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Osteoporosis in men

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https://www.readbyqxmd.com/read/28332125/osteoarthritis-of-the-hip-joint-in-elderly-patients-is-most-commonly-atrophic-with-low-parameters-of-acetabular-dysplasia-and-possible-involvement-of-osteoporosis
#1
Yasuhiro Ishidou, Kanehiro Matsuyama, Daisuke Sakuma, Takao Setoguchi, Satoshi Nagano, Ichiro Kawamura, Shingo Maeda, Setsuro Komiya
As elderly patients with hip osteoarthritis aged, acetabular dysplasia parameters decreased (Sharp's angle, acetabular roof obliquity angle, and acetabular head index) and the incidence of the atrophic type increased. Vertebral body fracture was more frequent in the atrophic type, suggesting the involvement of osteoporosis at the onset of hip osteoarthritis. INTRODUCTION: Osteoarthritis (OA) is associated with increased bone formation at a local site. However, excessive bone resorption has also been found to occur in the early stages of OA...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28326352/aging-lifestyle-factors-hormones-and-bone-health-in-singaporean-men
#2
Victor Hng Hang Goh, William George Hart
PURPOSE: The present study examined how age, bodyweight, body fat, regular exercise and some endocrine factors are associated with osteoporosis, spine bone mineral density (Sbmd) and femoral neck bone mineral density (Fnbmd) in Singaporean men. METHODS: Body composition and bone scans of lumbar spine at L2-L4 and hip were carried out with duel-energy X-ray absorptiometry (DXA). Anthropometric parameters were measured and demographic data, medical history and exercise schedule were collected via a questionnaire...
December 2016: Bone Reports
https://www.readbyqxmd.com/read/28324103/harmonized-reference-ranges-for-circulating-testosterone-levels-in-men-of-four-cohort-studies-in-the-usa-and-europe
#3
Thomas G Travison, Hubert W Vesper, Eric Orwoll, Frederick Wu, Jean Marc Kaufman, Ying Wang, Bruno Lapauw, Tom Fiers, Alvin M Matsumoto, Shalender Bhasin
Background: Reference ranges for testosterone are essential for making a diagnosis of hypogonadism in men. Objective: To establish harmonized reference ranges for total testosterone in men that can be applied across laboratories by cross-calibrating cohort-specific assays to a reference method and standard. Population: 9054 community-dwelling men in cohort studies in the United States and Europe: Framingham Heart Study; European Male Aging Study; Osteoporotic Fractures in Men Study; Male Sibling Study of Osteoporosis...
January 10, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28316103/identification-of-hip-bmd-loss-and-fracture-risk-markers-through-population-based-serum-proteomics
#4
Carrie M Nielson, Jack Wiedrick, Jian Shen, Jon Jacobs, Erin S Baker, Aaron Baraff, Paul Piehowski, Christine G Lee, Arie Baratt, Vladislav Petyuk, Shannon McWeeney, Jeong Youn Lim, Douglas C Bauer, Nancy E Lane, Peggy M Cawthon, Richard D Smith, Jodi Lapidus, Eric S Orwoll
Serum proteomics analysis may lead to the discovery of novel osteoporosis biomarkers. The Osteoporotic Fractures in Men Study (MrOS) comprises men ≥65 in the US who have had repeated BMD measures and have been followed for incident fracture. High-throughput quantitative proteomic analysis was performed on baseline fasting serum samples from non-Hispanic white men using a multi-dimensional approach coupling liquid chromatography, ion-mobility separation, and mass spectrometry (LC-IMS-MS). We followed the participants for a mean of 4...
March 18, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28314897/transient-osteoporosis-of-the-hip-review-of-the-literature
#5
REVIEW
K Asadipooya, L Graves, L W Greene
Transient osteoporosis of the hip (TOH) is a temporary clinical condition of unknown etiology which usually resolves with conservative therapy though may be complicated by fracture or progression to avascular necrosis (AVN). TOH may be slightly more prevalent in men but when it occurs in women, it is most often seen in the latter part of pregnancy. Though fracture is a rare complication of TOH when it occurs, it is most often associated with TOH occurring in pregnancy. Magnetic resonance imaging (MRI) is the best method to diagnosis TOH...
March 17, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28304090/osteoporosis-treatment-efficacy-for-men-a-systematic-review-and-meta-analysis
#6
Smita Nayak, Susan L Greenspan
OBJECTIVES: To evaluate the efficacy of treatment options to reduce osteoporotic fracture risk in men. DESIGN: Systematic review and meta-analysis. SETTING: Randomized clinical trials that evaluated the efficacy of a treatment for osteoporosis or low bone mineral density for adult men and reported fracture outcomes. PARTICIPANTS: Men. MEASUREMENTS: PubMed, Embase, and the Cochrane Library databases were searched for relevant studies...
March 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28303402/association-between-metabolic-syndrome-and-bone-mineral-density-in-a-taiwanese-elderly-population
#7
Song-Seng Loke, Hsueh-Wen Chang, Wen-Cheng Li
Previous studies have demonstrated uncertainty regarding the effect of metabolic syndrome (MetS) on bone. In the present work, we investigated the association between MetS, its components, and decreased bone mineral density (BMD) in a cross-sectional study of patients who underwent BMD measurement by dual-energy X-ray absorptiometry during a health examination. Decreased BMD was defined as either osteopenia or osteoporosis. MetS components and body mass index (BMI) were compared between individuals with normal and decreased BMD, and simple and multivariate logistic regression analyses were used to evaluate the association between the variables and decreased BMD in women and men...
March 16, 2017: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/28303396/the-incidence-of-hip-fracture-in-shiraz-iran-a-promising-rate-comparing-to-previous-studies
#8
N Maharlouei, S Atefi, H Namazi, S Kazemifar, M Soveid, H R Shahraki, Z Farahmand, M Khodayari, P Arab, F Forouzan, N Allamehzadeh, S Fazilat, S Khademolhosseini, F Nafari, K B Lankarani
We evaluate the incidence of hip fracture in 50 years old or above in southwest of Iran. Age-adjusted incidence rates of hip fracture, standardized to the 2000 US white population, were 79.55 per 10(5) in total and 66.51 and 92.37 per 10(5) in male and female, respectively. INTRODUCTION: Osteoporosis-related hip fracture is associated with considerable morbidity, mortality, and costs in older people. The aim of this study was to evaluate the incidence rate of hip fracture in the capital of Fars Province, southern Iran...
March 16, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28293453/an-overview-and-management-of-osteoporosis
#9
REVIEW
Tümay Sözen, Lale Özışık, Nursel Çalık Başaran
Osteoporosis -related to various factors including menopause and aging- is the most common chronic metabolic bone disease, which is characterized by increased bone fragility. Although it is seen in all age groups, gender, and races, it is more common in Caucasians (white race), older people, and women. With an aging population and longer life span, osteoporosis is increasingly becoming a global epidemic. Currently, it has been estimated that more than 200 million people are suffering from osteoporosis. According to recent statistics from the International Osteoporosis Foundation, worldwide, 1 in 3 women over the age of 50 years and 1 in 5 men will experience osteoporotic fractures in their lifetime...
March 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28290906/-bone-metabolism-and-mineral-density-in-chronic-heart-failure
#10
V N Larina, T N Raspopova
PURPOSE: to assess the state of bone metabolism and mineral density in outpatients with chronic heart failure (CHF). MATERIAL AND METHODS: We examined 70 outpatients (30 men, 40 women, aged 56-88 years) with CHF and 40 outpatients without CHF (10 men, 30 women, aged 57-88 years). Examination included laboratory assessment, echocardiography, study of bone mineral density (BMD) in the lumbar spine and femoral neck using dual-energy X-ray absorptiometry. RESULTS: Osteoporosis was recorded in 61...
July 2016: Kardiologiia
https://www.readbyqxmd.com/read/28288973/bone-mineral-density-and-risk-of-heart-failure-in-older-adults-the-cardiovascular-health-study
#11
Raymond B Fohtung, David L Brown, William J H Koh, Traci M Bartz, Laura D Carbone, Roberto Civitelli, Phyllis K Stein, Paulo H M Chaves, Bryan R Kestenbaum, Jorge R Kizer
BACKGROUND: Despite increasing evidence of a common link between bone and heart health, the relationship between bone mineral density (BMD) and heart failure (HF) risk remains insufficiently studied. METHODS AND RESULTS: We investigated whether BMD measured by dual-energy x-ray absorptiometry was associated with incident HF in an older cohort. Cox models were stratified by sex and interactions of BMD with race assessed. BMD was examined at the total hip and femoral neck separately, both continuously and by World Health Organization categories...
March 13, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28264244/demineralized-bone-matrix-dbm-as-a-bone-void-filler-in-lumbar-interbody-fusion-a-prospective-pilot-study-of-simultaneous-dbm-and-autologous-bone-grafts
#12
Bum-Joon Kim, Se-Hoon Kim, Haebin Lee, Seung-Hwan Lee, Won-Hyung Kim, Sung-Won Jin
OBJECTIVE: Solid bone fusion is an essential process in spinal stabilization surgery. Recently, as several minimally invasive spinal surgeries have developed, a need of artificial bone substitutes such as demineralized bone matrix (DBM), has arisen. We investigated the in vivo bone growth rate of DBM as a bone void filler compared to a local autologous bone grafts. METHODS: From April 2014 to August 2015, 20 patients with a one or two-level spinal stenosis were included...
March 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28263366/ageism-in-studies-on-the-management-of-osteoporosis
#13
Caoimhe McGarvey, Tara Coughlan, Desmond O'Neill
OBJECTIVES: To review the literature to assess whether the fact that osteoporosis is chiefly considered a disease of the older population was reflected in research in the area of the management of osteoporosis and to determine the extent of ageism in studies on the management of osteoporosis. DESIGN: Review. SETTING: All randomized control trials on the management of osteoporosis entered in the Cochrane Library Database that reported mean age were included...
March 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28261864/total-and-visceral-adiposity-are-associated-with-prevalent-vertebral-fracture-in-women-but-not-men-at-age-62-years-the-newcastle-thousand-families-study
#14
Karen Hind, Mark Pearce, Fraser Birrell
Low body weight is an established risk factor for osteoporosis and fracture, but the skeletal risks of higher adiposity are unclear and appear sex-specific and site-dependent. The aim of this study was to investigate associations of total fat mass (TFM), visceral adipose tissue (VAT), and C-reactive protein (CRP) with bone mineral density (BMD) and prevalent vertebral fracture (VF) in men and women aged 62 years. A total of 352 men and women aged 62.5 ± 0.5 years from the Newcastle Thousand Families Study cohort received dual-energy X-ray absorptiometry (DXA) evaluations of femoral neck and lumbar spine BMD, of the lateral spine for vertebral fracture assessment, and of the whole body for TFM and VAT (GE Lunar CoreScan, Madison, WI, USA)...
March 6, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28258372/fracture-burden-what-two-and-a-half-decades-of-dubbo-osteoporosis-epidemiology-study-data-reveal-about-clinical-outcomes-of-osteoporosis
#15
REVIEW
Jacqueline R Center
PURPOSE OF THE REVIEW: This review aims to highlight important clinical findings from the over 25 year-long Dubbo Osteoporosis Epidemiology Study particularly focusing on outcomes post fracture. RECENT FINDINGS: Every low trauma fracture in the elderly is associated with an increased risk of a subsequent fracture, with a higher risk in men than women. All major or proximal fractures and even minor fractures in the very elderly or minor fractures that are then followed by re-fracture are associated with premature mortality, greatest in the first 5 years post fracture...
March 3, 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28256011/population-wide-impact-of-non-hip-non-vertebral-fractures-on-mortality
#16
Thach Tran, Dana Bliuc, Tineke van Geel, Jonathan D Adachi, Claudie Berger, Joop van den Bergh, John A Eisman, Piet Geusens, David Goltzman, David A Hanley, Robert G Josse, Stephanie M Kaiser, Christopher S Kovacs, Lisa Langsetmo, Jerilynn C Prior, Tuan V Nguyen, Jacqueline R Center
Data on long-term consequences of non-hip non-vertebral (NHNV) fractures, accounting for approximately two thirds of all fragility fractures are scanty. Our study aimed to quantify the population-wide impact of NHNV fractures on mortality. The national population-based prospective cohort study (Canadian Multicentre Osteoporosis Study) included 5526 community dwelling women and 2163 men aged 50 years or older followed up from July 1995 to September 2013. Population impact number was used to quantify the average number of people for whom one death would be attributable to fracture and case impact number to quantify the number of deaths out of which one would be attributable to a fracture...
March 3, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28255281/clinical-and-genetic-advances-in-paget-s-disease-of-bone-a-review
#17
REVIEW
N Alonso, I Calero-Paniagua, J Del Pino-Montes
Paget's disease of bone (PDB) is the second most common metabolic bone disorder, after osteoporosis. It is characterised by focal areas of increased and disorganised bone turnover, coupled with increased bone formation. This disease usually appears in the late stages of life, being slightly more frequent in men than in women. It has been reported worldwide, but primarily affects individuals of British descent. Majority of PDB patients are asymptomatic, but clinical manifestations include pain, bone deformity and complications, like pathological fractures and deafness...
2017: Clinical Reviews in Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/28253947/-periprosthetic-femoral-fractures-after-total-hip-replacement-our-results-and-treatment-complications
#18
T Pavelka, M Salášek, D Weisová
PURPOSE OF THE STUDY The study consists of a retroactive evaluation of results of surgical treatment in patients with periprosthetic femoral fracture after total hip replacement and a comparison with results reported in the literature. MATERIAL AND METHODS In the period from 2003 to 2013, a total of 83 patients with periprosthetic femoral fracture after total hip replacement were treated at our clinic, namely 69 women and 14 men. The mean age in the cohort was 74 years (range 47-87). The Vancouver classification was used to grade the fractures...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28248870/association-factor-analysis-between-osteoporosis-with-cerebral-artery-disease-the-strobe-study
#19
Eun-Sun Jin, Je Hoon Jeong, Bora Lee, Soo Bin Im
The purpose of this study was to determine the clinical association factors between osteoporosis and cerebral artery disease in Korean population. Two hundred nineteen postmenopausal women and men undergoing cerebral computed tomography angiography were enrolled in this study to evaluate the cerebral artery disease by cross-sectional study. Cerebral artery disease was diagnosed if there was narrowing of 50% higher diameter in one or more cerebral vessel artery or presence of vascular calcification. History of osteoporotic fracture was assessed using medical record, and radiographic data such as simple radiography, MRI, and bone scan...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28236128/socioeconomic-status-and-bone-mineral-density-in-adults-by-race-ethnicity-and-gender-the-louisiana-osteoporosis-study
#20
Y Du, L-J Zhao, Q Xu, K-H Wu, H-W Deng
Low bone mineral density (BMD) and osteoporosis have become a public health problem. We found that non-Hispanic white, black, and Asian adults with extremely low education and personal income are more likely to have lower BMD. This relationship is gender-specific. These findings are valuable to guide bone health interventions. INTRODUCTION: The evidence is limited regarding the relationship between socioeconomic status (SES) and bone mineral density (BMD) for minority populations in the USA, as well as the relationship between SES and BMD for men...
February 24, 2017: Osteoporosis International
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