keeping in childhood and allergic rhinitis and nasal symptoms in adulthood. METHODS: The population-based Respiratory Health in Northern Europe study includes subjects from Denmark, Norway, Sweden, Iceland, and Estonia born in 1945-1973...
2016: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27882739/familial-acute-necrotizing-encephalopathy-without-ranbp2-mutation-poor-outcome
#10
Naoko Nishimura, Yoshihisa Higuchi, Nobusuke Kimura, Fumihito Nozaki, Tomohiro Kumada, Ai Hoshino, Makiko Saitoh, Masashi Mizuguchi
Most childhood cases of acute necrotizing encephalopathy (ANE) involve neither family history nor recurrence. ANE occasionally occurs, however, as a familial disorder or recurs in Caucasian patients. A mutation of RAN-binding protein 2 (RANBP2) has been discovered in more than one half of familial or recurrent ANE patients. In contrast, there has been no report of this mutation in East Asia. Here, we report the first sibling cases of typical ANE in Japan, with poor outcome. DNA analysis of genes associated with ANE or other encephalopathies, including RANBP2 and carnitine palmitoyl transferase II (CPT2), indicated neither mutations nor disease-related polymorphisms...
November 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27870256/factors-related-to-a-decline-in-upper-extremity-function-among-patients-with-a-wrist-fracture-due-to-a-fall
#11
Nerea González, Ane Antón-Ladislao, Miren Orive, Jon Zabala, Susana García-Gutiérrez, Carlota Las Hayas, Jose Maria Quintana
AIMS: The aim of this study was to identify factors related to a decline in function following a wrist fracture. METHODS: Observational, prospective cohort study done in five public hospitals of the Basque Health Service. We recruited adults aged 65 or older with a wrist fracture due to a fall who attended the emergency department (ED) of one of these hospitals. Sociodemographic and clinical data were collected, along with information about health-related quality of life (HRQoL) and functionality...
November 2016: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/27866869/clinical-characteristics-and-outcomes-of-yemeni-patients-with-acute-heart-failure-aged-50years-or-younger-data-from-gulf-acute-heart-failure-registry-gulf-care
#12
A-Nasser Munibari, Ahmed Al-Motarreb, Nora Al-Sagheer, Hana Abu Hadi, Ali Othman, Nawar Al-Wather, Abdu Hamoud, Mutae Alawlagy, Salem Almehdar, Abdulkarim Alhammadi, Mohammed Almogayed, Giorgio Caretta, Anees Al Jabri, Luciano Agati
AIMS: There is a shortage of data about acute heart failure (AHF) in the young, including its underlying causes, clinical presentation and outcomes. We aim to describe clinical characteristics, causes and outcomes of AHF in Yemeni patients aged 50years or younger. METHODS AND RESULTS: we evaluated Yemeni patients with AHF enrolled in Gulf CARE registry. Patients were divided into two groups: young patients (≤50years) and older patients (>50years). A total of 1536 patients with AHF were enrolled, of whom 635 (41...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27862033/narrow-qrs-tachycardia-in-a-patient-with-tachycardiomyopathy-what-is-the-mechanism
#13
Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Syamkumar Divakaramenon, Bharatraj Banavalikar, Abhilash S P, Anees Thajudeen, Ajitkumar Valaparambil
No abstract text is available yet for this article.
November 10, 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27858291/molecular-characterization-of-a-novel-ssrna-ourmia-like-virus-from-the-rice-blast-fungus-magnaporthe-oryzae
#14
Adriana Illana, Marco Marconi, Julio Rodríguez-Romero, Ping Xu, Tamas Dalmay, Mark D Wilkinson, Maria Ángeles Ayllón, Ane Sesma
In this study we characterize a novel positive and single stranded RNA (ssRNA) mycovirus isolated from the rice field isolate of Magnaporthe oryzae Guy11. The ssRNA contains a single open reading frame (ORF) of 2,373 nucleotides in length and encodes an RNA-dependent RNA polymerase (RdRp) closely related to ourmiaviruses (plant viruses) and ourmia-like mycoviruses. Accordingly, we name this virus Magnaporthe oryzae ourmia-like virus 1 (MOLV1). Although phylogenetic analysis suggests that MOLV1 is closely related to ourmia and ourmia-like viruses, it has some features never reported before within the Ourmiavirus genus...
November 17, 2016: Archives of Virology
https://www.readbyqxmd.com/read/27856947/is-diphtheria-tetanus-pertussis-dtp-associated-with-increased-female-mortality-a-meta-analysis-testing-the-hypotheses-of-sex-differential-non-specific-effects-of-dtp-vaccine
#15
Peter Aaby, Henrik Ravn, Ane B Fisker, Amabelia Rodrigues, Christine S Benn
BACKGROUND: Ten years ago, we formulated two hypotheses about whole-cell diphtheria-tetanus-pertussis (DTP) vaccination: first, when given after BCG, DTP increases mortality in girls and, second, following DTP there is an increase in the female/male mortality rate ratio (MRR). A recent review by WHO found no convincing evidence that DTP increases mortality in females. METHODS: We used previous DTP reviews as well as the recent WHO review for assessing the hypotheses...
November 17, 2016: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27856821/determinants-of-early-life-lung-function-in-african-infants
#16
Diane Gray, Lauren Willemse, Ane Visagie, Dorottya Czövek, Polite Nduru, Aneesa Vanker, Dan J Stein, Nastassja Koen, Peter D Sly, Zoltán Hantos, Graham L Hall, Heather J Zar
BACKGROUND: Low lung function in early life is associated with later respiratory illness. There is limited data on lung function in African infants despite a high prevalence of respiratory disease. AIM: To assess the determinants of early lung function in African infants. METHOD: Infants enrolled in a South African birth cohort, the Drakenstein child health study, had lung function measured at 6-10 weeks of age. Measurements, made with the infant breathing via a facemask during natural sleep, included tidal breathing, sulfur hexafluoride multiple breath washout and the forced oscillation technique...
November 17, 2016: Thorax
https://www.readbyqxmd.com/read/27856781/parental-rheumatoid-arthritis-and-childhood-epilepsy-a-nationwide-cohort-study
#17
Ane Lilleøre Rom, Chun Sen Wu, Jørn Olsen, Damini Jawaheer, Merete Lund Hetland, Jakob Christensen, Bent Ottesen, Lina Steinrud Mørch
OBJECTIVE: To assess the influence of parental rheumatoid arthritis (RA) on risk of epilepsy. METHODS: We performed a nationwide cohort study including all singletons born in Denmark from 1977 to 2008 (n = 1,917,723) through individual linkage to nationwide Danish registries. The children were followed for an average of 16 years. Main outcome measures were adjusted hazard ratios (HRs) for epilepsy with onset in early childhood (29 days-4 years), late childhood (5-15 years), adolescence/adulthood (≥15 years), and at any age until the end of follow-up (December 31, 2010)...
November 16, 2016: Neurology
https://www.readbyqxmd.com/read/27853454/comparative-analysis-of-secretomes-from-ectomycorrhizal-fungi-with-an-emphasis-on-small-secreted-proteins
#18
COMMENT
Kevin Garcia, Jean-Michel Ané
No abstract text is available yet for this article.
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27852494/reliability-and-validity-testing-of-a-danish-translated-version-of-the-scoliosis-research-society-instrument-22-revised-srs-22r
#19
Ane Simony, Leah Y Carreon, Mikkel O Andersen
STUDY DESIGN: Cross-sectional Objectives: To present a reliable and valid Danish translation of the Scoliosis Research Society-22R (SRS-22R). SUMMARY OF BACKGROUND DATA: The SRS22R was designed as a disease-specific measure of quality of life in surgically treated adolescent idiopathic scoliosis (AIS) patients. It has been translated and adapted into several languages. A reliable and valid Danish version is not available. METHODS: A Danish version of the SRS-22R was developed using previously published and widely accepted guidelines...
January 2016: Spine Deformity
https://www.readbyqxmd.com/read/27851781/characterization-of-a-novel-dermal-fibrosis-model-induced-by-areca-nut-extract-that-mimics-oral-submucous-fibrosis
#20
Min-Hsuan Chiang, Ping-Ho Chen, Yuk-Kwan Chen, Chia-Hsin Chen, Mei-Ling Ho, Yan-Hsiung Wang
Oral submucous fibrosis (OSF) is an oral potentially malignant disorder and areca quid chewing is the main etiological factor. However, the molecular mechanism underlying OSF remains unclear, partly due to the lack of an appropriate animal model. The present study aimed to establish and characterize an animal model of areca nut extract (ANE)-induced skin fibrosis that mimics OSF. Mice were divided into 4 groups: the control group; the bleomycin group; and the ANE10 and ANE20 groups, which received 10mg/ml and 20mg/ml subcutaneous (SC) injection of ANE, respectively...
2016: PloS One
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