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https://www.readbyqxmd.com/read/26401401/use-of-household-ingredients-as-complementary-medicines-for-perceived-hypoglycemic-benefit-among-sri-lankan-diabetic-patients-a-cross-sectional-survey
#1
Arjuna Bandara Medagama, Danusha Senadhira
BACKGROUND: Biologic based therapies are frequently used as complementary medicines in diabetes. The aim of this study was to identify the commonly used herbal remedies and their preparations in Sri Lankan patients with Type 2 diabetes. METHODS: This is a descriptive, cross-sectional study on 220 diabetic patients using herbal remedies for perceived glycemic benefit. RESULTS: All the patients used their regular conventional medications together with herbal remedies...
April 2015: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/26384019/identification-of-novel-aldose-reductase-inhibitors-from-spices-a-molecular-docking-and-simulation-study
#2
Priya Antony, Ranjit Vijayan
Hyperglycemia in diabetic patients results in a diverse range of complications such as diabetic retinopathy, neuropathy, nephropathy and cardiovascular diseases. The role of aldose reductase (AR), the key enzyme in the polyol pathway, in these complications is well established. Due to notable side-effects of several drugs, phytochemicals as an alternative has gained considerable importance for the treatment of several ailments. In order to evaluate the inhibitory effects of dietary spices on AR, a collection of phytochemicals were identified from Zingiber officinale (ginger), Curcuma longa (turmeric) Allium sativum (garlic) and Trigonella foenum graecum (fenugreek)...
2015: PloS One
https://www.readbyqxmd.com/read/26229535/mycobiota-and-natural-incidence-of-aflatoxins-ochratoxin-a-and-citrinin-in-indian-spices-confirmed-by-lc-ms-ms
#3
Punam Jeswal, Dhiraj Kumar
Nine different Indian spices (red chilli, black pepper, turmeric, coriander, cumin, fennel, caraway, fenugreek, and dry ginger) commonly cultivated and highly used in India were analysed for natural occurrence of toxigenic mycoflora and aflatoxins (AFs), ochratoxin A (OTA), and citrinin (CTN) contamination. Aspergillus flavus and Aspergillus niger were the most dominant species isolated from all types of spices. Red chilli samples were highly contaminated with aflatoxins (85.4%) followed by dry ginger (77.7%)...
2015: International Journal of Microbiology
https://www.readbyqxmd.com/read/26147513/anti-cholelithogenic-potential-of-dietary-spices-and-their-bioactives
#4
Krishnapura Srinivasan
Dietary hypocholesterolemic spices - curcumin (active compound of turmeric (Curcuma longa) and capsaicin (active compound of red pepper (Capsicum annuum), the active principles of spices - turmeric (Curcuma longa) and red pepper (Capsicum annuum), fenugreek (Trigonella foenum-graecum) seeds, garlic (Allium sativum), and onion (Allium cepa) are documented to have anti-cholelithogenic property in animal model. These spices prevent the induction of cholesterol gallstones by lithogenic high cholesterol diet and also regress the pre-established cholesterol gallstones, by virtue of their hypolipidemic potential...
July 6, 2015: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/26132858/natural-products-for-the-treatment-of-type-2-diabetes-mellitus
#5
REVIEW
José Luis Ríos, Flavio Francini, Guillermo R Schinella
Type 2 diabetes mellitus is a metabolic disease characterized by persistent hyperglycemia. High blood sugar can produce long-term complications such as cardiovascular and renal disorders, retinopathy, and poor blood flow. Its development can be prevented or delayed in people with impaired glucose tolerance by implementing lifestyle changes or the use of therapeutic agents. Some of these drugs have been obtained from plants or have a microbial origin, such as galegine isolated from Galega officinalis, which has a great similarity to the antidiabetic drug metformin...
August 2015: Planta Medica
https://www.readbyqxmd.com/read/25872425/development-and-validation-of-a-triplex-real-time-pcr-assay-for-the-simultaneous-detection-of-three-mustard-species-and-three-celery-varieties-in-food
#6
Monika Palle-Reisch, Rupert Hochegger, Margit Cichna-Markl
The paper presents a triplex real-time PCR assay allowing the simultaneous detection of three mustard species (white, black and brown mustard) and three celery varieties (celery roots, celery stalks and leaf celery) in foodstuffs. The triplex assay does not show cross-reactivity with other Brassicaceae. Low cross-reactivities were observed with fenugreek, cumin, ginger, caraway, turmeric, lovage and rye, the ΔCt values were, however, ⩾ 12 compared to positive controls. The triplex assay allows the detection of traces of DNA of the allergenic components in spite of an excess of the other DNA templates...
October 1, 2015: Food Chemistry
https://www.readbyqxmd.com/read/25747463/postharvest-processing-and-benefits-of-black-pepper-coriander-cinnamon-fenugreek-and-turmeric-spices
#7
S Balasubramanian, P Roselin, K K Singh, John Zachariah, S N Saxena
Spices are prime source for flavor, aroma, and taste in cuisines and play an active role as medicines due to their high antioxidant properties. As medicine or food, the importance of spices cannot be overemphasized. The medicinal values of spices are very well established in treating various ailments like cancer, fever, malaria, stomach offset, nausea, and many more. A spice may be available in several forms: fresh, whole dried, or pre-ground dried which requires further processing to be utilized in the form of value-added product...
July 26, 2016: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/24491701/development-and-validation-of-a-duplex-real-time-pcr-assay-for-the-simultaneous-detection-of-three-mustard-species-sinapis-alba-brassica-nigra-and-brassica-juncea-in-food
#8
Monika Palle-Reisch, Margit Cichna-Markl, Rupert Hochegger
The paper presents a duplex real-time PCR assay for the simultaneous detection of three potentially allergenic mustard species commonly used in food: white mustard (Sinapis alba), black mustard (Brassica nigra) and brown mustard (Brassica juncea). White mustard is detected in the "green" and black/brown mustard in the "yellow" channel. The duplex real-time PCR assay does not show cross-reactivity with other Brassicaceae species including broccoli, cauliflower, radish and rapeseed. Low cross-reactivities (difference in the Ct value ⩾ 11...
June 15, 2014: Food Chemistry
https://www.readbyqxmd.com/read/24188307/antioxidant-potential-of-spices-and-their-active-constituents
#9
REVIEW
K Srinivasan
Excessive free radical generation overbalancing the rate of their removal leads to oxidative stress. Oxidative stress has been implicated in the etiology of cardiovascular disease, inflammatory diseases, cancer, and other chronic diseases. Antioxidants are compounds that hinder the oxidative processes and thereby delay or suppress oxidative stress. There is a growing interest in natural antioxidants found in plants. Herbs and spices are most important targets to search for natural antioxidants from the point of view of safety...
2014: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/23364205/dietary-spices-as-beneficial-modulators-of-lipid-profile-in-conditions-of-metabolic-disorders-and-diseases
#10
Krishnapura Srinivasan
Spices are valued for their medicinal properties besides their use as food adjuncts to enhance the sensory quality of food. Dietary garlic, onion, fenugreek, red pepper, turmeric, and ginger have been proven to be effective hypocholesterolemics in experimentally induced hypercholesterolemia. The hypolipidemic potential of fenugreek in diabetic subjects and of garlic and onion in humans with induced lipemia has been demonstrated. Capsaicin and curcumin - the bioactive compounds of red pepper and turmeric - are documented to be efficacious at doses comparable to usual human intake...
April 25, 2013: Food & Function
https://www.readbyqxmd.com/read/23265498/development-and-validation-of-a-real-time-pcr-method-for-the-simultaneous-detection-of-black-mustard-brassica-nigra-and-brown-mustard-brassica-juncea-in-food
#11
Monika Palle-Reisch, Martina Wolny, Margit Cichna-Markl, Rupert Hochegger
The paper presents a real-time PCR method allowing the simultaneous detection of traces of black mustard (Brassica nigra) and brown mustard (Brassica juncea) in food. The primers and the probe target the B. nigra partial RT gene for reverse transcriptase from gypsy-like retroelement 13G42-26. The real-time PCR method does not show any cross-reactivity with other Brassicaceae species with the exception of white mustard. Low cross-reactivities with cinnamon, cumin, fenugreek, ginger, rye and turmeric can be ignored because in common mustard containing foodstuffs these biological species are present in very low amounts...
May 1, 2013: Food Chemistry
https://www.readbyqxmd.com/read/22149093/cancer-cell-signaling-pathways-targeted-by-spice-derived-nutraceuticals
#12
REVIEW
Bokyung Sung, Sahdeo Prasad, Vivek R Yadav, Bharat B Aggarwal
Extensive research within the last half a century has revealed that cancer is caused by dysregulation of as many as 500 different gene products. Most natural products target multiple gene products and thus are ideally suited for prevention and treatment of various chronic diseases, including cancer. Dietary agents such as spices have been used extensively in the Eastern world for a variety of ailments for millennia, and five centuries ago they took a golden journey to the Western world. Various spice-derived nutraceuticals, including 1'-acetoxychavicol acetate, anethole, capsaicin, cardamonin, curcumin, dibenzoylmethane, diosgenin, eugenol, gambogic acid, gingerol, thymoquinone, ursolic acid, xanthohumol, and zerumbone derived from galangal, anise, red chili, black cardamom, turmeric, licorice, fenugreek, clove, kokum, ginger, black cumin, rosemary, hop, and pinecone ginger, respectively, are the focus of this review...
2012: Nutrition and Cancer
https://www.readbyqxmd.com/read/22119904/dietary-agents-in-the-prevention-of-alcohol-induced-hepatotoxicty-preclinical-observations
#13
REVIEW
Arnadi Ramachandrayya Shivashankara, Aysha Azmidah, Raghavendra Haniadka, Manoj Ponadka Rai, Rajesh Arora, Manjeshwar Shrinath Baliga
Long term alcohol consumption is one of the important causes for liver failure and death. To complicate the existing problem there are no dependable hepatoprotective drugs and a large number of patients prefer using complementary and alternative medicines for treating and managing hepatic complications. Almost 25 centuries ago, Hippocrates, the father of medicine, proclaimed "Let food be thy medicine and medicine be thy food." Exploring the association between diet and health continues even today. Preclinical studies carried out in the recent past have shown that the commonly used dietary agents like Allium sativum (garlic), Camellia sinensis (tea), Curcuma longa (turmeric), Emblica officinalis (Indian gooseberry), Ferula asafoetida (asafoetida), Garcinia cambogia (Malabar tamarind), Glycine max (soyabean), Murraya koenigii (curry leaves), Piper betle (beetle leaf), Prunus armeniaca (apricot), Ocimum gratissimum (wild basil), Theobroma cacao (cocoa), Trigonella foenum-graecum (fenugreek) and Vitis vinifera (grapes) protect against ethanol-induced hepatotoxicity...
February 2012: Food & Function
https://www.readbyqxmd.com/read/19922253/indigenous-drugs-in-ischemic-heart-disease-in-patients-with-diabetes
#14
REVIEW
Shridhar Dwivedi, Amitesh Aggarwal
BACKGROUND: India is currently facing the silent epidemic of ischemic heart disease, type 2 diabetes mellitus (T2DM), hypertension, and stroke. Both diabetes and ischemic heart disease appear in Indian people a decade earlier compared to whites. The recent evidence that certain medicinal plants possess hypoglycemic, lipid-lowering, and immunomodulating properties on account of their rich flavonoid and/or other glucose-lowering active constituents merits scientific scrutiny in this regard...
November 2009: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/19769367/stability-of-lipid-constituents-in-radiation-processed-fenugreek-seeds-and-turmeric-role-of-phenolic-antioxidants
#15
Suchandra Chatterjee, Prasad Shekhar Variyar, Arun Sharma
Impact of radiation processing on the lipid profile of fenugreek and turmeric was investigated. Oleic and linoleic acid were the dominant fatty acids with an appreciable amount of linolenic acid in both cases. Gamma-irradiation did not bring about any significant changes in the fatty acid profile of these spices despite a high content of unsaturation. The ability of aqueous methanolic extract of both spices with high phenolic content to prevent lipid peroxidation suggests a possible role of phenolic constituents in preventing lipid radiolysis...
October 14, 2009: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/18729454/influence-of-food-acidulants-and-antioxidant-spices-on-the-bioaccessibility-of-beta-carotene-from-selected-vegetables
#16
Supriya Veda, Kalpana Platel, Krishnapura Srinivasan
Four common food acidulants--amchur, lime, tamarind, and kokum--and two antioxidant spices--turmeric and onion--were examined for their influence on the bioaccessibility of beta-carotene from two fleshy and two leafy vegetables. Amchur and lime generally enhanced the bioaccessibility of beta-carotene from these test vegetables in many instances. Such an improved bioaccessibility was evident in both raw and heat-processed vegetables. The effect of lime juice was generally more pronounced than that of amchur...
September 24, 2008: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/18612945/potential-of-spice-derived-phytochemicals-for-cancer-prevention
#17
REVIEW
Bharat B Aggarwal, Ajaikumar B Kunnumakkara, Kuzhuvelil B Harikumar, Sheeja T Tharakan, Bokyung Sung, Preetha Anand
Although spices have been used for thousands of years and are known for their flavor, taste and color in the food, they are not usually recognized for their medicinal value. Extensive research within the last two decades from our laboratory and others has indicated that there are phytochemicals present in spices that may prevent various chronic illnesses including cancerous, diabetic, cardiovascular, pulmonary, neurological and autoimmune diseases. For instance, the potential of turmeric (curcumin), red chilli (capsaicin), cloves (eugenol), ginger (zerumbone), fennel (anethole), kokum (gambogic acid), fenugreek (diosgenin), and black cumin (thymoquinone) in cancer prevention has been established...
October 2008: Planta Medica
https://www.readbyqxmd.com/read/18296352/traditional-indian-spices-and-their-health-significance
#18
REVIEW
Kamala Krishnaswamy
India has been recognized all over the world for spices and medicinal plants. Both exhibit a wide range of physiological and pharmacological properties. Current biomedical efforts are focused on their scientific merits, to provide science-based evidence for the traditional uses and to develop either functional foods or nutraceuticals. The Indian traditional medical systems use turmeric for wound healing, rheumatic disorders, gastrointestinal symptoms, deworming, rhinitis and as a cosmetic. Studies in India have explored its anti-inflammatory, cholekinetic and anti-oxidant potentials with the recent investigations focusing on its preventive effect on precarcinogenic, anti-inflammatory and anti atherosclerotic effects in biological systems both under in vitro and in vivo conditions in animals and humans...
2008: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/16563357/molecular-targets-of-dietary-agents-for-prevention-and-therapy-of-cancer
#19
REVIEW
Bharat B Aggarwal, Shishir Shishodia
While fruits and vegetables are recommended for prevention of cancer and other diseases, their active ingredients (at the molecular level) and their mechanisms of action less well understood. Extensive research during the last half century has identified various molecular targets that can potentially be used not only for the prevention of cancer but also for treatment. However, lack of success with targeted monotherapy resulting from bypass mechanisms has forced researchers to employ either combination therapy or agents that interfere with multiple cell-signaling pathways...
May 14, 2006: Biochemical Pharmacology
https://www.readbyqxmd.com/read/16437723/bactericidal-and-anti-adhesive-properties-of-culinary-and-medicinal-plants-against-helicobacter-pylori
#20
Rachel O'Mahony, Huda Al-Khtheeri, Deepaka Weerasekera, Neluka Fernando, Dino Vaira, John Holton, Christelle Basset
AIM: To investigate the bactericidal and anti-adhesive properties of 25 plants against Helicobacter pylori (H. pylori). METHODS: Twenty-five plants were boiled in water to produce aqueous extracts that simulate the effect of cooking. The bactericidal activity of the extracts was assessed by a standard kill-curve with seven strains of H. pylori. The anti-adhesive property was assessed by the inhibition of binding of four strains of FITC-labeled H. pylori to stomach sections...
December 21, 2005: World Journal of Gastroenterology: WJG
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