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Osteoporosis in men

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https://www.readbyqxmd.com/read/28631583/dietary-magnesium-intake-and-fracture-risk-data-from-a-large-prospective-study
#1
Nicola Veronese, Brendon Stubbs, Marco Solmi, Marianna Noale, Alberto Vaona, Jacopo Demurtas, Stefania Maggi
Research considering the relationship between dietary Mg and osteoporosis as well as fractures are sparse and conflicting. We therefore aimed to investigate Mg intake and the onset of fractures in a large cohort of American men and women involved in the Osteoarthritis Initiative over a follow-up period of 8 years. Dietary Mg intake (including that derived from supplementation) was evaluated through a FFQ at baseline and categorised using sex-specific quintiles (Q); osteoporotic fractures were evaluated through self-reported history...
June 20, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28627197/dietary-antioxidant-quality-score-daqs-is-associated-with-bone-mass-assessed-by-calcaneal-quantitative-ultrasound-in-young-women
#2
María Correa Rodríguez, Jacqueline Schmidt-RioValle, Blanca Rueda-Medina
INTRODUCTION: Evidence suggests that intake of antioxidants could positively influence bone mass by preventing bone metabolism against oxidative stress. OBJECTIVE: We aimed to investigate the possible influence of single antioxidant intakes and dietary antioxidant quality score (DAQs) on calcaneal quantitative ultrasound (QUS) in a population of young adults. METHODS: A total of 605 young Spanish adults participated in this study (median age 20...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28626757/actn3-gene-and-susceptibility-to-sarcopenia-and-osteoporotic-status-in-older-korean-adults
#3
Jinkyung Cho, Inhwan Lee, Hyunsik Kang
BACKGROUND: Little information is available about molecular markers for sarcopenia and osteoporosis in Asian populations. OBJECTIVE: This study investigated the association of the ACTN3 polymorphism with sarcopenia and osteoporotic status in older Korean adults. METHODS: Older Korean 62 men and 270 women (mean age 73.7 ± 6.6 years) participated in this study. Body mass index, percent body fatness, appendicular skeletal muscle mass, and bone mineral density of the lumbar spine, femur, and total body were analyzed with dual-energy X-ray absorptiometry...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28612552/-obesity-and-osteoporosis-in-men-aged-above-50
#4
Ken Qin, Min He, Xiao-Tao Cao, Han-Wei Yang, Ying Yang, You-Juan Wang, Chuan Yu, Zhen-Mei An, She-Yu Li
OBJECTIVES: To investigate the association between obesity and osteoporosis in men aged above 50 in Chengdu. METHODS: Male participants aged above 50 were recruited from those who visited West China Hospital of Sichuan University for health examinations. Bone mineral density was measured by MetriScan Bone Densitometry. The participants were divided into three groups according to T values: normal, osteopenia and osteoporosis. RESULTS: About 5...
January 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28611110/the-liftmor-m-lifting-intervention-for-training-muscle-and-osteoporosis-rehabilitation-for-men-trial-protocol-for-a-semirandomised-controlled-trial-of-supervised-targeted-exercise-to-reduce-risk-of-osteoporotic-fracture-in-older-men-with-low-bone-mass
#5
Amy T Harding, Benjamin K Weeks, Steven L Watson, Belinda R Beck
INTRODUCTION: The primary aim of the proposed study is to examine the efficacy of an 8-month supervised, high-intensity progressive resistance training and impact loading programme in comparison with a supervised machine-based isometric exercise training programme using the bioDensity system in older men with low bone mass. We will also determine the safety and acceptability of each exercise training mode. Intervention group responses will be compared with those of a self-selected, non-randomised control sample of sex-matched and age-matched men who will follow their usual lifestyle activities for 8 months...
June 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28607522/agreement-between-fragility-fracture-risk-assessment-algorithms-as-applied-to-adults-with-chronic-spinal-cord-injury
#6
T Cervinka, C L Lynch, L Giangregorio, J D Adachi, A Papaioannou, L Thabane, B C Craven
STUDY DESIGN: Cross-sectional. OBJECTIVES: The objective of the study was to determine and report agreement in fracture risk stratification of adults with spinal cord injury (SCI) using (1) Canadian Association of Radiologists and Osteoporosis Canada (CAROC) and Canadian Fracture Risk Assessment (FRAX) tools with and without areal bone mineral density (aBMD) and (2) SCI-specific fracture thresholds. SETTING: Tertiary rehabilitation center, Ontario, Canada...
June 13, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28606219/dietary-calcium-intake-and-rate-of-bone-loss-in-men
#7
Sarah M Bristow, Gregory D Gamble, Anne M Horne, Ian R Reid
A high Ca intake has been recommended for osteoporosis prevention; however, little research has examined the relationship between dietary Ca and bone health in men. We examined associations between dietary Ca intake, bone mineral density (BMD) and change in BMD at the total body, hip and spine over 2 years in a cohort of men (mean age 57 years, BMI 26 kg/m2) from a trial. Data from the total cohort (n 323) were used in the analysis of Ca intake and BMD at baseline, and data from the placebo group (n 99) were used in the longitudinal analysis of Ca intake and change in BMD...
June 13, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28598810/the-prevention-of-fragility-fractures-in-patients-with-non-metastatic-prostate-cancer-a-position-statement-by-the-international-osteoporosis-foundation
#8
REVIEW
Luisella Cianferotti, Francesco Bertoldo, Marco Carini, John A Kanis, Alberto Lapini, Nicola Longo, Giuseppe Martorana, Vincenzo Mirone, Jean-Yves Reginster, Rene Rizzoli, Maria Luisa Brandi
Androgen deprivation therapy is commonly employed for the treatment of non-metastatic prostate cancer as primary or adjuvant treatment. The skeleton is greatly compromised in men with prostate cancer during androgen deprivation therapy because of the lack of androgens and estrogens, which are trophic factors for bone. Men receiving androgen deprivation therapy sustain variable degrees of bone loss with an increased risk of fragility fractures. Several bone antiresorptive agents have been tested in randomized controlled trials in these patients...
May 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28591464/risk-of-low-bone-mineral-density-in-testicular-germ-cell-cancer-survivors-association-with-hypogonadism-and-treatment-modality
#9
S Isaksson, K Bogefors, K Åkesson, L Egund, J Bobjer, I Leijonhufvud, A Giwercman
The cure rate of testicular cancer exceeds 95%, but testicular cancer survivors (TCS) are at increased risk of hypogonadism (HG). It has been suggested that TCS have reduced bone mineral density (BMD), but it is unclear whether this is related to HG or a direct effect of cancer therapy. The aim of this study was to evaluate whether TCS have decreased BMD, and if BMD is related to HG and/or the cancer treatment given. We investigated 91 TCS (mean age at diagnosis: 31 years; mean 9.3 years follow-up) and equal number of age matched controls (mean age at inclusion 40...
June 7, 2017: Andrology
https://www.readbyqxmd.com/read/28589453/bone-seeking-agents-for-the-treatment-of-bone-disorders
#10
REVIEW
Jacqueline Cawthray, Ellen Wasan, Kishor Wasan
The targeting and delivery of therapeutic and diagnostic agents to bone tissue presents both a challenge and opportunity. Osteoporosis, Paget's disease, cancer, and bone metastases are all skeletal diseases whose treatment would benefit from new targeted therapeutic strategies. Osteoporosis, in particular, is a very prevalent disease, affecting over one in three women and one in five men in Canada alone with the cost to the healthcare system estimated at over $2.3 billion in 2010. Bone tissue is often considered a rigid structure when in reality there is a process of continuous remodeling that takes place via complex endocrine-regulated cell signaling pathways in addition to the signaling pathways unique to bone tissue...
June 6, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28580402/bone-microstructure-in-men-assessed-by-hr-pqct-associations-with-risk-factors-and-differences-between-men-with-normal-low-and-osteoporosis-range-areal-bmd
#11
Narihiro Okazaki, Andrew J Burghardt, Ko Chiba, Anne L Schafer, Sharmila Majumdar
PURPOSE: The primary objective of this study was to analyze the relationships between bone microstructure and strength, and male osteoporosis risk factors including age, body mass index, serum 25-hydroxyvitamin D level, and testosterone level. A secondary objective was to compare microstructural and strength parameters between men with normal, low, and osteoporosis-range areal bone mineral density (aBMD). METHODS: Seventy-eight healthy male volunteers (mean age 62...
December 2016: Bone Reports
https://www.readbyqxmd.com/read/28578992/the-impact-of-fragility-fracture-and-approaches-to-osteoporosis-risk-assessment-worldwide
#12
Elizabeth M Curtis, Rebecca J Moon, Nicholas C Harvey, Cyrus Cooper
Osteoporosis constitutes a major public health problem, through its association with age-related fractures, particularly of the hip, vertebrae, distal forearm and humerus. Substantial geographic variation has been noted in the incidence of osteoporotic fractures worldwide, with Western populations (North America, Europe and Oceania), reporting increases in hip fracture throughout the second half of the 20th century, with a stabilisation or decline in the last two decades. In developing populations however, particularly in Asia, the rates of osteoporotic fracture appears to be increasing...
April 26, 2017: International Journal of Orthopaedic and Trauma Nursing
https://www.readbyqxmd.com/read/28578545/modifiable-lifestyle-factors-associated-with-osteoporosis-in-korean-men-a-case-control-study
#13
Kye-Yeung Park, Hwan-Sik Hwang, Hoon-Ki Park
The prevention, education, and treatment of osteoporosis are all recognized as important components in men as well as women. This study revealed that the lifestyle factors associated with male osteoporosis included being underweight and being a current smoker. Being overweight or obese and having a regular exercise habit were negatively associated with male osteoporosis. PURPOSE: Osteoporosis is a significant health problem in Korea and worldwide. Although osteoporosis is less prevalent in males than in females, the fracture-related mortality rate is higher in males than in females...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28574962/an-increased-rate-of-fracture-occurs-a-decade-earlier-in-hiv-compared-with-hiv-men
#14
Anda Gonciulea, Ruibin Wang, Keri N Althoff, Frank J Palella, Jordan Lake, Lawrence A Kingsley, Todd T Brown
OBJECTIVES: To determine the incidence of fracture among aging HIV-infected (HIV+) and uninfected men (HIV-). To evaluate factors independently associated with fracture risk. DESIGN: Prospective, multicenter cohort study of men with or at risk for HIV. METHODS: Outcome measures: all fractures (excluding skull, face and digits) and fragility fractures (vertebral column, femur, wrist and humerus) were collected semiannually in 1221 HIV+ and 1408 HIV- men aged at least 40...
June 19, 2017: AIDS
https://www.readbyqxmd.com/read/28570093/predicting-future-hip-fractures-on-routine-abdominal-ct-using-opportunistic-osteoporosis-screening-measures-a-matched-case-control-study
#15
Scott J Lee, Paul A Anderson, Perry J Pickhardt
OBJECTIVE: Hip fracture is a major consequence of low bone mineral density, which is treatable but underdiagnosed. The purpose of this case-control study is to determine whether lumbar vertebral trabecular attenuation, vertebral compression fractures, and femoral neck T scores readily derived from abdominopelvic CT scans obtained for various indications are associated with future hip fragility fracture. MATERIALS AND METHODS: A cohort of 204 patients with hip fracture (130 women and 74 men; mean age, 74...
June 1, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28560501/relationship-of-bone-mineral-density-with-valvular-and-annular-calcification-in-community-dwelling-older-people-the-cardiovascular-health-study
#16
Daniele Massera, Shuo Xu, Traci M Bartz, Anna E Bortnick, Joachim H Ix, Michel Chonchol, David S Owens, Eddy Barasch, Julius M Gardin, John S Gottdiener, John R Robbins, David S Siscovick, Jorge R Kizer
Associations between bone mineral density and aortic valvular, aortic annular, and mitral annular calcification were investigated in a cross-sectional analysis of a population-based cohort of 1497 older adults. Although there was no association between continuous bone mineral density and outcomes, a significant association between osteoporosis and aortic valvular calcification in men was found. INTRODUCTION: The process of cardiac calcification bears a resemblance to skeletal bone metabolism and its regulation...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28554377/pharmacological-treatment-options-for-low-bone-mineral-density-and-secondary-osteoporosis-in-anorexia-nervosa-a-systematic-review-of-the-literature
#17
REVIEW
Lauren Robinson, Victoria Aldridge, Emma M Clark, Madhusmita Misra, Nadia Micali
OBJECTIVE: Although there are several evidence-based treatments available to increase Bone Mineral Density (BMD) and reduce fracture risk in aging men and women, there are still uncertainties regarding which treatments are efficacious in reducing lifetime fracture risk in women with Anorexia Nervosa (AN). METHODS: Medline, PsychInfo, Embase and the Cochrane Database were searched for English Language Studies. Inclusion criteria were studies of females of any age with AN who received pharmacological treatment with the primary aim to increase BMD or reduce fracture risk...
July 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28553228/how-general-practitioners-and-their-patients-adhere-to-osteoporosis-management-a-follow-up-survey-among-czech-general-practitioners
#18
Magda Vytrisalova, Tereza Touskova, Leos Fuksa, Roman Karascak, Vladimir Palicka, Svatopluk Byma, Jan Stepan
Introduction: General practitioners (GPs) are key participants in osteoporosis (OP) management. The aim was to evaluate their adherence to lege artis management of the disease, potential barriers, and to discuss differences observed in comparison with the baseline survey carried out in 2007; the focus was on secondary prevention. Methods: On behalf of two professional associations, 2-round postal survey among randomly selected GPs (>1/4 of all Czech GPs) was performed in 2014. The questionnaire covered areas concerning GP's role in the fight against OP, knowledge about OP, management of OP-related fractures, barriers to the management of OP, system- and patient-related in particular, and availability and use of information sources...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28551925/-clinical-characteristics-of-male-patients-with-osteoporosis-referred-to-the-endocrine-clinic-of-a-tertiary-hospital
#19
Gloria Tsvetov, Ilana Shraga-Slutzky, Dania Hirsch, Hiba Masri, Tzippy Shohat, Alexander Gorshtein, Ilan Shimon
INTRODUCTION: Osteoporosis in men is underdiagnosed and undertreated. The prevalence of male osteoporosis increases with age and it becomes a significant public health burden. Currently, there are a few clinical studies on male osteoporosis with limited knowledge of effective therapeutic options. AIMS: Our study aimed to characterize men with osteoporosis in a referral metabolic clinic in Rabin Medical Center at the Beilinson Campus. METHODS: In this study we retrospectively analyzed the medical records of 270 consecutive male patients with osteoporosis diagnosed and treated in our clinic during 2013...
April 2017: Harefuah
https://www.readbyqxmd.com/read/28549839/vitamin-b12-deficiency-might-be-related-to-sarcopenia-in-older-adults
#20
Esra Ates Bulut, Pinar Soysal, Ali Ekrem Aydin, Ozge Dokuzlar, Suleyman Emre Kocyigit, Ahmet Turan Isik
Sarcopenia and dynapenia are related to repeated falls, mobility restriction, depression, frailty, increased mortality and morbidity. The aim of this study is to evaluate the relationship between vitamin B12 deficiency and sarcopenia in older adults. 403 patients, who attended to outpatient clinic and underwent comprehensive geriatric assessment, were included study. All cases' skeletal muscle mass (SMM), walking speed and hand grip strength were recorded by bioimpedance, 4meter walking test and hand dynamometer respectively...
September 2017: Experimental Gerontology
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