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https://www.readbyqxmd.com/read/28731808/clinical-practice-in-pet-ct-for-the-management-of-head-and-neck-squamous-cell-cancer
#1
Reema Goel, William Moore, Baran Sumer, Saad Khan, David Sher, Rathan M Subramaniam
OBJECTIVE: The purpose of this article is to summarize the evidence for the value of PET/CT for the management of patients with head and neck squamous cell cancer and suggest best clinical practices. CONCLUSION: FDG PET/CT is a valuable imaging tool for identifying unknown primary tumors in patients with known cervical node metastases leading to management change and is the standard of care for the initial staging of stage III and IV head and neck squamous cell carcinomas (HNSCCs), for assessing therapy response when performed at least 12 weeks after chemoradiation therapy, and for avoiding unnecessary planned neck dissection...
August 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28731009/interlesional-flip-flop-between-68-ga-dotatate-and-fdg-pet-ct-in-thyroglobulin-elevated-negative-iodine-scintigraphy-tenis-syndrome
#2
Sandip Basu, Ashwini Kalshetty, Preeti Fargose
No abstract text is available yet for this article.
January 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28730618/undiagnosed-chronic-temporomandibular-joiny-pain-making-a-case-for-fdg-pet-ct
#3
Dwight D Rice, Kenneth Abramovitch, Susan Roche, Cherie A Cora, Karina D Torralba, Heidi L Christensen, Edwin L Christiansen
No abstract text is available yet for this article.
July 21, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28730266/-malignant-melanoma-current-status
#4
REVIEW
J K Winkler, K Buder-Bakhaya, A Dimitrakopoulou-Strauss, A Enk, J C Hassel
CLINICAL ISSUE: The incidence of malignant melanoma is continuously increasing. The prognosis of metastatic disease is still limited. STANDARD TREATMENT: Until a few years ago palliative chemotherapy with a limited response rate was the standard treatment for metastatic melanoma. TREATMENT INNOVATIONS: Immunotherapy and targeted therapy provide new treatment options. Immune checkpoint inhibitors have significantly improved the prognosis. DIAGNOSTIC WORK-UP: Regional lymph node sonography, computed tomography (CT) of the neck, chest and abdomen and brain magnetic resonance imaging (MRI) are routinely used...
July 20, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28729430/imaging-chemokine-receptor-cxcr4-in-chronic-infection-of-the-bone-with-68-ga-pentixafor-pet-ct-first-insights
#5
Caroline Bouter, Birgit Meller, Carsten Oliver Sahlmann, Wieland Staab, Hans Jürgen Wester, Saskia Kropf, Johannes Meller
Due to its role in infection and inflammatory processes the chemokine receptor CXCR4 might be a potent target in imaging of infectious and inflammatory diseases. The aim of this pilot study was to determine whether the CXCR4 ligand (68)Ga-Pentixafor is suitable for imaging chronic infection of the bone. Methods: The study comprises 14 patients with suspected infection of the skeleton that underwent (68)Ga-Pentixafor-(68)Ga-Pentixafor-Positron emission tomography/computed tomography(PET/CT) between 04/2015 and 02/2017 in our facility...
July 20, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28729192/butyrylcholinesterase-knockout-reduces-fibrillar-%C3%AE-amyloid-and-conserves-18-fdg-retention-in-5xfad-mouse-model-of-alzheimer-s-disease
#6
D R DeBay, G A Reid, I R Macdonald, G Mawko, S Burrell, E Martin, C V Bowen, S Darvesh
Alzheimer's disease (AD) is the most common neurodegenerative disorder causing dementia. One hallmark of the AD brain is the deposition of β-amyloid (Aβ) plaques. AD is also a state of cholinergic dysfunction and butyrylcholinesterase (BChE) associates with Aβ pathology. A transgenic mouse (5XFAD) is an aggressive amyloidosis model, producing Aβ plaques of which BChE also associates. A derived strain (5XFAD/BChE-KO), with the BChE gene knocked out, has significantly lower fibrillar Aβ than 5XFAD mice at the same age...
July 17, 2017: Brain Research
https://www.readbyqxmd.com/read/28728779/-miner-s-cap-like-solitary-frontal-bone-metastasis-from-rectal-adenocarcinoma-on-18-f-fdg-pet-ct
#7
I Banzo, I Martínez-Rodríguez, N Martínez-Amador, M Jiménez-Alonso, R Quirce, J Jiménez-Bonilla
No abstract text is available yet for this article.
July 17, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28728462/increased-binding-potential-of-brain-adenosine-a-sub-1-sub-receptor-in-chronic-stages-of-patients-with-diffuse-axonal-injury-measured-with-1-methyl-sup-11-sup-c-8-dicyclopropylmethyl-1-methyl-3-propylxanthine-pet-imaging
#8
Shihori Hayashi, Motoki Inaji, Tadashi Nariai, Keiichi Oda, Muneyuki Sakata, Jun Toyohara, Kenji Ishii, Kiichi Ishiwata, Taketoshi Maehara
The positron emission tomography (PET) radioligand for adenosine A <sub>1</sub> receptor (A1R) [1-methyl- <sup>11</sup>C] 8-dicyclopropylmethyl-1-methyl-3-propylxanthine (MPDX) has recently been developed for human brain imaging. In the present study, we evaluated the alteration of the A1R in patients with diffuse axonal injury (DAI) in chronic stage <i>in vivo</i>. Ten patients with DAI (7 men and 3 women) were included in this study. Three PET examinations were sequentially performed to measure A1R binding with <sup>11</sup>C-MPDX, glucose metabolism with <sup>18</sup>F-fluorodeoxyglucose (FDG), and central benzodiazepine receptor binding with <sup>11</sup>C-flumazenil (FMZ), decreases of <sup>11</sup>C-FMZ uptake indicate neuronal loss...
July 20, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28728300/-evaluate-the-value-of-18-f-fdg-pet-ct-imaging-in-predicting-the-mutationsin-epidermal-growth-factor-receptor-in-lung-adenocarcinoma
#9
C Y Ding, W P Yang, Z Guo, J Sun, Y Y Li, T R Li
Objective: To investigate the value of maximum Standardized Uptake Value(SUVmax), Metabolic Tumor Volume (MTV) and Total Lesion Glycolysis (TLG) calculated from (18)F-FDG PET-CT in predicting the presence of epidermal growth factor receptor (EGFR) mutations in lung adenocarcinoma. Methods: We retrospectively reviewed 137 lung adenocarcinoma patients with EGFR mutations testing and pretreatment (18)F-FDG PET-CT. Receiver Operating Characteristic (ROC) curve analysis was performed to quantify the predictive value of SUVmax、MTV、TLG...
July 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28728208/the-role-of-18f-fdg-pet-ct-scan-in-predicting-histological-type-of-thymic-epithelial-tumors-indications-and-practical-clinical-considerations
#10
Filippo Lococo
No abstract text is available yet for this article.
July 20, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28727480/pilot-study-of-propranolol-premedication-to-reduce-fdg-uptake-in-brown-adipose-tissue-on-pet-scans-of-adolescent-and-young-adult-oncology-patients
#11
Anil George, Partha Sinha, Gary Conrad, Aum A Memon, Emily V Dressler, Lars M Wagner
OBJECTIVE: Physiologic uptake of (18)F-fluorodeoxyglucose (FDG) in brown adipose tissue (adipose tissue) of cancer patients may confound interpretation of positron emission tomography (PET) scans. Uptake in adipose tissue occurs in up to half of pediatric oncology patients undergoing PET scans, and is especially common in adolescents. adipose tissue is innervated by the sympathetic nervous system, and beta blockers such as propranolol have shown efficacy in reducing adipose tissue uptake on PET scans done in older adult oncology patients...
July 20, 2017: Pediatric Hematology and Oncology
https://www.readbyqxmd.com/read/28725583/positron-emission-tomography-pet-in-primary-prostate-cancer-staging-and-risk-assessment
#12
REVIEW
Sandra Bednarova, Maria L Lindenberg, Maria Vinsensia, Chiara Zuiani, Peter L Choyke, Baris Turkbey
Prostate cancer (PCa) is one of the few neoplasms that are not well served by 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET). As a result, a number of PET tracers have been developed to target particular biological features of PCa. Such agents can be used for diagnosis, staging, identification of biochemical recurrence (BCR) and evaluation of metastatic disease. Here, we focus on primary disease and local staging. To date, magnetic resonance imaging (MRI) has proven superior to PET in the imaging of primary PCa...
June 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28724379/regulation-of-glucose-uptake-in-lymphoma-cell-lines-by-c-myc-and-pi3k-dependent-signaling-pathways-and-impact-of-glycolytic-pathways-on-cell-viability
#13
Martina Broecker-Preuss, Nina Becher-Boveleth, Andreas Bockisch, Ulrich Dührsen, Stefan Müller
BACKGROUND: Changes in glucose and energy metabolism contribute to the altered phenotype of cancer cells and are the basis for positron emission tomography with (18)F-fluoro-2-deoxy-D-glucose (FDG) to visualize tumors in vivo. The molecular background of the enhanced glucose uptake and its regulation in lymphoma cells is not fully clarified and may provide new possibilities to reverse the altered metabolism. Thus in this study we investigated regulation of glucose uptake by different signaling pathways...
July 19, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28723938/gender-differences-in-cerebral-metabolism-for-color-processing-in-mice-a-pet-mri-study
#14
Philip C Njemanze, Mathias Kranz, Mario Amend, Jens Hauser, Hans Wehrl, Peter Brust
INTRODUCTION: Color processing is a central component of mammalian vision. Gender-related differences of color processing revealed by non-invasive functional transcranial Doppler ultrasound suggested right hemisphere pattern for blue/yellow chromatic opponency by men, and a left hemisphere pattern by women. MATERIALS AND METHODS: The present study measured the accumulation of [18F]fluorodeoxyglucose ([18F]FDG) in mouse brain using small animal positron emission tomography and magnetic resonance imaging (PET/MRI) with statistical parametric mapping (SPM) during light stimulation with blue and yellow filters compared to darkness condition...
2017: PloS One
https://www.readbyqxmd.com/read/28723740/case-report-multiple-systemic-disseminated-tuberculosis-mimicking-lymphoma-on-18f-fdg-pet-ct
#15
Shasha Hou, Jie Shen, Jian Tan
RATIONALE: F-fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has an important role in the diagnosis of various malignancies. However, F-18 FDG can also exhibit intense accumulation in tissues in inflammatory conditions such as active tuberculosis (TB) and sarcoidosis. PATIENT CONCERNS: We report a case of a 52-year-old female with irritable cough. CT showed a lung mass with multiple bilateral lung nodules, and sarcoidosis was suspected...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28721937/-18-f-fluorodeoxyglucose-positron-emission-tomography-is-more-sensitive-than-computed-tomography-in-initial-staging-of-patients-with-an-anaplastic-t-cell-lymphoma-first-presenting-in-the-skin
#16
Caroline Ram-Wolff, Laetitia Vercellino, Pauline Brice, Roberta La Selva, Martine Bagot
BACKGROUND: The role of (18)F-fluorodeoxyglucose-positron emission tomography (FDG-PET) in the evaluation of anaplastic large-cell lymphoma (ALCL) first presenting in the skin is not well established, while computed tomography (CT) is used as a standard procedure. OBJECTIVES: The aim of this study was to evaluate the use of FDG-PET versus CT at initial staging of ALCL first presenting in the skin. MATERIALS & METHODS: Eleven cases of ALCL first presenting in the skin who underwent both FDG-PET and CT were retrospectively analysed...
July 19, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28721605/how-to-provide-gadolinium-free-pet-mr-cancer-staging-of-children-and-young-adults-in-less-than-1%C3%A2-h-the-stanford-approach
#17
Anne M Muehe, Ashok J Theruvath, Lillian Lai, Maryam Aghighi, Andrew Quon, Samantha J Holdsworth, Jia Wang, Sandra Luna-Fineman, Neyssa Marina, Ranjana Advani, Jarrett Rosenberg, Heike E Daldrup-Link
PURPOSE: To provide clinically useful gadolinium-free whole-body cancer staging of children and young adults with integrated positron emission tomography/magnetic resonance (PET/MR) imaging in less than 1 h. PROCEDURES: In this prospective clinical trial, 20 children and young adults (11-30 years old, 6 male, 14 female) with solid tumors underwent 2-deoxy-2-[(18)F]fluoro-D-glucose ([(18)F]FDG) PET/MR on a 3T PET/MR scanner after intravenous injection of ferumoxytol (5 mg Fe/kg) and [(18)F]FDG (2-3 MBq/kg)...
July 18, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28721303/value-of-99m-tc-mdp-spect-ct-and-18-f-fdg-pet-ct-scanning-in-the-evaluation-of-malignantly-transformed-fibrous-dysplasia
#18
Wei-Jun Wei, Zhen-Kui Sun, Chen-Tian Shen, Xin-Yun Zhang, Juan Tang, Hong-Jun Song, Zhong-Ling Qiu, Quan-Yong Luo
Although fibrous dysplasia is not considered a potentially premalignant disorder, malignant transformation occurs. Because of its rarity, radiographic features of malignantly transformed fibrous dysplasia on cross-sectional imaging modalities are less recognized, making diagnosis and differential diagnosis of the disease quite difficult in clinical practice. In this study, we analyzed the clinical characteristics, imaging features, pathology findings and surgery strategies of 19 malignantly transformed fibrous dysplasia...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28720271/it-s-a-question-of-endurance-patients-with-head-and-neck-cancer-experiences-of-18-f-fdg-pet-ct-in-a-fixation-mask
#19
Camilla Andersson, Marta Röing, Ylva Tiblom Ehrsson, Birgitta Johansson
PURPOSE: This study aimed to explore how patients with head and neck cancer experienced undergoing an (18)F-fluoro-deoxy-glucose positrons emissions tomography/computed tomography ((18)F-FDG PET/CT) examination in a fixation mask. METHOD: Interviews were conducted with nine patients with known or suspected head and neck cancer who were scheduled for the examination for the first time. The phenomenological method according to van Manen and his four lifeworld existentials; lived space, lived body, lived time, and lived relation was used to analyse the interviews...
August 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28719446/tophaceous-gout-of-the-lumbar-spine-mimicking-malignancy-on-fdg-pet-ct
#20
Qian Zhao, Aisheng Dong, Yushu Bai, Yang Wang, Changjing Zuo
A 46-year-old man with over a 10-year history of gout complained of progressive bilateral buttock pain with numbness of legs for 4 months. Serum uric acid level was elevated. Lumbar radiographs showed decreased density of the bilateral L4-L5 facet joints. CT showed lytic lesions of the facet joints with hyperdense periarticular lesions. Enhanced MRI showed marked enhancement of these lesions. FDG PET/CT showed avid FDG uptake of the bony and periarticular lesions with SUVmax of 16.8. A decompressive posterior lumbar laminectomy with periarticular lesion resection was performed...
July 17, 2017: Clinical Nuclear Medicine
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