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https://www.readbyqxmd.com/read/29760677/one-week-exposure-to-a-free-choice-high-fat-high-sugar-diet-does-not-interfere-with-the-lipopolysaccharide-induced-acute-phase-response-in-the-hypothalamus-of-male-rats
#1
Evita Belegri, Leslie Eggels, Susanne E la Fleur, Anita Boelen
Obesity has been associated with increased susceptibility to infection in humans and rodents. Obesity is also associated with low-grade hypothalamic inflammation that depends not only on body weight but also on diet. In the present study, we investigated if the bacterial endotoxin [lipopolysaccharide (LPS)]-induced acute phase response is aggravated in rats on a 1-week free-choice high-fat high-sugar (fcHFHS) diet and explained by diet-induced hypothalamic inflammation. Male Wistar rats were on an fcHFHS diet or chow for 1 week and afterwards intraperitoneally injected with LPS or saline...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29756910/search-for-high-mass-resonances-decaying-to-%C3%AF-%C3%AE-in-pp-collisions-at-sqrt-s-13-tev-with-the-atlas-detector
#2
M Aaboud, G Aad, B Abbott, O Abdinov, B Abeloos, S H Abidi, O S AbouZeid, N L Abraham, H Abramowicz, H Abreu, Y Abulaiti, B S Acharya, S Adachi, L Adamczyk, J Adelman, M Adersberger, T Adye, A A Affolder, Y Afik, C Agheorghiesei, J A Aguilar-Saavedra, S P Ahlen, F Ahmadov, G Aielli, S Akatsuka, T P A Åkesson, E Akilli, A V Akimov, G L Alberghi, J Albert, P Albicocco, M J Alconada Verzini, S Alderweireldt, M Aleksa, I N Aleksandrov, C Alexa, G Alexander, T Alexopoulos, M Alhroob, B Ali, M Aliev, G Alimonti, J Alison, S P Alkire, C Allaire, B M M Allbrooke, B W Allen, P P Allport, A Aloisio, A Alonso, F Alonso, C Alpigiani, A A Alshehri, M I Alstaty, B Alvarez Gonzalez, D Álvarez Piqueras, M G Alviggi, B T Amadio, Y Amaral Coutinho, L Ambroz, C Amelung, D Amidei, S P Amor Dos Santos, S Amoroso, C S Amrouche, C Anastopoulos, L S Ancu, N Andari, T Andeen, C F Anders, J K Anders, K J Anderson, A Andreazza, V Andrei, S Angelidakis, I Angelozzi, A Angerami, A V Anisenkov, A Annovi, C Antel, M T Anthony, M Antonelli, D J Antrim, F Anulli, M Aoki, L Aperio Bella, G Arabidze, Y Arai, J P Araque, V Araujo Ferraz, R Araujo Pereira, A T H Arce, R E Ardell, F A Arduh, J-F Arguin, S Argyropoulos, A J Armbruster, L J Armitage, O Arnaez, H Arnold, M Arratia, O Arslan, A Artamonov, G Artoni, S Artz, S Asai, N Asbah, A Ashkenazi, E M Asimakopoulou, L Asquith, K Assamagan, R Astalos, R J Atkin, M Atkinson, N B Atlay, K Augsten, G Avolio, R Avramidou, B Axen, M K Ayoub, G Azuelos, A E Baas, M J Baca, H Bachacou, K Bachas, M Backes, P Bagnaia, M Bahmani, H Bahrasemani, J T Baines, M Bajic, O K Baker, P J Bakker, D Bakshi Gupta, E M Baldin, P Balek, F Balli, W K Balunas, E Banas, A Bandyopadhyay, Sw Banerjee, A A E Bannoura, L Barak, W M Barbe, E L Barberio, D Barberis, M Barbero, T Barillari, M-S Barisits, J T Barkeloo, T Barklow, N Barlow, R Barnea, S L Barnes, B M Barnett, R M Barnett, Z Barnovska-Blenessy, A Baroncelli, G Barone, A J Barr, L Barranco Navarro, F Barreiro, J Barreiro Guimarães da Costa, R Bartoldus, A E Barton, P Bartos, A Basalaev, A Bassalat, R L Bates, S J Batista, J R Batley, M Battaglia, M Bauce, F Bauer, K T Bauer, H S Bawa, J B Beacham, M D Beattie, T Beau, P H Beauchemin, P Bechtle, H P Beck, H C Beck, K Becker, M Becker, C Becot, A J Beddall, A Beddall, V A Bednyakov, M Bedognetti, C P Bee, T A Beermann, M Begalli, M Begel, A Behera, J K Behr, A S Bell, G Bella, L Bellagamba, A Bellerive, M Bellomo, K Belotskiy, N L Belyaev, O Benary, D Benchekroun, M Bender, N Benekos, Y Benhammou, E Benhar Noccioli, J Benitez, D P Benjamin, M Benoit, J R Bensinger, S Bentvelsen, L Beresford, M Beretta, D Berge, E Bergeaas Kuutmann, N Berger, L J Bergsten, J Beringer, S Berlendis, N R Bernard, G Bernardi, C Bernius, F U Bernlochner, T Berry, P Berta, C Bertella, G Bertoli, I A Bertram, C Bertsche, G J Besjes, O Bessidskaia Bylund, M Bessner, N Besson, A Bethani, S Bethke, A Betti, A J Bevan, J Beyer, R M Bianchi, O Biebel, D Biedermann, R Bielski, K 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F Cirotto, Z H Citron, M Citterio, A Clark, M R Clark, P J Clark, R N Clarke, C Clement, Y Coadou, M Cobal, A Coccaro, J Cochran, L Colasurdo, B Cole, A P Colijn, J Collot, P Conde Muiño, E Coniavitis, S H Connell, I A Connelly, S Constantinescu, F Conventi, A M Cooper-Sarkar, F Cormier, K J R Cormier, M Corradi, E E Corrigan, F Corriveau, A Cortes-Gonzalez, M J Costa, D Costanzo, G Cottin, G Cowan, B E Cox, J Crane, K Cranmer, S J Crawley, R A Creager, G Cree, S Crépé-Renaudin, F Crescioli, M Cristinziani, V Croft, G Crosetti, A Cueto, T Cuhadar Donszelmann, A R Cukierman, M Curatolo, J Cúth, S Czekierda, P Czodrowski, G D'amen, S D'Auria, L D'eramo, M D'Onofrio, M J Da Cunha Sargedas De Sousa, C Da Via, W Dabrowski, T Dado, S Dahbi, T Dai, O Dale, F Dallaire, C Dallapiccola, M Dam, J R Dandoy, M F Daneri, N P Dang, N S Dann, M Danninger, V Dao, G Darbo, S Darmora, O Dartsi, A Dattagupta, T Daubney, W Davey, C David, T Davidek, D R Davis, E Dawe, I Dawson, K De, R de Asmundis, A De Benedetti, S De Castro, S De Cecco, N De Groot, P de Jong, H De la Torre, F De Lorenzi, A De Maria, D De Pedis, A De Salvo, U De Sanctis, A De Santo, K De Vasconcelos Corga, J B De Vivie De Regie, C Debenedetti, D V Dedovich, N Dehghanian, M Del Gaudio, J Del Peso, D Delgove, F Deliot, C M Delitzsch, A Dell'Acqua, L Dell'Asta, M Della Pietra, D Della Volpe, M Delmastro, C Delporte, P A Delsart, D A DeMarco, S Demers, M Demichev, S P Denisov, D Denysiuk, D Derendarz, J E Derkaoui, F Derue, P Dervan, K Desch, C Deterre, K Dette, M R Devesa, P O Deviveiros, A Dewhurst, S Dhaliwal, F A Di Bello, A Di Ciaccio, L Di Ciaccio, W K Di Clemente, C Di Donato, A Di Girolamo, B Di Micco, R Di Nardo, K F Di Petrillo, A Di Simone, R Di Sipio, D Di Valentino, C Diaconu, M Diamond, F A Dias, T Dias do Vale, M A Diaz, J Dickinson, E B Diehl, J Dietrich, S Díez Cornell, A Dimitrievska, J Dingfelder, F Dittus, F Djama, T Djobava, J I Djuvsland, M A B do Vale, M Dobre, D Dodsworth, C Doglioni, J Dolejsi, Z Dolezal, M Donadelli, J Donini, J Dopke, A Doria, M T Dova, A T Doyle, E Drechsler, E Dreyer, T Dreyer, M Dris, Y Du, J Duarte-Campderros, F Dubinin, A Dubreuil, E Duchovni, G Duckeck, A Ducourthial, O A Ducu, D Duda, A Dudarev, A Chr Dudder, E M Duffield, L Duflot, M Dührssen, C Dulsen, M Dumancic, A E Dumitriu, A K Duncan, M Dunford, A Duperrin, H Duran Yildiz, M Düren, A Durglishvili, D Duschinger, B Dutta, D Duvnjak, M Dyndal, B S Dziedzic, C Eckardt, K M Ecker, R C Edgar, T Eifert, G Eigen, K Einsweiler, T Ekelof, M El Kacimi, R El Kosseifi, V Ellajosyula, M Ellert, F Ellinghaus, A A Elliot, N Ellis, J Elmsheuser, M Elsing, D Emeliyanov, Y Enari, J S Ennis, M B Epland, J Erdmann, A Ereditato, S Errede, M Escalier, C Escobar, B Esposito, O Estrada Pastor, A I Etienvre, E Etzion, H Evans, A Ezhilov, M Ezzi, F Fabbri, L Fabbri, V Fabiani, G Facini, R M Fakhrutdinov, S Falciano, P J Falke, S Falke, J Faltova, Y Fang, M Fanti, A Farbin, A Farilla, E M Farina, T Farooque, S Farrell, S M Farrington, P Farthouat, F Fassi, P Fassnacht, D Fassouliotis, M Faucci Giannelli, A Favareto, W J Fawcett, L Fayard, O L Fedin, W Fedorko, M Feickert, S Feigl, L Feligioni, C Feng, E J Feng, M Feng, M J Fenton, A B Fenyuk, L Feremenga, J Ferrando, A Ferrari, P Ferrari, R Ferrari, D E Ferreira de Lima, A Ferrer, D Ferrere, C Ferretti, F Fiedler, A Filipčič, F Filthaut, M Fincke-Keeler, K D Finelli, M C N Fiolhais, L Fiorini, C Fischer, J Fischer, W C Fisher, N Flaschel, I Fleck, P Fleischmann, R R M Fletcher, T Flick, B M Flierl, L M Flores, L R Flores Castillo, N Fomin, G T Forcolin, A Formica, F A Förster, A Forti, A G Foster, D Fournier, H Fox, S Fracchia, P Francavilla, M Franchini, S Franchino, D Francis, L Franconi, M Franklin, M Frate, M Fraternali, D Freeborn, S M Fressard-Batraneanu, B Freund, W S Freund, D Froidevaux, J A Frost, C Fukunaga, T Fusayasu, J Fuster, O Gabizon, A Gabrielli, A Gabrielli, G P Gach, S Gadatsch, S Gadomski, P Gadow, G Gagliardi, L G Gagnon, C Galea, B Galhardo, E J Gallas, B J Gallop, P Gallus, G Galster, R Gamboa Goni, K K Gan, S Ganguly, Y Gao, Y S Gao, F M Garay Walls, C García, J E García Navarro, J A García Pascual, M Garcia-Sciveres, R W Gardner, N Garelli, V Garonne, K Gasnikova, A Gaudiello, G Gaudio, I L Gavrilenko, A Gavrilyuk, C Gay, G Gaycken, E N Gazis, C N P Gee, J Geisen, M Geisen, M P Geisler, K Gellerstedt, C Gemme, M H Genest, C Geng, S Gentile, C Gentsos, S George, D Gerbaudo, G Geßner, S Ghasemi, M Ghneimat, B Giacobbe, S Giagu, N Giangiacomi, P Giannetti, S M Gibson, M Gignac, D Gillberg, G Gilles, D M Gingrich, M P Giordani, F M Giorgi, P F Giraud, P Giromini, G Giugliarelli, D Giugni, F Giuli, M Giulini, S Gkaitatzis, I Gkialas, E L Gkougkousis, P Gkountoumis, L K Gladilin, C Glasman, J Glatzer, P C F Glaysher, A Glazov, M Goblirsch-Kolb, J Godlewski, S Goldfarb, T Golling, D Golubkov, A Gomes, R Gonçalo, R Goncalves Gama, G Gonella, L Gonella, A Gongadze, F Gonnella, J L Gonski, S González de la Hoz, S 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Kourlitis, V Kouskoura, A B Kowalewska, R Kowalewski, T Z Kowalski, C Kozakai, W Kozanecki, A S Kozhin, V A Kramarenko, G Kramberger, D Krasnopevtsev, M W Krasny, A Krasznahorkay, D Krauss, J A Kremer, J Kretzschmar, K Kreutzfeldt, P Krieger, K Krizka, K Kroeninger, H Kroha, J Kroll, J Kroll, J Kroseberg, J Krstic, U Kruchonak, H Krüger, N Krumnack, M C Kruse, T Kubota, S Kuday, J T Kuechler, S Kuehn, A Kugel, F Kuger, T Kuhl, V Kukhtin, R Kukla, Y Kulchitsky, S Kuleshov, Y P Kulinich, M Kuna, T Kunigo, A Kupco, T Kupfer, O Kuprash, H Kurashige, L L Kurchaninov, Y A Kurochkin, M G Kurth, E S Kuwertz, M Kuze, J Kvita, T Kwan, A La Rosa, J L La Rosa Navarro, L La Rotonda, F La Ruffa, C Lacasta, F Lacava, J Lacey, D P J Lack, H Lacker, D Lacour, E Ladygin, R Lafaye, B Laforge, S Lai, S Lammers, W Lampl, E Lançon, U Landgraf, M P J Landon, M C Lanfermann, V S Lang, J C Lange, R J Langenberg, A J Lankford, F Lanni, K Lantzsch, A Lanza, A Lapertosa, S Laplace, J F Laporte, T Lari, F Lasagni 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Marchese, G Marchiori, M Marcisovsky, C A Marin Tobon, M Marjanovic, D E Marley, F Marroquim, Z Marshall, M U F Martensson, S Marti-Garcia, C B Martin, T A Martin, V J Martin, B Martin Dit Latour, M Martinez, V I Martinez Outschoorn, S Martin-Haugh, V S Martoiu, A C Martyniuk, A Marzin, L Masetti, T Mashimo, R Mashinistov, J Masik, A L Maslennikov, L H Mason, L Massa, P Mastrandrea, A Mastroberardino, T Masubuchi, P Mättig, J Maurer, S J Maxfield, D A Maximov, R Mazini, I Maznas, S M Mazza, N C Mc Fadden, G Mc Goldrick, S P Mc Kee, A McCarn, T G McCarthy, L I McClymont, E F McDonald, J A Mcfayden, G Mchedlidze, M A McKay, K D McLean, S J McMahon, P C McNamara, C J McNicol, R A McPherson, Z A Meadows, S Meehan, T J Megy, S Mehlhase, A Mehta, T Meideck, K Meier, B Meirose, D Melini, B R Mellado Garcia, J D Mellenthin, M Melo, F Meloni, A Melzer, S B Menary, L Meng, X T Meng, A Mengarelli, S Menke, E Meoni, S Mergelmeyer, C Merlassino, P Mermod, L Merola, C Meroni, F S Merritt, A Messina, J Metcalfe, A S Mete, C Meyer, J-P Meyer, J Meyer, H Meyer Zu Theenhausen, F Miano, R P Middleton, L Mijović, G Mikenberg, M Mikestikova, M Mikuž, M Milesi, A Milic, D A Millar, D W Miller, A Milov, D A Milstead, A A Minaenko, I A Minashvili, A I Mincer, B Mindur, M Mineev, Y Minegishi, Y Ming, L M Mir, A Mirto, K P Mistry, T Mitani, J Mitrevski, V A Mitsou, A Miucci, P S Miyagawa, A Mizukami, J U Mjörnmark, T Mkrtchyan, M Mlynarikova, T Moa, K Mochizuki, P Mogg, S Mohapatra, S Molander, R Moles-Valls, M C Mondragon, K Mönig, J Monk, E Monnier, A Montalbano, J Montejo Berlingen, F Monticelli, S Monzani, R W Moore, N Morange, D Moreno, M Moreno Llácer, P Morettini, M Morgenstern, S Morgenstern, D Mori, T Mori, M Morii, M Morinaga, V Morisbak, A K Morley, G Mornacchi, J D Morris, L Morvaj, P Moschovakos, M Mosidze, H J Moss, J Moss, K Motohashi, R Mount, E Mountricha, E J W Moyse, S Muanza, F Mueller, J Mueller, R S P Mueller, D Muenstermann, P Mullen, G A Mullier, F J Munoz Sanchez, P 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Ocariz, A Ochi, I Ochoa, J P Ochoa-Ricoux, S Oda, S Odaka, A Oh, S H Oh, C C Ohm, H Ohman, H Oide, H Okawa, Y Okazaki, Y Okumura, T Okuyama, A Olariu, L F Oleiro Seabra, S A Olivares Pino, D Oliveira Damazio, J L Oliver, M J R Olsson, A Olszewski, J Olszowska, A Onofre, K Onogi, P U E Onyisi, H Oppen, M J Oreglia, Y Oren, D Orestano, E C Orgill, N Orlando, R S Orr, B Osculati, R Ospanov, G Otero Y Garzon, H Otono, M Ouchrif, F Ould-Saada, A Ouraou, K P Oussoren, Q Ouyang, M Owen, R E Owen, V E Ozcan, N Ozturk, K Pachal, A Pacheco Pages, L Pacheco Rodriguez, C Padilla Aranda, S Pagan Griso, M Paganini, F Paige, G Palacino, S Palazzo, S Palestini, M Palka, D Pallin, I Panagoulias, C E Pandini, J G Panduro Vazquez, P Pani, L Paolozzi, Th D Papadopoulou, K Papageorgiou, A Paramonov, D Paredes Hernandez, B Parida, A J Parker, M A Parker, K A Parker, F Parodi, J A Parsons, U Parzefall, V R Pascuzzi, J M Pasner, E Pasqualucci, S Passaggio, Fr Pastore, P Pasuwan, S Pataraia, J R Pater, A 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Proklova, K Prokofiev, F Prokoshin, S Protopopescu, J Proudfoot, M Przybycien, A Puri, P Puzo, J Qian, Y Qin, A Quadt, M Queitsch-Maitland, A Qureshi, S K Radhakrishnan, P Rados, F Ragusa, G Rahal, J A Raine, S Rajagopalan, T Rashid, S Raspopov, M G Ratti, D M Rauch, F Rauscher, S Rave, B Ravina, I Ravinovich, J H Rawling, M Raymond, A L Read, N P Readioff, M Reale, D M Rebuzzi, A Redelbach, G Redlinger, R Reece, R G Reed, K Reeves, L Rehnisch, J Reichert, A Reiss, C Rembser, H Ren, M Rescigno, S Resconi, E D Resseguie, S Rettie, E Reynolds, O L Rezanova, P Reznicek, R Richter, S Richter, E Richter-Was, O Ricken, M Ridel, P Rieck, C J Riegel, O Rifki, M Rijssenbeek, A Rimoldi, M Rimoldi, L Rinaldi, G Ripellino, B Ristić, E Ritsch, I Riu, J C Rivera Vergara, F Rizatdinova, E Rizvi, C Rizzi, R T Roberts, S H Robertson, A Robichaud-Veronneau, D Robinson, J E M Robinson, A Robson, E Rocco, C Roda, Y Rodina, S Rodriguez Bosca, A Rodriguez Perez, D Rodriguez Rodriguez, A M Rodríguez Vera, S 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Sapronov, J G Saraiva, O Sasaki, K Sato, E Sauvan, P Savard, N Savic, R Sawada, C Sawyer, L Sawyer, C Sbarra, A Sbrizzi, T Scanlon, D A Scannicchio, J Schaarschmidt, P Schacht, B M Schachtner, D Schaefer, L Schaefer, J Schaeffer, S Schaepe, U Schäfer, A C Schaffer, D Schaile, R D Schamberger, V A Schegelsky, D Scheirich, F Schenck, M Schernau, C Schiavi, S Schier, L K Schildgen, Z M Schillaci, E J Schioppa, M Schioppa, K E Schleicher, S Schlenker, K R Schmidt-Sommerfeld, K Schmieden, C Schmitt, S Schmitt, S Schmitz, U Schnoor, L Schoeffel, A Schoening, E Schopf, M Schott, J F P Schouwenberg, J Schovancova, S Schramm, N Schuh, A Schulte, H-C Schultz-Coulon, M Schumacher, B A Schumm, Ph Schune, A Schwartzman, T A Schwarz, H Schweiger, Ph Schwemling, R Schwienhorst, J Schwindling, A Sciandra, G Sciolla, M Scornajenghi, F Scuri, F Scutti, L M Scyboz, J Searcy, C D Sebastiani, P Seema, S C Seidel, A Seiden, J M Seixas, G Sekhniaidze, K Sekhon, S J Sekula, N Semprini-Cesari, S Senkin, C 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Sobie, F Socher, A M Soffa, A Soffer, A Søgaard, D A Soh, G Sokhrannyi, C A Solans Sanchez, M Solar, E Yu Soldatov, U Soldevila, A A Solodkov, A Soloshenko, O V Solovyanov, V Solovyev, P Sommer, H Son, W Song, A Sopczak, F Sopkova, D Sosa, C L Sotiropoulou, S Sottocornola, R Soualah, A M Soukharev, D South, B C Sowden, S Spagnolo, M Spalla, M Spangenberg, F Spanò, D Sperlich, F Spettel, T M Spieker, R Spighi, G Spigo, L A Spiller, M Spousta, A Stabile, R Stamen, S Stamm, E Stanecka, R W Stanek, C Stanescu, M M Stanitzki, B S Stapf, S Stapnes, E A Starchenko, G H Stark, J Stark, S H Stark, P Staroba, P Starovoitov, S Stärz, R Staszewski, M Stegler, P Steinberg, B Stelzer, H J Stelzer, O Stelzer-Chilton, H Stenzel, T J Stevenson, G A Stewart, M C Stockton, G Stoicea, P Stolte, S Stonjek, A Straessner, J Strandberg, S Strandberg, M Strauss, P Strizenec, R Ströhmer, D M Strom, R Stroynowski, A Strubig, S A Stucci, B Stugu, J Stupak, N A Styles, D Su, J Su, S Suchek, Y Sugaya, M Suk, V V 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Tokár, K Tokushuku, E Tolley, M Tomoto, L Tompkins, K Toms, B Tong, P Tornambe, E Torrence, H Torres, E Torró Pastor, C Tosciri, J Toth, F Touchard, D R Tovey, C J Treado, T Trefzger, F Tresoldi, A Tricoli, I M Trigger, S Trincaz-Duvoid, M F Tripiana, W Trischuk, B Trocmé, A Trofymov, C Troncon, M Trovatelli, F Trovato, L Truong, M Trzebinski, A Trzupek, F Tsai, K W Tsang, J C-L Tseng, P V Tsiareshka, N Tsirintanis, S Tsiskaridze, V Tsiskaridze, E G Tskhadadze, I I Tsukerman, V Tsulaia, S Tsuno, D Tsybychev, Y Tu, A Tudorache, V Tudorache, T T Tulbure, A N Tuna, S Turchikhin, D Turgeman, I Turk Cakir, R Turra, P M Tuts, G Ucchielli, I Ueda, M Ughetto, F Ukegawa, G Unal, A Undrus, G Unel, F C Ungaro, Y Unno, K Uno, J Urban, P Urquijo, P Urrejola, G Usai, J Usui, L Vacavant, V Vacek, B Vachon, K O H Vadla, A Vaidya, C Valderanis, E Valdes Santurio, M Valente, S Valentinetti, A Valero, L Valéry, R A Vallance, A Vallier, J A Valls Ferrer, T R Van Daalen, W Van Den Wollenberg, H van der 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Wang, H Wang, H Wang, J Wang, J Wang, Q Wang, R-J Wang, R Wang, R Wang, S M Wang, T Wang, W Wang, W Wang, Y Wang, Z Wang, C Wanotayaroj, A Warburton, C P Ward, D R Wardrope, A Washbrook, P M Watkins, A T Watson, M F Watson, G Watts, S Watts, B M Waugh, A F Webb, S Webb, C Weber, M S Weber, S M Weber, S A Weber, J S Webster, A R Weidberg, B Weinert, J Weingarten, M Weirich, C Weiser, P S Wells, T Wenaus, T Wengler, S Wenig, N Wermes, M D Werner, P Werner, M Wessels, T D Weston, K Whalen, N L Whallon, A M Wharton, A S White, A White, M J White, R White, D Whiteson, B W Whitmore, F J Wickens, W Wiedenmann, M Wielers, C Wiglesworth, L A M Wiik-Fuchs, A Wildauer, F Wilk, H G Wilkens, H H Williams, S Williams, C Willis, S Willocq, J A Wilson, I Wingerter-Seez, E Winkels, F Winklmeier, O J Winston, B T Winter, M Wittgen, M Wobisch, A Wolf, T M H Wolf, R Wolff, M W Wolter, H Wolters, V W S Wong, N L Woods, S D Worm, B K Wosiek, K W Wozniak, K Wraight, M Wu, S L Wu, X Wu, Y Wu, T R Wyatt, B M Wynne, S Xella, Z Xi, L Xia, D Xu, H Xu, L Xu, T Xu, W Xu, B Yabsley, S Yacoob, K Yajima, D P Yallup, D Yamaguchi, Y Yamaguchi, A Yamamoto, T Yamanaka, F Yamane, M Yamatani, T Yamazaki, Y Yamazaki, Z Yan, H Yang, H Yang, S Yang, Y Yang, Y Yang, Z Yang, W-M Yao, Y C Yap, Y Yasu, E Yatsenko, K H Yau Wong, J Ye, S Ye, I Yeletskikh, E Yigitbasi, E Yildirim, K Yorita, K Yoshihara, C Young, C J S Young, J Yu, J Yu, X Yue, S P Y Yuen, I Yusuff, B Zabinski, G Zacharis, R Zaidan, A M Zaitsev, N Zakharchuk, J Zalieckas, S Zambito, D Zanzi, C Zeitnitz, G Zemaityte, J C Zeng, Q Zeng, O Zenin, T Ženiš, D Zerwas, M Zgubič, D Zhang, D Zhang, F Zhang, G Zhang, H Zhang, J Zhang, L Zhang, L Zhang, M Zhang, P Zhang, R Zhang, R Zhang, X Zhang, Y Zhang, Z Zhang, X Zhao, Y Zhao, Z Zhao, A Zhemchugov, B Zhou, C Zhou, L Zhou, M Zhou, M Zhou, N Zhou, Y Zhou, C G Zhu, H Zhu, H Zhu, J Zhu, Y Zhu, X Zhuang, K Zhukov, V Zhulanov, A Zibell, D Zieminska, N I Zimine, S Zimmermann, Z Zinonos, M Zinser, M Ziolkowski, L Živković, G Zobernig, A Zoccoli, K Zoch, T G Zorbas, R Zou, M Zur Nedden, L Zwalinski
A search for high-mass resonances decaying to τν using proton-proton collisions at sqrt[s]=13  TeV produced by the Large Hadron Collider is presented. Only τ-lepton decays with hadrons in the final state are considered. The data were recorded with the ATLAS detector and correspond to an integrated luminosity of 36.1  fb^{-1}. No statistically significant excess above the standard model expectation is observed; model-independent upper limits are set on the visible τν production cross section. Heavy W^{'} bosons with masses less than 3...
April 20, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29749029/rac1-muscle-knockout-exacerbates-the-detrimental-effect-of-high-fat-diet-on-insulin-stimulated-muscle-glucose-uptake-independently-of-akt
#3
Steffen H Raun, Mona Ali, Rasmus Kjøbsted, Lisbeth L V Møller, Morten A Federspiel, Erik A Richter, Thomas E Jensen, Lykke Sylow
KEY POINTS: The actin cytoskeleton regulating GTPase, Rac1, is a novel player in insulin-stimulated glucose uptake in muscle in vivo. High-fat diet (HFD) exacerbates muscle insulin resistance in Rac1 muscle knockout (mKO) mice. Muscle Rac1 KO protects against HFD-induced insulin resistance in fat tissue indicating tissue cross-talk. A fatty diet markedly reduces insulin clearance in mice. ABSTRACT: Insulin resistance and perturbations in glucose metabolism underpin common lifestyle diseases such as type 2 diabetes and obesity...
May 10, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29748206/deep-learning-convolutional-neural-networks-accurately-classify-genetic-mutations-in-gliomas
#4
P Chang, J Grinband, B D Weinberg, M Bardis, M Khy, G Cadena, M-Y Su, S Cha, C G Filippi, D Bota, P Baldi, L M Poisson, R Jain, D Chow
BACKGROUND AND PURPOSE: The World Health Organization has recently placed new emphasis on the integration of genetic information for gliomas. While tissue sampling remains the criterion standard, noninvasive imaging techniques may provide complimentary insight into clinically relevant genetic mutations. Our aim was to train a convolutional neural network to independently predict underlying molecular genetic mutation status in gliomas with high accuracy and identify the most predictive imaging features for each mutation...
May 10, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29741665/evaluation-of-prep-eligibility-criteria-using-sexually-transmissible-infections-as-hiv-risk-markers-at-enrolment-in-prepx-a-large-australian-hiv-pre-exposure-prophylaxis-trial
#5
Vincent J Cornelisse, Christopher K Fairley, Mark Stoove, Jason Asselin, Eric P F Chow, Brian Price, Norman J Roth, Jeff Willcox, B K Tee, Matthew Penn, Christina C Chang, Judith Armishaw, George Forgan-Smith, Edwina J Wright
Background: The PrEPX trial provided HIV pre-exposure prophylaxis (PrEP) to 2600 people in Victoria, Australia. To determine participants' HIV risk, PrEPX used six eligibility criteria derived from the Australian PrEP guidelines, based on the CDC PrEP guidelines. Participants who fulfilled no eligibility criteria could be enrolled if clinically assessed to need PrEP. This study evaluated whether PREPX eligibility criteria correlated with biological HIV risk markers, namely syphilis, anorectal chlamydia or anorectal gonorrhoea (STIs)...
May 7, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29729257/association-between-bacteremia-from-specific-microbes-and-subsequent-diagnosis-of-colorectal-cancer
#6
Thomas N Y Kwong, Xiansong Wang, Geicho Nakatsu, Tai Cheong Chow, Timothy Tipoe, Rudin Z W Dai, Kelvin K K Tsoi, Martin C S Wong, Gary Tse, Matthew T V Chan, Francis K L Chan, Siew C Ng, Justin C Y Wu, William K K Wu, Jun Yu, Joseph J Y Sung, Sunny H Wong
BACKGROUND & AIMS: Colorectal cancer (CRC) development has been associated with increased proportions of Bacteroides fragilis and certain Streptococcus, Fusobacterium, and Peptostreptococcus species in the intestinal microbiota. We investigated associations between bacteremia from specific intestinal microbes and occurrence of CRC. METHODS: We performed a retrospective study, collecting data from13,096 adult patients (exposed group) in Hong Kong hospitalized with bacteremia (identified by blood culture test), without a previous diagnosis of cancer, from January 1, 2006 through December 31, 2015...
May 2, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29726984/immune-cell-census-in-murine-atherosclerosis-cytometry-by-time-of-flight-illuminates-vascular-myeloid-cell-diversity
#7
Jennifer E Cole, Inhye Park, David Ahern, Christina Kassiteridi, Dina Danso Abeam, Michael Goddard, Patricia Green, Pasquale Maffia, Claudia Monaco
Aims: Atherosclerosis is characterised by the abundant infiltration of myeloid cells starting at early stages of disease. Myeloid cells are key players in vascular immunity during atherogenesis. However, the subsets of vascular myeloid cells have eluded resolution due to shared marker expression and atypical heterogeneity in vascular tissues. We applied the high-dimensionality of mass cytometry to the study of myeloid cell subsets in atherosclerosis. Methods and Results: Apolipoprotein E-deficient (ApoE-/-) mice were fed a chow or a high fat (western) diet for 12 weeks...
May 2, 2018: Cardiovascular Research
https://www.readbyqxmd.com/read/29726551/high-coherence-plane-breaking-packaging-for-superconducting-qubits
#8
Nicholas T Bronn, Vivekananda P Adiga, Salvatore B Olivadese, Xian Wu, Jerry M Chow, David P Pappas
We demonstrate a pogo pin package for a superconducting quantum processor specifically designed with a nontrivial layout topology (e.g., a center qubit that cannot be accessed from the sides of the chip). Two experiments on two nominally identical superconducting quantum processors in pogo packages, which use commercially available parts and require modest machining tolerances, are performed at low temperature (10 mK) in a dilution refrigerator and both found to behave comparably to processors in standard planar packages with wirebonds where control and readout signals come in from the edges...
April 2018: Quantum science and technology
https://www.readbyqxmd.com/read/29725242/prospects-for-observing-and-localizing-gravitational-wave-transients-with-advanced-ligo-advanced-virgo-and-kagra
#9
REVIEW
B P Abbott, R Abbott, T D Abbott, M R Abernathy, F Acernese, K Ackley, C Adams, T Adams, P Addesso, R X Adhikari, V B Adya, C Affeldt, M Agathos, K Agatsuma, N Aggarwal, O D Aguiar, L Aiello, A Ain, P Ajith, T Akutsu, B Allen, A Allocca, P A Altin, A Ananyeva, S B Anderson, W G Anderson, M Ando, S Appert, K Arai, A Araya, M C Araya, J S Areeda, N Arnaud, K G Arun, H Asada, S Ascenzi, G Ashton, Y Aso, M Ast, S M Aston, P Astone, S Atsuta, P Aufmuth, C Aulbert, A Avila-Alvarez, K Awai, S Babak, P Bacon, M K M Bader, L Baiotti, P T Baker, F Baldaccini, G Ballardin, S W Ballmer, J C Barayoga, S E Barclay, B C Barish, D Barker, F Barone, B Barr, L Barsotti, M Barsuglia, D Barta, J Bartlett, M A Barton, I Bartos, R Bassiri, A Basti, J C Batch, C Baune, V Bavigadda, M Bazzan, B Bécsy, C Beer, M Bejger, I Belahcene, M Belgin, A S Bell, B K Berger, G Bergmann, C P L Berry, D Bersanetti, A Bertolini, J Betzwieser, S Bhagwat, R Bhandare, I A Bilenko, G Billingsley, C R Billman, J Birch, R Birney, O Birnholtz, S Biscans, A Bisht, M Bitossi, C Biwer, M A Bizouard, J K Blackburn, J Blackman, C D Blair, D G Blair, R M Blair, S Bloemen, O Bock, M Boer, G Bogaert, A Bohe, F Bondu, R Bonnand, B A Boom, R Bork, V Boschi, S Bose, Y Bouffanais, A Bozzi, C Bradaschia, P R Brady, V B Braginsky, M Branchesi, J E Brau, T Briant, A Brillet, M Brinkmann, V Brisson, P Brockill, J E Broida, A F Brooks, D A Brown, D D Brown, N M Brown, S Brunett, C C Buchanan, A Buikema, T Bulik, H J Bulten, A Buonanno, D Buskulic, C Buy, R L Byer, M Cabero, L Cadonati, G Cagnoli, C Cahillane, J Calderón Bustillo, T A Callister, E Calloni, J B Camp, K C Cannon, H Cao, J Cao, C D Capano, E Capocasa, F Carbognani, S Caride, J Casanueva Diaz, C Casentini, S Caudill, M Cavaglià, F Cavalier, R Cavalieri, G Cella, C B Cepeda, L Cerboni Baiardi, G Cerretani, E Cesarini, S J Chamberlin, M Chan, S Chao, P Charlton, E Chassande-Mottin, B D Cheeseboro, H Y Chen, Y Chen, H-P Cheng, A Chincarini, A Chiummo, T Chmiel, H S Cho, M Cho, J H Chow, N Christensen, Q Chu, A J K Chua, S Chua, S Chung, G Ciani, F Clara, J A Clark, F Cleva, C Cocchieri, E Coccia, P-F Cohadon, A Colla, C G Collette, L Cominsky, M Constancio, L Conti, S J Cooper, T R Corbitt, N Cornish, A Corsi, S Cortese, C A Costa, M W Coughlin, S B Coughlin, J-P Coulon, S T Countryman, P Couvares, P B Covas, E E Cowan, D M Coward, M J Cowart, D C Coyne, R Coyne, J D E Creighton, T D Creighton, J Cripe, S G Crowder, T J Cullen, A Cumming, L Cunningham, E Cuoco, T Dal Canton, S L Danilishin, S D'Antonio, K Danzmann, A Dasgupta, C F Da Silva Costa, V Dattilo, I Dave, M Davier, G S Davies, D Davis, E J Daw, B Day, R Day, S De, D DeBra, G Debreczeni, J Degallaix, M De Laurentis, S Deléglise, W Del Pozzo, T Denker, T Dent, V Dergachev, R De Rosa, R T DeRosa, R DeSalvo, R C Devine, S Dhurandhar, M C Díaz, L Di Fiore, M Di Giovanni, T Di Girolamo, A Di Lieto, S Di Pace, I Di Palma, A Di Virgilio, Z Doctor, K Doi, V Dolique, F Donovan, K L Dooley, S Doravari, I Dorrington, R Douglas, M Dovale Álvarez, T P Downes, M Drago, R W P Drever, J C Driggers, Z Du, M Ducrot, S E Dwyer, K Eda, T B Edo, M C Edwards, A Effler, H-B Eggenstein, P Ehrens, J Eichholz, S S Eikenberry, R A Eisenstein, R C Essick, Z Etienne, T Etzel, M Evans, T M Evans, R Everett, M Factourovich, V Fafone, H Fair, S Fairhurst, X Fan, S Farinon, B Farr, W M Farr, E J Fauchon-Jones, M Favata, M Fays, H Fehrmann, M M Fejer, A Fernández Galiana, I Ferrante, E C Ferreira, F Ferrini, F Fidecaro, I Fiori, D Fiorucci, R P Fisher, R Flaminio, M Fletcher, H Fong, S S Forsyth, J-D Fournier, S Frasca, F Frasconi, Z Frei, A Freise, R Frey, V Frey, E M Fries, P Fritschel, V V Frolov, Y Fujii, M-K Fujimoto, P Fulda, M Fyffe, H Gabbard, B U Gadre, S M Gaebel, J R Gair, L Gammaitoni, S G Gaonkar, F Garufi, G Gaur, V Gayathri, N Gehrels, G Gemme, E Genin, A Gennai, J George, L Gergely, V Germain, S Ghonge, Abhirup Ghosh, Archisman Ghosh, S Ghosh, J A Giaime, K D Giardina, A Giazotto, K Gill, A Glaefke, E Goetz, R Goetz, L Gondan, G González, J M Gonzalez Castro, A Gopakumar, M L Gorodetsky, S E Gossan, M Gosselin, R Gouaty, A Grado, C Graef, M Granata, A Grant, S Gras, C Gray, G Greco, A C Green, P Groot, H Grote, S Grunewald, G M Guidi, X Guo, A Gupta, M K Gupta, K E Gushwa, E K Gustafson, R Gustafson, J J Hacker, A Hagiwara, B R Hall, E D Hall, G Hammond, M Haney, M M Hanke, J Hanks, C Hanna, M D Hannam, J Hanson, T Hardwick, J Harms, G M Harry, I W Harry, M J Hart, M T Hartman, C-J Haster, K Haughian, K Hayama, J Healy, A Heidmann, M C Heintze, H Heitmann, P Hello, G Hemming, M Hendry, I S Heng, J Hennig, J Henry, A W Heptonstall, M Heurs, S Hild, E Hirose, D Hoak, D Hofman, K Holt, D E Holz, P Hopkins, J Hough, E A Houston, E J Howell, Y M Hu, E A Huerta, D Huet, B Hughey, S Husa, S H Huttner, T Huynh-Dinh, N Indik, D R Ingram, R Inta, K Ioka, H N Isa, J-M Isac, M Isi, T Isogai, Y Itoh, B R Iyer, K Izumi, T Jacqmin, K Jani, P Jaranowski, S Jawahar, F Jiménez-Forteza, W W Johnson, D I Jones, R Jones, R J G Jonker, L Ju, J Junker, T Kagawa, T Kajita, M Kakizaki, C V Kalaghatgi, V Kalogera, M Kamiizumi, N Kanda, S Kandhasamy, S Kanemura, M Kaneyama, G Kang, J B Kanner, S Karki, K S Karvinen, M Kasprzack, Y Kataoka, E Katsavounidis, W Katzman, S Kaufer, T Kaur, K Kawabe, N Kawai, S Kawamura, F Kéfélian, D Keitel, D B Kelley, R Kennedy, J S Key, F Y Khalili, I Khan, S Khan, Z Khan, E A Khazanov, N Kijbunchoo, C Kim, H Kim, J C Kim, J Kim, W Kim, Y-M Kim, S J Kimbrell, N Kimura, E J King, P J King, R Kirchhoff, J S Kissel, B Klein, L Kleybolte, S Klimenko, P Koch, S M Koehlenbeck, Y Kojima, K Kokeyama, S Koley, K Komori, V Kondrashov, A Kontos, M Korobko, W Z Korth, K Kotake, I Kowalska, D B Kozak, C Krämer, V Kringel, B Krishnan, A Królak, G Kuehn, P Kumar, Rahul Kumar, Rakesh Kumar, L Kuo, K Kuroda, A Kutynia, Y Kuwahara, B D Lackey, M Landry, R N Lang, J Lange, B Lantz, R K Lanza, A Lartaux-Vollard, P D Lasky, M Laxen, A Lazzarini, C Lazzaro, P Leaci, S Leavey, E O Lebigot, C H Lee, H K Lee, H M Lee, H W Lee, K Lee, J Lehmann, A Lenon, M Leonardi, J R Leong, N Leroy, N Letendre, Y Levin, T G F Li, A Libson, T B Littenberg, J Liu, N A Lockerbie, A L Lombardi, L T London, J E Lord, M Lorenzini, V Loriette, M Lormand, G Losurdo, J D Lough, C O Lousto, G Lovelace, H Lück, A P Lundgren, R Lynch, Y Ma, S Macfoy, B Machenschalk, M MacInnis, D M Macleod, F Magaña-Sandoval, E Majorana, I Maksimovic, V Malvezzi, N Man, V Mandic, V Mangano, S Mano, G L Mansell, M Manske, M Mantovani, F Marchesoni, M Marchio, F Marion, S Márka, Z Márka, A S Markosyan, E Maros, F Martelli, L Martellini, I W Martin, D V Martynov, K Mason, A Masserot, T J Massinger, M Masso-Reid, S Mastrogiovanni, F Matichard, L Matone, N Matsumoto, F Matsushima, N Mavalvala, N Mazumder, R McCarthy, D E McClelland, S McCormick, C McGrath, S C McGuire, G McIntyre, J McIver, D J McManus, T McRae, S T McWilliams, D Meacher, G D Meadors, J Meidam, A Melatos, G Mendell, D Mendoza-Gandara, R A Mercer, E L Merilh, M Merzougui, S Meshkov, C Messenger, C Messick, R Metzdorff, P M Meyers, F Mezzani, H Miao, C Michel, Y Michimura, H Middleton, E E Mikhailov, L Milano, A L Miller, A Miller, B B Miller, J Miller, M Millhouse, Y Minenkov, J Ming, S Mirshekari, C Mishra, V P Mitrofanov, G Mitselmakher, R Mittleman, O Miyakawa, A Miyamoto, T Miyamoto, S Miyoki, A Moggi, M Mohan, S R P Mohapatra, M Montani, B C Moore, C J Moore, D Moraru, G Moreno, W Morii, S Morisaki, Y Moriwaki, S R Morriss, B Mours, C M Mow-Lowry, G Mueller, A W Muir, Arunava Mukherjee, D Mukherjee, S Mukherjee, N Mukund, A Mullavey, J Munch, E A M Muniz, P G Murray, A Mytidis, S Nagano, K Nakamura, T Nakamura, H Nakano, Masaya Nakano, Masayuki Nakano, K Nakao, K Napier, I Nardecchia, T Narikawa, L Naticchioni, G Nelemans, T J N Nelson, M Neri, M Nery, A Neunzert, J M Newport, G Newton, T T Nguyen, W-T Ni, A B Nielsen, S Nissanke, A Nitz, A Noack, F Nocera, D Nolting, M E N Normandin, L K Nuttall, J Oberling, E Ochsner, E Oelker, G H Ogin, J J Oh, S H Oh, M Ohashi, N Ohishi, M Ohkawa, F Ohme, K Okutomi, M Oliver, K Ono, Y Ono, K Oohara, P Oppermann, Richard J Oram, B O'Reilly, R O'Shaughnessy, D J Ottaway, H Overmier, B J Owen, A E Pace, J Page, A Pai, S A Pai, J R Palamos, O Palashov, C Palomba, A Pal-Singh, H Pan, C Pankow, F Pannarale, B C Pant, F Paoletti, A Paoli, M A Papa, H R Paris, W Parker, D Pascucci, A Pasqualetti, R Passaquieti, D Passuello, B Patricelli, B L Pearlstone, M Pedraza, R Pedurand, L Pekowsky, A Pele, F E Peña Arellano, S Penn, C J Perez, A Perreca, L M Perri, H P Pfeiffer, M Phelps, O J Piccinni, M Pichot, F Piergiovanni, V Pierro, G Pillant, L Pinard, I M Pinto, M Pitkin, M Poe, R Poggiani, P Popolizio, A Post, J Powell, J Prasad, J W W Pratt, V Predoi, T Prestegard, M Prijatelj, M Principe, S Privitera, G A Prodi, L G Prokhorov, O Puncken, M Punturo, P Puppo, M Pürrer, H Qi, J Qin, S Qiu, V Quetschke, E A Quintero, R Quitzow-James, F J Raab, D S Rabeling, H Radkins, P Raffai, S Raja, C Rajan, M Rakhmanov, P Rapagnani, V Raymond, M Razzano, V Re, J Read, T Regimbau, L Rei, S Reid, D H Reitze, H Rew, S D Reyes, E Rhoades, F Ricci, K Riles, M Rizzo, N A Robertson, R Robie, F Robinet, A Rocchi, L Rolland, J G Rollins, V J Roma, R Romano, J H Romie, D Rosińska, S Rowan, A Rüdiger, P Ruggi, K Ryan, S Sachdev, T Sadecki, L Sadeghian, N Sago, M Saijo, Y Saito, K Sakai, M Sakellariadou, L Salconi, M Saleem, F Salemi, A Samajdar, L Sammut, L M Sampson, E J Sanchez, V Sandberg, J R Sanders, Y Sasaki, B Sassolas, B S Sathyaprakash, S Sato, T Sato, P R Saulson, O Sauter, R L Savage, A Sawadsky, P Schale, J Scheuer, E Schmidt, J Schmidt, P Schmidt, R Schnabel, R M S Schofield, A Schönbeck, E Schreiber, D Schuette, B F Schutz, S G Schwalbe, J Scott, S M Scott, T Sekiguchi, Y Sekiguchi, D Sellers, A S Sengupta, D Sentenac, V Sequino, A Sergeev, Y Setyawati, D A Shaddock, T J Shaffer, M S Shahriar, B Shapiro, P Shawhan, A Sheperd, M Shibata, Y Shikano, T Shimoda, A Shoda, D H Shoemaker, D M Shoemaker, K Siellez, X Siemens, M Sieniawska, D Sigg, A D Silva, A Singer, L P Singer, A Singh, R Singh, A Singhal, A M Sintes, B J J Slagmolen, B Smith, J R Smith, R J E Smith, K Somiya, E J Son, B Sorazu, F Sorrentino, T Souradeep, A P Spencer, A K Srivastava, A Staley, M Steinke, J Steinlechner, S Steinlechner, D Steinmeyer, B C Stephens, S P Stevenson, R Stone, K A Strain, N Straniero, G Stratta, S E Strigin, R Sturani, A L Stuver, Y Sugimoto, T Z Summerscales, L Sun, S Sunil, P J Sutton, T Suzuki, B L Swinkels, M J Szczepańczyk, M Tacca, H Tagoshi, S Takada, H Takahashi, R Takahashi, A Takamori, D Talukder, H Tanaka, K Tanaka, T Tanaka, D B Tanner, M Tápai, A Taracchini, D Tatsumi, R Taylor, S Telada, T Theeg, E G Thomas, M Thomas, P Thomas, K A Thorne, E Thrane, T Tippens, S Tiwari, V Tiwari, K V Tokmakov, K Toland, T Tomaru, C Tomlinson, M Tonelli, Z Tornasi, C I Torrie, D Töyrä, F Travasso, G Traylor, D Trifirò, J Trinastic, M C Tringali, L Trozzo, M Tse, R Tso, K Tsubono, T Tsuzuki, M Turconi, D Tuyenbayev, T Uchiyama, T Uehara, S Ueki, K Ueno, D Ugolini, C S Unnikrishnan, A L Urban, T Ushiba, S A Usman, H Vahlbruch, G Vajente, G Valdes, N van Bakel, M van Beuzekom, J F J van den Brand, C Van Den Broeck, D C Vander-Hyde, L van der Schaaf, J V van Heijningen, M H P M van Putten, A A van Veggel, M Vardaro, V Varma, S Vass, M Vasúth, A Vecchio, G Vedovato, J Veitch, P J Veitch, K Venkateswara, G Venugopalan, D Verkindt, F Vetrano, A Viceré, A D Viets, S Vinciguerra, D J Vine, J-Y Vinet, S Vitale, T Vo, H Vocca, C Vorvick, D V Voss, W D Vousden, S P Vyatchanin, A R Wade, L E Wade, M Wade, T Wakamatsu, M Walker, L Wallace, S Walsh, G Wang, H Wang, M Wang, Y Wang, R L Ward, J Warner, M Was, J Watchi, B Weaver, L-W Wei, M Weinert, A J Weinstein, R Weiss, L Wen, P Weßels, T Westphal, K Wette, J T Whelan, B F Whiting, C Whittle, D Williams, R D Williams, A R Williamson, J L Willis, B Willke, M H Wimmer, W Winkler, C C Wipf, H Wittel, G Woan, J Woehler, J Worden, J L Wright, D S Wu, G Wu, W Yam, H Yamamoto, K Yamamoto, T Yamamoto, C C Yancey, K Yano, M J Yap, J Yokoyama, T Yokozawa, T H Yoon, Hang Yu, Haocun Yu, H Yuzurihara, M Yvert, A Zadrożny, L Zangrando, M Zanolin, S Zeidler, J-P Zendri, M Zevin, L Zhang, M Zhang, T Zhang, Y Zhang, C Zhao, M Zhou, Z Zhou, S J Zhu, X J Zhu, M E Zucker, J Zweizig
We present possible observing scenarios for the Advanced LIGO, Advanced Virgo and KAGRA gravitational-wave detectors over the next decade, with the intention of providing information to the astronomy community to facilitate planning for multi-messenger astronomy with gravitational waves. We estimate the sensitivity of the network to transient gravitational-wave signals, and study the capability of the network to determine the sky location of the source. We report our findings for gravitational-wave transients, with particular focus on gravitational-wave signals from the inspiral of binary neutron star systems, which are the most promising targets for multi-messenger astronomy...
2018: Living Reviews in Relativity
https://www.readbyqxmd.com/read/29710855/myoprotective-potential-of-creatine-is-greater-than-whey-protein-after-chemically-induced-damage-in-rat-skeletal-muscle
#10
Matthew B Cooke, Emma Rybalka, Christos G Stathis, Alan Hayes
The myoprotective effects of creatine monohydrate (CR) and whey protein (WP) are equivocal, with the use of proxy measures of muscle damage making interpretation of their effectiveness limited. The purpose of the study was to determine the effects of CR and WP supplementation on muscle damage and recovery following controlled, chemically-induced muscle damage. Degeneration of the extensor digitorum longus (EDL) muscle was induced by bupivacaine in rats supplemented with either CR, WP, or standard rat chow (CON)...
April 30, 2018: Nutrients
https://www.readbyqxmd.com/read/29710329/chronic-meningitis-investigated-via-metagenomic-next-generation-sequencing
#11
Michael R Wilson, Brian D O'Donovan, Jeffrey M Gelfand, Hannah A Sample, Felicia C Chow, John P Betjemann, Maulik P Shah, Megan B Richie, Mark P Gorman, Rula A Hajj-Ali, Leonard H Calabrese, Kelsey C Zorn, Eric D Chow, John E Greenlee, Jonathan H Blum, Gary Green, Lillian M Khan, Debarko Banerji, Charles Langelier, Chloe Bryson-Cahn, Whitney Harrington, Jairam R Lingappa, Niraj M Shanbhag, Ari J Green, Bruce J Brew, Ariane Soldatos, Luke Strnad, Sarah B Doernberg, Cheryl A Jay, Vanja Douglas, S Andrew Josephson, Joseph L DeRisi
Importance: Identifying infectious causes of subacute or chronic meningitis can be challenging. Enhanced, unbiased diagnostic approaches are needed. Objective: To present a case series of patients with diagnostically challenging subacute or chronic meningitis using metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF) supported by a statistical framework generated from mNGS of control samples from the environment and from patients who were noninfectious...
April 16, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29710216/association-of-dasatinib-with-progression-free-survival-among-patients-with-advanced-gastrointestinal-stromal-tumors-resistant-to-imatinib
#12
Scott M Schuetze, Vanessa Bolejack, Dafydd G Thomas, Margaret von Mehren, Shreyaskumar Patel, Brian Samuels, Edwin Choy, Gina D'Amato, Arthur P Staddon, Kristen N Ganjoo, Warren A Chow, Daniel A Rushing, Charles A Forscher, Dennis A Priebat, David M Loeb, Rashmi Chugh, Scott Okuno, Denise K Reinke, Laurence H Baker
Importance: Gastrointestinal stromal tumors (GISTs) are life-threatening when metastatic or not amenable to surgical removal. In a few patients with advanced GISTs refractory to imatinib mesylate, treatment with sunitinib malate followed by regorafenib provides tumor control; however, additional active treatments are needed for most patients. Objective: To evaluate the 6-month progression-free survival (PFS), tumor objective response, and overall survival rates in patients with GISTs treated with dasatinib...
April 26, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29708596/knock-out-of-the-gsta4-gene-in-male-mice-leads-to-an-altered-pattern-of-hepatic-protein-carbonylation-and-enhanced-inflammation-following-chronic-consumption-of-an-ethanol-diet
#13
Colin T Shearn, Casey F Pulliam, Kim Pedersen, Kyle Meredith, Kelly E Mercer, Laura M Saba, David J Orlicky, Martin J Ronis, Dennis R Petersen
BACKGROUND: Glutathione-S-transferase A4-4 (GSTA4) is a key enzyme for removal of toxic lipid peroxidation products such as 4-hydroxynonenal (4-HNE). In the current study, we examined the potential role of GSTA4 on protein carbonylation and progression of alcoholic liver disease (ALD) by examining the development of liver injury in male wild type SV/J mice (WT) and SV/J mice lacking functional GSTA4 (GSTA4-/- mice). METHODS: Adult male WT and GSTA4-/- mice were fed chow (N = 10-12) or high fat Lieber-DeCarli liquid diets containing up to 28% calories as ethanol (EtOH) (N = 18-20) for 116 days...
April 30, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29704172/a-direct-oral-factor-xa-inhibitor-edoxaban-ameliorates-neointimal-hyperplasia-following-vascular-injury-and-thrombosis-in-apolipoprotein-e-deficient-mice
#14
Yoshiyuki Morishima, Yuko Honda
Vascular injury activates the coagulation cascade. Some studies report that coagulation factor Xa and thrombin are implicated in proliferation of vascular smooth muscle cells and neointimal hyperplasia after vascular injury. The aim of this study was to determine the effect of an oral direct factor Xa inhibitor, edoxaban, on neointimal hyperplasia following the carotid artery injury in apolipoprotein E (ApoE)-deficient mice. Vascular injury was induced by the application of 10% ferric chloride to the carotid artery for 3 min in ApoE-deficient mice...
April 27, 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29689132/alcohol-delays-the-onset-of-puberty-in-the-female-rat-by-altering-key-hypothalamic-events
#15
Vinod K Srivastava, Jill K Hiney, William L Dees
BACKGROUND: Because alcohol (ALC) delays signs of pubertal development, we assessed the time course of events associated with the synthesis of critical hypothalamic peptides that regulate secretion of luteinizing hormone-releasing hormone (LHRH), the peptide that drives the pubertal process. METHODS: Immature female rats were administered either lab chow or Bio-Serve isocaloric control or ALC liquid diets from 27 through 33 days of age. On days 28, 29, 31 and 33 animals were killed by decapitation and tissue blocks containing the medial basal hypothalamus (MBH) and the rostral hypothalamic area (RHA) were isolated and stored frozen until assessed by Western blot analysis...
April 24, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29686722/energy-restriction-exercise-and-atorvastatin-treatment-improve-endothelial-dysfunction-and-inhibit-mirna-155-in-the-erectile-tissue-of-the-aged-rat
#16
B Rocha, A R Rodrigues, I Tomada, M J Martins, J T Guimarães, A M Gouveia, H Almeida, D Neves
Background: Endothelial dysfunction underlies cardiovascular disease that frequently affects aged individuals. Characterized by local decrease in nitric oxide, it results from down-regulation of endothelial nitric oxide synthase (eNOS) expression/activity. Aiming to elucidate the molecular mechanisms involved in age-related endothelial dysfunction and to unveil potential therapeutic targets, we tested how diet pattern, exercise and atorvastatin modulate the expression of eNOS, inducible NOS (iNOS), endothelin-1, sirtuins (SIRT) and microRNA-155 in the erectile tissue of high-fat fed aged rats...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29669181/racial-disparity-in-oncologic-and-quality-of-life-outcomes-in-patients-with-locally-advanced-head-and-neck-squamous-cell-carcinomas-enrolled-in-a-randomized-phase-2-trial
#17
Margaret K Guerriero, Mary W Redman, Kelsey K Baker, Renato G Martins, Keith Eaton, Laura Q Chow, Rafael Santana-Davila, Christina Baik, Bernardo H Goulart, Sylvia Lee, Cristina P Rodriguez
BACKGROUND: To better understand patient-reported quality of life (PRQOL) for patients with head and neck cancer, PRQOL scores were collected in a clinical trial. METHODS: Patients were randomized to arm A (70 Gy of radiation with cisplatin) or arm B (70 Gy of radiation with cisplatin plus erlotinib at 150 mg daily). PRQOL scores were measured on days -7 (arm B only), 0, 30, and 180 with the University of Washington Quality of Life Questionnaire. Associations with clinical factors and outcomes were explored with linear mixed, logistic, and Cox regression models...
April 18, 2018: Cancer
https://www.readbyqxmd.com/read/29662761/inflammation-and-age-associated-skeletal-muscle-deterioration-sarcopaenia
#18
REVIEW
Jinyu Wang, Kwok-Sui Leung, Simon Kwoon-Ho Chow, Wing-Hoi Cheung
Ageing is accompanied by chronic inflammatory responses due to elevated circulatory inflammatory cytokine production. Several inflammatory cytokines have been shown to be responsible for a decrease in muscle mass. However, little is known about the possible relationship between inflammation and sarcopaenia. This review aims to summarise the existing evidence about inflammation and sarcopaenia. Sarcopaenia is defined as an age-related decrease of muscle mass and/or muscle strength; it is caused by multiple factors, such as skeletal muscle atrophy, neuromuscular junction degeneration, hormone imbalance, cytokine imbalance, protein synthesis and proteolysis...
July 2017: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29651739/prognostic-utility-of-splenic-response-ratio-in-dipyridamole-pet-myocardial-perfusion-imaging
#19
Karan Bami, Shrankhala Tewari, Fadi Guirguis, Linda Garrard, Ann Guo, Alomgir Hossain, Terrence D Ruddy, Rob S B Beanlands, Robert A deKemp, Benjamin J W Chow, Girish Dwivedi
BACKGROUND: Cardiac magnetic resonance perfusion studies with adenosine stress have shown that splenic response can identify patients with inadequate pharmacologic stress. We investigate the incremental prognostic impact of splenic response ratio (SRR) in patients with normal Rubidium (Rb)-82 PET myocardial perfusion imaging (MPI). METHODS: Consecutive patients undergoing dipyridamole Rb-82 PET MPI for the evaluation of coronary artery disease were screened. Spleen and liver Rb-82 activity was measured and the SRR was calculated: SRR = (Spleen stress/Liver stress)/(Spleen rest/Liver rest)...
April 12, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29648997/interactive-effects-of-alcohol-and-chloroquine-on-hematologic-profile-of-wistar-rats
#20
Dimkpa Uchechukwu, Kelechi Loveth Ezeudensi, Babatunde Ishola Adejumo, Chinwe Obianuju Ewenighi, Elizabeth Enohnyaket Besong, Grace Ottah Umahi, Albert Nkereuwem Eteudo, Bright Uneze
BACKGROUND: There is paucity of information on the adverse effects of alcohol - chloroquine interaction on hematological parameters. To investigate the effects of concurrent administration of chloroquine and ethanol on hematologic parameters of adult Wistar rats and the ameliorative role of vitamin B12 and folic acid supplementation on any adverse effects. METHODS: Some 30 adult Wistar rats weighing 120-200 g were assigned to six major groups of five rats each according to their weights...
April 12, 2018: Journal of Basic and Clinical Physiology and Pharmacology
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