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eczema young adults

J F Hayes, G M Khandaker, J Anderson, D Mackay, S Zammit, G Lewis, D J Smith, D P J Osborn
BACKGROUND: There are no existing longitudinal studies of inflammatory markers and atopic disorders in childhood and risk of hypomanic symptoms in adulthood. This study examined if childhood: (1) serum interleukin-6 (IL-6) and C-reactive protein (CRP); and (2) asthma and/or eczema are associated with features of hypomania in young adulthood. METHOD: Participants in the Avon Longitudinal Study of Parents and Children, a prospective general population UK birth cohort, had non-fasting blood samples for IL-6 and CRP measurement at the age of 9 years (n = 4645), and parents answered a question about doctor-diagnosed atopic illness before the age of 10 years (n = 7809)...
August 1, 2016: Psychological Medicine
Samantha Glass, Anh Phan, Jessica N Williams, Christopher R Flowers, Jean L Koff
Non-Hodgkin lymphomas include a biologically and clinically heterogeneous group of cancers distinguished by genetics, histology, and treatment outcomes. New discoveries regarding the genomic alterations and epidemiological exposures associated with these lymphomas have enhanced our understanding of factors that contribute to lymphomagenesis for specific subtypes. We explore the impact of normal B-cell biology engineered for recognizing a wide variety of antigens on the development of specific lymphoma subtypes, review lymphoma genetics, and examine the epidemiology of B-cell NHLs including recent investigations of risk factors for particular lymphoma subtypes based on large pooled analyses...
March 2016: Discovery Medicine
Eva Rönmark, Helena Backman, Linnea Hedman
Allergic sensitization, an important risk factor for allergic diseases such as asthma and rhinitis, has increased worldwide. Almost half of the young adult population is sensitized to common airborne allergens. Parallel, the prevalence of asthma and clinical allergy also increased all over the world. Allergic diseases are the most common diseases among children, adolescents and young adults in Sweden. Among adults, 8-10% have asthma, 30% rhinitis and 11% eczema. Among children and adolescents around 5-8% report food allergy...
2016: Läkartidningen
Stephan Miehlke
Eosinophilic esophagitis (EoE) may affect humans at any age with a predominance for Caucasian males. The clinical manifestation of EoE varies depending on the patient's age. Infants and young children may primarily present with unspecific symptoms such as feeding problems, vomiting and abdominal pain. In adolescents and adults, dysphagia and food impactation become the predominant symptoms. EoE should also be considered in cases of refractory heartburn in both children and adults. Concomitant allergic diseases such as asthma, rhinitis and eczema, as well as peripheral eosinophilia and elevated total serum IgE values are common in pediatric and adult EoE patients...
October 2015: Best Practice & Research. Clinical Gastroenterology
S A Alduraywish, C J Lodge, B Campbell, K J Allen, B Erbas, A J Lowe, S C Dharmage
BACKGROUND: There is growing evidence for an increase in food allergies. The question of whether early life food sensitization, a primary step in food allergies, leads to other allergic disease is a controversial but important issue. Birth cohorts are an ideal design to answer this question. OBJECTIVES: We aimed to systematically investigate and meta-analyse the evidence for associations between early food sensitization and allergic disease in birth cohorts. METHODS: MEDLINE and SCOPUS databases were searched for birth cohorts that have investigated the association between food sensitization in the first 2 years and subsequent wheeze/asthma, eczema and/or allergic rhinitis...
January 2016: Allergy
Anthony A Cochet, Allyson E Cochet, James M Francis
BACKGROUND: Eosinophilic esophagitis (EoE) is an emerging esophageal disease associated with dysphagia and food impaction. Practice guidelines have only recently been developed. It affects 1/1000 individuals, predominantly young men. As this demographic represents a substantial portion of the military aviation population, aerospace medicine clinicians should be familiar with this diagnosis when evaluating dysphagia or impactions. CASE REPORT: A 23-yr-old Caucasian man, a U...
August 2015: Aerospace Medicine and Human Performance
Ting Zhao, Wa-li Liu, Ping Wu, Yong-jun Liu, Yu-he Yan, Jing Wang, Chi-jin Zhang, Guang-rui Li, Gang Li, Fu-sheng Wang, Min Fan
The clinical study was conducted to further evaluation the effectiveness and safety of Fangfeng Tongsheng granule in the treatment of sub-acute eczema (superficial cold and interior heat syndrome, exterior and interior sthenic syndrome). In the block randomized, multi-centered study, totally 108 patients were enrolled and assigned to two groups: 72 patients in the test group and 36 patients in the placebo control group. Those in the test group took Fangfeng Tongsheng granule with the dose of 3 g, twice a day, while those in the control group were give simulated agent granules with the same dose...
April 2015: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Maximilian Blanter, Jennifer Vickers, Marian Russo, Bijan Safai
Eczema herpeticum is an easily missed entity most commonly seen in the pediatric population and carries the risk of systemic compromise and a 10% mortality rate. Clinicians should maintain high clinical suspicion when encountering children or young adults with a history of atopic dermatitis or other erosive dermatoses and who present with vesicular lesions, punched-out erosions, and systemic symptoms. We present 3 severe cases of eczema herpeticum that were potentially overlooked and demonstrate the need for elevated awareness to avoid potential pitfalls...
August 2015: Pediatric Emergency Care
Junxiang Wei, Jessica Gerlich, Christian Vogelberg, Erika von Mutius, Doris Windstetter, Jon Genuneit, Gudrun Weinmayr, Dennis Nowak, Katja Radon
PURPOSE: Patients with atopic dermatitis (AD) are at high risk of chronic hand eczema. In this prospective cohort study, we assessed the influence of pre-hire-onset AD on the first job choice. We also analysed the potential association between AD and usage of preventive measures in high-risk occupations. METHODS: Subjects (aged 19-24 years) who were followed from childhood until the second Study on Occupational Allergy Risks and indicated a job were included (n = 1566)...
April 2016: International Archives of Occupational and Environmental Health
Sandra Lawton, Margaret Cox, Julie Van Onselen
No abstract text is available yet for this article.
May 2015: Journal of Family Health
Julie Van Onselen
No abstract text is available yet for this article.
May 2015: Journal of Family Health
Si-Heon Kim, Jae Hur, Jae-Yeon Jang, Hae-Sim Park, Chang Hyung Hong, Sang Joon Son, Ki Jung Chang
The relationship between atopic dermatitis (AD) and psychological distress has been well established for children and adolescents. However, it is unclear whether this relationship exists in young adults. This study aimed to assess the relationship between AD and psychological distress in young male adults in South Korea. A cross-sectional study was conducted using regional conscription data from 2008 to 2012. A dermatologist diagnosed AD based on historical and clinical features, and determined severity using the eczema area and severity index...
June 2015: Medicine (Baltimore)
Thomas Werfel, Annice Heratizadeh, Margarete Niebuhr, Alexander Kapp, Lennart Matthias Roesner, Annika Karch, Veit J Erpenbeck, Christian Lösche, Thomas Jung, Norbert Krug, Philipp Badorrek, Jens M Hohlfeld
BACKGROUND: It has frequently been speculated that pruritus and skin lesions develop after topical exposure to aeroallergens in sensitized patients with atopic dermatitis (AD). OBJECTIVE: We sought to study cutaneous reactions to grass pollen in adult patients with AD with accompanying clear IgE sensitization to grass allergen in an environmental challenge chamber using a monocenter, double-blind, placebo-controlled study design. METHODS: Subjects were challenged on 2 consecutive days with either 4000 pollen grains/m(3) of Dactylis glomerata pollen or clean air...
July 2015: Journal of Allergy and Clinical Immunology
Renata C Scalco, Vivian Hwa, Horacio M Domené, Héctor G Jasper, Alicia Belgorosky, Roxana Marino, Alberto M Pereira, Carlos A Tonelli, Jan M Wit, Ron G Rosenfeld, Alexander A L Jorge
CONTEXT AND OBJECTIVE: GH insensitivity with immune dysfunction caused by STAT5B mutations is an autosomal recessive condition. Heterozygous mutations in other genes involved in growth regulation were previously associated with a mild height reduction. Our objective was to assess for the first time the phenotype of heterozygous STAT5B mutations. METHODS: We genotyped and performed clinical and laboratory evaluations in 52 relatives of two previously described Brazilian brothers with homozygous STAT5B c...
September 2015: European Journal of Endocrinology
Irena Ivković-Jureković
Oral allergy syndrome (OAS) is an IgE antibody-mediated allergic reaction that occurs after consumption of fresh fruits and veg etables in patients with allergy to pollen. Symptoms arise due to cross-reactivity between pollen and plant-derived food and another term used for this syndrome is pollen-food allergy syndrome. The patient is sensitized with pollen and exhibits an allergic reaction to food antigen with structural similarity to the pollen. OAS is rarely seen in young children, but the prevalence increases with age and OAS is the most common manifestation of food allergy in adolescents and adults...
June 2014: Acta Medica Croatica: C̆asopis Hravatske Akademije Medicinskih Znanosti
B C Martel, L Blom, B Dyring-Andersen, L Skov, K Thestrup-Pedersen, S Skov, K Skak, L K Poulsen
In atopic dermatitis (AD), the inflammatory response between skin-infiltrating T cells and keratinocytes is fundamental to the development of chronic lesional eczema. The aim of this study was to investigate whether skin-derived T cells from AD patients could induce an inflammatory response in mice through keratinocyte activation and consequently cause the development of eczematous lesions. Punch biopsies of the lesional skin from AD patients were used to establish skin-derived T cell cultures, which were transferred to NOD...
August 2015: Scandinavian Journal of Immunology
Niti Khunger, Anupama Molpariya, Arjun Khunger
Tattooing is a process of implantation of permanent pigment granules in the skin. Tattoos can be decorative, medical or accidental. There has been a exponential increase in decorative tattooing as a body art in teenagers and young adults. Unfortunately there are no legislations to promote safe tattooing, hence complications are quite common. Superficial and deep local infections, systemic infections, allergic reactions, photodermatitis, granulomatous reactions and lichenoid reactions may occur. Skin diseases localised on the tattooed area, such as eczema, psoriasis, lichen planus, and morphea can be occasionally seen...
January 2015: Journal of Cutaneous and Aesthetic Surgery
S Bhattarai, S Agrawal, A Rijal
Hand eczema (HE) is a common and distressing condition that is perplexing to the patient and the physician alike. To study the frequency and clinical features of hand eczema and to correlate the frequency of atopy and contact sensitization with different clinical features a total of 61 clinically diagnosed patient of Hand eczema were included within a period of one year. Patch test was done in 47 patients and graded accordingly. The frequency of hand eczema was 0.57%. Morphologically pompholyx was the most common type while aetiologically endogenous hand eczema was the commonest...
September 2014: Nepal Medical College Journal: NMCJ
Jonathan I Silverberg
IMPORTANCE: Little is known about the health burden of adult eczema in the United States. OBJECTIVE: To study the out-of-pocket costs, health care access and utilization in adult eczema in the United States. DESIGN, SETTING, AND PARTICIPANTS: Two US population-based studies, the 2010 and 2012 National Health Interview Surveys, surveyed 27 157 and 34 613 adults (ages 18-85 years). EXPOSURES: History of eczema. MAIN OUTCOMES AND MEASURES: The out-of-pocket costs, lost workdays, days in bed, and access to care...
July 2015: JAMA Dermatology
Yoshihiro Miyake, Shinichi Hitsumoto, Keiko Tanaka, Masashi Arakawa
We examined the association between thymic stromal lymphopoietin (TSLP) single nucleotide polymorphisms (SNPs) and eczema in young adult Japanese women. Cases were 188 women who met the criteria of the International Study of Asthma and Allergies in Childhood (ISAAC) for eczema. Controls were 565 women without eczema according to the ISAAC criteria, who had not been diagnosed with asthma, atopic eczema, and/or allergic rhinitis by a doctor and who had no asthma as defined by the European Community Respiratory Health Survey criteria and no rhinoconjunctivitis according to the ISAAC criteria...
August 2015: Inflammation
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