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https://www.readbyqxmd.com/read/28577553/the-refractive-state-of-the-eye-in-icelandic-horses-with-the-silver-mutation
#1
Maria K Johansson, Kim Jäderkvist Fegraeus, Gabriella Lindgren, Björn Ekesten
BACKGROUND: The syndrome Multiple Congenital Ocular Anomalies (MCOA) is a congenital eye disorder in horses. Both the MCOA syndrome and the Silver coat colour in horses are caused by the same missense mutation in the premelanosome protein (PMEL) gene. Horses homozygous for the Silver mutation (TT) are affected by multiple ocular defects causing visual impairment or blindness. Horses heterozygous for the Silver mutation (CT) have less severe clinical signs, usually cysts arising from the ciliary body iris or retina temporally...
June 2, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28541267/choroidal-melanoma-sector-melanocytosis-and-retinal-pigment-epithelial-microdetachments-in-birt-hogg-dub%C3%A3-syndrome
#2
Charlotte L Marous, Molly R Marous, R Joel Welch, Jerry A Shields, Carol L Shields
PURPOSE: Birt-Hogg-Dubé Syndrome (BHDS) is a rare autosomal dominant condition that can predispose patients to numerous cutaneous fibrofolliculomas and other cutaneous lesions, pulmonary cysts with spontaneous pneumothorax, and multifocal renal tumors and cancer. The genetic mutations responsible for BHDS are related to tumor suppression and the mammalian target of rapamycin (mTOR) pathway. Previous reports of the ocular findings in BHDS include eyelid fibrofolliculomas, "flecked chorioretinopathy," and one report of choroidal melanoma...
May 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28528833/bilobed-iris-stromal-epithelial-cyst
#3
Vasilios P Papastefanou, Victoria M L Cohen
No abstract text is available yet for this article.
June 2017: Ophthalmology
https://www.readbyqxmd.com/read/28470658/-free-floating-intraocular-cysts
#4
Jens Ulrich Werner, Gerhard K Lang, Christian Enders
Background Free-floating intraocular cysts may be found in the anterior chamber (FZV) and the vitreous (FZG). The first description of a cyst was 150 years ago, and they are considered to be ocular rarities. Materials and Methods The actual knowledge about FZV and FZG is shown on the basis of two exemplary patients. Results and Discussion Patient 1 had a FZV as an incidental finding which had a smooth surface, a slight pigmentation and was translucent. The ultrasound biomicroscopy revealed an echo-free interior space...
May 3, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28399346/tumors-and-related-lesions-of-the-pigmented-epithelium
#5
Jerry A Shields, Carol L Shields
Several tumors and pseudotumors can arise from the iris pigment epithelium (IPE), ciliary pigment epithelium (CPE), and retinal pigment epithelium (RPE), including cysts of the IPE, solitary congenital hypertrophy of the RPE (CHRPE), multifocal CHRPE ("bear tracks"), congenital simple hamartoma of the RPE, combined hamartoma of the retina and RPE, and acquired epithelioma of IPE, CPE, and RPE. This article describes examples of pigment epithelial tumors and pseudotumors by reviewing the literature and cases on file in the Oncology Service at Wills Eye Hospital...
March 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28356777/intraocular-eyelashes-and-iris-cyst-in-anterior-chamber-following-penetrating-eye-injury-a-case-report
#6
Sabin Sahu, Lila Raj Puri, Sanjay Kumar Singh
BACKGROUND: The presence of intraocular eyelashes following penetrating eye injury or ocular surgery is relatively uncommon. The response of the eye to intraocular eyelashes is variable. The eyelash may be symptomatic or may remain asymptomatic for long periods. OBJECTIVE: We report a case with two intraocular eyelashes and an iris cyst after 2 years of asymptomatic period following penetrating eye injury. CASE PRESENTATION: A 24-year-old male presented with decreased vision in the left eye which he had noticed for the previous 2 weeks...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28355453/dermoscopic-clues-for-diagnosing-melanomas-that-resemble-seborrheic-keratosis
#7
Cristina Carrera, Sonia Segura, Paula Aguilera, Massimiliano Scalvenzi, Caterina Longo, Alicia Barreiro, Paolo Broganelli, Stefano Cavicchini, Alex Llambrich, Pedro Zaballos, Luc Thomas, Josep Malvehy, Susana Puig, Iris Zalaudek
Importance: Melanomas that clinically mimic seborrheic keratosis (SK) can delay diagnosis and adequate treatment. However, little is known about the value of dermoscopy in recognizing these difficult-to-diagnose melanomas. Objective: To describe the dermoscopic features of SK-like melanomas to understand their clinical morphology. Design, Setting, and Participants: This observational retrospective study used 134 clinical and dermoscopic images of histopathologically proven melanomas in 134 patients treated in 9 skin cancer centers in Spain, France, Italy, and Austria...
June 1, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28264219/diagnosis-of-an-invisible-iris-cyst-using-autorefractometry-and-anterior-segment-optical-coherence-tomography
#8
T M Müller, P August, M Jesse, A P Lange
No abstract text is available yet for this article.
April 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28250145/development-and-reliability-of-the-omeract-thumb-base-osteoarthritis-magnetic-resonance-imaging-scoring-system
#9
Féline P B Kroon, Philip G Conaghan, Violaine Foltz, Frédérique Gandjbakhch, Charles Peterfy, Iris Eshed, Harry K Genant, Mikkel Østergaard, Margreet Kloppenburg, Ida K Haugen
OBJECTIVE: To develop the Outcome Measures in Rheumatology (OMERACT) thumb base osteoarthritis (OA) magnetic resonance imaging (MRI) scoring system (TOMS) for the assessment of inflammatory and structural abnormalities in this hand OA subset, and test its cross-sectional reliability. METHODS: Included features and their scaling were agreed upon by members of the OMERACT MRI Task Force using the Hand OA MRI scoring system as a template. A reliability exercise was performed in which 3 readers participated, using a preliminary atlas with examples to facilitate reading...
March 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28216527/usefulness-of-intraoperative-cone-beam-ct-images-on-video-assisted-thoracic-surgery
#10
Harutaka Hisano, Tohru Sakuragi, Yoshinobu Kakiuchi, Satoshi Takita, Yuuji Takeda, Shigeki Morita, Hiroyuki Irie
For the resection of pulmonary ground glass opacity (GGO) or non-palpable nodule on video-assisted thoracic surgery (VATS), preoperative computed tomography (CT)-guided VATS marker pricking is usually performed. Recently, air embolisms after VATS marker pricking have been reported to be serious problems. The purpose of this study was to evaluate the usefulness of intraoperative cone beam CT images on VATS to avoid preoperative VATS marker pricking. The CT number of the both GGO and nodule indicate the range from -200 to -800 HU in general...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28209236/epithelial-downgrowth-report-of-2-cases-diagnosed-by-ocular-biopsy
#11
REVIEW
Hershel R Patel, Curtis E Margo
Epithelial downgrowth is an uncommon complication of ocular surgery or adverse consequence of accidental trauma, caused by surface squamous epithelium that has gained access to the inner compartments of the eye. Once embedded in the eye, squamous epithelium spreads over contiguous structures, interfering with normal aqueous outflow and vision. The pursuit of improved therapies is ongoing, but the greatest chance of preventing blindness is with early recognition. Two cases of epithelial downgrowth diagnosed from a corneal button and an iris biopsy are presented to familiarize pathologists with this disorder...
February 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28161919/cysts-of-the-iris-pigment-epithelium-what-is-new-and-interesting-the-2016-jose-rizal-international-medal-lecture
#12
REVIEW
Jerry A Shields, Carol L Shields
PURPOSE: Cysts of the iris pigment epithelium (IPE) can involve the pupillary margin, midzone, or peripheral location or can be free-floating in the aqueous or vitreous or lodged in the anterior chamber angle. Avariant of IPE cyst, known as iris flocculi, can be a marker for systemic thoracic aneurysm. DESIGN: Review of IPE cysts and description of new observations of the lesions. METHODS: Review of IPE cysts. RESULTS: Lesions in 672 eyes were classified as of the pupillary margin (n = 49; 7%), midzone (n = 188; 28%), peripheral (n = 424; 63%), or dislodged/free-floating (n = 11; 2%)...
January 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28128847/free-floating-iris-cyst-in-the-anterior-chamber
#13
Kara M Cavuoto, Victor Villegas
No abstract text is available yet for this article.
January 1, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27856029/optical-coherence-tomography-angiography-characteristics-of-iris-melanocytic-tumors
#14
Alison H Skalet, Yan Li, Chen D Lu, Yali Jia, ByungKun Lee, Lennart Husvogt, Andreas Maier, James G Fujimoto, Charles R Thomas, David Huang
PURPOSE: To evaluate tumor vasculature with optical coherence tomography angiography (OCTA) in malignant iris melanomas and benign iris lesions. DESIGN: Cross-sectional observational clinical study. PARTICIPANTS: Patients with iris lesions and healthy volunteers. METHODS: Eyes were imaged using OCTA systems operating at 1050- and 840-nm wavelengths. Three-dimensional OCTA scans were acquired. Iris melanoma patients treated with radiation therapy were imaged again after I-125 plaque brachytherapy at 6 and 18 months...
February 2017: Ophthalmology
https://www.readbyqxmd.com/read/27843903/free-floating-pigmented-cysts-in-the-anterior-chamber-causing-ocular-hypertension
#15
Jessica S Maslin, Christopher C Teng, Miguel Materin
PURPOSE: The aim of this study was to describe the clinical and histopathological features of a 36-year-old male with hundreds of recurrent, unilateral, free-floating, pigmented cysts in the anterior chamber causing ocular hypertension. PROCEDURES: The patient was referred to ocular oncology for blurry vision of the right eye and was found to have myriad pigmented, free-floating cysts in the anterior chamber and heavy pigmentation of the angle on gonioscopy. Anterior chamber washout was performed, and the fluid recovered was sent for pathological analysis...
October 2016: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/27843899/dissecting-aortic-aneurysm-55-years-after-diagnosis-of-iris-flocculi
#16
Jerry A Shields, George N Magrath, Carol Shields, Richard Mackool, Ralph C Eagle, Hans E Grossniklaus
PURPOSE: The aim of this study is to report the clinical features, imaging studies, surgical removal, and pathology of congenital iris flocculi in a patient who developed a life-threatening dissecting aortic aneurysm after 55 years of follow-up. METHODS: Documentation with iris photography was performed from age 18 to 55 years, at which time anterior segment optical coherence tomography (OCT) was performed. At the time of subsequent cataract surgery, the iris flocculi were removed in each eye and submitted for light and electron microscopy...
October 2016: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/27625966/iris-pigment-epithelial-cysts-in-a-newborn
#17
Shabnam Zargar, Kevin John Prendiville, Eladio Martinez
PURPOSE: We report a case of iris pigment epithelial cysts in a newborn and discuss the importance of an accurate diagnosis for prevention of amblyopia. METHODS: We describe a case of an abnormal red reflex seen on a newborn exam. RESULTS: A full-term female born via normal spontaneous vaginal delivery without any complications was seen in the newborn nursery. She was noted to have an abnormal eye exam. Pupils were large with circular dark excrescences of the iris pigment epithelium...
2016: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/27546162/-congenital-iris-cyst
#18
A-L Rémond, B Bodaghi, P Le Hoang
No abstract text is available yet for this article.
September 2016: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/27488998/acute-kidney-injury-induces-hallmarks-of-polycystic-kidney-disease
#19
Almira Kurbegovic, Marie Trudel
Acute kidney injury (AKI) and autosomal dominant polycystic kidney disease (ADPKD) are considered separate entities that both frequently cause renal failure. Since ADPKD appears to depend on a polycystin-1 (Pc1) or Pc2 dosage mechanism, we investigated whether slow progression of cystogenesis in two Pkd1 transgenic mouse models can be accelerated with moderate ischemia-reperfusion injury (IRI). Transient unilateral left ischemic kidneys in both nontransgenic and transgenic mice reproducibly develop tubular dilatations, cysts, and typical PKD cellular defects within 3 mo post-IRI...
October 1, 2016: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/27440405/clinical-behavior-of-intraocular-teratoid-medulloepithelioma-in-two-related-quarter-horses
#20
Caroline S Monk, William F Craft, Jeffrey R Abbott, Lisa L Farina, Sarah M Reuss, Sarah L Czerwinski, Dennis E Brooks, Caryn E Plummer
The objective of this paper is to describe clinical behavior, histopathologic features, and immunohistochemical staining of two-related horses with intraocular teratoid medulloepithelioma. Two-related Quarter Horses with similar intraocular masses presented to the UF-CVM Comparative Ophthalmology Service for evaluation and treatment. The first horse, a 3-year-old gelding, had glaucoma and a cyst-like mass in the anterior chamber. Enucleation was performed. Histopathology revealed a teratoid medulloepithelioma...
July 20, 2016: Veterinary Ophthalmology
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