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Living kidney donation

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https://www.readbyqxmd.com/read/27908469/-ethics-and-kidney-transplants-with-living-donors
#1
Marie-France Mamzer Bruneel
The ethical debate surrounding transplant practices questions our societies. International recommendations set out numerous precautions which must be taken to ensure that donors act with their free will. While in most countries, including France, organ donation is a voluntary and non-commercial act, a black market exists in the world resulting in the trafficking of organs and tragic transplant tourism.
December 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/27894119/trajectories-and-predictors-of-allograft-dysfunction-after-renal-transplantation-in-children
#2
Vandréa Carla de Souza, Muriel Rabilloud, Pierre Cochat, Mario Bernardes Wagner, Clotilde Druck Garcia, Bruno Ranchin, Jean Iwaz, Luciano Selistre, Laurence Dubourg
BACKGROUND: The survival rates of renal transplant children are indeed on the rise, but it is still important to ensure that there is optimal renal function in these children in all their future growing years. The number of functioning nephrons and the graft ability to adapt to an increasing demand during body growth seem to be the most important factors for long-term allograft function. This study examined the long-term change in the glomerular filtration rate in a pediatric kidney transplant cohort and the importance of the recipient and donor ages in predicting transplant outcome...
November 29, 2016: American Journal of Nephrology
https://www.readbyqxmd.com/read/27889296/donor-and-recipient-views-on-their-relationship-in-living-kidney-donation-thematic-synthesis-of-qualitative-studies
#3
Angelique F Ralph, Phyllis Butow, Camilla S Hanson, Steve J Chadban, Jeremy R Chapman, Jonathan C Craig, John Kanellis, Grant Luxton, Allison Tong
BACKGROUND: Many donors and recipients report an improved relationship after transplantation; however, tension, neglect, guilt, and proprietorial concern over the recipient can impede donor and recipient well-being and outcomes. We aimed to describe donor and recipient expectations and experiences of their relationship in the context of living kidney donation. STUDY DESIGN: Thematic synthesis of qualitative studies. SETTING & POPULATION: Living kidney donors and recipients...
November 23, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27888569/providing-coverage-for-the-unique-life-long-health-care-needs-of-living-kidney-donors-within-the-framework-of-financial-neutrality
#4
John S Gill, Francis Delmonico, Scott Klarenbach, Alexander Morgan Capron
Organ donation should neither enrich nor impose financial burdens on donors. We describe the scope of health care required for all living kidney donors that reflects contemporary understanding of long-term donor health outcomes, propose an approach to identify donor health conditions which should be covered within the framework of financial neutrality, and propose strategies to pay for this care. Despite the Affordable Care Act in the United States, donors continue to have inadequate coverage for important health conditions that are either donation related or may compromise post-donation kidney function...
November 26, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/27888522/barriers-to-the-use-of-a-federal-travel-grant-by-living-kidney-donors
#5
Rebecca Hays, Amy Elaine Thomas, Erin Mathias, Joshua Mezrich, Didier A Mandelbrot
Living organ donation involves significant out of pocket costs, which burden donor candidates and may be an obstacle to donation. There is a single US grant (the National Living Donor Assistance Center- NLDAC) to cover live donor travel costs. Though there may be center-specific variability in grant utilization, prospective donors - and their intended recipients- must also meet eligibility criteria. In fact, the NLDAC grant is used by <10% of US live donors annually. We studied 154 consecutive kidney donor clinic evaluations (11/01/14-08/30/15) to determine eligibility and usage patterns during the evaluation process...
November 26, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27878047/optimal-surgical-strategies-in-living-kidney-donation
#6
Omar Ali, Alp Sener
No abstract text is available yet for this article.
August 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27878046/back-to-back-comparison-of-mini-open-vs-laparoscopic-technique-for-living-kidney-donation
#7
Christie Rampersad, Premal Patel, Joshua Koulack, Thomas McGregor
INTRODUCTION: Laparoscopic living donor nephrectomy is the standard of care at high-volume renal transplant centres, with benefits over the open approach well-documented in the literature. Herein, we present a retrospective analysis of our single-institution donor nephrectomy series comparing the mini-open donor nephrectomy (mini-ODN) to the laparoscopic donor nephrectomy (LDN) with regards to operative, donor, and recipient outcomes. METHODS: From 2007-2011, there were 89 cases of mini-ODN, at which point our centre transitioned to LDN; 94 cases were performed from 2011-2014...
August 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27862900/long-term-renal-allograft-survival-after-sequential-liver-kidney-transplantation-from-a-single-living-donor
#8
Kumiko Kitajima, Yuichi Ogawa, Katsuyuki Miki, Kotaro Kai, Akihito Sannomiya, Kazuhiro Iwadoh, Toru Murakami, Ichiro Koyama, Ichiro Nakajima, Shohei Fuchinoue
Background Combined liver-kidney transplantation (CLKT) is well-established as a definitive therapy with the potential to provide complete recovery for certain liver-kidney diseases, although the results might be contingent on the cause of transplantation. The purposes of the present study were to review the long-term outcome of renal allografts in CLKT patients from single living donors and to investigate the beneficial factors, compared with solitary renal transplantation. Materials and Methods Thirteen patients underwent sequential liver (LTx) and kidney (KTx) transplantations from single living donors...
November 10, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/27815930/unique-considerations-when-managing-hypertension-in-the-transplant-patient
#9
Donald Mitema, Carrie Schinstock
For the select fortunate recipients of organ transplants, transplantation affords the rare opportunity for a new life. Given the scarcity of organs for transplantation, it is imperative that the health of transplant recipients be optimized in order to fully benefit from this gift of life. Unfortunately, hypertension is highly prevalent in the transplant population and it is considered a major cardiovascular risk factor contributing to mortality and morbidity in this population. In this chapter, we expound on the epidemiology, unique pathophysiology, evaluation, and management of hypertension as it pertains to the solid organ transplant recipient...
November 5, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27803919/increasing-access-to-kidney-transplantation-for-sensitized-recipient-through-three-way-kidney-paired-donation-with-desensitization-the-first-indian-report
#10
Vivek B Kute, Himanshu V Patel, Pankaj R Shah, Pranjal R Modi, Veena R Shah, Sayyed J Rizvi, Bipin C Pal, Manisha P Modi, Priya S Shah, Umesh T Varyani, Pavan S Wakhare, Saiprasad G Shinde, Viajay A Ghodela, Minaxi H Patel, Varsha B Trivedi, Hargovind L Trivedi
The combination of kidney paired donation (KPD) with desensitization represents a promising method of increasing the rate of living donor kidney transplantation (LDKT) in immunologically challenging patients. Patients who are difficult to match and desensitize due to strong donor specific antibody are may be transplanted by a combination of desensitization and KPD protocol with more immunologically favorable donor. We present our experience of combination of desensitization protocol with three-way KPD which contributed to successful LDKT in highly sensitized end stage renal disease patient...
October 16, 2016: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/27800047/expanding-living-kidney-donor-criteria-with-ex-vivo-surgery-for-renal-anomalies
#11
Thomas B McGregor, Christie Rampersad, Premal Patel
INTRODUCTION: Renal transplantation remains the gold standard treatment for end-stage renal disease, with living donor kidneys providing the best outcomes in terms of allograft survival. As the number of patients on the waitlist continues to grow, solutions to expand the donor pool are ongoing. A paradigm shift in the eligibility of donors with renal anomalies has been looked at as a potential source to expand the living donor pool. We sought to determine how many patients presented with anatomic renal anomalies at our transplant centre and describe the ex-vivo surgical techniques used to render these kidneys suitable for transplantation...
September 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27795875/identification-of-a-patient-population-previously-not-considered-for-organ-donation
#12
Brad Barrois
For the foreseeable future, more individuals will need a kidney than there are kidneys available for transplant. This is not a new issue, and it is one that will not likely be solved anytime soon. While recent initiatives have focused on efficiently allocating kidneys in order to maximize supply, a shortage will remain.  Currently, organs are made available for transplant through three different processes: donation after brain death declaration (BD), donation after circulatory death (DCD), and living donation (one healthy individual donates to a person in need)...
September 26, 2016: Curēus
https://www.readbyqxmd.com/read/27779281/policy-options-for-increasing-the-supply-of-transplantable-kidneys-in-singapore
#13
Jia Loon Chong
Kidney transplantation is the preferred treatment for eligible end-stage renal disease patients. However, the supply of donated kidneys has been consistently insufficient to meet the transplantation requirements of the population. In this paper, I discuss the feasibility of several policy options that engage potential donors or key individuals in a Singapore context, including financial and non-financial incentives for deceased/living organ donors and their families, improving actualisation rates of both donation after brain death, donation after cardiac death through quality improvement programmes and remuneration schemes, and a media platform for directed organ donation...
October 2016: Singapore Medical Journal
https://www.readbyqxmd.com/read/27776143/defining-priorities-for-future-research-results-of-the-uk-kidney-transplant-priority-setting-partnership
#14
Simon R Knight, Leanne Metcalfe, Katriona O'Donoghue, Simon T Ball, Angela Beale, William Beale, Rachel Hilton, Keith Hodkinson, Graham W Lipkin, Fiona Loud, Lorna P Marson, Peter J Morris
BACKGROUND: It has been suggested that the research priorities of those funding and performing research in transplantation may differ from those of end service users such as patients, carers and healthcare professionals involved in day-to-day care. The Kidney Transplant Priority Setting Partnership (PSP) was established with the aim of involving all stakeholders in prioritising future research in the field. METHODS: The PSP methodology is as outlined by the James Lind Alliance...
2016: PloS One
https://www.readbyqxmd.com/read/27742330/donate-a-piece-of-liver-is-this-an-option-accepted-by-future-nurses-of-pomeranian-medical-university-in-poland
#15
M Mikla, A Rios, A Lopez-Navas, B Gorzkowicz, D Kilanska, L Martinez-Alarcón, G Ramis, P Ramirez, M J Lopez Montesinos
BACKGROUND: Liver transplantation from living donors (LLD) has become a viable and important source of liver grafts. The objective of this study was to analyze the attitude of nursing students at the Pomeranian Medical University in Poland on donation of live liver, and to determine the factors that affect it. METHODS: Academic year 2011-2012, nursing students at a university in Poland, sampling points in 5 compulsory-attendance nursing courses with a completion rate of 80%, validated questionnaire (PCID-DVH Rios) filled out anonymously and self-administered...
September 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27742310/increasing-use-of-the-expanded-criteria-for-living-kidney-donation-and-good-outcomes-of-living-kidney-donors-in-korea
#16
H J Lim, E Jambaldorj, Y Lee, S S Kang, T Y Koo, C Ahn, J Yang
BACKGROUND: Donor shortage for kidney transplantation may increase the number of expanded-criteria living donors (ECLDs). We investigated recent trends for ECLD use and the long-term outcomes of living kidney donors. METHODS: We retrospectively analyzed medical records of 1,144 living kidney donors who donated at the Seoul National University Hospital from 1993 to 2015. The expanded criteria for living donation allow the following: age ≥60 years, body mass index >30 kg/m(2), history of hypertension, estimated glomerular filtration rate <80 mL/min, proteinuria or microscopic hematuria, and fasting glucose >100 mg/dL...
September 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27720629/-living-kidney-donation
#17
M-O Timsit, F Kleinclauss, M F Mamzer Bruneel, R Thuret
OBJECTIVES: To review ethical, legal and technical aspects of living kidney donor surgery. MATERIAL AND METHODS: An exhaustive systematic review of the scientific literature was performed in the Medline database (http://www.ncbi.nlm.nih.gov) and Embase (http://www.embase.com) using different associations of the following keywords: Donor nephrectomy; Kidney paired donation; Kidney transplantation; Laparoscopic nephrectomy; Living donor; Organs trafficking; Robotic assisted nephrectomy; Vaginal extraction...
October 6, 2016: Progrès en Urologie
https://www.readbyqxmd.com/read/27717017/five-year-follow-up-after-live-donor-nephrectomy-cross-sectional-and-longitudinal-analysis-of-a-prospective-cohort-within-the-era-of-extended-donor-eligibility-criteria
#18
Shiromani Janki, Leonienke F C Dols, Reinier Timman, Evalyn E A P Mulder, Ine M M Dooper, Jacqueline van de Wetering, Jan N M IJzermans
To establish the outcome of live kidney donors 5 years after donation, we investigated the risk for progressive renal function decline and quality of life (QoL). Data on estimated glomerular filtration rate (eGFR), creatinine, hypertension, QoL and survival were assessed in a prospective cohort of 190 donors, who donated between 2008 and 2010. Data were available for >90%. The mean age predonation was 52.8 ± 11.5 years, 30 donors having pre-existent hypertension. The mean follow-up was 5.1 ± 0.9 years...
October 7, 2016: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/27704243/optimizing-a-living-kidney-donation-program-transition-to-hand-assisted-retroperitoneoscopic-living-donor-nephrectomy-and-introduction-of-a-passive-polarizing-three-dimensional-display-system
#19
Roger Wahba, Robert Kleinert, Martin Hellmich, Nadine Heiermann, Georg Dieplinger, Hans A Schlößer, Denise Buchner, Christine Kurschat, Dirk L Stippel
BACKGROUND: Optimizing a living kidney donation program is important to guarantee a high grade of acceptance among potential donors. Hand-assisted retroperitoneoscopic donor nephrectomy (HARP) is an alternative to the open anterior approach (AA) technique. Problems associated to the learning curve could hinder a transition. 3D display technique seems to ease minimally invasive surgery. Aim of this study was to evaluate the learning curve during the transition from AA to HARP and the influence of the 3D display system on the established technique...
October 4, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27659295/iranian-kidney-market-in-limbo-a-commentary-on-the-ambiguous-lessons-of-the-iranian-model-of-paid-living-kidney-donation
#20
Hojjat Soofi
Sigrid Fry-Revere's The Kidney Sellers: A Journey of Discovery in Iran, an allegedly first-hand examination of the Iranian paid kidney donation model, has been criticized by Koplin in an essay formerly published in the Monash Bioethics Review. Koplin especially challenges Fry-Revere's claim that financially compensating kidney vendors might facilitate altruistic kidney donation. The current situation in Iran, according to Koplin, suggests that the market model has undermined altruistic donation. On this point, this commentary tries to show that healthcare policymakers in Iran no longer see the Iranian paid kidney donation model as a sustainable and ethically justifiable status quo...
September 22, 2016: Monash Bioethics Review
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