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Osteoporosis in men

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https://www.readbyqxmd.com/read/28551925/-clinical-characteristics-of-male-patients-with-osteoporosis-referred-to-the-endocrine-clinic-of-a-tertiary-hospital
#1
Gloria Tsvetov, Ilana Shraga-Slutzky, Dania Hirsch, Hiba Masri, Tzippy Shohat, Alexander Gorshtein, Ilan Shimon
INTRODUCTION: Osteoporosis in men is underdiagnosed and undertreated. The prevalence of male osteoporosis increases with age and it becomes a significant public health burden. Currently, there are a few clinical studies on male osteoporosis with limited knowledge of effective therapeutic options. AIMS: Our study aimed to characterize men with osteoporosis in a referral metabolic clinic in Rabin Medical Center at the Beilinson Campus. METHODS: In this study we retrospectively analyzed the medical records of 270 consecutive male patients with osteoporosis diagnosed and treated in our clinic during 2013...
April 2017: Harefuah
https://www.readbyqxmd.com/read/28549839/vitamin-b12-deficiency-might-be-related-to-sarcopenia-in-older-adults
#2
Esra Ates Bulut, Pinar Soysal, Ali Ekrem Aydin, Ozge Dokuzlar, Suleyman Emre Kocyigit, Ahmet Turan Isik
Sarcopenia and dynapenia are related to repeated falls, mobility restriction, depression, frailty, increased mortality and morbidity. The aim of this study is to evaluate the relationship between vitamin B12 deficiency and sarcopenia in older adults. 403 patients, who attended to outpatient clinic and underwent comprehensive geriatric assessment, were included study. All cases' skeletal muscle mass (SMM), walking speed and hand grip strength were recorded by bioimpedance, 4meter walking test and hand dynamometer respectively...
May 23, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28549357/-hip-osteosynthesis-with-im-nail-lateral-decubitus-without-fracture-table
#3
V H Aguirre-Rodríguez, G Inzunza-Enríquez, O Bibiano-Escalante, F J Martínez-Ruiz, F S Valero-González
BACKGROUND: Hip fractures have increased in the last decades, mainly in elderly patients with osteoporosis. The incidence becomes in some countries up to 250 thousand new cases per year, generating millions for health systems costs, so it should be considered a public health problem. They are treated in supine position, with a fracture table, through a lateral approach. However, it is important to know that there are other techniques, which can dispense a table of fractures and in a different position...
November 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28543687/effect-of-a-single-intravenous-zoledronic-acid-administration-on-biomarkers-of-acute-kidney-injury-aki-in-patients-with-osteoporosis-a-pilot-study
#4
C Cipriani, J Pepe, C Clementelli, R Manai, L Colangelo, V Fassino, L Nieddu, S Minisola
AIMS: The pilot study was designed to evaluate the early effect of intravenous (iv) zoledronic acid (ZA) on renal function. METHODS: Five mg iv ZA was administered to 23 patients with osteoporosis (17 women and 6 men, mean age 73±7 SD years). Urinary NGAL, KIM-1, and MCP-1, plasma (p) MCP-1 and serum (s) IL-18, serum calcium (sCa), Creatinine clearance (CrCl), parathyroid hormone (PTH), plasma C-terminal FGF23 (pFGF23), serum (s) Klotho, calcium excretion (CaEx) and renal threshold phosphate concentration/GFR (TmPO4/GFR) were assessed at baseline, 24 hours (h) and day (d) 30 after administration...
May 25, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28536889/the-phenotype-of-patients-with-a-recent-fracture-a-literature-survey-of-the-fracture-liaison-service
#5
REVIEW
Lisanne Vranken, Caroline E Wyers, Joop P W van den Bergh, Piet P M M Geusens
The aetiology of fractures in patients aged 50 years and older is multifactorial, and includes bone- and fall-related risks. The Fracture Liaison Service (FLS) is recommended to identify patients with a recent fracture and to evaluate their subsequent fracture risk, in order to take measures to decrease the risk of subsequent fractures in patients with a high risk phenotype. A literature survey was conducted to describe components of the bone- and fall-related phenotype of patients attending the FLS. Components of the patient phenotype at the FLS have been reported in 33 studies...
May 24, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28528985/atrial-fibrillation-and-risk-of-hip-fracture-a-population-based-analysis-of-113-600-individuals
#6
Christopher X Wong, Siang Wei Gan, Sarah W Lee, Celine Gallagher, Ned J Kinnear, Dennis H Lau, Rajiv Mahajan, Kurt C Roberts-Thomson, Prashanthan Sanders
BACKGROUND: A number of cardiovascular diseases have been linked with bone health and an increased risk of osteoporotic fracture. Whether atrial fibrillation (AF) is associated with subsequent fracture risk is not known. METHODS: Administrative, clinical and hospitalisation information were linked over a 14-year period. From this longitudinal, population-based dataset of 113,600 individuals, time-dependent exposures using multivariate Cox proportional hazards regression models were employed to determine incidence rates and hazard ratios (HR) for hip fracture according to a history of AF...
May 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28524056/dermatitis-herpetiformis-and-bone-mineral-density-analysis-of-a-french-cohort-of-53-patients
#7
Coralie Lheure, Saskia Ingen-Housz-Oro, Sandra Guignard, Rachida Inaoui, Brigitte Jolivet, Xavier Chevalier, Pierre Wolkenstein, Bruno Fautrel, Oliver Chosidow
The characteristics of patients with dermatitis herpetiformis (DH) in France is poorly documented. Furthermore, the risk of fractures and bone mineral density (BMD) in DH remain under-described, and recommendations for systematic screening for osteoporosis in DH are lacking. To describe the characteristics of DH in a large French cohort and evaluate the association between BMD and features of osteoporosis. Patients were recruited from the French Association of Gluten Intolerants (AFDIAG) and a single university dermatology department...
May 19, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28521374/phytochemistry-and-pharmacology-of-ferula-hermonis-boiss-a-review
#8
Zohreh Sattar, Mehrdad Iranshahi
Ferula hermonis, a well-known species of the genus Ferula found in Lebanon and Syria, has a brilliant history in traditional medicine as it has been used for the treatment of erectile dysfunction in men and menopausal disturbances in women. Thanks to modern pharmacological and clinical investigations, F. hermonis is a valuable medicinal and condimental plant that may be used for the treatment of impotence and diabetes, the prevention of osteoporosis, and possesses anti-microbial and anti-inflammatory properties...
May 18, 2017: Drug Research
https://www.readbyqxmd.com/read/28501236/women-s-health-polycystic-ovarian-syndrome-menopause-and-osteoporosis
#9
REVIEW
Melinda Ring
Surveys consistently show that a significantly higher percentage of women with chronic medical conditions report use of complementary and integrative medicine (CIM) approaches compared with men. A total of 54.5% of women report use of at least one CIM approach specifically for obstetric or gynecologic problems. However, primary care providers remain an underutilized resource by patients for guidance in the safe and appropriate use of integrative therapies. This article provides a practical overview of the most appropriate integrative therapies to consider in the management of commonly seen women's health conditions: polycystic ovarian syndrome, menopause, and osteoporosis...
June 2017: Primary Care
https://www.readbyqxmd.com/read/28492856/treatment-of-low-bone-density-or-osteoporosis-to-prevent-fractures-in-men-and-women-a-clinical-practice-guideline-update-from-the-american-college-of-physicians
#10
Amir Qaseem, Mary Ann Forciea, Robert M McLean, Thomas D Denberg
Description: This guideline updates the 2008 American College of Physicians (ACP) recommendations on treatment of low bone density and osteoporosis to prevent fractures in men and women. This guideline is endorsed by the American Academy of Family Physicians. Methods: The ACP Clinical Guidelines Committee based these recommendations on a systematic review of randomized controlled trials; systematic reviews; large observational studies (for adverse events); and case reports (for rare events) that were published between 2 January 2005 and 3 June 2011...
May 9, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28488465/surgical-management-of-lower-limb-fractures-in-patients-with-spinal-cord-injury-less-associated-with-complications-than-non-operative-management-a-retrospective-series-of-cases
#11
Alban Fouasson-Chailloux, Raphael Gross, Marc Dauty, Guillaume Gadbled, Sophie Touchais, Marc Le Fort, Brigitte Perrouin-Verbe
OBJECTIVES: To evaluate the difference in terms of overall complications between surgical and non-surgical management of lower limb fractures in patients with chronic spinal cord injury (SCI). DESIGN: A 13-year retrospective study including patients with chronic spinal cord lesion admitted for sublesional lower limb fractures. SETTING: University hospital SCI reference departments (Rehabilitation department and orthopedic department). PARTICIPANTS: Forty patients with SCI were included, 24 men and 16 women...
May 10, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28480789/bone-mineral-density-at-distal-forearm-in-men-over-40-years-of-age-in-mae-chaem-district-chiang-mai-province-thailand-a-pilot-study
#12
Montree Tungjai, Siriprapa Kaewjaeng, Chayanit Jumpee, Sompong Sriburee, Pongsiri Hongsriti, Monruedee Tapanya, Utumma Maghanemi, Kwanchai Ratanasthien, Suchart Kothan
OBJECTIVE: To study the prevalence of bone mineral density (BMD) and osteoporosis in the distal forearm among Thai men over 40 years of age in Mae Chaem District, Chiang Mai Province, Thailand. METHODS: The subjects in this study were 194 Thai men, aged between 40 and 87 years who resided in Mae Chaem District, Chiang Mai Province, Thailand. Self-administered questionnaires were used for receiving the demographic characteristics information. BMD was measured by peripheral dual energy X-ray absorptiometry at the nondominant distal forearm in all men...
May 8, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28474432/associations-of-muscle-force-power-cross-sectional-muscle-area-and-bone-geometry-in-older-uk-men
#13
Ayse Zengin, Stephen R Pye, Michael J Cook, Judith E Adams, Rainer Rawer, Frederick C W Wu, Terence W O'Neill, Kate A Ward
BACKGROUND: Ageing is associated with sarcopenia, osteoporosis, and increased fall risk, all of which contribute to increased fracture risk. Mechanically, bone strength adapts in response to forces created by muscle contractions. Adaptations can be through changes in bone size, geometry, and bending strength. Muscle mass is often used as a surrogate for muscle force; however, force can be increased without changes in muscle mass. Increased fall risk with ageing has been associated with a decline in muscle power-which is a measure of mobility...
May 4, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28473075/acr-appropriateness-criteria-%C3%A2-osteoporosis%C3%A2-and%C3%A2-bone-mineral-density
#14
Robert J Ward, Catherine C Roberts, Jenny T Bencardino, Erin Arnold, Steven J Baccei, R Carter Cassidy, Eric Y Chang, Michael G Fox, Bennett S Greenspan, Soterios Gyftopoulos, Mary G Hochman, Douglas N Mintz, Joel S Newman, Charles Reitman, Zehava S Rosenberg, Nehal A Shah, Kirstin M Small, Barbara N Weissman
Osteoporosis is a considerable public health risk, with 50% of women and 20% of men >50 years of age experiencing fracture, with mortality rates of 20% within the first year. Dual x-ray absorptiometry (DXA) is the primary diagnostic modality by which to screen women >65 years of age and men >70 years of age for osteoporosis. In postmenopausal women <65 years of age with additional risk factors for fracture, DXA is recommended. Some patients with bone mineral density above the threshold for treatment may qualify for treatment on the basis of vertebral body fractures detected through a vertebral fracture assessment scan, a lateral spine equivalent generated from a commercial DXA machine...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28459415/frax-based-estimates-of-10-year-probability-of-hip-and-major-osteoporotic-fracture-among-adults-aged-40-and-over-united-states-2013-and-2014
#15
Anne C Looker, Neda Sarafrazi Isfahani, Bo Fan, John A Shepherd
BACKGROUND: The FRAX algorithm estimates the 10-year probability of hip and major osteoporotic (clinical spine, forearm, hip, or humerus) fracture for adults aged 40 and over. An expert panel developed criteria to define elevated FRAX probabilities for U.S. adults aged 50 and over. This report uses FRAX estimates from the National Health and Nutrition Examination Survey 2013-2014 to describe the hip and major osteoporotic fracture probability distribution (for adults aged 40 and over) and prevalence of elevated probabilities (for adults aged 50 and over) in the United States...
March 2017: National Health Statistics Reports
https://www.readbyqxmd.com/read/28455749/comparison-of-two-automated-assays-of-btm-ctx-and-p1np-and-reference-intervals-in-a-danish-population
#16
N R Jørgensen, L T Møllehave, Y B L Hansen, N Quardon, L Lylloff, A Linneberg
Bone turnover markers are used for monitoring osteoporosis treatment. Therefore, we evaluated the agreement between different assays for CTX and PINP and established reference intervals in a cohort of 2300 individuals. We found poor agreement between assays and different reference intervals. This highlights the importance of harmonization of the assays. INTRODUCTION: Two reference markers for bone turnover have been proposed: CTX bone resorption and P1NP for bone formation. The purpose of the current study was to establish reference intervals for the two markers in a Danish cohort and to determine the agreement on the two platforms...
April 28, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28453635/peak-bone-mass-and-bone-microarchitecture-in-adults-born-with-low-birth-weight-preterm-or-at-term-a-cohort-study
#17
Chandima Balasuriya, Kari Anne I Evensen, Mats P Mosti, Ann-Mari Brubakk, Geir W Jacobsen, Marit S Indredavik, Berit Schei, Astrid Kamilla Stunes, Unni Syversen
Context and objectives: Peak bone mass (PBM) is regarded as the most important determinant of osteoporosis. Growing evidence suggests a role of intrauterine programming in skeletal development. We examined PBM and trabecular bone score (TBS) in adults born preterm with very low birth weight (VLBW) or small for gestational age (SGA) at term compared with term-born controls. Design, setting, participants and outcomes: This follow-up cohort study included 186 men and women (25-28 years); 52 preterm VLBW (≤ 1500g), 59 term-born SGA (< 10th percentile), and 75 controls (>10th percentile)...
April 27, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28453310/vasomotor-symptoms-in-menopause-a-biomarker-of-cardiovascular-disease-risk-and-other-chronic-diseases
#18
N Biglia, A Cagnacci, M Gambacciani, S Lello, S Maffei, R E Nappi
Menopausal disorders may include shorter-term symptoms, such as hot flushes and night sweats (vasomotor symptoms, VMS) and longer-term chronic conditions such as cardiovascular disease (CVD), osteoporosis, and cognitive impairment. Initially, no clear link between the shorter-term symptoms and longer-term chronic conditions was evident and these disorders seemed to occur independently from each other. However, there is a growing body of evidence demonstrating that VMS may be a biomarker for chronic disease...
April 28, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28448327/community-osteoporosis-screening-services-for-the-prevention-of-osteoporotic-fractures-in-population-health-a-literature-review
#19
Vu H Nguyen
AIM: To determine the implications of the reviewed literature in population health improvement. METHOD: A review of the literature was conducted with the search of four databases: PubMed, PsycINFO, ERIC, and Google Scholar. Search terms entered into these databases were 'osteoporosis community'. After a thorough review of all search results, 11 studies were found to be community osteoporosis screening services, and descriptions of each study's participants and location, details and descriptions of each study's community osteoporosis screening service, and effectiveness on outcome measure(s) for each study's objective were reviewed and examined to determine their implications on population health...
April 26, 2017: International Journal of Evidence-based Healthcare
https://www.readbyqxmd.com/read/28442297/vertebral-and-femoral-bone-mineral-density-and-bone-strength-in-prostate-cancer-patients-assessed-in-phantomless-pet-ct-examinations
#20
Benedikt J Schwaiger, David L Kopperdahl, Lorenzo Nardo, Luca Facchetti, Alexandra S Gersing, Jan Neumann, Kwang J Lee, Tony M Keaveny, Thomas M Link
PURPOSE: Bone fracture risk assessed ancillary to positron emission tomography with computed tomography co-registration (PET/CT) could provide substantial clinical value to oncology patients with elevated fracture risk without introducing additional radiation dose. The purpose of our study was to investigate the feasibility of obtaining valid measurements of bone mineral density (BMD) and finite element analysis-derived bone strength of the hip and spine using PET/CT examinations of prostate cancer patients by comparing against values obtained using routine multidetector-row computed tomography (MDCT) scans-as validated in previous studies-as a reference standard...
April 24, 2017: Bone
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